#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O52821 uniprotkb:Q70AY8 intact:EBI-16144775 intact:EBI-16144757 psi-mi:o52821_amyor(display_long) psi-mi:q70ay8_actti(display_long)|uniprotkb:FHX34_108186(orf name)|uniprotkb:tcp20(gene name)|psi-mi:tcp20(display_short) psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis) Haslinger et al. (2015) pubmed:25686610|doi:"https://doi.org/10.1038/nature14141"|imex:IM-24575 taxid:31958(amyor)|taxid:31958(Amycolatopsis orientalis) taxid:1867(actti)|taxid:1867(actti) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16144795|imex:IM-24575-1|dip:DIP-199254E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003824"(catalytic activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0031177"(phosphopantetheine binding)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR001031(Thioesterase)|interpro:IPR001242(Condensation domain)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR020802|interpro:IPR020806|interpro:IPR020845|interpro:IPR023213|interpro:IPR025110|interpro:IPR029058|interpro:IPR036736|interpro:IPR010071(Amino acid adenylation)|dip:DIP-61591N go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0016705"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002397(Cytochrome P450, B-class)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4TVF|rcsb pdb:4TX3|rcsb pdb:6FSH|dip:DIP-61589N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:glY8jQgBsnvcSZJJzoPBoCutHR431958 rogid:+iyurKkWtUcEaIhxpEkMX6boJY01867 rigid:ad3p2ZTgOvgyqrPiiazCDVn6EEs false sufficient binding region:963-1860 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q70AZ6 uniprotkb:Q70AY8 intact:EBI-16144815 intact:EBI-16144757 psi-mi:q70az6_actti(display_long)|uniprotkb:tcp12(gene name)|psi-mi:tcp12(display_short) psi-mi:q70ay8_actti(display_long)|uniprotkb:FHX34_108186(orf name)|uniprotkb:tcp20(gene name)|psi-mi:tcp20(display_short) psi-mi:"MI:0114"(x-ray crystallography) Haslinger et al. (2015) pubmed:25686610|doi:"https://doi.org/10.1038/nature14141"|imex:IM-24575 taxid:1867(actti)|taxid:1867(actti) taxid:1867(actti)|taxid:1867(actti) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16144839|imex:IM-24575-2|dip:DIP-199251E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003824"(catalytic activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0031177"(phosphopantetheine binding)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR001031(Thioesterase)|interpro:IPR001242(Condensation domain)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR010071(Amino acid adenylation)|interpro:IPR020802|interpro:IPR020806|interpro:IPR020845|interpro:IPR023213|interpro:IPR025110|interpro:IPR029058|interpro:IPR036736|interpro:IPR042099|rcsb pdb:2MR7|rcsb pdb:2MR8|rcsb pdb:4TX2|dip:DIP-61590N go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0016705"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002397(Cytochrome P450, B-class)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4TVF|rcsb pdb:4TX3|rcsb pdb:6FSH|dip:DIP-61589N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:RgoNYa3RpujuVXcDzR81cPeoTfc1867 rogid:+iyurKkWtUcEaIhxpEkMX6boJY01867 rigid:f4Cs1uOxDMN0It1bKZgFiNYALAQ false sufficient binding region:1047-1511 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q70AZ6 uniprotkb:Q70AY8 intact:EBI-16144815 intact:EBI-16144757 psi-mi:q70az6_actti(display_long)|uniprotkb:tcp12(gene name)|psi-mi:tcp12(display_short) psi-mi:q70ay8_actti(display_long)|uniprotkb:FHX34_108186(orf name)|uniprotkb:tcp20(gene name)|psi-mi:tcp20(display_short) psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis) Haslinger et al. (2015) pubmed:25686610|doi:"https://doi.org/10.1038/nature14141"|imex:IM-24575 taxid:1867(actti)|taxid:1867(actti) taxid:1867(actti)|taxid:1867(actti) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16144858|imex:IM-24575-3|dip:DIP-199251E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003824"(catalytic activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0031177"(phosphopantetheine binding)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR001031(Thioesterase)|interpro:IPR001242(Condensation domain)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR010071(Amino acid adenylation)|interpro:IPR020802|interpro:IPR020806|interpro:IPR020845|interpro:IPR023213|interpro:IPR025110|interpro:IPR029058|interpro:IPR036736|interpro:IPR042099|rcsb pdb:2MR7|rcsb pdb:2MR8|rcsb pdb:4TX2|dip:DIP-61590N go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0016705"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002397(Cytochrome P450, B-class)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4TVF|rcsb pdb:4TX3|rcsb pdb:6FSH|dip:DIP-61589N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:RgoNYa3RpujuVXcDzR81cPeoTfc1867 rogid:+iyurKkWtUcEaIhxpEkMX6boJY01867 rigid:f4Cs1uOxDMN0It1bKZgFiNYALAQ false sufficient binding region:1047-1511 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8RN04 uniprotkb:O52821 intact:EBI-16144877 intact:EBI-16144775 psi-mi:c5b3_amyor(display_long)|uniprotkb:cyp165B3(gene name)|psi-mi:cyp165B3(display_short)|uniprotkb:oxyB(gene name synonym)|uniprotkb:Vancomycin biosynthesis protein OxyB(gene name synonym) psi-mi:o52821_amyor(display_long) psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis) Haslinger et al. (2015) pubmed:25686610|doi:"https://doi.org/10.1038/nature14141"|imex:IM-24575 taxid:31958(amyor)|taxid:31958(Amycolatopsis orientalis) taxid:31958(amyor)|taxid:31958(Amycolatopsis orientalis) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16144896|imex:IM-24575-4|dip:DIP-199256E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0016705"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0033072"(vancomycin biosynthetic process)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002397(Cytochrome P450, B-class)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:1LFK|rcsb pdb:1LG9|rcsb pdb:1LGF|dip:DIP-61594N go:"GO:0003824"(catalytic activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0031177"(phosphopantetheine binding)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR001031(Thioesterase)|interpro:IPR001242(Condensation domain)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR020802|interpro:IPR020806|interpro:IPR020845|interpro:IPR023213|interpro:IPR025110|interpro:IPR029058|interpro:IPR036736|interpro:IPR010071(Amino acid adenylation)|dip:DIP-61591N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:NsKrxaa8UTbLUTc2asAbFwrMD1g31958 rogid:glY8jQgBsnvcSZJJzoPBoCutHR431958 rigid:imCKMGQyHQ3qKNnGUc0ds95IR9Q false - sufficient binding region:1042-1506 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6ZZI8 uniprotkb:Q70AZ6 intact:EBI-11666705 intact:EBI-16144815 psi-mi:q6zzi8_actti(display_long)|uniprotkb:tcp18(gene name)|psi-mi:tcp18(display_short)|uniprotkb:FHX34_108188(orf name) psi-mi:q70az6_actti(display_long)|uniprotkb:tcp12(gene name)|psi-mi:tcp12(display_short) psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis) Haslinger et al. (2015) pubmed:25686610|doi:"https://doi.org/10.1038/nature14141"|imex:IM-24575 taxid:1867(actti)|taxid:1867(actti) taxid:1867(actti)|taxid:1867(actti) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16144915|imex:IM-24575-5|dip:DIP-199252E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0016705"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002397(Cytochrome P450, B-class)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:5HH3|dip:DIP-61592N go:"GO:0003824"(catalytic activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0031177"(phosphopantetheine binding)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR001031(Thioesterase)|interpro:IPR001242(Condensation domain)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR010071(Amino acid adenylation)|interpro:IPR020802|interpro:IPR020806|interpro:IPR020845|interpro:IPR023213|interpro:IPR025110|interpro:IPR029058|interpro:IPR036736|interpro:IPR042099|rcsb pdb:2MR7|rcsb pdb:2MR8|rcsb pdb:4TX2|dip:DIP-61590N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:BlUPD3ETLQRwwEuFp+n0VO2GyU41867 rogid:RgoNYa3RpujuVXcDzR81cPeoTfc1867 rigid:SX5CPPabSBXEIeI38/hvVODT7J8 false - sufficient binding region:1047-1511 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6ZZI8 uniprotkb:Q70AZ6 intact:EBI-11666705 intact:EBI-16144815 psi-mi:q6zzi8_actti(display_long)|uniprotkb:tcp18(gene name)|psi-mi:tcp18(display_short)|uniprotkb:FHX34_108188(orf name) psi-mi:q70az6_actti(display_long)|uniprotkb:tcp12(gene name)|psi-mi:tcp12(display_short) psi-mi:"MI:0071"(molecular sieving) Haslinger et al. (2015) pubmed:25686610|doi:"https://doi.org/10.1038/nature14141"|imex:IM-24575 taxid:1867(actti)|taxid:1867(actti) taxid:1867(actti)|taxid:1867(actti) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16144934|imex:IM-24575-6|dip:DIP-199252E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0016705"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002397(Cytochrome P450, B-class)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:5HH3|dip:DIP-61592N go:"GO:0003824"(catalytic activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0031177"(phosphopantetheine binding)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR001031(Thioesterase)|interpro:IPR001242(Condensation domain)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR010071(Amino acid adenylation)|interpro:IPR020802|interpro:IPR020806|interpro:IPR020845|interpro:IPR023213|interpro:IPR025110|interpro:IPR029058|interpro:IPR036736|interpro:IPR042099|rcsb pdb:2MR7|rcsb pdb:2MR8|rcsb pdb:4TX2|dip:DIP-61590N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:BlUPD3ETLQRwwEuFp+n0VO2GyU41867 rogid:RgoNYa3RpujuVXcDzR81cPeoTfc1867 rigid:SX5CPPabSBXEIeI38/hvVODT7J8 false - sufficient binding region:1047-1511 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q70AZ6 uniprotkb:Q70AY8 intact:EBI-16144815 intact:EBI-16144757 psi-mi:q70az6_actti(display_long)|uniprotkb:tcp12(gene name)|psi-mi:tcp12(display_short) psi-mi:q70ay8_actti(display_long)|uniprotkb:FHX34_108186(orf name)|uniprotkb:tcp20(gene name)|psi-mi:tcp20(display_short) psi-mi:"MI:0071"(molecular sieving) Haslinger et al. (2015) pubmed:25686610|doi:"https://doi.org/10.1038/nature14141"|imex:IM-24575 taxid:1867(actti)|taxid:1867(actti) taxid:1867(actti)|taxid:1867(actti) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16144953|imex:IM-24575-7|dip:DIP-199251E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003824"(catalytic activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0031177"(phosphopantetheine binding)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR001031(Thioesterase)|interpro:IPR001242(Condensation domain)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR010071(Amino acid adenylation)|interpro:IPR020802|interpro:IPR020806|interpro:IPR020845|interpro:IPR023213|interpro:IPR025110|interpro:IPR029058|interpro:IPR036736|interpro:IPR042099|rcsb pdb:2MR7|rcsb pdb:2MR8|rcsb pdb:4TX2|dip:DIP-61590N go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0016705"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0020037"(heme binding)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002397(Cytochrome P450, B-class)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:4TVF|rcsb pdb:4TX3|rcsb pdb:6FSH|dip:DIP-61589N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:RgoNYa3RpujuVXcDzR81cPeoTfc1867 rogid:+iyurKkWtUcEaIhxpEkMX6boJY01867 rigid:f4Cs1uOxDMN0It1bKZgFiNYALAQ false sufficient binding region:1047-1511|mutation disrupting interaction strength:1215-1215,1211-1211 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8RN04 uniprotkb:Q70AZ6 intact:EBI-16144877 intact:EBI-16144815 psi-mi:c5b3_amyor(display_long)|uniprotkb:cyp165B3(gene name)|psi-mi:cyp165B3(display_short)|uniprotkb:oxyB(gene name synonym)|uniprotkb:Vancomycin biosynthesis protein OxyB(gene name synonym) psi-mi:q70az6_actti(display_long)|uniprotkb:tcp12(gene name)|psi-mi:tcp12(display_short) psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis) Haslinger et al. (2015) pubmed:25686610|doi:"https://doi.org/10.1038/nature14141"|imex:IM-24575 taxid:31958(amyor)|taxid:31958(Amycolatopsis orientalis) taxid:1867(actti)|taxid:1867(actti) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16144976|imex:IM-24575-8|dip:DIP-199255E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0016705"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0033072"(vancomycin biosynthetic process)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002397(Cytochrome P450, B-class)|interpro:IPR017972|interpro:IPR036396|rcsb pdb:1LFK|rcsb pdb:1LG9|rcsb pdb:1LGF|dip:DIP-61594N go:"GO:0003824"(catalytic activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0031177"(phosphopantetheine binding)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR001031(Thioesterase)|interpro:IPR001242(Condensation domain)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR010071(Amino acid adenylation)|interpro:IPR020802|interpro:IPR020806|interpro:IPR020845|interpro:IPR023213|interpro:IPR025110|interpro:IPR029058|interpro:IPR036736|interpro:IPR042099|rcsb pdb:2MR7|rcsb pdb:2MR8|rcsb pdb:4TX2|dip:DIP-61590N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:NsKrxaa8UTbLUTc2asAbFwrMD1g31958 rogid:RgoNYa3RpujuVXcDzR81cPeoTfc1867 rigid:f3Y0Dzdrv5PSyzwMS3pcOXS+gAE false - sufficient binding region:968-1865 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q70AY6 uniprotkb:Q70AZ6 intact:EBI-16144995 intact:EBI-16144815 psi-mi:q70ay6_actti(display_long)|uniprotkb:tcp22(gene name)|psi-mi:tcp22(display_short) psi-mi:q70az6_actti(display_long)|uniprotkb:tcp12(gene name)|psi-mi:tcp12(display_short) psi-mi:"MI:0071"(molecular sieving) Haslinger et al. (2015) pubmed:25686610|doi:"https://doi.org/10.1038/nature14141"|imex:IM-24575 taxid:1867(actti)|taxid:1867(actti) taxid:1867(actti)|taxid:1867(actti) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16145008|imex:IM-24575-9|dip:DIP-199253E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0020037"(heme binding)|go:"GO:0016705"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002397(Cytochrome P450, B-class)|interpro:IPR017972|interpro:IPR036396|dip:DIP-61593N go:"GO:0003824"(catalytic activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0031177"(phosphopantetheine binding)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR001031(Thioesterase)|interpro:IPR001242(Condensation domain)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR010071(Amino acid adenylation)|interpro:IPR020802|interpro:IPR020806|interpro:IPR020845|interpro:IPR023213|interpro:IPR025110|interpro:IPR029058|interpro:IPR036736|interpro:IPR042099|rcsb pdb:2MR7|rcsb pdb:2MR8|rcsb pdb:4TX2|dip:DIP-61590N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:iiGqM1EWAT+1ZVpTremHYw7c2d01867 rogid:RgoNYa3RpujuVXcDzR81cPeoTfc1867 rigid:iHwLltCJba+AngFYyZFE5cssdPA false - sufficient binding region:1047-1511 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q70AY6 uniprotkb:Q70AZ6 intact:EBI-16144995 intact:EBI-16144815 psi-mi:q70ay6_actti(display_long)|uniprotkb:tcp22(gene name)|psi-mi:tcp22(display_short) psi-mi:q70az6_actti(display_long)|uniprotkb:tcp12(gene name)|psi-mi:tcp12(display_short) psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis) Haslinger et al. (2015) pubmed:25686610|doi:"https://doi.org/10.1038/nature14141"|imex:IM-24575 taxid:1867(actti)|taxid:1867(actti) taxid:1867(actti)|taxid:1867(actti) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16145027|imex:IM-24575-10|dip:DIP-199253E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0020037"(heme binding)|go:"GO:0016705"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002397(Cytochrome P450, B-class)|interpro:IPR017972|interpro:IPR036396|dip:DIP-61593N go:"GO:0003824"(catalytic activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0031177"(phosphopantetheine binding)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR001031(Thioesterase)|interpro:IPR001242(Condensation domain)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR010071(Amino acid adenylation)|interpro:IPR020802|interpro:IPR020806|interpro:IPR020845|interpro:IPR023213|interpro:IPR025110|interpro:IPR029058|interpro:IPR036736|interpro:IPR042099|rcsb pdb:2MR7|rcsb pdb:2MR8|rcsb pdb:4TX2|dip:DIP-61590N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:iiGqM1EWAT+1ZVpTremHYw7c2d01867 rogid:RgoNYa3RpujuVXcDzR81cPeoTfc1867 rigid:iHwLltCJba+AngFYyZFE5cssdPA false - sufficient binding region:1047-1511 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)