#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9ET38	uniprotkb:P01558	intact:EBI-8036280|intact:MINT-1771795|uniprotkb:Q8R4B7|ensembl:ENSMUSP00000081334	intact:EBI-16142958|uniprotkb:O32373|uniprotkb:O52925|uniprotkb:Q05130|uniprotkb:Q46182|uniprotkb:Q79AH6|uniprotkb:Q79DV9|uniprotkb:Q79DW4|uniprotkb:Q79DX2|uniprotkb:Q8GNM6|uniprotkb:Q9R457	psi-mi:cld19_mouse(display_long)|uniprotkb:Cldn19(gene name)|psi-mi:Cldn19(display_short)	psi-mi:eltb_clopf(display_long)|uniprotkb:cpe(gene name)|psi-mi:cpe(display_short)	psi-mi:"MI:0071"(molecular sieving)	Saitoh et al. (2015)	pubmed:25678664|doi:10.1126/science.1261833|imex:IM-24332	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:1502(clostridium perfring)|taxid:1502(Clostridium perfringens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16142989|imex:IM-24332-1|dip:DIP-198958E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001033679.1|refseq:NP_694745.1|dip:DIP-42881N|ensembl:ENSMUSG00000066058(gene)|ensembl:ENSMUST00000084309(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0120193"(tight junction organization)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1901890"(positive regulation of cell junction assembly)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR006187(Claudin)|interpro:IPR017974|rcsb pdb:3X29	go:"GO:0005576"(extracellular region)|go:"GO:0090729"(toxin activity)|interpro:IPR003897(Clostridium enterotoxin)|rcsb pdb:2QUO|rcsb pdb:2XH6|rcsb pdb:2YHJ|rcsb pdb:3AM2|rcsb pdb:3X29|rcsb pdb:3ZIW|rcsb pdb:3ZIX|rcsb pdb:4P5H|rcsb pdb:5B2G|rcsb pdb:6AKE|rcsb pdb:6AKF|rcsb pdb:6AKG|rcsb pdb:6OV2|rcsb pdb:6OV3|rcsb pdb:7KP4|refseq:WP_003470007.1|refseq:YP_473485.1|dip:DIP-61488N|refseq:YP_473394.1	psi-mi:"MI:0465"(dip)	comment:mint|function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:NC33RbgWuPs00nETT2b/D4Fk3LI10090	rogid:E3231ePSkbEZ9SBahfm2Ew/oo781502	rigid:Wxa13FuJLViTVAuHv49NRNkI/9Q	false	mutation decreasing interaction strength:150-150|mutation decreasing interaction strength:41-41|mutation decreasing interaction strength:40-40|mutation decreasing interaction strength:39-39|mutation decreasing interaction strength:35-35|mutation decreasing interaction strength:159-159|mutation decreasing interaction strength:154-154|mutation decreasing interaction strength:156-156|mutation decreasing interaction strength:152-152|mutation decreasing interaction strength:153-153|mutation decreasing interaction strength:151-151|mutation decreasing interaction strength:40-40|mutation decreasing interaction strength:41-41|mutation decreasing interaction strength:154-154|mutation decreasing interaction strength:150-150|mutation decreasing interaction strength:151-151|mutation decreasing interaction strength:39-39|mutation decreasing interaction strength:150-150|mutation decreasing interaction strength:150-150|mutation decreasing interaction strength:150-150|mutation decreasing interaction strength:150-150|mutation decreasing interaction strength:41-41|mutation decreasing interaction strength:40-40|mutation decreasing interaction strength:40-40|mutation decreasing interaction strength:159-159	sufficient binding region:194-319	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Z0G9	uniprotkb:P01558	intact:EBI-7158584|ensembl:ENSMUSP00000091799|uniprotkb:Q91X40|intact:MINT-113483	intact:EBI-16142958|uniprotkb:O32373|uniprotkb:O52925|uniprotkb:Q05130|uniprotkb:Q46182|uniprotkb:Q79AH6|uniprotkb:Q79DV9|uniprotkb:Q79DW4|uniprotkb:Q79DX2|uniprotkb:Q8GNM6|uniprotkb:Q9R457	psi-mi:cld3_mouse(display_long)|uniprotkb:Cldn3(gene name)|psi-mi:Cldn3(display_short)|uniprotkb:Cpetr2(gene name synonym)|uniprotkb:Clostridium perfringens enterotoxin receptor 2(gene name synonym)	psi-mi:eltb_clopf(display_long)|uniprotkb:cpe(gene name)|psi-mi:cpe(display_short)	psi-mi:"MI:0071"(molecular sieving)	Saitoh et al. (2015)	pubmed:25678664|doi:10.1126/science.1261833|imex:IM-24332	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:1502(clostridium perfring)|taxid:1502(Clostridium perfringens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16143069|imex:IM-24332-2|dip:DIP-198959E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000070473(gene)|ensembl:ENSMUST00000094245(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014045"(establishment of endothelial blood-brain barrier)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034331"(cell junction maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045471"(response to ethanol)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070160"(tight junction)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1901890"(positive regulation of cell junction assembly)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1905050"(positive regulation of metallopeptidase activity)|interpro:IPR003549(Claudin-3)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR006187(Claudin)|interpro:IPR017974|rcsb pdb:6AKE|rcsb pdb:6AKF|rcsb pdb:6AKG|refseq:NP_034032.1|dip:DIP-40779N	go:"GO:0005576"(extracellular region)|go:"GO:0090729"(toxin activity)|interpro:IPR003897(Clostridium enterotoxin)|rcsb pdb:2QUO|rcsb pdb:2XH6|rcsb pdb:2YHJ|rcsb pdb:3AM2|rcsb pdb:3X29|rcsb pdb:3ZIW|rcsb pdb:3ZIX|rcsb pdb:4P5H|rcsb pdb:5B2G|rcsb pdb:6AKE|rcsb pdb:6AKF|rcsb pdb:6AKG|rcsb pdb:6OV2|rcsb pdb:6OV3|rcsb pdb:7KP4|refseq:WP_003470007.1|refseq:YP_473485.1|dip:DIP-61488N|refseq:YP_473394.1	psi-mi:"MI:0465"(dip)	comment:mint|function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:1NbVPFbbqYLPehRqqbLFoCG8SQI10090	rogid:E3231ePSkbEZ9SBahfm2Ew/oo781502	rigid:0uRrfyvCxs8vds4/aEfV7F+vnsk	false	-	sufficient binding region:194-319	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9ET38	uniprotkb:P01558	intact:EBI-8036280|intact:MINT-1771795|uniprotkb:Q8R4B7|ensembl:ENSMUSP00000081334	intact:EBI-16142958|uniprotkb:O32373|uniprotkb:O52925|uniprotkb:Q05130|uniprotkb:Q46182|uniprotkb:Q79AH6|uniprotkb:Q79DV9|uniprotkb:Q79DW4|uniprotkb:Q79DX2|uniprotkb:Q8GNM6|uniprotkb:Q9R457	psi-mi:cld19_mouse(display_long)|uniprotkb:Cldn19(gene name)|psi-mi:Cldn19(display_short)	psi-mi:eltb_clopf(display_long)|uniprotkb:cpe(gene name)|psi-mi:cpe(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Saitoh et al. (2015)	pubmed:25678664|doi:10.1126/science.1261833|imex:IM-24332	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:1502(clostridium perfring)|taxid:1502(Clostridium perfringens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16143089|imex:IM-24332-3|dip:DIP-198958E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001033679.1|refseq:NP_694745.1|dip:DIP-42881N|ensembl:ENSMUSG00000066058(gene)|ensembl:ENSMUST00000084309(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0120193"(tight junction organization)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1901890"(positive regulation of cell junction assembly)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR006187(Claudin)|interpro:IPR017974|rcsb pdb:3X29	go:"GO:0005576"(extracellular region)|go:"GO:0090729"(toxin activity)|interpro:IPR003897(Clostridium enterotoxin)|rcsb pdb:2QUO|rcsb pdb:2XH6|rcsb pdb:2YHJ|rcsb pdb:3AM2|rcsb pdb:3X29|rcsb pdb:3ZIW|rcsb pdb:3ZIX|rcsb pdb:4P5H|rcsb pdb:5B2G|rcsb pdb:6AKE|rcsb pdb:6AKF|rcsb pdb:6AKG|rcsb pdb:6OV2|rcsb pdb:6OV3|rcsb pdb:7KP4|refseq:WP_003470007.1|refseq:YP_473485.1|dip:DIP-61488N|refseq:YP_473394.1	psi-mi:"MI:0465"(dip)	comment:mint|function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:NC33RbgWuPs00nETT2b/D4Fk3LI10090	rogid:E3231ePSkbEZ9SBahfm2Ew/oo781502	rigid:Wxa13FuJLViTVAuHv49NRNkI/9Q	false	-	sufficient binding region:203-319	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)