#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9CPX6	uniprotkb:Q8WUM4	intact:EBI-2911810|ensembl:ENSMUSP00000023343|uniprotkb:Q3TXJ9	intact:EBI-310624|uniprotkb:Q9BX86|uniprotkb:Q9NUN0|uniprotkb:Q9P2H2|uniprotkb:Q9UKL5|uniprotkb:C5MQH7|intact:EBI-10971645|uniprotkb:E9PFU1|uniprotkb:Q6NUS1|ensembl:ENSP00000307387|intact:EBI-28983290	psi-mi:atg3_mouse(display_long)|uniprotkb:Atg3(gene name)|psi-mi:Atg3(display_short)|uniprotkb:Apg3l(gene name synonym)|uniprotkb:Autophagy-related protein 3(gene name synonym)	psi-mi:pdc6i_human(display_long)|uniprotkb:PDCD6IP(gene name)|psi-mi:PDCD6IP(display_short)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1375(gene name synonym)|uniprotkb:ALIX(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:Hp95(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Murrow et al. (2015)	pubmed:25686249|doi:10.1038/ncb3112|imex:IM-24613	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16144559|imex:IM-24613-1|dip:DIP-199324E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000022663(gene)|ensembl:ENSMUST00000023343(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000153"(cytoplasmic ubiquitin ligase complex)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019776"(Atg8 ligase activity)|go:"GO:0019777"(Atg12 transferase activity)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR007135(Autophagocytosis associated protein, C-terminal)|mint:Q9CPX6|reactome:R-MMU-1632852|go:"GO:0016567"(protein ubiquitination)|refseq:NP_080678.1|dip:DIP-60109N	refseq:NP_037506.2|ensembl:ENSP00000307387|ensembl:ENST00000457054|ensembl:ENSP00000411825|refseq:NP_001155901.1|ensembl:ENSG00000170248(gene)|ensembl:ENST00000307296(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001772"(immunological synapse)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042470"(melanosome)|go:"GO:0042641"(actomyosin)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046755"(viral budding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090543"(Flemming body)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q8WUM4|rcsb pdb:2OEV|rcsb pdb:2OEW|rcsb pdb:2OEX|rcsb pdb:2OJQ|rcsb pdb:2R02|rcsb pdb:2R03|rcsb pdb:2R05|rcsb pdb:2XS1|rcsb pdb:2XS8|rcsb pdb:2ZNE|rcsb pdb:3C3O|rcsb pdb:3C3Q|rcsb pdb:3C3R|rcsb pdb:3E1R|rcsb pdb:3WUV|rcsb pdb:4JJY|rcsb pdb:5V3R|rcsb pdb:5WA1|rcsb pdb:6KP3|reactome:R-HSA-162588|reactome:R-HSA-5210891|reactome:R-HSA-5213460|reactome:R-HSA-5675482|refseq:NP_001243121.1|dip:DIP-29327N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:VW5Xh5I7A5K+xLjAfSmLLN4cftw10090	rogid:FYD19EyMBAGl204Xlgr4MlE8GMs9606	rigid:ZUkmCVnxmjj0GOyIQf5PZMdAD44	false	mutation disrupting interaction strength:243-243|ha tag:c-c	mcherry fluorescent protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9WU78-1	uniprotkb:Q9CQY1	intact:EBI-15788421|ensembl:ENSMUSP00000035086	intact:EBI-2911788|uniprotkb:Q3TKE5|uniprotkb:Q9D7Y5|ensembl:ENSMUSP00000038489	psi-mi:q9wu78-1(display_long)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym)	psi-mi:atg12_mouse(display_long)|uniprotkb:Atg12(gene name)|psi-mi:Atg12(display_short)|uniprotkb:Apg12(gene name synonym)|uniprotkb:Apg12l(gene name synonym)|uniprotkb:Autophagy-related protein 12(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Murrow et al. (2015)	pubmed:25686249|doi:10.1038/ncb3112|imex:IM-24613	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16144628|imex:IM-24613-3|dip:DIP-199326E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-641897(isoform-parent)|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript)	go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0044804"(autophagy of nucleus)|interpro:IPR007242(Autophagy protein 12)|interpro:IPR029071|mint:Q9CQY1|reactome:R-MMU-1632852|reactome:R-MMU-5205685|reactome:R-MMU-8934903|ensembl:ENSMUSG00000032905(gene)|ensembl:ENSMUST00000035648(transcript)|refseq:NP_080493.2|dip:DIP-57729N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/08	2017/08/10	rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090	rogid:VPDzzrLDhtPg3TwA3Qbhr5mB0CQ10090	rigid:v9qPBlDhe8oeeYcjc60b4vU4k3I	false	-	ha tag:n-n	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:Q9CQY1	uniprotkb:Q9CPX6	intact:EBI-2911788|uniprotkb:Q3TKE5|uniprotkb:Q9D7Y5|ensembl:ENSMUSP00000038489	intact:EBI-2911810|ensembl:ENSMUSP00000023343|uniprotkb:Q3TXJ9	psi-mi:atg12_mouse(display_long)|uniprotkb:Atg12(gene name)|psi-mi:Atg12(display_short)|uniprotkb:Apg12(gene name synonym)|uniprotkb:Apg12l(gene name synonym)|uniprotkb:Autophagy-related protein 12(gene name synonym)	psi-mi:atg3_mouse(display_long)|uniprotkb:Atg3(gene name)|psi-mi:Atg3(display_short)|uniprotkb:Apg3l(gene name synonym)|uniprotkb:Autophagy-related protein 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Murrow et al. (2015)	pubmed:25686249|doi:10.1038/ncb3112|imex:IM-24613	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16144647|imex:IM-24613-4|dip:DIP-199330E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0044804"(autophagy of nucleus)|interpro:IPR007242(Autophagy protein 12)|interpro:IPR029071|mint:Q9CQY1|reactome:R-MMU-1632852|reactome:R-MMU-5205685|reactome:R-MMU-8934903|ensembl:ENSMUSG00000032905(gene)|ensembl:ENSMUST00000035648(transcript)|refseq:NP_080493.2|dip:DIP-57729N	ensembl:ENSMUSG00000022663(gene)|ensembl:ENSMUST00000023343(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000153"(cytoplasmic ubiquitin ligase complex)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019776"(Atg8 ligase activity)|go:"GO:0019777"(Atg12 transferase activity)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR007135(Autophagocytosis associated protein, C-terminal)|mint:Q9CPX6|reactome:R-MMU-1632852|go:"GO:0016567"(protein ubiquitination)|refseq:NP_080678.1|dip:DIP-60109N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/08	2017/08/10	rogid:VPDzzrLDhtPg3TwA3Qbhr5mB0CQ10090	rogid:VW5Xh5I7A5K+xLjAfSmLLN4cftw10090	rigid:S2w9uhkTEDVTcvFCISSjsuldoE8	false	-	mutation disrupting interaction strength:243-243|v5 tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WU78-1	uniprotkb:Q9CQY1	intact:EBI-15788421|ensembl:ENSMUSP00000035086	intact:EBI-2911788|uniprotkb:Q3TKE5|uniprotkb:Q9D7Y5|ensembl:ENSMUSP00000038489	psi-mi:q9wu78-1(display_long)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym)	psi-mi:atg12_mouse(display_long)|uniprotkb:Atg12(gene name)|psi-mi:Atg12(display_short)|uniprotkb:Apg12(gene name synonym)|uniprotkb:Apg12l(gene name synonym)|uniprotkb:Autophagy-related protein 12(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Murrow et al. (2015)	pubmed:25686249|doi:10.1038/ncb3112|imex:IM-24613	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16144669|imex:IM-24613-5|dip:DIP-199326E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-641897(isoform-parent)|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript)	go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0044804"(autophagy of nucleus)|interpro:IPR007242(Autophagy protein 12)|interpro:IPR029071|mint:Q9CQY1|reactome:R-MMU-1632852|reactome:R-MMU-5205685|reactome:R-MMU-8934903|ensembl:ENSMUSG00000032905(gene)|ensembl:ENSMUST00000035648(transcript)|refseq:NP_080493.2|dip:DIP-57729N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/08	2017/08/10	rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090	rogid:VPDzzrLDhtPg3TwA3Qbhr5mB0CQ10090	rigid:v9qPBlDhe8oeeYcjc60b4vU4k3I	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CQY1	uniprotkb:Q9WU78-1	intact:EBI-2911788|uniprotkb:Q3TKE5|uniprotkb:Q9D7Y5|ensembl:ENSMUSP00000038489	intact:EBI-15788421|ensembl:ENSMUSP00000035086	psi-mi:atg12_mouse(display_long)|uniprotkb:Atg12(gene name)|psi-mi:Atg12(display_short)|uniprotkb:Apg12(gene name synonym)|uniprotkb:Apg12l(gene name synonym)|uniprotkb:Autophagy-related protein 12(gene name synonym)	psi-mi:q9wu78-1(display_long)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Murrow et al. (2015)	pubmed:25686249|doi:10.1038/ncb3112|imex:IM-24613	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16144686|imex:IM-24613-6|dip:DIP-199325E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0044804"(autophagy of nucleus)|interpro:IPR007242(Autophagy protein 12)|interpro:IPR029071|mint:Q9CQY1|reactome:R-MMU-1632852|reactome:R-MMU-5205685|reactome:R-MMU-8934903|ensembl:ENSMUSG00000032905(gene)|ensembl:ENSMUST00000035648(transcript)|refseq:NP_080493.2|dip:DIP-57729N	intact:EBI-641897(isoform-parent)|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/08	2017/08/10	rogid:VPDzzrLDhtPg3TwA3Qbhr5mB0CQ10090	rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090	rigid:uuSz3HdcpT2TdVzhLs1j4Hnmn8I	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CQY1	uniprotkb:Q9CPX6	intact:EBI-2911788|uniprotkb:Q3TKE5|uniprotkb:Q9D7Y5|ensembl:ENSMUSP00000038489	intact:EBI-2911810|ensembl:ENSMUSP00000023343|uniprotkb:Q3TXJ9	psi-mi:atg12_mouse(display_long)|uniprotkb:Atg12(gene name)|psi-mi:Atg12(display_short)|uniprotkb:Apg12(gene name synonym)|uniprotkb:Apg12l(gene name synonym)|uniprotkb:Autophagy-related protein 12(gene name synonym)	psi-mi:atg3_mouse(display_long)|uniprotkb:Atg3(gene name)|psi-mi:Atg3(display_short)|uniprotkb:Apg3l(gene name synonym)|uniprotkb:Autophagy-related protein 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Murrow et al. (2015)	pubmed:25686249|doi:10.1038/ncb3112|imex:IM-24613	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16144686|imex:IM-24613-6|dip:DIP-199325E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0044804"(autophagy of nucleus)|interpro:IPR007242(Autophagy protein 12)|interpro:IPR029071|mint:Q9CQY1|reactome:R-MMU-1632852|reactome:R-MMU-5205685|reactome:R-MMU-8934903|ensembl:ENSMUSG00000032905(gene)|ensembl:ENSMUST00000035648(transcript)|refseq:NP_080493.2|dip:DIP-57729N	ensembl:ENSMUSG00000022663(gene)|ensembl:ENSMUST00000023343(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000153"(cytoplasmic ubiquitin ligase complex)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019776"(Atg8 ligase activity)|go:"GO:0019777"(Atg12 transferase activity)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR007135(Autophagocytosis associated protein, C-terminal)|mint:Q9CPX6|reactome:R-MMU-1632852|go:"GO:0016567"(protein ubiquitination)|refseq:NP_080678.1|dip:DIP-60109N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/08	2017/08/10	rogid:VPDzzrLDhtPg3TwA3Qbhr5mB0CQ10090	rogid:VW5Xh5I7A5K+xLjAfSmLLN4cftw10090	rigid:uuSz3HdcpT2TdVzhLs1j4Hnmn8I	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9D8B3	uniprotkb:Q8WUM4	intact:EBI-8322817|uniprotkb:Q922P1|intact:MINT-4092439|uniprotkb:Q3TXM7|uniprotkb:Q91VM7|uniprotkb:A2AVM1|ensembl:ENSMUSP00000036206	intact:EBI-310624|uniprotkb:Q9BX86|uniprotkb:Q9NUN0|uniprotkb:Q9P2H2|uniprotkb:Q9UKL5|uniprotkb:C5MQH7|intact:EBI-10971645|uniprotkb:E9PFU1|uniprotkb:Q6NUS1|ensembl:ENSP00000307387|intact:EBI-28983290	psi-mi:chm4b_mouse(display_long)|uniprotkb:Chmp4b(gene name)|psi-mi:Chmp4b(display_short)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)	psi-mi:pdc6i_human(display_long)|uniprotkb:PDCD6IP(gene name)|psi-mi:PDCD6IP(display_short)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1375(gene name synonym)|uniprotkb:ALIX(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:Hp95(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Murrow et al. (2015)	pubmed:25686249|doi:10.1038/ncb3112|imex:IM-24613	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16144704|imex:IM-24613-7|dip:DIP-199328E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_083638.1|dip:DIP-61322N|ensembl:ENSMUSG00000038467(gene)|ensembl:ENSMUST00000044277(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9D8B3|reactome:R-MMU-1632852|reactome:R-MMU-5620971|reactome:R-MMU-917729|reactome:R-MMU-9668328	refseq:NP_037506.2|ensembl:ENSP00000307387|ensembl:ENST00000457054|ensembl:ENSP00000411825|refseq:NP_001155901.1|ensembl:ENSG00000170248(gene)|ensembl:ENST00000307296(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001772"(immunological synapse)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042470"(melanosome)|go:"GO:0042641"(actomyosin)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046755"(viral budding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090543"(Flemming body)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q8WUM4|rcsb pdb:2OEV|rcsb pdb:2OEW|rcsb pdb:2OEX|rcsb pdb:2OJQ|rcsb pdb:2R02|rcsb pdb:2R03|rcsb pdb:2R05|rcsb pdb:2XS1|rcsb pdb:2XS8|rcsb pdb:2ZNE|rcsb pdb:3C3O|rcsb pdb:3C3Q|rcsb pdb:3C3R|rcsb pdb:3E1R|rcsb pdb:3WUV|rcsb pdb:4JJY|rcsb pdb:5V3R|rcsb pdb:5WA1|rcsb pdb:6KP3|reactome:R-HSA-162588|reactome:R-HSA-5210891|reactome:R-HSA-5213460|reactome:R-HSA-5675482|refseq:NP_001243121.1|dip:DIP-29327N	psi-mi:"MI:0465"(dip)	comment:mint|function:"Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. In the ESCRT-III complex, it probably serves as an acceptor for ESCRT-I complex on endosomal membranes"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:7ObtifCzEVN9ohyQMVv/eHUJd+810090	rogid:FYD19EyMBAGl204Xlgr4MlE8GMs9606	rigid:MiTB4i3fSbzP/LuX2HaKg86OLVk	false	myc tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P26806	uniprotkb:Q8WUM4	intact:EBI-16144585	intact:EBI-310624|uniprotkb:Q9BX86|uniprotkb:Q9NUN0|uniprotkb:Q9P2H2|uniprotkb:Q9UKL5|uniprotkb:C5MQH7|intact:EBI-10971645|uniprotkb:E9PFU1|uniprotkb:Q6NUS1|ensembl:ENSP00000307387|intact:EBI-28983290	psi-mi:gag_mlvff(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Core polyprotein(gene name synonym)	psi-mi:pdc6i_human(display_long)|uniprotkb:PDCD6IP(gene name)|psi-mi:PDCD6IP(display_short)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1375(gene name synonym)|uniprotkb:ALIX(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:Hp95(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Murrow et al. (2015)	pubmed:25686249|doi:10.1038/ncb3112|imex:IM-24613	taxid:11797(mlvff)|taxid:11797("Friend murine leukemia virus (isolate FB29)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16144609|imex:IM-24613-2|dip:DIP-199329E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003723"(RNA binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0072494"(host multivesicular body)|interpro:IPR000840(Gamma-retroviral matrix, N-terminal)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002079(Gag polyprotein, inner coat protein p12)|interpro:IPR003036(Core shell protein Gag P30)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR036875|interpro:IPR036946|refseq:NP_040332.1|dip:DIP-61620N	refseq:NP_037506.2|ensembl:ENSP00000307387|ensembl:ENST00000457054|ensembl:ENSP00000411825|refseq:NP_001155901.1|ensembl:ENSG00000170248(gene)|ensembl:ENST00000307296(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001772"(immunological synapse)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042470"(melanosome)|go:"GO:0042641"(actomyosin)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046755"(viral budding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090543"(Flemming body)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q8WUM4|rcsb pdb:2OEV|rcsb pdb:2OEW|rcsb pdb:2OEX|rcsb pdb:2OJQ|rcsb pdb:2R02|rcsb pdb:2R03|rcsb pdb:2R05|rcsb pdb:2XS1|rcsb pdb:2XS8|rcsb pdb:2ZNE|rcsb pdb:3C3O|rcsb pdb:3C3Q|rcsb pdb:3C3R|rcsb pdb:3E1R|rcsb pdb:3WUV|rcsb pdb:4JJY|rcsb pdb:5V3R|rcsb pdb:5WA1|rcsb pdb:6KP3|reactome:R-HSA-162588|reactome:R-HSA-5210891|reactome:R-HSA-5213460|reactome:R-HSA-5675482|refseq:NP_001243121.1|dip:DIP-29327N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:cgX8kKCI/8eJQWcnnjMIm5/cOA011797	rogid:FYD19EyMBAGl204Xlgr4MlE8GMs9606	rigid:dXiyiqwag/SzvJGWhh2JDbvIslg	false	yellow fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9CQY1	uniprotkb:Q8WUM4	intact:EBI-2911788|uniprotkb:Q3TKE5|uniprotkb:Q9D7Y5|ensembl:ENSMUSP00000038489	intact:EBI-310624|uniprotkb:Q9BX86|uniprotkb:Q9NUN0|uniprotkb:Q9P2H2|uniprotkb:Q9UKL5|uniprotkb:C5MQH7|intact:EBI-10971645|uniprotkb:E9PFU1|uniprotkb:Q6NUS1|ensembl:ENSP00000307387|intact:EBI-28983290	psi-mi:atg12_mouse(display_long)|uniprotkb:Atg12(gene name)|psi-mi:Atg12(display_short)|uniprotkb:Apg12(gene name synonym)|uniprotkb:Apg12l(gene name synonym)|uniprotkb:Autophagy-related protein 12(gene name synonym)	psi-mi:pdc6i_human(display_long)|uniprotkb:PDCD6IP(gene name)|psi-mi:PDCD6IP(display_short)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1375(gene name synonym)|uniprotkb:ALIX(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:Hp95(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Murrow et al. (2015)	pubmed:25686249|doi:10.1038/ncb3112|imex:IM-24613	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16144723|imex:IM-24613-8|dip:DIP-199327E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0044804"(autophagy of nucleus)|interpro:IPR007242(Autophagy protein 12)|interpro:IPR029071|mint:Q9CQY1|reactome:R-MMU-1632852|reactome:R-MMU-5205685|reactome:R-MMU-8934903|ensembl:ENSMUSG00000032905(gene)|ensembl:ENSMUST00000035648(transcript)|refseq:NP_080493.2|dip:DIP-57729N	refseq:NP_037506.2|ensembl:ENSP00000307387|ensembl:ENST00000457054|ensembl:ENSP00000411825|refseq:NP_001155901.1|ensembl:ENSG00000170248(gene)|ensembl:ENST00000307296(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001772"(immunological synapse)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042470"(melanosome)|go:"GO:0042641"(actomyosin)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046755"(viral budding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090543"(Flemming body)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q8WUM4|rcsb pdb:2OEV|rcsb pdb:2OEW|rcsb pdb:2OEX|rcsb pdb:2OJQ|rcsb pdb:2R02|rcsb pdb:2R03|rcsb pdb:2R05|rcsb pdb:2XS1|rcsb pdb:2XS8|rcsb pdb:2ZNE|rcsb pdb:3C3O|rcsb pdb:3C3Q|rcsb pdb:3C3R|rcsb pdb:3E1R|rcsb pdb:3WUV|rcsb pdb:4JJY|rcsb pdb:5V3R|rcsb pdb:5WA1|rcsb pdb:6KP3|reactome:R-HSA-162588|reactome:R-HSA-5210891|reactome:R-HSA-5213460|reactome:R-HSA-5675482|refseq:NP_001243121.1|dip:DIP-29327N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:VPDzzrLDhtPg3TwA3Qbhr5mB0CQ10090	rogid:FYD19EyMBAGl204Xlgr4MlE8GMs9606	rigid:bpEgVwqb2FKvURfMykMbLTzbkZw	false	yellow fluorescent protein tag:n-n	mcherry fluorescent protein tag:n-n|sufficient binding region:1-359|sufficient binding region:360-702	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)