#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9W3I9	uniprotkb:Q9VJ83	intact:EBI-88690|ensemblmetazoa:FBpp0071136	intact:EBI-164007|uniprotkb:Q8SXT4|ensemblmetazoa:FBpp0289898|ensemblmetazoa:FBpp0304599	psi-mi:q9w3i9_drome(display_long)|uniprotkb:Traf6(gene name)|psi-mi:Traf6(display_short)|uniprotkb:Traf2(gene name synonym)|uniprotkb:DTRAF2(gene name synonym)|uniprotkb:Dmel\CG10961(gene name synonym)|uniprotkb:EP325(gene name synonym)|uniprotkb:TRAF(gene name synonym)|uniprotkb:TRAF2(gene name synonym)|uniprotkb:TRAF6(gene name synonym)|uniprotkb:dTRAF2(gene name synonym)|uniprotkb:dTRAF6(gene name synonym)|uniprotkb:dTraf2(gene name synonym)|uniprotkb:dTraf6(gene name synonym)|uniprotkb:dtraf2(gene name synonym)|uniprotkb:traf2(gene name synonym)|uniprotkb:Dmel_CG10961(orf name)|uniprotkb:CG10961(orf name)	psi-mi:grnd_drome(display_long)|uniprotkb:grnd(gene name)|psi-mi:grnd(display_short)|uniprotkb:CG10176(orf name)	psi-mi:"MI:0096"(pull down)	Andersen et al. (2015)	pubmed:25874673|doi:10.1038/nature14298|imex:IM-24571	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16153898|imex:IM-24571-1|dip:DIP-199243E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_511080.2|reactome:R-DME-9020702|ensemblmetazoa:FBgn0265464(gene)|ensemblmetazoa:FBtr0071188(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0061059"(positive regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005164"(tumor necrosis factor receptor binding)|interpro:IPR017907|go:"GO:0005737"(cytoplasm)|go:"GO:0007391"(dorsal closure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010508"(positive regulation of autophagy)|interpro:IPR027139|interpro:IPR037309|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|interpro:IPR043211|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|reactome:R-DME-5689880|reactome:R-DME-5689896|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|flybase:FBgn0265464	refseq:NP_609880.2|flybase:FBgn0032682|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|rcsb pdb:6ZSY|rcsb pdb:6ZSZ|rcsb pdb:6ZT0|ensemblmetazoa:FBgn0032682(gene)|ensemblmetazoa:FBtr0300674(transcript)|ensemblmetazoa:FBtr0332321(transcript)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0010942"(positive regulation of cell death)|refseq:NP_001260538.1|dip:DIP-61584N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:Spt6HU9qjR5oE5AWpC57k4nl8bw7227	rogid:hXScU2X916NsyN0Gt9/HUidCEzg7227	rigid:2PvoJQRqgW/AX9p89+aX6H3ZAh8	false	-	mutation decreasing interaction strength:202-202|mutation decreasing interaction strength:202-202,200-200|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9VBY7	uniprotkb:Q9VJ83	intact:EBI-91754|ensemblmetazoa:FBpp0084162	intact:EBI-164007|uniprotkb:Q8SXT4|ensemblmetazoa:FBpp0289898|ensemblmetazoa:FBpp0304599	psi-mi:q9vby7_drome(display_long)|uniprotkb:veli(gene name)|psi-mi:veli(display_short)|uniprotkb:Lin7(gene name synonym)|uniprotkb:D-veli(gene name synonym)|uniprotkb:DLin-7(gene name synonym)|uniprotkb:DLin7(gene name synonym)|uniprotkb:Dmel\CG7662(gene name synonym)|uniprotkb:Dveli(gene name synonym)|uniprotkb:Flin-7(gene name synonym)|uniprotkb:Lin-7(gene name synonym)|uniprotkb:Veli(gene name synonym)|uniprotkb:d-Veli(gene name synonym)|uniprotkb:dLin-7(gene name synonym)|uniprotkb:dLin7(gene name synonym)|uniprotkb:dVeli(gene name synonym)|uniprotkb:lin-7(gene name synonym)|uniprotkb:lin7(gene name synonym)|uniprotkb:Dmel_CG7662(orf name)|uniprotkb:CG7662(orf name)	psi-mi:grnd_drome(display_long)|uniprotkb:grnd(gene name)|psi-mi:grnd(display_short)|uniprotkb:CG10176(orf name)	psi-mi:"MI:0096"(pull down)	Andersen et al. (2015)	pubmed:25874673|doi:10.1038/nature14298|imex:IM-24571	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16153947|imex:IM-24571-3|dip:DIP-199245E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_651330.1|flybase:FBgn0039269|ensemblmetazoa:FBtr0084787(transcript)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0035003"(subapical complex)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|ensemblmetazoa:FBgn0039269(gene)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|go:"GO:1903361"(protein localization to basolateral plasma membrane)|dip:DIP-61585N	refseq:NP_609880.2|flybase:FBgn0032682|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|rcsb pdb:6ZSY|rcsb pdb:6ZSZ|rcsb pdb:6ZT0|ensemblmetazoa:FBgn0032682(gene)|ensemblmetazoa:FBtr0300674(transcript)|ensemblmetazoa:FBtr0332321(transcript)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0010942"(positive regulation of cell death)|refseq:NP_001260538.1|dip:DIP-61584N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:qrTQ/IxdYSptcelU9NxWqhxzanU7227	rogid:hXScU2X916NsyN0Gt9/HUidCEzg7227	rigid:ok3uipz4L91RJwgy3H0thIwQk0A	false	sufficient binding region:85-195	glutathione s tranferase tag:n-n|sufficient binding region:125-168	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q8MUJ1	uniprotkb:Q9VJ83	intact:EBI-108054|intact:EBI-3423810|intact:EBI-516974|uniprotkb:Q8IGD3|uniprotkb:Q8MRW2|uniprotkb:Q8MY88|ensemblmetazoa:FBpp0087493	intact:EBI-164007|uniprotkb:Q8SXT4|ensemblmetazoa:FBpp0289898|ensemblmetazoa:FBpp0304599	psi-mi:eiger_drome(display_long)|uniprotkb:egr(gene name)|psi-mi:egr(display_short)|uniprotkb:Darth(gene name synonym)|uniprotkb:CG12919(orf name)	psi-mi:grnd_drome(display_long)|uniprotkb:grnd(gene name)|psi-mi:grnd(display_short)|uniprotkb:CG10176(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Andersen et al. (2015)	pubmed:25874673|doi:10.1038/nature14298|imex:IM-24571	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16153970|imex:IM-24571-4|dip:DIP-199244E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_724878.2|flybase:FBgn0033483|refseq:NP_995791.1|ensemblmetazoa:FBgn0033483(gene)|ensemblmetazoa:FBtr0088405(transcript)|go:"GO:0002347"(response to tumor cell)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035006"(melanization defense response)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045087"(innate immune response)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045176"(apical protein localization)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|rcsb pdb:6ZT0|reactome:R-DME-450520	refseq:NP_609880.2|flybase:FBgn0032682|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|rcsb pdb:6ZSY|rcsb pdb:6ZSZ|rcsb pdb:6ZT0|ensemblmetazoa:FBgn0032682(gene)|ensemblmetazoa:FBtr0300674(transcript)|ensemblmetazoa:FBtr0332321(transcript)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0010942"(positive regulation of cell death)|refseq:NP_001260538.1|dip:DIP-61584N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/08	2017/08/10	rogid:M6woa0RRnSQtL56wC0YDEog/IHc7227	rogid:hXScU2X916NsyN0Gt9/HUidCEzg7227	rigid:JZSixlVxV19MVattl+lchVxEe/U	false	ha tag:n-n	flag tag:c-c|sufficient binding region:125-241	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9W3I9	uniprotkb:Q9VJ83	intact:EBI-88690|ensemblmetazoa:FBpp0071136	intact:EBI-164007|uniprotkb:Q8SXT4|ensemblmetazoa:FBpp0289898|ensemblmetazoa:FBpp0304599	psi-mi:q9w3i9_drome(display_long)|uniprotkb:Traf6(gene name)|psi-mi:Traf6(display_short)|uniprotkb:Traf2(gene name synonym)|uniprotkb:DTRAF2(gene name synonym)|uniprotkb:Dmel\CG10961(gene name synonym)|uniprotkb:EP325(gene name synonym)|uniprotkb:TRAF(gene name synonym)|uniprotkb:TRAF2(gene name synonym)|uniprotkb:TRAF6(gene name synonym)|uniprotkb:dTRAF2(gene name synonym)|uniprotkb:dTRAF6(gene name synonym)|uniprotkb:dTraf2(gene name synonym)|uniprotkb:dTraf6(gene name synonym)|uniprotkb:dtraf2(gene name synonym)|uniprotkb:traf2(gene name synonym)|uniprotkb:Dmel_CG10961(orf name)|uniprotkb:CG10961(orf name)	psi-mi:grnd_drome(display_long)|uniprotkb:grnd(gene name)|psi-mi:grnd(display_short)|uniprotkb:CG10176(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Andersen et al. (2015)	pubmed:25874673|doi:10.1038/nature14298|imex:IM-24571	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16153993|imex:IM-24571-5|dip:DIP-199243E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_511080.2|reactome:R-DME-9020702|ensemblmetazoa:FBgn0265464(gene)|ensemblmetazoa:FBtr0071188(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0061059"(positive regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005164"(tumor necrosis factor receptor binding)|interpro:IPR017907|go:"GO:0005737"(cytoplasm)|go:"GO:0007391"(dorsal closure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010508"(positive regulation of autophagy)|interpro:IPR027139|interpro:IPR037309|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|interpro:IPR043211|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|reactome:R-DME-5689880|reactome:R-DME-5689896|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045752"(positive regulation of Toll signaling pathway)|flybase:FBgn0265464	refseq:NP_609880.2|flybase:FBgn0032682|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|rcsb pdb:6ZSY|rcsb pdb:6ZSZ|rcsb pdb:6ZT0|ensemblmetazoa:FBgn0032682(gene)|ensemblmetazoa:FBtr0300674(transcript)|ensemblmetazoa:FBtr0332321(transcript)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0010942"(positive regulation of cell death)|refseq:NP_001260538.1|dip:DIP-61584N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/08	2017/08/10	rogid:Spt6HU9qjR5oE5AWpC57k4nl8bw7227	rogid:hXScU2X916NsyN0Gt9/HUidCEzg7227	rigid:2PvoJQRqgW/AX9p89+aX6H3ZAh8	false	ha tag:n-n	mutation disrupting interaction strength:202-202|flag tag:c-c|sufficient binding region:125-241	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9VBY7	uniprotkb:Q9VJ83	intact:EBI-91754|ensemblmetazoa:FBpp0084162	intact:EBI-164007|uniprotkb:Q8SXT4|ensemblmetazoa:FBpp0289898|ensemblmetazoa:FBpp0304599	psi-mi:q9vby7_drome(display_long)|uniprotkb:veli(gene name)|psi-mi:veli(display_short)|uniprotkb:Lin7(gene name synonym)|uniprotkb:D-veli(gene name synonym)|uniprotkb:DLin-7(gene name synonym)|uniprotkb:DLin7(gene name synonym)|uniprotkb:Dmel\CG7662(gene name synonym)|uniprotkb:Dveli(gene name synonym)|uniprotkb:Flin-7(gene name synonym)|uniprotkb:Lin-7(gene name synonym)|uniprotkb:Veli(gene name synonym)|uniprotkb:d-Veli(gene name synonym)|uniprotkb:dLin-7(gene name synonym)|uniprotkb:dLin7(gene name synonym)|uniprotkb:dVeli(gene name synonym)|uniprotkb:lin-7(gene name synonym)|uniprotkb:lin7(gene name synonym)|uniprotkb:Dmel_CG7662(orf name)|uniprotkb:CG7662(orf name)	psi-mi:grnd_drome(display_long)|uniprotkb:grnd(gene name)|psi-mi:grnd(display_short)|uniprotkb:CG10176(orf name)	psi-mi:"MI:0096"(pull down)	Andersen et al. (2015)	pubmed:25874673|doi:10.1038/nature14298|imex:IM-24571	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16154019|imex:IM-24571-6|dip:DIP-199245E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_651330.1|flybase:FBgn0039269|ensemblmetazoa:FBtr0084787(transcript)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0035003"(subapical complex)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|ensemblmetazoa:FBgn0039269(gene)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|go:"GO:1903361"(protein localization to basolateral plasma membrane)|dip:DIP-61585N	refseq:NP_609880.2|flybase:FBgn0032682|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|rcsb pdb:6ZSY|rcsb pdb:6ZSZ|rcsb pdb:6ZT0|ensemblmetazoa:FBgn0032682(gene)|ensemblmetazoa:FBtr0300674(transcript)|ensemblmetazoa:FBtr0332321(transcript)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0010942"(positive regulation of cell death)|refseq:NP_001260538.1|dip:DIP-61584N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:qrTQ/IxdYSptcelU9NxWqhxzanU7227	rogid:hXScU2X916NsyN0Gt9/HUidCEzg7227	rigid:ok3uipz4L91RJwgy3H0thIwQk0A	false	sufficient binding region:85-195	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q8MUJ1	uniprotkb:Q9VJ83	intact:EBI-108054|intact:EBI-3423810|intact:EBI-516974|uniprotkb:Q8IGD3|uniprotkb:Q8MRW2|uniprotkb:Q8MY88|ensemblmetazoa:FBpp0087493	intact:EBI-164007|uniprotkb:Q8SXT4|ensemblmetazoa:FBpp0289898|ensemblmetazoa:FBpp0304599	psi-mi:eiger_drome(display_long)|uniprotkb:egr(gene name)|psi-mi:egr(display_short)|uniprotkb:Darth(gene name synonym)|uniprotkb:CG12919(orf name)	psi-mi:grnd_drome(display_long)|uniprotkb:grnd(gene name)|psi-mi:grnd(display_short)|uniprotkb:CG10176(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Andersen et al. (2015)	pubmed:25874673|doi:10.1038/nature14298|imex:IM-24571	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16154040|imex:IM-24571-7|dip:DIP-199244E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_724878.2|flybase:FBgn0033483|refseq:NP_995791.1|ensemblmetazoa:FBgn0033483(gene)|ensemblmetazoa:FBtr0088405(transcript)|go:"GO:0002347"(response to tumor cell)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035006"(melanization defense response)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045087"(innate immune response)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045176"(apical protein localization)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|rcsb pdb:6ZT0|reactome:R-DME-450520	refseq:NP_609880.2|flybase:FBgn0032682|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|rcsb pdb:6ZSY|rcsb pdb:6ZSZ|rcsb pdb:6ZT0|ensemblmetazoa:FBgn0032682(gene)|ensemblmetazoa:FBtr0300674(transcript)|ensemblmetazoa:FBtr0332321(transcript)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0010942"(positive regulation of cell death)|refseq:NP_001260538.1|dip:DIP-61584N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/08	2017/08/10	rogid:M6woa0RRnSQtL56wC0YDEog/IHc7227	rogid:hXScU2X916NsyN0Gt9/HUidCEzg7227	rigid:JZSixlVxV19MVattl+lchVxEe/U	false	ha tag:n-n|necessary binding region:278-415	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8MUJ1	uniprotkb:Q9VJ83	intact:EBI-108054|intact:EBI-3423810|intact:EBI-516974|uniprotkb:Q8IGD3|uniprotkb:Q8MRW2|uniprotkb:Q8MY88|ensemblmetazoa:FBpp0087493	intact:EBI-164007|uniprotkb:Q8SXT4|ensemblmetazoa:FBpp0289898|ensemblmetazoa:FBpp0304599	psi-mi:eiger_drome(display_long)|uniprotkb:egr(gene name)|psi-mi:egr(display_short)|uniprotkb:Darth(gene name synonym)|uniprotkb:CG12919(orf name)	psi-mi:grnd_drome(display_long)|uniprotkb:grnd(gene name)|psi-mi:grnd(display_short)|uniprotkb:CG10176(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Andersen et al. (2015)	pubmed:25874673|doi:10.1038/nature14298|imex:IM-24571	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16153924|imex:IM-24571-2|dip:DIP-199244E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_724878.2|flybase:FBgn0033483|refseq:NP_995791.1|ensemblmetazoa:FBgn0033483(gene)|ensemblmetazoa:FBtr0088405(transcript)|go:"GO:0002347"(response to tumor cell)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035006"(melanization defense response)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045087"(innate immune response)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045176"(apical protein localization)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|rcsb pdb:6ZT0|reactome:R-DME-450520	refseq:NP_609880.2|flybase:FBgn0032682|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|rcsb pdb:6ZSY|rcsb pdb:6ZSZ|rcsb pdb:6ZT0|ensemblmetazoa:FBgn0032682(gene)|ensemblmetazoa:FBtr0300674(transcript)|ensemblmetazoa:FBtr0332321(transcript)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0010942"(positive regulation of cell death)|refseq:NP_001260538.1|dip:DIP-61584N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/08	2017/08/10	rogid:M6woa0RRnSQtL56wC0YDEog/IHc7227	rogid:hXScU2X916NsyN0Gt9/HUidCEzg7227	rigid:JZSixlVxV19MVattl+lchVxEe/U	false	ha tag:n-n	flag tag:c-c|sufficient binding region:125-241	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8MUJ1	uniprotkb:Q9VJ83	intact:EBI-108054|intact:EBI-3423810|intact:EBI-516974|uniprotkb:Q8IGD3|uniprotkb:Q8MRW2|uniprotkb:Q8MY88|ensemblmetazoa:FBpp0087493	intact:EBI-164007|uniprotkb:Q8SXT4|ensemblmetazoa:FBpp0289898|ensemblmetazoa:FBpp0304599	psi-mi:eiger_drome(display_long)|uniprotkb:egr(gene name)|psi-mi:egr(display_short)|uniprotkb:Darth(gene name synonym)|uniprotkb:CG12919(orf name)	psi-mi:grnd_drome(display_long)|uniprotkb:grnd(gene name)|psi-mi:grnd(display_short)|uniprotkb:CG10176(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Andersen et al. (2015)	pubmed:25874673|doi:10.1038/nature14298|imex:IM-24571	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16154063|imex:IM-24571-8|dip:DIP-199244E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_724878.2|flybase:FBgn0033483|refseq:NP_995791.1|ensemblmetazoa:FBgn0033483(gene)|ensemblmetazoa:FBtr0088405(transcript)|go:"GO:0002347"(response to tumor cell)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035006"(melanization defense response)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045087"(innate immune response)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045176"(apical protein localization)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|rcsb pdb:6ZT0|reactome:R-DME-450520	refseq:NP_609880.2|flybase:FBgn0032682|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|rcsb pdb:6ZSY|rcsb pdb:6ZSZ|rcsb pdb:6ZT0|ensemblmetazoa:FBgn0032682(gene)|ensemblmetazoa:FBtr0300674(transcript)|ensemblmetazoa:FBtr0332321(transcript)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0010942"(positive regulation of cell death)|refseq:NP_001260538.1|dip:DIP-61584N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/08	2017/08/10	rogid:M6woa0RRnSQtL56wC0YDEog/IHc7227	rogid:hXScU2X916NsyN0Gt9/HUidCEzg7227	rigid:JZSixlVxV19MVattl+lchVxEe/U	false	ha tag:n-n|necessary binding region:278-415	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)