#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8BMD2 uniprotkb:P50395 intact:EBI-7089968|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689|uniprotkb:Q9CRK5|intact:MINT-5190561|uniprotkb:Q4QQM0|uniprotkb:Q6ZQ10 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 psi-mi:dzip1_mouse(display_long)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym) psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16153046|imex:IM-24228-1|dip:DIP-198774E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011243448.1|refseq:XP_006519446.1|refseq:XP_006519447.1|refseq:XP_006519454.1|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032714|mint:Q8BMD2|reactome:R-MMU-5632684|refseq:XP_017171615.1|refseq:NP_080219.2|dip:DIP-61407N ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N psi-mi:"MI:0465"(dip) comment:mint|function:May participate in spermatogenesis via its interaction with DAZ - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rigid:ZWwiY64wB3v6e61YMrfTeNCQOHE false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49841-2 uniprotkb:P49841-2 intact:EBI-15870655|ensembl:ENSP00000324806 intact:EBI-15870655|ensembl:ENSP00000324806 psi-mi:p49841-2(display_long)|uniprotkb:GSK3B(gene name)|psi-mi:GSK3B(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym)|uniprotkb:GSK-3beta2(isoform synonym)|uniprotkb:neuron-specific(isoform synonym) psi-mi:p49841-2(display_long)|uniprotkb:GSK3B(gene name)|psi-mi:GSK3B(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym)|uniprotkb:GSK-3beta2(isoform synonym)|uniprotkb:neuron-specific(isoform synonym) psi-mi:"MI:0424"(protein kinase assay) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-16153065|imex:IM-24228-2|dip:DIP-137234E - - psi-mi:"MI:0898"(putative self) psi-mi:"MI:0898"(putative self) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000082701(gene)|ensembl:ENST00000316626(transcript)|intact:EBI-373586(isoform-parent)|uniprotkb:P49841-2(isoform-parent) ensembl:ENSG00000082701(gene)|ensembl:ENST00000316626(transcript)|intact:EBI-373586(isoform-parent)|uniprotkb:P49841-2(isoform-parent) psi-mi:"MI:0465"(dip) isoform-comment:May play a specific role in axon growth and neurite outgrowth. Reduced binding to AXIN1, reduced ability to phosphorylate MAPT/TAU. isoform-comment:May play a specific role in axon growth and neurite outgrowth. Reduced binding to AXIN1, reduced ability to phosphorylate MAPT/TAU. full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:+mnJKZPToE+39AUZVr1Svxn6dvQ9606 rogid:+mnJKZPToE+39AUZVr1Svxn6dvQ9606 rigid:rhoKDDHuxkVkrGFK4qnqCBYYtxg false mutation disrupting interaction rate:85-85 mutation disrupting interaction rate:85-85 - 0 psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8BMD2 uniprotkb:P55258 intact:EBI-7089968|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689|uniprotkb:Q9CRK5|intact:MINT-5190561|uniprotkb:Q4QQM0|uniprotkb:Q6ZQ10 intact:EBI-398411|uniprotkb:Q8VCF6|ensembl:ENSMUSP00000003121 psi-mi:dzip1_mouse(display_long)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym) psi-mi:rab8a_mouse(display_long)|uniprotkb:Rab8a(gene name)|psi-mi:Rab8a(display_short)|uniprotkb:Mel(gene name synonym)|uniprotkb:Rab8(gene name synonym)|uniprotkb:Oncogene c-mel(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16153084|imex:IM-24228-3|dip:DIP-198764E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011243448.1|refseq:XP_006519446.1|refseq:XP_006519447.1|refseq:XP_006519454.1|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032714|mint:Q8BMD2|reactome:R-MMU-5632684|refseq:XP_017171615.1|refseq:NP_080219.2|dip:DIP-61407N refseq:NP_075615.2|dip:DIP-31053N|ensembl:ENSMUSG00000003037(gene)|ensembl:ENSMUST00000003121(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P55258|rcsb pdb:2FU5|reactome:R-MMU-2565942|reactome:R-MMU-5620912|reactome:R-MMU-5620916|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8876198|go:"GO:0098978"(glutamatergic synapse) psi-mi:"MI:0465"(dip) comment:mint|function:May participate in spermatogenesis via its interaction with DAZ - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/08 2017/08/10 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rogid:SE+1h+U6C8cAN2UTBIDapsUt4zA10090 rigid:iI32qgPNit/snlYNVLcr0pcC0Ys false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BMD2-1 uniprotkb:P50395 intact:EBI-16153101|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 psi-mi:q8bmd2-1(display_long)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym) psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16153108|imex:IM-24228-4|dip:DIP-198774E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7089968(isoform-parent)|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript) ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rigid:ZWwiY64wB3v6e61YMrfTeNCQOHE false green fluorescent protein tag:?-?|sufficient binding region:1-600|sufficient binding region:430-852 myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P55258 uniprotkb:P50395 intact:EBI-398411|uniprotkb:Q8VCF6|ensembl:ENSMUSP00000003121 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 psi-mi:rab8a_mouse(display_long)|uniprotkb:Rab8a(gene name)|psi-mi:Rab8a(display_short)|uniprotkb:Mel(gene name synonym)|uniprotkb:Rab8(gene name synonym)|uniprotkb:Oncogene c-mel(gene name synonym) psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16153135|imex:IM-24228-5|dip:DIP-198770E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075615.2|dip:DIP-31053N|ensembl:ENSMUSG00000003037(gene)|ensembl:ENSMUST00000003121(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P55258|rcsb pdb:2FU5|reactome:R-MMU-2565942|reactome:R-MMU-5620912|reactome:R-MMU-5620916|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8876198|go:"GO:0098978"(glutamatergic synapse) ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:SE+1h+U6C8cAN2UTBIDapsUt4zA10090 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rigid:t+gfuBk0+nYeT2iSuOpLhvN4Cqk false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BMD2-1 uniprotkb:P49841-2 intact:EBI-16153101|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689 intact:EBI-15870655|ensembl:ENSP00000324806 psi-mi:q8bmd2-1(display_long)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym) psi-mi:p49841-2(display_long)|uniprotkb:GSK3B(gene name)|psi-mi:GSK3B(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym)|uniprotkb:GSK-3beta2(isoform synonym)|uniprotkb:neuron-specific(isoform synonym) psi-mi:"MI:0424"(protein kinase assay) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-16153154|imex:IM-24228-6|dip:DIP-198773E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7089968(isoform-parent)|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript) ensembl:ENSG00000082701(gene)|ensembl:ENST00000316626(transcript)|intact:EBI-373586(isoform-parent)|uniprotkb:P49841-2(isoform-parent) psi-mi:"MI:0465"(dip) - isoform-comment:May play a specific role in axon growth and neurite outgrowth. Reduced binding to AXIN1, reduced ability to phosphorylate MAPT/TAU. full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rogid:+mnJKZPToE+39AUZVr1Svxn6dvQ9606 rigid:D6OWZ3d77dyPzHkmUflX7GoCckY false mutation disrupting interaction rate:520-520|sufficient binding region:1-378|sufficient binding region:594-852|sufficient binding region:373-600 - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8BMD2 uniprotkb:P55258 intact:EBI-7089968|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689|uniprotkb:Q9CRK5|intact:MINT-5190561|uniprotkb:Q4QQM0|uniprotkb:Q6ZQ10 intact:EBI-398411|uniprotkb:Q8VCF6|ensembl:ENSMUSP00000003121 psi-mi:dzip1_mouse(display_long)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym) psi-mi:rab8a_mouse(display_long)|uniprotkb:Rab8a(gene name)|psi-mi:Rab8a(display_short)|uniprotkb:Mel(gene name synonym)|uniprotkb:Rab8(gene name synonym)|uniprotkb:Oncogene c-mel(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16153180|imex:IM-24228-7|dip:DIP-198764E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011243448.1|refseq:XP_006519446.1|refseq:XP_006519447.1|refseq:XP_006519454.1|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032714|mint:Q8BMD2|reactome:R-MMU-5632684|refseq:XP_017171615.1|refseq:NP_080219.2|dip:DIP-61407N refseq:NP_075615.2|dip:DIP-31053N|ensembl:ENSMUSG00000003037(gene)|ensembl:ENSMUST00000003121(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P55258|rcsb pdb:2FU5|reactome:R-MMU-2565942|reactome:R-MMU-5620912|reactome:R-MMU-5620916|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8876198|go:"GO:0098978"(glutamatergic synapse) psi-mi:"MI:0465"(dip) comment:mint|function:May participate in spermatogenesis via its interaction with DAZ - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/08 2017/08/10 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rogid:SE+1h+U6C8cAN2UTBIDapsUt4zA10090 rigid:iI32qgPNit/snlYNVLcr0pcC0Ys false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BMD2-1 uniprotkb:P49841-2 intact:EBI-16153101|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689 intact:EBI-15870655|ensembl:ENSP00000324806 psi-mi:q8bmd2-1(display_long)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym) psi-mi:p49841-2(display_long)|uniprotkb:GSK3B(gene name)|psi-mi:GSK3B(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym)|uniprotkb:GSK-3beta2(isoform synonym)|uniprotkb:neuron-specific(isoform synonym) psi-mi:"MI:0424"(protein kinase assay) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-16153197|imex:IM-24228-8|dip:DIP-198773E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7089968(isoform-parent)|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript) ensembl:ENSG00000082701(gene)|ensembl:ENST00000316626(transcript)|intact:EBI-373586(isoform-parent)|uniprotkb:P49841-2(isoform-parent) psi-mi:"MI:0465"(dip) - isoform-comment:May play a specific role in axon growth and neurite outgrowth. Reduced binding to AXIN1, reduced ability to phosphorylate MAPT/TAU. full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rogid:+mnJKZPToE+39AUZVr1Svxn6dvQ9606 rigid:D6OWZ3d77dyPzHkmUflX7GoCckY false sufficient binding region:373-600 mutation disrupting interaction rate:85-85 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P61007 uniprotkb:P50395 intact:EBI-7473289|uniprotkb:P24407|intact:MINT-155827|ensembl:ENSCAFP00000023207|ensembl:ENSCAFP00030035461|ensembl:ENSCAFP00040030179 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 psi-mi:rab8a_canlf(display_long)|uniprotkb:RAB8A(gene name)|psi-mi:RAB8A(display_short)|uniprotkb:MEL(gene name synonym)|uniprotkb:RAB8(gene name synonym)|uniprotkb:Oncogene c-mel(gene name synonym) psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16153219|imex:IM-24228-9|dip:DIP-198768E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003152.1|ensembl:ENSCAFG00000015782(gene)|ensembl:ENSCAFG00030022117(gene)|ensembl:ENSCAFG00040018726(gene)|ensembl:ENSCAFT00000025007(transcript)|ensembl:ENSCAFT00030040626(transcript)|ensembl:ENSCAFT00040034659(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-CFA-2565942|reactome:R-CFA-5620912|reactome:R-CFA-5620916|reactome:R-CFA-8854214|reactome:R-CFA-8873719|reactome:R-CFA-8876198|dip:DIP-42002N ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N psi-mi:"MI:0465"(dip) comment:mint|function:May be involved in vesicular trafficking and neurotransmitter release - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:ucWVK9e1z44F2XnAJatPYm8IRlk9615 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rigid:YAlDFj0XwA95LLlFY48Rhkiy3kQ false green fluorescent protein tag:n-n|mutation:22-22 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BMD2 uniprotkb:Q61598 intact:EBI-7089968|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689|uniprotkb:Q9CRK5|intact:MINT-5190561|uniprotkb:Q4QQM0|uniprotkb:Q6ZQ10 intact:EBI-6665490|ensembl:ENSMUSP00000152454|uniprotkb:Q541Z9|uniprotkb:Q8C530|uniprotkb:Q9D8M9 psi-mi:dzip1_mouse(display_long)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym) psi-mi:gdib_mouse(display_long)|uniprotkb:Gdi2(gene name)|psi-mi:Gdi2(display_short)|uniprotkb:Gdi3(gene name synonym)|uniprotkb:GDI-3(gene name synonym)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16153241|imex:IM-24228-10|dip:DIP-198767E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011243448.1|refseq:XP_006519446.1|refseq:XP_006519447.1|refseq:XP_006519454.1|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032714|mint:Q8BMD2|reactome:R-MMU-5632684|refseq:XP_017171615.1|refseq:NP_080219.2|dip:DIP-61407N go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:Q61598|reactome:R-MMU-6798695|reactome:R-MMU-8876198|ensembl:ENSMUSG00000021218(gene)|ensembl:ENSMUST00000223396(transcript)|refseq:NP_032138.3|dip:DIP-348N psi-mi:"MI:0465"(dip) comment:mint|function:May participate in spermatogenesis via its interaction with DAZ - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/08 2017/08/10 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rogid:+ngZz9q02lDEdFO543w/yl6chgc10090 rigid:3e35m89/CiycSpMltv1SjLBE9hc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P61007 uniprotkb:Q8BMD2-1 intact:EBI-7473289|uniprotkb:P24407|intact:MINT-155827|ensembl:ENSCAFP00000023207|ensembl:ENSCAFP00030035461|ensembl:ENSCAFP00040030179 intact:EBI-16153101|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689 psi-mi:rab8a_canlf(display_long)|uniprotkb:RAB8A(gene name)|psi-mi:RAB8A(display_short)|uniprotkb:MEL(gene name synonym)|uniprotkb:RAB8(gene name synonym)|uniprotkb:Oncogene c-mel(gene name synonym) psi-mi:q8bmd2-1(display_long)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16153303|imex:IM-24228-13|dip:DIP-198765E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003152.1|ensembl:ENSCAFG00000015782(gene)|ensembl:ENSCAFG00030022117(gene)|ensembl:ENSCAFG00040018726(gene)|ensembl:ENSCAFT00000025007(transcript)|ensembl:ENSCAFT00030040626(transcript)|ensembl:ENSCAFT00040034659(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-CFA-2565942|reactome:R-CFA-5620912|reactome:R-CFA-5620916|reactome:R-CFA-8854214|reactome:R-CFA-8873719|reactome:R-CFA-8876198|dip:DIP-42002N intact:EBI-7089968(isoform-parent)|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript) psi-mi:"MI:0465"(dip) comment:mint|function:May be involved in vesicular trafficking and neurotransmitter release - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:ucWVK9e1z44F2XnAJatPYm8IRlk9615 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rigid:DXz5PD3kW7/acO6P/FlcSYfT0Us false green fluorescent protein tag:n-n|mutation increasing interaction strength:22-22|mutation disrupting interaction strength:67-67 myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P61007 uniprotkb:P50395 intact:EBI-7473289|uniprotkb:P24407|intact:MINT-155827|ensembl:ENSCAFP00000023207|ensembl:ENSCAFP00030035461|ensembl:ENSCAFP00040030179 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 psi-mi:rab8a_canlf(display_long)|uniprotkb:RAB8A(gene name)|psi-mi:RAB8A(display_short)|uniprotkb:MEL(gene name synonym)|uniprotkb:RAB8(gene name synonym)|uniprotkb:Oncogene c-mel(gene name synonym) psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16153279|imex:IM-24228-12|dip:DIP-198768E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003152.1|ensembl:ENSCAFG00000015782(gene)|ensembl:ENSCAFG00030022117(gene)|ensembl:ENSCAFG00040018726(gene)|ensembl:ENSCAFT00000025007(transcript)|ensembl:ENSCAFT00030040626(transcript)|ensembl:ENSCAFT00040034659(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-CFA-2565942|reactome:R-CFA-5620912|reactome:R-CFA-5620916|reactome:R-CFA-8854214|reactome:R-CFA-8873719|reactome:R-CFA-8876198|dip:DIP-42002N ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N psi-mi:"MI:0465"(dip) comment:mint|function:May be involved in vesicular trafficking and neurotransmitter release - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:ucWVK9e1z44F2XnAJatPYm8IRlk9615 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rigid:YAlDFj0XwA95LLlFY48Rhkiy3kQ false green fluorescent protein tag:n-n|mutation:22-22 myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q86YF9 uniprotkb:P49841-2 intact:EBI-998108|uniprotkb:Q8WY45|uniprotkb:Q8WY46|uniprotkb:Q9UGA5|uniprotkb:Q9Y2K0|uniprotkb:Q5W078|uniprotkb:Q5W079|intact:EBI-28972311|ensembl:ENSP00000257312|ensembl:ENSP00000366025 intact:EBI-15870655|ensembl:ENSP00000324806 psi-mi:dzip1_human(display_long)|uniprotkb:DAZ-interacting protein 1/2(gene name synonym)|uniprotkb:DZIP1(gene name)|psi-mi:DZIP1(display_short)|uniprotkb:DZIP(gene name synonym)|uniprotkb:DZIP2(gene name synonym)|uniprotkb:KIAA0996(gene name synonym) psi-mi:p49841-2(display_long)|uniprotkb:GSK3B(gene name)|psi-mi:GSK3B(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym)|uniprotkb:GSK-3beta2(isoform synonym)|uniprotkb:neuron-specific(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16153258|imex:IM-24228-11|dip:DIP-198772E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000257312|ensembl:ENST00000361156|ensembl:ENSP00000355018|ensembl:ENST00000361396|ensembl:ENSP00000355175|ensembl:ENSP00000366025|ensembl:ENST00000466569|ensembl:ENSP00000431168|ensembl:ENSG00000134874(gene)|ensembl:ENST00000347108(transcript)|ensembl:ENST00000376829(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032714|reactome:R-HSA-5632684|refseq:NP_055749.1|refseq:NP_945319.1|dip:DIP-35710N ensembl:ENSG00000082701(gene)|ensembl:ENST00000316626(transcript)|intact:EBI-373586(isoform-parent)|uniprotkb:P49841-2(isoform-parent) psi-mi:"MI:0465"(dip) - isoform-comment:May play a specific role in axon growth and neurite outgrowth. Reduced binding to AXIN1, reduced ability to phosphorylate MAPT/TAU. full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:Ai+aFcCrkSRsORpfO7EATMi0HHg9606 rogid:+mnJKZPToE+39AUZVr1Svxn6dvQ9606 rigid:p6TISfWiuD2zRZsDs1tAw7BDHAw false - green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BMD2 uniprotkb:Q9WV60 intact:EBI-7089968|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689|uniprotkb:Q9CRK5|intact:MINT-5190561|uniprotkb:Q4QQM0|uniprotkb:Q6ZQ10 intact:EBI-400793|ensembl:ENSMUSP00000023507 psi-mi:dzip1_mouse(display_long)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym) psi-mi:gsk3b_mouse(display_long)|uniprotkb:Gsk3b(gene name)|psi-mi:Gsk3b(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16153332|imex:IM-24228-14|dip:DIP-198771E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011243448.1|refseq:XP_006519446.1|refseq:XP_006519447.1|refseq:XP_006519454.1|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032714|mint:Q8BMD2|reactome:R-MMU-5632684|refseq:XP_017171615.1|refseq:NP_080219.2|dip:DIP-61407N refseq:NP_062801.1|dip:DIP-32446N|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006983"(ER overload response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014043"(negative regulation of neuron maturation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0034452"(dynactin binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033573|interpro:IPR039192|mint:Q9WV60|rcsb pdb:4NU1|rcsb pdb:5AIR|rcsb pdb:6AE3|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-3371453|reactome:R-MMU-399956|reactome:R-MMU-4641262|reactome:R-MMU-5250924|reactome:R-MMU-5610785|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044027"(hypermethylation of CpG island)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046849"(bone remodeling)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071109"(superior temporal gyrus development)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090290"(positive regulation of osteoclast proliferation)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0106027"(neuron projection organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0150101"(regulation of microtubule anchoring at centrosome)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904780"(negative regulation of protein localization to centrosome)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000171"(negative regulation of dendrite development)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|ensembl:ENSMUSG00000022812(gene)|ensembl:ENSMUST00000023507(transcript)|go:"GO:0000320"(re-entry into mitotic cell cycle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0006349"(regulation of gene expression by genomic imprinting) psi-mi:"MI:0465"(dip) comment:mint|function:May participate in spermatogenesis via its interaction with DAZ - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/08 2017/08/10 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rogid:FKe0WkOBBYU0vIJLmcFNMJ+KVHA10090 rigid:5weP0ZaA8SjrK3SHfyA37F92lUI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P61007 uniprotkb:Q8BMD2-1 intact:EBI-7473289|uniprotkb:P24407|intact:MINT-155827|ensembl:ENSCAFP00000023207|ensembl:ENSCAFP00030035461|ensembl:ENSCAFP00040030179 intact:EBI-16153101|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689 psi-mi:rab8a_canlf(display_long)|uniprotkb:RAB8A(gene name)|psi-mi:RAB8A(display_short)|uniprotkb:MEL(gene name synonym)|uniprotkb:RAB8(gene name synonym)|uniprotkb:Oncogene c-mel(gene name synonym) psi-mi:q8bmd2-1(display_long)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16153349|imex:IM-24228-15|dip:DIP-198765E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003152.1|ensembl:ENSCAFG00000015782(gene)|ensembl:ENSCAFG00030022117(gene)|ensembl:ENSCAFG00040018726(gene)|ensembl:ENSCAFT00000025007(transcript)|ensembl:ENSCAFT00030040626(transcript)|ensembl:ENSCAFT00040034659(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-CFA-2565942|reactome:R-CFA-5620912|reactome:R-CFA-5620916|reactome:R-CFA-8854214|reactome:R-CFA-8873719|reactome:R-CFA-8876198|dip:DIP-42002N intact:EBI-7089968(isoform-parent)|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript) psi-mi:"MI:0465"(dip) comment:mint|function:May be involved in vesicular trafficking and neurotransmitter release - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:ucWVK9e1z44F2XnAJatPYm8IRlk9615 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rigid:DXz5PD3kW7/acO6P/FlcSYfT0Us false green fluorescent protein tag:n-n|mutation:22-22 myc tag:?-?|sufficient binding region:1-600|sufficient binding region:430-852 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P50395 uniprotkb:Q8BMD2 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 intact:EBI-7089968|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689|uniprotkb:Q9CRK5|intact:MINT-5190561|uniprotkb:Q4QQM0|uniprotkb:Q6ZQ10 psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:dzip1_mouse(display_long)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16153379|imex:IM-24228-16|dip:DIP-198769E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N refseq:XP_011243448.1|refseq:XP_006519446.1|refseq:XP_006519447.1|refseq:XP_006519454.1|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032714|mint:Q8BMD2|reactome:R-MMU-5632684|refseq:XP_017171615.1|refseq:NP_080219.2|dip:DIP-61407N psi-mi:"MI:0465"(dip) - comment:mint|function:May participate in spermatogenesis via its interaction with DAZ full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rigid:Bj8CPEZtAPzaLF5hknaYFrtVDK0 false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P50395 uniprotkb:P55258 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 intact:EBI-398411|uniprotkb:Q8VCF6|ensembl:ENSMUSP00000003121 psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:rab8a_mouse(display_long)|uniprotkb:Rab8a(gene name)|psi-mi:Rab8a(display_short)|uniprotkb:Mel(gene name synonym)|uniprotkb:Rab8(gene name synonym)|uniprotkb:Oncogene c-mel(gene name synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16153379|imex:IM-24228-16|dip:DIP-198769E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N refseq:NP_075615.2|dip:DIP-31053N|ensembl:ENSMUSG00000003037(gene)|ensembl:ENSMUST00000003121(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P55258|rcsb pdb:2FU5|reactome:R-MMU-2565942|reactome:R-MMU-5620912|reactome:R-MMU-5620916|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8876198|go:"GO:0098978"(glutamatergic synapse) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rogid:SE+1h+U6C8cAN2UTBIDapsUt4zA10090 rigid:Bj8CPEZtAPzaLF5hknaYFrtVDK0 false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BMD2-1 uniprotkb:P49841-2 intact:EBI-16153101|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689 intact:EBI-15870655|ensembl:ENSP00000324806 psi-mi:q8bmd2-1(display_long)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym) psi-mi:p49841-2(display_long)|uniprotkb:GSK3B(gene name)|psi-mi:GSK3B(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym)|uniprotkb:GSK-3beta2(isoform synonym)|uniprotkb:neuron-specific(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16153399|imex:IM-24228-17|dip:DIP-198773E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7089968(isoform-parent)|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript) ensembl:ENSG00000082701(gene)|ensembl:ENST00000316626(transcript)|intact:EBI-373586(isoform-parent)|uniprotkb:P49841-2(isoform-parent) psi-mi:"MI:0465"(dip) - isoform-comment:May play a specific role in axon growth and neurite outgrowth. Reduced binding to AXIN1, reduced ability to phosphorylate MAPT/TAU. full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rogid:+mnJKZPToE+39AUZVr1Svxn6dvQ9606 rigid:D6OWZ3d77dyPzHkmUflX7GoCckY false myc tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P61027 uniprotkb:Q8BMD2-1 intact:EBI-911581|uniprotkb:O88386|uniprotkb:Q9D7X6|ensembl:ENSMUSP00000021001 intact:EBI-16153101|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689 psi-mi:rab10_mouse(display_long)|uniprotkb:Rab10(gene name)|psi-mi:Rab10(display_short) psi-mi:q8bmd2-1(display_long)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16153450|imex:IM-24228-19|dip:DIP-198766E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057885.1|dip:DIP-37720N|ensembl:ENSMUSG00000020671(gene)|ensembl:ENSMUST00000021001(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031489"(myosin V binding)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051021"(GDP-dissociation inhibitor binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61027|reactome:R-MMU-6798695|reactome:R-MMU-8873719|reactome:R-MMU-8876198 intact:EBI-7089968(isoform-parent)|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE10090 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rigid:aWu71D+Re5ipdXhHnKxKfzPHuZU false green fluorescent protein tag:n-n myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P50395 uniprotkb:P55258 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 intact:EBI-398411|uniprotkb:Q8VCF6|ensembl:ENSMUSP00000003121 psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:rab8a_mouse(display_long)|uniprotkb:Rab8a(gene name)|psi-mi:Rab8a(display_short)|uniprotkb:Mel(gene name synonym)|uniprotkb:Rab8(gene name synonym)|uniprotkb:Oncogene c-mel(gene name synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16153424|imex:IM-24228-18|dip:DIP-198769E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N refseq:NP_075615.2|dip:DIP-31053N|ensembl:ENSMUSG00000003037(gene)|ensembl:ENSMUST00000003121(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P55258|rcsb pdb:2FU5|reactome:R-MMU-2565942|reactome:R-MMU-5620912|reactome:R-MMU-5620916|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8876198|go:"GO:0098978"(glutamatergic synapse) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rogid:SE+1h+U6C8cAN2UTBIDapsUt4zA10090 rigid:Bj8CPEZtAPzaLF5hknaYFrtVDK0 false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P50395 uniprotkb:Q8BMD2-1 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 intact:EBI-16153101|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689 psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:q8bmd2-1(display_long)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16153424|imex:IM-24228-18|dip:DIP-198769E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N intact:EBI-7089968(isoform-parent)|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rigid:Bj8CPEZtAPzaLF5hknaYFrtVDK0 false glutathione s tranferase tag:n-n his tag:?-?|sufficient binding region:430-600 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P50395 uniprotkb:P61006 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 intact:EBI-722293|intact:EBI-1054454|uniprotkb:P24407|intact:EBI-2798283|uniprotkb:Q6FHV5|uniprotkb:B4DEK7|ensembl:ENSP00000300935 psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:rab8a_human(display_long)|uniprotkb:Oncogene c-mel(gene name synonym)|uniprotkb:RAB8A(gene name)|psi-mi:RAB8A(display_short)|uniprotkb:MEL(gene name synonym)|uniprotkb:RAB8(gene name synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16153473|imex:IM-24228-20|dip:DIP-198775E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N refseq:NP_005361.2|dip:DIP-43703N|ensembl:ENSG00000167461(gene)|ensembl:ENST00000300935(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61006|rcsb pdb:3QBT|rcsb pdb:3TNF|rcsb pdb:4LHV|rcsb pdb:4LHW|rcsb pdb:4LHX|rcsb pdb:4LHY|go:"GO:0014069"(postsynaptic density)|go:"GO:0017157"(regulation of exocytosis)|rcsb pdb:4LHZ|rcsb pdb:4LI0|rcsb pdb:5SZI|rcsb pdb:6RIR|rcsb pdb:6SQ2|rcsb pdb:6STF|rcsb pdb:6STG|rcsb pdb:6WHE|rcsb pdb:6ZSI|rcsb pdb:6ZSJ|rcsb pdb:7BWT|rcsb pdb:7LWB|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rogid:ucWVK9e1z44F2XnAJatPYm8IRlk9606 rigid:oBdJJgOjGwWW9w1w/Vetc7iLXMA false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P50395 uniprotkb:Q8BMD2-1 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 intact:EBI-16153101|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689 psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:q8bmd2-1(display_long)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16153473|imex:IM-24228-20|dip:DIP-198775E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N intact:EBI-7089968(isoform-parent)|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rigid:oBdJJgOjGwWW9w1w/Vetc7iLXMA false glutathione s tranferase tag:n-n green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P61007 uniprotkb:Q96QF0 intact:EBI-7473289|uniprotkb:P24407|intact:MINT-155827|ensembl:ENSCAFP00000023207|ensembl:ENSCAFP00030035461|ensembl:ENSCAFP00040030179 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 psi-mi:rab8a_canlf(display_long)|uniprotkb:RAB8A(gene name)|psi-mi:RAB8A(display_short)|uniprotkb:MEL(gene name synonym)|uniprotkb:RAB8(gene name synonym)|uniprotkb:Oncogene c-mel(gene name synonym) psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16153497|imex:IM-24228-21|dip:DIP-198776E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003152.1|ensembl:ENSCAFG00000015782(gene)|ensembl:ENSCAFG00030022117(gene)|ensembl:ENSCAFG00040018726(gene)|ensembl:ENSCAFT00000025007(transcript)|ensembl:ENSCAFT00030040626(transcript)|ensembl:ENSCAFT00040034659(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-CFA-2565942|reactome:R-CFA-5620912|reactome:R-CFA-5620916|reactome:R-CFA-8854214|reactome:R-CFA-8873719|reactome:R-CFA-8876198|dip:DIP-42002N refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N psi-mi:"MI:0465"(dip) comment:mint|function:May be involved in vesicular trafficking and neurotransmitter release - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:ucWVK9e1z44F2XnAJatPYm8IRlk9615 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rigid:w6Q7XIHKtGXT0HavV8uYl0XGggg false mutation increasing interaction strength:22-22|flag tag:n-n sufficient binding region:101-316|yellow fluorescent protein tag:c-c|cyan fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8BMD2 uniprotkb:Q61598 intact:EBI-7089968|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689|uniprotkb:Q9CRK5|intact:MINT-5190561|uniprotkb:Q4QQM0|uniprotkb:Q6ZQ10 intact:EBI-6665490|ensembl:ENSMUSP00000152454|uniprotkb:Q541Z9|uniprotkb:Q8C530|uniprotkb:Q9D8M9 psi-mi:dzip1_mouse(display_long)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym) psi-mi:gdib_mouse(display_long)|uniprotkb:Gdi2(gene name)|psi-mi:Gdi2(display_short)|uniprotkb:Gdi3(gene name synonym)|uniprotkb:GDI-3(gene name synonym)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16153525|imex:IM-24228-22|dip:DIP-198767E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011243448.1|refseq:XP_006519446.1|refseq:XP_006519447.1|refseq:XP_006519454.1|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032714|mint:Q8BMD2|reactome:R-MMU-5632684|refseq:XP_017171615.1|refseq:NP_080219.2|dip:DIP-61407N go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:Q61598|reactome:R-MMU-6798695|reactome:R-MMU-8876198|ensembl:ENSMUSG00000021218(gene)|ensembl:ENSMUST00000223396(transcript)|refseq:NP_032138.3|dip:DIP-348N psi-mi:"MI:0465"(dip) comment:mint|function:May participate in spermatogenesis via its interaction with DAZ - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/08 2017/08/10 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rogid:+ngZz9q02lDEdFO543w/yl6chgc10090 rigid:3e35m89/CiycSpMltv1SjLBE9hc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P61007 uniprotkb:Q8BMD2-1 intact:EBI-7473289|uniprotkb:P24407|intact:MINT-155827|ensembl:ENSCAFP00000023207|ensembl:ENSCAFP00030035461|ensembl:ENSCAFP00040030179 intact:EBI-16153101|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689 psi-mi:rab8a_canlf(display_long)|uniprotkb:RAB8A(gene name)|psi-mi:RAB8A(display_short)|uniprotkb:MEL(gene name synonym)|uniprotkb:RAB8(gene name synonym)|uniprotkb:Oncogene c-mel(gene name synonym) psi-mi:q8bmd2-1(display_long)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2015) pubmed:25860027|doi:10.1371/journal.pbio.1002129|imex:IM-24228 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16153542|imex:IM-24228-23|dip:DIP-198765E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003152.1|ensembl:ENSCAFG00000015782(gene)|ensembl:ENSCAFG00030022117(gene)|ensembl:ENSCAFG00040018726(gene)|ensembl:ENSCAFT00000025007(transcript)|ensembl:ENSCAFT00030040626(transcript)|ensembl:ENSCAFT00040034659(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-CFA-2565942|reactome:R-CFA-5620912|reactome:R-CFA-5620916|reactome:R-CFA-8854214|reactome:R-CFA-8873719|reactome:R-CFA-8876198|dip:DIP-42002N intact:EBI-7089968(isoform-parent)|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript) psi-mi:"MI:0465"(dip) comment:mint|function:May be involved in vesicular trafficking and neurotransmitter release - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:ucWVK9e1z44F2XnAJatPYm8IRlk9615 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rigid:DXz5PD3kW7/acO6P/FlcSYfT0Us false mutation increasing interaction strength:22-22|flag tag:n-n green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)