#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:I4ENP2	uniprotkb:P61769-PRO_0000018779	intact:EBI-6163561|uniprotkb:O62917|uniprotkb:P30497|uniprotkb:P79496|uniprotkb:Q29679|uniprotkb:Q5QT24	intact:EBI-13942645	psi-mi:1b57_human(display_long)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:Bw-57(gene name synonym)|uniprotkb:HLAB(gene name synonym)|uniprotkb:MHC class I antigen B*57(gene name synonym)	psi-mi:p61769-pro_0000018779(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Saunders et al. (2015)	imex:IM-25706|pubmed:25480565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13942632|imex:IM-25706-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0055038"(recycling endosome membrane)|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:5T6Y|interpro:IPR036179|interpro:IPR037055|rcsb pdb:5U98|rcsb pdb:3WUW|ensembl:ENSG00000224608|ensembl:ENSP00000405178|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|uniprotkb:P01889(see-also)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0050776"(regulation of immune response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2HJL|rcsb pdb:2RFX|rcsb pdb:3VH8|go:"GO:0009986"(cell surface)|rcsb pdb:3UPR|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:2YPK|rcsb pdb:2YPL|go:"GO:0042605"(peptide antigen binding)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:6BXP|rcsb pdb:6BXQ|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000435618|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T	intact:EBI-714718(chain-parent)	-	no-uniprot-update:|caution:"The protein could not be merged with EBI-1046513 because of some conflicts with the protein sequence (features which cannot be shifted)."	chain-seq-start:21|chain-seq-end:119	figure legend:Table 1|comment:B5701 allele|kinetics:Kd for the HLA-B5701 Ile104Asn mutant was >300uM|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:28.0x10^-6(molar)	2017/02/21	2017/03/30	rogid:x0dOWdHQKXpKleDLGPQxYfSGjLI9606	rogid:PHSGrRweGYBm8t9Sd55DncdrnO49606	rigid:Lw9BHpGZP5P/Ow96iukM/ZrJQBI	false	mutation decreasing interaction strength:106-106|mutation disrupting interaction strength:107-107|mutation disrupting interaction strength:104-104,106-106|mutation disrupting interaction strength:104-104,107-107|sufficient binding region:25-300|mutation decreasing interaction strength:104-104	sufficient binding region:1-99	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I4ENP2	uniprotkb:P43629	intact:EBI-6163561|uniprotkb:O62917|uniprotkb:P30497|uniprotkb:P79496|uniprotkb:Q29679|uniprotkb:Q5QT24	intact:EBI-3910993|uniprotkb:Q16541|uniprotkb:O43473|uniprotkb:Q14946|ensembl:ENSP00000375608|ensembl:ENSP00000492794|ensembl:ENSP00000484036|ensembl:ENSP00000484488|ensembl:ENSP00000484972|ensembl:ENSP00000491550	psi-mi:1b57_human(display_long)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:Bw-57(gene name synonym)|uniprotkb:HLAB(gene name synonym)|uniprotkb:MHC class I antigen B*57(gene name synonym)	psi-mi:ki3l1_human(display_long)|uniprotkb:KIR3DL1(gene name)|psi-mi:KIR3DL1(display_short)|uniprotkb:CD158E(gene name synonym)|uniprotkb:NKAT3(gene name synonym)|uniprotkb:NKB1(gene name synonym)|uniprotkb:CD158 antigen-like family member E(gene name synonym)|uniprotkb:HLA-BW4-specific inhibitory NK cell receptor(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 3(gene name synonym)|uniprotkb:p70 natural killer cell receptor clones CL-2/CL-11(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Saunders et al. (2015)	imex:IM-25706|pubmed:25480565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13942632|imex:IM-25706-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0055038"(recycling endosome membrane)|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:5T6Y|interpro:IPR036179|interpro:IPR037055|rcsb pdb:5U98|rcsb pdb:3WUW|ensembl:ENSG00000224608|ensembl:ENSP00000405178|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|uniprotkb:P01889(see-also)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0050776"(regulation of immune response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2HJL|rcsb pdb:2RFX|rcsb pdb:3VH8|go:"GO:0009986"(cell surface)|rcsb pdb:3UPR|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:2YPK|rcsb pdb:2YPL|go:"GO:0042605"(peptide antigen binding)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:6BXP|rcsb pdb:6BXQ|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000435618|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T	refseq:NP_037421.2|refseq:NP_001309097.1|ensembl:ENSG00000167633(gene)|ensembl:ENSG00000274036(gene)|ensembl:ENSG00000275288(gene)|ensembl:ENSG00000276423(gene)|ensembl:ENSG00000284342(gene)|ensembl:ENSG00000284426(gene)|ensembl:ENST00000391728(transcript)|ensembl:ENST00000612668(transcript)|ensembl:ENST00000616188(transcript)|ensembl:ENST00000621353(transcript)|ensembl:ENST00000639353(transcript)|ensembl:ENST00000640788(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0030109"(HLA-B specific inhibitory MHC class I receptor activity)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:6V3J|rcsb pdb:7K80|reactome:R-HSA-198933	-	no-uniprot-update:|caution:"The protein could not be merged with EBI-1046513 because of some conflicts with the protein sequence (features which cannot be shifted)."	-	figure legend:Table 1|comment:B5701 allele|kinetics:Kd for the HLA-B5701 Ile104Asn mutant was >300uM|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:28.0x10^-6(molar)	2017/02/21	2017/03/30	rogid:x0dOWdHQKXpKleDLGPQxYfSGjLI9606	rogid:hmkzMYVXr2As+kkOTVcl5L262l09606	rigid:Lw9BHpGZP5P/Ow96iukM/ZrJQBI	false	mutation decreasing interaction strength:106-106|mutation disrupting interaction strength:107-107|mutation disrupting interaction strength:104-104,106-106|mutation disrupting interaction strength:104-104,107-107|sufficient binding region:25-300|mutation decreasing interaction strength:104-104	tag:n-n|sufficient binding region:22-320	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I4ENP2	uniprotkb:P01834	intact:EBI-6163561|uniprotkb:O62917|uniprotkb:P30497|uniprotkb:P79496|uniprotkb:Q29679|uniprotkb:Q5QT24	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:1b57_human(display_long)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:Bw-57(gene name synonym)|uniprotkb:HLAB(gene name synonym)|uniprotkb:MHC class I antigen B*57(gene name synonym)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Saunders et al. (2015)	imex:IM-25706|pubmed:25480565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13942632|imex:IM-25706-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0055038"(recycling endosome membrane)|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:5T6Y|interpro:IPR036179|interpro:IPR037055|rcsb pdb:5U98|rcsb pdb:3WUW|ensembl:ENSG00000224608|ensembl:ENSP00000405178|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|uniprotkb:P01889(see-also)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0050776"(regulation of immune response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2HJL|rcsb pdb:2RFX|rcsb pdb:3VH8|go:"GO:0009986"(cell surface)|rcsb pdb:3UPR|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:2YPK|rcsb pdb:2YPL|go:"GO:0042605"(peptide antigen binding)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:6BXP|rcsb pdb:6BXQ|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000435618|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T	rcsb pdb:2NY7|rcsb pdb:1N0X|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:4D3C|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:5ESV|rcsb pdb:5ESZ|reactome:R-HSA-5690714|rcsb pdb:6OGE|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1UCB|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:5B39|rcsb pdb:5B38|reactome:R-HSA-202733|rcsb pdb:3U0W|rcsb pdb:1DFB|rcsb pdb:3WUW|rcsb pdb:1HZH|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:4D9R|rcsb pdb:4HIX|go:"GO:0001895"(retina homeostasis)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:1CLY|rcsb pdb:1GAF|rcsb pdb:2RFX|rcsb pdb:3IU3|rcsb pdb:3RU8|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-983695|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|reactome:R-HSA-977606|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:5VEB|rcsb pdb:5VIY|interpro:IPR036179|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6OKP|reactome:R-HSA-9664323|reactome:R-HSA-9664422	-	no-uniprot-update:|caution:"The protein could not be merged with EBI-1046513 because of some conflicts with the protein sequence (features which cannot be shifted)."	-	figure legend:Table 1|comment:B5701 allele|kinetics:Kd for the HLA-B5701 Ile104Asn mutant was >300uM|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:28.0x10^-6(molar)	2017/02/21	2017/03/30	rogid:x0dOWdHQKXpKleDLGPQxYfSGjLI9606	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	rigid:Lw9BHpGZP5P/Ow96iukM/ZrJQBI	false	mutation decreasing interaction strength:106-106|mutation disrupting interaction strength:107-107|mutation disrupting interaction strength:104-104,106-106|mutation disrupting interaction strength:104-104,107-107|sufficient binding region:25-300|mutation decreasing interaction strength:104-104	sufficient binding region:94-102	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-22097925	uniprotkb:P61769-PRO_0000018779	intact:Q5SS57|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|intact:EBI-1054175|intact:EBI-1047909|intact:EBI-8770324|intact:EBI-6163582|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548	intact:EBI-13942645	psi-mi:1b08_human_deprecated(display_short)|psi-mi:EBI-22097925(display_long)|uniprotkb:MHC class I antigen B*8(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	psi-mi:p61769-pro_0000018779(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Saunders et al. (2015)	imex:IM-25706|pubmed:25480565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13942785|imex:IM-25706-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042605"(peptide antigen binding)|uniprotkb:P01889(see-also)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0051087"(chaperone binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050776"(regulation of immune response)|ensembl:ENST00000425848|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1M05|rcsb pdb:1MI5|rcsb pdb:3FFC|go:"GO:0009986"(cell surface)|go:"GO:0046977"(TAP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0006955"(immune response)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|rcsb pdb:3SJV|rcsb pdb:3SPV|rcsb pdb:3SKM|rcsb pdb:3SKO|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0016020"(membrane)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:4QRU|ensembl:ENSG00000223532|ensembl:ENSP00000400842|rcsb pdb:4QRT|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4QRS|rcsb pdb:5WMQ|rcsb pdb:5WMR|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR036179|interpro:IPR037055	intact:EBI-714718(chain-parent)	-	no-uniprot-update:|caution:This protein is not up-to-date anymore with the uniprot protein because of feature conflicts.	chain-seq-start:21|chain-seq-end:119	figure legend:Table 1i|comment:B0801 allele|kinetics:Kd for the R106L mutant was >300uM|comment:No binding was shown by the wild type.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/21	2019/10/18	rogid:ETb4GSVbIeY/xGTH8CTp9P/y3GA9606	rogid:PHSGrRweGYBm8t9Sd55DncdrnO49606	rigid:RNck/E9DRHHqjXr/X2sLVL4DfVQ	false	mutation causing an interaction:104-104,106-107|sufficient binding region:25-300	sufficient binding region:1-99	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-22097925	uniprotkb:P43629	intact:Q5SS57|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|intact:EBI-1054175|intact:EBI-1047909|intact:EBI-8770324|intact:EBI-6163582|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548	intact:EBI-3910993|uniprotkb:Q16541|uniprotkb:O43473|uniprotkb:Q14946|ensembl:ENSP00000375608|ensembl:ENSP00000492794|ensembl:ENSP00000484036|ensembl:ENSP00000484488|ensembl:ENSP00000484972|ensembl:ENSP00000491550	psi-mi:1b08_human_deprecated(display_short)|psi-mi:EBI-22097925(display_long)|uniprotkb:MHC class I antigen B*8(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	psi-mi:ki3l1_human(display_long)|uniprotkb:KIR3DL1(gene name)|psi-mi:KIR3DL1(display_short)|uniprotkb:CD158E(gene name synonym)|uniprotkb:NKAT3(gene name synonym)|uniprotkb:NKB1(gene name synonym)|uniprotkb:CD158 antigen-like family member E(gene name synonym)|uniprotkb:HLA-BW4-specific inhibitory NK cell receptor(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 3(gene name synonym)|uniprotkb:p70 natural killer cell receptor clones CL-2/CL-11(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Saunders et al. (2015)	imex:IM-25706|pubmed:25480565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13942785|imex:IM-25706-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042605"(peptide antigen binding)|uniprotkb:P01889(see-also)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0051087"(chaperone binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050776"(regulation of immune response)|ensembl:ENST00000425848|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1M05|rcsb pdb:1MI5|rcsb pdb:3FFC|go:"GO:0009986"(cell surface)|go:"GO:0046977"(TAP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0006955"(immune response)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|rcsb pdb:3SJV|rcsb pdb:3SPV|rcsb pdb:3SKM|rcsb pdb:3SKO|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0016020"(membrane)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:4QRU|ensembl:ENSG00000223532|ensembl:ENSP00000400842|rcsb pdb:4QRT|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4QRS|rcsb pdb:5WMQ|rcsb pdb:5WMR|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR036179|interpro:IPR037055	refseq:NP_037421.2|refseq:NP_001309097.1|ensembl:ENSG00000167633(gene)|ensembl:ENSG00000274036(gene)|ensembl:ENSG00000275288(gene)|ensembl:ENSG00000276423(gene)|ensembl:ENSG00000284342(gene)|ensembl:ENSG00000284426(gene)|ensembl:ENST00000391728(transcript)|ensembl:ENST00000612668(transcript)|ensembl:ENST00000616188(transcript)|ensembl:ENST00000621353(transcript)|ensembl:ENST00000639353(transcript)|ensembl:ENST00000640788(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0030109"(HLA-B specific inhibitory MHC class I receptor activity)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:3VH8|rcsb pdb:3WUW|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:6V3J|rcsb pdb:7K80|reactome:R-HSA-198933	-	no-uniprot-update:|caution:This protein is not up-to-date anymore with the uniprot protein because of feature conflicts.	-	figure legend:Table 1i|comment:B0801 allele|kinetics:Kd for the R106L mutant was >300uM|comment:No binding was shown by the wild type.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/21	2019/10/18	rogid:ETb4GSVbIeY/xGTH8CTp9P/y3GA9606	rogid:hmkzMYVXr2As+kkOTVcl5L262l09606	rigid:RNck/E9DRHHqjXr/X2sLVL4DfVQ	false	mutation causing an interaction:104-104,106-107|sufficient binding region:25-300	sufficient binding region:22-320|tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-22097925	uniprotkb:Q3KST2	intact:Q5SS57|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|intact:EBI-1054175|intact:EBI-1047909|intact:EBI-8770324|intact:EBI-6163582|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548	intact:EBI-2621171	psi-mi:1b08_human_deprecated(display_short)|psi-mi:EBI-22097925(display_long)|uniprotkb:MHC class I antigen B*8(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	psi-mi:ebna3_ebvg(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3A(gene name synonym)|uniprotkb:BLRF3-BERF1(orf name)|uniprotkb:EBNA3(gene name)|psi-mi:EBNA3(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Saunders et al. (2015)	imex:IM-25706|pubmed:25480565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13942785|imex:IM-25706-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042605"(peptide antigen binding)|uniprotkb:P01889(see-also)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0051087"(chaperone binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050776"(regulation of immune response)|ensembl:ENST00000425848|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1M05|rcsb pdb:1MI5|rcsb pdb:3FFC|go:"GO:0009986"(cell surface)|go:"GO:0046977"(TAP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0006955"(immune response)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|rcsb pdb:3SJV|rcsb pdb:3SPV|rcsb pdb:3SKM|rcsb pdb:3SKO|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0016020"(membrane)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:4QRU|ensembl:ENSG00000223532|ensembl:ENSP00000400842|rcsb pdb:4QRT|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4QRS|rcsb pdb:5WMQ|rcsb pdb:5WMR|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR036179|interpro:IPR037055	interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0016032"(viral process)|go:"GO:0044204"(host cell nuclear matrix)|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:1MI5	-	no-uniprot-update:|caution:This protein is not up-to-date anymore with the uniprot protein because of feature conflicts.	-	figure legend:Table 1i|comment:B0801 allele|kinetics:Kd for the R106L mutant was >300uM|comment:No binding was shown by the wild type.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/21	2019/10/18	rogid:ETb4GSVbIeY/xGTH8CTp9P/y3GA9606	rogid:FPF70ySrl9fMc4dITMEwtohfvYs10376	rigid:RNck/E9DRHHqjXr/X2sLVL4DfVQ	false	mutation causing an interaction:104-104,106-107|sufficient binding region:25-300	sufficient binding region:325-333	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-22097925	uniprotkb:Q3KST2	intact:Q5SS57|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|intact:EBI-1054175|intact:EBI-1047909|intact:EBI-8770324|intact:EBI-6163582|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548	intact:EBI-2621171	psi-mi:1b08_human_deprecated(display_short)|psi-mi:EBI-22097925(display_long)|uniprotkb:MHC class I antigen B*8(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	psi-mi:ebna3_ebvg(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3A(gene name synonym)|uniprotkb:BLRF3-BERF1(orf name)|uniprotkb:EBNA3(gene name)|psi-mi:EBNA3(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Saunders et al. (2015)	imex:IM-25706|pubmed:25480565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13942827|wwpdb:3X14|imex:IM-25706-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042605"(peptide antigen binding)|uniprotkb:P01889(see-also)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0051087"(chaperone binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050776"(regulation of immune response)|ensembl:ENST00000425848|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1M05|rcsb pdb:1MI5|rcsb pdb:3FFC|go:"GO:0009986"(cell surface)|go:"GO:0046977"(TAP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0006955"(immune response)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|rcsb pdb:3SJV|rcsb pdb:3SPV|rcsb pdb:3SKM|rcsb pdb:3SKO|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0016020"(membrane)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:4QRU|ensembl:ENSG00000223532|ensembl:ENSP00000400842|rcsb pdb:4QRT|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4QRS|rcsb pdb:5WMQ|rcsb pdb:5WMR|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR036179|interpro:IPR037055	interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0016032"(viral process)|go:"GO:0044204"(host cell nuclear matrix)|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:1MI5	-	no-uniprot-update:|caution:This protein is not up-to-date anymore with the uniprot protein because of feature conflicts.	-	figure legend:Table 2|comment:B0801 allele|3d-resolution:2A|3d-r-factors:R work = 0.178   R free  = 0.229|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/21	2019/10/18	rogid:ETb4GSVbIeY/xGTH8CTp9P/y3GA9606	rogid:FPF70ySrl9fMc4dITMEwtohfvYs10376	rigid:f8jw55DykEYmyeFYMpa/Fnlcxw8	false	mutation:104-104,106-107|sufficient binding region:25-300	sufficient binding region:325-333	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-22097925	uniprotkb:P61769-PRO_0000018779	intact:Q5SS57|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|intact:EBI-1054175|intact:EBI-1047909|intact:EBI-8770324|intact:EBI-6163582|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548	intact:EBI-13942645	psi-mi:1b08_human_deprecated(display_short)|psi-mi:EBI-22097925(display_long)|uniprotkb:MHC class I antigen B*8(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	psi-mi:p61769-pro_0000018779(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Saunders et al. (2015)	imex:IM-25706|pubmed:25480565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13942827|wwpdb:3X14|imex:IM-25706-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042605"(peptide antigen binding)|uniprotkb:P01889(see-also)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0051087"(chaperone binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050776"(regulation of immune response)|ensembl:ENST00000425848|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1M05|rcsb pdb:1MI5|rcsb pdb:3FFC|go:"GO:0009986"(cell surface)|go:"GO:0046977"(TAP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0006955"(immune response)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|rcsb pdb:3SJV|rcsb pdb:3SPV|rcsb pdb:3SKM|rcsb pdb:3SKO|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0016020"(membrane)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:4QRU|ensembl:ENSG00000223532|ensembl:ENSP00000400842|rcsb pdb:4QRT|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4QRS|rcsb pdb:5WMQ|rcsb pdb:5WMR|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR036179|interpro:IPR037055	intact:EBI-714718(chain-parent)	-	no-uniprot-update:|caution:This protein is not up-to-date anymore with the uniprot protein because of feature conflicts.	chain-seq-start:21|chain-seq-end:119	figure legend:Table 2|comment:B0801 allele|3d-resolution:2A|3d-r-factors:R work = 0.178   R free  = 0.229|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/21	2019/10/18	rogid:ETb4GSVbIeY/xGTH8CTp9P/y3GA9606	rogid:PHSGrRweGYBm8t9Sd55DncdrnO49606	rigid:f8jw55DykEYmyeFYMpa/Fnlcxw8	false	mutation:104-104,106-107|sufficient binding region:25-300	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I4ENP2	uniprotkb:P01834	intact:EBI-6163561|uniprotkb:O62917|uniprotkb:P30497|uniprotkb:P79496|uniprotkb:Q29679|uniprotkb:Q5QT24	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:1b57_human(display_long)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:Bw-57(gene name synonym)|uniprotkb:HLAB(gene name synonym)|uniprotkb:MHC class I antigen B*57(gene name synonym)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Saunders et al. (2015)	imex:IM-25706|pubmed:25480565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13942846|imex:IM-25706-4|wwpdb:3x11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0055038"(recycling endosome membrane)|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:5T6Y|interpro:IPR036179|interpro:IPR037055|rcsb pdb:5U98|rcsb pdb:3WUW|ensembl:ENSG00000224608|ensembl:ENSP00000405178|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|uniprotkb:P01889(see-also)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0050776"(regulation of immune response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2HJL|rcsb pdb:2RFX|rcsb pdb:3VH8|go:"GO:0009986"(cell surface)|rcsb pdb:3UPR|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:2YPK|rcsb pdb:2YPL|go:"GO:0042605"(peptide antigen binding)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:6BXP|rcsb pdb:6BXQ|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000435618|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T	rcsb pdb:2NY7|rcsb pdb:1N0X|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:4D3C|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:5ESV|rcsb pdb:5ESZ|reactome:R-HSA-5690714|rcsb pdb:6OGE|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1UCB|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:5B39|rcsb pdb:5B38|reactome:R-HSA-202733|rcsb pdb:3U0W|rcsb pdb:1DFB|rcsb pdb:3WUW|rcsb pdb:1HZH|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:4D9R|rcsb pdb:4HIX|go:"GO:0001895"(retina homeostasis)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:1CLY|rcsb pdb:1GAF|rcsb pdb:2RFX|rcsb pdb:3IU3|rcsb pdb:3RU8|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-983695|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|reactome:R-HSA-977606|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:5VEB|rcsb pdb:5VIY|interpro:IPR036179|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6OKP|reactome:R-HSA-9664323|reactome:R-HSA-9664422	-	no-uniprot-update:|caution:"The protein could not be merged with EBI-1046513 because of some conflicts with the protein sequence (features which cannot be shifted)."	-	figure legend:Table 2|comment:B5701 allele|3d-resolution:A 2.15|3d-r-factors:R work =0.19   R free  =0.23|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/21	2017/03/30	rogid:x0dOWdHQKXpKleDLGPQxYfSGjLI9606	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	rigid:VC7kdxbCZDZwdnVqCfCsmDZk7HI	false	mutation:104-104,106-106,107-107|sufficient binding region:25-300	sufficient binding region:94-102	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I4ENP2	uniprotkb:P61769-PRO_0000018779	intact:EBI-6163561|uniprotkb:O62917|uniprotkb:P30497|uniprotkb:P79496|uniprotkb:Q29679|uniprotkb:Q5QT24	intact:EBI-13942645	psi-mi:1b57_human(display_long)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:Bw-57(gene name synonym)|uniprotkb:HLAB(gene name synonym)|uniprotkb:MHC class I antigen B*57(gene name synonym)	psi-mi:p61769-pro_0000018779(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Saunders et al. (2015)	imex:IM-25706|pubmed:25480565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13942846|imex:IM-25706-4|wwpdb:3x11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0055038"(recycling endosome membrane)|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:5T6Y|interpro:IPR036179|interpro:IPR037055|rcsb pdb:5U98|rcsb pdb:3WUW|ensembl:ENSG00000224608|ensembl:ENSP00000405178|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|uniprotkb:P01889(see-also)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0050776"(regulation of immune response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2HJL|rcsb pdb:2RFX|rcsb pdb:3VH8|go:"GO:0009986"(cell surface)|rcsb pdb:3UPR|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:2YPK|rcsb pdb:2YPL|go:"GO:0042605"(peptide antigen binding)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:6BXP|rcsb pdb:6BXQ|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000435618|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T	intact:EBI-714718(chain-parent)	-	no-uniprot-update:|caution:"The protein could not be merged with EBI-1046513 because of some conflicts with the protein sequence (features which cannot be shifted)."	chain-seq-start:21|chain-seq-end:119	figure legend:Table 2|comment:B5701 allele|3d-resolution:A 2.15|3d-r-factors:R work =0.19   R free  =0.23|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/21	2017/03/30	rogid:x0dOWdHQKXpKleDLGPQxYfSGjLI9606	rogid:PHSGrRweGYBm8t9Sd55DncdrnO49606	rigid:VC7kdxbCZDZwdnVqCfCsmDZk7HI	false	mutation:104-104,106-106,107-107|sufficient binding region:25-300	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-22097925	uniprotkb:Q3KST2	intact:Q5SS57|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|intact:EBI-1054175|intact:EBI-1047909|intact:EBI-8770324|intact:EBI-6163582|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548	intact:EBI-2621171	psi-mi:1b08_human_deprecated(display_short)|psi-mi:EBI-22097925(display_long)|uniprotkb:MHC class I antigen B*8(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	psi-mi:ebna3_ebvg(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3A(gene name synonym)|uniprotkb:BLRF3-BERF1(orf name)|uniprotkb:EBNA3(gene name)|psi-mi:EBNA3(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Saunders et al. (2015)	imex:IM-25706|pubmed:25480565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10376(ebvg)|taxid:10376("Epstein-Barr virus (strain B95-8)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13942956|imex:IM-25706-5|pdbe:3X13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042605"(peptide antigen binding)|uniprotkb:P01889(see-also)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0051087"(chaperone binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050776"(regulation of immune response)|ensembl:ENST00000425848|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1M05|rcsb pdb:1MI5|rcsb pdb:3FFC|go:"GO:0009986"(cell surface)|go:"GO:0046977"(TAP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0006955"(immune response)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|rcsb pdb:3SJV|rcsb pdb:3SPV|rcsb pdb:3SKM|rcsb pdb:3SKO|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0016020"(membrane)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:4QRU|ensembl:ENSG00000223532|ensembl:ENSP00000400842|rcsb pdb:4QRT|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4QRS|rcsb pdb:5WMQ|rcsb pdb:5WMR|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR036179|interpro:IPR037055	interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|go:"GO:0016032"(viral process)|go:"GO:0044204"(host cell nuclear matrix)|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:1MI5	-	no-uniprot-update:|caution:This protein is not up-to-date anymore with the uniprot protein because of feature conflicts.	-	figure legend:Table 2|comment:B0801 allele|3d-resolution:1.8A|3d-r-factors:R work = 0.17   R free  = 0.21|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/21	2019/10/18	rogid:ETb4GSVbIeY/xGTH8CTp9P/y3GA9606	rogid:FPF70ySrl9fMc4dITMEwtohfvYs10376	rigid:f8jw55DykEYmyeFYMpa/Fnlcxw8	false	mutation:104-104|sufficient binding region:25-300	sufficient binding region:325-333	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-22097925	uniprotkb:P61769-PRO_0000018779	intact:Q5SS57|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|intact:EBI-1054175|intact:EBI-1047909|intact:EBI-8770324|intact:EBI-6163582|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548	intact:EBI-13942645	psi-mi:1b08_human_deprecated(display_short)|psi-mi:EBI-22097925(display_long)|uniprotkb:MHC class I antigen B*8(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)	psi-mi:p61769-pro_0000018779(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Saunders et al. (2015)	imex:IM-25706|pubmed:25480565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13942956|imex:IM-25706-5|pdbe:3X13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042605"(peptide antigen binding)|uniprotkb:P01889(see-also)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0051087"(chaperone binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050776"(regulation of immune response)|ensembl:ENST00000425848|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1M05|rcsb pdb:1MI5|rcsb pdb:3FFC|go:"GO:0009986"(cell surface)|go:"GO:0046977"(TAP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0006955"(immune response)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|rcsb pdb:3SJV|rcsb pdb:3SPV|rcsb pdb:3SKM|rcsb pdb:3SKO|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0016020"(membrane)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:4QRU|ensembl:ENSG00000223532|ensembl:ENSP00000400842|rcsb pdb:4QRT|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4QRS|rcsb pdb:5WMQ|rcsb pdb:5WMR|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR036179|interpro:IPR037055	intact:EBI-714718(chain-parent)	-	no-uniprot-update:|caution:This protein is not up-to-date anymore with the uniprot protein because of feature conflicts.	chain-seq-start:21|chain-seq-end:119	figure legend:Table 2|comment:B0801 allele|3d-resolution:1.8A|3d-r-factors:R work = 0.17   R free  = 0.21|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/21	2019/10/18	rogid:ETb4GSVbIeY/xGTH8CTp9P/y3GA9606	rogid:PHSGrRweGYBm8t9Sd55DncdrnO49606	rigid:f8jw55DykEYmyeFYMpa/Fnlcxw8	false	mutation:104-104|sufficient binding region:25-300	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I4ENP2	uniprotkb:P01834	intact:EBI-6163561|uniprotkb:O62917|uniprotkb:P30497|uniprotkb:P79496|uniprotkb:Q29679|uniprotkb:Q5QT24	intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130	psi-mi:1b57_human(display_long)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:Bw-57(gene name synonym)|uniprotkb:HLAB(gene name synonym)|uniprotkb:MHC class I antigen B*57(gene name synonym)	psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Saunders et al. (2015)	imex:IM-25706|pubmed:25480565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13942977|imex:IM-25706-6|wwpdb:3x12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0055038"(recycling endosome membrane)|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:5T6Y|interpro:IPR036179|interpro:IPR037055|rcsb pdb:5U98|rcsb pdb:3WUW|ensembl:ENSG00000224608|ensembl:ENSP00000405178|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|uniprotkb:P01889(see-also)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0050776"(regulation of immune response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2HJL|rcsb pdb:2RFX|rcsb pdb:3VH8|go:"GO:0009986"(cell surface)|rcsb pdb:3UPR|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:2YPK|rcsb pdb:2YPL|go:"GO:0042605"(peptide antigen binding)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:6BXP|rcsb pdb:6BXQ|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000435618|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T	rcsb pdb:2NY7|rcsb pdb:1N0X|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:4D3C|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:5ESV|rcsb pdb:5ESZ|reactome:R-HSA-5690714|rcsb pdb:6OGE|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1UCB|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:5B39|rcsb pdb:5B38|reactome:R-HSA-202733|rcsb pdb:3U0W|rcsb pdb:1DFB|rcsb pdb:3WUW|rcsb pdb:1HZH|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:4D9R|rcsb pdb:4HIX|go:"GO:0001895"(retina homeostasis)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:1CLY|rcsb pdb:1GAF|rcsb pdb:2RFX|rcsb pdb:3IU3|rcsb pdb:3RU8|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-983695|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|reactome:R-HSA-977606|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:5VEB|rcsb pdb:5VIY|interpro:IPR036179|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6OKP|reactome:R-HSA-9664323|reactome:R-HSA-9664422	-	no-uniprot-update:|caution:"The protein could not be merged with EBI-1046513 because of some conflicts with the protein sequence (features which cannot be shifted)."	-	figure legend:Table 2|comment:B5701 allele|3d-resolution:A 1.8|3d-r-factors:R work = 0.18  R free  = 0.22|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/21	2017/03/30	rogid:x0dOWdHQKXpKleDLGPQxYfSGjLI9606	rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606	rigid:VC7kdxbCZDZwdnVqCfCsmDZk7HI	false	sufficient binding region:25-300|mutation:104-104	sufficient binding region:94-102	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I4ENP2	uniprotkb:P61769-PRO_0000018779	intact:EBI-6163561|uniprotkb:O62917|uniprotkb:P30497|uniprotkb:P79496|uniprotkb:Q29679|uniprotkb:Q5QT24	intact:EBI-13942645	psi-mi:1b57_human(display_long)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:Bw-57(gene name synonym)|uniprotkb:HLAB(gene name synonym)|uniprotkb:MHC class I antigen B*57(gene name synonym)	psi-mi:p61769-pro_0000018779(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Saunders et al. (2015)	imex:IM-25706|pubmed:25480565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13942977|imex:IM-25706-6|wwpdb:3x12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0055038"(recycling endosome membrane)|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:5T6Y|interpro:IPR036179|interpro:IPR037055|rcsb pdb:5U98|rcsb pdb:3WUW|ensembl:ENSG00000224608|ensembl:ENSP00000405178|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|uniprotkb:P01889(see-also)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0050776"(regulation of immune response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2HJL|rcsb pdb:2RFX|rcsb pdb:3VH8|go:"GO:0009986"(cell surface)|rcsb pdb:3UPR|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:2YPK|rcsb pdb:2YPL|go:"GO:0042605"(peptide antigen binding)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:6BXP|rcsb pdb:6BXQ|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000435618|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T	intact:EBI-714718(chain-parent)	-	no-uniprot-update:|caution:"The protein could not be merged with EBI-1046513 because of some conflicts with the protein sequence (features which cannot be shifted)."	chain-seq-start:21|chain-seq-end:119	figure legend:Table 2|comment:B5701 allele|3d-resolution:A 1.8|3d-r-factors:R work = 0.18  R free  = 0.22|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/21	2017/03/30	rogid:x0dOWdHQKXpKleDLGPQxYfSGjLI9606	rogid:PHSGrRweGYBm8t9Sd55DncdrnO49606	rigid:VC7kdxbCZDZwdnVqCfCsmDZk7HI	false	sufficient binding region:25-300|mutation:104-104	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)