#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P62943	uniprotkb:P11716	intact:EBI-16134925|uniprotkb:P20071|uniprotkb:Q9H103|uniprotkb:Q9H566	intact:EBI-6477441	psi-mi:fkb1a_rabit(display_long)|uniprotkb:FKBP1A(gene name)|psi-mi:FKBP1A(display_short)|uniprotkb:FKBP1(gene name synonym)|uniprotkb:FKBP12(gene name synonym)|uniprotkb:12 kDa FK506-binding protein(gene name synonym)|uniprotkb:Calstabin-1(gene name synonym)|uniprotkb:FK506-binding protein 1A(gene name synonym)|uniprotkb:Immunophilin FKBP12(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	psi-mi:ryr1_rabit(display_long)|uniprotkb:RYR1(gene name)|psi-mi:RYR1(display_short)|uniprotkb:Skeletal muscle calcium release channel(gene name synonym)|uniprotkb:Skeletal muscle ryanodine receptor(gene name synonym)|uniprotkb:Skeletal muscle-type ryanodine receptor(gene name synonym)|uniprotkb:Type 1 ryanodine receptor(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Yan et al. (2015)	pubmed:25517095|doi:10.1038/nature14063|imex:IM-24326	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16134959|imex:IM-24326-1|dip:DIP-198931E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014802"(terminal cisterna)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0031312"(extrinsic component of organelle membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:3J8H|rcsb pdb:5GKY|rcsb pdb:5GKZ|rcsb pdb:5GL0|rcsb pdb:5GL1|refseq:NP_001164597.1|dip:DIP-61479N	go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR033215|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|rcsb pdb:2BCX|rcsb pdb:2XOA|rcsb pdb:3HSM|rcsb pdb:3ILA|rcsb pdb:3J8H|rcsb pdb:3RQR|rcsb pdb:4ERT|rcsb pdb:4ESU|rcsb pdb:4ETT|go:"GO:0035381"(ATP-gated ion channel activity)|rcsb pdb:4ETU|rcsb pdb:4I0Y|rcsb pdb:4I1E|go:"GO:0042802"(identical protein binding)|rcsb pdb:4I2S|rcsb pdb:4I37|go:"GO:0043588"(skin development)|go:"GO:0043931"(ossification involved in bone maturation)|rcsb pdb:4I3N|rcsb pdb:4I6I|rcsb pdb:4I7I|rcsb pdb:4I8M|rcsb pdb:4I96|rcsb pdb:4P9J|rcsb pdb:4UWA|go:"GO:0044325"(transmembrane transporter binding)|rcsb pdb:4UWE|rcsb pdb:5C30|rcsb pdb:5GKY|rcsb pdb:5GKZ|rcsb pdb:5GL0|rcsb pdb:5GL1|rcsb pdb:5J8V|rcsb pdb:5T15|rcsb pdb:5T9M|rcsb pdb:5T9N|rcsb pdb:5T9R|rcsb pdb:5T9S|rcsb pdb:5T9V|rcsb pdb:5TA3|rcsb pdb:5TAL|rcsb pdb:5TAM|rcsb pdb:5TAN|rcsb pdb:5TAP|rcsb pdb:5TAQ|rcsb pdb:5TAS|rcsb pdb:5TAT|rcsb pdb:5TAU|rcsb pdb:5TAV|rcsb pdb:5TAW|rcsb pdb:5TAX|rcsb pdb:5TAY|rcsb pdb:5TAZ|rcsb pdb:5TB0|rcsb pdb:5TB1|rcsb pdb:5TB2|rcsb pdb:5TB3|rcsb pdb:5TB4|rcsb pdb:6FG3|rcsb pdb:6FOO|rcsb pdb:6M2W|rcsb pdb:6WOT|rcsb pdb:7CF9|refseq:NP_001095188.1|dip:DIP-41872N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:3eikHNIIVs8AFM7PYVWurI/9KUY9986	rogid:QUlch7kTlopwGM10g+OXd4rODXo9986	rigid:V3HzHFghPCkrbd3m58rxgq3CRSo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P62943	uniprotkb:P11716	intact:EBI-16134925|uniprotkb:P20071|uniprotkb:Q9H103|uniprotkb:Q9H566	intact:EBI-6477441	psi-mi:fkb1a_rabit(display_long)|uniprotkb:FKBP1A(gene name)|psi-mi:FKBP1A(display_short)|uniprotkb:FKBP1(gene name synonym)|uniprotkb:FKBP12(gene name synonym)|uniprotkb:12 kDa FK506-binding protein(gene name synonym)|uniprotkb:Calstabin-1(gene name synonym)|uniprotkb:FK506-binding protein 1A(gene name synonym)|uniprotkb:Immunophilin FKBP12(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	psi-mi:ryr1_rabit(display_long)|uniprotkb:RYR1(gene name)|psi-mi:RYR1(display_short)|uniprotkb:Skeletal muscle calcium release channel(gene name synonym)|uniprotkb:Skeletal muscle ryanodine receptor(gene name synonym)|uniprotkb:Skeletal muscle-type ryanodine receptor(gene name synonym)|uniprotkb:Type 1 ryanodine receptor(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Yan et al. (2015)	pubmed:25517095|doi:10.1038/nature14063|imex:IM-24326	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16134976|imex:IM-24326-2|dip:DIP-198931E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014802"(terminal cisterna)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0031312"(extrinsic component of organelle membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:3J8H|rcsb pdb:5GKY|rcsb pdb:5GKZ|rcsb pdb:5GL0|rcsb pdb:5GL1|refseq:NP_001164597.1|dip:DIP-61479N	go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR033215|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|rcsb pdb:2BCX|rcsb pdb:2XOA|rcsb pdb:3HSM|rcsb pdb:3ILA|rcsb pdb:3J8H|rcsb pdb:3RQR|rcsb pdb:4ERT|rcsb pdb:4ESU|rcsb pdb:4ETT|go:"GO:0035381"(ATP-gated ion channel activity)|rcsb pdb:4ETU|rcsb pdb:4I0Y|rcsb pdb:4I1E|go:"GO:0042802"(identical protein binding)|rcsb pdb:4I2S|rcsb pdb:4I37|go:"GO:0043588"(skin development)|go:"GO:0043931"(ossification involved in bone maturation)|rcsb pdb:4I3N|rcsb pdb:4I6I|rcsb pdb:4I7I|rcsb pdb:4I8M|rcsb pdb:4I96|rcsb pdb:4P9J|rcsb pdb:4UWA|go:"GO:0044325"(transmembrane transporter binding)|rcsb pdb:4UWE|rcsb pdb:5C30|rcsb pdb:5GKY|rcsb pdb:5GKZ|rcsb pdb:5GL0|rcsb pdb:5GL1|rcsb pdb:5J8V|rcsb pdb:5T15|rcsb pdb:5T9M|rcsb pdb:5T9N|rcsb pdb:5T9R|rcsb pdb:5T9S|rcsb pdb:5T9V|rcsb pdb:5TA3|rcsb pdb:5TAL|rcsb pdb:5TAM|rcsb pdb:5TAN|rcsb pdb:5TAP|rcsb pdb:5TAQ|rcsb pdb:5TAS|rcsb pdb:5TAT|rcsb pdb:5TAU|rcsb pdb:5TAV|rcsb pdb:5TAW|rcsb pdb:5TAX|rcsb pdb:5TAY|rcsb pdb:5TAZ|rcsb pdb:5TB0|rcsb pdb:5TB1|rcsb pdb:5TB2|rcsb pdb:5TB3|rcsb pdb:5TB4|rcsb pdb:6FG3|rcsb pdb:6FOO|rcsb pdb:6M2W|rcsb pdb:6WOT|rcsb pdb:7CF9|refseq:NP_001095188.1|dip:DIP-41872N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:3eikHNIIVs8AFM7PYVWurI/9KUY9986	rogid:QUlch7kTlopwGM10g+OXd4rODXo9986	rigid:V3HzHFghPCkrbd3m58rxgq3CRSo	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)