#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q60793	uniprotkb:P46938	intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255	intact:EBI-1211949|uniprotkb:Q91WL1|uniprotkb:Q52KJ5|ensembl:ENSMUSP00000069554	psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym)	psi-mi:yap1_mouse(display_long)|uniprotkb:Yap1(gene name)|psi-mi:Yap1(display_short)|uniprotkb:Yap(gene name synonym)|uniprotkb:Yap65(gene name synonym)|uniprotkb:Protein yorkie homolog(gene name synonym)|uniprotkb:Yes-associated protein YAP65 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Imajo et al. (2015)	pubmed:25531778|doi:10.1038/ncb3084|imex:IM-24445	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16135411|imex:IM-24445-1|dip:DIP-199164E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N	refseq:NP_001164618.1|refseq:NP_033560.1|dip:DIP-40015N|ensembl:ENSMUSG00000053110(gene)|ensembl:ENSMUST00000065353(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0001824"(blastocyst development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003015"(heart process)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060242"(contact inhibition)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:P46938|rcsb pdb:3JUA|rcsb pdb:6JK0|rcsb pdb:6JK1|reactome:R-MMU-1251985|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-8939236|reactome:R-MMU-8951671|go:"GO:0035329"(hippo signaling)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/08	2017/08/10	rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090	rogid:3HcM3+sEb7cqRcBxi3jCxXRjT1810090	rigid:EpsowhpMSqCJ/QcP9SEwj4DRl94	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P46937	uniprotkb:Q60793	intact:EBI-1044059|uniprotkb:Q7Z574|uniprotkb:Q8IUY9|ensembl:ENSP00000282441|intact:EBI-28992622|uniprotkb:B7ZA01|uniprotkb:E3WEB5|uniprotkb:E3WEB6|uniprotkb:E9PRV2|uniprotkb:F5H202|uniprotkb:K0KQ18|uniprotkb:K0KYZ8|uniprotkb:K0L195|uniprotkb:K0L1G3|uniprotkb:B4DTY1	intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255	psi-mi:yap1_human(display_long)|uniprotkb:YAP1(gene name)|psi-mi:YAP1(display_short)|uniprotkb:YAP65(gene name synonym)|uniprotkb:Protein yorkie homolog(gene name synonym)|uniprotkb:Yes-associated protein YAP65 homolog(gene name synonym)	psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Imajo et al. (2015)	pubmed:25531778|doi:10.1038/ncb3084|imex:IM-24445	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16135428|imex:IM-24445-2|dip:DIP-199165E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269026.1|ensembl:ENST00000282441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003015"(heart process)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|ensembl:ENSG00000137693(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035329"(hippo signaling)|go:"GO:0042060"(wound healing)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050847"(progesterone receptor signaling pathway)|refseq:NP_001123617.1|refseq:NP_001181973.1|refseq:NP_001181974.1|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:P46937|rcsb pdb:1JMQ|rcsb pdb:1K5R|rcsb pdb:1K9Q|rcsb pdb:1K9R|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LTV|rcsb pdb:2LTW|rcsb pdb:3KYS|rcsb pdb:3MHR|rcsb pdb:4RE1|rcsb pdb:4REX|rcsb pdb:5OAQ|rcsb pdb:5YDX|rcsb pdb:5YDY|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6G8Q|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|go:"GO:0070064"(proline-rich region binding)|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6HIL|rcsb pdb:6Q2X|reactome:R-HSA-1251985|reactome:R-HSA-2028269|reactome:R-HSA-2032785|reactome:R-HSA-8939236|reactome:R-HSA-8940973|reactome:R-HSA-8951671|reactome:R-HSA-9619665|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060242"(contact inhibition)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0065003"(protein-containing complex assembly)|ensembl:ENSP00000282441|ensembl:ENST00000345877|ensembl:ENSP00000331023|ensembl:ENST00000524575|ensembl:ENSP00000435602|ensembl:ENST00000526343|refseq:NP_001269027.1|refseq:NP_001269028.1|refseq:NP_001269029.1|refseq:NP_001269030.1|ensembl:ENSP00000434134|ensembl:ENST00000531439|ensembl:ENSP00000431574|ensembl:ENSP00000487519|ensembl:ENST00000537274|ensembl:ENSP00000445635|ensembl:ENST00000615667|ensembl:ENSP00000478927|ensembl:ENST00000629586|dip:DIP-40839N	ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:bDNDhtCh5Qjdk1+PNM8Qb/340A09606	rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090	rigid:MUM8TirCz9UKoKF3jcL7tjX2Mw0	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O43474	uniprotkb:P46937	intact:EBI-7232405|uniprotkb:B3KT79|uniprotkb:Q9UNP3|uniprotkb:Q5T3J9|uniprotkb:P78338|uniprotkb:B2R8S4|uniprotkb:L0R3I6|uniprotkb:Q5T3J8|uniprotkb:Q8N717|uniprotkb:L0R4N5|intact:MINT-7261942	intact:EBI-1044059|uniprotkb:Q7Z574|uniprotkb:Q8IUY9|ensembl:ENSP00000282441|intact:EBI-28992622|uniprotkb:B7ZA01|uniprotkb:E3WEB5|uniprotkb:E3WEB6|uniprotkb:E9PRV2|uniprotkb:F5H202|uniprotkb:K0KQ18|uniprotkb:K0KYZ8|uniprotkb:K0L195|uniprotkb:K0L1G3|uniprotkb:B4DTY1	psi-mi:klf4_human(display_long)|uniprotkb:KLF4(gene name)|psi-mi:KLF4(display_short)|uniprotkb:EZF(gene name synonym)|uniprotkb:GKLF(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym)	psi-mi:yap1_human(display_long)|uniprotkb:YAP1(gene name)|psi-mi:YAP1(display_short)|uniprotkb:YAP65(gene name synonym)|uniprotkb:Protein yorkie homolog(gene name synonym)|uniprotkb:Yes-associated protein YAP65 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Imajo et al. (2015)	pubmed:25531778|doi:10.1038/ncb3084|imex:IM-24445	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16135449|imex:IM-24445-3|dip:DIP-199166E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:O43474|refseq:NP_001300981.1|refseq:NP_004226.3|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-381340|reactome:R-HSA-422085|reactome:R-HSA-452723|reactome:R-HSA-9617828|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|dip:DIP-57667N	refseq:NP_001269026.1|ensembl:ENST00000282441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003015"(heart process)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|ensembl:ENSG00000137693(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035329"(hippo signaling)|go:"GO:0042060"(wound healing)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050847"(progesterone receptor signaling pathway)|refseq:NP_001123617.1|refseq:NP_001181973.1|refseq:NP_001181974.1|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:P46937|rcsb pdb:1JMQ|rcsb pdb:1K5R|rcsb pdb:1K9Q|rcsb pdb:1K9R|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LTV|rcsb pdb:2LTW|rcsb pdb:3KYS|rcsb pdb:3MHR|rcsb pdb:4RE1|rcsb pdb:4REX|rcsb pdb:5OAQ|rcsb pdb:5YDX|rcsb pdb:5YDY|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6G8Q|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|go:"GO:0070064"(proline-rich region binding)|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6HIL|rcsb pdb:6Q2X|reactome:R-HSA-1251985|reactome:R-HSA-2028269|reactome:R-HSA-2032785|reactome:R-HSA-8939236|reactome:R-HSA-8940973|reactome:R-HSA-8951671|reactome:R-HSA-9619665|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060242"(contact inhibition)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0065003"(protein-containing complex assembly)|ensembl:ENSP00000282441|ensembl:ENST00000345877|ensembl:ENSP00000331023|ensembl:ENST00000524575|ensembl:ENSP00000435602|ensembl:ENST00000526343|refseq:NP_001269027.1|refseq:NP_001269028.1|refseq:NP_001269029.1|refseq:NP_001269030.1|ensembl:ENSP00000434134|ensembl:ENST00000531439|ensembl:ENSP00000431574|ensembl:ENSP00000487519|ensembl:ENST00000537274|ensembl:ENSP00000445635|ensembl:ENST00000615667|ensembl:ENSP00000478927|ensembl:ENST00000629586|dip:DIP-40839N	psi-mi:"MI:0465"(dip)	comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:JQTLvnhrXl3lhpcsps32NEz9F8I9606	rogid:bDNDhtCh5Qjdk1+PNM8Qb/340A09606	rigid:BtvbFoGC29VH3m1D245uK8M8XMg	false	his tag:n-n	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)