#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P83949 uniprotkb:P40427 intact:EBI-202590|uniprotkb:P02834|uniprotkb:Q9TX83|uniprotkb:Q9VER4|uniprotkb:Q9VER5|ensemblmetazoa:FBpp0082793 intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515 psi-mi:ubx_drome(display_long)|uniprotkb:Ubx(gene name)|psi-mi:Ubx(display_short)|uniprotkb:CG10388(orf name) psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name) psi-mi:"MI:0114"(x-ray crystallography) Foos et al. (2015) pubmed:25651060|doi:10.1016/j.str.2014.12.011|imex:IM-24205 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16141295|imex:IM-24205-1|dip:DIP-61785E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_536748.1|refseq:NP_536752.1|refseq:NP_732171.1|refseq:NP_732172.1|refseq:NP_732173.1|refseq:NP_996219.1|flybase:FBgn0003944|dip:DIP-33048N|ensemblmetazoa:FBgn0003944(gene)|ensemblmetazoa:FBtr0083347(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001706"(endoderm formation)|go:"GO:0001709"(cell fate determination)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007384"(specification of segmental identity, thorax)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007482"(haltere development)|go:"GO:0007494"(midgut development)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0007507"(heart development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010092"(specification of animal organ identity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035052"(dorsal vessel aortic cell fate commitment)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048636"(positive regulation of muscle organ development)|go:"GO:0060969"(obsolete negative regulation of gene silencing)|go:"GO:0061327"(anterior Malpighian tubule development)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1B8I|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:4UUT refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:PciTV5UxWTqbliI2WZAasPEr42g7227 rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227 rigid:M+fmYYjItm5I/cFREJYtr3DsNrM false sufficient binding region:233-367 sufficient binding region:238-312 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P83949 uniprotkb:P40427 intact:EBI-202590|uniprotkb:P02834|uniprotkb:Q9TX83|uniprotkb:Q9VER4|uniprotkb:Q9VER5|ensemblmetazoa:FBpp0082793 intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515 psi-mi:ubx_drome(display_long)|uniprotkb:Ubx(gene name)|psi-mi:Ubx(display_short)|uniprotkb:CG10388(orf name) psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name) psi-mi:"MI:0071"(molecular sieving) Foos et al. (2015) pubmed:25651060|doi:10.1016/j.str.2014.12.011|imex:IM-24205 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16141316|imex:IM-24205-2|dip:DIP-61785E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_536748.1|refseq:NP_536752.1|refseq:NP_732171.1|refseq:NP_732172.1|refseq:NP_732173.1|refseq:NP_996219.1|flybase:FBgn0003944|dip:DIP-33048N|ensemblmetazoa:FBgn0003944(gene)|ensemblmetazoa:FBtr0083347(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001706"(endoderm formation)|go:"GO:0001709"(cell fate determination)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007384"(specification of segmental identity, thorax)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007482"(haltere development)|go:"GO:0007494"(midgut development)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0007507"(heart development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010092"(specification of animal organ identity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035052"(dorsal vessel aortic cell fate commitment)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048636"(positive regulation of muscle organ development)|go:"GO:0060969"(obsolete negative regulation of gene silencing)|go:"GO:0061327"(anterior Malpighian tubule development)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1B8I|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:4UUT refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:PciTV5UxWTqbliI2WZAasPEr42g7227 rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227 rigid:M+fmYYjItm5I/cFREJYtr3DsNrM false sufficient binding region:292-367 sufficient binding region:238-312 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P83949 uniprotkb:P40427 intact:EBI-202590|uniprotkb:P02834|uniprotkb:Q9TX83|uniprotkb:Q9VER4|uniprotkb:Q9VER5|ensemblmetazoa:FBpp0082793 intact:EBI-101537|uniprotkb:A4V4K5|uniprotkb:Q0KHS1|uniprotkb:Q9V3S2|ensemblmetazoa:FBpp0073940|ensemblmetazoa:FBpp0073942|ensemblmetazoa:FBpp0305514|ensemblmetazoa:FBpp0305515 psi-mi:ubx_drome(display_long)|uniprotkb:Ubx(gene name)|psi-mi:Ubx(display_short)|uniprotkb:CG10388(orf name) psi-mi:exd_drome(display_long)|uniprotkb:exd(gene name)|psi-mi:exd(display_short)|uniprotkb:CG8933(orf name) psi-mi:"MI:0114"(x-ray crystallography) Foos et al. (2015) pubmed:25651060|doi:10.1016/j.str.2014.12.011|imex:IM-24205 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16141338|imex:IM-24205-3|dip:DIP-61785E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_536748.1|refseq:NP_536752.1|refseq:NP_732171.1|refseq:NP_732172.1|refseq:NP_732173.1|refseq:NP_996219.1|flybase:FBgn0003944|dip:DIP-33048N|ensemblmetazoa:FBgn0003944(gene)|ensemblmetazoa:FBtr0083347(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001706"(endoderm formation)|go:"GO:0001709"(cell fate determination)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007384"(specification of segmental identity, thorax)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007482"(haltere development)|go:"GO:0007494"(midgut development)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0007507"(heart development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010092"(specification of animal organ identity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035052"(dorsal vessel aortic cell fate commitment)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048636"(positive regulation of muscle organ development)|go:"GO:0060969"(obsolete negative regulation of gene silencing)|go:"GO:0061327"(anterior Malpighian tubule development)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1B8I|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:4UUT refseq:NP_523360.1|refseq:NP_727923.1|flybase:FBgn0000611|ensemblmetazoa:FBgn0000611(gene)|ensemblmetazoa:FBtr0074135(transcript)|ensemblmetazoa:FBtr0074137(transcript)|ensemblmetazoa:FBtr0333322(transcript)|ensemblmetazoa:FBtr0333323(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007432"(salivary gland boundary specification)|go:"GO:0007438"(oenocyte development)|go:"GO:0007525"(somatic muscle development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B8I|rcsb pdb:2R5Y|rcsb pdb:2R5Z|rcsb pdb:4CYC|rcsb pdb:4UUS|rcsb pdb:5ZJQ|rcsb pdb:5ZJR|rcsb pdb:5ZJS|rcsb pdb:5ZJT|refseq:NP_001259592.1|refseq:NP_001259593.1|dip:DIP-18773N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:PciTV5UxWTqbliI2WZAasPEr42g7227 rogid:BU1TH5bNahyZRxxL8K3gEzHJ4TE7227 rigid:M+fmYYjItm5I/cFREJYtr3DsNrM false sufficient binding region:292-367 sufficient binding region:238-312 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)