#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:E2RJV1 uniprotkb:P35240-1 intact:EBI-16145865|ensembl:ENSCAFP00000026921 intact:EBI-1014500|ensembl:ENSP00000344666 psi-mi:e2rjv1_canlf(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short) psi-mi:p35240-1(display_long)|uniprotkb:I(isoform synonym)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short)|uniprotkb:SCH(gene name synonym)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomerlin(gene name synonym)|uniprotkb:Schwannomin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Das et al. (2015) pubmed:25706233|doi:10.1038/ncb3115|imex:IM-24614 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16145904|imex:IM-24614-1|dip:DIP-199331E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000018218(gene)|ensembl:ENSCAFT00000028944(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|reactome:R-CFA-2028269|refseq:XP_005641760.1|refseq:XP_538144.2|dip:DIP-61621N intact:EBI-1014472(merl_human)|ensembl:ENSG00000186575(gene)|ensembl:ENST00000338641(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") - 2017/08/08 2017/08/10 rogid:oWvnnXrxe77cHKfT0ROb8VnSJ8k9615 rogid:YyzGKX6SmAvbiIgejNTvu/64uXc9606 rigid:n4sbbdWsNcA2qHDJLKbKAYt9ESI false - necessary binding region:488-595|ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:F1PFK4 uniprotkb:P35240-1 intact:EBI-16145946|ensembl:ENSCAFP00000005582 intact:EBI-1014500|ensembl:ENSP00000344666 psi-mi:f1pfk4_canlf(display_long)|uniprotkb:PARD3(gene name)|psi-mi:PARD3(display_short) psi-mi:p35240-1(display_long)|uniprotkb:I(isoform synonym)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short)|uniprotkb:SCH(gene name synonym)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomerlin(gene name synonym)|uniprotkb:Schwannomin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Das et al. (2015) pubmed:25706233|doi:10.1038/ncb3115|imex:IM-24614 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16145960|imex:IM-24614-3|dip:DIP-199333E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000003737(gene)|ensembl:ENSCAFT00000006022(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0008104"(protein localization)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031252"(cell leading edge)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051301"(cell division)|go:"GO:0051660"(establishment of centrosome localization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|reactome:R-CFA-2173791|reactome:R-CFA-420029|dip:DIP-61622N intact:EBI-1014472(merl_human)|ensembl:ENSG00000186575(gene)|ensembl:ENST00000338641(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") - 2017/08/08 2020/01/08 rogid:uVMpoMIug0iW/D8koPm8BxS6RHg9615 rogid:YyzGKX6SmAvbiIgejNTvu/64uXc9606 rigid:lrNbjBdr/lrWaXbDO7I64A3X6vo false - ha tag:?-?|sufficient binding region:1-325 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P35240-1 uniprotkb:F1PFK4 intact:EBI-1014500|ensembl:ENSP00000344666 intact:EBI-16145946|ensembl:ENSCAFP00000005582 psi-mi:p35240-1(display_long)|uniprotkb:I(isoform synonym)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short)|uniprotkb:SCH(gene name synonym)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomerlin(gene name synonym)|uniprotkb:Schwannomin(gene name synonym) psi-mi:f1pfk4_canlf(display_long)|uniprotkb:PARD3(gene name)|psi-mi:PARD3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Das et al. (2015) pubmed:25706233|doi:10.1038/ncb3115|imex:IM-24614 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16145983|imex:IM-24614-4|dip:DIP-199332E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1014472(merl_human)|ensembl:ENSG00000186575(gene)|ensembl:ENST00000338641(transcript) ensembl:ENSCAFG00000003737(gene)|ensembl:ENSCAFT00000006022(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0008104"(protein localization)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031252"(cell leading edge)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051301"(cell division)|go:"GO:0051660"(establishment of centrosome localization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|reactome:R-CFA-2173791|reactome:R-CFA-420029|dip:DIP-61622N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") - 2017/08/08 2020/01/08 rogid:YyzGKX6SmAvbiIgejNTvu/64uXc9606 rogid:uVMpoMIug0iW/D8koPm8BxS6RHg9615 rigid:C92J8ivZkTYerA9mdEK2qKy/vvc false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P35240-1 uniprotkb:E2RJV1 intact:EBI-1014500|ensembl:ENSP00000344666 intact:EBI-16145865|ensembl:ENSCAFP00000026921 psi-mi:p35240-1(display_long)|uniprotkb:I(isoform synonym)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short)|uniprotkb:SCH(gene name synonym)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomerlin(gene name synonym)|uniprotkb:Schwannomin(gene name synonym) psi-mi:e2rjv1_canlf(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Das et al. (2015) pubmed:25706233|doi:10.1038/ncb3115|imex:IM-24614 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16145983|imex:IM-24614-4|dip:DIP-199332E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1014472(merl_human)|ensembl:ENSG00000186575(gene)|ensembl:ENST00000338641(transcript) ensembl:ENSCAFG00000018218(gene)|ensembl:ENSCAFT00000028944(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|reactome:R-CFA-2028269|refseq:XP_005641760.1|refseq:XP_538144.2|dip:DIP-61621N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") - 2017/08/08 2020/01/08 rogid:YyzGKX6SmAvbiIgejNTvu/64uXc9606 rogid:oWvnnXrxe77cHKfT0ROb8VnSJ8k9615 rigid:C92J8ivZkTYerA9mdEK2qKy/vvc false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:E2QZZ2 uniprotkb:E2RJV1 intact:EBI-3891962|ensembl:ENSCAFP00000031455 intact:EBI-16145865|ensembl:ENSCAFP00000026921 psi-mi:e2qzz2_canlf(display_long)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short) psi-mi:e2rjv1_canlf(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Das et al. (2015) pubmed:25706233|doi:10.1038/ncb3115|imex:IM-24614 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16145927|imex:IM-24614-2|dip:DIP-199335E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61623N|ensembl:ENSCAFG00000012307(gene)|ensembl:ENSCAFT00000036114(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030175"(filopodium)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|reactome:R-CFA-2029482|reactome:R-CFA-5627123|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045177"(apical part of cell) ensembl:ENSCAFG00000018218(gene)|ensembl:ENSCAFT00000028944(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|reactome:R-CFA-2028269|refseq:XP_005641760.1|refseq:XP_538144.2|dip:DIP-61621N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") - 2017/08/08 2020/01/07 rogid:BBd0D6YZGrUcB7pzrGYQZc9Z26E9615 rogid:oWvnnXrxe77cHKfT0ROb8VnSJ8k9615 rigid:lSDQsI802ieBPa/naLBHsgdezEA false - ha tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:E2RJV1 uniprotkb:E2REM4 intact:EBI-16145865|ensembl:ENSCAFP00000026921 intact:EBI-16146005|ensembl:ENSCAFP00000025772 psi-mi:e2rjv1_canlf(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short) psi-mi:e2rem4_canlf(display_long)|uniprotkb:ARHGAP17(gene name)|psi-mi:ARHGAP17(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Das et al. (2015) pubmed:25706233|doi:10.1038/ncb3115|imex:IM-24614 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16146024|imex:IM-24614-5|dip:DIP-199334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000018218(gene)|ensembl:ENSCAFT00000028944(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|reactome:R-CFA-2028269|refseq:XP_005641760.1|refseq:XP_538144.2|dip:DIP-61621N ensembl:ENSCAFG00000017492(gene)|ensembl:ENSCAFT00000027716(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035020"(regulation of Rac protein signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR004148(BAR)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|reactome:R-CFA-9013148|reactome:R-CFA-9013149|reactome:R-CFA-9013404|reactome:R-CFA-9013405|dip:DIP-61624N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") - 2017/08/08 2020/01/07 rogid:oWvnnXrxe77cHKfT0ROb8VnSJ8k9615 rogid:PIgVKKJcII1ACefIk9UCXz5RCoc9615 rigid:OEc2S4WMRKhqEdQT6zYNk3M6Jgw false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:E2RJV1 uniprotkb:E2QZZ2 intact:EBI-16145865|ensembl:ENSCAFP00000026921 intact:EBI-3891962|ensembl:ENSCAFP00000031455 psi-mi:e2rjv1_canlf(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short) psi-mi:e2qzz2_canlf(display_long)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Das et al. (2015) pubmed:25706233|doi:10.1038/ncb3115|imex:IM-24614 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16146024|imex:IM-24614-5|dip:DIP-199334E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000018218(gene)|ensembl:ENSCAFT00000028944(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|reactome:R-CFA-2028269|refseq:XP_005641760.1|refseq:XP_538144.2|dip:DIP-61621N dip:DIP-61623N|ensembl:ENSCAFG00000012307(gene)|ensembl:ENSCAFT00000036114(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030175"(filopodium)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|reactome:R-CFA-2029482|reactome:R-CFA-5627123|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045177"(apical part of cell) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") - 2017/08/08 2020/01/07 rogid:oWvnnXrxe77cHKfT0ROb8VnSJ8k9615 rogid:BBd0D6YZGrUcB7pzrGYQZc9Z26E9615 rigid:OEc2S4WMRKhqEdQT6zYNk3M6Jgw false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)