#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O16810 uniprotkb:Q24168 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-179453|intact:EBI-1631787|uniprotkb:Q9VFP4|ensemblmetazoa:FBpp0082329 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:orc2_drome(display_long)|uniprotkb:Orc2(gene name)|psi-mi:Orc2(display_short)|uniprotkb:CG3041(orf name) psi-mi:"MI:0114"(x-ray crystallography) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16148863|imex:IM-24404-1|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_731873.1|flybase:FBgn0015270|dip:DIP-23209N|ensemblmetazoa:FBgn0015270(gene)|ensemblmetazoa:FBtr0082866(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005723"(alpha-heterochromatin)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0030261"(chromosome condensation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:SaBA2xfoQcWtCiLhN6rD5O5yMhg7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924 sufficient binding region:266-618 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q24169 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-137663|uniprotkb:Q9V398|ensemblmetazoa:FBpp0080120 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:orc5_drome(display_long)|uniprotkb:Orc5(gene name)|psi-mi:Orc5(display_short)|uniprotkb:CG7833(orf name) psi-mi:"MI:0114"(x-ray crystallography) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16148863|imex:IM-24404-1|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_477132.1|flybase:FBgn0015271|dip:DIP-49320N|ensemblmetazoa:FBgn0015271(gene)|ensemblmetazoa:FBtr0080543(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:z+aa5qCMIPJJqDorJu/xRjCValE7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q9Y1B2 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-113296|uniprotkb:Q9V5C5|ensemblmetazoa:FBpp0087566 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:orc6_drome(display_long)|uniprotkb:Orc6(gene name)|psi-mi:Orc6(display_short)|uniprotkb:CG1584(orf name) psi-mi:"MI:0114"(x-ray crystallography) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16148863|imex:IM-24404-1|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_477319.1|flybase:FBgn0023180|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|ensemblmetazoa:FBgn0023180(gene)|ensemblmetazoa:FBtr0088482(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000808"(origin recognition complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR020529|rcsb pdb:4XGC|rcsb pdb:7JGR|dip:DIP-49258N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:1l2xkmHWJBVXCc+nGLx6RpjMec07227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924 sufficient binding region:187-257 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q7K2L1 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-182021|ensemblmetazoa:FBpp0086881|ensemblmetazoa:FBpp0086882 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:q7k2l1_drome(display_long)|uniprotkb:Orc3(gene name)|psi-mi:Orc3(display_short)|uniprotkb:CG34315-RB(gene name synonym)|uniprotkb:lat(gene name synonym)|uniprotkb:lat-RA(gene name synonym)|uniprotkb:DmORC3(gene name synonym)|uniprotkb:DmOrc3(gene name synonym)|uniprotkb:Dmel\CG4088(gene name synonym)|uniprotkb:LAT(gene name synonym)|uniprotkb:Lat(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC3(gene name synonym)|uniprotkb:"l(2)49Fd"(gene name synonym)|uniprotkb:"l(2)vr6"(gene name synonym)|uniprotkb:latheo(gene name synonym)|uniprotkb:orc3(gene name synonym)|uniprotkb:vr-6(gene name synonym)|uniprotkb:vr6(gene name synonym)|uniprotkb:CG4088(orf name)|uniprotkb:Dmel_CG4088(orf name) psi-mi:"MI:0114"(x-ray crystallography) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16148863|imex:IM-24404-1|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_476904.1|flybase:FBgn0005654|refseq:NP_725260.1|dip:DIP-61503N|ensemblmetazoa:FBgn0005654(gene)|ensemblmetazoa:FBtr0087768(transcript)|ensemblmetazoa:FBtr0087769(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0008355"(olfactory learning)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR020795|interpro:IPR040855|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:vnTqJ3kfCs01ajCEbIp8u6K8NkQ7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924 sufficient binding region:47-721 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q9W102 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-156676|ensemblmetazoa:FBpp0072330 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:"MI:0114"(x-ray crystallography) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16148863|imex:IM-24404-1|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q9Y1B2 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-113296|uniprotkb:Q9V5C5|ensemblmetazoa:FBpp0087566 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:orc6_drome(display_long)|uniprotkb:Orc6(gene name)|psi-mi:Orc6(display_short)|uniprotkb:CG1584(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16148921|imex:IM-24404-3|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_477319.1|flybase:FBgn0023180|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|ensemblmetazoa:FBgn0023180(gene)|ensemblmetazoa:FBtr0088482(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000808"(origin recognition complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR020529|rcsb pdb:4XGC|rcsb pdb:7JGR|dip:DIP-49258N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:1l2xkmHWJBVXCc+nGLx6RpjMec07227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924|his tag:n-n sufficient binding region:187-257 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q24169 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-137663|uniprotkb:Q9V398|ensemblmetazoa:FBpp0080120 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:orc5_drome(display_long)|uniprotkb:Orc5(gene name)|psi-mi:Orc5(display_short)|uniprotkb:CG7833(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16148921|imex:IM-24404-3|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_477132.1|flybase:FBgn0015271|dip:DIP-49320N|ensemblmetazoa:FBgn0015271(gene)|ensemblmetazoa:FBtr0080543(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:z+aa5qCMIPJJqDorJu/xRjCValE7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924|his tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q9W102 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-156676|ensemblmetazoa:FBpp0072330 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16148921|imex:IM-24404-3|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924|his tag:n-n maltose binding protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q7K2L1 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-182021|ensemblmetazoa:FBpp0086881|ensemblmetazoa:FBpp0086882 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:q7k2l1_drome(display_long)|uniprotkb:Orc3(gene name)|psi-mi:Orc3(display_short)|uniprotkb:CG34315-RB(gene name synonym)|uniprotkb:lat(gene name synonym)|uniprotkb:lat-RA(gene name synonym)|uniprotkb:DmORC3(gene name synonym)|uniprotkb:DmOrc3(gene name synonym)|uniprotkb:Dmel\CG4088(gene name synonym)|uniprotkb:LAT(gene name synonym)|uniprotkb:Lat(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC3(gene name synonym)|uniprotkb:"l(2)49Fd"(gene name synonym)|uniprotkb:"l(2)vr6"(gene name synonym)|uniprotkb:latheo(gene name synonym)|uniprotkb:orc3(gene name synonym)|uniprotkb:vr-6(gene name synonym)|uniprotkb:vr6(gene name synonym)|uniprotkb:CG4088(orf name)|uniprotkb:Dmel_CG4088(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16148921|imex:IM-24404-3|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_476904.1|flybase:FBgn0005654|refseq:NP_725260.1|dip:DIP-61503N|ensemblmetazoa:FBgn0005654(gene)|ensemblmetazoa:FBtr0087768(transcript)|ensemblmetazoa:FBtr0087769(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0008355"(olfactory learning)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR020795|interpro:IPR040855|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:vnTqJ3kfCs01ajCEbIp8u6K8NkQ7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924|his tag:n-n sufficient binding region:47-721 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q24168 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-179453|intact:EBI-1631787|uniprotkb:Q9VFP4|ensemblmetazoa:FBpp0082329 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:orc2_drome(display_long)|uniprotkb:Orc2(gene name)|psi-mi:Orc2(display_short)|uniprotkb:CG3041(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16148921|imex:IM-24404-3|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_731873.1|flybase:FBgn0015270|dip:DIP-23209N|ensemblmetazoa:FBgn0015270(gene)|ensemblmetazoa:FBtr0082866(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005723"(alpha-heterochromatin)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0030261"(chromosome condensation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:SaBA2xfoQcWtCiLhN6rD5O5yMhg7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924|his tag:n-n sufficient binding region:266-618 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q24168 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-179453|intact:EBI-1631787|uniprotkb:Q9VFP4|ensemblmetazoa:FBpp0082329 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:orc2_drome(display_long)|uniprotkb:Orc2(gene name)|psi-mi:Orc2(display_short)|uniprotkb:CG3041(orf name) psi-mi:"MI:0071"(molecular sieving) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16148892|imex:IM-24404-2|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_731873.1|flybase:FBgn0015270|dip:DIP-23209N|ensemblmetazoa:FBgn0015270(gene)|ensemblmetazoa:FBtr0082866(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005723"(alpha-heterochromatin)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0030261"(chromosome condensation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:SaBA2xfoQcWtCiLhN6rD5O5yMhg7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924 sufficient binding region:266-618 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q24169 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-137663|uniprotkb:Q9V398|ensemblmetazoa:FBpp0080120 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:orc5_drome(display_long)|uniprotkb:Orc5(gene name)|psi-mi:Orc5(display_short)|uniprotkb:CG7833(orf name) psi-mi:"MI:0071"(molecular sieving) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16148892|imex:IM-24404-2|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_477132.1|flybase:FBgn0015271|dip:DIP-49320N|ensemblmetazoa:FBgn0015271(gene)|ensemblmetazoa:FBtr0080543(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:z+aa5qCMIPJJqDorJu/xRjCValE7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q9Y1B2 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-113296|uniprotkb:Q9V5C5|ensemblmetazoa:FBpp0087566 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:orc6_drome(display_long)|uniprotkb:Orc6(gene name)|psi-mi:Orc6(display_short)|uniprotkb:CG1584(orf name) psi-mi:"MI:0071"(molecular sieving) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16148892|imex:IM-24404-2|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_477319.1|flybase:FBgn0023180|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|ensemblmetazoa:FBgn0023180(gene)|ensemblmetazoa:FBtr0088482(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000808"(origin recognition complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR020529|rcsb pdb:4XGC|rcsb pdb:7JGR|dip:DIP-49258N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:1l2xkmHWJBVXCc+nGLx6RpjMec07227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924 sufficient binding region:187-257 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q7K2L1 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-182021|ensemblmetazoa:FBpp0086881|ensemblmetazoa:FBpp0086882 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:q7k2l1_drome(display_long)|uniprotkb:Orc3(gene name)|psi-mi:Orc3(display_short)|uniprotkb:CG34315-RB(gene name synonym)|uniprotkb:lat(gene name synonym)|uniprotkb:lat-RA(gene name synonym)|uniprotkb:DmORC3(gene name synonym)|uniprotkb:DmOrc3(gene name synonym)|uniprotkb:Dmel\CG4088(gene name synonym)|uniprotkb:LAT(gene name synonym)|uniprotkb:Lat(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC3(gene name synonym)|uniprotkb:"l(2)49Fd"(gene name synonym)|uniprotkb:"l(2)vr6"(gene name synonym)|uniprotkb:latheo(gene name synonym)|uniprotkb:orc3(gene name synonym)|uniprotkb:vr-6(gene name synonym)|uniprotkb:vr6(gene name synonym)|uniprotkb:CG4088(orf name)|uniprotkb:Dmel_CG4088(orf name) psi-mi:"MI:0071"(molecular sieving) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16148892|imex:IM-24404-2|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_476904.1|flybase:FBgn0005654|refseq:NP_725260.1|dip:DIP-61503N|ensemblmetazoa:FBgn0005654(gene)|ensemblmetazoa:FBtr0087768(transcript)|ensemblmetazoa:FBtr0087769(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0008355"(olfactory learning)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR020795|interpro:IPR040855|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:vnTqJ3kfCs01ajCEbIp8u6K8NkQ7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924 sufficient binding region:47-721 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q9W102 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-156676|ensemblmetazoa:FBpp0072330 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:"MI:0071"(molecular sieving) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16148892|imex:IM-24404-2|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9W102 uniprotkb:Q24169 intact:EBI-156676|ensemblmetazoa:FBpp0072330 intact:EBI-137663|uniprotkb:Q9V398|ensemblmetazoa:FBpp0080120 psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:orc5_drome(display_long)|uniprotkb:Orc5(gene name)|psi-mi:Orc5(display_short)|uniprotkb:CG7833(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149031|imex:IM-24404-7|dip:DIP-199044E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 refseq:NP_477132.1|flybase:FBgn0015271|dip:DIP-49320N|ensemblmetazoa:FBgn0015271(gene)|ensemblmetazoa:FBtr0080543(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rogid:z+aa5qCMIPJJqDorJu/xRjCValE7227 rigid:41HRSibZ7HlrAVJrKPd7VxsTYCg false maltose binding protein tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9W102 uniprotkb:Q7K2L1 intact:EBI-156676|ensemblmetazoa:FBpp0072330 intact:EBI-182021|ensemblmetazoa:FBpp0086881|ensemblmetazoa:FBpp0086882 psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:q7k2l1_drome(display_long)|uniprotkb:Orc3(gene name)|psi-mi:Orc3(display_short)|uniprotkb:CG34315-RB(gene name synonym)|uniprotkb:lat(gene name synonym)|uniprotkb:lat-RA(gene name synonym)|uniprotkb:DmORC3(gene name synonym)|uniprotkb:DmOrc3(gene name synonym)|uniprotkb:Dmel\CG4088(gene name synonym)|uniprotkb:LAT(gene name synonym)|uniprotkb:Lat(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC3(gene name synonym)|uniprotkb:"l(2)49Fd"(gene name synonym)|uniprotkb:"l(2)vr6"(gene name synonym)|uniprotkb:latheo(gene name synonym)|uniprotkb:orc3(gene name synonym)|uniprotkb:vr-6(gene name synonym)|uniprotkb:vr6(gene name synonym)|uniprotkb:CG4088(orf name)|uniprotkb:Dmel_CG4088(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149031|imex:IM-24404-7|dip:DIP-199044E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 refseq:NP_476904.1|flybase:FBgn0005654|refseq:NP_725260.1|dip:DIP-61503N|ensemblmetazoa:FBgn0005654(gene)|ensemblmetazoa:FBtr0087768(transcript)|ensemblmetazoa:FBtr0087769(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0008355"(olfactory learning)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR020795|interpro:IPR040855|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rogid:vnTqJ3kfCs01ajCEbIp8u6K8NkQ7227 rigid:41HRSibZ7HlrAVJrKPd7VxsTYCg false maltose binding protein tag:n-n sufficient binding region:47-721 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9W102 uniprotkb:Q24168 intact:EBI-156676|ensemblmetazoa:FBpp0072330 intact:EBI-179453|intact:EBI-1631787|uniprotkb:Q9VFP4|ensemblmetazoa:FBpp0082329 psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:orc2_drome(display_long)|uniprotkb:Orc2(gene name)|psi-mi:Orc2(display_short)|uniprotkb:CG3041(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149031|imex:IM-24404-7|dip:DIP-199044E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 refseq:NP_731873.1|flybase:FBgn0015270|dip:DIP-23209N|ensemblmetazoa:FBgn0015270(gene)|ensemblmetazoa:FBtr0082866(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005723"(alpha-heterochromatin)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0030261"(chromosome condensation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rogid:SaBA2xfoQcWtCiLhN6rD5O5yMhg7227 rigid:41HRSibZ7HlrAVJrKPd7VxsTYCg false maltose binding protein tag:n-n sufficient binding region:266-618 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9W102 uniprotkb:O16810 intact:EBI-156676|ensemblmetazoa:FBpp0072330 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149031|imex:IM-24404-7|dip:DIP-199044E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rigid:41HRSibZ7HlrAVJrKPd7VxsTYCg false maltose binding protein tag:n-n sufficient binding region:533-924|his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9W102 uniprotkb:Q9Y1B2 intact:EBI-156676|ensemblmetazoa:FBpp0072330 intact:EBI-113296|uniprotkb:Q9V5C5|ensemblmetazoa:FBpp0087566 psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:orc6_drome(display_long)|uniprotkb:Orc6(gene name)|psi-mi:Orc6(display_short)|uniprotkb:CG1584(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149061|imex:IM-24404-8|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 refseq:NP_477319.1|flybase:FBgn0023180|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|ensemblmetazoa:FBgn0023180(gene)|ensemblmetazoa:FBtr0088482(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000808"(origin recognition complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR020529|rcsb pdb:4XGC|rcsb pdb:7JGR|dip:DIP-49258N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rogid:1l2xkmHWJBVXCc+nGLx6RpjMec07227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false maltose binding protein tag:n-n sufficient binding region:187-257 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9W102 uniprotkb:Q24169 intact:EBI-156676|ensemblmetazoa:FBpp0072330 intact:EBI-137663|uniprotkb:Q9V398|ensemblmetazoa:FBpp0080120 psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:orc5_drome(display_long)|uniprotkb:Orc5(gene name)|psi-mi:Orc5(display_short)|uniprotkb:CG7833(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149061|imex:IM-24404-8|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 refseq:NP_477132.1|flybase:FBgn0015271|dip:DIP-49320N|ensemblmetazoa:FBgn0015271(gene)|ensemblmetazoa:FBtr0080543(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rogid:z+aa5qCMIPJJqDorJu/xRjCValE7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false maltose binding protein tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9W102 uniprotkb:Q7K2L1 intact:EBI-156676|ensemblmetazoa:FBpp0072330 intact:EBI-182021|ensemblmetazoa:FBpp0086881|ensemblmetazoa:FBpp0086882 psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:q7k2l1_drome(display_long)|uniprotkb:Orc3(gene name)|psi-mi:Orc3(display_short)|uniprotkb:CG34315-RB(gene name synonym)|uniprotkb:lat(gene name synonym)|uniprotkb:lat-RA(gene name synonym)|uniprotkb:DmORC3(gene name synonym)|uniprotkb:DmOrc3(gene name synonym)|uniprotkb:Dmel\CG4088(gene name synonym)|uniprotkb:LAT(gene name synonym)|uniprotkb:Lat(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC3(gene name synonym)|uniprotkb:"l(2)49Fd"(gene name synonym)|uniprotkb:"l(2)vr6"(gene name synonym)|uniprotkb:latheo(gene name synonym)|uniprotkb:orc3(gene name synonym)|uniprotkb:vr-6(gene name synonym)|uniprotkb:vr6(gene name synonym)|uniprotkb:CG4088(orf name)|uniprotkb:Dmel_CG4088(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149061|imex:IM-24404-8|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 refseq:NP_476904.1|flybase:FBgn0005654|refseq:NP_725260.1|dip:DIP-61503N|ensemblmetazoa:FBgn0005654(gene)|ensemblmetazoa:FBtr0087768(transcript)|ensemblmetazoa:FBtr0087769(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0008355"(olfactory learning)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR020795|interpro:IPR040855|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rogid:vnTqJ3kfCs01ajCEbIp8u6K8NkQ7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false maltose binding protein tag:n-n sufficient binding region:47-721 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9W102 uniprotkb:Q24168 intact:EBI-156676|ensemblmetazoa:FBpp0072330 intact:EBI-179453|intact:EBI-1631787|uniprotkb:Q9VFP4|ensemblmetazoa:FBpp0082329 psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:orc2_drome(display_long)|uniprotkb:Orc2(gene name)|psi-mi:Orc2(display_short)|uniprotkb:CG3041(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149061|imex:IM-24404-8|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 refseq:NP_731873.1|flybase:FBgn0015270|dip:DIP-23209N|ensemblmetazoa:FBgn0015270(gene)|ensemblmetazoa:FBtr0082866(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005723"(alpha-heterochromatin)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0030261"(chromosome condensation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rogid:SaBA2xfoQcWtCiLhN6rD5O5yMhg7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false maltose binding protein tag:n-n sufficient binding region:266-618 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9W102 uniprotkb:O16810 intact:EBI-156676|ensemblmetazoa:FBpp0072330 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149061|imex:IM-24404-8|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false maltose binding protein tag:n-n sufficient binding region:533-924 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Y1B2 uniprotkb:Q7K2L1 intact:EBI-113296|uniprotkb:Q9V5C5|ensemblmetazoa:FBpp0087566 intact:EBI-182021|ensemblmetazoa:FBpp0086881|ensemblmetazoa:FBpp0086882 psi-mi:orc6_drome(display_long)|uniprotkb:Orc6(gene name)|psi-mi:Orc6(display_short)|uniprotkb:CG1584(orf name) psi-mi:q7k2l1_drome(display_long)|uniprotkb:Orc3(gene name)|psi-mi:Orc3(display_short)|uniprotkb:CG34315-RB(gene name synonym)|uniprotkb:lat(gene name synonym)|uniprotkb:lat-RA(gene name synonym)|uniprotkb:DmORC3(gene name synonym)|uniprotkb:DmOrc3(gene name synonym)|uniprotkb:Dmel\CG4088(gene name synonym)|uniprotkb:LAT(gene name synonym)|uniprotkb:Lat(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC3(gene name synonym)|uniprotkb:"l(2)49Fd"(gene name synonym)|uniprotkb:"l(2)vr6"(gene name synonym)|uniprotkb:latheo(gene name synonym)|uniprotkb:orc3(gene name synonym)|uniprotkb:vr-6(gene name synonym)|uniprotkb:vr6(gene name synonym)|uniprotkb:CG4088(orf name)|uniprotkb:Dmel_CG4088(orf name) psi-mi:"MI:0030"(cross-linking study) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16149092|imex:IM-24404-9|dip:DIP-199045E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477319.1|flybase:FBgn0023180|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|ensemblmetazoa:FBgn0023180(gene)|ensemblmetazoa:FBtr0088482(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000808"(origin recognition complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR020529|rcsb pdb:4XGC|rcsb pdb:7JGR|dip:DIP-49258N refseq:NP_476904.1|flybase:FBgn0005654|refseq:NP_725260.1|dip:DIP-61503N|ensemblmetazoa:FBgn0005654(gene)|ensemblmetazoa:FBtr0087768(transcript)|ensemblmetazoa:FBtr0087769(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0008355"(olfactory learning)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR020795|interpro:IPR040855|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:1l2xkmHWJBVXCc+nGLx6RpjMec07227 rogid:vnTqJ3kfCs01ajCEbIp8u6K8NkQ7227 rigid:icPBuLDnY+u0awj9q6Xd82BW39I false sufficient binding region:187-257|mutation:236-236 sufficient binding region:47-721 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q24168 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-179453|intact:EBI-1631787|uniprotkb:Q9VFP4|ensemblmetazoa:FBpp0082329 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:orc2_drome(display_long)|uniprotkb:Orc2(gene name)|psi-mi:Orc2(display_short)|uniprotkb:CG3041(orf name) psi-mi:"MI:0071"(molecular sieving) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16149116|imex:IM-24404-10|dip:DIP-199044E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_731873.1|flybase:FBgn0015270|dip:DIP-23209N|ensemblmetazoa:FBgn0015270(gene)|ensemblmetazoa:FBtr0082866(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005723"(alpha-heterochromatin)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0030261"(chromosome condensation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:SaBA2xfoQcWtCiLhN6rD5O5yMhg7227 rigid:41HRSibZ7HlrAVJrKPd7VxsTYCg false sufficient binding region:533-924 sufficient binding region:266-618 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q24169 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-137663|uniprotkb:Q9V398|ensemblmetazoa:FBpp0080120 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:orc5_drome(display_long)|uniprotkb:Orc5(gene name)|psi-mi:Orc5(display_short)|uniprotkb:CG7833(orf name) psi-mi:"MI:0071"(molecular sieving) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16149116|imex:IM-24404-10|dip:DIP-199044E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_477132.1|flybase:FBgn0015271|dip:DIP-49320N|ensemblmetazoa:FBgn0015271(gene)|ensemblmetazoa:FBtr0080543(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:z+aa5qCMIPJJqDorJu/xRjCValE7227 rigid:41HRSibZ7HlrAVJrKPd7VxsTYCg false sufficient binding region:533-924 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q7K2L1 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-182021|ensemblmetazoa:FBpp0086881|ensemblmetazoa:FBpp0086882 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:q7k2l1_drome(display_long)|uniprotkb:Orc3(gene name)|psi-mi:Orc3(display_short)|uniprotkb:CG34315-RB(gene name synonym)|uniprotkb:lat(gene name synonym)|uniprotkb:lat-RA(gene name synonym)|uniprotkb:DmORC3(gene name synonym)|uniprotkb:DmOrc3(gene name synonym)|uniprotkb:Dmel\CG4088(gene name synonym)|uniprotkb:LAT(gene name synonym)|uniprotkb:Lat(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC3(gene name synonym)|uniprotkb:"l(2)49Fd"(gene name synonym)|uniprotkb:"l(2)vr6"(gene name synonym)|uniprotkb:latheo(gene name synonym)|uniprotkb:orc3(gene name synonym)|uniprotkb:vr-6(gene name synonym)|uniprotkb:vr6(gene name synonym)|uniprotkb:CG4088(orf name)|uniprotkb:Dmel_CG4088(orf name) psi-mi:"MI:0071"(molecular sieving) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16149116|imex:IM-24404-10|dip:DIP-199044E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_476904.1|flybase:FBgn0005654|refseq:NP_725260.1|dip:DIP-61503N|ensemblmetazoa:FBgn0005654(gene)|ensemblmetazoa:FBtr0087768(transcript)|ensemblmetazoa:FBtr0087769(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0008355"(olfactory learning)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR020795|interpro:IPR040855|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:vnTqJ3kfCs01ajCEbIp8u6K8NkQ7227 rigid:41HRSibZ7HlrAVJrKPd7VxsTYCg false sufficient binding region:533-924 sufficient binding region:47-721 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q9W102 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-156676|ensemblmetazoa:FBpp0072330 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:"MI:0071"(molecular sieving) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16149116|imex:IM-24404-10|dip:DIP-199044E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rigid:41HRSibZ7HlrAVJrKPd7VxsTYCg false sufficient binding region:533-924 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q24169 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-137663|uniprotkb:Q9V398|ensemblmetazoa:FBpp0080120 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:orc5_drome(display_long)|uniprotkb:Orc5(gene name)|psi-mi:Orc5(display_short)|uniprotkb:CG7833(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149001|imex:IM-24404-6|dip:DIP-199044E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_477132.1|flybase:FBgn0015271|dip:DIP-49320N|ensemblmetazoa:FBgn0015271(gene)|ensemblmetazoa:FBtr0080543(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:z+aa5qCMIPJJqDorJu/xRjCValE7227 rigid:41HRSibZ7HlrAVJrKPd7VxsTYCg false sufficient binding region:533-924|his tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q9W102 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-156676|ensemblmetazoa:FBpp0072330 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149001|imex:IM-24404-6|dip:DIP-199044E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rigid:41HRSibZ7HlrAVJrKPd7VxsTYCg false sufficient binding region:533-924|his tag:n-n maltose binding protein tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q7K2L1 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-182021|ensemblmetazoa:FBpp0086881|ensemblmetazoa:FBpp0086882 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:q7k2l1_drome(display_long)|uniprotkb:Orc3(gene name)|psi-mi:Orc3(display_short)|uniprotkb:CG34315-RB(gene name synonym)|uniprotkb:lat(gene name synonym)|uniprotkb:lat-RA(gene name synonym)|uniprotkb:DmORC3(gene name synonym)|uniprotkb:DmOrc3(gene name synonym)|uniprotkb:Dmel\CG4088(gene name synonym)|uniprotkb:LAT(gene name synonym)|uniprotkb:Lat(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC3(gene name synonym)|uniprotkb:"l(2)49Fd"(gene name synonym)|uniprotkb:"l(2)vr6"(gene name synonym)|uniprotkb:latheo(gene name synonym)|uniprotkb:orc3(gene name synonym)|uniprotkb:vr-6(gene name synonym)|uniprotkb:vr6(gene name synonym)|uniprotkb:CG4088(orf name)|uniprotkb:Dmel_CG4088(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149001|imex:IM-24404-6|dip:DIP-199044E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_476904.1|flybase:FBgn0005654|refseq:NP_725260.1|dip:DIP-61503N|ensemblmetazoa:FBgn0005654(gene)|ensemblmetazoa:FBtr0087768(transcript)|ensemblmetazoa:FBtr0087769(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0008355"(olfactory learning)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR020795|interpro:IPR040855|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:vnTqJ3kfCs01ajCEbIp8u6K8NkQ7227 rigid:41HRSibZ7HlrAVJrKPd7VxsTYCg false sufficient binding region:533-924|his tag:n-n sufficient binding region:47-721 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q24168 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-179453|intact:EBI-1631787|uniprotkb:Q9VFP4|ensemblmetazoa:FBpp0082329 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:orc2_drome(display_long)|uniprotkb:Orc2(gene name)|psi-mi:Orc2(display_short)|uniprotkb:CG3041(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149001|imex:IM-24404-6|dip:DIP-199044E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_731873.1|flybase:FBgn0015270|dip:DIP-23209N|ensemblmetazoa:FBgn0015270(gene)|ensemblmetazoa:FBtr0082866(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005723"(alpha-heterochromatin)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0030261"(chromosome condensation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:SaBA2xfoQcWtCiLhN6rD5O5yMhg7227 rigid:41HRSibZ7HlrAVJrKPd7VxsTYCg false sufficient binding region:533-924|his tag:n-n sufficient binding region:266-618 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7K2L1 uniprotkb:Q7K2L1 intact:EBI-182021|ensemblmetazoa:FBpp0086881|ensemblmetazoa:FBpp0086882 intact:EBI-182021|ensemblmetazoa:FBpp0086881|ensemblmetazoa:FBpp0086882 psi-mi:q7k2l1_drome(display_long)|uniprotkb:Orc3(gene name)|psi-mi:Orc3(display_short)|uniprotkb:CG34315-RB(gene name synonym)|uniprotkb:lat(gene name synonym)|uniprotkb:lat-RA(gene name synonym)|uniprotkb:DmORC3(gene name synonym)|uniprotkb:DmOrc3(gene name synonym)|uniprotkb:Dmel\CG4088(gene name synonym)|uniprotkb:LAT(gene name synonym)|uniprotkb:Lat(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC3(gene name synonym)|uniprotkb:"l(2)49Fd"(gene name synonym)|uniprotkb:"l(2)vr6"(gene name synonym)|uniprotkb:latheo(gene name synonym)|uniprotkb:orc3(gene name synonym)|uniprotkb:vr-6(gene name synonym)|uniprotkb:vr6(gene name synonym)|uniprotkb:CG4088(orf name)|uniprotkb:Dmel_CG4088(orf name) psi-mi:q7k2l1_drome(display_long)|uniprotkb:Orc3(gene name)|psi-mi:Orc3(display_short)|uniprotkb:CG34315-RB(gene name synonym)|uniprotkb:lat(gene name synonym)|uniprotkb:lat-RA(gene name synonym)|uniprotkb:DmORC3(gene name synonym)|uniprotkb:DmOrc3(gene name synonym)|uniprotkb:Dmel\CG4088(gene name synonym)|uniprotkb:LAT(gene name synonym)|uniprotkb:Lat(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC3(gene name synonym)|uniprotkb:"l(2)49Fd"(gene name synonym)|uniprotkb:"l(2)vr6"(gene name synonym)|uniprotkb:latheo(gene name synonym)|uniprotkb:orc3(gene name synonym)|uniprotkb:vr-6(gene name synonym)|uniprotkb:vr6(gene name synonym)|uniprotkb:CG4088(orf name)|uniprotkb:Dmel_CG4088(orf name) psi-mi:"MI:0030"(cross-linking study) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16148983|imex:IM-24404-5|dip:DIP-199046E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476904.1|flybase:FBgn0005654|refseq:NP_725260.1|dip:DIP-61503N|ensemblmetazoa:FBgn0005654(gene)|ensemblmetazoa:FBtr0087768(transcript)|ensemblmetazoa:FBtr0087769(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0008355"(olfactory learning)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR020795|interpro:IPR040855|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 refseq:NP_476904.1|flybase:FBgn0005654|refseq:NP_725260.1|dip:DIP-61503N|ensemblmetazoa:FBgn0005654(gene)|ensemblmetazoa:FBtr0087768(transcript)|ensemblmetazoa:FBtr0087769(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0008355"(olfactory learning)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR020795|interpro:IPR040855|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:vnTqJ3kfCs01ajCEbIp8u6K8NkQ7227 rogid:vnTqJ3kfCs01ajCEbIp8u6K8NkQ7227 rigid:z+qADZ1fVV/qUefi2XRemEm/74Q false sufficient binding region:47-721 sufficient binding region:47-721 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q24168 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-179453|intact:EBI-1631787|uniprotkb:Q9VFP4|ensemblmetazoa:FBpp0082329 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:orc2_drome(display_long)|uniprotkb:Orc2(gene name)|psi-mi:Orc2(display_short)|uniprotkb:CG3041(orf name) psi-mi:"MI:0410"(3D electron microscopy) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16148954|imex:IM-24404-4|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_731873.1|flybase:FBgn0015270|dip:DIP-23209N|ensemblmetazoa:FBgn0015270(gene)|ensemblmetazoa:FBtr0082866(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005723"(alpha-heterochromatin)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0030261"(chromosome condensation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:SaBA2xfoQcWtCiLhN6rD5O5yMhg7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924 sufficient binding region:266-618 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q24169 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-137663|uniprotkb:Q9V398|ensemblmetazoa:FBpp0080120 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:orc5_drome(display_long)|uniprotkb:Orc5(gene name)|psi-mi:Orc5(display_short)|uniprotkb:CG7833(orf name) psi-mi:"MI:0410"(3D electron microscopy) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16148954|imex:IM-24404-4|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_477132.1|flybase:FBgn0015271|dip:DIP-49320N|ensemblmetazoa:FBgn0015271(gene)|ensemblmetazoa:FBtr0080543(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:z+aa5qCMIPJJqDorJu/xRjCValE7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q9Y1B2 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-113296|uniprotkb:Q9V5C5|ensemblmetazoa:FBpp0087566 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:orc6_drome(display_long)|uniprotkb:Orc6(gene name)|psi-mi:Orc6(display_short)|uniprotkb:CG1584(orf name) psi-mi:"MI:0410"(3D electron microscopy) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16148954|imex:IM-24404-4|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_477319.1|flybase:FBgn0023180|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|ensemblmetazoa:FBgn0023180(gene)|ensemblmetazoa:FBtr0088482(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000808"(origin recognition complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR020529|rcsb pdb:4XGC|rcsb pdb:7JGR|dip:DIP-49258N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:1l2xkmHWJBVXCc+nGLx6RpjMec07227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924 sufficient binding region:187-257 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q7K2L1 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-182021|ensemblmetazoa:FBpp0086881|ensemblmetazoa:FBpp0086882 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:q7k2l1_drome(display_long)|uniprotkb:Orc3(gene name)|psi-mi:Orc3(display_short)|uniprotkb:CG34315-RB(gene name synonym)|uniprotkb:lat(gene name synonym)|uniprotkb:lat-RA(gene name synonym)|uniprotkb:DmORC3(gene name synonym)|uniprotkb:DmOrc3(gene name synonym)|uniprotkb:Dmel\CG4088(gene name synonym)|uniprotkb:LAT(gene name synonym)|uniprotkb:Lat(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC3(gene name synonym)|uniprotkb:"l(2)49Fd"(gene name synonym)|uniprotkb:"l(2)vr6"(gene name synonym)|uniprotkb:latheo(gene name synonym)|uniprotkb:orc3(gene name synonym)|uniprotkb:vr-6(gene name synonym)|uniprotkb:vr6(gene name synonym)|uniprotkb:CG4088(orf name)|uniprotkb:Dmel_CG4088(orf name) psi-mi:"MI:0410"(3D electron microscopy) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16148954|imex:IM-24404-4|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_476904.1|flybase:FBgn0005654|refseq:NP_725260.1|dip:DIP-61503N|ensemblmetazoa:FBgn0005654(gene)|ensemblmetazoa:FBtr0087768(transcript)|ensemblmetazoa:FBtr0087769(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0008355"(olfactory learning)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR020795|interpro:IPR040855|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:vnTqJ3kfCs01ajCEbIp8u6K8NkQ7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924 sufficient binding region:47-721 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16810 uniprotkb:Q9W102 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 intact:EBI-156676|ensemblmetazoa:FBpp0072330 psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:"MI:0410"(3D electron microscopy) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16148954|imex:IM-24404-4|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false sufficient binding region:533-924 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9W102 uniprotkb:Q9Y1B2 intact:EBI-156676|ensemblmetazoa:FBpp0072330 intact:EBI-113296|uniprotkb:Q9V5C5|ensemblmetazoa:FBpp0087566 psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:orc6_drome(display_long)|uniprotkb:Orc6(gene name)|psi-mi:Orc6(display_short)|uniprotkb:CG1584(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149142|imex:IM-24404-11|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 refseq:NP_477319.1|flybase:FBgn0023180|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|ensemblmetazoa:FBgn0023180(gene)|ensemblmetazoa:FBtr0088482(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000808"(origin recognition complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR020529|rcsb pdb:4XGC|rcsb pdb:7JGR|dip:DIP-49258N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rogid:1l2xkmHWJBVXCc+nGLx6RpjMec07227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false maltose binding protein tag:n-n sufficient binding region:187-257 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9W102 uniprotkb:Q24169 intact:EBI-156676|ensemblmetazoa:FBpp0072330 intact:EBI-137663|uniprotkb:Q9V398|ensemblmetazoa:FBpp0080120 psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:orc5_drome(display_long)|uniprotkb:Orc5(gene name)|psi-mi:Orc5(display_short)|uniprotkb:CG7833(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149142|imex:IM-24404-11|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 refseq:NP_477132.1|flybase:FBgn0015271|dip:DIP-49320N|ensemblmetazoa:FBgn0015271(gene)|ensemblmetazoa:FBtr0080543(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rogid:z+aa5qCMIPJJqDorJu/xRjCValE7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false maltose binding protein tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9W102 uniprotkb:Q7K2L1 intact:EBI-156676|ensemblmetazoa:FBpp0072330 intact:EBI-182021|ensemblmetazoa:FBpp0086881|ensemblmetazoa:FBpp0086882 psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:q7k2l1_drome(display_long)|uniprotkb:Orc3(gene name)|psi-mi:Orc3(display_short)|uniprotkb:CG34315-RB(gene name synonym)|uniprotkb:lat(gene name synonym)|uniprotkb:lat-RA(gene name synonym)|uniprotkb:DmORC3(gene name synonym)|uniprotkb:DmOrc3(gene name synonym)|uniprotkb:Dmel\CG4088(gene name synonym)|uniprotkb:LAT(gene name synonym)|uniprotkb:Lat(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC3(gene name synonym)|uniprotkb:"l(2)49Fd"(gene name synonym)|uniprotkb:"l(2)vr6"(gene name synonym)|uniprotkb:latheo(gene name synonym)|uniprotkb:orc3(gene name synonym)|uniprotkb:vr-6(gene name synonym)|uniprotkb:vr6(gene name synonym)|uniprotkb:CG4088(orf name)|uniprotkb:Dmel_CG4088(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149142|imex:IM-24404-11|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 refseq:NP_476904.1|flybase:FBgn0005654|refseq:NP_725260.1|dip:DIP-61503N|ensemblmetazoa:FBgn0005654(gene)|ensemblmetazoa:FBtr0087768(transcript)|ensemblmetazoa:FBtr0087769(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0008355"(olfactory learning)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR020795|interpro:IPR040855|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rogid:vnTqJ3kfCs01ajCEbIp8u6K8NkQ7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false maltose binding protein tag:n-n sufficient binding region:47-721 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9W102 uniprotkb:Q24168 intact:EBI-156676|ensemblmetazoa:FBpp0072330 intact:EBI-179453|intact:EBI-1631787|uniprotkb:Q9VFP4|ensemblmetazoa:FBpp0082329 psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:orc2_drome(display_long)|uniprotkb:Orc2(gene name)|psi-mi:Orc2(display_short)|uniprotkb:CG3041(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149142|imex:IM-24404-11|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 refseq:NP_731873.1|flybase:FBgn0015270|dip:DIP-23209N|ensemblmetazoa:FBgn0015270(gene)|ensemblmetazoa:FBtr0082866(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005723"(alpha-heterochromatin)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0030261"(chromosome condensation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rogid:SaBA2xfoQcWtCiLhN6rD5O5yMhg7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false maltose binding protein tag:n-n sufficient binding region:266-618 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9W102 uniprotkb:O16810 intact:EBI-156676|ensemblmetazoa:FBpp0072330 intact:EBI-90907|uniprotkb:Q9V4N1|ensemblmetazoa:FBpp0088033 psi-mi:q9w102_drome(display_long)|uniprotkb:Orc4(gene name)|psi-mi:Orc4(display_short)|uniprotkb:DmORC4(gene name synonym)|uniprotkb:Dmel\CG2917(gene name synonym)|uniprotkb:ORC(gene name synonym)|uniprotkb:ORC4(gene name synonym)|uniprotkb:dmOrc4(gene name synonym)|uniprotkb:orc4(gene name synonym)|uniprotkb:rDmORC(gene name synonym)|uniprotkb:CG2917(orf name)|uniprotkb:Dmel_CG2917(orf name) psi-mi:orc1_drome(display_long)|uniprotkb:Orc1(gene name)|psi-mi:Orc1(display_short)|uniprotkb:CG10667(orf name) psi-mi:"MI:0096"(pull down) Bleichert et al. (2015) pubmed:25762138|doi:10.1038/nature14239|imex:IM-24404 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16149142|imex:IM-24404-11|dip:DIP-199043E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477320.1|flybase:FBgn0023181|dip:DIP-49218N|ensemblmetazoa:FBgn0023181(gene)|ensemblmetazoa:FBtr0072425(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JGS|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962 refseq:NP_477303.1|ensemblmetazoa:FBtr0088959(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|ensemblmetazoa:FBgn0286788(gene)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:4XGC|rcsb pdb:7JGR|rcsb pdb:7JK2|rcsb pdb:7JK3|rcsb pdb:7JK4|rcsb pdb:7JK5|rcsb pdb:7JK6|reactome:R-DME-176187|reactome:R-DME-68616|reactome:R-DME-68689|reactome:R-DME-68827|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|rcsb pdb:7JGS|flybase:FBgn0286788|dip:DIP-59662N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)") - 2017/08/08 2017/08/10 rogid:7usr1tzBvg0PYEzm8eV1csNYW/07227 rogid:7pWy0a1ZJ4cfDIPw9aPU0AZh3MQ7227 rigid:QDJAU6rqpHhiS9CKQjt2warghCg false maltose binding protein tag:n-n sufficient binding region:533-924|his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)