#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:15664"	uniprotkb:O00481	intact:EBI-14033571|chebi:"CHEBI:632"|chebi:"CHEBI:10952"	intact:EBI-2809309|ensembl:ENSP00000289361|uniprotkb:Q147X5|uniprotkb:A2A278|uniprotkb:Q53F15|uniprotkb:Q99420|uniprotkb:Q0P515|uniprotkb:Q9HCY1|uniprotkb:A8K2C8|uniprotkb:B4DIQ1|uniprotkb:E9PHG8|uniprotkb:B4DRM2|uniprotkb:E9PGB4	psi-mi:"(2e)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate"(display_short)|psi-mi:"CHEBI:15664"(display_long)|intact:"(2E)-4-hydroxy-3-methylbut-2-en-1-yl pyrophosphate"(synonym)|intact:"(E)-4-hydroxy-3-methyl-2-buten-1-yl diphosphate"(synonym)|intact:"(E)-4-hydroxy-3-methyl-2-buten-1-yl pyrophosphate"(synonym)|intact:"(E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate"(synonym)|intact:"(E)-4-Hydroxy-3-methylbut-2-en-1-yl diphosphate"(synonym)|intact:"(E)-4-Hydroxy-3-methylbut-2-enyl diphosphate"(synonym)|intact:"(E)-4-hydroxy-3-methylbut-2-enyl pyrophosphate"(synonym)|intact:1-Hydroxy-2-methyl-2-butenyl 4-diphosphate(synonym)|intact:"1-hydroxy-2-methylbut-2(E)-en-4-yl diphosphate"(synonym)|intact:"1-hydroxy-2-methylbut-2(E)-en-4-yl pyrophosphate"(synonym)|intact:HMBPP(synonym)|intact:"(2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate"(iupac name)	psi-mi:bt3a1_human(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Rhodes et al. (2015)	pubmed:25637025|imex:IM-25688	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14033563|imex:IM-25688-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000026950(gene)|ensembl:ENST00000289361(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037954|interpro:IPR043136|rcsb pdb:4F80|rcsb pdb:4F9L|rcsb pdb:4F9P|rcsb pdb:4JKW|rcsb pdb:4K55|rcsb pdb:4N7I|rcsb pdb:4N7U|rcsb pdb:4V1P|rcsb pdb:5HM7|rcsb pdb:5LYG|rcsb pdb:5LYK|rcsb pdb:5ZXK|rcsb pdb:6ISM|rcsb pdb:6ITA|rcsb pdb:6J06|rcsb pdb:6XLQ|reactome:R-HSA-8851680|refseq:NP_001138480.1|refseq:NP_001138481.1|refseq:NP_008979.3|refseq:NP_919423.1|refseq:XP_005248891.1	-	-	-	figure legend:1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.1x10^-6(molar)	2017/03/20	2017/04/21	-	rogid:Qx4k0aSGUrS7rLeSZzv3QJLmM6o9606	-	false	-	his tag:n-n|sufficient binding region:310-513(IPR001870)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16584"	uniprotkb:O00481	intact:EBI-14033603|chebi:"CHEBI:14473"|chebi:"CHEBI:6037"|chebi:"CHEBI:24907"	intact:EBI-2809309|ensembl:ENSP00000289361|uniprotkb:Q147X5|uniprotkb:A2A278|uniprotkb:Q53F15|uniprotkb:Q99420|uniprotkb:Q0P515|uniprotkb:Q9HCY1|uniprotkb:A8K2C8|uniprotkb:B4DIQ1|uniprotkb:E9PHG8|uniprotkb:B4DRM2|uniprotkb:E9PGB4	psi-mi:isopentenyl diphosphate(display_short)|psi-mi:"CHEBI:16584"(display_long)|intact:3-Methyl-3-butenyl pyrophosphate(synonym)|intact:3-methylbut-3-en-1-yl trihydrogen diphosphate(synonym)|intact:3-methylbut-3-enyl phosphono hydrogen phosphate(synonym)|intact:delta-3-Isopentenyl pyrophosphate(synonym)|intact:delta3-isopentenyl diphosphate(synonym)|intact:delta3-Isopentenyl diphosphate(synonym)|intact:delta3-Methyl-3-butenyl diphosphate(synonym)|intact:"Diphosphoric acid mono(3-methyl-3-butenyl) ester"(synonym)|intact:IPP(synonym)|intact:IPPP(synonym)|intact:Isopentenyl diphosphate(synonym)|intact:Isopentenyl pyrophosphate(synonym)|intact:"Mono(3-methyl-3-butenyl) diphosphate"(synonym)|intact:3-methylbut-3-en-1-yl trihydrogen diphosphate(iupac name)	psi-mi:bt3a1_human(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Rhodes et al. (2015)	pubmed:25637025|imex:IM-25688	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14033593|imex:IM-25688-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000026950(gene)|ensembl:ENST00000289361(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037954|interpro:IPR043136|rcsb pdb:4F80|rcsb pdb:4F9L|rcsb pdb:4F9P|rcsb pdb:4JKW|rcsb pdb:4K55|rcsb pdb:4N7I|rcsb pdb:4N7U|rcsb pdb:4V1P|rcsb pdb:5HM7|rcsb pdb:5LYG|rcsb pdb:5LYK|rcsb pdb:5ZXK|rcsb pdb:6ISM|rcsb pdb:6ITA|rcsb pdb:6J06|rcsb pdb:6XLQ|reactome:R-HSA-8851680|refseq:NP_001138480.1|refseq:NP_001138481.1|refseq:NP_008979.3|refseq:NP_919423.1|refseq:XP_005248891.1	-	-	-	figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:627.0x10^-6(molar)	2017/03/20	2017/04/21	-	rogid:Qx4k0aSGUrS7rLeSZzv3QJLmM6o9606	-	false	-	his tag:n-n|sufficient binding region:310-513(IPR001870)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60437	uniprotkb:O00481	intact:EBI-368321|uniprotkb:O60314|uniprotkb:O60454|uniprotkb:Q14C98|intact:EBI-28977702|ensembl:ENSP00000340510	intact:EBI-2809309|ensembl:ENSP00000289361|uniprotkb:Q147X5|uniprotkb:A2A278|uniprotkb:Q53F15|uniprotkb:Q99420|uniprotkb:Q0P515|uniprotkb:Q9HCY1|uniprotkb:A8K2C8|uniprotkb:B4DIQ1|uniprotkb:E9PHG8|uniprotkb:B4DRM2|uniprotkb:E9PGB4	psi-mi:pepl_human(display_long)|uniprotkb:PPL(gene name)|psi-mi:PPL(display_short)|uniprotkb:KIAA0568(gene name synonym)|uniprotkb:195 kDa cornified envelope precursor protein(gene name synonym)|uniprotkb:190 kDa paraneoplastic pemphigus antigen(gene name synonym)	psi-mi:bt3a1_human(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Rhodes et al. (2015)	pubmed:25637025|imex:IM-25688	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14033745|imex:IM-25688-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002696.3|ensembl:ENSP00000340510|ensembl:ENSG00000118898(gene)|ensembl:ENST00000345988(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030057"(desmosome)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR035915|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Q28|reactome:R-HSA-6809371|reactome:R-HSA-8851680|go:"GO:0009612"(response to mechanical stimulus)	ensembl:ENSG00000026950(gene)|ensembl:ENST00000289361(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037954|interpro:IPR043136|rcsb pdb:4F80|rcsb pdb:4F9L|rcsb pdb:4F9P|rcsb pdb:4JKW|rcsb pdb:4K55|rcsb pdb:4N7I|rcsb pdb:4N7U|rcsb pdb:4V1P|rcsb pdb:5HM7|rcsb pdb:5LYG|rcsb pdb:5LYK|rcsb pdb:5ZXK|rcsb pdb:6ISM|rcsb pdb:6ITA|rcsb pdb:6J06|rcsb pdb:6XLQ|reactome:R-HSA-8851680|refseq:NP_001138480.1|refseq:NP_001138481.1|refseq:NP_008979.3|refseq:NP_919423.1|refseq:XP_005248891.1	-	-	-	figure legend:2B, Supp 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.1x10^-6(molar)	2017/03/20	2017/04/21	rogid:z5hpIs1pxsIiWy8S7T5477iRVdg9606	rogid:Qx4k0aSGUrS7rLeSZzv3QJLmM6o9606	rigid:SkOIPqdx59VFIBdQWP54DyFl7io	false	sufficient binding region:133-530|his tag:n-n	his tag:n-n|sufficient binding region:275..275-513|necessary binding region:305-310	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60437	uniprotkb:O00481-2	intact:EBI-368321|uniprotkb:O60314|uniprotkb:O60454|uniprotkb:Q14C98|intact:EBI-28977702|ensembl:ENSP00000340510	intact:EBI-14033666|ensembl:ENSP00000420010	psi-mi:pepl_human(display_long)|uniprotkb:PPL(gene name)|psi-mi:PPL(display_short)|uniprotkb:KIAA0568(gene name synonym)|uniprotkb:195 kDa cornified envelope precursor protein(gene name synonym)|uniprotkb:190 kDa paraneoplastic pemphigus antigen(gene name synonym)	psi-mi:o00481-2(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Rhodes et al. (2015)	pubmed:25637025|imex:IM-25688	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14033841|imex:IM-25688-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002696.3|ensembl:ENSP00000340510|ensembl:ENSG00000118898(gene)|ensembl:ENST00000345988(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030057"(desmosome)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR035915|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Q28|reactome:R-HSA-6809371|reactome:R-HSA-8851680|go:"GO:0009612"(response to mechanical stimulus)	ensembl:ENSG00000026950(gene)|ensembl:ENST00000476549(transcript)|intact:EBI-2809309(isoform-parent)|uniprotkb:O00481-2(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Supp 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:0.58x10^-6(molar)	2017/03/20	2017/04/21	rogid:z5hpIs1pxsIiWy8S7T5477iRVdg9606	rogid:uAVKkDE120OrfpkNph0FlKu9r249606	rigid:YwCRIEqmz9sC0yKH7aNme/75NGI	false	sufficient binding region:133-530|his tag:n-n	his tag:?-?|sufficient binding region:275-352	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60437	uniprotkb:O00481	intact:EBI-368321|uniprotkb:O60314|uniprotkb:O60454|uniprotkb:Q14C98|intact:EBI-28977702|ensembl:ENSP00000340510	intact:EBI-2809309|ensembl:ENSP00000289361|uniprotkb:Q147X5|uniprotkb:A2A278|uniprotkb:Q53F15|uniprotkb:Q99420|uniprotkb:Q0P515|uniprotkb:Q9HCY1|uniprotkb:A8K2C8|uniprotkb:B4DIQ1|uniprotkb:E9PHG8|uniprotkb:B4DRM2|uniprotkb:E9PGB4	psi-mi:pepl_human(display_long)|uniprotkb:PPL(gene name)|psi-mi:PPL(display_short)|uniprotkb:KIAA0568(gene name synonym)|uniprotkb:195 kDa cornified envelope precursor protein(gene name synonym)|uniprotkb:190 kDa paraneoplastic pemphigus antigen(gene name synonym)	psi-mi:bt3a1_human(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Rhodes et al. (2015)	pubmed:25637025|imex:IM-25688	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14033630|imex:IM-25688-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002696.3|ensembl:ENSP00000340510|ensembl:ENSG00000118898(gene)|ensembl:ENST00000345988(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030057"(desmosome)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR035915|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Q28|reactome:R-HSA-6809371|reactome:R-HSA-8851680|go:"GO:0009612"(response to mechanical stimulus)	ensembl:ENSG00000026950(gene)|ensembl:ENST00000289361(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037954|interpro:IPR043136|rcsb pdb:4F80|rcsb pdb:4F9L|rcsb pdb:4F9P|rcsb pdb:4JKW|rcsb pdb:4K55|rcsb pdb:4N7I|rcsb pdb:4N7U|rcsb pdb:4V1P|rcsb pdb:5HM7|rcsb pdb:5LYG|rcsb pdb:5LYK|rcsb pdb:5ZXK|rcsb pdb:6ISM|rcsb pdb:6ITA|rcsb pdb:6J06|rcsb pdb:6XLQ|reactome:R-HSA-8851680|refseq:NP_001138480.1|refseq:NP_001138481.1|refseq:NP_008979.3|refseq:NP_919423.1|refseq:XP_005248891.1	-	-	-	figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/03/20	2017/04/21	rogid:z5hpIs1pxsIiWy8S7T5477iRVdg9606	rogid:Qx4k0aSGUrS7rLeSZzv3QJLmM6o9606	rigid:SkOIPqdx59VFIBdQWP54DyFl7io	false	sufficient binding region:126-657|tag:c-c	sufficient binding region:275..275-513..513	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60437	uniprotkb:O00481	intact:EBI-368321|uniprotkb:O60314|uniprotkb:O60454|uniprotkb:Q14C98|intact:EBI-28977702|ensembl:ENSP00000340510	intact:EBI-2809309|ensembl:ENSP00000289361|uniprotkb:Q147X5|uniprotkb:A2A278|uniprotkb:Q53F15|uniprotkb:Q99420|uniprotkb:Q0P515|uniprotkb:Q9HCY1|uniprotkb:A8K2C8|uniprotkb:B4DIQ1|uniprotkb:E9PHG8|uniprotkb:B4DRM2|uniprotkb:E9PGB4	psi-mi:pepl_human(display_long)|uniprotkb:PPL(gene name)|psi-mi:PPL(display_short)|uniprotkb:KIAA0568(gene name synonym)|uniprotkb:195 kDa cornified envelope precursor protein(gene name synonym)|uniprotkb:190 kDa paraneoplastic pemphigus antigen(gene name synonym)	psi-mi:bt3a1_human(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Rhodes et al. (2015)	pubmed:25637025|imex:IM-25688	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14033651|imex:IM-25688-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002696.3|ensembl:ENSP00000340510|ensembl:ENSG00000118898(gene)|ensembl:ENST00000345988(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030057"(desmosome)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR035915|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Q28|reactome:R-HSA-6809371|reactome:R-HSA-8851680|go:"GO:0009612"(response to mechanical stimulus)	ensembl:ENSG00000026950(gene)|ensembl:ENST00000289361(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037954|interpro:IPR043136|rcsb pdb:4F80|rcsb pdb:4F9L|rcsb pdb:4F9P|rcsb pdb:4JKW|rcsb pdb:4K55|rcsb pdb:4N7I|rcsb pdb:4N7U|rcsb pdb:4V1P|rcsb pdb:5HM7|rcsb pdb:5LYG|rcsb pdb:5LYK|rcsb pdb:5ZXK|rcsb pdb:6ISM|rcsb pdb:6ITA|rcsb pdb:6J06|rcsb pdb:6XLQ|reactome:R-HSA-8851680|refseq:NP_001138480.1|refseq:NP_001138481.1|refseq:NP_008979.3|refseq:NP_919423.1|refseq:XP_005248891.1	-	-	-	figure legend:Supp 1 A/C-3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2017/04/21	rogid:z5hpIs1pxsIiWy8S7T5477iRVdg9606	rogid:Qx4k0aSGUrS7rLeSZzv3QJLmM6o9606	rigid:SkOIPqdx59VFIBdQWP54DyFl7io	false	sufficient binding region:126-657|tag:c-c|xpress tag:?-?	sufficient binding region:275..310-513(IPR001870)|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O60437	uniprotkb:O00481	intact:EBI-368321|uniprotkb:O60314|uniprotkb:O60454|uniprotkb:Q14C98|intact:EBI-28977702|ensembl:ENSP00000340510	intact:EBI-2809309|ensembl:ENSP00000289361|uniprotkb:Q147X5|uniprotkb:A2A278|uniprotkb:Q53F15|uniprotkb:Q99420|uniprotkb:Q0P515|uniprotkb:Q9HCY1|uniprotkb:A8K2C8|uniprotkb:B4DIQ1|uniprotkb:E9PHG8|uniprotkb:B4DRM2|uniprotkb:E9PGB4	psi-mi:pepl_human(display_long)|uniprotkb:PPL(gene name)|psi-mi:PPL(display_short)|uniprotkb:KIAA0568(gene name synonym)|uniprotkb:195 kDa cornified envelope precursor protein(gene name synonym)|uniprotkb:190 kDa paraneoplastic pemphigus antigen(gene name synonym)	psi-mi:bt3a1_human(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Rhodes et al. (2015)	pubmed:25637025|imex:IM-25688	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14033675|imex:IM-25688-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002696.3|ensembl:ENSP00000340510|ensembl:ENSG00000118898(gene)|ensembl:ENST00000345988(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030057"(desmosome)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR035915|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Q28|reactome:R-HSA-6809371|reactome:R-HSA-8851680|go:"GO:0009612"(response to mechanical stimulus)	ensembl:ENSG00000026950(gene)|ensembl:ENST00000289361(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037954|interpro:IPR043136|rcsb pdb:4F80|rcsb pdb:4F9L|rcsb pdb:4F9P|rcsb pdb:4JKW|rcsb pdb:4K55|rcsb pdb:4N7I|rcsb pdb:4N7U|rcsb pdb:4V1P|rcsb pdb:5HM7|rcsb pdb:5LYG|rcsb pdb:5LYK|rcsb pdb:5ZXK|rcsb pdb:6ISM|rcsb pdb:6ITA|rcsb pdb:6J06|rcsb pdb:6XLQ|reactome:R-HSA-8851680|refseq:NP_001138480.1|refseq:NP_001138481.1|refseq:NP_008979.3|refseq:NP_919423.1|refseq:XP_005248891.1	-	-	-	figure legend:Supp 1 A/C-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2017/04/21	rogid:z5hpIs1pxsIiWy8S7T5477iRVdg9606	rogid:Qx4k0aSGUrS7rLeSZzv3QJLmM6o9606	rigid:SkOIPqdx59VFIBdQWP54DyFl7io	false	sufficient binding region:133-530|xpress tag:?-?	sufficient binding region:275..310-513|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O60437	uniprotkb:O00481	intact:EBI-368321|uniprotkb:O60314|uniprotkb:O60454|uniprotkb:Q14C98|intact:EBI-28977702|ensembl:ENSP00000340510	intact:EBI-2809309|ensembl:ENSP00000289361|uniprotkb:Q147X5|uniprotkb:A2A278|uniprotkb:Q53F15|uniprotkb:Q99420|uniprotkb:Q0P515|uniprotkb:Q9HCY1|uniprotkb:A8K2C8|uniprotkb:B4DIQ1|uniprotkb:E9PHG8|uniprotkb:B4DRM2|uniprotkb:E9PGB4	psi-mi:pepl_human(display_long)|uniprotkb:PPL(gene name)|psi-mi:PPL(display_short)|uniprotkb:KIAA0568(gene name synonym)|uniprotkb:195 kDa cornified envelope precursor protein(gene name synonym)|uniprotkb:190 kDa paraneoplastic pemphigus antigen(gene name synonym)	psi-mi:bt3a1_human(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Rhodes et al. (2015)	pubmed:25637025|imex:IM-25688	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14033711|imex:IM-25688-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002696.3|ensembl:ENSP00000340510|ensembl:ENSG00000118898(gene)|ensembl:ENST00000345988(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030057"(desmosome)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR035915|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Q28|reactome:R-HSA-6809371|reactome:R-HSA-8851680|go:"GO:0009612"(response to mechanical stimulus)	ensembl:ENSG00000026950(gene)|ensembl:ENST00000289361(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037954|interpro:IPR043136|rcsb pdb:4F80|rcsb pdb:4F9L|rcsb pdb:4F9P|rcsb pdb:4JKW|rcsb pdb:4K55|rcsb pdb:4N7I|rcsb pdb:4N7U|rcsb pdb:4V1P|rcsb pdb:5HM7|rcsb pdb:5LYG|rcsb pdb:5LYK|rcsb pdb:5ZXK|rcsb pdb:6ISM|rcsb pdb:6ITA|rcsb pdb:6J06|rcsb pdb:6XLQ|reactome:R-HSA-8851680|refseq:NP_001138480.1|refseq:NP_001138481.1|refseq:NP_008979.3|refseq:NP_919423.1|refseq:XP_005248891.1|interpro:IPR001870("B302 (SPRY)-like")	-	-	-	figure legend:Supp 1 A/C-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2017/04/21	rogid:z5hpIs1pxsIiWy8S7T5477iRVdg9606	rogid:Qx4k0aSGUrS7rLeSZzv3QJLmM6o9606	rigid:SkOIPqdx59VFIBdQWP54DyFl7io	false	sufficient binding region:1-495|ha tag:?-?	sufficient binding region:275..310-513|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O60437	uniprotkb:O00481-2	intact:EBI-368321|uniprotkb:O60314|uniprotkb:O60454|uniprotkb:Q14C98|intact:EBI-28977702|ensembl:ENSP00000340510	intact:EBI-14033666|ensembl:ENSP00000420010	psi-mi:pepl_human(display_long)|uniprotkb:PPL(gene name)|psi-mi:PPL(display_short)|uniprotkb:KIAA0568(gene name synonym)|uniprotkb:195 kDa cornified envelope precursor protein(gene name synonym)|uniprotkb:190 kDa paraneoplastic pemphigus antigen(gene name synonym)	psi-mi:o00481-2(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Rhodes et al. (2015)	pubmed:25637025|imex:IM-25688	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14033772|imex:IM-25688-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002696.3|ensembl:ENSP00000340510|ensembl:ENSG00000118898(gene)|ensembl:ENST00000345988(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030057"(desmosome)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR035915|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Q28|reactome:R-HSA-6809371|reactome:R-HSA-8851680|go:"GO:0009612"(response to mechanical stimulus)	ensembl:ENSG00000026950(gene)|ensembl:ENST00000476549(transcript)|intact:EBI-2809309(isoform-parent)|uniprotkb:O00481-2(isoform-parent)|interpro:IPR001870("B302 (SPRY)-like")	-	-	isoform-comment:No experimental confirmation available.	figure legend:Supp 1C-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2017/04/21	rogid:z5hpIs1pxsIiWy8S7T5477iRVdg9606	rogid:uAVKkDE120OrfpkNph0FlKu9r249606	rigid:YwCRIEqmz9sC0yKH7aNme/75NGI	false	sufficient binding region:1-495|ha tag:?-?	sufficient binding region:275-352|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O60437	uniprotkb:O00481-2	intact:EBI-368321|uniprotkb:O60314|uniprotkb:O60454|uniprotkb:Q14C98|intact:EBI-28977702|ensembl:ENSP00000340510	intact:EBI-14033666|ensembl:ENSP00000420010	psi-mi:pepl_human(display_long)|uniprotkb:PPL(gene name)|psi-mi:PPL(display_short)|uniprotkb:KIAA0568(gene name synonym)|uniprotkb:195 kDa cornified envelope precursor protein(gene name synonym)|uniprotkb:190 kDa paraneoplastic pemphigus antigen(gene name synonym)	psi-mi:o00481-2(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Rhodes et al. (2015)	pubmed:25637025|imex:IM-25688	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14033786|imex:IM-25688-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002696.3|ensembl:ENSP00000340510|ensembl:ENSG00000118898(gene)|ensembl:ENST00000345988(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030057"(desmosome)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR035915|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Q28|reactome:R-HSA-6809371|reactome:R-HSA-8851680|go:"GO:0009612"(response to mechanical stimulus)	ensembl:ENSG00000026950(gene)|ensembl:ENST00000476549(transcript)|intact:EBI-2809309(isoform-parent)|uniprotkb:O00481-2(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Supp 1C-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2017/04/21	rogid:z5hpIs1pxsIiWy8S7T5477iRVdg9606	rogid:uAVKkDE120OrfpkNph0FlKu9r249606	rigid:YwCRIEqmz9sC0yKH7aNme/75NGI	false	sufficient binding region:133-530|xpress tag:?-?|necessary binding region:407-495	sufficient binding region:275-352|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O60437	uniprotkb:O00481-2	intact:EBI-368321|uniprotkb:O60314|uniprotkb:O60454|uniprotkb:Q14C98|intact:EBI-28977702|ensembl:ENSP00000340510	intact:EBI-14033666|ensembl:ENSP00000420010	psi-mi:pepl_human(display_long)|uniprotkb:PPL(gene name)|psi-mi:PPL(display_short)|uniprotkb:KIAA0568(gene name synonym)|uniprotkb:195 kDa cornified envelope precursor protein(gene name synonym)|uniprotkb:190 kDa paraneoplastic pemphigus antigen(gene name synonym)	psi-mi:o00481-2(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Rhodes et al. (2015)	pubmed:25637025|imex:IM-25688	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14033804|imex:IM-25688-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002696.3|ensembl:ENSP00000340510|ensembl:ENSG00000118898(gene)|ensembl:ENST00000345988(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030057"(desmosome)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR035915|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Q28|reactome:R-HSA-6809371|reactome:R-HSA-8851680|go:"GO:0009612"(response to mechanical stimulus)	ensembl:ENSG00000026950(gene)|ensembl:ENST00000476549(transcript)|intact:EBI-2809309(isoform-parent)|uniprotkb:O00481-2(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Supp 1C-3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/20	2017/04/21	rogid:z5hpIs1pxsIiWy8S7T5477iRVdg9606	rogid:uAVKkDE120OrfpkNph0FlKu9r249606	rigid:YwCRIEqmz9sC0yKH7aNme/75NGI	false	sufficient binding region:126-657|tag:c-c|xpress tag:?-?	sufficient binding region:275-352(IPR001870)|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O60437	uniprotkb:O00481	intact:EBI-368321|uniprotkb:O60314|uniprotkb:O60454|uniprotkb:Q14C98|intact:EBI-28977702|ensembl:ENSP00000340510	intact:EBI-2809309|ensembl:ENSP00000289361|uniprotkb:Q147X5|uniprotkb:A2A278|uniprotkb:Q53F15|uniprotkb:Q99420|uniprotkb:Q0P515|uniprotkb:Q9HCY1|uniprotkb:A8K2C8|uniprotkb:B4DIQ1|uniprotkb:E9PHG8|uniprotkb:B4DRM2|uniprotkb:E9PGB4	psi-mi:pepl_human(display_long)|uniprotkb:PPL(gene name)|psi-mi:PPL(display_short)|uniprotkb:KIAA0568(gene name synonym)|uniprotkb:195 kDa cornified envelope precursor protein(gene name synonym)|uniprotkb:190 kDa paraneoplastic pemphigus antigen(gene name synonym)	psi-mi:bt3a1_human(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rhodes et al. (2015)	pubmed:25637025|imex:IM-25688	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14033733|imex:IM-25688-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002696.3|ensembl:ENSP00000340510|ensembl:ENSG00000118898(gene)|ensembl:ENST00000345988(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030057"(desmosome)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR035915|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Q28|reactome:R-HSA-6809371|reactome:R-HSA-8851680|go:"GO:0009612"(response to mechanical stimulus)	ensembl:ENSG00000026950(gene)|ensembl:ENST00000289361(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037954|interpro:IPR043136|rcsb pdb:4F80|rcsb pdb:4F9L|rcsb pdb:4F9P|rcsb pdb:4JKW|rcsb pdb:4K55|rcsb pdb:4N7I|rcsb pdb:4N7U|rcsb pdb:4V1P|rcsb pdb:5HM7|rcsb pdb:5LYG|rcsb pdb:5LYK|rcsb pdb:5ZXK|rcsb pdb:6ISM|rcsb pdb:6ITA|rcsb pdb:6J06|rcsb pdb:6XLQ|reactome:R-HSA-8851680|refseq:NP_001138480.1|refseq:NP_001138481.1|refseq:NP_008979.3|refseq:NP_919423.1|refseq:XP_005248891.1	-	-	-	figure legend:2 A/E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/03/20	2017/04/21	rogid:z5hpIs1pxsIiWy8S7T5477iRVdg9606	rogid:Qx4k0aSGUrS7rLeSZzv3QJLmM6o9606	rigid:SkOIPqdx59VFIBdQWP54DyFl7io	false	ha tag:?-?|sufficient binding region:1-495	flag tag:?-?|mutation disrupting interaction strength:308-309	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O60437	uniprotkb:O00481-2	intact:EBI-368321|uniprotkb:O60314|uniprotkb:O60454|uniprotkb:Q14C98|intact:EBI-28977702|ensembl:ENSP00000340510	intact:EBI-14033666|ensembl:ENSP00000420010	psi-mi:pepl_human(display_long)|uniprotkb:PPL(gene name)|psi-mi:PPL(display_short)|uniprotkb:KIAA0568(gene name synonym)|uniprotkb:195 kDa cornified envelope precursor protein(gene name synonym)|uniprotkb:190 kDa paraneoplastic pemphigus antigen(gene name synonym)	psi-mi:o00481-2(display_long)|uniprotkb:BTN3A1(gene name)|psi-mi:BTN3A1(display_short)|uniprotkb:BTF5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rhodes et al. (2015)	pubmed:25637025|imex:IM-25688	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14033819|imex:IM-25688-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002696.3|ensembl:ENSP00000340510|ensembl:ENSG00000118898(gene)|ensembl:ENST00000345988(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030057"(desmosome)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR035915|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Q28|reactome:R-HSA-6809371|reactome:R-HSA-8851680|go:"GO:0009612"(response to mechanical stimulus)	ensembl:ENSG00000026950(gene)|ensembl:ENST00000476549(transcript)|intact:EBI-2809309(isoform-parent)|uniprotkb:O00481-2(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Supp 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/03/20	2017/04/21	rogid:z5hpIs1pxsIiWy8S7T5477iRVdg9606	rogid:uAVKkDE120OrfpkNph0FlKu9r249606	rigid:YwCRIEqmz9sC0yKH7aNme/75NGI	false	ha tag:?-?|sufficient binding region:1-495	v5 tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O60437	uniprotkb:Q13410	intact:EBI-368321|uniprotkb:O60314|uniprotkb:O60454|uniprotkb:Q14C98|intact:EBI-28977702|ensembl:ENSP00000340510	intact:EBI-2372803|uniprotkb:Q4VAN4|uniprotkb:Q9H458|uniprotkb:Q4VAN3|ensembl:ENSP00000244513|ensembl:ENSP00000507193	psi-mi:pepl_human(display_long)|uniprotkb:PPL(gene name)|psi-mi:PPL(display_short)|uniprotkb:KIAA0568(gene name synonym)|uniprotkb:195 kDa cornified envelope precursor protein(gene name synonym)|uniprotkb:190 kDa paraneoplastic pemphigus antigen(gene name synonym)	psi-mi:bt1a1_human(display_long)|uniprotkb:BTN1A1(gene name)|psi-mi:BTN1A1(display_short)|uniprotkb:BTN(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rhodes et al. (2015)	pubmed:25637025|imex:IM-25688	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14033831|imex:IM-25688-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002696.3|ensembl:ENSP00000340510|ensembl:ENSG00000118898(gene)|ensembl:ENST00000345988(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030057"(desmosome)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR035915|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Q28|reactome:R-HSA-6809371|reactome:R-HSA-8851680|go:"GO:0009612"(response to mechanical stimulus)	refseq:NP_001723.2|ensembl:ENSG00000124557(gene)|ensembl:ENST00000244513(transcript)|ensembl:ENST00000684113(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037958|interpro:IPR043136|reactome:R-HSA-8851680	-	-	-	figure legend:Supp 1Di|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/03/20	2017/04/21	rogid:z5hpIs1pxsIiWy8S7T5477iRVdg9606	rogid:3vJxfUEU8CgKp6iDHJvVC/2KNNU9606	rigid:mFtdNEf2DHOYmi9/w2dexNiIehI	false	ha tag:?-?|sufficient binding region:1-495	v5 tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)