#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q16656	uniprotkb:Q9NRC8	intact:EBI-2547810|ensembl:ENSP00000223190|ensembl:ENSP00000376922|ensembl:ENSP00000376924|uniprotkb:Q15305|uniprotkb:A8K4C6|uniprotkb:B4DDV6|uniprotkb:Q96AN2	intact:EBI-716046|uniprotkb:Q3MIK4|uniprotkb:Q9NSZ6|uniprotkb:Q9NUS6|uniprotkb:A8K2K0|uniprotkb:B3KSU8|ensembl:ENSP00000329466	psi-mi:nrf1_human(display_long)|uniprotkb:NRF1(gene name)|psi-mi:NRF1(display_short)|uniprotkb:Alpha palindromic-binding protein(gene name synonym)	psi-mi:sir7_human(display_long)|uniprotkb:NAD-dependent protein deacylase sirtuin-7(gene name synonym)|uniprotkb:SIR2-like protein 7(gene name synonym)|uniprotkb:SIRT7(gene name)|psi-mi:SIRT7(display_short)|uniprotkb:SIR2L7(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mohrin et al. (2015)	pubmed:25792330|doi:10.1126/science.aaa2361|imex:IM-24339	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16150178|imex:IM-24339-1|dip:DIP-198970E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000106459(gene)|ensembl:ENST00000223190(transcript)|ensembl:ENST00000393230(transcript)|ensembl:ENST00000393232(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070062"(extracellular exosome)|interpro:IPR019525|interpro:IPR019526|interpro:IPR039142|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0005634"(nucleus)|refseq:NP_001280092.1|refseq:NP_001280093.1|refseq:NP_001035199.1|refseq:NP_005002.3|dip:DIP-56958N	refseq:NP_057622.1|ensembl:ENSG00000187531(gene)|ensembl:ENST00000328666(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005731"(nucleolus organizer region)|go:"GO:0005737"(cytoplasm)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007072"(positive regulation of transcription involved in exit from mitosis)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0009303"(rRNA transcription)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016570"(histone modification)|go:"GO:0016607"(nuclear speck)|go:"GO:0019213"(deacetylase activity)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036049"(peptidyl-lysine desuccinylation)|go:"GO:0036055"(protein-succinyllysine desuccinylase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0061697"(protein-glutaryllysine deglutarylase activity)|go:"GO:0061698"(protein deglutarylation)|go:"GO:0005730"(nucleolus)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097372"("NAD-dependent histone deacetylase activity (H3-K18 specific)")|go:"GO:0106230"(protein depropionylation)|go:"GO:0106231"(protein-propionyllysine depropionylase activity)|go:"GO:1901836"(regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:2000234"(positive regulation of rRNA processing)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:5IQZ|rcsb pdb:6G0S|go:"GO:0062176"(R-loop disassembly)|dip:DIP-59906N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:QvOptENwVbP2E1Z8ExTOmbx00NE9606	rogid:MQgoNlLFPQ+zjXqF+ROIRzO5w+w9606	rigid:IFBJA36gT1zXJzK9lR4kfx1ujv0	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q16656	uniprotkb:Q9NRC8	intact:EBI-2547810|ensembl:ENSP00000223190|ensembl:ENSP00000376922|ensembl:ENSP00000376924|uniprotkb:Q15305|uniprotkb:A8K4C6|uniprotkb:B4DDV6|uniprotkb:Q96AN2	intact:EBI-716046|uniprotkb:Q3MIK4|uniprotkb:Q9NSZ6|uniprotkb:Q9NUS6|uniprotkb:A8K2K0|uniprotkb:B3KSU8|ensembl:ENSP00000329466	psi-mi:nrf1_human(display_long)|uniprotkb:NRF1(gene name)|psi-mi:NRF1(display_short)|uniprotkb:Alpha palindromic-binding protein(gene name synonym)	psi-mi:sir7_human(display_long)|uniprotkb:NAD-dependent protein deacylase sirtuin-7(gene name synonym)|uniprotkb:SIR2-like protein 7(gene name synonym)|uniprotkb:SIRT7(gene name)|psi-mi:SIRT7(display_short)|uniprotkb:SIR2L7(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohrin et al. (2015)	pubmed:25792330|doi:10.1126/science.aaa2361|imex:IM-24339	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16150197|imex:IM-24339-2|dip:DIP-198970E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000106459(gene)|ensembl:ENST00000223190(transcript)|ensembl:ENST00000393230(transcript)|ensembl:ENST00000393232(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070062"(extracellular exosome)|interpro:IPR019525|interpro:IPR019526|interpro:IPR039142|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0005634"(nucleus)|refseq:NP_001280092.1|refseq:NP_001280093.1|refseq:NP_001035199.1|refseq:NP_005002.3|dip:DIP-56958N	refseq:NP_057622.1|ensembl:ENSG00000187531(gene)|ensembl:ENST00000328666(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005731"(nucleolus organizer region)|go:"GO:0005737"(cytoplasm)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007072"(positive regulation of transcription involved in exit from mitosis)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0009303"(rRNA transcription)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016570"(histone modification)|go:"GO:0016607"(nuclear speck)|go:"GO:0019213"(deacetylase activity)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036049"(peptidyl-lysine desuccinylation)|go:"GO:0036055"(protein-succinyllysine desuccinylase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0061697"(protein-glutaryllysine deglutarylase activity)|go:"GO:0061698"(protein deglutarylation)|go:"GO:0005730"(nucleolus)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097372"("NAD-dependent histone deacetylase activity (H3-K18 specific)")|go:"GO:0106230"(protein depropionylation)|go:"GO:0106231"(protein-propionyllysine depropionylase activity)|go:"GO:1901836"(regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:2000234"(positive regulation of rRNA processing)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:5IQZ|rcsb pdb:6G0S|go:"GO:0062176"(R-loop disassembly)|dip:DIP-59906N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:QvOptENwVbP2E1Z8ExTOmbx00NE9606	rogid:MQgoNlLFPQ+zjXqF+ROIRzO5w+w9606	rigid:IFBJA36gT1zXJzK9lR4kfx1ujv0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)