#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q96NB3	uniprotkb:O60306	intact:EBI-3920997|ensembl:ENSP00000354518|uniprotkb:Q96F60|uniprotkb:Q96GZ5|uniprotkb:Q9BU38	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	psi-mi:zn830_human(display_long)|uniprotkb:ZNF830(gene name)|psi-mi:ZNF830(display_short)|uniprotkb:CCDC16(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 16(gene name synonym)	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139256|imex:IM-24432-1|dip:DIP-199115E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198783(gene)|ensembl:ENST00000361952(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001546"(preantral ovarian follicle growth)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060729"(intestinal epithelial structure maintenance)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR036236|interpro:IPR040050|mint:Q96NB3|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|refseq:NP_443089.3|dip:DIP-61544N	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:4PbBUxZP6ipr8qKoU7JWlkldInE9606	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rigid:6kKlAF8jCCPZHHLjUqjwQqSMFL0	false	crosslinked residues:83-83	crosslinked residues:1045-1045	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9ULR0	uniprotkb:O60306	intact:EBI-2557660|uniprotkb:Q9BT05|uniprotkb:Q96IL2|ensembl:ENSP00000376973	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	psi-mi:isy1_human(display_long)|uniprotkb:ISY1(gene name)|psi-mi:ISY1(display_short)|uniprotkb:KIAA1160(gene name synonym)	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139299|imex:IM-24432-3|dip:DIP-199116E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186398.1|refseq:NP_001191819.1|refseq:NP_065752.1|dip:DIP-56636N|ensembl:ENSG00000240682(gene)|ensembl:ENST00000393295(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071020"(post-spliceosomal complex)|interpro:IPR009360(Isy1-like splicing)|interpro:IPR029012|interpro:IPR037200|mint:Q9ULR0|rcsb pdb:5YZG|rcsb pdb:6FF7|rcsb pdb:6ZYM|rcsb pdb:7A5P|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:t4QKu0uotUIJIzR8DTXWje21U1A9606	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rigid:YgWjEWZaojfzOVB97Rfkys+WABI	false	crosslinked residues:266-266	crosslinked residues:37-37	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60306	uniprotkb:Q9ULR0	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	intact:EBI-2557660|uniprotkb:Q9BT05|uniprotkb:Q96IL2|ensembl:ENSP00000376973	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:isy1_human(display_long)|uniprotkb:ISY1(gene name)|psi-mi:ISY1(display_short)|uniprotkb:KIAA1160(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139277|imex:IM-24432-2|dip:DIP-199114E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	refseq:NP_001186398.1|refseq:NP_001191819.1|refseq:NP_065752.1|dip:DIP-56636N|ensembl:ENSG00000240682(gene)|ensembl:ENST00000393295(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071020"(post-spliceosomal complex)|interpro:IPR009360(Isy1-like splicing)|interpro:IPR029012|interpro:IPR037200|mint:Q9ULR0|rcsb pdb:5YZG|rcsb pdb:6FF7|rcsb pdb:6ZYM|rcsb pdb:7A5P|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rogid:t4QKu0uotUIJIzR8DTXWje21U1A9606	rigid:80DJaNqNPz043LpM1Ab12l3MffQ	false	necessary binding region:1-416	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:O60306	uniprotkb:Q9UNP9	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139277|imex:IM-24432-2|dip:DIP-199114E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606	rigid:80DJaNqNPz043LpM1Ab12l3MffQ	false	necessary binding region:1-416	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:O60306	uniprotkb:Q9HCS7	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	intact:EBI-295232|uniprotkb:Q8TET6|uniprotkb:Q96HB0|uniprotkb:Q96IW0|uniprotkb:Q9NRG6|uniprotkb:Q9ULP3|ensembl:ENSP00000351137	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:syf1_human(display_long)|uniprotkb:XAB2(gene name)|psi-mi:XAB2(display_short)|uniprotkb:HCNP(gene name synonym)|uniprotkb:KIAA1177(gene name synonym)|uniprotkb:PP3898(orf name)|uniprotkb:SYF1(gene name synonym)|uniprotkb:XPA-binding protein 2(gene name synonym)|uniprotkb:Protein HCNP(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139277|imex:IM-24432-2|dip:DIP-199114E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	refseq:NP_064581.2|dip:DIP-31646N|ensembl:ENSG00000076924(gene)|ensembl:ENST00000358368(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016020"(membrane)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9HCS7|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rogid:6+Vu8QmYaVK/kd5ADY6uaUY35SQ9606	rigid:80DJaNqNPz043LpM1Ab12l3MffQ	false	necessary binding region:1-416	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:O60306	uniprotkb:Q96NB3	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	intact:EBI-3920997|ensembl:ENSP00000354518|uniprotkb:Q96F60|uniprotkb:Q96GZ5|uniprotkb:Q9BU38	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:zn830_human(display_long)|uniprotkb:ZNF830(gene name)|psi-mi:ZNF830(display_short)|uniprotkb:CCDC16(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 16(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139277|imex:IM-24432-2|dip:DIP-199114E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	ensembl:ENSG00000198783(gene)|ensembl:ENST00000361952(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001546"(preantral ovarian follicle growth)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060729"(intestinal epithelial structure maintenance)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR036236|interpro:IPR040050|mint:Q96NB3|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|refseq:NP_443089.3|dip:DIP-61544N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rogid:4PbBUxZP6ipr8qKoU7JWlkldInE9606	rigid:80DJaNqNPz043LpM1Ab12l3MffQ	false	necessary binding region:1-416	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9HCS7	uniprotkb:P09661	intact:EBI-295232|uniprotkb:Q8TET6|uniprotkb:Q96HB0|uniprotkb:Q96IW0|uniprotkb:Q9NRG6|uniprotkb:Q9ULP3|ensembl:ENSP00000351137	intact:EBI-876439|uniprotkb:Q8TBD2|uniprotkb:B2R5I6|ensembl:ENSP00000254193	psi-mi:syf1_human(display_long)|uniprotkb:XAB2(gene name)|psi-mi:XAB2(display_short)|uniprotkb:HCNP(gene name synonym)|uniprotkb:KIAA1177(gene name synonym)|uniprotkb:PP3898(orf name)|uniprotkb:SYF1(gene name synonym)|uniprotkb:XPA-binding protein 2(gene name synonym)|uniprotkb:Protein HCNP(gene name synonym)	psi-mi:ru2a_human(display_long)|uniprotkb:SNRPA1(gene name)|psi-mi:SNRPA1(display_short)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139383|imex:IM-24432-7|dip:DIP-199125E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064581.2|dip:DIP-31646N|ensembl:ENSG00000076924(gene)|ensembl:ENST00000358368(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016020"(membrane)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9HCS7|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163	refseq:NP_003081.2|dip:DIP-625N|ensembl:ENSG00000131876(gene)|ensembl:ENST00000254193(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR044640|mint:P09661|rcsb pdb:1A9N|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|reactome:R-HSA-8950505	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:6+Vu8QmYaVK/kd5ADY6uaUY35SQ9606	rogid:tmZyAPCvMg34GY4kVc6NcnycOeE9606	rigid:y5rYeXKYCe77G6gUxOozTNt1tu4	false	crosslinked residues:2-2	crosslinked residues:205-205	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HCS7	uniprotkb:O60306	intact:EBI-295232|uniprotkb:Q8TET6|uniprotkb:Q96HB0|uniprotkb:Q96IW0|uniprotkb:Q9NRG6|uniprotkb:Q9ULP3|ensembl:ENSP00000351137	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	psi-mi:syf1_human(display_long)|uniprotkb:XAB2(gene name)|psi-mi:XAB2(display_short)|uniprotkb:HCNP(gene name synonym)|uniprotkb:KIAA1177(gene name synonym)|uniprotkb:PP3898(orf name)|uniprotkb:SYF1(gene name synonym)|uniprotkb:XPA-binding protein 2(gene name synonym)|uniprotkb:Protein HCNP(gene name synonym)	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139404|imex:IM-24432-8|dip:DIP-199117E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064581.2|dip:DIP-31646N|ensembl:ENSG00000076924(gene)|ensembl:ENST00000358368(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016020"(membrane)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9HCS7|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:6+Vu8QmYaVK/kd5ADY6uaUY35SQ9606	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rigid:49GXNYnqK1pnig0X5u0qwhtOy0w	false	crosslinked residues:62-62	crosslinked residues:950-950	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60306	uniprotkb:Q9ULR0	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	intact:EBI-2557660|uniprotkb:Q9BT05|uniprotkb:Q96IL2|ensembl:ENSP00000376973	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:isy1_human(display_long)|uniprotkb:ISY1(gene name)|psi-mi:ISY1(display_short)|uniprotkb:KIAA1160(gene name synonym)	psi-mi:"MI:0067"(light scattering)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139427|imex:IM-24432-9|dip:DIP-199114E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	refseq:NP_001186398.1|refseq:NP_001191819.1|refseq:NP_065752.1|dip:DIP-56636N|ensembl:ENSG00000240682(gene)|ensembl:ENST00000393295(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071020"(post-spliceosomal complex)|interpro:IPR009360(Isy1-like splicing)|interpro:IPR029012|interpro:IPR037200|mint:Q9ULR0|rcsb pdb:5YZG|rcsb pdb:6FF7|rcsb pdb:6ZYM|rcsb pdb:7A5P|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rogid:t4QKu0uotUIJIzR8DTXWje21U1A9606	rigid:80DJaNqNPz043LpM1Ab12l3MffQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60306	uniprotkb:Q9UNP9	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym)	psi-mi:"MI:0067"(light scattering)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139427|imex:IM-24432-9|dip:DIP-199114E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606	rigid:80DJaNqNPz043LpM1Ab12l3MffQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60306	uniprotkb:Q9HCS7	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	intact:EBI-295232|uniprotkb:Q8TET6|uniprotkb:Q96HB0|uniprotkb:Q96IW0|uniprotkb:Q9NRG6|uniprotkb:Q9ULP3|ensembl:ENSP00000351137	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:syf1_human(display_long)|uniprotkb:XAB2(gene name)|psi-mi:XAB2(display_short)|uniprotkb:HCNP(gene name synonym)|uniprotkb:KIAA1177(gene name synonym)|uniprotkb:PP3898(orf name)|uniprotkb:SYF1(gene name synonym)|uniprotkb:XPA-binding protein 2(gene name synonym)|uniprotkb:Protein HCNP(gene name synonym)	psi-mi:"MI:0067"(light scattering)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139427|imex:IM-24432-9|dip:DIP-199114E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	refseq:NP_064581.2|dip:DIP-31646N|ensembl:ENSG00000076924(gene)|ensembl:ENST00000358368(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016020"(membrane)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9HCS7|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rogid:6+Vu8QmYaVK/kd5ADY6uaUY35SQ9606	rigid:80DJaNqNPz043LpM1Ab12l3MffQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60306	uniprotkb:Q96NB3	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	intact:EBI-3920997|ensembl:ENSP00000354518|uniprotkb:Q96F60|uniprotkb:Q96GZ5|uniprotkb:Q9BU38	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:zn830_human(display_long)|uniprotkb:ZNF830(gene name)|psi-mi:ZNF830(display_short)|uniprotkb:CCDC16(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 16(gene name synonym)	psi-mi:"MI:0067"(light scattering)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139427|imex:IM-24432-9|dip:DIP-199114E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	ensembl:ENSG00000198783(gene)|ensembl:ENST00000361952(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001546"(preantral ovarian follicle growth)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060729"(intestinal epithelial structure maintenance)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR036236|interpro:IPR040050|mint:Q96NB3|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|refseq:NP_443089.3|dip:DIP-61544N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rogid:4PbBUxZP6ipr8qKoU7JWlkldInE9606	rigid:80DJaNqNPz043LpM1Ab12l3MffQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UNP9	uniprotkb:O60306	intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym)	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139447|imex:IM-24432-10|dip:DIP-199118E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rigid:W5ouZ/6F9aQ/keT2I7Xjj4Tu0fY	false	crosslinked residues:123-123	crosslinked residues:604-604	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96NB3	uniprotkb:O60306	intact:EBI-3920997|ensembl:ENSP00000354518|uniprotkb:Q96F60|uniprotkb:Q96GZ5|uniprotkb:Q9BU38	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	psi-mi:zn830_human(display_long)|uniprotkb:ZNF830(gene name)|psi-mi:ZNF830(display_short)|uniprotkb:CCDC16(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 16(gene name synonym)	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139362|imex:IM-24432-6|dip:DIP-199115E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198783(gene)|ensembl:ENST00000361952(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001546"(preantral ovarian follicle growth)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060729"(intestinal epithelial structure maintenance)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR036236|interpro:IPR040050|mint:Q96NB3|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|refseq:NP_443089.3|dip:DIP-61544N	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:4PbBUxZP6ipr8qKoU7JWlkldInE9606	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rigid:6kKlAF8jCCPZHHLjUqjwQqSMFL0	false	crosslinked residues:117-117	crosslinked residues:604-604	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15393	uniprotkb:Q96NB3	intact:EBI-346977|uniprotkb:Q6NTI8|uniprotkb:Q96GC0|uniprotkb:Q9BPY2|uniprotkb:Q9UFX7|uniprotkb:Q9UJ29|ensembl:ENSP00000305790	intact:EBI-3920997|ensembl:ENSP00000354518|uniprotkb:Q96F60|uniprotkb:Q96GZ5|uniprotkb:Q9BU38	psi-mi:sf3b3_human(display_long)|uniprotkb:SF3B3(gene name)|psi-mi:SF3B3(display_short)|uniprotkb:KIAA0017(gene name synonym)|uniprotkb:SAP130(gene name synonym)|uniprotkb:Spliceosome-associated protein 130(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 130 kDa subunit(gene name synonym)|uniprotkb:STAF130(gene name synonym)	psi-mi:zn830_human(display_long)|uniprotkb:ZNF830(gene name)|psi-mi:ZNF830(display_short)|uniprotkb:CCDC16(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 16(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139341|imex:IM-24432-5|dip:DIP-199122E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036558.3|dip:DIP-28152N|ensembl:ENSG00000189091(gene)|ensembl:ENST00000302516(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|rcsb pdb:5O9Z|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|go:"GO:0005730"(nucleolus)|go:"GO:0008380"(RNA splicing)|rcsb pdb:5ZYA|rcsb pdb:6AH0|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR036322|mint:Q15393|rcsb pdb:5IFE	ensembl:ENSG00000198783(gene)|ensembl:ENST00000361952(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001546"(preantral ovarian follicle growth)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060729"(intestinal epithelial structure maintenance)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR036236|interpro:IPR040050|mint:Q96NB3|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|refseq:NP_443089.3|dip:DIP-61544N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:gnCSXjZ/bwNXair6kyQUKoKIwbM9606	rogid:4PbBUxZP6ipr8qKoU7JWlkldInE9606	rigid:IJNHAFzxeNJGJlRiB6+vMnfjwig	false	crosslinked residues:980-980	crosslinked residues:343-343	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UNP9	uniprotkb:O60306	intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym)	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139320|imex:IM-24432-4|dip:DIP-199118E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rigid:W5ouZ/6F9aQ/keT2I7Xjj4Tu0fY	false	crosslinked residues:88-88	crosslinked residues:1234-1234	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60306	uniprotkb:Q9ULR0	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	intact:EBI-2557660|uniprotkb:Q9BT05|uniprotkb:Q96IL2|ensembl:ENSP00000376973	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:isy1_human(display_long)|uniprotkb:ISY1(gene name)|psi-mi:ISY1(display_short)|uniprotkb:KIAA1160(gene name synonym)	psi-mi:"MI:0226"(ion exchange chromatography)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139468|imex:IM-24432-11|dip:DIP-199114E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	refseq:NP_001186398.1|refseq:NP_001191819.1|refseq:NP_065752.1|dip:DIP-56636N|ensembl:ENSG00000240682(gene)|ensembl:ENST00000393295(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071020"(post-spliceosomal complex)|interpro:IPR009360(Isy1-like splicing)|interpro:IPR029012|interpro:IPR037200|mint:Q9ULR0|rcsb pdb:5YZG|rcsb pdb:6FF7|rcsb pdb:6ZYM|rcsb pdb:7A5P|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rogid:t4QKu0uotUIJIzR8DTXWje21U1A9606	rigid:80DJaNqNPz043LpM1Ab12l3MffQ	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:O60306	uniprotkb:Q9UNP9	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym)	psi-mi:"MI:0226"(ion exchange chromatography)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139468|imex:IM-24432-11|dip:DIP-199114E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606	rigid:80DJaNqNPz043LpM1Ab12l3MffQ	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:O60306	uniprotkb:Q9HCS7	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	intact:EBI-295232|uniprotkb:Q8TET6|uniprotkb:Q96HB0|uniprotkb:Q96IW0|uniprotkb:Q9NRG6|uniprotkb:Q9ULP3|ensembl:ENSP00000351137	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:syf1_human(display_long)|uniprotkb:XAB2(gene name)|psi-mi:XAB2(display_short)|uniprotkb:HCNP(gene name synonym)|uniprotkb:KIAA1177(gene name synonym)|uniprotkb:PP3898(orf name)|uniprotkb:SYF1(gene name synonym)|uniprotkb:XPA-binding protein 2(gene name synonym)|uniprotkb:Protein HCNP(gene name synonym)	psi-mi:"MI:0226"(ion exchange chromatography)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139468|imex:IM-24432-11|dip:DIP-199114E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	refseq:NP_064581.2|dip:DIP-31646N|ensembl:ENSG00000076924(gene)|ensembl:ENST00000358368(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016020"(membrane)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9HCS7|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rogid:6+Vu8QmYaVK/kd5ADY6uaUY35SQ9606	rigid:80DJaNqNPz043LpM1Ab12l3MffQ	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:O60306	uniprotkb:Q96NB3	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	intact:EBI-3920997|ensembl:ENSP00000354518|uniprotkb:Q96F60|uniprotkb:Q96GZ5|uniprotkb:Q9BU38	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:zn830_human(display_long)|uniprotkb:ZNF830(gene name)|psi-mi:ZNF830(display_short)|uniprotkb:CCDC16(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 16(gene name synonym)	psi-mi:"MI:0226"(ion exchange chromatography)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139468|imex:IM-24432-11|dip:DIP-199114E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	ensembl:ENSG00000198783(gene)|ensembl:ENST00000361952(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001546"(preantral ovarian follicle growth)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060729"(intestinal epithelial structure maintenance)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR036236|interpro:IPR040050|mint:Q96NB3|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|refseq:NP_443089.3|dip:DIP-61544N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rogid:4PbBUxZP6ipr8qKoU7JWlkldInE9606	rigid:80DJaNqNPz043LpM1Ab12l3MffQ	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q15428	uniprotkb:Q9UNP9	intact:EBI-2462271|uniprotkb:O75245|uniprotkb:B2RBU1|uniprotkb:D6W605|intact:EBI-28985293|ensembl:ENSP00000221494	intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769	psi-mi:sf3a2_human(display_long)|uniprotkb:SF3A2(gene name)|psi-mi:SF3A2(display_short)|uniprotkb:SAP62(gene name synonym)|uniprotkb:Spliceosome-associated protein 62(gene name synonym)|uniprotkb:SF3a66(gene name synonym)	psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139488|imex:IM-24432-12|dip:DIP-199121E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009096.2|ensembl:ENSP00000221494|dip:DIP-42521N|ensembl:ENSG00000104897(gene)|ensembl:ENST00000221494(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016607"(nuclear speck)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR031781|interpro:IPR036236|mint:Q15428|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|reactome:R-HSA-72163	refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ME4xzpqT37HjPl/xy683FS1Vns89606	rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606	rigid:OHALa7hjDLYv5DixyRiA2p1SYFw	false	crosslinked residues:88-88	crosslinked residues:83-83	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96NB3	uniprotkb:O60306	intact:EBI-3920997|ensembl:ENSP00000354518|uniprotkb:Q96F60|uniprotkb:Q96GZ5|uniprotkb:Q9BU38	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	psi-mi:zn830_human(display_long)|uniprotkb:ZNF830(gene name)|psi-mi:ZNF830(display_short)|uniprotkb:CCDC16(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 16(gene name synonym)	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139509|imex:IM-24432-13|dip:DIP-199115E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198783(gene)|ensembl:ENST00000361952(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001546"(preantral ovarian follicle growth)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060729"(intestinal epithelial structure maintenance)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR036236|interpro:IPR040050|mint:Q96NB3|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|refseq:NP_443089.3|dip:DIP-61544N	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:4PbBUxZP6ipr8qKoU7JWlkldInE9606	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rigid:6kKlAF8jCCPZHHLjUqjwQqSMFL0	false	crosslinked residues:320-320	crosslinked residues:762-762	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UNP9	uniprotkb:O60306	intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym)	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139530|imex:IM-24432-14|dip:DIP-199118E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rigid:W5ouZ/6F9aQ/keT2I7Xjj4Tu0fY	false	crosslinked residues:88-88	crosslinked residues:1104-1104	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15459	uniprotkb:Q9UNP9	intact:EBI-1054743|uniprotkb:E9PAW1|ensembl:ENSP00000215793	intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769	psi-mi:sf3a1_human(display_long)|uniprotkb:Spliceosome-associated protein 114(gene name synonym)|uniprotkb:SF3a120(gene name synonym)|uniprotkb:SF3A1(gene name)|psi-mi:SF3A1(display_short)|uniprotkb:SAP114(gene name synonym)	psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139551|imex:IM-24432-15|dip:DIP-199120E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005868.1|ensembl:ENSG00000099995(gene)|ensembl:ENST00000215793(transcript)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|rcsb pdb:2DT6|go:"GO:0071004"(U2-type prespliceosome)|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6QX9|go:"GO:0071005"(U2-type precatalytic spliceosome)|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|interpro:IPR029071|interpro:IPR035563|interpro:IPR035967|mint:Q15459|rcsb pdb:1ZKH|dip:DIP-29164N	refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:YrIs3RwfjUcDsHCJDgTLMnOUJZM9606	rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606	rigid:LKmu3yB+GwL7+u7dt9IZNqCt+Z4	false	crosslinked residues:2-2	crosslinked residues:218-218	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P09661	uniprotkb:Q9ULR0	intact:EBI-876439|uniprotkb:Q8TBD2|uniprotkb:B2R5I6|ensembl:ENSP00000254193	intact:EBI-2557660|uniprotkb:Q9BT05|uniprotkb:Q96IL2|ensembl:ENSP00000376973	psi-mi:ru2a_human(display_long)|uniprotkb:SNRPA1(gene name)|psi-mi:SNRPA1(display_short)	psi-mi:isy1_human(display_long)|uniprotkb:ISY1(gene name)|psi-mi:ISY1(display_short)|uniprotkb:KIAA1160(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139572|imex:IM-24432-16|dip:DIP-199124E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003081.2|dip:DIP-625N|ensembl:ENSG00000131876(gene)|ensembl:ENST00000254193(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR044640|mint:P09661|rcsb pdb:1A9N|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|reactome:R-HSA-8950505	refseq:NP_001186398.1|refseq:NP_001191819.1|refseq:NP_065752.1|dip:DIP-56636N|ensembl:ENSG00000240682(gene)|ensembl:ENST00000393295(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071020"(post-spliceosomal complex)|interpro:IPR009360(Isy1-like splicing)|interpro:IPR029012|interpro:IPR037200|mint:Q9ULR0|rcsb pdb:5YZG|rcsb pdb:6FF7|rcsb pdb:6ZYM|rcsb pdb:7A5P|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:tmZyAPCvMg34GY4kVc6NcnycOeE9606	rogid:t4QKu0uotUIJIzR8DTXWje21U1A9606	rigid:vNFv0Wlol+ptkWXGUpaOBhyyPF8	false	crosslinked residues:193-193	crosslinked residues:264-264	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96NB3	uniprotkb:O60306	intact:EBI-3920997|ensembl:ENSP00000354518|uniprotkb:Q96F60|uniprotkb:Q96GZ5|uniprotkb:Q9BU38	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	psi-mi:zn830_human(display_long)|uniprotkb:ZNF830(gene name)|psi-mi:ZNF830(display_short)|uniprotkb:CCDC16(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 16(gene name synonym)	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139593|imex:IM-24432-17|dip:DIP-199115E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198783(gene)|ensembl:ENST00000361952(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001546"(preantral ovarian follicle growth)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060729"(intestinal epithelial structure maintenance)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR036236|interpro:IPR040050|mint:Q96NB3|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|refseq:NP_443089.3|dip:DIP-61544N	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:4PbBUxZP6ipr8qKoU7JWlkldInE9606	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rigid:6kKlAF8jCCPZHHLjUqjwQqSMFL0	false	crosslinked residues:140-140	crosslinked residues:1256-1256	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9ULR0	uniprotkb:O60306	intact:EBI-2557660|uniprotkb:Q9BT05|uniprotkb:Q96IL2|ensembl:ENSP00000376973	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	psi-mi:isy1_human(display_long)|uniprotkb:ISY1(gene name)|psi-mi:ISY1(display_short)|uniprotkb:KIAA1160(gene name synonym)	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139614|imex:IM-24432-18|dip:DIP-199116E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186398.1|refseq:NP_001191819.1|refseq:NP_065752.1|dip:DIP-56636N|ensembl:ENSG00000240682(gene)|ensembl:ENST00000393295(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071020"(post-spliceosomal complex)|interpro:IPR009360(Isy1-like splicing)|interpro:IPR029012|interpro:IPR037200|mint:Q9ULR0|rcsb pdb:5YZG|rcsb pdb:6FF7|rcsb pdb:6ZYM|rcsb pdb:7A5P|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:t4QKu0uotUIJIzR8DTXWje21U1A9606	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rigid:YgWjEWZaojfzOVB97Rfkys+WABI	false	crosslinked residues:101-101	crosslinked residues:604-604	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60306	uniprotkb:Q9UNP9	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym)	psi-mi:"MI:0096"(pull down)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139635|imex:IM-24432-19|dip:DIP-199114E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606	rigid:80DJaNqNPz043LpM1Ab12l3MffQ	false	necessary binding region:1-416|his tag:n-n	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:O60306	uniprotkb:Q9ULR0	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	intact:EBI-2557660|uniprotkb:Q9BT05|uniprotkb:Q96IL2|ensembl:ENSP00000376973	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:isy1_human(display_long)|uniprotkb:ISY1(gene name)|psi-mi:ISY1(display_short)|uniprotkb:KIAA1160(gene name synonym)	psi-mi:"MI:0096"(pull down)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139635|imex:IM-24432-19|dip:DIP-199114E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	refseq:NP_001186398.1|refseq:NP_001191819.1|refseq:NP_065752.1|dip:DIP-56636N|ensembl:ENSG00000240682(gene)|ensembl:ENST00000393295(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071020"(post-spliceosomal complex)|interpro:IPR009360(Isy1-like splicing)|interpro:IPR029012|interpro:IPR037200|mint:Q9ULR0|rcsb pdb:5YZG|rcsb pdb:6FF7|rcsb pdb:6ZYM|rcsb pdb:7A5P|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rogid:t4QKu0uotUIJIzR8DTXWje21U1A9606	rigid:80DJaNqNPz043LpM1Ab12l3MffQ	false	necessary binding region:1-416|his tag:n-n	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:O60306	uniprotkb:Q96NB3	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	intact:EBI-3920997|ensembl:ENSP00000354518|uniprotkb:Q96F60|uniprotkb:Q96GZ5|uniprotkb:Q9BU38	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:zn830_human(display_long)|uniprotkb:ZNF830(gene name)|psi-mi:ZNF830(display_short)|uniprotkb:CCDC16(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 16(gene name synonym)	psi-mi:"MI:0096"(pull down)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139635|imex:IM-24432-19|dip:DIP-199114E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	ensembl:ENSG00000198783(gene)|ensembl:ENST00000361952(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001546"(preantral ovarian follicle growth)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060729"(intestinal epithelial structure maintenance)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR036236|interpro:IPR040050|mint:Q96NB3|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|refseq:NP_443089.3|dip:DIP-61544N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rogid:4PbBUxZP6ipr8qKoU7JWlkldInE9606	rigid:80DJaNqNPz043LpM1Ab12l3MffQ	false	necessary binding region:1-416|his tag:n-n	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:O60306	uniprotkb:Q9HCS7	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	intact:EBI-295232|uniprotkb:Q8TET6|uniprotkb:Q96HB0|uniprotkb:Q96IW0|uniprotkb:Q9NRG6|uniprotkb:Q9ULP3|ensembl:ENSP00000351137	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:syf1_human(display_long)|uniprotkb:XAB2(gene name)|psi-mi:XAB2(display_short)|uniprotkb:HCNP(gene name synonym)|uniprotkb:KIAA1177(gene name synonym)|uniprotkb:PP3898(orf name)|uniprotkb:SYF1(gene name synonym)|uniprotkb:XPA-binding protein 2(gene name synonym)|uniprotkb:Protein HCNP(gene name synonym)	psi-mi:"MI:0096"(pull down)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139635|imex:IM-24432-19|dip:DIP-199114E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	refseq:NP_064581.2|dip:DIP-31646N|ensembl:ENSG00000076924(gene)|ensembl:ENST00000358368(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016020"(membrane)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9HCS7|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rogid:6+Vu8QmYaVK/kd5ADY6uaUY35SQ9606	rigid:80DJaNqNPz043LpM1Ab12l3MffQ	false	necessary binding region:1-416|his tag:n-n	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9UNP9	uniprotkb:O60306	intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym)	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139659|imex:IM-24432-20|dip:DIP-199118E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rigid:W5ouZ/6F9aQ/keT2I7Xjj4Tu0fY	false	crosslinked residues:114-114	crosslinked residues:1025-1025	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75533-1	uniprotkb:O60306	intact:EBI-15565798|ensembl:ENSP00000335321	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	psi-mi:o75533-1(display_long)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym)	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139680|imex:IM-24432-21|dip:DIP-199119E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-876542(isoform-parent)|ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript)	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rigid:aYHI8FgpiJzW6QwvV4KrURs2Gco	false	crosslinked residues:493-493	crosslinked residues:188-188	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9ULR0	uniprotkb:Q15393	intact:EBI-2557660|uniprotkb:Q9BT05|uniprotkb:Q96IL2|ensembl:ENSP00000376973	intact:EBI-346977|uniprotkb:Q6NTI8|uniprotkb:Q96GC0|uniprotkb:Q9BPY2|uniprotkb:Q9UFX7|uniprotkb:Q9UJ29|ensembl:ENSP00000305790	psi-mi:isy1_human(display_long)|uniprotkb:ISY1(gene name)|psi-mi:ISY1(display_short)|uniprotkb:KIAA1160(gene name synonym)	psi-mi:sf3b3_human(display_long)|uniprotkb:SF3B3(gene name)|psi-mi:SF3B3(display_short)|uniprotkb:KIAA0017(gene name synonym)|uniprotkb:SAP130(gene name synonym)|uniprotkb:Spliceosome-associated protein 130(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 130 kDa subunit(gene name synonym)|uniprotkb:STAF130(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139701|imex:IM-24432-22|dip:DIP-199123E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186398.1|refseq:NP_001191819.1|refseq:NP_065752.1|dip:DIP-56636N|ensembl:ENSG00000240682(gene)|ensembl:ENST00000393295(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071020"(post-spliceosomal complex)|interpro:IPR009360(Isy1-like splicing)|interpro:IPR029012|interpro:IPR037200|mint:Q9ULR0|rcsb pdb:5YZG|rcsb pdb:6FF7|rcsb pdb:6ZYM|rcsb pdb:7A5P|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163	refseq:NP_036558.3|dip:DIP-28152N|ensembl:ENSG00000189091(gene)|ensembl:ENST00000302516(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|rcsb pdb:5O9Z|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|go:"GO:0005730"(nucleolus)|go:"GO:0008380"(RNA splicing)|rcsb pdb:5ZYA|rcsb pdb:6AH0|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR036322|mint:Q15393|rcsb pdb:5IFE	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:t4QKu0uotUIJIzR8DTXWje21U1A9606	rogid:gnCSXjZ/bwNXair6kyQUKoKIwbM9606	rigid:IHnqcCHvOx5CC+xORYVjRJBeM4o	false	crosslinked residues:112-112	crosslinked residues:296-296	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96NB3	uniprotkb:O60306	intact:EBI-3920997|ensembl:ENSP00000354518|uniprotkb:Q96F60|uniprotkb:Q96GZ5|uniprotkb:Q9BU38	intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3	psi-mi:zn830_human(display_long)|uniprotkb:ZNF830(gene name)|psi-mi:ZNF830(display_short)|uniprotkb:CCDC16(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 16(gene name synonym)	psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	De et al. (2015)	pubmed:25599396|doi:10.1038/nsmb.2951|imex:IM-24432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16139722|imex:IM-24432-23|dip:DIP-199115E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198783(gene)|ensembl:ENST00000361952(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001546"(preantral ovarian follicle growth)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060729"(intestinal epithelial structure maintenance)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR036236|interpro:IPR040050|mint:Q96NB3|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|refseq:NP_443089.3|dip:DIP-61544N	ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:4PbBUxZP6ipr8qKoU7JWlkldInE9606	rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606	rigid:6kKlAF8jCCPZHHLjUqjwQqSMFL0	false	crosslinked residues:339-339	crosslinked residues:201-201	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)