#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P38632	uniprotkb:Q08204	intact:EBI-11017|ensemblfungi:YEL019C|uniprotkb:D3DLN0	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	psi-mi:nse2_yeast(display_long)|uniprotkb:MMS21(gene name)|psi-mi:MMS21(display_short)|uniprotkb:Methyl methanesulfonate-sensitivity protein 21(gene name synonym)|uniprotkb:Non-structural maintenance of chromosome element 2(gene name synonym)|uniprotkb:E3 SUMO-protein transferase MMS21(gene name synonym)|uniprotkb:NSE2(gene name synonym)|uniprotkb:YEL019C(locus name)	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bermúdez-López et al. (2015)	pubmed:25764370|doi:10.1371/journal.pbio.1002089|imex:IM-24226	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16149327|imex:IM-24226-2|dip:DIP-151062E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YEL019C(gene)|ensemblfungi:YEL019C_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR026846|rcsb pdb:3HTK|reactome:R-SCE-3108214|refseq:NP_010896.3|sgd:S000000745|mint:P38632|dip:DIP-4100N	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214	psi-mi:"MI:0465"(dip)	crc64:F200378289B1CEE4	crc64:6752B96438CFB549	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:pb9tvvMlnpncucC+DpK+SruIfAs559292	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	rigid:dI8a5BHYM5OaB0JcbOJz6YiDweI	false	ha tag:c-c	mutation disrupting interaction strength:791-791,787-787,784-784,780-780|mutation decreasing interaction strength:762-762,755-755,752-752|myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38632	uniprotkb:Q08204	intact:EBI-11017|ensemblfungi:YEL019C|uniprotkb:D3DLN0	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	psi-mi:nse2_yeast(display_long)|uniprotkb:MMS21(gene name)|psi-mi:MMS21(display_short)|uniprotkb:Methyl methanesulfonate-sensitivity protein 21(gene name synonym)|uniprotkb:Non-structural maintenance of chromosome element 2(gene name synonym)|uniprotkb:E3 SUMO-protein transferase MMS21(gene name synonym)|uniprotkb:NSE2(gene name synonym)|uniprotkb:YEL019C(locus name)	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:"MI:0071"(molecular sieving)	Bermúdez-López et al. (2015)	pubmed:25764370|doi:10.1371/journal.pbio.1002089|imex:IM-24226	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16149310|imex:IM-24226-1|dip:DIP-151062E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YEL019C(gene)|ensemblfungi:YEL019C_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR026846|rcsb pdb:3HTK|reactome:R-SCE-3108214|refseq:NP_010896.3|sgd:S000000745|mint:P38632|dip:DIP-4100N	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214	psi-mi:"MI:0465"(dip)	crc64:F200378289B1CEE4	crc64:6752B96438CFB549	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:pb9tvvMlnpncucC+DpK+SruIfAs559292	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	rigid:dI8a5BHYM5OaB0JcbOJz6YiDweI	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q12306	uniprotkb:Q08204	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:"MI:0096"(pull down)	Bermúdez-López et al. (2015)	pubmed:25764370|doi:10.1371/journal.pbio.1002089|imex:IM-24226	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16149526|imex:IM-24226-10|dip:DIP-198763E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214	psi-mi:"MI:0465"(dip)	crc64:A2790DE7F315E1A7	crc64:6752B96438CFB549	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	rigid:Ku1rRX4682XodAcKyKTJvq9piNo	false	his tag:n-n	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q12306	uniprotkb:P32908	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bermúdez-López et al. (2015)	pubmed:25764370|doi:10.1371/journal.pbio.1002089|imex:IM-24226	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16149526|imex:IM-24226-10|dip:DIP-198763E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306	refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N	psi-mi:"MI:0465"(dip)	crc64:A2790DE7F315E1A7	crc64:B504017AA0ECCA8C	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292	rigid:Ku1rRX4682XodAcKyKTJvq9piNo	false	his tag:n-n	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P43124	uniprotkb:Q08204	intact:EBI-14410|uniprotkb:D6VRP5|ensemblfungi:YDL105W	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	psi-mi:nse4_yeast(display_long)|uniprotkb:NSE4(gene name)|psi-mi:NSE4(display_short)|uniprotkb:YDL105W(locus name)|uniprotkb:D2354(orf name)|uniprotkb:QRI2(gene name synonym)|uniprotkb:Protein QRI2(gene name synonym)	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bermúdez-López et al. (2015)	pubmed:25764370|doi:10.1371/journal.pbio.1002089|imex:IM-24226	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16149421|imex:IM-24226-6|dip:DIP-138379E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010178.1|sgd:S000002263|interpro:IPR014854(Nse4)|interpro:IPR027786|interpro:IPR029225|reactome:R-SCE-3108214|go:"GO:0030915"(Smc5-Smc6 complex)|ensemblfungi:YDL105W(gene)|ensemblfungi:YDL105W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0016925"(protein sumoylation)|mint:P43124|dip:DIP-2839N	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214	psi-mi:"MI:0465"(dip)	crc64:503FD4614C01CD51	crc64:6752B96438CFB549	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:vUBJ9YGtOXag8GZOVV5/NhtRDNI559292	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	rigid:vpnDUhPB8WYbP3VmXpylja1FUoQ	false	ha tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P43124	uniprotkb:Q12306	intact:EBI-14410|uniprotkb:D6VRP5|ensemblfungi:YDL105W	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:nse4_yeast(display_long)|uniprotkb:NSE4(gene name)|psi-mi:NSE4(display_short)|uniprotkb:YDL105W(locus name)|uniprotkb:D2354(orf name)|uniprotkb:QRI2(gene name synonym)|uniprotkb:Protein QRI2(gene name synonym)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:0096"(pull down)	Bermúdez-López et al. (2015)	pubmed:25764370|doi:10.1371/journal.pbio.1002089|imex:IM-24226	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16149442|imex:IM-24226-7|dip:DIP-198762E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010178.1|sgd:S000002263|interpro:IPR014854(Nse4)|interpro:IPR027786|interpro:IPR029225|reactome:R-SCE-3108214|go:"GO:0030915"(Smc5-Smc6 complex)|ensemblfungi:YDL105W(gene)|ensemblfungi:YDL105W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0016925"(protein sumoylation)|mint:P43124|dip:DIP-2839N	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306	psi-mi:"MI:0465"(dip)	crc64:503FD4614C01CD51	crc64:A2790DE7F315E1A7	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:vUBJ9YGtOXag8GZOVV5/NhtRDNI559292	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	rigid:LQUY71So79FRJ7BVYTpyHoZ2Fts	false	ha tag:c-c	his tag:n-n|flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q12306	uniprotkb:Q08204	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:"MI:0096"(pull down)	Bermúdez-López et al. (2015)	pubmed:25764370|doi:10.1371/journal.pbio.1002089|imex:IM-24226	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16149466|imex:IM-24226-8|dip:DIP-104241E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214	psi-mi:"MI:0465"(dip)	crc64:A2790DE7F315E1A7	crc64:6752B96438CFB549	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	rigid:HEQ/mNOMmHYp7oQkmyJFFeXn/SI	false	his tag:n-n|flag tag:n-n	mutation disrupting interaction strength:791-791,787-787,784-784,780-780|mutation decreasing interaction strength:762-762,755-755,752-752|myc tag:c-c|mutation decreasing interaction strength:773-773,769-769	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38632	uniprotkb:Q08204	intact:EBI-11017|ensemblfungi:YEL019C|uniprotkb:D3DLN0	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	psi-mi:nse2_yeast(display_long)|uniprotkb:MMS21(gene name)|psi-mi:MMS21(display_short)|uniprotkb:Methyl methanesulfonate-sensitivity protein 21(gene name synonym)|uniprotkb:Non-structural maintenance of chromosome element 2(gene name synonym)|uniprotkb:E3 SUMO-protein transferase MMS21(gene name synonym)|uniprotkb:NSE2(gene name synonym)|uniprotkb:YEL019C(locus name)	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bermúdez-López et al. (2015)	pubmed:25764370|doi:10.1371/journal.pbio.1002089|imex:IM-24226	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16149505|imex:IM-24226-9|dip:DIP-151062E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YEL019C(gene)|ensemblfungi:YEL019C_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR026846|rcsb pdb:3HTK|reactome:R-SCE-3108214|refseq:NP_010896.3|sgd:S000000745|mint:P38632|dip:DIP-4100N	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214	psi-mi:"MI:0465"(dip)	crc64:F200378289B1CEE4	crc64:6752B96438CFB549	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:pb9tvvMlnpncucC+DpK+SruIfAs559292	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	rigid:dI8a5BHYM5OaB0JcbOJz6YiDweI	false	ha tag:c-c	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q12306	uniprotkb:Q08204	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:"MI:0096"(pull down)	Bermúdez-López et al. (2015)	pubmed:25764370|doi:10.1371/journal.pbio.1002089|imex:IM-24226	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16149380|imex:IM-24226-4|dip:DIP-104241E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214	psi-mi:"MI:0465"(dip)	crc64:A2790DE7F315E1A7	crc64:6752B96438CFB549	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	rigid:HEQ/mNOMmHYp7oQkmyJFFeXn/SI	false	his tag:n-n|flag tag:n-n	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q03718	uniprotkb:Q08204	intact:EBI-27756|uniprotkb:D6VZF1|ensemblfungi:YML023C	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	psi-mi:nse5_yeast(display_long)|uniprotkb:YML023C(locus name)|uniprotkb:NSE5(gene name)|psi-mi:NSE5(display_short)	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bermúdez-López et al. (2015)	pubmed:25764370|doi:10.1371/journal.pbio.1002089|imex:IM-24226	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16149359|imex:IM-24226-3|dip:DIP-167043E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013689.1|sgd:S000004485|dip:DIP-4547N|ensemblfungi:YML023C(gene)|ensemblfungi:YML023C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|interpro:IPR014803(DNA repair protein Nse5)|rcsb pdb:7LTO	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214	psi-mi:"MI:0465"(dip)	crc64:6680A04D91E537DD	crc64:6752B96438CFB549	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:xDmbHW4E/uX4NGGcDCMXTnUDQGk559292	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	rigid:Pd2GeW1d+smf0U6fQ3knyTndB1A	false	myc tag:c-c	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38632	uniprotkb:Q08204	intact:EBI-11017|ensemblfungi:YEL019C|uniprotkb:D3DLN0	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	psi-mi:nse2_yeast(display_long)|uniprotkb:MMS21(gene name)|psi-mi:MMS21(display_short)|uniprotkb:Methyl methanesulfonate-sensitivity protein 21(gene name synonym)|uniprotkb:Non-structural maintenance of chromosome element 2(gene name synonym)|uniprotkb:E3 SUMO-protein transferase MMS21(gene name synonym)|uniprotkb:NSE2(gene name synonym)|uniprotkb:YEL019C(locus name)	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:"MI:0872"(atomic force microscopy)	Bermúdez-López et al. (2015)	pubmed:25764370|doi:10.1371/journal.pbio.1002089|imex:IM-24226	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16149404|imex:IM-24226-5|dip:DIP-151062E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YEL019C(gene)|ensemblfungi:YEL019C_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR026846|rcsb pdb:3HTK|reactome:R-SCE-3108214|refseq:NP_010896.3|sgd:S000000745|mint:P38632|dip:DIP-4100N	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214	psi-mi:"MI:0465"(dip)	crc64:F200378289B1CEE4	crc64:6752B96438CFB549	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:pb9tvvMlnpncucC+DpK+SruIfAs559292	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	rigid:dI8a5BHYM5OaB0JcbOJz6YiDweI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q05541	uniprotkb:Q08204	intact:EBI-36625|uniprotkb:D6VSR8|ensemblfungi:YDR288W	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	psi-mi:nse3_yeast(display_long)|uniprotkb:NSE3(gene name)|psi-mi:NSE3(display_short)|uniprotkb:YDR288W(locus name)	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bermúdez-López et al. (2015)	pubmed:25764370|doi:10.1371/journal.pbio.1002089|imex:IM-24226	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16149574|imex:IM-24226-12|dip:DIP-149595E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010574.1|sgd:S000002696|mint:Q05541|dip:DIP-2838N|ensemblfungi:YDR288W(gene)|ensemblfungi:YDR288W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|interpro:IPR002190(MAGE protein)|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|reactome:R-SCE-114608|reactome:R-SCE-3108214	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214	psi-mi:"MI:0465"(dip)	crc64:A750A9E31F80D8D1	crc64:6752B96438CFB549	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:0Ji2fJPx/dfaIMW7APXtPQLDzKM559292	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	rigid:re08QZpysgf2CCmFebrosgM3Zus	false	myc tag:c-c	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P43124	uniprotkb:Q12306	intact:EBI-14410|uniprotkb:D6VRP5|ensemblfungi:YDL105W	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:nse4_yeast(display_long)|uniprotkb:NSE4(gene name)|psi-mi:NSE4(display_short)|uniprotkb:YDL105W(locus name)|uniprotkb:D2354(orf name)|uniprotkb:QRI2(gene name synonym)|uniprotkb:Protein QRI2(gene name synonym)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:0096"(pull down)	Bermúdez-López et al. (2015)	pubmed:25764370|doi:10.1371/journal.pbio.1002089|imex:IM-24226	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16149550|imex:IM-24226-11|dip:DIP-198762E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010178.1|sgd:S000002263|interpro:IPR014854(Nse4)|interpro:IPR027786|interpro:IPR029225|reactome:R-SCE-3108214|go:"GO:0030915"(Smc5-Smc6 complex)|ensemblfungi:YDL105W(gene)|ensemblfungi:YDL105W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0016925"(protein sumoylation)|mint:P43124|dip:DIP-2839N	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306	psi-mi:"MI:0465"(dip)	crc64:503FD4614C01CD51	crc64:A2790DE7F315E1A7	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:vUBJ9YGtOXag8GZOVV5/NhtRDNI559292	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	rigid:LQUY71So79FRJ7BVYTpyHoZ2Fts	false	myc tag:c-c	his tag:n-n|flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32908	uniprotkb:Q12306	intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:0096"(pull down)	Bermúdez-López et al. (2015)	pubmed:25764370|doi:10.1371/journal.pbio.1002089|imex:IM-24226	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16149595|imex:IM-24226-13|dip:DIP-198761E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306	psi-mi:"MI:0465"(dip)	crc64:B504017AA0ECCA8C	crc64:A2790DE7F315E1A7	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	rigid:awKlSIDIl1X6meH1midoBJg03PE	false	ha tag:c-c	his tag:n-n|flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)