#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P11103 uniprotkb:Q3U2S4-1 intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3 intact:EBI-16131219|ensembl:ENSMUSP00000033494 psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:q3u2s4-1(display_long)|uniprotkb:Otud5(gene name)|psi-mi:Otud5(display_short)|uniprotkb:DXImx46e(gene name synonym)|uniprotkb:Sfc7(gene name synonym)|uniprotkb:Deubiquitinating enzyme A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Rutz et al. (2015) pubmed:25470037|doi:10.1038/nature13979|imex:IM-24397 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16131227|imex:IM-24397-1|dip:DIP-199025E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N ensembl:ENSMUSG00000031154(gene)|ensembl:ENSMUST00000033494(transcript)|intact:EBI-11021342(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/08 2017/08/10 rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090 rogid:u8wgRhTTWzY37qh+nvsaG3LyrKw10090 rigid:dW4pSsB8wV+SIeWGBaGROnTJpxI false - flag tag:?-? - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P51450 uniprotkb:Q80TP3 intact:EBI-4422044|uniprotkb:E9Q8I1|uniprotkb:Q3U513|uniprotkb:Q61027|uniprotkb:Q91YT5|uniprotkb:Q9QXD9|uniprotkb:Q9R177 intact:EBI-2553642|uniprotkb:Q810V6|uniprotkb:Q698K9|uniprotkb:Q9CXE9|uniprotkb:Q6PFQ9|uniprotkb:Q80VL4|uniprotkb:Q6PEQ8 psi-mi:rorg_mouse(display_long)|uniprotkb:Rorc(gene name)|psi-mi:Rorc(display_short)|uniprotkb:Nr1f3(gene name synonym)|uniprotkb:Rorg(gene name synonym)|uniprotkb:Thor(gene name synonym)|uniprotkb:Nuclear receptor RZR-gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 3(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-gamma(gene name synonym)|uniprotkb:Thymus orphan receptor(gene name synonym)|uniprotkb:RAR-related orphan receptor C(gene name synonym) psi-mi:ubr5_mouse(display_long)|uniprotkb:Ubr5(gene name)|psi-mi:Ubr5(display_short)|uniprotkb:Edd(gene name synonym)|uniprotkb:Edd1(gene name synonym)|uniprotkb:Kiaa0896(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Rutz et al. (2015) pubmed:25470037|doi:10.1038/nature13979|imex:IM-24397 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16131270|imex:IM-24397-3|dip:DIP-199026E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001280663.1|refseq:NP_035411.2|reactome:R-MMU-383280|dip:DIP-59439N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019218"(regulation of steroid metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036315"(cellular response to sterol)|go:"GO:0042093"(T-helper cell differentiation)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045586"(regulation of gamma-delta T cell differentiation)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048535"(lymph node development)|go:"GO:0048537"(mucosa-associated lymphoid tissue development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0098531"(ligand-activated transcription factor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003079(Nuclear receptor ROR)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR044101 go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|go:"GO:0061630"(ubiquitin protein ligase activity)|refseq:NP_001074828.2|refseq:NP_001106192.1|dip:DIP-56890N|mint:Q80TP3 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/08 2017/08/10 rogid:UN/SJWwC1Jl05UgqUvGdYMPJLas10090 rogid:iUtn1CtWFtqWQV3UH06xJ5R5Ux010090 rigid:oGvTdBV/fEJnqpxJw3j72tnrYWY false flag tag:c-c - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3U2S4-1 uniprotkb:Q80TP3 intact:EBI-16131219|ensembl:ENSMUSP00000033494 intact:EBI-2553642|uniprotkb:Q810V6|uniprotkb:Q698K9|uniprotkb:Q9CXE9|uniprotkb:Q6PFQ9|uniprotkb:Q80VL4|uniprotkb:Q6PEQ8 psi-mi:q3u2s4-1(display_long)|uniprotkb:Otud5(gene name)|psi-mi:Otud5(display_short)|uniprotkb:DXImx46e(gene name synonym)|uniprotkb:Sfc7(gene name synonym)|uniprotkb:Deubiquitinating enzyme A(gene name synonym) psi-mi:ubr5_mouse(display_long)|uniprotkb:Ubr5(gene name)|psi-mi:Ubr5(display_short)|uniprotkb:Edd(gene name synonym)|uniprotkb:Edd1(gene name synonym)|uniprotkb:Kiaa0896(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Rutz et al. (2015) pubmed:25470037|doi:10.1038/nature13979|imex:IM-24397 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16131248|imex:IM-24397-2|dip:DIP-199023E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031154(gene)|ensembl:ENSMUST00000033494(transcript)|intact:EBI-11021342(isoform-parent) go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|go:"GO:0061630"(ubiquitin protein ligase activity)|refseq:NP_001074828.2|refseq:NP_001106192.1|dip:DIP-56890N|mint:Q80TP3 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/08 2017/08/10 rogid:u8wgRhTTWzY37qh+nvsaG3LyrKw10090 rogid:iUtn1CtWFtqWQV3UH06xJ5R5Ux010090 rigid:MqOjf+xqoQ4ZEhAnh7D9lluKjUI false flag tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q3U2S4-1 uniprotkb:A2AN08 intact:EBI-16131219|ensembl:ENSMUSP00000033494 intact:EBI-4285947|uniprotkb:A2AN07|uniprotkb:A2AN09|uniprotkb:A2AN10|uniprotkb:A2AN11|uniprotkb:Q52KI4|uniprotkb:Q6PB49|uniprotkb:Q6PFC7|uniprotkb:Q80Y11|uniprotkb:Q8BGB9|uniprotkb:Q8C3E8|uniprotkb:Q8C4W5|uniprotkb:Q8C8X7|uniprotkb:Q8CGE0|uniprotkb:Q8CHF3|ensembl:ENSMUSP00000095433 psi-mi:q3u2s4-1(display_long)|uniprotkb:Otud5(gene name)|psi-mi:Otud5(display_short)|uniprotkb:DXImx46e(gene name synonym)|uniprotkb:Sfc7(gene name synonym)|uniprotkb:Deubiquitinating enzyme A(gene name synonym) psi-mi:ubr4_mouse(display_long)|uniprotkb:Kiaa0462(gene name synonym)|uniprotkb:Zubr1(gene name synonym)|uniprotkb:N-recognin-4(gene name synonym)|uniprotkb:Ubr4(gene name)|psi-mi:Ubr4(display_short)|uniprotkb:Zinc finger UBR1-type protein 1(gene name synonym)|uniprotkb:p600(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Rutz et al. (2015) pubmed:25470037|doi:10.1038/nature13979|imex:IM-24397 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16131248|imex:IM-24397-2|dip:DIP-199023E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031154(gene)|ensembl:ENSMUST00000033494(transcript)|intact:EBI-11021342(isoform-parent) refseq:NP_001153791.1|dip:DIP-61499N|ensembl:ENSMUSG00000066036(gene)|ensembl:ENSMUST00000097822(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025704|interpro:IPR036322|mint:A2AN08|reactome:R-MMU-6798695|reactome:R-MMU-983168|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/08 2017/08/10 rogid:u8wgRhTTWzY37qh+nvsaG3LyrKw10090 rogid:dTpQoZkH0+rwfrguOvzwrbPh0+Y10090 rigid:MqOjf+xqoQ4ZEhAnh7D9lluKjUI false flag tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q80TP3 uniprotkb:Q3U2S4-1 intact:EBI-2553642|uniprotkb:Q810V6|uniprotkb:Q698K9|uniprotkb:Q9CXE9|uniprotkb:Q6PFQ9|uniprotkb:Q80VL4|uniprotkb:Q6PEQ8 intact:EBI-16131219|ensembl:ENSMUSP00000033494 psi-mi:ubr5_mouse(display_long)|uniprotkb:Ubr5(gene name)|psi-mi:Ubr5(display_short)|uniprotkb:Edd(gene name synonym)|uniprotkb:Edd1(gene name synonym)|uniprotkb:Kiaa0896(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym) psi-mi:q3u2s4-1(display_long)|uniprotkb:Otud5(gene name)|psi-mi:Otud5(display_short)|uniprotkb:DXImx46e(gene name synonym)|uniprotkb:Sfc7(gene name synonym)|uniprotkb:Deubiquitinating enzyme A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Rutz et al. (2015) pubmed:25470037|doi:10.1038/nature13979|imex:IM-24397 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16131289|imex:IM-24397-4|dip:DIP-199024E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|go:"GO:0061630"(ubiquitin protein ligase activity)|refseq:NP_001074828.2|refseq:NP_001106192.1|dip:DIP-56890N|mint:Q80TP3 ensembl:ENSMUSG00000031154(gene)|ensembl:ENSMUST00000033494(transcript)|intact:EBI-11021342(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/08 2017/08/10 rogid:iUtn1CtWFtqWQV3UH06xJ5R5Ux010090 rogid:u8wgRhTTWzY37qh+nvsaG3LyrKw10090 rigid:/9w0FAnf7dnVyUvBHC/XLSN8D8A false - flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)