#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P31386 uniprotkb:Q3E840 intact:EBI-2046012|uniprotkb:D6VPJ8|ensemblfungi:YAL020C intact:EBI-2055307|uniprotkb:D6VPT1|ensemblfungi:YBL071W-A psi-mi:ats1_yeast(display_long)|uniprotkb:Alpha-tubulin suppressor 1(gene name synonym)|uniprotkb:ATS1(gene name)|psi-mi:ATS1(display_short)|uniprotkb:KTI13(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 13(gene name synonym)|uniprotkb:FUN28(orf name)|uniprotkb:YAL006(orf name)|uniprotkb:YAL020C(locus name) psi-mi:dph3_yeast(display_long)|uniprotkb:DPH3(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 11(gene name synonym)|uniprotkb:YBL071W-A(locus name)|uniprotkb:KTI11(gene name)|psi-mi:KTI11(display_short) psi-mi:"MI:0096"(pull down) Glatt et al. (2015) pubmed:25543256|doi:"https://doi.org/10.1016/j.str.2014.11.008"|imex:IM-24195 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16136397|imex:IM-24195-1|dip:DIP-137936E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009382.2|sgd:S000000018|dip:DIP-7890N|mint:P31386|ensemblfungi:YAL020C(gene)|ensemblfungi:YAL020C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4D4Q|rcsb pdb:4X33 refseq:NP_660100.1|sgd:S000007587|dip:DIP-52225N|mint:Q3E840|ensemblfungi:YBL071W-A(gene)|ensemblfungi:YBL071W-A_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016730"(oxidoreductase activity, acting on iron-sulfur proteins as donors)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR044248|rcsb pdb:1YOP|rcsb pdb:1YWS|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4X33|rcsb pdb:5AX2|reactome:R-SCE-5358493 psi-mi:"MI:0465"(dip) crc64:3C6F4BE180479096 crc64:8B27A307831B0ECE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:O36Rg2N1h1h4aVs0tSGc8xtbAxQ559292 rogid:GwQlZVh0IRJ/OMoCjHic//fuHZE559292 rigid:hKx5fYtjCoOJu5LjnfODEbNt1aI false - glutathione s tranferase tag:n-n|mutation disrupting interaction strength:4-4|mutation disrupting interaction strength:5-5|mutation decreasing interaction strength:8-8|necessary binding region:1-7 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P31386 uniprotkb:Q3E840 intact:EBI-2046012|uniprotkb:D6VPJ8|ensemblfungi:YAL020C intact:EBI-2055307|uniprotkb:D6VPT1|ensemblfungi:YBL071W-A psi-mi:ats1_yeast(display_long)|uniprotkb:Alpha-tubulin suppressor 1(gene name synonym)|uniprotkb:ATS1(gene name)|psi-mi:ATS1(display_short)|uniprotkb:KTI13(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 13(gene name synonym)|uniprotkb:FUN28(orf name)|uniprotkb:YAL006(orf name)|uniprotkb:YAL020C(locus name) psi-mi:dph3_yeast(display_long)|uniprotkb:DPH3(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 11(gene name synonym)|uniprotkb:YBL071W-A(locus name)|uniprotkb:KTI11(gene name)|psi-mi:KTI11(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Glatt et al. (2015) pubmed:25543256|doi:"https://doi.org/10.1016/j.str.2014.11.008"|imex:IM-24195 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16136460|imex:IM-24195-3|dip:DIP-137936E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009382.2|sgd:S000000018|dip:DIP-7890N|mint:P31386|ensemblfungi:YAL020C(gene)|ensemblfungi:YAL020C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4D4Q|rcsb pdb:4X33 refseq:NP_660100.1|sgd:S000007587|dip:DIP-52225N|mint:Q3E840|ensemblfungi:YBL071W-A(gene)|ensemblfungi:YBL071W-A_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016730"(oxidoreductase activity, acting on iron-sulfur proteins as donors)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR044248|rcsb pdb:1YOP|rcsb pdb:1YWS|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4X33|rcsb pdb:5AX2|reactome:R-SCE-5358493 psi-mi:"MI:0465"(dip) crc64:3C6F4BE180479096 crc64:8B27A307831B0ECE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:O36Rg2N1h1h4aVs0tSGc8xtbAxQ559292 rogid:GwQlZVh0IRJ/OMoCjHic//fuHZE559292 rigid:hKx5fYtjCoOJu5LjnfODEbNt1aI false mutation decreasing interaction strength:229-229|mutation increasing interaction strength:296-296|mutation increasing interaction strength:297-297 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40487 uniprotkb:Q3E840 intact:EBI-25162|uniprotkb:D6VVI4|ensemblfungi:YIL103W intact:EBI-2055307|uniprotkb:D6VPT1|ensemblfungi:YBL071W-A psi-mi:dph1_yeast(display_long)|uniprotkb:DPH1(gene name)|psi-mi:DPH1(display_short)|uniprotkb:Diphthamide biosynthesis protein 1(gene name synonym)|uniprotkb:Diphtheria toxin resistance protein 1(gene name synonym)|uniprotkb:"S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1"(gene name synonym)|uniprotkb:YIL103W(locus name) psi-mi:dph3_yeast(display_long)|uniprotkb:DPH3(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 11(gene name synonym)|uniprotkb:YBL071W-A(locus name)|uniprotkb:KTI11(gene name)|psi-mi:KTI11(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Glatt et al. (2015) pubmed:25543256|doi:"https://doi.org/10.1016/j.str.2014.11.008"|imex:IM-24195 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16136427|imex:IM-24195-2|dip:DIP-146294E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012163.1|sgd:S000001365|mint:P40487|dip:DIP-5653N|ensemblfungi:YIL103W(gene)|ensemblfungi:YIL103W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0090560"("2-(3-amino-3-carboxypropyl)histidine synthase activity")|interpro:IPR016435(Diphthamide synthesis, DHP1)|interpro:IPR035435|interpro:IPR042263|interpro:IPR042264|interpro:IPR042265|reactome:R-SCE-5358493 refseq:NP_660100.1|sgd:S000007587|dip:DIP-52225N|mint:Q3E840|ensemblfungi:YBL071W-A(gene)|ensemblfungi:YBL071W-A_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016730"(oxidoreductase activity, acting on iron-sulfur proteins as donors)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR044248|rcsb pdb:1YOP|rcsb pdb:1YWS|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4X33|rcsb pdb:5AX2|reactome:R-SCE-5358493 psi-mi:"MI:0465"(dip) crc64:22E93852E03C6722 crc64:8B27A307831B0ECE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:zk1Esuvz7u5GtymKbFzfv+PFAPQ559292 rogid:GwQlZVh0IRJ/OMoCjHic//fuHZE559292 rigid:DN4tF59YoovB8wy8kcLUNbXUJd4 false myc tag:c-c ha tag:n-n|mutation disrupting interaction strength:50-50|mutation disrupting interaction strength:25-25|mutation disrupting interaction strength:27-27|mutation disrupting interaction strength:47-47 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P31386 uniprotkb:Q3E840 intact:EBI-2046012|uniprotkb:D6VPJ8|ensemblfungi:YAL020C intact:EBI-2055307|uniprotkb:D6VPT1|ensemblfungi:YBL071W-A psi-mi:ats1_yeast(display_long)|uniprotkb:Alpha-tubulin suppressor 1(gene name synonym)|uniprotkb:ATS1(gene name)|psi-mi:ATS1(display_short)|uniprotkb:KTI13(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 13(gene name synonym)|uniprotkb:FUN28(orf name)|uniprotkb:YAL006(orf name)|uniprotkb:YAL020C(locus name) psi-mi:dph3_yeast(display_long)|uniprotkb:DPH3(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 11(gene name synonym)|uniprotkb:YBL071W-A(locus name)|uniprotkb:KTI11(gene name)|psi-mi:KTI11(display_short) psi-mi:"MI:0077"(nuclear magnetic resonance) Glatt et al. (2015) pubmed:25543256|doi:"https://doi.org/10.1016/j.str.2014.11.008"|imex:IM-24195 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16136486|imex:IM-24195-4|dip:DIP-137936E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009382.2|sgd:S000000018|dip:DIP-7890N|mint:P31386|ensemblfungi:YAL020C(gene)|ensemblfungi:YAL020C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4D4Q|rcsb pdb:4X33 refseq:NP_660100.1|sgd:S000007587|dip:DIP-52225N|mint:Q3E840|ensemblfungi:YBL071W-A(gene)|ensemblfungi:YBL071W-A_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016730"(oxidoreductase activity, acting on iron-sulfur proteins as donors)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR044248|rcsb pdb:1YOP|rcsb pdb:1YWS|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4X33|rcsb pdb:5AX2|reactome:R-SCE-5358493 psi-mi:"MI:0465"(dip) crc64:3C6F4BE180479096 crc64:8B27A307831B0ECE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:O36Rg2N1h1h4aVs0tSGc8xtbAxQ559292 rogid:GwQlZVh0IRJ/OMoCjHic//fuHZE559292 rigid:hKx5fYtjCoOJu5LjnfODEbNt1aI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3E840 uniprotkb:P31386 intact:EBI-2055307|uniprotkb:D6VPT1|ensemblfungi:YBL071W-A intact:EBI-2046012|uniprotkb:D6VPJ8|ensemblfungi:YAL020C psi-mi:dph3_yeast(display_long)|uniprotkb:DPH3(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 11(gene name synonym)|uniprotkb:YBL071W-A(locus name)|uniprotkb:KTI11(gene name)|psi-mi:KTI11(display_short) psi-mi:ats1_yeast(display_long)|uniprotkb:Alpha-tubulin suppressor 1(gene name synonym)|uniprotkb:ATS1(gene name)|psi-mi:ATS1(display_short)|uniprotkb:KTI13(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 13(gene name synonym)|uniprotkb:FUN28(orf name)|uniprotkb:YAL006(orf name)|uniprotkb:YAL020C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Glatt et al. (2015) pubmed:25543256|doi:"https://doi.org/10.1016/j.str.2014.11.008"|imex:IM-24195 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16136503|imex:IM-24195-5|dip:DIP-137936E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_660100.1|sgd:S000007587|dip:DIP-52225N|mint:Q3E840|ensemblfungi:YBL071W-A(gene)|ensemblfungi:YBL071W-A_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016730"(oxidoreductase activity, acting on iron-sulfur proteins as donors)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR044248|rcsb pdb:1YOP|rcsb pdb:1YWS|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4X33|rcsb pdb:5AX2|reactome:R-SCE-5358493 refseq:NP_009382.2|sgd:S000000018|dip:DIP-7890N|mint:P31386|ensemblfungi:YAL020C(gene)|ensemblfungi:YAL020C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4D4Q|rcsb pdb:4X33 psi-mi:"MI:0465"(dip) crc64:8B27A307831B0ECE crc64:3C6F4BE180479096 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:GwQlZVh0IRJ/OMoCjHic//fuHZE559292 rogid:O36Rg2N1h1h4aVs0tSGc8xtbAxQ559292 rigid:hKx5fYtjCoOJu5LjnfODEbNt1aI false mutation decreasing interaction strength:4-4|necessary binding region:1-7|mutation decreasing interaction strength:4-5|ha tag:n-n|mutation decreasing interaction strength:9-9,7-7 myc tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3E840 uniprotkb:P31386 intact:EBI-2055307|uniprotkb:D6VPT1|ensemblfungi:YBL071W-A intact:EBI-2046012|uniprotkb:D6VPJ8|ensemblfungi:YAL020C psi-mi:dph3_yeast(display_long)|uniprotkb:DPH3(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 11(gene name synonym)|uniprotkb:YBL071W-A(locus name)|uniprotkb:KTI11(gene name)|psi-mi:KTI11(display_short) psi-mi:ats1_yeast(display_long)|uniprotkb:Alpha-tubulin suppressor 1(gene name synonym)|uniprotkb:ATS1(gene name)|psi-mi:ATS1(display_short)|uniprotkb:KTI13(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 13(gene name synonym)|uniprotkb:FUN28(orf name)|uniprotkb:YAL006(orf name)|uniprotkb:YAL020C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Glatt et al. (2015) pubmed:25543256|doi:"https://doi.org/10.1016/j.str.2014.11.008"|imex:IM-24195 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16136535|imex:IM-24195-6|dip:DIP-137936E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_660100.1|sgd:S000007587|dip:DIP-52225N|mint:Q3E840|ensemblfungi:YBL071W-A(gene)|ensemblfungi:YBL071W-A_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016730"(oxidoreductase activity, acting on iron-sulfur proteins as donors)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR044248|rcsb pdb:1YOP|rcsb pdb:1YWS|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4X33|rcsb pdb:5AX2|reactome:R-SCE-5358493 refseq:NP_009382.2|sgd:S000000018|dip:DIP-7890N|mint:P31386|ensemblfungi:YAL020C(gene)|ensemblfungi:YAL020C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4D4Q|rcsb pdb:4X33 psi-mi:"MI:0465"(dip) crc64:8B27A307831B0ECE crc64:3C6F4BE180479096 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:GwQlZVh0IRJ/OMoCjHic//fuHZE559292 rogid:O36Rg2N1h1h4aVs0tSGc8xtbAxQ559292 rigid:hKx5fYtjCoOJu5LjnfODEbNt1aI false myc tag:c-c ha tag:n-n|mutation decreasing interaction strength:229-229 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31386 uniprotkb:Q3E840 intact:EBI-2046012|uniprotkb:D6VPJ8|ensemblfungi:YAL020C intact:EBI-2055307|uniprotkb:D6VPT1|ensemblfungi:YBL071W-A psi-mi:ats1_yeast(display_long)|uniprotkb:Alpha-tubulin suppressor 1(gene name synonym)|uniprotkb:ATS1(gene name)|psi-mi:ATS1(display_short)|uniprotkb:KTI13(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 13(gene name synonym)|uniprotkb:FUN28(orf name)|uniprotkb:YAL006(orf name)|uniprotkb:YAL020C(locus name) psi-mi:dph3_yeast(display_long)|uniprotkb:DPH3(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 11(gene name synonym)|uniprotkb:YBL071W-A(locus name)|uniprotkb:KTI11(gene name)|psi-mi:KTI11(display_short) psi-mi:"MI:0096"(pull down) Glatt et al. (2015) pubmed:25543256|doi:"https://doi.org/10.1016/j.str.2014.11.008"|imex:IM-24195 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16136608|imex:IM-24195-9|dip:DIP-137936E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009382.2|sgd:S000000018|dip:DIP-7890N|mint:P31386|ensemblfungi:YAL020C(gene)|ensemblfungi:YAL020C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4D4Q|rcsb pdb:4X33 refseq:NP_660100.1|sgd:S000007587|dip:DIP-52225N|mint:Q3E840|ensemblfungi:YBL071W-A(gene)|ensemblfungi:YBL071W-A_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016730"(oxidoreductase activity, acting on iron-sulfur proteins as donors)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR044248|rcsb pdb:1YOP|rcsb pdb:1YWS|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4X33|rcsb pdb:5AX2|reactome:R-SCE-5358493 psi-mi:"MI:0465"(dip) crc64:3C6F4BE180479096 crc64:8B27A307831B0ECE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:O36Rg2N1h1h4aVs0tSGc8xtbAxQ559292 rogid:GwQlZVh0IRJ/OMoCjHic//fuHZE559292 rigid:hKx5fYtjCoOJu5LjnfODEbNt1aI false mutation disrupting interaction strength:229-229|mutation disrupting interaction strength:229-229|mutation decreasing interaction strength:294-294 glutathione s tranferase tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P31386 uniprotkb:Q3E840 intact:EBI-2046012|uniprotkb:D6VPJ8|ensemblfungi:YAL020C intact:EBI-2055307|uniprotkb:D6VPT1|ensemblfungi:YBL071W-A psi-mi:ats1_yeast(display_long)|uniprotkb:Alpha-tubulin suppressor 1(gene name synonym)|uniprotkb:ATS1(gene name)|psi-mi:ATS1(display_short)|uniprotkb:KTI13(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 13(gene name synonym)|uniprotkb:FUN28(orf name)|uniprotkb:YAL006(orf name)|uniprotkb:YAL020C(locus name) psi-mi:dph3_yeast(display_long)|uniprotkb:DPH3(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 11(gene name synonym)|uniprotkb:YBL071W-A(locus name)|uniprotkb:KTI11(gene name)|psi-mi:KTI11(display_short) psi-mi:"MI:0028"(cosedimentation in solution) Glatt et al. (2015) pubmed:25543256|doi:"https://doi.org/10.1016/j.str.2014.11.008"|imex:IM-24195 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16136591|imex:IM-24195-8|dip:DIP-137936E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009382.2|sgd:S000000018|dip:DIP-7890N|mint:P31386|ensemblfungi:YAL020C(gene)|ensemblfungi:YAL020C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4D4Q|rcsb pdb:4X33 refseq:NP_660100.1|sgd:S000007587|dip:DIP-52225N|mint:Q3E840|ensemblfungi:YBL071W-A(gene)|ensemblfungi:YBL071W-A_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016730"(oxidoreductase activity, acting on iron-sulfur proteins as donors)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR044248|rcsb pdb:1YOP|rcsb pdb:1YWS|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4X33|rcsb pdb:5AX2|reactome:R-SCE-5358493 psi-mi:"MI:0465"(dip) crc64:3C6F4BE180479096 crc64:8B27A307831B0ECE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:O36Rg2N1h1h4aVs0tSGc8xtbAxQ559292 rogid:GwQlZVh0IRJ/OMoCjHic//fuHZE559292 rigid:hKx5fYtjCoOJu5LjnfODEbNt1aI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31386 uniprotkb:Q3E840 intact:EBI-2046012|uniprotkb:D6VPJ8|ensemblfungi:YAL020C intact:EBI-2055307|uniprotkb:D6VPT1|ensemblfungi:YBL071W-A psi-mi:ats1_yeast(display_long)|uniprotkb:Alpha-tubulin suppressor 1(gene name synonym)|uniprotkb:ATS1(gene name)|psi-mi:ATS1(display_short)|uniprotkb:KTI13(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 13(gene name synonym)|uniprotkb:FUN28(orf name)|uniprotkb:YAL006(orf name)|uniprotkb:YAL020C(locus name) psi-mi:dph3_yeast(display_long)|uniprotkb:DPH3(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 11(gene name synonym)|uniprotkb:YBL071W-A(locus name)|uniprotkb:KTI11(gene name)|psi-mi:KTI11(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Glatt et al. (2015) pubmed:25543256|doi:"https://doi.org/10.1016/j.str.2014.11.008"|imex:IM-24195 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16136559|imex:IM-24195-7|dip:DIP-137936E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009382.2|sgd:S000000018|dip:DIP-7890N|mint:P31386|ensemblfungi:YAL020C(gene)|ensemblfungi:YAL020C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4D4Q|rcsb pdb:4X33 refseq:NP_660100.1|sgd:S000007587|dip:DIP-52225N|mint:Q3E840|ensemblfungi:YBL071W-A(gene)|ensemblfungi:YBL071W-A_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016730"(oxidoreductase activity, acting on iron-sulfur proteins as donors)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR044248|rcsb pdb:1YOP|rcsb pdb:1YWS|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4X33|rcsb pdb:5AX2|reactome:R-SCE-5358493 psi-mi:"MI:0465"(dip) crc64:3C6F4BE180479096 crc64:8B27A307831B0ECE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:O36Rg2N1h1h4aVs0tSGc8xtbAxQ559292 rogid:GwQlZVh0IRJ/OMoCjHic//fuHZE559292 rigid:hKx5fYtjCoOJu5LjnfODEbNt1aI false - mutation decreasing interaction strength:4-4|mutation decreasing interaction strength:5-5|mutation decreasing interaction strength:4-5|mutation decreasing interaction strength:8-8|mutation decreasing interaction strength:8-8,6-6 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02908 uniprotkb:Q3E840 intact:EBI-33957|uniprotkb:D6W3T1|ensemblfungi:YPL086C intact:EBI-2055307|uniprotkb:D6VPT1|ensemblfungi:YBL071W-A psi-mi:elp3_yeast(display_long)|uniprotkb:ELP3(gene name)|psi-mi:ELP3(display_short)|uniprotkb:Gamma-toxin target 3(gene name synonym)|uniprotkb:HPA1(gene name synonym)|uniprotkb:TOT3(gene name synonym)|uniprotkb:"tRNA uridine(34) acetyltransferase"(gene name synonym)|uniprotkb:YPL086C(locus name) psi-mi:dph3_yeast(display_long)|uniprotkb:DPH3(gene name synonym)|uniprotkb:Kluyveromyces lactis toxin-insensitive protein 11(gene name synonym)|uniprotkb:YBL071W-A(locus name)|uniprotkb:KTI11(gene name)|psi-mi:KTI11(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Glatt et al. (2015) pubmed:25543256|doi:"https://doi.org/10.1016/j.str.2014.11.008"|imex:IM-24195 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16136636|imex:IM-24195-10|dip:DIP-130848E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015239.1|sgd:S000006007|mint:Q02908|dip:DIP-2385N|ensemblfungi:YPL086C(gene)|ensemblfungi:YPL086C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002926"(tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0106261"("tRNA uridine(34) acetyltransferase activity")|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032432|interpro:IPR034687|interpro:IPR039661|rcsb pdb:6QK7 refseq:NP_660100.1|sgd:S000007587|dip:DIP-52225N|mint:Q3E840|ensemblfungi:YBL071W-A(gene)|ensemblfungi:YBL071W-A_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016730"(oxidoreductase activity, acting on iron-sulfur proteins as donors)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR044248|rcsb pdb:1YOP|rcsb pdb:1YWS|rcsb pdb:4D4O|rcsb pdb:4D4P|rcsb pdb:4X33|rcsb pdb:5AX2|reactome:R-SCE-5358493 psi-mi:"MI:0465"(dip) crc64:64EF8B42D3C3102E crc64:8B27A307831B0ECE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:otpUoDpD0rKMsXypvcWE4zc0uxI559292 rogid:GwQlZVh0IRJ/OMoCjHic//fuHZE559292 rigid:R1qdnLRK5awlPPXzuz4ne0f3Dg4 false myc tag:c-c ha tag:n-n|mutation disrupting interaction strength:50-50 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)