#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P49753-1 uniprotkb:Q9NZ94-2 intact:EBI-16423051 intact:EBI-16423037 psi-mi:p49753-1(display_long)|uniprotkb:ACOT2(gene name)|psi-mi:ACOT2(display_short)|uniprotkb:PTE2(gene name synonym)|uniprotkb:PTE2A(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423036|imex:IM-26157-221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P49753(isoform-parent) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:3a++2vHE7Zr553F/LJ68pxvJ/289606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:RjGVqSih3ZmVOe9XVMZzbsUGuMo false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P05187 uniprotkb:Q9NZ94-2 intact:EBI-1211484|uniprotkb:P05188|uniprotkb:P06861|uniprotkb:Q53S78|uniprotkb:Q96DB7|ensembl:ENSP00000375881 intact:EBI-16423037 psi-mi:ppb1_human(display_long)|uniprotkb:ALPP(gene name)|psi-mi:ALPP(display_short)|uniprotkb:PLAP(gene name synonym)|uniprotkb:Placental alkaline phosphatase 1(gene name synonym)|uniprotkb:Alkaline phosphatase Regan isozyme(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423060|imex:IM-26157-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001623.3|ensembl:ENSG00000163283(gene)|ensembl:ENST00000392027(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR001952(Alkaline phosphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR018299|mint:P05187|rcsb pdb:1EW2|rcsb pdb:1ZEB|rcsb pdb:1ZED|rcsb pdb:1ZEF|rcsb pdb:2GLQ|rcsb pdb:3MK0|rcsb pdb:3MK1|rcsb pdb:3MK2|reactome:R-HSA-6811438 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:JtfGSKMzJL3vP08X7lDS117PYbY9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:YZiXETdY0dFfkd+9KgmuZTJsA2Q false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O94973-2 uniprotkb:Q9NZ94-2 intact:EBI-10981066|ensembl:ENSP00000327694 intact:EBI-16423037 psi-mi:o94973-2(display_long)|uniprotkb:AP2A2(gene name)|psi-mi:AP2A2(display_short)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:ADTAB(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:CLAPA2(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:HIP9(gene name synonym)|uniprotkb:HYPJ(gene name synonym)|uniprotkb:Huntingtin yeast partner J(gene name synonym)|uniprotkb:Huntingtin-interacting protein 9(gene name synonym)|uniprotkb:Huntingtin-interacting protein J(gene name synonym)|uniprotkb:KIAA0899(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423068|imex:IM-26157-181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642835(isoform-parent)|uniprotkb:O94973-2(isoform-parent)|ensembl:ENSG00000183020(gene)|ensembl:ENST00000332231(transcript) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - isoform-comment:No experimental confirmation available. - figure legend:Table 1-3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:bphgc5OtLeh97dypM1kuRa9VDGM9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:Ni8Qno51NBRh0rdr5jJxT/gR3Qs false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P18848 uniprotkb:Q9NZ94-2 intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3 intact:EBI-16423037 psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423074|imex:IM-26157-183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists." - figure legend:Table 1-4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:2UolKWXxKFddysaOo70/U/1pI5k9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:quBzsIRsmeRms+Bej0tQnGfBpMY false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6ZSJ8-2 uniprotkb:Q9NZ94-2 intact:EBI-16423088 intact:EBI-16423037 psi-mi:q6zsj8-2(display_long)|uniprotkb:C1orf122(gene name)|psi-mi:C1orf122(display_short) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423082|imex:IM-26157-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZSJ8(isoform-parent) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:jjGNGUUDS3QEO6VYxB4LcQnLtdI9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:0bWjWpLuy2/m1iMFvrTFXU8d+r0 false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P02745 uniprotkb:Q9NZ94-2 intact:EBI-1220209|uniprotkb:Q5T963|uniprotkb:B2R4X2|ensembl:ENSP00000363773|ensembl:ENSP00000385564 intact:EBI-16423037 psi-mi:c1qa_human(display_long)|uniprotkb:C1QA(gene name)|psi-mi:C1QA(display_short) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423094|imex:IM-26157-223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057075.1|refseq:NP_001334394.1|refseq:NP_001334395.1|ensembl:ENSG00000173372(gene)|ensembl:ENST00000374642(transcript)|ensembl:ENST00000402322(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005602"(complement component C1 complex)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007568"(aging)|go:"GO:0010039"(response to iron ion)|go:"GO:0016322"(neuron remodeling)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0048143"(astrocyte activation)|go:"GO:0050808"(synapse organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098794"(postsynapse)|go:"GO:0098883"(synapse pruning)|go:"GO:0150062"(complement-mediated synapse pruning)|go:"GO:0150064"(vertebrate eye-specific patterning)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR037572|rcsb pdb:1PK6|rcsb pdb:2JG8|rcsb pdb:2JG9|rcsb pdb:2WNU|rcsb pdb:2WNV|rcsb pdb:5HKJ|rcsb pdb:5HZF|rcsb pdb:6FCZ|rcsb pdb:6Z6V|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-977606 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:JOnVJ11QPTmKEEGIr3BAlb2j6+s9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:JxMx0JXTKY6a3DnbsevcWy5FYfk false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N163-1 uniprotkb:Q9NZ94-2 intact:EBI-1021318|ensembl:ENSP00000310670|ensembl:ENSP00000373930 intact:EBI-16423037 psi-mi:q8n163-1(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423179|imex:IM-26157-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-355410(q8n163_human)|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:U3SK1q/WSCZR+uGbN6LGZxGVPgc false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:P0DN86-1 intact:EBI-16423037 intact:EBI-16423210 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:p0dn86-1(display_long)|uniprotkb:CGB3(gene name)|psi-mi:CGB3(display_short)|uniprotkb:CGB(gene name synonym)|uniprotkb:CGB5(gene name)|psi-mi:CGB5(display_short)|uniprotkb:CGB8(gene name)|psi-mi:CGB8(display_short) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423185|imex:IM-26157-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:P0DN86(isoform-parent) - - - figure legend:Table 1-8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:Fg4f/QYLQ+ZjWmJ1xx/ZNXwdvi89606 rigid:wdHiqka5keQdg5xCbB8DSQ9k4zo false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:P07339 intact:EBI-16423037 intact:EBI-2115097|uniprotkb:Q6IB57|ensembl:ENSP00000236671 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:catd_human(display_long)|uniprotkb:CTSD(gene name)|psi-mi:CTSD(display_short)|uniprotkb:CPSD(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423192|imex:IM-26157-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_001900.1|dip:DIP-43906N|ensembl:ENSG00000117984(gene)|ensembl:ENST00000236671(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070001"(aspartic-type peptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033144|mint:P07339|rcsb pdb:1LYA|rcsb pdb:1LYB|rcsb pdb:1LYW|rcsb pdb:4OBZ|rcsb pdb:4OC6|rcsb pdb:4OD9|reactome:R-HSA-1442490|reactome:R-HSA-2022377|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-9018519 - - - figure legend:Table 1-9|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:M1qLQBlL2DSCZiAwIPee9Vza3dU9606 rigid:JXaFcfZ0thzbqEfW6JJ8WoJvasg false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:P05108-1 intact:EBI-16423037 intact:EBI-16423235 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:p05108-1(display_long)|uniprotkb:CYP11A1(gene name)|psi-mi:CYP11A1(display_short)|uniprotkb:CYP11A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423198|imex:IM-26157-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:P05108(isoform-parent) - - - figure legend:Table 1-10|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:I/jdJNWgdU7vLkY+5PwcsKUnBNI9606 rigid:PN3EeV9/GpEnjOB7QksbsM9E+Nk false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q9H4A9 intact:EBI-16423037 intact:EBI-2871328|uniprotkb:Q6UX92|uniprotkb:Q8TC95|uniprotkb:B2RCF8|uniprotkb:A0A024R6Y5|uniprotkb:B3KS59|uniprotkb:I3L248|ensembl:ENSP00000377430|ensembl:ENSP00000458977 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:dpep2_human(display_long)|uniprotkb:DPEP2(gene name)|psi-mi:DPEP2(display_short)|uniprotkb:UNQ284/PRO323(orf name) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423204|imex:IM-26157-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_071750.1|ensembl:ENSG00000167261(gene)|ensembl:ENST00000393847(transcript)|ensembl:ENST00000572888(transcript)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006691"(leukotriene metabolic process)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0070573"(metallodipeptidase activity)|interpro:IPR000180(Peptidase M19, renal dipeptidase, active site)|interpro:IPR008257(Peptidase M19, renal dipeptidase)|interpro:IPR028531|interpro:IPR032466|reactome:R-HSA-2142691|reactome:R-HSA-5423646|reactome:R-HSA-9664535 - - - figure legend:Table 1-11|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2018/04/06 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:soBoETD/fTJQuFLrzBydim41He89606 rigid:YCm/2EKIhwKhPMsosUZmkIVskdA false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q9BY08-1 intact:EBI-16423037 intact:EBI-16423266 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q9by08-1(display_long)|uniprotkb:EBPL(gene name)|psi-mi:EBPL(display_short)|uniprotkb:EBRP(gene name synonym)|uniprotkb:ERP(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423242|imex:IM-26157-225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q9BY08(isoform-parent) - - - figure legend:Table 1-12|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:ZloiP+PR+M6chD2wm/bc3bzItKU9606 rigid:TX4Tca70f2USNbrZDmezjPie30Q false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:P68104 intact:EBI-16423037 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423248|imex:IM-26157-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table 1-13|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2020/08/15 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:2/pm0uiFKksVGTCswuMt30+c+T4 false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:O43281-1 intact:EBI-16423037 intact:EBI-16423283|ensembl:ENSP00000216733 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:o43281-1(display_long)|uniprotkb:Cas scaffolding protein family member 3(gene name synonym)|uniprotkb:EFS(gene name)|psi-mi:EFS(display_short)|uniprotkb:CASS3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423254|imex:IM-26157-227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:O43281(isoform-parent)|ensembl:ENSG00000100842(gene)|ensembl:ENST00000216733(transcript)|intact:EBI-718488(isoform-parent) - - - figure legend:Table 1-14|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:7aO8sdSXU6RqHKK6NnxYRwcDet09606 rigid:jkhVNNTAYBHIkVP0Ye78TGxRGAU false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:O15287 intact:EBI-16423037 intact:EBI-81610|ensembl:ENSP00000367910 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:fancg_human(display_long)|uniprotkb:FANCG(gene name)|psi-mi:FANCG(display_short)|uniprotkb:XRCC9(gene name synonym)|uniprotkb:DNA repair protein XRCC9(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423260|imex:IM-26157-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) ensembl:ENSG00000221829(gene)|refseq:NP_004620.1|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007286"(spermatid development)|go:"GO:0009314"(response to radiation)|ensembl:ENST00000378643(transcript)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039684|mint:O15287|rcsb pdb:7KZP|rcsb pdb:7KZQ|go:"GO:0001541"(ovarian follicle development)|rcsb pdb:7KZR|go:"GO:0003684"(damaged DNA binding)|rcsb pdb:7KZS|go:"GO:0005654"(nucleoplasm)|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|go:"GO:0005730"(nucleolus) - - - figure legend:Table 1-15|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:jVGeic2vn/qrZgro3IKXWhNteHo9606 rigid:1XibzCtRG4V0prGbywAchlBpYE4 false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:P23142 intact:EBI-16423037 intact:EBI-726652|uniprotkb:P23143|uniprotkb:P23144|uniprotkb:P37888|uniprotkb:Q5TIC4|uniprotkb:Q8TBH8|uniprotkb:Q9HBQ5|uniprotkb:Q9UC21|uniprotkb:Q9UGR4|uniprotkb:Q9UH41|uniprotkb:B0QY42|intact:EBI-2562209|ensembl:ENSP00000331544|uniprotkb:B1AHL4 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:fbln1_human(display_long)|uniprotkb:FBLN1(gene name)|psi-mi:FBLN1(display_short)|uniprotkb:PP213(orf name) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423290|imex:IM-26157-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_001987.2|refseq:NP_006476.2|refseq:NP_006477.2|refseq:NP_006478.2|ensembl:ENSG00000077942(gene)|ensembl:ENST00000327858(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007566"(embryo implantation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070051"(fibrinogen binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0071953"(elastic fiber)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904188"(negative regulation of transformation of host cell by virus)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000647"(negative regulation of stem cell proliferation)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR017048(Fibulin-1)|interpro:IPR018097|interpro:IPR026823|mint:P23142|reactome:R-HSA-2129379|go:"GO:0005201"(extracellular matrix structural constituent) - - - figure legend:Table 1-16|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:a47ZJLXWeghGIY9xJTQI7VujuMk9606 rigid:FUU2M2ME62UZ7QHqhnm/MQl+0b4 false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q9Y613 intact:EBI-16423037 intact:EBI-348433|ensembl:ENSP00000258201|uniprotkb:Q59F76|uniprotkb:Q6Y1F2|uniprotkb:Q76MS8|uniprotkb:Q8N521 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:fhod1_human(display_long)|uniprotkb:FHOD1(gene name)|psi-mi:FHOD1(display_short)|uniprotkb:FHOS(gene name synonym)|uniprotkb:FHOS1(gene name synonym)|uniprotkb:Formin homolog overexpressed in spleen 1(gene name synonym)|uniprotkb:Formin homology 2 domain-containing protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423296|imex:IM-26157-121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_037373.2|ensembl:ENSG00000135723(gene)|ensembl:ENST00000258201(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007097"(nuclear migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032059"(bleb)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051015"(actin filament binding)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0051660"(establishment of centrosome localization)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027647|interpro:IPR041387|interpro:IPR042201|rcsb pdb:3DAD|rcsb pdb:6XF1|rcsb pdb:6XF2|mint:Q9Y613|dip:DIP-31134N - - - figure legend:Table 1-17|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:8zGurHJ5FL9gvqZazyRAHElMAdI9606 rigid:6pp2K75HhvfJKKq9IXsBlZ41RNQ false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:P62942 intact:EBI-16423037 intact:EBI-1027571|uniprotkb:P20071|uniprotkb:Q4VC47|uniprotkb:Q6FGD9|uniprotkb:Q6LEU3|uniprotkb:Q9H103|uniprotkb:Q9H566|uniprotkb:D3DVW6|ensembl:ENSP00000371138|ensembl:ENSP00000371143|ensembl:ENSP00000383003|ensembl:ENSP00000503033|ensembl:ENSP00000503152 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:fkb1a_human(display_long)|uniprotkb:FKBP1A(gene name)|psi-mi:FKBP1A(display_short)|uniprotkb:FKBP1(gene name synonym)|uniprotkb:FKBP12(gene name synonym)|uniprotkb:FK506-binding protein 1A(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Immunophilin FKBP12(gene name synonym)|uniprotkb:12 kDa FK506-binding protein(gene name synonym)|uniprotkb:Calstabin-1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423302|imex:IM-26157-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) ensembl:ENSG00000088832(gene)|ensembl:ENST00000381719(transcript)|ensembl:ENST00000381724(transcript)|ensembl:ENST00000400137(transcript)|ensembl:ENST00000677335(transcript)|ensembl:ENST00000678408(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005527"(macrolide binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0014802"(terminal cisterna)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030018"(Z disc)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031312"(extrinsic component of organelle membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0042026"(protein refolding)|go:"GO:0042110"(T cell activation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0048185"(activin binding)|go:"GO:0050776"(regulation of immune response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1A7X|rcsb pdb:1B6C|rcsb pdb:1BKF|rcsb pdb:1BL4|rcsb pdb:1D6O|rcsb pdb:1D7H|rcsb pdb:1D7I|rcsb pdb:1D7J|rcsb pdb:1EYM|rcsb pdb:1F40|rcsb pdb:1FAP|rcsb pdb:1FKB|rcsb pdb:1FKD|rcsb pdb:1FKF|rcsb pdb:1FKG|rcsb pdb:1FKH|rcsb pdb:1FKI|rcsb pdb:2DG4|rcsb pdb:2DG9|rcsb pdb:2FAP|rcsb pdb:2FKE|rcsb pdb:2ND5|rcsb pdb:2PPN|rcsb pdb:2PPO|rcsb pdb:2PPP|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:1FKJ|rcsb pdb:3H9R|rcsb pdb:3MDY|rcsb pdb:4DH0|rcsb pdb:4FAP|rcsb pdb:1FKR|rcsb pdb:4IPX|rcsb pdb:4N19|rcsb pdb:4ODP|rcsb pdb:4ODQ|rcsb pdb:4ODR|rcsb pdb:5I7P|rcsb pdb:5I7Q|rcsb pdb:6I1S|rcsb pdb:1FKS|rcsb pdb:6M4U|rcsb pdb:6OQA|rcsb pdb:6VCU|rcsb pdb:6YF0|rcsb pdb:6YF1|rcsb pdb:6YF2|rcsb pdb:6YF3|reactome:R-HSA-166208|rcsb pdb:1FKT|reactome:R-HSA-2025928|reactome:R-HSA-2173789|reactome:R-HSA-2173791|reactome:R-HSA-3656535|rcsb pdb:1J4H|rcsb pdb:1J4I|reactome:R-HSA-9679191|rcsb pdb:1J4R|rcsb pdb:1NSG|rcsb pdb:1QPF|rcsb pdb:1QPL|rcsb pdb:2DG3|refseq:NP_000792.1|refseq:NP_463460.1|dip:DIP-29710N - - - figure legend:Table 1-18|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:3eikHNIIVs8AFM7PYVWurI/9KUY9606 rigid:OFNQhALy7xkoBJ/3pJYpkVSFdqQ false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P21333-2 uniprotkb:Q9NZ94-2 intact:EBI-9641086|ensembl:ENSP00000353467 intact:EBI-16423037 psi-mi:p21333-2(display_long)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423308|imex:IM-26157-185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-350432(isoform-parent)|ensembl:ENSG00000196924(gene)|ensembl:ENST00000360319(transcript)|uniprotkb:P21333-2(isoform-parent) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - isoform-comment:No experimental confirmation available. - figure legend:Table 1-19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:r3XEZc6gmq37vSWBuSgyVvIf7Sc9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:VY2nzgTSoqwBepCTkhkeAjgogZc false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q99988 intact:EBI-16423037 intact:EBI-2116863|uniprotkb:O14629|uniprotkb:P78360|uniprotkb:Q9NRT0|uniprotkb:Q9BWA0|ensembl:ENSP00000252809 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:gdf15_human(display_long)|uniprotkb:GDF15(gene name)|psi-mi:GDF15(display_short)|uniprotkb:MIC1(gene name synonym)|uniprotkb:PDF(gene name synonym)|uniprotkb:PLAB(gene name synonym)|uniprotkb:PTGFB(gene name synonym)|uniprotkb:Placental bone morphogenetic protein(gene name synonym)|uniprotkb:Placental TGF-beta(gene name synonym)|uniprotkb:Macrophage inhibitory cytokine 1(gene name synonym)|uniprotkb:Prostate differentiation factor(gene name synonym)|uniprotkb:NSAID-activated gene 1 protein(gene name synonym)|uniprotkb:NSAID-regulated gene 1 protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423314|imex:IM-26157-141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_004855.2|ensembl:ENSG00000130513(gene)|ensembl:ENST00000252809(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002023"(reduction of food intake in response to dietary excess)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008083"(growth factor activity)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035860"(glial cell-derived neurotrophic factor receptor signaling pathway)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060400"(negative regulation of growth hormone receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070700"(BMP receptor binding)|go:"GO:1901741"(positive regulation of myoblast fusion)|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR029034|rcsb pdb:5VT2|rcsb pdb:5VZ3|rcsb pdb:5VZ4|rcsb pdb:6Q2J - - - figure legend:Table 1-20|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:W0oAT+oBcB2pzGNCol0EAfF7CqA9606 rigid:XxxMHT+d4fkbTnZ9osCBJEOF1hg false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q16774-2 intact:EBI-16423037 intact:EBI-16423350 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q16774-2(display_long)|uniprotkb:GUK1(gene name)|psi-mi:GUK1(display_short)|uniprotkb:GMK(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423320|imex:IM-26157-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q16774(isoform-parent) - - - figure legend:Table 1-21|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:JTehFfJfLTl3HHYVvw26cEpIOCw9606 rigid:Rl9WliYO6MFwwUBo3GMiI1tlRK0 false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q8IV36-1 intact:EBI-16423037 intact:EBI-16423357 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q8iv36-1(display_long)|uniprotkb:HID1(gene name)|psi-mi:HID1(display_short)|uniprotkb:C17orf28(gene name synonym)|uniprotkb:DMC1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423326|imex:IM-26157-123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q8IV36(isoform-parent) - - - figure legend:Table 1-22|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:JbuUtArSvjy+ToF/IuqCDBvZb/Q9606 rigid:eK9slumxiUcPpxZt4PAjgs+kw7Q false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q8IWB1 intact:EBI-16423037 intact:EBI-2556412|uniprotkb:Q5JU17|uniprotkb:Q96MS8|uniprotkb:Q9C0A9|uniprotkb:D3DRA5|ensembl:ENSP00000278071|ensembl:ENSP00000337178|ensembl:ENSP00000350915|ensembl:ENSP00000497746 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:ipri_human(display_long)|uniprotkb:DANGER(gene name synonym)|uniprotkb:KIAA1754(gene name synonym)|uniprotkb:Protein DANGER(gene name synonym)|uniprotkb:ITPRIP(gene name)|psi-mi:ITPRIP(display_short) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423332|imex:IM-26157-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_203755.1|ensembl:ENSG00000148841(gene)|ensembl:ENST00000278071(transcript)|ensembl:ENST00000337478(transcript)|ensembl:ENST00000358187(transcript)|ensembl:ENST00000647721(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR024797|interpro:IPR024810|interpro:IPR026250|refseq:NP_001258941.1|refseq:NP_001258942.1 - - - figure legend:Table 1-23|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:wTUAsA+dqm1wkrs9z4E7a4PdcLk9606 rigid:Qg7lZWMJ0Ogfk/wXcJx6Z1cb0W4 false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:P09382 intact:EBI-16423037 intact:EBI-1048875|uniprotkb:B2R5E8|uniprotkb:Q9UDK5|ensembl:ENSP00000215909 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:leg1_human(display_long)|uniprotkb:Lectin galactoside-binding soluble 1(gene name synonym)|uniprotkb:Beta-galactoside-binding lectin L-14-I(gene name synonym)|uniprotkb:S-Lac lectin 1(gene name synonym)|uniprotkb:Galaptin(gene name synonym)|uniprotkb:14 kDa lectin(gene name synonym)|uniprotkb:HPL(gene name synonym)|uniprotkb:HBL(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM12(gene name synonym)|uniprotkb:LGALS1(gene name)|psi-mi:LGALS1(display_short)|uniprotkb:Lactose-binding lectin 1(gene name synonym)|uniprotkb:14 kDa laminin-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423338|imex:IM-26157-187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_002296.1|ensembl:ENST00000215909(transcript)|go:"GO:0002317"(plasma cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030395"(lactose binding)|ensembl:ENSG00000100097(gene)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P09382|rcsb pdb:1GZW|rcsb pdb:1W6M|rcsb pdb:1W6N|rcsb pdb:1W6O|rcsb pdb:1W6P|rcsb pdb:1W6Q|rcsb pdb:2KM2|rcsb pdb:2ZKN|rcsb pdb:3OY8|rcsb pdb:3OYW|rcsb pdb:3T2T|rcsb pdb:3W58|rcsb pdb:3W59|rcsb pdb:4Q1P|go:"GO:0031295"(T cell costimulation)|go:"GO:0034120"(positive regulation of erythrocyte aggregation)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043236"(laminin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0048678"(response to axon injury)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4Q1R|rcsb pdb:4Q26|rcsb pdb:4Q27|rcsb pdb:4Q2F|rcsb pdb:4XBL|rcsb pdb:4Y1U|rcsb pdb:4Y1V|rcsb pdb:4Y1X|rcsb pdb:4Y1Y|rcsb pdb:4Y1Z|rcsb pdb:4Y20|rcsb pdb:4Y22|rcsb pdb:4Y24|rcsb pdb:5MWT|rcsb pdb:5MWX|rcsb pdb:6B94|rcsb pdb:6F83|rcsb pdb:6M5Y|reactome:R-HSA-381426|reactome:R-HSA-8957275|dip:DIP-46153N - - - figure legend:Table 1-24|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:Sov3RfY2NOjdjuvdFlEd/vaNTMY9606 rigid:vUlo+Od67P5lskp6z0Ouh/DyAFU false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q9NTJ4-1 intact:EBI-16423037 intact:EBI-16423365 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q9ntj4-1(display_long)|uniprotkb:MAN2C1(gene name)|psi-mi:MAN2C1(display_short)|uniprotkb:MANA(gene name synonym)|uniprotkb:MANA1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423344|imex:IM-26157-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q9NTJ4(isoform-parent) - - - figure legend:Table 1-25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:czl0+oYTt//dDjYu1Q0zf5BPYss9606 rigid:g8x6Lel5Gv2LeHCAO9TiPvrLAGY false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q66K74-1 intact:EBI-16423037 intact:EBI-16423404 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q66k74-1(display_long)|uniprotkb:MAP1S(gene name)|psi-mi:MAP1S(display_short)|uniprotkb:BPY2IP1(gene name synonym)|uniprotkb:C19orf5(gene name synonym)|uniprotkb:MAP8(gene name synonym)|uniprotkb:VCY2IP1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423374|imex:IM-26157-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q66K74(isoform-parent) - - - figure legend:Table 1-26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:f+UnRFHFEFKp2fTRCHt4/HXtnFQ9606 rigid:i8w3CEtfTEFQeeZmbt8JQmGqrbk false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q9BRT3 intact:EBI-16423037 intact:EBI-6137472|ensembl:ENSP00000377778 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:mien1_human(display_long)|uniprotkb:MIEN1(gene name)|psi-mi:MIEN1(display_short)|uniprotkb:C17orf37(gene name synonym)|uniprotkb:RDX12(gene name synonym)|uniprotkb:XTP4(gene name synonym)|uniprotkb:HBV X-transactivated gene 4 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 4(gene name synonym)|uniprotkb:Protein C35(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423380|imex:IM-26157-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_115715.3|refseq:NP_001317135.1|ensembl:ENSG00000141741(gene)|ensembl:ENST00000394231(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0010269"(response to selenium ion)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051491"(positive regulation of filopodium assembly)|interpro:IPR011893(SelT/selW/selH selenoprotein)|interpro:IPR036249|rcsb pdb:2LJK - - - figure legend:Table 1-27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:ViTKcje+j8lSpoS24M+Mn05tm0U9606 rigid:KRDLiMiawKDcTYw7x/4r5zrSrEk false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P00403 uniprotkb:Q9NZ94-2 intact:EBI-2105756|uniprotkb:Q37526|ensembl:ENSP00000354876 intact:EBI-16423037 psi-mi:cox2_human(display_long)|uniprotkb:MT-CO2(gene name)|psi-mi:MT-CO2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:COXII(gene name synonym)|uniprotkb:MTCO2(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:COX2(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423386|imex:IM-26157-125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_003024029.1|ensembl:ENSG00000198712(gene)|ensembl:ENST00000361739(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00403|rcsb pdb:3VRJ|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:NyMmciQe53E935KEZahz8cGPjIM9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:kmmfWUMSdAkbx/RcLUzTmYGBr6Q false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q14934-3 intact:EBI-16423037 intact:EBI-16423423 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q14934-3(display_long)|uniprotkb:NFATC4(gene name)|psi-mi:NFATC4(display_short)|uniprotkb:NFAT3(gene name synonym)|uniprotkb:IA-IXi(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423392|imex:IM-26157-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q14934(isoform-parent) - - - figure legend:Table 1-29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:Ogk9Y8Gc5YcV4Y3QJArCE18YZ2A9606 rigid:Mb9FlAS3ESs3cwr3K3Yr8DPvo90 false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:O43847 intact:EBI-16423037 intact:EBI-2371631|uniprotkb:O15241|uniprotkb:O15242|uniprotkb:Q5VUL0|uniprotkb:Q96HB2|uniprotkb:Q9NU57|uniprotkb:A6NI41|ensembl:ENSP00000262679|intact:EBI-6137671 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:nrdc_human(display_long)|uniprotkb:NRDC(gene name)|psi-mi:NRDC(display_short)|uniprotkb:N-arginine dibasic convertase(gene name synonym)|uniprotkb:NRD1(gene name synonym)|uniprotkb:Nardilysin convertase(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423398|imex:IM-26157-189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_001095132.1|refseq:NP_001229290.1|refseq:NP_002516.2|ensembl:ENSG00000078618(gene)|ensembl:ENST00000352171(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0009986"(cell surface)|go:"GO:0046872"(metal ion binding)|go:"GO:0048408"(epidermal growth factor binding)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR032632|mint:O43847 - - - figure legend:Table 1-30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2018/10/11 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:zvZTk2Q799M8nsREOYmuYPF/x1U9606 rigid:j8ijqpbMJA1ZhncUWin3fILLi3U false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:P54368 intact:EBI-16423037 intact:EBI-948441|ensembl:ENSP00000473381|uniprotkb:O43382|uniprotkb:Q14989|uniprotkb:Q92595|uniprotkb:Q9UPL9 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:oaz1_human(display_long)|uniprotkb:OAZ1(gene name)|psi-mi:OAZ1(display_short)|uniprotkb:OAZ(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423432|imex:IM-26157-191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) ensembl:ENSG00000104904(gene)|ensembl:ENST00000602676(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008073"(ornithine decarboxylase inhibitor activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:1902268"(negative regulation of polyamine transmembrane transport)|interpro:IPR002993(Ornithine decarboxylase antizyme)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR029914|mint:P54368|rcsb pdb:4ZGY|rcsb pdb:4ZGZ|rcsb pdb:5BWA|reactome:R-HSA-350562|interpro:IPR038581|refseq:NP_004143.1 - - - figure legend:Table 1-31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:rrf1LoIm0F76PUQlVAva8tbH+w49606 rigid:s+gEhdYK/n7MgxYEx5cp1UuAYT8 false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q8NHA8 intact:EBI-16423037 intact:EBI-16423482 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:or1fc_human(display_long)|uniprotkb:Hs6M1-35P(gene name synonym)|uniprotkb:OR1F12(gene name)|psi-mi:OR1F12(display_short)|uniprotkb:OR1F12P(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423438|imex:IM-26157-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004984"(olfactory receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-381753|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR000725(Olfactory receptor) - - - figure legend:Table 1-32|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:ad4UlRZMXszO70AkdwoQXKh0Vr09606 rigid:u5oH7RUkKn8P24uUANZ9EMdv67s false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q9C010-1 intact:EBI-16423037 intact:EBI-16423508|ensembl:ENSP00000346227|ensembl:ENSP00000357433|ensembl:ENSP00000357437|ensembl:ENSP00000376280|ensembl:ENSP00000376281 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q9c010-1(display_long)|uniprotkb:PKIB(gene name)|psi-mi:PKIB(display_short)|uniprotkb:PRKACN2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423444|imex:IM-26157-143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q9C010(isoform-parent)|ensembl:ENSG00000135549(gene)|ensembl:ENST00000354275(transcript)|ensembl:ENST00000368448(transcript)|ensembl:ENST00000368452(transcript)|ensembl:ENST00000392490(transcript)|ensembl:ENST00000392491(transcript)|intact:EBI-3912499(isoform-parent) - - - figure legend:Table 1-33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:svORJ5YnQvam7CC8WDVHny0E+PE9606 rigid:FA1bo+XWvcwoyB8UX5KjHgQaLWQ false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q15147-4 intact:EBI-16423037 intact:EBI-16423529 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q15147-4(display_long)|uniprotkb:PLCB4(gene name)|psi-mi:PLCB4(display_short) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423450|imex:IM-26157-161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q15147(isoform-parent) - - - figure legend:Table 1-35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:UTeUq2LxYdyBB5nYWz2vFtDzbFw9606 rigid:Z+WcraQEecbmRjnlENpmPFojCyY false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q6P1J6-1 intact:EBI-16423037 intact:EBI-16423521|ensembl:ENSP00000330442 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q6p1j6-1(display_long)|uniprotkb:Phospholipase B/lipase(gene name synonym)|uniprotkb:PLB1(gene name)|psi-mi:PLB1(display_short)|uniprotkb:PLB(gene name synonym)|uniprotkb:Lysophospholipase(gene name synonym)|uniprotkb:Phospholipase A2(gene name synonym)|uniprotkb:Triacylglycerol lipase(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423515|imex:IM-26157-145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q6P1J6(isoform-parent)|ensembl:ENSG00000163803(gene)|ensembl:ENST00000327757(transcript)|intact:EBI-10757275(isoform-parent) - - - figure legend:Table 1-34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:HouhRFRQLWDFlTa/FgjKK5Pxnp49606 rigid:pXjcpDPq/wjM6LMBTafKJzr5rvo false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:P07602-3 intact:EBI-16423037 intact:EBI-16423568 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:p07602-3(display_long)|uniprotkb:Proactivator polypeptide(gene name synonym)|uniprotkb:PSAP(gene name)|psi-mi:PSAP(display_short)|uniprotkb:GLBA(gene name synonym)|uniprotkb:SAP1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423536|imex:IM-26157-147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:P07602(isoform-parent)|intact:EBI-716699(isoform-parent) - - - figure legend:Table 1-36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:W6Os8JS5CxY91pyescyMS1idBX89606 rigid:rUd1mLjQMj70XAYC0nGGEzq+BjU false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:P11464-4 intact:EBI-16423037 intact:EBI-16423576|ensembl:ENSP00000244296 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:p11464-4(display_long)|uniprotkb:PSG1(gene name)|psi-mi:PSG1(display_short)|uniprotkb:B1G1(gene name synonym)|uniprotkb:PSBG1(gene name synonym)|uniprotkb:PSGGA(gene name synonym)|uniprotkb:CD66 antigen-like family member F(gene name synonym)|uniprotkb:Fetal liver non-specific cross-reactive antigen 1/2(gene name synonym)|uniprotkb:PSG95(gene name synonym)|uniprotkb:Pregnancy-specific beta-1 glycoprotein C/D(gene name synonym)|uniprotkb:PSG-1d(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423542|imex:IM-26157-149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:P11464(isoform-parent)|ensembl:ENSG00000231924(gene)|ensembl:ENST00000244296(transcript)|intact:EBI-716740(isoform-parent) - - - figure legend:Table 1-37|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:H6tQwUo4u2VMd2HhJDO28kdJeVY9606 rigid:swiYHzMxaxHnw8oJR6a8f/wpXyY false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16557 uniprotkb:Q9NZ94-2 intact:EBI-7222484|intact:MINT-1186118|uniprotkb:Q9UPL4|uniprotkb:Q08265|uniprotkb:Q9UQ77|uniprotkb:Q9BRW2|ensembl:ENSP00000332215|ensembl:ENSP00000480223 intact:EBI-16423037 psi-mi:psg3_human(display_long)|uniprotkb:PSG3(gene name)|psi-mi:PSG3(display_short)|uniprotkb:Carcinoembryonic antigen SG5(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423548|imex:IM-26157-201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066296.2|ensembl:ENSG00000221826(gene)|ensembl:ENST00000327495(transcript)|ensembl:ENST00000614582(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0006952"(defense response)|go:"GO:0007565"(female pregnancy)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-202733|interpro:IPR003599(Immunoglobulin subtype) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - comment:mint|comment:homomint - figure legend:Table 1-38|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:gbRuqIlzzosHJl7gad++bJWwyHE9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:UsF+/JYUkzCKnY13Lf08M+9Kh2A false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q00888-1 intact:EBI-16423037 intact:EBI-16423587 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q00888-1(display_long)|uniprotkb:PSG4(gene name)|psi-mi:PSG4(display_short)|uniprotkb:CGM4(gene name synonym)|uniprotkb:PSG9(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423554|imex:IM-26157-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q00888(isoform-parent) - - - figure legend:Table 1-39|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:YYvGU3/+/SUy6jLARQnviakEe/s9606 rigid:VqXgCpoDttzd6OcsSznuiSuSxAA false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q15238 intact:EBI-16423037 intact:EBI-4314891|uniprotkb:Q15239|uniprotkb:Q96QJ1|uniprotkb:Q9UQ75|ensembl:ENSP00000344413|ensembl:ENSP00000382334|ensembl:ENSP00000386008 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:psg5_human(display_long)|uniprotkb:PSG5(gene name)|psi-mi:PSG5(display_short)|uniprotkb:Fetal liver non-specific cross-reactive antigen 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16423562|imex:IM-26157-203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_001123486.1|refseq:NP_002772.3|refseq:XP_016882492.1|ensembl:ENSG00000204941(gene)|ensembl:ENST00000342951(transcript)|ensembl:ENST00000366175(transcript)|ensembl:ENST00000407356(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007565"(female pregnancy)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-202733 - - - figure legend:Table 1-40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/04 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:O5maHM77+s2CWMD1oFv4jzy80G49606 rigid:qeGTc5H7loswlw0nYmgtZSwRMCk false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:Q9UQ72-1 intact:EBI-16423037 intact:EBI-16424294 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q9uq72-1(display_long)|uniprotkb:PSG11(gene name)|psi-mi:PSG11(display_short)|uniprotkb:PSG13(gene name synonym)|uniprotkb:PSG14(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424264|imex:IM-26157-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q9UQ72(isoform-parent) - - - figure legend:Table 1-41|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:5jzOv/gBiVrbHqNJnkBZSGxxcs89606 rigid:h/Bv8TF7YAhFjOL3TMNY8vaRBpY false sufficient binding region:711-828 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P47897-1 uniprotkb:Q9NZ94-2 intact:EBI-16424302|ensembl:ENSP00000307567 intact:EBI-16423037 psi-mi:p47897-1(display_long)|uniprotkb:QARS1(gene name)|psi-mi:QARS1(display_short)|uniprotkb:Glutaminyl-tRNA synthetase(gene name synonym)|uniprotkb:QARS(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424270|imex:IM-26157-229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000306125(transcript)|ensembl:ENSG00000172053(gene)|uniprotkb:P47897(isoform-parent)|intact:EBI-347462(isoform-parent) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-42|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:3Q8LR+aWJJue/ixtD3ZYDpC/D3o9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:NKUNtr7gB/Jx+t3i0+uzgq6sGY8 false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15274 uniprotkb:Q9NZ94-2 intact:EBI-739851|uniprotkb:Q53XW7|uniprotkb:Q96G22|uniprotkb:Q9BSG6|ensembl:ENSP00000378782|ensembl:ENSP00000404873 intact:EBI-16423037 psi-mi:nadc_human(display_long)|uniprotkb:QPRT(gene name)|psi-mi:QPRT(display_short)|uniprotkb:Quinolinate phosphoribosyltransferase [decarboxylating](gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424276|imex:IM-26157-231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055113.2|refseq:NP_001305178.1|refseq:NP_001305179.1|ensembl:ENSG00000103485(gene)|ensembl:ENST00000395384(transcript)|ensembl:ENST00000449759(transcript)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0034213"(quinolinate catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902494"(catalytic complex)|interpro:IPR002638(Quinolinate phosphoribosyl transferase)|interpro:IPR004393(Nicotinate-nucleotide pyrophosphorylase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR022412|interpro:IPR027277|interpro:IPR036068|interpro:IPR037128|rcsb pdb:2JBM|rcsb pdb:4KWV|rcsb pdb:4KWW|rcsb pdb:5AYX|rcsb pdb:5AYY|rcsb pdb:5AYZ|reactome:R-HSA-196807 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-43|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:ayjZsjJprp+eirEIN5VqDHmIzoA9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:GJqe71bl5y5Hl12MEa6Kc5lU69w false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96R06 uniprotkb:Q9NZ94-2 intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300 intact:EBI-16423037 psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424282|imex:IM-26157-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-44|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:dwbY4p8Dn/XrZSWpfxu1ML4n70Q false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43278-1 uniprotkb:Q9NZ94-2 intact:EBI-15822221|ensembl:ENSP00000342098 intact:EBI-16423037 psi-mi:o43278-1(display_long)|uniprotkb:UNQ223/PRO256(orf name)|uniprotkb:HAI-1B(isoform synonym)|uniprotkb:Hepatocyte growth factor activator inhibitor type 1(gene name synonym)|uniprotkb:SPINT1(gene name)|psi-mi:SPINT1(display_short)|uniprotkb:HAI1(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424288|imex:IM-26157-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166145(gene)|ensembl:ENST00000344051(transcript)|intact:EBI-953990(isoform-parent) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-45|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:feHnyLQq6rOSG2IW9dCGVBkcurg9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:HDNI7DDe/qP9722F0vM08JQlaog false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P51571 uniprotkb:Q9NZ94-2 intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104 intact:EBI-16423037 psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424308|imex:IM-26157-127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-46|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:CX1uMBTW01+xxtQvf+HoBexguSA false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P45378-2 uniprotkb:Q9NZ94-2 intact:EBI-16424344 intact:EBI-16423037 psi-mi:p45378-2(display_long)|uniprotkb:TNNT3(gene name)|psi-mi:TNNT3(display_short)|uniprotkb:Tnt3(isoform synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424314|imex:IM-26157-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P45378(isoform-parent)|uniprotkb:P45378-2(isoform-parent) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-47|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:DqSRBaNIOwW6tqqsSuslL+L5PhA9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:DB89Lgq/jOMdMJ4PL4sk2EBec9o false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UPN9-1 uniprotkb:Q9NZ94-2 intact:EBI-16424351 intact:EBI-16423037 psi-mi:q9upn9-1(display_long)|uniprotkb:TRIM33(gene name)|psi-mi:TRIM33(display_short)|uniprotkb:KIAA1113(gene name synonym)|uniprotkb:RFG7(gene name synonym)|uniprotkb:TIF1G(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424320|imex:IM-26157-129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9UPN9(isoform-parent) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-48|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:DB02UIWcpeneONPdG17AS08/9/A9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:JnHMW2e4rXY4wmm+p54tZ4PGAe0 false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H3M7-1 uniprotkb:Q9NZ94-2 intact:EBI-11666025|ensembl:ENSP00000462521 intact:EBI-16423037 psi-mi:q9h3m7-1(display_long)|uniprotkb:TXNIP(gene name)|psi-mi:TXNIP(display_short)|uniprotkb:VDUP1(gene name synonym)|uniprotkb:Thioredoxin-binding protein 2(gene name synonym)|uniprotkb:Vitamin D3 up-regulated protein 1(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424326|imex:IM-26157-193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1369170(isoform-parent)|ensembl:ENSG00000265972(gene)|ensembl:ENST00000582401(transcript) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-49|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:jJMKfl1/92UPMTXBLCdu6NcYbjQ9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:ZxGVT49cBc+RI4vB3lAJKYmHkYU false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BZV1-1 uniprotkb:Q9NZ94-2 intact:EBI-16424361 intact:EBI-16423037 psi-mi:q9bzv1-1(display_long)|uniprotkb:UBXN6(gene name)|psi-mi:UBXN6(display_short)|uniprotkb:UBXD1(gene name synonym)|uniprotkb:UBXDC2(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424332|imex:IM-26157-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9BZV1(isoform-parent) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-50|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:bdhN1ftwK7aQRHUgkBTclJ/z3SQ9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:vuCyYpxYyxq18Jzy1QsKdUhFiyo false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P31930 uniprotkb:Q9NZ94-2 intact:EBI-1052596|uniprotkb:Q96DD2|uniprotkb:B2R7R8|ensembl:ENSP00000203407 intact:EBI-16423037 psi-mi:qcr1_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 1(gene name synonym)|uniprotkb:Complex III subunit 1(gene name synonym)|uniprotkb:UQCRC1(gene name)|psi-mi:UQCRC1(display_short)|uniprotkb:Core protein I(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424338|imex:IM-26157-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003356.2|ensembl:ENSG00000010256(gene)|ensembl:ENST00000203407(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0014823"(response to activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P31930|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-51|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:7Yrm6OhOmgfHF5mAX3hT3DMGnkc9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:zDpWAHea9OkzKJ9nBfX4axZvfro false - sufficient binding region:711-828 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NZ94-2 uniprotkb:P11464-4 intact:EBI-16423037 intact:EBI-16423576|ensembl:ENSP00000244296 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:p11464-4(display_long)|uniprotkb:PSG1(gene name)|psi-mi:PSG1(display_short)|uniprotkb:B1G1(gene name synonym)|uniprotkb:PSBG1(gene name synonym)|uniprotkb:PSGGA(gene name synonym)|uniprotkb:CD66 antigen-like family member F(gene name synonym)|uniprotkb:Fetal liver non-specific cross-reactive antigen 1/2(gene name synonym)|uniprotkb:PSG95(gene name synonym)|uniprotkb:Pregnancy-specific beta-1 glycoprotein C/D(gene name synonym)|uniprotkb:PSG-1d(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424382|imex:IM-26157-163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:P11464(isoform-parent)|ensembl:ENSG00000231924(gene)|ensembl:ENST00000244296(transcript)|intact:EBI-716740(isoform-parent) - - - figure legend:Table 1-37|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:H6tQwUo4u2VMd2HhJDO28kdJeVY9606 rigid:swiYHzMxaxHnw8oJR6a8f/wpXyY false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16557 uniprotkb:Q9NZ94-2 intact:EBI-7222484|intact:MINT-1186118|uniprotkb:Q9UPL4|uniprotkb:Q08265|uniprotkb:Q9UQ77|uniprotkb:Q9BRW2|ensembl:ENSP00000332215|ensembl:ENSP00000480223 intact:EBI-16423037 psi-mi:psg3_human(display_long)|uniprotkb:PSG3(gene name)|psi-mi:PSG3(display_short)|uniprotkb:Carcinoembryonic antigen SG5(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424388|imex:IM-26157-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066296.2|ensembl:ENSG00000221826(gene)|ensembl:ENST00000327495(transcript)|ensembl:ENST00000614582(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0006952"(defense response)|go:"GO:0007565"(female pregnancy)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-202733|interpro:IPR003599(Immunoglobulin subtype) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - comment:mint|comment:homomint - figure legend:Table 1-38|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:gbRuqIlzzosHJl7gad++bJWwyHE9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:UsF+/JYUkzCKnY13Lf08M+9Kh2A false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q00888-1 intact:EBI-16423037 intact:EBI-16423587 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q00888-1(display_long)|uniprotkb:PSG4(gene name)|psi-mi:PSG4(display_short)|uniprotkb:CGM4(gene name synonym)|uniprotkb:PSG9(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424394|imex:IM-26157-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q00888(isoform-parent) - - - figure legend:Table 1-39|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:YYvGU3/+/SUy6jLARQnviakEe/s9606 rigid:VqXgCpoDttzd6OcsSznuiSuSxAA false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q15238 intact:EBI-16423037 intact:EBI-4314891|uniprotkb:Q15239|uniprotkb:Q96QJ1|uniprotkb:Q9UQ75|ensembl:ENSP00000344413|ensembl:ENSP00000382334|ensembl:ENSP00000386008 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:psg5_human(display_long)|uniprotkb:PSG5(gene name)|psi-mi:PSG5(display_short)|uniprotkb:Fetal liver non-specific cross-reactive antigen 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424400|imex:IM-26157-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_001123486.1|refseq:NP_002772.3|refseq:XP_016882492.1|ensembl:ENSG00000204941(gene)|ensembl:ENST00000342951(transcript)|ensembl:ENST00000366175(transcript)|ensembl:ENST00000407356(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007565"(female pregnancy)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-202733 - - - figure legend:Table 1-40|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:O5maHM77+s2CWMD1oFv4jzy80G49606 rigid:qeGTc5H7loswlw0nYmgtZSwRMCk false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15274 uniprotkb:Q9NZ94-2 intact:EBI-739851|uniprotkb:Q53XW7|uniprotkb:Q96G22|uniprotkb:Q9BSG6|ensembl:ENSP00000378782|ensembl:ENSP00000404873 intact:EBI-16423037 psi-mi:nadc_human(display_long)|uniprotkb:QPRT(gene name)|psi-mi:QPRT(display_short)|uniprotkb:Quinolinate phosphoribosyltransferase [decarboxylating](gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424406|imex:IM-26157-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055113.2|refseq:NP_001305178.1|refseq:NP_001305179.1|ensembl:ENSG00000103485(gene)|ensembl:ENST00000395384(transcript)|ensembl:ENST00000449759(transcript)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0034213"(quinolinate catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902494"(catalytic complex)|interpro:IPR002638(Quinolinate phosphoribosyl transferase)|interpro:IPR004393(Nicotinate-nucleotide pyrophosphorylase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR022412|interpro:IPR027277|interpro:IPR036068|interpro:IPR037128|rcsb pdb:2JBM|rcsb pdb:4KWV|rcsb pdb:4KWW|rcsb pdb:5AYX|rcsb pdb:5AYY|rcsb pdb:5AYZ|reactome:R-HSA-196807 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-43|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:ayjZsjJprp+eirEIN5VqDHmIzoA9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:GJqe71bl5y5Hl12MEa6Kc5lU69w false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q9C010-1 intact:EBI-16423037 intact:EBI-16423508|ensembl:ENSP00000346227|ensembl:ENSP00000357433|ensembl:ENSP00000357437|ensembl:ENSP00000376280|ensembl:ENSP00000376281 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q9c010-1(display_long)|uniprotkb:PKIB(gene name)|psi-mi:PKIB(display_short)|uniprotkb:PRKACN2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424412|imex:IM-26157-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q9C010(isoform-parent)|ensembl:ENSG00000135549(gene)|ensembl:ENST00000354275(transcript)|ensembl:ENST00000368448(transcript)|ensembl:ENST00000368452(transcript)|ensembl:ENST00000392490(transcript)|ensembl:ENST00000392491(transcript)|intact:EBI-3912499(isoform-parent) - - - figure legend:Table 1-33|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:svORJ5YnQvam7CC8WDVHny0E+PE9606 rigid:FA1bo+XWvcwoyB8UX5KjHgQaLWQ false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q15147-4 intact:EBI-16423037 intact:EBI-16423529 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q15147-4(display_long)|uniprotkb:PLCB4(gene name)|psi-mi:PLCB4(display_short) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424418|imex:IM-26157-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q15147(isoform-parent) - - - figure legend:Table 1-35|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:UTeUq2LxYdyBB5nYWz2vFtDzbFw9606 rigid:Z+WcraQEecbmRjnlENpmPFojCyY false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:P07602-3 intact:EBI-16423037 intact:EBI-16423568 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:p07602-3(display_long)|uniprotkb:Proactivator polypeptide(gene name synonym)|uniprotkb:PSAP(gene name)|psi-mi:PSAP(display_short)|uniprotkb:GLBA(gene name synonym)|uniprotkb:SAP1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424376|imex:IM-26157-233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:P07602(isoform-parent)|intact:EBI-716699(isoform-parent) - - - figure legend:Table 1-36|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:W6Os8JS5CxY91pyescyMS1idBX89606 rigid:rUd1mLjQMj70XAYC0nGGEzq+BjU false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q9Y613 intact:EBI-16423037 intact:EBI-348433|ensembl:ENSP00000258201|uniprotkb:Q59F76|uniprotkb:Q6Y1F2|uniprotkb:Q76MS8|uniprotkb:Q8N521 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:fhod1_human(display_long)|uniprotkb:FHOD1(gene name)|psi-mi:FHOD1(display_short)|uniprotkb:FHOS(gene name synonym)|uniprotkb:FHOS1(gene name synonym)|uniprotkb:Formin homolog overexpressed in spleen 1(gene name synonym)|uniprotkb:Formin homology 2 domain-containing protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424528|imex:IM-26157-197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_037373.2|ensembl:ENSG00000135723(gene)|ensembl:ENST00000258201(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007097"(nuclear migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032059"(bleb)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051015"(actin filament binding)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0051660"(establishment of centrosome localization)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027647|interpro:IPR041387|interpro:IPR042201|rcsb pdb:3DAD|rcsb pdb:6XF1|rcsb pdb:6XF2|mint:Q9Y613|dip:DIP-31134N - - - figure legend:Table 1-17|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:8zGurHJ5FL9gvqZazyRAHElMAdI9606 rigid:6pp2K75HhvfJKKq9IXsBlZ41RNQ false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q8NHA8 intact:EBI-16423037 intact:EBI-16423482 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:or1fc_human(display_long)|uniprotkb:Hs6M1-35P(gene name synonym)|uniprotkb:OR1F12(gene name)|psi-mi:OR1F12(display_short)|uniprotkb:OR1F12P(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424424|imex:IM-26157-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004984"(olfactory receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-381753|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR000725(Olfactory receptor) - - - figure legend:Table 1-32|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:ad4UlRZMXszO70AkdwoQXKh0Vr09606 rigid:u5oH7RUkKn8P24uUANZ9EMdv67s false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P05187 uniprotkb:Q9NZ94-2 intact:EBI-1211484|uniprotkb:P05188|uniprotkb:P06861|uniprotkb:Q53S78|uniprotkb:Q96DB7|ensembl:ENSP00000375881 intact:EBI-16423037 psi-mi:ppb1_human(display_long)|uniprotkb:ALPP(gene name)|psi-mi:ALPP(display_short)|uniprotkb:PLAP(gene name synonym)|uniprotkb:Placental alkaline phosphatase 1(gene name synonym)|uniprotkb:Alkaline phosphatase Regan isozyme(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424431|imex:IM-26157-165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001623.3|ensembl:ENSG00000163283(gene)|ensembl:ENST00000392027(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR001952(Alkaline phosphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR018299|mint:P05187|rcsb pdb:1EW2|rcsb pdb:1ZEB|rcsb pdb:1ZED|rcsb pdb:1ZEF|rcsb pdb:2GLQ|rcsb pdb:3MK0|rcsb pdb:3MK1|rcsb pdb:3MK2|reactome:R-HSA-6811438 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:JtfGSKMzJL3vP08X7lDS117PYbY9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:YZiXETdY0dFfkd+9KgmuZTJsA2Q false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49753-1 uniprotkb:Q9NZ94-2 intact:EBI-16423051 intact:EBI-16423037 psi-mi:p49753-1(display_long)|uniprotkb:ACOT2(gene name)|psi-mi:ACOT2(display_short)|uniprotkb:PTE2(gene name synonym)|uniprotkb:PTE2A(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424438|imex:IM-26157-235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P49753(isoform-parent) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:3a++2vHE7Zr553F/LJ68pxvJ/289606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:RjGVqSih3ZmVOe9XVMZzbsUGuMo false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P18848 uniprotkb:Q9NZ94-2 intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3 intact:EBI-16423037 psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424444|imex:IM-26157-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists." - figure legend:Table 1-4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:2UolKWXxKFddysaOo70/U/1pI5k9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:quBzsIRsmeRms+Bej0tQnGfBpMY false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O94973-2 uniprotkb:Q9NZ94-2 intact:EBI-10981066|ensembl:ENSP00000327694 intact:EBI-16423037 psi-mi:o94973-2(display_long)|uniprotkb:AP2A2(gene name)|psi-mi:AP2A2(display_short)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:ADTAB(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:CLAPA2(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:HIP9(gene name synonym)|uniprotkb:HYPJ(gene name synonym)|uniprotkb:Huntingtin yeast partner J(gene name synonym)|uniprotkb:Huntingtin-interacting protein 9(gene name synonym)|uniprotkb:Huntingtin-interacting protein J(gene name synonym)|uniprotkb:KIAA0899(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424450|imex:IM-26157-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642835(isoform-parent)|uniprotkb:O94973-2(isoform-parent)|ensembl:ENSG00000183020(gene)|ensembl:ENST00000332231(transcript) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - isoform-comment:No experimental confirmation available. - figure legend:Table 1-3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:bphgc5OtLeh97dypM1kuRa9VDGM9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:Ni8Qno51NBRh0rdr5jJxT/gR3Qs false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02745 uniprotkb:Q9NZ94-2 intact:EBI-1220209|uniprotkb:Q5T963|uniprotkb:B2R4X2|ensembl:ENSP00000363773|ensembl:ENSP00000385564 intact:EBI-16423037 psi-mi:c1qa_human(display_long)|uniprotkb:C1QA(gene name)|psi-mi:C1QA(display_short) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424456|imex:IM-26157-131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057075.1|refseq:NP_001334394.1|refseq:NP_001334395.1|ensembl:ENSG00000173372(gene)|ensembl:ENST00000374642(transcript)|ensembl:ENST00000402322(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005602"(complement component C1 complex)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007568"(aging)|go:"GO:0010039"(response to iron ion)|go:"GO:0016322"(neuron remodeling)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0048143"(astrocyte activation)|go:"GO:0050808"(synapse organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098794"(postsynapse)|go:"GO:0098883"(synapse pruning)|go:"GO:0150062"(complement-mediated synapse pruning)|go:"GO:0150064"(vertebrate eye-specific patterning)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR037572|rcsb pdb:1PK6|rcsb pdb:2JG8|rcsb pdb:2JG9|rcsb pdb:2WNU|rcsb pdb:2WNV|rcsb pdb:5HKJ|rcsb pdb:5HZF|rcsb pdb:6FCZ|rcsb pdb:6Z6V|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-977606 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:JOnVJ11QPTmKEEGIr3BAlb2j6+s9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:JxMx0JXTKY6a3DnbsevcWy5FYfk false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6ZSJ8-2 uniprotkb:Q9NZ94-2 intact:EBI-16423088 intact:EBI-16423037 psi-mi:q6zsj8-2(display_long)|uniprotkb:C1orf122(gene name)|psi-mi:C1orf122(display_short) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424462|imex:IM-26157-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZSJ8(isoform-parent) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:jjGNGUUDS3QEO6VYxB4LcQnLtdI9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:0bWjWpLuy2/m1iMFvrTFXU8d+r0 false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N163-1 uniprotkb:Q9NZ94-2 intact:EBI-1021318|ensembl:ENSP00000310670|ensembl:ENSP00000373930 intact:EBI-16423037 psi-mi:q8n163-1(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424468|imex:IM-26157-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-355410(q8n163_human)|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:U3SK1q/WSCZR+uGbN6LGZxGVPgc false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:P0DN86-1 intact:EBI-16423037 intact:EBI-16423210 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:p0dn86-1(display_long)|uniprotkb:CGB3(gene name)|psi-mi:CGB3(display_short)|uniprotkb:CGB(gene name synonym)|uniprotkb:CGB5(gene name)|psi-mi:CGB5(display_short)|uniprotkb:CGB8(gene name)|psi-mi:CGB8(display_short) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424474|imex:IM-26157-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:P0DN86(isoform-parent) - - - figure legend:Table 1-8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:Fg4f/QYLQ+ZjWmJ1xx/ZNXwdvi89606 rigid:wdHiqka5keQdg5xCbB8DSQ9k4zo false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:P07339 intact:EBI-16423037 intact:EBI-2115097|uniprotkb:Q6IB57|ensembl:ENSP00000236671 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:catd_human(display_long)|uniprotkb:CTSD(gene name)|psi-mi:CTSD(display_short)|uniprotkb:CPSD(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424480|imex:IM-26157-195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_001900.1|dip:DIP-43906N|ensembl:ENSG00000117984(gene)|ensembl:ENST00000236671(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070001"(aspartic-type peptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033144|mint:P07339|rcsb pdb:1LYA|rcsb pdb:1LYB|rcsb pdb:1LYW|rcsb pdb:4OBZ|rcsb pdb:4OC6|rcsb pdb:4OD9|reactome:R-HSA-1442490|reactome:R-HSA-2022377|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-9018519 - - - figure legend:Table 1-9|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:M1qLQBlL2DSCZiAwIPee9Vza3dU9606 rigid:JXaFcfZ0thzbqEfW6JJ8WoJvasg false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:P54368 intact:EBI-16423037 intact:EBI-948441|ensembl:ENSP00000473381|uniprotkb:O43382|uniprotkb:Q14989|uniprotkb:Q92595|uniprotkb:Q9UPL9 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:oaz1_human(display_long)|uniprotkb:OAZ1(gene name)|psi-mi:OAZ1(display_short)|uniprotkb:OAZ(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424612|imex:IM-26157-207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) ensembl:ENSG00000104904(gene)|ensembl:ENST00000602676(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008073"(ornithine decarboxylase inhibitor activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:1902268"(negative regulation of polyamine transmembrane transport)|interpro:IPR002993(Ornithine decarboxylase antizyme)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR029914|mint:P54368|rcsb pdb:4ZGY|rcsb pdb:4ZGZ|rcsb pdb:5BWA|reactome:R-HSA-350562|interpro:IPR038581|refseq:NP_004143.1 - - - figure legend:Table 1-31|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:rrf1LoIm0F76PUQlVAva8tbH+w49606 rigid:s+gEhdYK/n7MgxYEx5cp1UuAYT8 false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:O43847 intact:EBI-16423037 intact:EBI-2371631|uniprotkb:O15241|uniprotkb:O15242|uniprotkb:Q5VUL0|uniprotkb:Q96HB2|uniprotkb:Q9NU57|uniprotkb:A6NI41|ensembl:ENSP00000262679|intact:EBI-6137671 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:nrdc_human(display_long)|uniprotkb:NRDC(gene name)|psi-mi:NRDC(display_short)|uniprotkb:N-arginine dibasic convertase(gene name synonym)|uniprotkb:NRD1(gene name synonym)|uniprotkb:Nardilysin convertase(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424606|imex:IM-26157-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_001095132.1|refseq:NP_001229290.1|refseq:NP_002516.2|ensembl:ENSG00000078618(gene)|ensembl:ENST00000352171(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0009986"(cell surface)|go:"GO:0046872"(metal ion binding)|go:"GO:0048408"(epidermal growth factor binding)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR032632|mint:O43847 - - - figure legend:Table 1-30|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2018/10/11 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:zvZTk2Q799M8nsREOYmuYPF/x1U9606 rigid:j8ijqpbMJA1ZhncUWin3fILLi3U false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q14934-3 intact:EBI-16423037 intact:EBI-16423423 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q14934-3(display_long)|uniprotkb:NFATC4(gene name)|psi-mi:NFATC4(display_short)|uniprotkb:NFAT3(gene name synonym)|uniprotkb:IA-IXi(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424600|imex:IM-26157-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q14934(isoform-parent) - - - figure legend:Table 1-29|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:Ogk9Y8Gc5YcV4Y3QJArCE18YZ2A9606 rigid:Mb9FlAS3ESs3cwr3K3Yr8DPvo90 false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00403 uniprotkb:Q9NZ94-2 intact:EBI-2105756|uniprotkb:Q37526|ensembl:ENSP00000354876 intact:EBI-16423037 psi-mi:cox2_human(display_long)|uniprotkb:MT-CO2(gene name)|psi-mi:MT-CO2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:COXII(gene name synonym)|uniprotkb:MTCO2(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:COX2(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424594|imex:IM-26157-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_003024029.1|ensembl:ENSG00000198712(gene)|ensembl:ENST00000361739(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00403|rcsb pdb:3VRJ|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:NyMmciQe53E935KEZahz8cGPjIM9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:kmmfWUMSdAkbx/RcLUzTmYGBr6Q false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q9BRT3 intact:EBI-16423037 intact:EBI-6137472|ensembl:ENSP00000377778 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:mien1_human(display_long)|uniprotkb:MIEN1(gene name)|psi-mi:MIEN1(display_short)|uniprotkb:C17orf37(gene name synonym)|uniprotkb:RDX12(gene name synonym)|uniprotkb:XTP4(gene name synonym)|uniprotkb:HBV X-transactivated gene 4 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 4(gene name synonym)|uniprotkb:Protein C35(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424588|imex:IM-26157-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_115715.3|refseq:NP_001317135.1|ensembl:ENSG00000141741(gene)|ensembl:ENST00000394231(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0010269"(response to selenium ion)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051491"(positive regulation of filopodium assembly)|interpro:IPR011893(SelT/selW/selH selenoprotein)|interpro:IPR036249|rcsb pdb:2LJK - - - figure legend:Table 1-27|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:ViTKcje+j8lSpoS24M+Mn05tm0U9606 rigid:KRDLiMiawKDcTYw7x/4r5zrSrEk false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q66K74-1 intact:EBI-16423037 intact:EBI-16423404 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q66k74-1(display_long)|uniprotkb:MAP1S(gene name)|psi-mi:MAP1S(display_short)|uniprotkb:BPY2IP1(gene name synonym)|uniprotkb:C19orf5(gene name synonym)|uniprotkb:MAP8(gene name synonym)|uniprotkb:VCY2IP1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424582|imex:IM-26157-133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q66K74(isoform-parent) - - - figure legend:Table 1-26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:f+UnRFHFEFKp2fTRCHt4/HXtnFQ9606 rigid:i8w3CEtfTEFQeeZmbt8JQmGqrbk false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q9NTJ4-1 intact:EBI-16423037 intact:EBI-16423365 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q9ntj4-1(display_long)|uniprotkb:MAN2C1(gene name)|psi-mi:MAN2C1(display_short)|uniprotkb:MANA(gene name synonym)|uniprotkb:MANA1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424576|imex:IM-26157-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q9NTJ4(isoform-parent) - - - figure legend:Table 1-25|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:czl0+oYTt//dDjYu1Q0zf5BPYss9606 rigid:g8x6Lel5Gv2LeHCAO9TiPvrLAGY false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:P09382 intact:EBI-16423037 intact:EBI-1048875|uniprotkb:B2R5E8|uniprotkb:Q9UDK5|ensembl:ENSP00000215909 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:leg1_human(display_long)|uniprotkb:Lectin galactoside-binding soluble 1(gene name synonym)|uniprotkb:Beta-galactoside-binding lectin L-14-I(gene name synonym)|uniprotkb:S-Lac lectin 1(gene name synonym)|uniprotkb:Galaptin(gene name synonym)|uniprotkb:14 kDa lectin(gene name synonym)|uniprotkb:HPL(gene name synonym)|uniprotkb:HBL(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM12(gene name synonym)|uniprotkb:LGALS1(gene name)|psi-mi:LGALS1(display_short)|uniprotkb:Lactose-binding lectin 1(gene name synonym)|uniprotkb:14 kDa laminin-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424570|imex:IM-26157-205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_002296.1|ensembl:ENST00000215909(transcript)|go:"GO:0002317"(plasma cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030395"(lactose binding)|ensembl:ENSG00000100097(gene)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P09382|rcsb pdb:1GZW|rcsb pdb:1W6M|rcsb pdb:1W6N|rcsb pdb:1W6O|rcsb pdb:1W6P|rcsb pdb:1W6Q|rcsb pdb:2KM2|rcsb pdb:2ZKN|rcsb pdb:3OY8|rcsb pdb:3OYW|rcsb pdb:3T2T|rcsb pdb:3W58|rcsb pdb:3W59|rcsb pdb:4Q1P|go:"GO:0031295"(T cell costimulation)|go:"GO:0034120"(positive regulation of erythrocyte aggregation)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043236"(laminin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0048678"(response to axon injury)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4Q1R|rcsb pdb:4Q26|rcsb pdb:4Q27|rcsb pdb:4Q2F|rcsb pdb:4XBL|rcsb pdb:4Y1U|rcsb pdb:4Y1V|rcsb pdb:4Y1X|rcsb pdb:4Y1Y|rcsb pdb:4Y1Z|rcsb pdb:4Y20|rcsb pdb:4Y22|rcsb pdb:4Y24|rcsb pdb:5MWT|rcsb pdb:5MWX|rcsb pdb:6B94|rcsb pdb:6F83|rcsb pdb:6M5Y|reactome:R-HSA-381426|reactome:R-HSA-8957275|dip:DIP-46153N - - - figure legend:Table 1-24|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:Sov3RfY2NOjdjuvdFlEd/vaNTMY9606 rigid:vUlo+Od67P5lskp6z0Ouh/DyAFU false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q8IWB1 intact:EBI-16423037 intact:EBI-2556412|uniprotkb:Q5JU17|uniprotkb:Q96MS8|uniprotkb:Q9C0A9|uniprotkb:D3DRA5|ensembl:ENSP00000278071|ensembl:ENSP00000337178|ensembl:ENSP00000350915|ensembl:ENSP00000497746 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:ipri_human(display_long)|uniprotkb:DANGER(gene name synonym)|uniprotkb:KIAA1754(gene name synonym)|uniprotkb:Protein DANGER(gene name synonym)|uniprotkb:ITPRIP(gene name)|psi-mi:ITPRIP(display_short) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424564|imex:IM-26157-171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_203755.1|ensembl:ENSG00000148841(gene)|ensembl:ENST00000278071(transcript)|ensembl:ENST00000337478(transcript)|ensembl:ENST00000358187(transcript)|ensembl:ENST00000647721(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR024797|interpro:IPR024810|interpro:IPR026250|refseq:NP_001258941.1|refseq:NP_001258942.1 - - - figure legend:Table 1-23|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:wTUAsA+dqm1wkrs9z4E7a4PdcLk9606 rigid:Qg7lZWMJ0Ogfk/wXcJx6Z1cb0W4 false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q8IV36-1 intact:EBI-16423037 intact:EBI-16423357 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q8iv36-1(display_long)|uniprotkb:HID1(gene name)|psi-mi:HID1(display_short)|uniprotkb:C17orf28(gene name synonym)|uniprotkb:DMC1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424558|imex:IM-26157-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q8IV36(isoform-parent) - - - figure legend:Table 1-22|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:JbuUtArSvjy+ToF/IuqCDBvZb/Q9606 rigid:eK9slumxiUcPpxZt4PAjgs+kw7Q false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q16774-2 intact:EBI-16423037 intact:EBI-16423350 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q16774-2(display_long)|uniprotkb:GUK1(gene name)|psi-mi:GUK1(display_short)|uniprotkb:GMK(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424552|imex:IM-26157-169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q16774(isoform-parent) - - - figure legend:Table 1-21|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:JTehFfJfLTl3HHYVvw26cEpIOCw9606 rigid:Rl9WliYO6MFwwUBo3GMiI1tlRK0 false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q99988 intact:EBI-16423037 intact:EBI-2116863|uniprotkb:O14629|uniprotkb:P78360|uniprotkb:Q9NRT0|uniprotkb:Q9BWA0|ensembl:ENSP00000252809 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:gdf15_human(display_long)|uniprotkb:GDF15(gene name)|psi-mi:GDF15(display_short)|uniprotkb:MIC1(gene name synonym)|uniprotkb:PDF(gene name synonym)|uniprotkb:PLAB(gene name synonym)|uniprotkb:PTGFB(gene name synonym)|uniprotkb:Placental bone morphogenetic protein(gene name synonym)|uniprotkb:Placental TGF-beta(gene name synonym)|uniprotkb:Macrophage inhibitory cytokine 1(gene name synonym)|uniprotkb:Prostate differentiation factor(gene name synonym)|uniprotkb:NSAID-activated gene 1 protein(gene name synonym)|uniprotkb:NSAID-regulated gene 1 protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424546|imex:IM-26157-199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_004855.2|ensembl:ENSG00000130513(gene)|ensembl:ENST00000252809(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002023"(reduction of food intake in response to dietary excess)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008083"(growth factor activity)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035860"(glial cell-derived neurotrophic factor receptor signaling pathway)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060400"(negative regulation of growth hormone receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070700"(BMP receptor binding)|go:"GO:1901741"(positive regulation of myoblast fusion)|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR029034|rcsb pdb:5VT2|rcsb pdb:5VZ3|rcsb pdb:5VZ4|rcsb pdb:6Q2J - - - figure legend:Table 1-20|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:W0oAT+oBcB2pzGNCol0EAfF7CqA9606 rigid:XxxMHT+d4fkbTnZ9osCBJEOF1hg false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21333-2 uniprotkb:Q9NZ94-2 intact:EBI-9641086|ensembl:ENSP00000353467 intact:EBI-16423037 psi-mi:p21333-2(display_long)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424540|imex:IM-26157-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-350432(isoform-parent)|ensembl:ENSG00000196924(gene)|ensembl:ENST00000360319(transcript)|uniprotkb:P21333-2(isoform-parent) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - isoform-comment:No experimental confirmation available. - figure legend:Table 1-19|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:r3XEZc6gmq37vSWBuSgyVvIf7Sc9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:VY2nzgTSoqwBepCTkhkeAjgogZc false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:P62942 intact:EBI-16423037 intact:EBI-1027571|uniprotkb:P20071|uniprotkb:Q4VC47|uniprotkb:Q6FGD9|uniprotkb:Q6LEU3|uniprotkb:Q9H103|uniprotkb:Q9H566|uniprotkb:D3DVW6|ensembl:ENSP00000371138|ensembl:ENSP00000371143|ensembl:ENSP00000383003|ensembl:ENSP00000503033|ensembl:ENSP00000503152 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:fkb1a_human(display_long)|uniprotkb:FKBP1A(gene name)|psi-mi:FKBP1A(display_short)|uniprotkb:FKBP1(gene name synonym)|uniprotkb:FKBP12(gene name synonym)|uniprotkb:FK506-binding protein 1A(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Immunophilin FKBP12(gene name synonym)|uniprotkb:12 kDa FK506-binding protein(gene name synonym)|uniprotkb:Calstabin-1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424534|imex:IM-26157-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) ensembl:ENSG00000088832(gene)|ensembl:ENST00000381719(transcript)|ensembl:ENST00000381724(transcript)|ensembl:ENST00000400137(transcript)|ensembl:ENST00000677335(transcript)|ensembl:ENST00000678408(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005527"(macrolide binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0014802"(terminal cisterna)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030018"(Z disc)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031312"(extrinsic component of organelle membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0042026"(protein refolding)|go:"GO:0042110"(T cell activation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0048185"(activin binding)|go:"GO:0050776"(regulation of immune response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1A7X|rcsb pdb:1B6C|rcsb pdb:1BKF|rcsb pdb:1BL4|rcsb pdb:1D6O|rcsb pdb:1D7H|rcsb pdb:1D7I|rcsb pdb:1D7J|rcsb pdb:1EYM|rcsb pdb:1F40|rcsb pdb:1FAP|rcsb pdb:1FKB|rcsb pdb:1FKD|rcsb pdb:1FKF|rcsb pdb:1FKG|rcsb pdb:1FKH|rcsb pdb:1FKI|rcsb pdb:2DG4|rcsb pdb:2DG9|rcsb pdb:2FAP|rcsb pdb:2FKE|rcsb pdb:2ND5|rcsb pdb:2PPN|rcsb pdb:2PPO|rcsb pdb:2PPP|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:1FKJ|rcsb pdb:3H9R|rcsb pdb:3MDY|rcsb pdb:4DH0|rcsb pdb:4FAP|rcsb pdb:1FKR|rcsb pdb:4IPX|rcsb pdb:4N19|rcsb pdb:4ODP|rcsb pdb:4ODQ|rcsb pdb:4ODR|rcsb pdb:5I7P|rcsb pdb:5I7Q|rcsb pdb:6I1S|rcsb pdb:1FKS|rcsb pdb:6M4U|rcsb pdb:6OQA|rcsb pdb:6VCU|rcsb pdb:6YF0|rcsb pdb:6YF1|rcsb pdb:6YF2|rcsb pdb:6YF3|reactome:R-HSA-166208|rcsb pdb:1FKT|reactome:R-HSA-2025928|reactome:R-HSA-2173789|reactome:R-HSA-2173791|reactome:R-HSA-3656535|rcsb pdb:1J4H|rcsb pdb:1J4I|reactome:R-HSA-9679191|rcsb pdb:1J4R|rcsb pdb:1NSG|rcsb pdb:1QPF|rcsb pdb:1QPL|rcsb pdb:2DG3|refseq:NP_000792.1|refseq:NP_463460.1|dip:DIP-29710N - - - figure legend:Table 1-18|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:3eikHNIIVs8AFM7PYVWurI/9KUY9606 rigid:OFNQhALy7xkoBJ/3pJYpkVSFdqQ false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:P23142 intact:EBI-16423037 intact:EBI-726652|uniprotkb:P23143|uniprotkb:P23144|uniprotkb:P37888|uniprotkb:Q5TIC4|uniprotkb:Q8TBH8|uniprotkb:Q9HBQ5|uniprotkb:Q9UC21|uniprotkb:Q9UGR4|uniprotkb:Q9UH41|uniprotkb:B0QY42|intact:EBI-2562209|ensembl:ENSP00000331544|uniprotkb:B1AHL4 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:fbln1_human(display_long)|uniprotkb:FBLN1(gene name)|psi-mi:FBLN1(display_short)|uniprotkb:PP213(orf name) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424522|imex:IM-26157-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_001987.2|refseq:NP_006476.2|refseq:NP_006477.2|refseq:NP_006478.2|ensembl:ENSG00000077942(gene)|ensembl:ENST00000327858(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007566"(embryo implantation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070051"(fibrinogen binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0071953"(elastic fiber)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904188"(negative regulation of transformation of host cell by virus)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000647"(negative regulation of stem cell proliferation)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR017048(Fibulin-1)|interpro:IPR018097|interpro:IPR026823|mint:P23142|reactome:R-HSA-2129379|go:"GO:0005201"(extracellular matrix structural constituent) - - - figure legend:Table 1-16|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:a47ZJLXWeghGIY9xJTQI7VujuMk9606 rigid:FUU2M2ME62UZ7QHqhnm/MQl+0b4 false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:O15287 intact:EBI-16423037 intact:EBI-81610|ensembl:ENSP00000367910 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:fancg_human(display_long)|uniprotkb:FANCG(gene name)|psi-mi:FANCG(display_short)|uniprotkb:XRCC9(gene name synonym)|uniprotkb:DNA repair protein XRCC9(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424516|imex:IM-26157-167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) ensembl:ENSG00000221829(gene)|refseq:NP_004620.1|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007286"(spermatid development)|go:"GO:0009314"(response to radiation)|ensembl:ENST00000378643(transcript)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039684|mint:O15287|rcsb pdb:7KZP|rcsb pdb:7KZQ|go:"GO:0001541"(ovarian follicle development)|rcsb pdb:7KZR|go:"GO:0003684"(damaged DNA binding)|rcsb pdb:7KZS|go:"GO:0005654"(nucleoplasm)|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|go:"GO:0005730"(nucleolus) - - - figure legend:Table 1-15|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:jVGeic2vn/qrZgro3IKXWhNteHo9606 rigid:1XibzCtRG4V0prGbywAchlBpYE4 false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:O43281-1 intact:EBI-16423037 intact:EBI-16423283|ensembl:ENSP00000216733 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:o43281-1(display_long)|uniprotkb:Cas scaffolding protein family member 3(gene name synonym)|uniprotkb:EFS(gene name)|psi-mi:EFS(display_short)|uniprotkb:CASS3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424510|imex:IM-26157-241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:O43281(isoform-parent)|ensembl:ENSG00000100842(gene)|ensembl:ENST00000216733(transcript)|intact:EBI-718488(isoform-parent) - - - figure legend:Table 1-14|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:7aO8sdSXU6RqHKK6NnxYRwcDet09606 rigid:jkhVNNTAYBHIkVP0Ye78TGxRGAU false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:P68104 intact:EBI-16423037 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424504|imex:IM-26157-113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table 1-13|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2020/08/15 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:2/pm0uiFKksVGTCswuMt30+c+T4 false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q9BY08-1 intact:EBI-16423037 intact:EBI-16423266 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q9by08-1(display_long)|uniprotkb:EBPL(gene name)|psi-mi:EBPL(display_short)|uniprotkb:EBRP(gene name synonym)|uniprotkb:ERP(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424498|imex:IM-26157-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q9BY08(isoform-parent) - - - figure legend:Table 1-12|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:ZloiP+PR+M6chD2wm/bc3bzItKU9606 rigid:TX4Tca70f2USNbrZDmezjPie30Q false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q9H4A9 intact:EBI-16423037 intact:EBI-2871328|uniprotkb:Q6UX92|uniprotkb:Q8TC95|uniprotkb:B2RCF8|uniprotkb:A0A024R6Y5|uniprotkb:B3KS59|uniprotkb:I3L248|ensembl:ENSP00000377430|ensembl:ENSP00000458977 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:dpep2_human(display_long)|uniprotkb:DPEP2(gene name)|psi-mi:DPEP2(display_short)|uniprotkb:UNQ284/PRO323(orf name) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424492|imex:IM-26157-237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_071750.1|ensembl:ENSG00000167261(gene)|ensembl:ENST00000393847(transcript)|ensembl:ENST00000572888(transcript)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006691"(leukotriene metabolic process)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0070573"(metallodipeptidase activity)|interpro:IPR000180(Peptidase M19, renal dipeptidase, active site)|interpro:IPR008257(Peptidase M19, renal dipeptidase)|interpro:IPR028531|interpro:IPR032466|reactome:R-HSA-2142691|reactome:R-HSA-5423646|reactome:R-HSA-9664535 - - - figure legend:Table 1-11|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2018/04/06 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:soBoETD/fTJQuFLrzBydim41He89606 rigid:YCm/2EKIhwKhPMsosUZmkIVskdA false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:P05108-1 intact:EBI-16423037 intact:EBI-16423235 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:p05108-1(display_long)|uniprotkb:CYP11A1(gene name)|psi-mi:CYP11A1(display_short)|uniprotkb:CYP11A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424486|imex:IM-26157-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:P05108(isoform-parent) - - - figure legend:Table 1-10|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:I/jdJNWgdU7vLkY+5PwcsKUnBNI9606 rigid:PN3EeV9/GpEnjOB7QksbsM9E+Nk false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47897-1 uniprotkb:Q9NZ94-2 intact:EBI-16424302|ensembl:ENSP00000307567 intact:EBI-16423037 psi-mi:p47897-1(display_long)|uniprotkb:QARS1(gene name)|psi-mi:QARS1(display_short)|uniprotkb:Glutaminyl-tRNA synthetase(gene name synonym)|uniprotkb:QARS(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424666|imex:IM-26157-115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000306125(transcript)|ensembl:ENSG00000172053(gene)|uniprotkb:P47897(isoform-parent)|intact:EBI-347462(isoform-parent) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-42|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:3Q8LR+aWJJue/ixtD3ZYDpC/D3o9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:NKUNtr7gB/Jx+t3i0+uzgq6sGY8 false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51571 uniprotkb:Q9NZ94-2 intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104 intact:EBI-16423037 psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424636|imex:IM-26157-245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-46|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:CX1uMBTW01+xxtQvf+HoBexguSA false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q9UQ72-1 intact:EBI-16423037 intact:EBI-16424294 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q9uq72-1(display_long)|uniprotkb:PSG11(gene name)|psi-mi:PSG11(display_short)|uniprotkb:PSG13(gene name synonym)|uniprotkb:PSG14(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424660|imex:IM-26157-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q9UQ72(isoform-parent) - - - figure legend:Table 1-41|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:5jzOv/gBiVrbHqNJnkBZSGxxcs89606 rigid:h/Bv8TF7YAhFjOL3TMNY8vaRBpY false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H3M7-1 uniprotkb:Q9NZ94-2 intact:EBI-11666025|ensembl:ENSP00000462521 intact:EBI-16423037 psi-mi:q9h3m7-1(display_long)|uniprotkb:TXNIP(gene name)|psi-mi:TXNIP(display_short)|uniprotkb:VDUP1(gene name synonym)|uniprotkb:Thioredoxin-binding protein 2(gene name synonym)|uniprotkb:Vitamin D3 up-regulated protein 1(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424654|imex:IM-26157-211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1369170(isoform-parent)|ensembl:ENSG00000265972(gene)|ensembl:ENST00000582401(transcript) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-49|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:jJMKfl1/92UPMTXBLCdu6NcYbjQ9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:ZxGVT49cBc+RI4vB3lAJKYmHkYU false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UPN9-1 uniprotkb:Q9NZ94-2 intact:EBI-16424351 intact:EBI-16423037 psi-mi:q9upn9-1(display_long)|uniprotkb:TRIM33(gene name)|psi-mi:TRIM33(display_short)|uniprotkb:KIAA1113(gene name synonym)|uniprotkb:RFG7(gene name synonym)|uniprotkb:TIF1G(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424648|imex:IM-26157-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9UPN9(isoform-parent) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-48|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:DB02UIWcpeneONPdG17AS08/9/A9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:JnHMW2e4rXY4wmm+p54tZ4PGAe0 false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43278-1 uniprotkb:Q9NZ94-2 intact:EBI-15822221|ensembl:ENSP00000342098 intact:EBI-16423037 psi-mi:o43278-1(display_long)|uniprotkb:UNQ223/PRO256(orf name)|uniprotkb:HAI-1B(isoform synonym)|uniprotkb:Hepatocyte growth factor activator inhibitor type 1(gene name synonym)|uniprotkb:SPINT1(gene name)|psi-mi:SPINT1(display_short)|uniprotkb:HAI1(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424630|imex:IM-26157-243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166145(gene)|ensembl:ENST00000344051(transcript)|intact:EBI-953990(isoform-parent) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-45|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:feHnyLQq6rOSG2IW9dCGVBkcurg9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:HDNI7DDe/qP9722F0vM08JQlaog false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:P31930 intact:EBI-16423037 intact:EBI-1052596|uniprotkb:Q96DD2|uniprotkb:B2R7R8|ensembl:ENSP00000203407 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:qcr1_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 1(gene name synonym)|uniprotkb:Complex III subunit 1(gene name synonym)|uniprotkb:UQCRC1(gene name)|psi-mi:UQCRC1(display_short)|uniprotkb:Core protein I(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424678|imex:IM-26157-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_003356.2|ensembl:ENSG00000010256(gene)|ensembl:ENST00000203407(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0014823"(response to activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P31930|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105 - - - figure legend:Table 1-51|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:7Yrm6OhOmgfHF5mAX3hT3DMGnkc9606 rigid:zDpWAHea9OkzKJ9nBfX4axZvfro false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BZV1-1 uniprotkb:Q9NZ94-2 intact:EBI-16424361 intact:EBI-16423037 psi-mi:q9bzv1-1(display_long)|uniprotkb:UBXN6(gene name)|psi-mi:UBXN6(display_short)|uniprotkb:UBXD1(gene name synonym)|uniprotkb:UBXDC2(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424672|imex:IM-26157-135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9BZV1(isoform-parent) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-50|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:bdhN1ftwK7aQRHUgkBTclJ/z3SQ9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:vuCyYpxYyxq18Jzy1QsKdUhFiyo false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96R06 uniprotkb:Q9NZ94-2 intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300 intact:EBI-16423037 psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424618|imex:IM-26157-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-44|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:dwbY4p8Dn/XrZSWpfxu1ML4n70Q false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZ94-2 uniprotkb:Q6P1J6-1 intact:EBI-16423037 intact:EBI-16423521|ensembl:ENSP00000330442 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:q6p1j6-1(display_long)|uniprotkb:Phospholipase B/lipase(gene name synonym)|uniprotkb:PLB1(gene name)|psi-mi:PLB1(display_short)|uniprotkb:PLB(gene name synonym)|uniprotkb:Lysophospholipase(gene name synonym)|uniprotkb:Phospholipase A2(gene name synonym)|uniprotkb:Triacylglycerol lipase(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424624|imex:IM-26157-173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) uniprotkb:Q6P1J6(isoform-parent)|ensembl:ENSG00000163803(gene)|ensembl:ENST00000327757(transcript)|intact:EBI-10757275(isoform-parent) - - - figure legend:Table 1-34|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:HouhRFRQLWDFlTa/FgjKK5Pxnp49606 rigid:pXjcpDPq/wjM6LMBTafKJzr5rvo false sufficient binding region:711-828 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P45378-2 uniprotkb:Q9NZ94-2 intact:EBI-16424344 intact:EBI-16423037 psi-mi:p45378-2(display_long)|uniprotkb:TNNT3(gene name)|psi-mi:TNNT3(display_short)|uniprotkb:Tnt3(isoform synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0018"(two hybrid) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424642|imex:IM-26157-209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P45378(isoform-parent)|uniprotkb:P45378-2(isoform-parent) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Table 1-47|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/09/21 2017/10/05 rogid:DqSRBaNIOwW6tqqsSuslL+L5PhA9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:DB89Lgq/jOMdMJ4PL4sk2EBec9o false - sufficient binding region:711-828 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49753 uniprotkb:Q9NZ94-2 intact:EBI-1052865|uniprotkb:Q3I5F8|uniprotkb:Q9NUX4|uniprotkb:Q53EK4|ensembl:ENSP00000238651 intact:EBI-16423037 psi-mi:acot2_human(display_long)|uniprotkb:Acyl-coenzyme A thioester hydrolase 2a(gene name synonym)|uniprotkb:Long-chain acyl-CoA thioesterase 2(gene name synonym)|uniprotkb:ZAP128(gene name synonym)|uniprotkb:CTE-Ia(gene name synonym)|uniprotkb:ACOT2(gene name)|psi-mi:ACOT2(display_short)|uniprotkb:PTE2(gene name synonym)|uniprotkb:PTE2A(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424692|imex:IM-26157-117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006812.3|ensembl:ENSG00000119673(gene)|ensembl:ENST00000238651(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|interpro:IPR006862(Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase)|interpro:IPR014940(BAAT/Acyl-CoA thioester hydrolase C-terminal)|interpro:IPR016662(Acyl-CoA thioesterase, long chain)|interpro:IPR029058|interpro:IPR042490|rcsb pdb:3HLK|reactome:R-HSA-77289|reactome:R-HSA-9033241 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Fig 3A-1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:3a++2vHE7Zr553F/LJ68pxvJ/289606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:RjGVqSih3ZmVOe9XVMZzbsUGuMo false green fluorescent protein tag:n-n sufficient binding region:711-828|myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P05108 uniprotkb:Q9NZ94-2 intact:EBI-7183136|uniprotkb:Q8N1A7|uniprotkb:Q15081|intact:MINT-1200919|uniprotkb:Q16805|uniprotkb:A8K8D5|uniprotkb:B3KPU8|uniprotkb:G3XAD7|ensembl:ENSP00000268053|ensembl:ENSP00000500767 intact:EBI-16423037 psi-mi:cp11a_human(display_long)|uniprotkb:CYP11A1(gene name)|psi-mi:CYP11A1(display_short)|uniprotkb:CYP11A(gene name synonym)|uniprotkb:Cytochrome P450 11A1(gene name synonym)|uniprotkb:CYPXIA1(gene name synonym)|uniprotkb:Cholesterol desmolase(gene name synonym)|uniprotkb:"Cytochrome P450(scc)"(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424702|imex:IM-26157-213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093243.1|refseq:NP_000772.2|ensembl:ENSG00000140459(gene)|ensembl:ENSG00000288362(gene)|ensembl:ENST00000268053(transcript)|ensembl:ENST00000672385(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006700"(C21-steroid hormone biosynthetic process)|go:"GO:0006704"(glucocorticoid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008386"("cholesterol monooxygenase (side-chain-cleaving) activity")|go:"GO:0016125"(sterol metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0034650"(cortisol metabolic process)|go:"GO:0042359"(vitamin D metabolic process)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|interpro:IPR033283|interpro:IPR036396|mint:P05108|rcsb pdb:3N9Y|rcsb pdb:3N9Z|rcsb pdb:3NA0|rcsb pdb:3NA1|reactome:R-HSA-196108|reactome:R-HSA-211976|reactome:R-HSA-5579026 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - comment:mint|function:Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone|comment:homomint|function:"Defects in CYP11A1 are a cause of congenital adrenal insufficiency (CAI)"|function:"Defects in CYP11A1 are a cause of congenital lipoid adrenal hyperplasia (CLAH) [MIM:201710]; also called lipoid CAH. CLAH is the most severe form of adrenal hyperplasia. This autosomal recessive and potentially lethal condition includes the onset of profound adrenocortical insufficiency shortly after birth, hyperpigmentation reflecting increased production of pro-opiomelanocortin, elevated plasma renin activity as a consequence of reduced aldosterone synthesis, and male pseudohermaphroditism resulting from deficient fetal testicular testosterone synthesis. CLAH is a rare disease, except in Japan and Korea where it accounts for a significant percentage of cases of congenital adrenal hyperplasia" - figure legend:Fig 3A-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:I/jdJNWgdU7vLkY+5PwcsKUnBNI9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:PN3EeV9/GpEnjOB7QksbsM9E+Nk false green fluorescent protein tag:n-n sufficient binding region:711-828|myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NZ94-2 uniprotkb:P68104 intact:EBI-16423037 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424712|imex:IM-26157-137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Fig 3A-3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:2/pm0uiFKksVGTCswuMt30+c+T4 false sufficient binding region:711-828|myc tag:n-n green fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NZ94-2 uniprotkb:Q86W33 intact:EBI-16423037 intact:EBI-16424742|ensembl:ENSP00000347748|ensembl:ENSP00000413428|ensembl:ENSP00000418298|ensembl:ENSP00000498161|uniprotkb:A8MVB8|uniprotkb:D3DNA9|uniprotkb:Q8WZ24|uniprotkb:Q96AJ6|uniprotkb:Q9P2R4 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:tpra1_human(display_long)|uniprotkb:TPRA1(gene name)|psi-mi:TPRA1(display_short)|uniprotkb:GPR175(gene name synonym)|uniprotkb:TMEM227(gene name synonym)|uniprotkb:Integral membrane protein GPR175(gene name synonym)|uniprotkb:Transmembrane protein 227(gene name synonym)|uniprotkb:PP6566(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424722|imex:IM-26157-139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) ensembl:ENSG00000163870(gene)|ensembl:ENST00000355552(transcript)|ensembl:ENST00000450633(transcript)|ensembl:ENST00000489960(transcript)|ensembl:ENST00000648957(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007568"(aging)|go:"GO:0016021"(integral component of membrane)|go:"GO:0040016"(embryonic cleavage)|go:"GO:1901991"(negative regulation of mitotic cell cycle phase transition)|interpro:IPR018781|refseq:NP_001129525.1|refseq:NP_001136118.1|refseq:XP_006713558.1|refseq:XP_006713559.1|refseq:XP_006713560.1|refseq:XP_011510724.1|refseq:XP_016861196.1|refseq:XP_016861197.1 - - - figure legend:Fig 3A-4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:W0wAO8/QNS/fAWQPl2AZC3oyQ8k9606 rigid:hn5zS7OjMibfvzBejFkoogaqXLY false sufficient binding region:711-828|myc tag:n-n green fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NZ94-2 uniprotkb:Q8IWB1 intact:EBI-16423037 intact:EBI-2556412|uniprotkb:Q5JU17|uniprotkb:Q96MS8|uniprotkb:Q9C0A9|uniprotkb:D3DRA5|ensembl:ENSP00000278071|ensembl:ENSP00000337178|ensembl:ENSP00000350915|ensembl:ENSP00000497746 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:ipri_human(display_long)|uniprotkb:DANGER(gene name synonym)|uniprotkb:KIAA1754(gene name synonym)|uniprotkb:Protein DANGER(gene name synonym)|uniprotkb:ITPRIP(gene name)|psi-mi:ITPRIP(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424732|imex:IM-26157-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_203755.1|ensembl:ENSG00000148841(gene)|ensembl:ENST00000278071(transcript)|ensembl:ENST00000337478(transcript)|ensembl:ENST00000358187(transcript)|ensembl:ENST00000647721(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR024797|interpro:IPR024810|interpro:IPR026250|refseq:NP_001258941.1|refseq:NP_001258942.1 - - - figure legend:Fig 3A-5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:wTUAsA+dqm1wkrs9z4E7a4PdcLk9606 rigid:Qg7lZWMJ0Ogfk/wXcJx6Z1cb0W4 false sufficient binding region:711-828|myc tag:n-n green fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NZ94-2 uniprotkb:Q86W33 intact:EBI-16423037 intact:EBI-16424742|ensembl:ENSP00000347748|ensembl:ENSP00000413428|ensembl:ENSP00000418298|ensembl:ENSP00000498161|uniprotkb:A8MVB8|uniprotkb:D3DNA9|uniprotkb:Q8WZ24|uniprotkb:Q96AJ6|uniprotkb:Q9P2R4 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:tpra1_human(display_long)|uniprotkb:TPRA1(gene name)|psi-mi:TPRA1(display_short)|uniprotkb:GPR175(gene name synonym)|uniprotkb:TMEM227(gene name synonym)|uniprotkb:Integral membrane protein GPR175(gene name synonym)|uniprotkb:Transmembrane protein 227(gene name synonym)|uniprotkb:PP6566(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424780|imex:IM-26157-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) ensembl:ENSG00000163870(gene)|ensembl:ENST00000355552(transcript)|ensembl:ENST00000450633(transcript)|ensembl:ENST00000489960(transcript)|ensembl:ENST00000648957(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007568"(aging)|go:"GO:0016021"(integral component of membrane)|go:"GO:0040016"(embryonic cleavage)|go:"GO:1901991"(negative regulation of mitotic cell cycle phase transition)|interpro:IPR018781|refseq:NP_001129525.1|refseq:NP_001136118.1|refseq:XP_006713558.1|refseq:XP_006713559.1|refseq:XP_006713560.1|refseq:XP_011510724.1|refseq:XP_016861196.1|refseq:XP_016861197.1 - - - figure legend:Fig 3B-1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:W0wAO8/QNS/fAWQPl2AZC3oyQ8k9606 rigid:hn5zS7OjMibfvzBejFkoogaqXLY false sufficient binding region:711-828|myc tag:n-n green fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P00403 uniprotkb:Q9NZ94-2 intact:EBI-2105756|uniprotkb:Q37526|ensembl:ENSP00000354876 intact:EBI-16423037 psi-mi:cox2_human(display_long)|uniprotkb:MT-CO2(gene name)|psi-mi:MT-CO2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:COXII(gene name synonym)|uniprotkb:MTCO2(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:COX2(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424790|imex:IM-26157-215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_003024029.1|ensembl:ENSG00000198712(gene)|ensembl:ENST00000361739(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00403|rcsb pdb:3VRJ|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Fig 3B-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:NyMmciQe53E935KEZahz8cGPjIM9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:kmmfWUMSdAkbx/RcLUzTmYGBr6Q false green fluorescent protein tag:n-n sufficient binding region:711-828|myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P05108 uniprotkb:Q9NZ94-2 intact:EBI-7183136|uniprotkb:Q8N1A7|uniprotkb:Q15081|intact:MINT-1200919|uniprotkb:Q16805|uniprotkb:A8K8D5|uniprotkb:B3KPU8|uniprotkb:G3XAD7|ensembl:ENSP00000268053|ensembl:ENSP00000500767 intact:EBI-16423037 psi-mi:cp11a_human(display_long)|uniprotkb:CYP11A1(gene name)|psi-mi:CYP11A1(display_short)|uniprotkb:CYP11A(gene name synonym)|uniprotkb:Cytochrome P450 11A1(gene name synonym)|uniprotkb:CYPXIA1(gene name synonym)|uniprotkb:Cholesterol desmolase(gene name synonym)|uniprotkb:"Cytochrome P450(scc)"(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424800|imex:IM-26157-175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093243.1|refseq:NP_000772.2|ensembl:ENSG00000140459(gene)|ensembl:ENSG00000288362(gene)|ensembl:ENST00000268053(transcript)|ensembl:ENST00000672385(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006700"(C21-steroid hormone biosynthetic process)|go:"GO:0006704"(glucocorticoid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008386"("cholesterol monooxygenase (side-chain-cleaving) activity")|go:"GO:0016125"(sterol metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0034650"(cortisol metabolic process)|go:"GO:0042359"(vitamin D metabolic process)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|interpro:IPR033283|interpro:IPR036396|mint:P05108|rcsb pdb:3N9Y|rcsb pdb:3N9Z|rcsb pdb:3NA0|rcsb pdb:3NA1|reactome:R-HSA-196108|reactome:R-HSA-211976|reactome:R-HSA-5579026 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - comment:mint|function:Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone|comment:homomint|function:"Defects in CYP11A1 are a cause of congenital adrenal insufficiency (CAI)"|function:"Defects in CYP11A1 are a cause of congenital lipoid adrenal hyperplasia (CLAH) [MIM:201710]; also called lipoid CAH. CLAH is the most severe form of adrenal hyperplasia. This autosomal recessive and potentially lethal condition includes the onset of profound adrenocortical insufficiency shortly after birth, hyperpigmentation reflecting increased production of pro-opiomelanocortin, elevated plasma renin activity as a consequence of reduced aldosterone synthesis, and male pseudohermaphroditism resulting from deficient fetal testicular testosterone synthesis. CLAH is a rare disease, except in Japan and Korea where it accounts for a significant percentage of cases of congenital adrenal hyperplasia" - figure legend:Fig 3B-3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:I/jdJNWgdU7vLkY+5PwcsKUnBNI9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:PN3EeV9/GpEnjOB7QksbsM9E+Nk false green fluorescent protein tag:n-n sufficient binding region:711-828|myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NZ94-2 uniprotkb:Q15274 intact:EBI-16423037 intact:EBI-739851|uniprotkb:Q53XW7|uniprotkb:Q96G22|uniprotkb:Q9BSG6|ensembl:ENSP00000378782|ensembl:ENSP00000404873 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:nadc_human(display_long)|uniprotkb:QPRT(gene name)|psi-mi:QPRT(display_short)|uniprotkb:Quinolinate phosphoribosyltransferase [decarboxylating](gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424810|imex:IM-26157-151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_055113.2|refseq:NP_001305178.1|refseq:NP_001305179.1|ensembl:ENSG00000103485(gene)|ensembl:ENST00000395384(transcript)|ensembl:ENST00000449759(transcript)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0034213"(quinolinate catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902494"(catalytic complex)|interpro:IPR002638(Quinolinate phosphoribosyl transferase)|interpro:IPR004393(Nicotinate-nucleotide pyrophosphorylase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR022412|interpro:IPR027277|interpro:IPR036068|interpro:IPR037128|rcsb pdb:2JBM|rcsb pdb:4KWV|rcsb pdb:4KWW|rcsb pdb:5AYX|rcsb pdb:5AYY|rcsb pdb:5AYZ|reactome:R-HSA-196807 - - - figure legend:Fig 3B-4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:ayjZsjJprp+eirEIN5VqDHmIzoA9606 rigid:GJqe71bl5y5Hl12MEa6Kc5lU69w false sufficient binding region:711-828|myc tag:n-n green fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NZ94-2 uniprotkb:P49753 intact:EBI-16423037 intact:EBI-1052865|uniprotkb:Q3I5F8|uniprotkb:Q9NUX4|uniprotkb:Q53EK4|ensembl:ENSP00000238651 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:acot2_human(display_long)|uniprotkb:Acyl-coenzyme A thioester hydrolase 2a(gene name synonym)|uniprotkb:Long-chain acyl-CoA thioesterase 2(gene name synonym)|uniprotkb:ZAP128(gene name synonym)|uniprotkb:CTE-Ia(gene name synonym)|uniprotkb:ACOT2(gene name)|psi-mi:ACOT2(display_short)|uniprotkb:PTE2(gene name synonym)|uniprotkb:PTE2A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424820|imex:IM-26157-217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_006812.3|ensembl:ENSG00000119673(gene)|ensembl:ENST00000238651(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|interpro:IPR006862(Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase)|interpro:IPR014940(BAAT/Acyl-CoA thioester hydrolase C-terminal)|interpro:IPR016662(Acyl-CoA thioesterase, long chain)|interpro:IPR029058|interpro:IPR042490|rcsb pdb:3HLK|reactome:R-HSA-77289|reactome:R-HSA-9033241 - - - figure legend:Fig 3B-5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:3a++2vHE7Zr553F/LJ68pxvJ/289606 rigid:RjGVqSih3ZmVOe9XVMZzbsUGuMo false sufficient binding region:711-828|myc tag:n-n green fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NZ94-2 uniprotkb:Q8IWB1 intact:EBI-16423037 intact:EBI-2556412|uniprotkb:Q5JU17|uniprotkb:Q96MS8|uniprotkb:Q9C0A9|uniprotkb:D3DRA5|ensembl:ENSP00000278071|ensembl:ENSP00000337178|ensembl:ENSP00000350915|ensembl:ENSP00000497746 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:ipri_human(display_long)|uniprotkb:DANGER(gene name synonym)|uniprotkb:KIAA1754(gene name synonym)|uniprotkb:Protein DANGER(gene name synonym)|uniprotkb:ITPRIP(gene name)|psi-mi:ITPRIP(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424831|imex:IM-26157-247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_203755.1|ensembl:ENSG00000148841(gene)|ensembl:ENST00000278071(transcript)|ensembl:ENST00000337478(transcript)|ensembl:ENST00000358187(transcript)|ensembl:ENST00000647721(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR024797|interpro:IPR024810|interpro:IPR026250|refseq:NP_001258941.1|refseq:NP_001258942.1 - - - figure legend:Fig 3B-6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:wTUAsA+dqm1wkrs9z4E7a4PdcLk9606 rigid:Qg7lZWMJ0Ogfk/wXcJx6Z1cb0W4 false sufficient binding region:711-828|myc tag:n-n green fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NZ94 uniprotkb:P00403 intact:EBI-3920184|uniprotkb:Q9NZ95|uniprotkb:Q9NZ96|uniprotkb:D3DVV0|uniprotkb:Q9NZ97|uniprotkb:Q9P248|uniprotkb:Q8NCD0|ensembl:ENSP00000351591|uniprotkb:D3DVV1|uniprotkb:B2RBK1|uniprotkb:D2X2H6|uniprotkb:Q86V51 intact:EBI-2105756|uniprotkb:Q37526|ensembl:ENSP00000354876 psi-mi:nlgn3_human(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:Gliotactin homolog(gene name synonym) psi-mi:cox2_human(display_long)|uniprotkb:MT-CO2(gene name)|psi-mi:MT-CO2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:COXII(gene name synonym)|uniprotkb:MTCO2(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:COX2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424857|brenda:"BTO:0000449"|imex:IM-26157-219 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0098793"(presynapse)|refseq:NP_001160132.1|refseq:NP_061850.2|refseq:NP_851820.1|ensembl:ENSG00000196338(gene)|ensembl:ENST00000358741(transcript)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007612"(learning)|go:"GO:0009986"(cell surface)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030534"(adult behavior)|go:"GO:0035176"(social behavior)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048675"(axon extension)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060024"(rhythmic synaptic transmission)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0071625"(vocalization behavior)|go:"GO:0089717"(spanning component of membrane)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098985"(asymmetric, glutamatergic, excitatory synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR000460(Neuroligin)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR019819|interpro:IPR029058|interpro:IPR030024|mint:Q9NZ94|reactome:R-HSA-6794361|go:"GO:0098983"(symmetric, GABA-ergic, inhibitory synapse)|refseq:NP_001308205.1 refseq:YP_003024029.1|ensembl:ENSG00000198712(gene)|ensembl:ENST00000361739(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00403|rcsb pdb:3VRJ|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-brain_cerebellum)|taxid:9606(human-human-brain_cerebellum) - 2017/09/21 2017/10/05 rogid:OzGAr78JAaopeMCBpHnhVXP5DaU9606 rogid:NyMmciQe53E935KEZahz8cGPjIM9606 rigid:e3rKTc4cUojHJyt9iDU1pBqHXzQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NZ94 uniprotkb:P68104 intact:EBI-3920184|uniprotkb:Q9NZ95|uniprotkb:Q9NZ96|uniprotkb:D3DVV0|uniprotkb:Q9NZ97|uniprotkb:Q9P248|uniprotkb:Q8NCD0|ensembl:ENSP00000351591|uniprotkb:D3DVV1|uniprotkb:B2RBK1|uniprotkb:D2X2H6|uniprotkb:Q86V51 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:nlgn3_human(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:Gliotactin homolog(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424857|brenda:"BTO:0000449"|imex:IM-26157-219 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0098793"(presynapse)|refseq:NP_001160132.1|refseq:NP_061850.2|refseq:NP_851820.1|ensembl:ENSG00000196338(gene)|ensembl:ENST00000358741(transcript)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007612"(learning)|go:"GO:0009986"(cell surface)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030534"(adult behavior)|go:"GO:0035176"(social behavior)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048675"(axon extension)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060024"(rhythmic synaptic transmission)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0071625"(vocalization behavior)|go:"GO:0089717"(spanning component of membrane)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098985"(asymmetric, glutamatergic, excitatory synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR000460(Neuroligin)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR019819|interpro:IPR029058|interpro:IPR030024|mint:Q9NZ94|reactome:R-HSA-6794361|go:"GO:0098983"(symmetric, GABA-ergic, inhibitory synapse)|refseq:NP_001308205.1 refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-brain_cerebellum)|taxid:9606(human-human-brain_cerebellum) - 2017/09/21 2017/10/05 rogid:OzGAr78JAaopeMCBpHnhVXP5DaU9606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:e3rKTc4cUojHJyt9iDU1pBqHXzQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NZ94 uniprotkb:P21333 intact:EBI-3920184|uniprotkb:Q9NZ95|uniprotkb:Q9NZ96|uniprotkb:D3DVV0|uniprotkb:Q9NZ97|uniprotkb:Q9P248|uniprotkb:Q8NCD0|ensembl:ENSP00000351591|uniprotkb:D3DVV1|uniprotkb:B2RBK1|uniprotkb:D2X2H6|uniprotkb:Q86V51 intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45 psi-mi:nlgn3_human(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:Gliotactin homolog(gene name synonym) psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16424857|brenda:"BTO:0000449"|imex:IM-26157-219 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0098793"(presynapse)|refseq:NP_001160132.1|refseq:NP_061850.2|refseq:NP_851820.1|ensembl:ENSG00000196338(gene)|ensembl:ENST00000358741(transcript)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007612"(learning)|go:"GO:0009986"(cell surface)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030534"(adult behavior)|go:"GO:0035176"(social behavior)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048675"(axon extension)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060024"(rhythmic synaptic transmission)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0071625"(vocalization behavior)|go:"GO:0089717"(spanning component of membrane)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098985"(asymmetric, glutamatergic, excitatory synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR000460(Neuroligin)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR019819|interpro:IPR029058|interpro:IPR030024|mint:Q9NZ94|reactome:R-HSA-6794361|go:"GO:0098983"(symmetric, GABA-ergic, inhibitory synapse)|refseq:NP_001308205.1 go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N - - - figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-brain_cerebellum)|taxid:9606(human-human-brain_cerebellum) - 2017/09/21 2017/10/05 rogid:OzGAr78JAaopeMCBpHnhVXP5DaU9606 rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606 rigid:e3rKTc4cUojHJyt9iDU1pBqHXzQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86W33 uniprotkb:Q9NZ94-2 intact:EBI-16424742|ensembl:ENSP00000347748|ensembl:ENSP00000413428|ensembl:ENSP00000418298|ensembl:ENSP00000498161|uniprotkb:A8MVB8|uniprotkb:D3DNA9|uniprotkb:Q8WZ24|uniprotkb:Q96AJ6|uniprotkb:Q9P2R4 intact:EBI-16423037 psi-mi:tpra1_human(display_long)|uniprotkb:TPRA1(gene name)|psi-mi:TPRA1(display_short)|uniprotkb:GPR175(gene name synonym)|uniprotkb:TMEM227(gene name synonym)|uniprotkb:Integral membrane protein GPR175(gene name synonym)|uniprotkb:Transmembrane protein 227(gene name synonym)|uniprotkb:PP6566(orf name) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0663"(confocal microscopy) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16424875|imex:IM-26157-153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163870(gene)|ensembl:ENST00000355552(transcript)|ensembl:ENST00000450633(transcript)|ensembl:ENST00000489960(transcript)|ensembl:ENST00000648957(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007568"(aging)|go:"GO:0016021"(integral component of membrane)|go:"GO:0040016"(embryonic cleavage)|go:"GO:1901991"(negative regulation of mitotic cell cycle phase transition)|interpro:IPR018781|refseq:NP_001129525.1|refseq:NP_001136118.1|refseq:XP_006713558.1|refseq:XP_006713559.1|refseq:XP_006713560.1|refseq:XP_011510724.1|refseq:XP_016861196.1|refseq:XP_016861197.1 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Fig 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:W0wAO8/QNS/fAWQPl2AZC3oyQ8k9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:hn5zS7OjMibfvzBejFkoogaqXLY false green fluorescent protein tag:n-n sufficient binding region:711-828|myc tag:n-n - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q9NZ94-2 uniprotkb:Q15274 intact:EBI-16423037 intact:EBI-739851|uniprotkb:Q53XW7|uniprotkb:Q96G22|uniprotkb:Q9BSG6|ensembl:ENSP00000378782|ensembl:ENSP00000404873 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:nadc_human(display_long)|uniprotkb:QPRT(gene name)|psi-mi:QPRT(display_short)|uniprotkb:Quinolinate phosphoribosyltransferase [decarboxylating](gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16424885|imex:IM-26157-177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_055113.2|refseq:NP_001305178.1|refseq:NP_001305179.1|ensembl:ENSG00000103485(gene)|ensembl:ENST00000395384(transcript)|ensembl:ENST00000449759(transcript)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0034213"(quinolinate catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902494"(catalytic complex)|interpro:IPR002638(Quinolinate phosphoribosyl transferase)|interpro:IPR004393(Nicotinate-nucleotide pyrophosphorylase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR022412|interpro:IPR027277|interpro:IPR036068|interpro:IPR037128|rcsb pdb:2JBM|rcsb pdb:4KWV|rcsb pdb:4KWW|rcsb pdb:5AYX|rcsb pdb:5AYY|rcsb pdb:5AYZ|reactome:R-HSA-196807 - - - figure legend:Fig 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:ayjZsjJprp+eirEIN5VqDHmIzoA9606 rigid:GJqe71bl5y5Hl12MEa6Kc5lU69w false sufficient binding region:711-828|myc tag:n-n green fluorescent protein tag:n-n - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9NZ94-2 uniprotkb:P68104 intact:EBI-16423037 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16424895|imex:IM-26157-179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Fig 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:2/pm0uiFKksVGTCswuMt30+c+T4 false sufficient binding region:711-828|myc tag:n-n green fluorescent protein tag:n-n - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9NZ94-2 uniprotkb:Q8IWB1 intact:EBI-16423037 intact:EBI-2556412|uniprotkb:Q5JU17|uniprotkb:Q96MS8|uniprotkb:Q9C0A9|uniprotkb:D3DRA5|ensembl:ENSP00000278071|ensembl:ENSP00000337178|ensembl:ENSP00000350915|ensembl:ENSP00000497746 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:ipri_human(display_long)|uniprotkb:DANGER(gene name synonym)|uniprotkb:KIAA1754(gene name synonym)|uniprotkb:Protein DANGER(gene name synonym)|uniprotkb:ITPRIP(gene name)|psi-mi:ITPRIP(display_short) psi-mi:"MI:0663"(confocal microscopy) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16424905|imex:IM-26157-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) refseq:NP_203755.1|ensembl:ENSG00000148841(gene)|ensembl:ENST00000278071(transcript)|ensembl:ENST00000337478(transcript)|ensembl:ENST00000358187(transcript)|ensembl:ENST00000647721(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR024797|interpro:IPR024810|interpro:IPR026250|refseq:NP_001258941.1|refseq:NP_001258942.1 - - - figure legend:Fig 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:wTUAsA+dqm1wkrs9z4E7a4PdcLk9606 rigid:Qg7lZWMJ0Ogfk/wXcJx6Z1cb0W4 false sufficient binding region:711-828|myc tag:n-n green fluorescent protein tag:n-n - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9NZ94-2 uniprotkb:P21333 intact:EBI-16423037 intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45 psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16424915|imex:IM-26157-155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N - - - figure legend:Fig 4Ai|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606 rigid:FKnNf/TzETGcNqND3ry8iGfQNYU false sufficient binding region:711-828|myc tag:n-n green fluorescent protein tag:n-n - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P00403 uniprotkb:Q9NZ94-2 intact:EBI-2105756|uniprotkb:Q37526|ensembl:ENSP00000354876 intact:EBI-16423037 psi-mi:cox2_human(display_long)|uniprotkb:MT-CO2(gene name)|psi-mi:MT-CO2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:COXII(gene name synonym)|uniprotkb:MTCO2(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:COX2(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0663"(confocal microscopy) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16424925|imex:IM-26157-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_003024029.1|ensembl:ENSG00000198712(gene)|ensembl:ENST00000361739(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00403|rcsb pdb:3VRJ|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - - - figure legend:Fig 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:NyMmciQe53E935KEZahz8cGPjIM9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:kmmfWUMSdAkbx/RcLUzTmYGBr6Q false green fluorescent protein tag:n-n sufficient binding region:711-828|myc tag:n-n - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:P05108 uniprotkb:Q9NZ94-2 intact:EBI-7183136|uniprotkb:Q8N1A7|uniprotkb:Q15081|intact:MINT-1200919|uniprotkb:Q16805|uniprotkb:A8K8D5|uniprotkb:B3KPU8|uniprotkb:G3XAD7|ensembl:ENSP00000268053|ensembl:ENSP00000500767 intact:EBI-16423037 psi-mi:cp11a_human(display_long)|uniprotkb:CYP11A1(gene name)|psi-mi:CYP11A1(display_short)|uniprotkb:CYP11A(gene name synonym)|uniprotkb:Cytochrome P450 11A1(gene name synonym)|uniprotkb:CYPXIA1(gene name synonym)|uniprotkb:Cholesterol desmolase(gene name synonym)|uniprotkb:"Cytochrome P450(scc)"(gene name synonym) psi-mi:q9nz94-2(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:HNL3(isoform synonym) psi-mi:"MI:0663"(confocal microscopy) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16424935|imex:IM-26157-157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093243.1|refseq:NP_000772.2|ensembl:ENSG00000140459(gene)|ensembl:ENSG00000288362(gene)|ensembl:ENST00000268053(transcript)|ensembl:ENST00000672385(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006700"(C21-steroid hormone biosynthetic process)|go:"GO:0006704"(glucocorticoid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008386"("cholesterol monooxygenase (side-chain-cleaving) activity")|go:"GO:0016125"(sterol metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0034650"(cortisol metabolic process)|go:"GO:0042359"(vitamin D metabolic process)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|interpro:IPR033283|interpro:IPR036396|mint:P05108|rcsb pdb:3N9Y|rcsb pdb:3N9Z|rcsb pdb:3NA0|rcsb pdb:3NA1|reactome:R-HSA-196108|reactome:R-HSA-211976|reactome:R-HSA-5579026 uniprotkb:Q9NZ94(isoform-parent)|uniprotkb:Q9NZ94-2(isoform-parent) - comment:mint|function:Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone|comment:homomint|function:"Defects in CYP11A1 are a cause of congenital adrenal insufficiency (CAI)"|function:"Defects in CYP11A1 are a cause of congenital lipoid adrenal hyperplasia (CLAH) [MIM:201710]; also called lipoid CAH. CLAH is the most severe form of adrenal hyperplasia. This autosomal recessive and potentially lethal condition includes the onset of profound adrenocortical insufficiency shortly after birth, hyperpigmentation reflecting increased production of pro-opiomelanocortin, elevated plasma renin activity as a consequence of reduced aldosterone synthesis, and male pseudohermaphroditism resulting from deficient fetal testicular testosterone synthesis. CLAH is a rare disease, except in Japan and Korea where it accounts for a significant percentage of cases of congenital adrenal hyperplasia" - figure legend:Fig 4Aii|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:I/jdJNWgdU7vLkY+5PwcsKUnBNI9606 rogid:zJAbB1paiNIkvVmQQT638+rczN49606 rigid:PN3EeV9/GpEnjOB7QksbsM9E+Nk false green fluorescent protein tag:n-n sufficient binding region:711-828|myc tag:n-n - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:P00403 uniprotkb:Q9NZ94 intact:EBI-2105756|uniprotkb:Q37526|ensembl:ENSP00000354876 intact:EBI-3920184|uniprotkb:Q9NZ95|uniprotkb:Q9NZ96|uniprotkb:D3DVV0|uniprotkb:Q9NZ97|uniprotkb:Q9P248|uniprotkb:Q8NCD0|ensembl:ENSP00000351591|uniprotkb:D3DVV1|uniprotkb:B2RBK1|uniprotkb:D2X2H6|uniprotkb:Q86V51 psi-mi:cox2_human(display_long)|uniprotkb:MT-CO2(gene name)|psi-mi:MT-CO2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:COXII(gene name synonym)|uniprotkb:MTCO2(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:COX2(gene name synonym) psi-mi:nlgn3_human(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:Gliotactin homolog(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16425019|imex:IM-26157-159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_003024029.1|ensembl:ENSG00000198712(gene)|ensembl:ENST00000361739(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00403|rcsb pdb:3VRJ|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 go:"GO:0098793"(presynapse)|refseq:NP_001160132.1|refseq:NP_061850.2|refseq:NP_851820.1|ensembl:ENSG00000196338(gene)|ensembl:ENST00000358741(transcript)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007612"(learning)|go:"GO:0009986"(cell surface)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030534"(adult behavior)|go:"GO:0035176"(social behavior)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048675"(axon extension)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060024"(rhythmic synaptic transmission)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0071625"(vocalization behavior)|go:"GO:0089717"(spanning component of membrane)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098985"(asymmetric, glutamatergic, excitatory synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR000460(Neuroligin)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR019819|interpro:IPR029058|interpro:IPR030024|mint:Q9NZ94|reactome:R-HSA-6794361|go:"GO:0098983"(symmetric, GABA-ergic, inhibitory synapse)|refseq:NP_001308205.1 - - - figure legend:Fig 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2017/09/21 2017/10/05 rogid:NyMmciQe53E935KEZahz8cGPjIM9606 rogid:OzGAr78JAaopeMCBpHnhVXP5DaU9606 rigid:z7hrFRGrjkbwBANU5H/sDYJ7NQ8 false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q9NZ94 uniprotkb:P21333 intact:EBI-3920184|uniprotkb:Q9NZ95|uniprotkb:Q9NZ96|uniprotkb:D3DVV0|uniprotkb:Q9NZ97|uniprotkb:Q9P248|uniprotkb:Q8NCD0|ensembl:ENSP00000351591|uniprotkb:D3DVV1|uniprotkb:B2RBK1|uniprotkb:D2X2H6|uniprotkb:Q86V51 intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45 psi-mi:nlgn3_human(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:Gliotactin homolog(gene name synonym) psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16425032|imex:IM-26157-239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0098793"(presynapse)|refseq:NP_001160132.1|refseq:NP_061850.2|refseq:NP_851820.1|ensembl:ENSG00000196338(gene)|ensembl:ENST00000358741(transcript)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007612"(learning)|go:"GO:0009986"(cell surface)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030534"(adult behavior)|go:"GO:0035176"(social behavior)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048675"(axon extension)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060024"(rhythmic synaptic transmission)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0071625"(vocalization behavior)|go:"GO:0089717"(spanning component of membrane)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098985"(asymmetric, glutamatergic, excitatory synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR000460(Neuroligin)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR019819|interpro:IPR029058|interpro:IPR030024|mint:Q9NZ94|reactome:R-HSA-6794361|go:"GO:0098983"(symmetric, GABA-ergic, inhibitory synapse)|refseq:NP_001308205.1 go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N - - - figure legend:Fig 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2017/09/21 2017/10/05 rogid:OzGAr78JAaopeMCBpHnhVXP5DaU9606 rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606 rigid:WbYigeCOleSlJkQfyrK+k9h4GUc false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q9NZ94 uniprotkb:P68104 intact:EBI-3920184|uniprotkb:Q9NZ95|uniprotkb:Q9NZ96|uniprotkb:D3DVV0|uniprotkb:Q9NZ97|uniprotkb:Q9P248|uniprotkb:Q8NCD0|ensembl:ENSP00000351591|uniprotkb:D3DVV1|uniprotkb:B2RBK1|uniprotkb:D2X2H6|uniprotkb:Q86V51 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:nlgn3_human(display_long)|uniprotkb:NLGN3(gene name)|psi-mi:NLGN3(display_short)|uniprotkb:KIAA1480(gene name synonym)|uniprotkb:NL3(gene name synonym)|uniprotkb:Gliotactin homolog(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Shen et al. (2015) pubmed:25464930|imex:IM-26157 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16425042|imex:IM-26157-119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0098793"(presynapse)|refseq:NP_001160132.1|refseq:NP_061850.2|refseq:NP_851820.1|ensembl:ENSG00000196338(gene)|ensembl:ENST00000358741(transcript)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007612"(learning)|go:"GO:0009986"(cell surface)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030534"(adult behavior)|go:"GO:0035176"(social behavior)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048675"(axon extension)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060024"(rhythmic synaptic transmission)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0071625"(vocalization behavior)|go:"GO:0089717"(spanning component of membrane)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098985"(asymmetric, glutamatergic, excitatory synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR000460(Neuroligin)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR019819|interpro:IPR029058|interpro:IPR030024|mint:Q9NZ94|reactome:R-HSA-6794361|go:"GO:0098983"(symmetric, GABA-ergic, inhibitory synapse)|refseq:NP_001308205.1 refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Fig 4Bi|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2017/09/21 2017/10/05 rogid:OzGAr78JAaopeMCBpHnhVXP5DaU9606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:osXyi6BiuuTO4eaEHrehu16Luok false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry)