#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q24592	uniprotkb:P11147	intact:EBI-521224|uniprotkb:Q712V3|uniprotkb:Q8SZI9|uniprotkb:Q9VYZ7|ensemblmetazoa:FBpp0073313	intact:EBI-75181|uniprotkb:Q3KN45|uniprotkb:Q8SXQ4|uniprotkb:Q9VFB0|ensemblmetazoa:FBpp0082514|ensemblmetazoa:FBpp0082515|ensemblmetazoa:FBpp0082516|ensemblmetazoa:FBpp0082517|ensemblmetazoa:FBpp0082518|ensemblmetazoa:FBpp0082519|ensemblmetazoa:FBpp0307982	psi-mi:jak_drome(display_long)|uniprotkb:hop(gene name)|psi-mi:hop(display_short)|uniprotkb:HD-160(gene name synonym)|uniprotkb:CG1594(orf name)	psi-mi:hsp7d_drome(display_long)|uniprotkb:Hsc70-4(gene name)|psi-mi:Hsc70-4(display_short)|uniprotkb:Hsc4(gene name synonym)|uniprotkb:CG4264(orf name)|uniprotkb:Heat shock 70 kDa protein 88E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Iwasaki et al. (2015)	pubmed:25822791|doi:10.1038/nature14254|imex:IM-24577	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16151646|imex:IM-24577-1|dip:DIP-199257E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_511119.2|flybase:FBgn0004864|dip:DIP-61595N|ensemblmetazoa:FBgn0004864(gene)|ensemblmetazoa:FBtr0073457(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007365"(periodic partitioning)|go:"GO:0007399"(nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0007481"(haltere disc morphogenesis)|go:"GO:0007538"(primary sex determination)|go:"GO:0007616"(long-term memory)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0042386"(hemocyte differentiation)|go:"GO:0045317"(equator specification)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0048749"(compound eye development)|go:"GO:0051607"(defense response to virus)|go:"GO:0060031"(mediolateral intercalation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR036860|reactome:R-DME-1266695|reactome:R-DME-1433557|reactome:R-DME-209209|reactome:R-DME-209228|reactome:R-DME-210688|reactome:R-DME-5673000|reactome:R-DME-6785807|reactome:R-DME-69231|reactome:R-DME-8985947|reactome:R-DME-9020558|reactome:R-DME-9027276|reactome:R-DME-9027284	refseq:NP_524356.1|refseq:NP_731987.1|refseq:NP_731988.1|refseq:NP_731989.1|refseq:NP_788679.1|refseq:NP_788680.1|flybase:FBgn0266599|refseq:NP_001262586.1|dip:DIP-19158N|ensemblmetazoa:FBgn0266599(gene)|ensemblmetazoa:FBtr0083055(transcript)|ensemblmetazoa:FBtr0083056(transcript)|ensemblmetazoa:FBtr0083057(transcript)|ensemblmetazoa:FBtr0083058(transcript)|ensemblmetazoa:FBtr0083059(transcript)|ensemblmetazoa:FBtr0083060(transcript)|ensemblmetazoa:FBtr0337053(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016246"(RNA interference)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0035967"(cellular response to topologically incorrect protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097753"(membrane bending)|go:"GO:0098793"(presynapse)|go:"GO:0106161"(obsolete positive regulation of small RNA loading onto RISC)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11147|reactome:R-DME-3371453|reactome:R-DME-3371497|reactome:R-DME-3371571|reactome:R-DME-450408|reactome:R-DME-6798695|reactome:R-DME-72163|reactome:R-DME-8856828|reactome:R-DME-888590	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/08	2017/08/10	rogid:3LpEsspOZyEaY6hDP/uKjAlBqZo7227	rogid:0e7AjwNXSuekfdcT63i3/qeJ5ww7227	rigid:YKn9dByaTcxlphh/WeKmeRfKcyA	false	sbp:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q24592	uniprotkb:P02828	intact:EBI-521224|uniprotkb:Q712V3|uniprotkb:Q8SZI9|uniprotkb:Q9VYZ7|ensemblmetazoa:FBpp0073313	intact:EBI-136814|ensemblmetazoa:FBpp0072904|ensemblmetazoa:FBpp0305095|uniprotkb:P92174|uniprotkb:P92202|uniprotkb:Q9VZT3	psi-mi:jak_drome(display_long)|uniprotkb:hop(gene name)|psi-mi:hop(display_short)|uniprotkb:HD-160(gene name synonym)|uniprotkb:CG1594(orf name)	psi-mi:hsp83_drome(display_long)|uniprotkb:Hsp83(gene name)|psi-mi:Hsp83(display_short)|uniprotkb:Hsp82(gene name synonym)|uniprotkb:HSP 82(gene name synonym)|uniprotkb:Hsp90(gene name synonym)|uniprotkb:CG1242(orf name)	psi-mi:"MI:0096"(pull down)	Iwasaki et al. (2015)	pubmed:25822791|doi:10.1038/nature14254|imex:IM-24577	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16151646|imex:IM-24577-1|dip:DIP-199257E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_511119.2|flybase:FBgn0004864|dip:DIP-61595N|ensemblmetazoa:FBgn0004864(gene)|ensemblmetazoa:FBtr0073457(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0007365"(periodic partitioning)|go:"GO:0007399"(nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0007481"(haltere disc morphogenesis)|go:"GO:0007538"(primary sex determination)|go:"GO:0007616"(long-term memory)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0042386"(hemocyte differentiation)|go:"GO:0045317"(equator specification)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0048749"(compound eye development)|go:"GO:0051607"(defense response to virus)|go:"GO:0060031"(mediolateral intercalation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR036860|reactome:R-DME-1266695|reactome:R-DME-1433557|reactome:R-DME-209209|reactome:R-DME-209228|reactome:R-DME-210688|reactome:R-DME-5673000|reactome:R-DME-6785807|reactome:R-DME-69231|reactome:R-DME-8985947|reactome:R-DME-9020558|reactome:R-DME-9027276|reactome:R-DME-9027284	go:"GO:0005158"(insulin receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|ensemblmetazoa:FBgn0001233(gene)|ensemblmetazoa:FBtr0073040(transcript)|ensemblmetazoa:FBtr0332873(transcript)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0009631"(cold acclimation)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0019094"(pole plasm mRNA localization)|go:"GO:0030911"(TPR domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0101031"(chaperone complex)|go:"GO:0106161"(obsolete positive regulation of small RNA loading onto RISC)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|reactome:R-DME-1227986|reactome:R-DME-1474151|reactome:R-DME-2029482|reactome:R-DME-203615|reactome:R-DME-3371497|reactome:R-DME-3371511|refseq:NP_523899.1|flybase:FBgn0001233|refseq:NP_001261362.1|go:"GO:0043248"(proteasome assembly)|dip:DIP-17366N|reactome:R-DME-399954|reactome:R-DME-5218920|reactome:R-DME-5675482|reactome:R-DME-6798695|reactome:R-DME-3371571|reactome:R-DME-8863795|reactome:R-DME-8937144|reactome:R-DME-8939211|reactome:R-DME-9009391|reactome:R-DME-9013418|reactome:R-DME-9652282	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/08	2017/08/10	rogid:3LpEsspOZyEaY6hDP/uKjAlBqZo7227	rogid:PS2fd2RD7YWygzaMqF40SNCb2xQ7227	rigid:YKn9dByaTcxlphh/WeKmeRfKcyA	false	sbp:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)