#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8BLU0	uniprotkb:Q80TS3	intact:EBI-16146541|ensembl:ENSMUSP00000062171|ensembl:ENSMUSP00000105744|uniprotkb:Q6A073	intact:EBI-770665|uniprotkb:Q3UHI7|uniprotkb:Q3UM79|uniprotkb:Q504Z9|uniprotkb:Q5HZJ6|uniprotkb:Q80T56	psi-mi:flrt2_mouse(display_long)|uniprotkb:Flrt2(gene name)|psi-mi:Flrt2(display_short)|uniprotkb:Kiaa0405(gene name synonym)|uniprotkb:Fibronectin leucine rich transmembrane protein 2(gene name synonym)	psi-mi:agrl3_mouse(display_long)|uniprotkb:Adgrl3(gene name)|psi-mi:Adgrl3(display_short)|uniprotkb:Kiaa0768(gene name synonym)|uniprotkb:Latrophilin-3(gene name synonym)|uniprotkb:Lec3(gene name synonym)|uniprotkb:Lectomedin-3(gene name synonym)|uniprotkb:Lphn3(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Jackson et al. (2015)	pubmed:25728924|doi:"https://doi.org/10.1016/j.str.2015.01.013"|imex:IM-24218	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16146594|imex:IM-24218-1|dip:DIP-198744E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000047414(gene)|ensembl:ENSMUST00000057324(transcript)|ensembl:ENSMUST00000110117(transcript)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061343"(cell adhesion involved in heart morphogenesis)|go:"GO:0071711"(basement membrane organization)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032675|interpro:IPR036116|mint:Q8BLU0|rcsb pdb:4V2C|rcsb pdb:4V2D|rcsb pdb:5FTT|rcsb pdb:5FTU|reactome:R-MMU-5654687|interpro:IPR001611(Leucine-rich repeat)|dip:DIP-61401N|refseq:NP_958926.1|refseq:XP_006516118.1|refseq:XP_011242434.1	refseq:NP_941991.1|refseq:XP_011247767.1|refseq:XP_011247768.1|refseq:XP_011247773.1|refseq:NP_001334298.1|refseq:XP_017176402.1|dip:DIP-32218N|go:"GO:0001764"(neuron migration)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0031987"(locomotion involved in locomotory behavior)|go:"GO:0042220"(response to cocaine)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000203(GPS)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR000922(D-galactoside/L-rhamnose binding SUEL lectin)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR003334(GPCR, family 2, latrophilin, C-terminal)|interpro:IPR003924(GPCR, family 2, latrophilin)|interpro:IPR015630(GPCR, family 2, latrophilin, type 3)|interpro:IPR017981|interpro:IPR017983|interpro:IPR032471|interpro:IPR036445|interpro:IPR043159|rcsb pdb:4RMK|rcsb pdb:4RML|rcsb pdb:4YEB|rcsb pdb:5AFB|rcsb pdb:5FTT|rcsb pdb:5FTU|rcsb pdb:6JBU	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:gM+zL5eyX55UnQl/Tw/YauTG0FM10090	rogid:CzKvwTjsU4Ho2zkQ+aG9PGBgMRE10090	rigid:fOiZSOl0i5AuGpT4iz3dkQZwWZk	false	sufficient binding region:35-540	sufficient binding region:202-463|mutation disrupting interaction strength:294-294,292-292|mutation disrupting interaction strength:324-324,326-326|mutation decreasing interaction strength:246-246,244-244|mutation decreasing interaction strength:269-269,267-267	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8BLU0	uniprotkb:Q80TS3	intact:EBI-16146541|ensembl:ENSMUSP00000062171|ensembl:ENSMUSP00000105744|uniprotkb:Q6A073	intact:EBI-770665|uniprotkb:Q3UHI7|uniprotkb:Q3UM79|uniprotkb:Q504Z9|uniprotkb:Q5HZJ6|uniprotkb:Q80T56	psi-mi:flrt2_mouse(display_long)|uniprotkb:Flrt2(gene name)|psi-mi:Flrt2(display_short)|uniprotkb:Kiaa0405(gene name synonym)|uniprotkb:Fibronectin leucine rich transmembrane protein 2(gene name synonym)	psi-mi:agrl3_mouse(display_long)|uniprotkb:Adgrl3(gene name)|psi-mi:Adgrl3(display_short)|uniprotkb:Kiaa0768(gene name synonym)|uniprotkb:Latrophilin-3(gene name synonym)|uniprotkb:Lec3(gene name synonym)|uniprotkb:Lectomedin-3(gene name synonym)|uniprotkb:Lphn3(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Jackson et al. (2015)	pubmed:25728924|doi:"https://doi.org/10.1016/j.str.2015.01.013"|imex:IM-24218	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16146631|imex:IM-24218-2|dip:DIP-198744E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000047414(gene)|ensembl:ENSMUST00000057324(transcript)|ensembl:ENSMUST00000110117(transcript)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061343"(cell adhesion involved in heart morphogenesis)|go:"GO:0071711"(basement membrane organization)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032675|interpro:IPR036116|mint:Q8BLU0|rcsb pdb:4V2C|rcsb pdb:4V2D|rcsb pdb:5FTT|rcsb pdb:5FTU|reactome:R-MMU-5654687|interpro:IPR001611(Leucine-rich repeat)|dip:DIP-61401N|refseq:NP_958926.1|refseq:XP_006516118.1|refseq:XP_011242434.1	refseq:NP_941991.1|refseq:XP_011247767.1|refseq:XP_011247768.1|refseq:XP_011247773.1|refseq:NP_001334298.1|refseq:XP_017176402.1|dip:DIP-32218N|go:"GO:0001764"(neuron migration)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0031987"(locomotion involved in locomotory behavior)|go:"GO:0042220"(response to cocaine)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000203(GPS)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR000922(D-galactoside/L-rhamnose binding SUEL lectin)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR003334(GPCR, family 2, latrophilin, C-terminal)|interpro:IPR003924(GPCR, family 2, latrophilin)|interpro:IPR015630(GPCR, family 2, latrophilin, type 3)|interpro:IPR017981|interpro:IPR017983|interpro:IPR032471|interpro:IPR036445|interpro:IPR043159|rcsb pdb:4RMK|rcsb pdb:4RML|rcsb pdb:4YEB|rcsb pdb:5AFB|rcsb pdb:5FTT|rcsb pdb:5FTU|rcsb pdb:6JBU	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:gM+zL5eyX55UnQl/Tw/YauTG0FM10090	rogid:CzKvwTjsU4Ho2zkQ+aG9PGBgMRE10090	rigid:fOiZSOl0i5AuGpT4iz3dkQZwWZk	false	sufficient binding region:35-540|mutation disrupting interaction strength:188-188,186-186	sufficient binding region:202-463	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)