#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q969H0	uniprotkb:Q4UG71	intact:EBI-359574|uniprotkb:Q68DR0|uniprotkb:Q96A16|uniprotkb:Q96LE0|uniprotkb:Q96RI2|ensembl:ENSP00000281708|ensembl:ENSP00000474725|ensembl:ENSP00000474971|uniprotkb:Q9NUX6|uniprotkb:B7ZLP9	intact:EBI-16140635	psi-mi:fbxw7_human(display_long)|uniprotkb:FBXW7(gene name)|psi-mi:FBXW7(display_short)|uniprotkb:FBW7(gene name synonym)|uniprotkb:FBX30(gene name synonym)|uniprotkb:SEL10(gene name synonym)|uniprotkb:F-box and WD-40 domain-containing protein 7(gene name synonym)|uniprotkb:F-box protein FBX30(gene name synonym)|uniprotkb:Archipelago homolog(gene name synonym)|uniprotkb:SEL-10(gene name synonym)|uniprotkb:hCdc4(gene name synonym)	psi-mi:pin1_thean(display_long)|uniprotkb:PIN1(gene name)|psi-mi:PIN1(display_short)|uniprotkb:Peptidyl-prolyl cis-trans isomerase Pin1(gene name synonym)|uniprotkb:Rotamase Pin1(gene name synonym)|uniprotkb:TA18945(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Marsolier et al. (2015)	pubmed:25624101|doi:10.1038/nature14044|imex:IM-24415	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:5874(thean)|taxid:5874(Theileria annulata)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16140652|imex:IM-24415-1|dip:DIP-199075E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010868"(negative regulation of triglyceride biosynthetic process)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030324"(lung development)|go:"GO:0030332"(cyclin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|ensembl:ENSG00000109670(gene)|ensembl:ENST00000281708(transcript)|ensembl:ENST00000603548(transcript)|ensembl:ENST00000603841(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001944"(vasculature development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007219"(Notch signaling pathway)|refseq:NP_001013433.1|refseq:NP_060785.2|refseq:NP_361014.1|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090049"(regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903378"(positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000346"(negative regulation of hepatocyte proliferation)|go:"GO:2000639"(negative regulation of SREBP signaling pathway)|go:"GO:2001205"(negative regulation of osteoclast development)|interpro:IPR001680(WD40 repeat)|go:"GO:0050821"(protein stabilization)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:5IBK|rcsb pdb:5V4B|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2894862|reactome:R-HSA-390471|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9604323|reactome:R-HSA-983168|interpro:IPR001810(Cyclin-like F-box)|refseq:XP_011530385.1|refseq:XP_011530386.1|refseq:XP_011530387.1|go:"GO:0050816"(phosphothreonine residue binding)|refseq:XP_016863851.1|dip:DIP-27613N	go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044003"(modulation by symbiont of host process)|interpro:IPR000297(Peptidyl-prolyl cis-trans isomerase, PpiC-type)|refseq:XP_954595.1|dip:DIP-61527N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	-	2017/08/08	2017/08/10	rogid:nTHe/NUeMqEs6y00A9rvRHTUMfk9606	rogid:/NHN8h++RLIwAkzejfxSGNzgNoQ5874	rigid:5KRehRxCgZbwlpzgkcFTB+oRyDM	false	flag tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P62990	uniprotkb:O77627	intact:EBI-413053|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q3T0V5|dip:DIP-29049N	intact:EBI-16140671	psi-mi:ubiq_bovin(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:jun_bovin(display_long)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Marsolier et al. (2015)	pubmed:25624101|doi:10.1038/nature14044|imex:IM-24415	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16140706|imex:IM-24415-2|dip:DIP-199070E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000626(Ubiquitin)|refseq:NP_001069831.1|refseq:NP_777203.1|refseq:NP_776558.1|rcsb pdb:2QHO|rcsb pdb:2ZCC|ensembl:ENSBTAG00000015473|ensembl:ENSBTAG00000017246|rcsb pdb:1E0Q|rcsb pdb:2HD5|rcsb pdb:2OOB|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3H1U|go:"GO:0005515"(protein binding)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|ensembl:ENSBTAG00000007737|rcsb pdb:1AAR|rcsb pdb:1P3Q|rcsb pdb:1UZX|rcsb pdb:1V80|rcsb pdb:1V81|rcsb pdb:1WR6|rcsb pdb:1WRD|rcsb pdb:1YD8|rcsb pdb:2C7M|rcsb pdb:2C7N|rcsb pdb:2D3G|rcsb pdb:2DX5|rcsb pdb:2FID|rcsb pdb:2FIF|go:"GO:0005634"(nucleus)|ipi:IPI00687665|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1	go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR015558(c-Jun Transcription Factor)|dip:DIP-61529N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	-	2017/08/08	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9913	rogid:zqv8uhX8oIkzYNNgZpMvhQ6iLVE9913	rigid:+Q0z82bc1WKvHSmJ7XepgHYh/ME	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13526	uniprotkb:F1MNN4	intact:EBI-714158|uniprotkb:Q53X75|ensembl:ENSP00000247970|ensembl:ENSP00000466962|uniprotkb:A8K4V9	intact:EBI-16140723|ensembl:ENSBTAP00000064414|uniprotkb:Q0VCX6|uniprotkb:A0A3Q1N420	psi-mi:pin1_human(display_long)|uniprotkb:Rotamase Pin1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase Pin1(gene name synonym)|uniprotkb:PIN1(gene name)|psi-mi:PIN1(display_short)	psi-mi:fbxw7_bovin(display_long)|uniprotkb:FBXW7(gene name)|psi-mi:FBXW7(display_short)|uniprotkb:FBW7(gene name synonym)|uniprotkb:F-box and WD-40 domain-containing protein 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marsolier et al. (2015)	pubmed:25624101|doi:10.1038/nature14044|imex:IM-24415	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16140803|imex:IM-24415-5|dip:DIP-199074E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000127445(gene)|ensembl:ENST00000247970(transcript)|ensembl:ENST00000588695(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0016859"(cis-trans isomerase activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:0050808"(synapse organization)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0060393"(regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:2000146"(negative regulation of cell motility)|interpro:IPR000297(Peptidyl-prolyl cis-trans isomerase, PpiC-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR023058|interpro:IPR036020|mint:Q13526|rcsb pdb:1F8A|rcsb pdb:1I6C|rcsb pdb:1I8G|rcsb pdb:1I8H|rcsb pdb:1NMV|rcsb pdb:1NMW|rcsb pdb:1PIN|rcsb pdb:1ZCN|rcsb pdb:2F21|rcsb pdb:2ITK|rcsb pdb:2KBU|rcsb pdb:2KCF|rcsb pdb:2LB3|rcsb pdb:2M8I|rcsb pdb:2M8J|rcsb pdb:2M9E|rcsb pdb:2M9F|rcsb pdb:2M9I|rcsb pdb:2M9J|rcsb pdb:2N1O|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJA|rcsb pdb:7NRK|rcsb pdb:7NRL|reactome:R-HSA-1169408|reactome:R-HSA-5668599|reactome:R-HSA-6804756|reactome:R-HSA-6811555|reactome:R-HSA-936440|rcsb pdb:2RUC|rcsb pdb:2RUD|rcsb pdb:2RUQ|rcsb pdb:2RUR|rcsb pdb:2XP3|rcsb pdb:2XP4|rcsb pdb:2XP5|rcsb pdb:2XP6|rcsb pdb:2XP7|rcsb pdb:2XP8|rcsb pdb:2XP9|rcsb pdb:2XPA|rcsb pdb:2XPB|rcsb pdb:2ZQS|rcsb pdb:2ZQT|rcsb pdb:2ZQU|rcsb pdb:2ZQV|rcsb pdb:2ZR4|rcsb pdb:2Q5A|rcsb pdb:2ZR5|rcsb pdb:2ZR6|rcsb pdb:3I6C|rcsb pdb:4TYO|rcsb pdb:4U84|rcsb pdb:4U85|rcsb pdb:4U86|rcsb pdb:5B3W|rcsb pdb:5B3X|rcsb pdb:5B3Y|rcsb pdb:5B3Z|rcsb pdb:5BMY|rcsb pdb:5GPH|rcsb pdb:5UY9|rcsb pdb:5VTI|rcsb pdb:5VTJ|rcsb pdb:5VTK|rcsb pdb:6DUN|rcsb pdb:6O33|rcsb pdb:6O34|rcsb pdb:6SVC|rcsb pdb:6SVE|rcsb pdb:6SVH|rcsb pdb:6VAJ|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:4TNS|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:3IKD|rcsb pdb:3IKG|rcsb pdb:3JYJ|rcsb pdb:3KAB|rcsb pdb:3KAC|rcsb pdb:3KAD|rcsb pdb:3KAF|rcsb pdb:3KAG|rcsb pdb:3KAH|rcsb pdb:3KAI|rcsb pdb:3KCE|rcsb pdb:3NTP|rcsb pdb:3ODK|rcsb pdb:3OOB|rcsb pdb:3TC5|rcsb pdb:3TCZ|rcsb pdb:3TDB|rcsb pdb:3WH0|rcsb pdb:4GWT|rcsb pdb:4GWV|rcsb pdb:3IK8|rcsb pdb:4QIB|refseq:NP_006212.1|dip:DIP-29306N	ensembl:ENSBTAG00000007953(gene)|ensembl:ENSBTAT00000086850(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|refseq:XP_005217523.1|refseq:XP_005217524.1|refseq:NP_001069717.1|dip:DIP-61528N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	-	2017/08/08	2021/02/12	rogid:FICkSpcBgvSDFW4iY1Etik85xNo9606	rogid:RAYA/2O4NG8+yCcPRPA1RsmsgFQ9913	rigid:Ax3HCSEniZe1qEi+L+e9IaTx3WA	false	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:F1MNN4	uniprotkb:P62990	intact:EBI-16140723|ensembl:ENSBTAP00000064414|uniprotkb:Q0VCX6|uniprotkb:A0A3Q1N420	intact:EBI-413053|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q3T0V5|dip:DIP-29049N	psi-mi:fbxw7_bovin(display_long)|uniprotkb:FBXW7(gene name)|psi-mi:FBXW7(display_short)|uniprotkb:FBW7(gene name synonym)|uniprotkb:F-box and WD-40 domain-containing protein 7(gene name synonym)	psi-mi:ubiq_bovin(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Marsolier et al. (2015)	pubmed:25624101|doi:10.1038/nature14044|imex:IM-24415	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16140786|imex:IM-24415-4|dip:DIP-199071E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSBTAG00000007953(gene)|ensembl:ENSBTAT00000086850(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|refseq:XP_005217523.1|refseq:XP_005217524.1|refseq:NP_001069717.1|dip:DIP-61528N	interpro:IPR000626(Ubiquitin)|refseq:NP_001069831.1|refseq:NP_777203.1|refseq:NP_776558.1|rcsb pdb:2QHO|rcsb pdb:2ZCC|ensembl:ENSBTAG00000015473|ensembl:ENSBTAG00000017246|rcsb pdb:1E0Q|rcsb pdb:2HD5|rcsb pdb:2OOB|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3H1U|go:"GO:0005515"(protein binding)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|ensembl:ENSBTAG00000007737|rcsb pdb:1AAR|rcsb pdb:1P3Q|rcsb pdb:1UZX|rcsb pdb:1V80|rcsb pdb:1V81|rcsb pdb:1WR6|rcsb pdb:1WRD|rcsb pdb:1YD8|rcsb pdb:2C7M|rcsb pdb:2C7N|rcsb pdb:2D3G|rcsb pdb:2DX5|rcsb pdb:2FID|rcsb pdb:2FIF|go:"GO:0005634"(nucleus)|ipi:IPI00687665|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	-	2017/08/08	2021/02/12	rogid:RAYA/2O4NG8+yCcPRPA1RsmsgFQ9913	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9913	rigid:AnrI7AY45KATTOIJaVdAlzLekuA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:F1MNN4	uniprotkb:Q4UG71	intact:EBI-16140723|ensembl:ENSBTAP00000064414|uniprotkb:Q0VCX6|uniprotkb:A0A3Q1N420	intact:EBI-16140635	psi-mi:fbxw7_bovin(display_long)|uniprotkb:FBXW7(gene name)|psi-mi:FBXW7(display_short)|uniprotkb:FBW7(gene name synonym)|uniprotkb:F-box and WD-40 domain-containing protein 7(gene name synonym)	psi-mi:pin1_thean(display_long)|uniprotkb:PIN1(gene name)|psi-mi:PIN1(display_short)|uniprotkb:Peptidyl-prolyl cis-trans isomerase Pin1(gene name synonym)|uniprotkb:Rotamase Pin1(gene name synonym)|uniprotkb:TA18945(orf name)	psi-mi:"MI:0096"(pull down)	Marsolier et al. (2015)	pubmed:25624101|doi:10.1038/nature14044|imex:IM-24415	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:5874(thean)|taxid:5874(Theileria annulata)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16140767|imex:IM-24415-3|dip:DIP-199073E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSBTAG00000007953(gene)|ensembl:ENSBTAT00000086850(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|refseq:XP_005217523.1|refseq:XP_005217524.1|refseq:NP_001069717.1|dip:DIP-61528N	go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044003"(modulation by symbiont of host process)|interpro:IPR000297(Peptidyl-prolyl cis-trans isomerase, PpiC-type)|refseq:XP_954595.1|dip:DIP-61527N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	-	2017/08/08	2021/02/12	rogid:RAYA/2O4NG8+yCcPRPA1RsmsgFQ9913	rogid:/NHN8h++RLIwAkzejfxSGNzgNoQ5874	rigid:g/oGdWdf0/xhqPF9QlMGnXR0/kY	false	-	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8VBV4	uniprotkb:Q4UG71	intact:EBI-8508250|uniprotkb:D3YUA5|uniprotkb:Q8CCS5|uniprotkb:Q8VHP4|uniprotkb:A2RRI5|intact:MINT-4609106|ensembl:ENSMUSP00000103305|ensembl:ENSMUSP00000103306	intact:EBI-16140635	psi-mi:fbxw7_mouse(display_long)|uniprotkb:Fbxw7(gene name)|psi-mi:Fbxw7(display_short)|uniprotkb:Fbw7(gene name synonym)|uniprotkb:Fbwd6(gene name synonym)|uniprotkb:Fbxw6(gene name synonym)|uniprotkb:F-box and WD-40 domain-containing protein 7(gene name synonym)|uniprotkb:F-box protein FBW7(gene name synonym)|uniprotkb:F-box protein Fbxw6(gene name synonym)|uniprotkb:F-box-WD40 repeat protein 6(gene name synonym)|uniprotkb:SEL-10(gene name synonym)	psi-mi:pin1_thean(display_long)|uniprotkb:PIN1(gene name)|psi-mi:PIN1(display_short)|uniprotkb:Peptidyl-prolyl cis-trans isomerase Pin1(gene name synonym)|uniprotkb:Rotamase Pin1(gene name synonym)|uniprotkb:TA18945(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Marsolier et al. (2015)	pubmed:25624101|doi:10.1038/nature14044|imex:IM-24415	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:5874(thean)|taxid:5874(Theileria annulata)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16140822|imex:IM-24415-6|dip:DIP-199072E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006501719.1|refseq:XP_006501720.1|refseq:NP_536353.2|refseq:NP_001171244.1|refseq:NP_001171245.1|dip:DIP-61083N|ensembl:ENSMUSG00000028086(gene)|ensembl:ENSMUST00000107678(transcript)|ensembl:ENSMUST00000107679(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030324"(lung development)|go:"GO:0030332"(cyclin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090049"(regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903378"(positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001205"(negative regulation of osteoclast development)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|reactome:R-MMU-8951664|reactome:R-MMU-983168	go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044003"(modulation by symbiont of host process)|interpro:IPR000297(Peptidyl-prolyl cis-trans isomerase, PpiC-type)|refseq:XP_954595.1|dip:DIP-61527N	psi-mi:"MI:0465"(dip)	function:"Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1"|comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/08	2018/04/30	rogid:uwQpYjPu79fWAN47k2nAxkvuDbo10090	rogid:/NHN8h++RLIwAkzejfxSGNzgNoQ5874	rigid:Y59PXeTGh1zU0JZmCqJFFmhPEzs	false	-	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)