#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O75582 uniprotkb:Q9Y4C1 intact:EBI-73869|uniprotkb:O95316|uniprotkb:Q96AF7|uniprotkb:B7Z2Y5|intact:EBI-14183507|intact:EBI-12850788|ensembl:ENSP00000479667 intact:EBI-2515339|ensembl:ENSP00000323659|ensembl:ENSP00000386516|ensembl:ENSP00000386660|uniprotkb:Q68UT9|uniprotkb:Q8IY08|uniprotkb:Q68D47|uniprotkb:Q53S72|uniprotkb:Q6N050|uniprotkb:D6W5M3 psi-mi:ks6a5_human(display_long)|uniprotkb:Nuclear mitogen- and stress-activated protein kinase 1(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 5(gene name synonym)|uniprotkb:RSK-like protein kinase(gene name synonym)|uniprotkb:RPS6KA5(gene name)|psi-mi:RPS6KA5(display_short)|uniprotkb:MSK1(gene name synonym) psi-mi:kdm3a_human(display_long)|uniprotkb:KDM3A(gene name)|psi-mi:KDM3A(display_short)|uniprotkb:JHDM2A(gene name synonym)|uniprotkb:JMJD1(gene name synonym)|uniprotkb:JMJD1A(gene name synonym)|uniprotkb:KIAA0742(gene name synonym)|uniprotkb:TSGA(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2A(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1A(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3A"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cheng et al. (2014) pubmed:25535969|doi:10.1371/journal.pbio.1002026|imex:IM-24092 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16135956|imex:IM-24092-1|dip:DIP-198518E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004746.2|refseq:NP_872198.1|refseq:NP_001309164.1|refseq:NP_001309166.1|dip:DIP-30894N|ensembl:ENSG00000100784(gene)|ensembl:ENST00000614987(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043987"(histone H3-S10 phosphorylation)|go:"GO:0043988"(histone H3-S28 phosphorylation)|go:"GO:0043990"(histone H2A-S1 phosphorylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:O75582|rcsb pdb:1VZO|rcsb pdb:3KN5|rcsb pdb:3KN6|reactome:R-HSA-198753|reactome:R-HSA-199920|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-5621575 ensembl:ENSG00000115548(gene)|ensembl:ENST00000312912(transcript)|ensembl:ENST00000409064(transcript)|ensembl:ENST00000409556(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0000785"(chromatin)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046293"(formaldehyde biosynthetic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9Y4C1|reactome:R-HSA-3214842|reactome:R-HSA-9029569|refseq:NP_001140160.1|refseq:NP_060903.2|refseq:XP_016859982.1|dip:DIP-53661N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:8W2PRa/aVTLxiBJEbbXoebPqlco9606 rogid:XF6xqiiGohV0b2e/bzVx+J0XH7I9606 rigid:pCKbjm/grF23d11OljJV/pX/pYY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P42224-1 uniprotkb:Q9Y4C1 intact:EBI-15711971|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 intact:EBI-2515339|ensembl:ENSP00000323659|ensembl:ENSP00000386516|ensembl:ENSP00000386660|uniprotkb:Q68UT9|uniprotkb:Q8IY08|uniprotkb:Q68D47|uniprotkb:Q53S72|uniprotkb:Q6N050|uniprotkb:D6W5M3 psi-mi:p42224-1(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym)|uniprotkb:p91(isoform synonym) psi-mi:kdm3a_human(display_long)|uniprotkb:KDM3A(gene name)|psi-mi:KDM3A(display_short)|uniprotkb:JHDM2A(gene name synonym)|uniprotkb:JMJD1(gene name synonym)|uniprotkb:JMJD1A(gene name synonym)|uniprotkb:KIAA0742(gene name synonym)|uniprotkb:TSGA(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2A(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1A(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3A"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cheng et al. (2014) pubmed:25535969|doi:10.1371/journal.pbio.1002026|imex:IM-24092 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16136003|imex:IM-24092-3|dip:DIP-198519E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|intact:EBI-1057697(isoform-parent) ensembl:ENSG00000115548(gene)|ensembl:ENST00000312912(transcript)|ensembl:ENST00000409064(transcript)|ensembl:ENST00000409556(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0000785"(chromatin)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046293"(formaldehyde biosynthetic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9Y4C1|reactome:R-HSA-3214842|reactome:R-HSA-9029569|refseq:NP_001140160.1|refseq:NP_060903.2|refseq:XP_016859982.1|dip:DIP-53661N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 rogid:XF6xqiiGohV0b2e/bzVx+J0XH7I9606 rigid:5dfw1d5Q+yUsXkdXBpHXnzpERyA false - flag tag:n-n|mutation disrupting interaction strength:264-264 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O75582 uniprotkb:Q9Y4C1 intact:EBI-73869|uniprotkb:O95316|uniprotkb:Q96AF7|uniprotkb:B7Z2Y5|intact:EBI-14183507|intact:EBI-12850788|ensembl:ENSP00000479667 intact:EBI-2515339|ensembl:ENSP00000323659|ensembl:ENSP00000386516|ensembl:ENSP00000386660|uniprotkb:Q68UT9|uniprotkb:Q8IY08|uniprotkb:Q68D47|uniprotkb:Q53S72|uniprotkb:Q6N050|uniprotkb:D6W5M3 psi-mi:ks6a5_human(display_long)|uniprotkb:Nuclear mitogen- and stress-activated protein kinase 1(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 5(gene name synonym)|uniprotkb:RSK-like protein kinase(gene name synonym)|uniprotkb:RPS6KA5(gene name)|psi-mi:RPS6KA5(display_short)|uniprotkb:MSK1(gene name synonym) psi-mi:kdm3a_human(display_long)|uniprotkb:KDM3A(gene name)|psi-mi:KDM3A(display_short)|uniprotkb:JHDM2A(gene name synonym)|uniprotkb:JMJD1(gene name synonym)|uniprotkb:JMJD1A(gene name synonym)|uniprotkb:KIAA0742(gene name synonym)|uniprotkb:TSGA(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2A(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1A(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3A"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cheng et al. (2014) pubmed:25535969|doi:10.1371/journal.pbio.1002026|imex:IM-24092 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16136025|imex:IM-24092-4|dip:DIP-198518E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004746.2|refseq:NP_872198.1|refseq:NP_001309164.1|refseq:NP_001309166.1|dip:DIP-30894N|ensembl:ENSG00000100784(gene)|ensembl:ENST00000614987(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043987"(histone H3-S10 phosphorylation)|go:"GO:0043988"(histone H3-S28 phosphorylation)|go:"GO:0043990"(histone H2A-S1 phosphorylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:O75582|rcsb pdb:1VZO|rcsb pdb:3KN5|rcsb pdb:3KN6|reactome:R-HSA-198753|reactome:R-HSA-199920|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-5621575 ensembl:ENSG00000115548(gene)|ensembl:ENST00000312912(transcript)|ensembl:ENST00000409064(transcript)|ensembl:ENST00000409556(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0000785"(chromatin)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046293"(formaldehyde biosynthetic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9Y4C1|reactome:R-HSA-3214842|reactome:R-HSA-9029569|refseq:NP_001140160.1|refseq:NP_060903.2|refseq:XP_016859982.1|dip:DIP-53661N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:8W2PRa/aVTLxiBJEbbXoebPqlco9606 rogid:XF6xqiiGohV0b2e/bzVx+J0XH7I9606 rigid:pCKbjm/grF23d11OljJV/pX/pYY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y4C1 uniprotkb:O75582-1 intact:EBI-2515339|ensembl:ENSP00000323659|ensembl:ENSP00000386516|ensembl:ENSP00000386660|uniprotkb:Q68UT9|uniprotkb:Q8IY08|uniprotkb:Q68D47|uniprotkb:Q53S72|uniprotkb:Q6N050|uniprotkb:D6W5M3 intact:EBI-16135973|ensembl:ENSP00000479667 psi-mi:kdm3a_human(display_long)|uniprotkb:KDM3A(gene name)|psi-mi:KDM3A(display_short)|uniprotkb:JHDM2A(gene name synonym)|uniprotkb:JMJD1(gene name synonym)|uniprotkb:JMJD1A(gene name synonym)|uniprotkb:KIAA0742(gene name synonym)|uniprotkb:TSGA(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2A(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1A(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3A"(gene name synonym) psi-mi:o75582-1(display_long)|uniprotkb:RPS6KA5(gene name)|psi-mi:RPS6KA5(display_short)|uniprotkb:MSK1(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 5(gene name synonym)|uniprotkb:Nuclear mitogen- and stress-activated protein kinase 1(gene name synonym)|uniprotkb:RSK-like protein kinase(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Cheng et al. (2014) pubmed:25535969|doi:10.1371/journal.pbio.1002026|imex:IM-24092 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-16136043|imex:IM-24092-5|dip:DIP-198518E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115548(gene)|ensembl:ENST00000312912(transcript)|ensembl:ENST00000409064(transcript)|ensembl:ENST00000409556(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0000785"(chromatin)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046293"(formaldehyde biosynthetic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9Y4C1|reactome:R-HSA-3214842|reactome:R-HSA-9029569|refseq:NP_001140160.1|refseq:NP_060903.2|refseq:XP_016859982.1|dip:DIP-53661N intact:EBI-73869(isoform-parent)|ensembl:ENSG00000100784(gene)|ensembl:ENST00000614987(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:XF6xqiiGohV0b2e/bzVx+J0XH7I9606 rogid:8W2PRa/aVTLxiBJEbbXoebPqlco9606 rigid:pCKbjm/grF23d11OljJV/pX/pYY false sufficient binding region:1-394|mutation disrupting interaction rate:264-264|O-phospho-L-serine:264-264 - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:O75582-1 uniprotkb:Q9Y4C1 intact:EBI-16135973|ensembl:ENSP00000479667 intact:EBI-2515339|ensembl:ENSP00000323659|ensembl:ENSP00000386516|ensembl:ENSP00000386660|uniprotkb:Q68UT9|uniprotkb:Q8IY08|uniprotkb:Q68D47|uniprotkb:Q53S72|uniprotkb:Q6N050|uniprotkb:D6W5M3 psi-mi:o75582-1(display_long)|uniprotkb:RPS6KA5(gene name)|psi-mi:RPS6KA5(display_short)|uniprotkb:MSK1(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 5(gene name synonym)|uniprotkb:Nuclear mitogen- and stress-activated protein kinase 1(gene name synonym)|uniprotkb:RSK-like protein kinase(gene name synonym) psi-mi:kdm3a_human(display_long)|uniprotkb:KDM3A(gene name)|psi-mi:KDM3A(display_short)|uniprotkb:JHDM2A(gene name synonym)|uniprotkb:JMJD1(gene name synonym)|uniprotkb:JMJD1A(gene name synonym)|uniprotkb:KIAA0742(gene name synonym)|uniprotkb:TSGA(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2A(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1A(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3A"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cheng et al. (2014) pubmed:25535969|doi:10.1371/journal.pbio.1002026|imex:IM-24092 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16135982|imex:IM-24092-2|dip:DIP-198518E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-73869(isoform-parent)|ensembl:ENSG00000100784(gene)|ensembl:ENST00000614987(transcript) ensembl:ENSG00000115548(gene)|ensembl:ENST00000312912(transcript)|ensembl:ENST00000409064(transcript)|ensembl:ENST00000409556(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0000785"(chromatin)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046293"(formaldehyde biosynthetic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9Y4C1|reactome:R-HSA-3214842|reactome:R-HSA-9029569|refseq:NP_001140160.1|refseq:NP_060903.2|refseq:XP_016859982.1|dip:DIP-53661N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:8W2PRa/aVTLxiBJEbbXoebPqlco9606 rogid:XF6xqiiGohV0b2e/bzVx+J0XH7I9606 rigid:pCKbjm/grF23d11OljJV/pX/pYY false flag tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y4C1 uniprotkb:P42224-1 intact:EBI-2515339|ensembl:ENSP00000323659|ensembl:ENSP00000386516|ensembl:ENSP00000386660|uniprotkb:Q68UT9|uniprotkb:Q8IY08|uniprotkb:Q68D47|uniprotkb:Q53S72|uniprotkb:Q6N050|uniprotkb:D6W5M3 intact:EBI-15711971|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 psi-mi:kdm3a_human(display_long)|uniprotkb:KDM3A(gene name)|psi-mi:KDM3A(display_short)|uniprotkb:JHDM2A(gene name synonym)|uniprotkb:JMJD1(gene name synonym)|uniprotkb:JMJD1A(gene name synonym)|uniprotkb:KIAA0742(gene name synonym)|uniprotkb:TSGA(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2A(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1A(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3A"(gene name synonym) psi-mi:p42224-1(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym)|uniprotkb:p91(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cheng et al. (2014) pubmed:25535969|doi:10.1371/journal.pbio.1002026|imex:IM-24092 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16136067|imex:IM-24092-6|dip:DIP-198519E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115548(gene)|ensembl:ENST00000312912(transcript)|ensembl:ENST00000409064(transcript)|ensembl:ENST00000409556(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0000785"(chromatin)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046293"(formaldehyde biosynthetic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9Y4C1|reactome:R-HSA-3214842|reactome:R-HSA-9029569|refseq:NP_001140160.1|refseq:NP_060903.2|refseq:XP_016859982.1|dip:DIP-53661N ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|intact:EBI-1057697(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:XF6xqiiGohV0b2e/bzVx+J0XH7I9606 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 rigid:5dfw1d5Q+yUsXkdXBpHXnzpERyA false flag tag:n-n ha tag:n-n|sufficient binding region:129-317 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y4C1 uniprotkb:P42224-1 intact:EBI-2515339|ensembl:ENSP00000323659|ensembl:ENSP00000386516|ensembl:ENSP00000386660|uniprotkb:Q68UT9|uniprotkb:Q8IY08|uniprotkb:Q68D47|uniprotkb:Q53S72|uniprotkb:Q6N050|uniprotkb:D6W5M3 intact:EBI-15711971|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 psi-mi:kdm3a_human(display_long)|uniprotkb:KDM3A(gene name)|psi-mi:KDM3A(display_short)|uniprotkb:JHDM2A(gene name synonym)|uniprotkb:JMJD1(gene name synonym)|uniprotkb:JMJD1A(gene name synonym)|uniprotkb:KIAA0742(gene name synonym)|uniprotkb:TSGA(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2A(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1A(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3A"(gene name synonym) psi-mi:p42224-1(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym)|uniprotkb:p91(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cheng et al. (2014) pubmed:25535969|doi:10.1371/journal.pbio.1002026|imex:IM-24092 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16136090|imex:IM-24092-7|dip:DIP-198519E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115548(gene)|ensembl:ENST00000312912(transcript)|ensembl:ENST00000409064(transcript)|ensembl:ENST00000409556(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0000785"(chromatin)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046293"(formaldehyde biosynthetic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9Y4C1|reactome:R-HSA-3214842|reactome:R-HSA-9029569|refseq:NP_001140160.1|refseq:NP_060903.2|refseq:XP_016859982.1|dip:DIP-53661N ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|intact:EBI-1057697(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:XF6xqiiGohV0b2e/bzVx+J0XH7I9606 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 rigid:5dfw1d5Q+yUsXkdXBpHXnzpERyA false flag tag:n-n|sufficient binding region:214-306 ha tag:n-n|sufficient binding region:231-317 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P42224-1 uniprotkb:Q9Y4C1 intact:EBI-15711971|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 intact:EBI-2515339|ensembl:ENSP00000323659|ensembl:ENSP00000386516|ensembl:ENSP00000386660|uniprotkb:Q68UT9|uniprotkb:Q8IY08|uniprotkb:Q68D47|uniprotkb:Q53S72|uniprotkb:Q6N050|uniprotkb:D6W5M3 psi-mi:p42224-1(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym)|uniprotkb:p91(isoform synonym) psi-mi:kdm3a_human(display_long)|uniprotkb:KDM3A(gene name)|psi-mi:KDM3A(display_short)|uniprotkb:JHDM2A(gene name synonym)|uniprotkb:JMJD1(gene name synonym)|uniprotkb:JMJD1A(gene name synonym)|uniprotkb:KIAA0742(gene name synonym)|uniprotkb:TSGA(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2A(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1A(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3A"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cheng et al. (2014) pubmed:25535969|doi:10.1371/journal.pbio.1002026|imex:IM-24092 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16136115|imex:IM-24092-8|dip:DIP-198519E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|intact:EBI-1057697(isoform-parent) ensembl:ENSG00000115548(gene)|ensembl:ENST00000312912(transcript)|ensembl:ENST00000409064(transcript)|ensembl:ENST00000409556(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0000785"(chromatin)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046293"(formaldehyde biosynthetic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9Y4C1|reactome:R-HSA-3214842|reactome:R-HSA-9029569|refseq:NP_001140160.1|refseq:NP_060903.2|refseq:XP_016859982.1|dip:DIP-53661N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 rogid:XF6xqiiGohV0b2e/bzVx+J0XH7I9606 rigid:5dfw1d5Q+yUsXkdXBpHXnzpERyA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P42224-1 uniprotkb:Q9Y4C1 intact:EBI-15711971|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 intact:EBI-2515339|ensembl:ENSP00000323659|ensembl:ENSP00000386516|ensembl:ENSP00000386660|uniprotkb:Q68UT9|uniprotkb:Q8IY08|uniprotkb:Q68D47|uniprotkb:Q53S72|uniprotkb:Q6N050|uniprotkb:D6W5M3 psi-mi:p42224-1(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym)|uniprotkb:p91(isoform synonym) psi-mi:kdm3a_human(display_long)|uniprotkb:KDM3A(gene name)|psi-mi:KDM3A(display_short)|uniprotkb:JHDM2A(gene name synonym)|uniprotkb:JMJD1(gene name synonym)|uniprotkb:JMJD1A(gene name synonym)|uniprotkb:KIAA0742(gene name synonym)|uniprotkb:TSGA(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2A(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1A(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3A"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cheng et al. (2014) pubmed:25535969|doi:10.1371/journal.pbio.1002026|imex:IM-24092 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16136132|imex:IM-24092-9|dip:DIP-198519E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|intact:EBI-1057697(isoform-parent) ensembl:ENSG00000115548(gene)|ensembl:ENST00000312912(transcript)|ensembl:ENST00000409064(transcript)|ensembl:ENST00000409556(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0000785"(chromatin)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046293"(formaldehyde biosynthetic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9Y4C1|reactome:R-HSA-3214842|reactome:R-HSA-9029569|refseq:NP_001140160.1|refseq:NP_060903.2|refseq:XP_016859982.1|dip:DIP-53661N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 rogid:XF6xqiiGohV0b2e/bzVx+J0XH7I9606 rigid:5dfw1d5Q+yUsXkdXBpHXnzpERyA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y4C1 uniprotkb:P42224-1 intact:EBI-2515339|ensembl:ENSP00000323659|ensembl:ENSP00000386516|ensembl:ENSP00000386660|uniprotkb:Q68UT9|uniprotkb:Q8IY08|uniprotkb:Q68D47|uniprotkb:Q53S72|uniprotkb:Q6N050|uniprotkb:D6W5M3 intact:EBI-15711971|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 psi-mi:kdm3a_human(display_long)|uniprotkb:KDM3A(gene name)|psi-mi:KDM3A(display_short)|uniprotkb:JHDM2A(gene name synonym)|uniprotkb:JMJD1(gene name synonym)|uniprotkb:JMJD1A(gene name synonym)|uniprotkb:KIAA0742(gene name synonym)|uniprotkb:TSGA(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2A(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1A(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3A"(gene name synonym) psi-mi:p42224-1(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym)|uniprotkb:p91(isoform synonym) psi-mi:"MI:0096"(pull down) Cheng et al. (2014) pubmed:25535969|doi:10.1371/journal.pbio.1002026|imex:IM-24092 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16136149|imex:IM-24092-10|dip:DIP-198519E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115548(gene)|ensembl:ENST00000312912(transcript)|ensembl:ENST00000409064(transcript)|ensembl:ENST00000409556(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0000785"(chromatin)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046293"(formaldehyde biosynthetic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9Y4C1|reactome:R-HSA-3214842|reactome:R-HSA-9029569|refseq:NP_001140160.1|refseq:NP_060903.2|refseq:XP_016859982.1|dip:DIP-53661N ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|intact:EBI-1057697(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:XF6xqiiGohV0b2e/bzVx+J0XH7I9606 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 rigid:5dfw1d5Q+yUsXkdXBpHXnzpERyA false sufficient binding region:1-394|glutathione s tranferase tag:n-n|mutation disrupting interaction strength:264-264 ha tag:n-n|sufficient binding region:129-317 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y4C1 uniprotkb:O75582-1 intact:EBI-2515339|ensembl:ENSP00000323659|ensembl:ENSP00000386516|ensembl:ENSP00000386660|uniprotkb:Q68UT9|uniprotkb:Q8IY08|uniprotkb:Q68D47|uniprotkb:Q53S72|uniprotkb:Q6N050|uniprotkb:D6W5M3 intact:EBI-16135973|ensembl:ENSP00000479667 psi-mi:kdm3a_human(display_long)|uniprotkb:KDM3A(gene name)|psi-mi:KDM3A(display_short)|uniprotkb:JHDM2A(gene name synonym)|uniprotkb:JMJD1(gene name synonym)|uniprotkb:JMJD1A(gene name synonym)|uniprotkb:KIAA0742(gene name synonym)|uniprotkb:TSGA(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2A(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1A(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3A"(gene name synonym) psi-mi:o75582-1(display_long)|uniprotkb:RPS6KA5(gene name)|psi-mi:RPS6KA5(display_short)|uniprotkb:MSK1(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 5(gene name synonym)|uniprotkb:Nuclear mitogen- and stress-activated protein kinase 1(gene name synonym)|uniprotkb:RSK-like protein kinase(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Cheng et al. (2014) pubmed:25535969|doi:10.1371/journal.pbio.1002026|imex:IM-24092 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-16136177|imex:IM-24092-11|dip:DIP-198518E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115548(gene)|ensembl:ENST00000312912(transcript)|ensembl:ENST00000409064(transcript)|ensembl:ENST00000409556(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0000785"(chromatin)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046293"(formaldehyde biosynthetic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9Y4C1|reactome:R-HSA-3214842|reactome:R-HSA-9029569|refseq:NP_001140160.1|refseq:NP_060903.2|refseq:XP_016859982.1|dip:DIP-53661N intact:EBI-73869(isoform-parent)|ensembl:ENSG00000100784(gene)|ensembl:ENST00000614987(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:XF6xqiiGohV0b2e/bzVx+J0XH7I9606 rogid:8W2PRa/aVTLxiBJEbbXoebPqlco9606 rigid:pCKbjm/grF23d11OljJV/pX/pYY false sufficient binding region:260-269|O-phospho-L-serine:264-264 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y4C1 uniprotkb:P42224-1 intact:EBI-2515339|ensembl:ENSP00000323659|ensembl:ENSP00000386516|ensembl:ENSP00000386660|uniprotkb:Q68UT9|uniprotkb:Q8IY08|uniprotkb:Q68D47|uniprotkb:Q53S72|uniprotkb:Q6N050|uniprotkb:D6W5M3 intact:EBI-15711971|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 psi-mi:kdm3a_human(display_long)|uniprotkb:KDM3A(gene name)|psi-mi:KDM3A(display_short)|uniprotkb:JHDM2A(gene name synonym)|uniprotkb:JMJD1(gene name synonym)|uniprotkb:JMJD1A(gene name synonym)|uniprotkb:KIAA0742(gene name synonym)|uniprotkb:TSGA(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2A(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1A(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3A"(gene name synonym) psi-mi:p42224-1(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym)|uniprotkb:p91(isoform synonym) psi-mi:"MI:0096"(pull down) Cheng et al. (2014) pubmed:25535969|doi:10.1371/journal.pbio.1002026|imex:IM-24092 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16136198|imex:IM-24092-12|dip:DIP-198519E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115548(gene)|ensembl:ENST00000312912(transcript)|ensembl:ENST00000409064(transcript)|ensembl:ENST00000409556(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0000785"(chromatin)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046293"(formaldehyde biosynthetic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9Y4C1|reactome:R-HSA-3214842|reactome:R-HSA-9029569|refseq:NP_001140160.1|refseq:NP_060903.2|refseq:XP_016859982.1|dip:DIP-53661N ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|intact:EBI-1057697(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:XF6xqiiGohV0b2e/bzVx+J0XH7I9606 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 rigid:5dfw1d5Q+yUsXkdXBpHXnzpERyA false sufficient binding region:1-394|his tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y4C1 uniprotkb:P42224-1 intact:EBI-2515339|ensembl:ENSP00000323659|ensembl:ENSP00000386516|ensembl:ENSP00000386660|uniprotkb:Q68UT9|uniprotkb:Q8IY08|uniprotkb:Q68D47|uniprotkb:Q53S72|uniprotkb:Q6N050|uniprotkb:D6W5M3 intact:EBI-15711971|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 psi-mi:kdm3a_human(display_long)|uniprotkb:KDM3A(gene name)|psi-mi:KDM3A(display_short)|uniprotkb:JHDM2A(gene name synonym)|uniprotkb:JMJD1(gene name synonym)|uniprotkb:JMJD1A(gene name synonym)|uniprotkb:KIAA0742(gene name synonym)|uniprotkb:TSGA(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2A(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1A(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3A"(gene name synonym) psi-mi:p42224-1(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym)|uniprotkb:p91(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cheng et al. (2014) pubmed:25535969|doi:10.1371/journal.pbio.1002026|imex:IM-24092 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16136221|imex:IM-24092-13|dip:DIP-198519E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115548(gene)|ensembl:ENST00000312912(transcript)|ensembl:ENST00000409064(transcript)|ensembl:ENST00000409556(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0000785"(chromatin)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046293"(formaldehyde biosynthetic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9Y4C1|reactome:R-HSA-3214842|reactome:R-HSA-9029569|refseq:NP_001140160.1|refseq:NP_060903.2|refseq:XP_016859982.1|dip:DIP-53661N ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|intact:EBI-1057697(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:XF6xqiiGohV0b2e/bzVx+J0XH7I9606 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 rigid:5dfw1d5Q+yUsXkdXBpHXnzpERyA false flag tag:n-n|sufficient binding region:214-306|mutation disrupting interaction strength:264-264 ha tag:n-n|sufficient binding region:231-317 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O75582 uniprotkb:Q9Y4C1 intact:EBI-73869|uniprotkb:O95316|uniprotkb:Q96AF7|uniprotkb:B7Z2Y5|intact:EBI-14183507|intact:EBI-12850788|ensembl:ENSP00000479667 intact:EBI-2515339|ensembl:ENSP00000323659|ensembl:ENSP00000386516|ensembl:ENSP00000386660|uniprotkb:Q68UT9|uniprotkb:Q8IY08|uniprotkb:Q68D47|uniprotkb:Q53S72|uniprotkb:Q6N050|uniprotkb:D6W5M3 psi-mi:ks6a5_human(display_long)|uniprotkb:Nuclear mitogen- and stress-activated protein kinase 1(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 5(gene name synonym)|uniprotkb:RSK-like protein kinase(gene name synonym)|uniprotkb:RPS6KA5(gene name)|psi-mi:RPS6KA5(display_short)|uniprotkb:MSK1(gene name synonym) psi-mi:kdm3a_human(display_long)|uniprotkb:KDM3A(gene name)|psi-mi:KDM3A(display_short)|uniprotkb:JHDM2A(gene name synonym)|uniprotkb:JMJD1(gene name synonym)|uniprotkb:JMJD1A(gene name synonym)|uniprotkb:KIAA0742(gene name synonym)|uniprotkb:TSGA(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2A(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1A(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3A"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cheng et al. (2014) pubmed:25535969|doi:10.1371/journal.pbio.1002026|imex:IM-24092 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16136249|imex:IM-24092-14|dip:DIP-198518E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004746.2|refseq:NP_872198.1|refseq:NP_001309164.1|refseq:NP_001309166.1|dip:DIP-30894N|ensembl:ENSG00000100784(gene)|ensembl:ENST00000614987(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043987"(histone H3-S10 phosphorylation)|go:"GO:0043988"(histone H3-S28 phosphorylation)|go:"GO:0043990"(histone H2A-S1 phosphorylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:O75582|rcsb pdb:1VZO|rcsb pdb:3KN5|rcsb pdb:3KN6|reactome:R-HSA-198753|reactome:R-HSA-199920|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-5621575 ensembl:ENSG00000115548(gene)|ensembl:ENST00000312912(transcript)|ensembl:ENST00000409064(transcript)|ensembl:ENST00000409556(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0000785"(chromatin)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046293"(formaldehyde biosynthetic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9Y4C1|reactome:R-HSA-3214842|reactome:R-HSA-9029569|refseq:NP_001140160.1|refseq:NP_060903.2|refseq:XP_016859982.1|dip:DIP-53661N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:8W2PRa/aVTLxiBJEbbXoebPqlco9606 rogid:XF6xqiiGohV0b2e/bzVx+J0XH7I9606 rigid:pCKbjm/grF23d11OljJV/pX/pYY false - flag tag:n-n|sufficient binding region:214-306 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)