#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P68139	uniprotkb:P41832	intact:EBI-3058728|ensembl:ENSGALP00000060685|uniprotkb:P02568|uniprotkb:P99020	intact:EBI-3692|uniprotkb:O13450|uniprotkb:D6W0S3|ensemblfungi:YNL271C	psi-mi:acts_chick(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:bni1_yeast(display_long)|uniprotkb:PPF3(gene name synonym)|uniprotkb:SHE5(gene name synonym)|uniprotkb:BNI1(gene name)|psi-mi:BNI1(display_short)|uniprotkb:YNL271C(locus name)|uniprotkb:N0646(orf name)|uniprotkb:Synthetic lethal 39(gene name synonym)|uniprotkb:Sensitive to high expression protein 5(gene name synonym)|uniprotkb:Pointed projection formation protein 3(gene name synonym)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Baker et al. (2015)	pubmed:25482541|doi:10.1016/j.str.2014.10.014|imex:IM-24188	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16132140|imex:IM-24188-1|dip:DIP-198707E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:7BTI|rcsb pdb:7K20|rcsb pdb:7K21|rcsb pdb:7KCH|rcsb pdb:6D8C|rcsb pdb:6DJM|rcsb pdb:6DJN|rcsb pdb:6DJO|rcsb pdb:6M5G|rcsb pdb:6UPV|rcsb pdb:6UPW|rcsb pdb:6X5Z|rcsb pdb:7BT7|rcsb pdb:7BTE|ensembl:ENSGALG00000011086(gene)|ensembl:ENSGALT00000088724(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005524"(ATP binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0048741"(skeletal muscle fiber development)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1MDU|rcsb pdb:5YU8|refseq:NP_001026234.1|dip:DIP-41824N|refseq:XP_015139542.1	refseq:NP_014128.2|sgd:S000005215|dip:DIP-974N|ensemblfungi:YNL271C(gene)|ensemblfungi:YNL271C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000133"(polarisome)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070649"(formin-nucleated actin cable assembly)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903827"|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|rcsb pdb:1UX4|rcsb pdb:1UX5|rcsb pdb:1Y64	psi-mi:"MI:0465"(dip)	-	crc64:0C5A9D5280A5858F	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49031	rogid:aS6XG+rT9RfN7DLRaqtiNywyVro559292	rigid:GZhJKr3ezltjdn4bUhUgTeeoXns	false	pyrene label:376-376	sufficient binding region:1312-1766|mutation decreasing interaction strength:1467-1467,1423-1423|mutation decreasing interaction strength:1423-1423|mutation decreasing interaction strength:1467-1467	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68139	uniprotkb:P41832	intact:EBI-3058728|ensembl:ENSGALP00000060685|uniprotkb:P02568|uniprotkb:P99020	intact:EBI-3692|uniprotkb:O13450|uniprotkb:D6W0S3|ensemblfungi:YNL271C	psi-mi:acts_chick(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:bni1_yeast(display_long)|uniprotkb:PPF3(gene name synonym)|uniprotkb:SHE5(gene name synonym)|uniprotkb:BNI1(gene name)|psi-mi:BNI1(display_short)|uniprotkb:YNL271C(locus name)|uniprotkb:N0646(orf name)|uniprotkb:Synthetic lethal 39(gene name synonym)|uniprotkb:Sensitive to high expression protein 5(gene name synonym)|uniprotkb:Pointed projection formation protein 3(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Baker et al. (2015)	pubmed:25482541|doi:10.1016/j.str.2014.10.014|imex:IM-24188	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16132171|imex:IM-24188-2|dip:DIP-198707E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:7BTI|rcsb pdb:7K20|rcsb pdb:7K21|rcsb pdb:7KCH|rcsb pdb:6D8C|rcsb pdb:6DJM|rcsb pdb:6DJN|rcsb pdb:6DJO|rcsb pdb:6M5G|rcsb pdb:6UPV|rcsb pdb:6UPW|rcsb pdb:6X5Z|rcsb pdb:7BT7|rcsb pdb:7BTE|ensembl:ENSGALG00000011086(gene)|ensembl:ENSGALT00000088724(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005524"(ATP binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0048741"(skeletal muscle fiber development)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1MDU|rcsb pdb:5YU8|refseq:NP_001026234.1|dip:DIP-41824N|refseq:XP_015139542.1	refseq:NP_014128.2|sgd:S000005215|dip:DIP-974N|ensemblfungi:YNL271C(gene)|ensemblfungi:YNL271C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000133"(polarisome)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070649"(formin-nucleated actin cable assembly)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903827"|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|rcsb pdb:1UX4|rcsb pdb:1UX5|rcsb pdb:1Y64	psi-mi:"MI:0465"(dip)	-	crc64:0C5A9D5280A5858F	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49031	rogid:aS6XG+rT9RfN7DLRaqtiNywyVro559292	rigid:GZhJKr3ezltjdn4bUhUgTeeoXns	false	oregon green label:376-376	sufficient binding region:1312-1766|mutation decreasing interaction strength:1467-1467,1423-1423|mutation decreasing interaction strength:1423-1423|mutation decreasing interaction strength:1467-1467	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)