#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q86YL7 uniprotkb:Q9P126-1 intact:EBI-723160|uniprotkb:O60836|uniprotkb:O95128|uniprotkb:Q7L375|uniprotkb:Q8NBQ8|uniprotkb:Q8NBR3|ensembl:ENSP00000478125|uniprotkb:B2R6J8|uniprotkb:A9Z1Y2|uniprotkb:E9PB68|uniprotkb:F6QWX5 intact:EBI-16130833|ensembl:ENSP00000298527 psi-mi:pdpn_human(display_long)|uniprotkb:Glycoprotein 36(gene name synonym)|uniprotkb:PA2.26 antigen(gene name synonym)|uniprotkb:T1-alpha(gene name synonym)|uniprotkb:Aggrus(gene name synonym)|uniprotkb:PDPN(gene name)|psi-mi:PDPN(display_short)|uniprotkb:GP36(gene name synonym)|uniprotkb:PSEC0003(orf name)|uniprotkb:PSEC0025(orf name) psi-mi:q9p126-1(display_long)|uniprotkb:CLEC1B(gene name)|psi-mi:CLEC1B(display_short)|uniprotkb:CLEC2(gene name synonym)|uniprotkb:UNQ721/PRO1384(orf name)|uniprotkb:C-type lectin-like receptor 2(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Nagae et al. (2014) pubmed:25458834|doi:10.1016/j.str.2014.09.009|imex:IM-24090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16130842|imex:IM-24090-1|dip:DIP-198480E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001006625.1|refseq:NP_001006626.1|refseq:NP_006465.3|refseq:NP_938203.2|go:"GO:0019956"(chemokine binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030168"(platelet activation)|go:"GO:0030175"(filopodium)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045121"(membrane raft)|go:"GO:0048535"(lymph node development)|go:"GO:0051087"(chaperone binding)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060838"(lymphatic endothelial cell fate commitment)|go:"GO:0061851"(leading edge of lamellipodium)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900024"(regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901731"(positive regulation of platelet aggregation)|go:"GO:1904328"(regulation of myofibroblast contraction)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0015884"(folic acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|rcsb pdb:4YO0|rcsb pdb:5XCV|rcsb pdb:7C94|rcsb pdb:7CQC|rcsb pdb:7CQD|reactome:R-HSA-114604|rcsb pdb:3WSR|ensembl:ENSG00000162493(gene)|ensembl:ENST00000621990(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001946"(lymphangiogenesis)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006833"(water transport)|refseq:XP_006710358.1|dip:DIP-61333N intact:EBI-748911(isoform-parent)|ensembl:ENSG00000165682(gene)|ensembl:ENST00000298527(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:rV+OkRMlmJb+XbE6bBaXubqccIU9606 rogid:em4Ssx8zZeXKwG+c5MGaNgR4W9Y9606 rigid:GqiLct+GGD3czSOkiUacFSgnNGY false O-glycosyl-L-threonine:52-52|sufficient binding region:38-54 sufficient binding region:96-221 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9P126-1 uniprotkb:Q9I841 intact:EBI-16130833|ensembl:ENSP00000298527 intact:EBI-9013678 psi-mi:q9p126-1(display_long)|uniprotkb:CLEC1B(gene name)|psi-mi:CLEC1B(display_short)|uniprotkb:CLEC2(gene name synonym)|uniprotkb:UNQ721/PRO1384(orf name)|uniprotkb:C-type lectin-like receptor 2(gene name synonym) psi-mi:slya_calrh(display_long)|uniprotkb:Aggretin alpha chain(gene name synonym)|uniprotkb:Rhodoaggretin subunit alpha(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Nagae et al. (2014) pubmed:25458834|doi:10.1016/j.str.2014.09.009|imex:IM-24090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:8717(calrh)|taxid:8717(Calloselasma rhodostoma) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16130866|imex:IM-24090-2|dip:DIP-198481E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-748911(isoform-parent)|ensembl:ENSG00000165682(gene)|ensembl:ENST00000298527(transcript) dip:DIP-61334N|go:"GO:0005576"(extracellular region)|go:"GO:0046872"(metal ion binding)|go:"GO:0060300"(regulation of cytokine activity)|go:"GO:0090729"(toxin activity)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|rcsb pdb:2VRP|rcsb pdb:3BX4|rcsb pdb:3WWK psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:em4Ssx8zZeXKwG+c5MGaNgR4W9Y9606 rogid:0zki8H5knSRRlBDzBailPhOoE8Q8717 rigid:3wCWBaNdKQaU0+BSEm3lntCsPzQ false sufficient binding region:96-221 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9P126-1 uniprotkb:Q9I840 intact:EBI-16130833|ensembl:ENSP00000298527 intact:EBI-9013681 psi-mi:q9p126-1(display_long)|uniprotkb:CLEC1B(gene name)|psi-mi:CLEC1B(display_short)|uniprotkb:CLEC2(gene name synonym)|uniprotkb:UNQ721/PRO1384(orf name)|uniprotkb:C-type lectin-like receptor 2(gene name synonym) psi-mi:slyb_calrh(display_long)|uniprotkb:Aggretin beta chain(gene name synonym)|uniprotkb:Rhodoaggretin subunit beta(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Nagae et al. (2014) pubmed:25458834|doi:10.1016/j.str.2014.09.009|imex:IM-24090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:8717(calrh)|taxid:8717(Calloselasma rhodostoma) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16130866|imex:IM-24090-2|dip:DIP-198481E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-748911(isoform-parent)|ensembl:ENSG00000165682(gene)|ensembl:ENST00000298527(transcript) dip:DIP-61335N|go:"GO:0005576"(extracellular region)|go:"GO:0046872"(metal ion binding)|go:"GO:0090729"(toxin activity)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|rcsb pdb:2VRP|rcsb pdb:3BX4|rcsb pdb:3WWK psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:em4Ssx8zZeXKwG+c5MGaNgR4W9Y9606 rogid:riCnnnpdeIfBlc/AE6XN1mKiGqo8717 rigid:3wCWBaNdKQaU0+BSEm3lntCsPzQ false sufficient binding region:96-221 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86YL7 uniprotkb:Q9P126-1 intact:EBI-723160|uniprotkb:O60836|uniprotkb:O95128|uniprotkb:Q7L375|uniprotkb:Q8NBQ8|uniprotkb:Q8NBR3|ensembl:ENSP00000478125|uniprotkb:B2R6J8|uniprotkb:A9Z1Y2|uniprotkb:E9PB68|uniprotkb:F6QWX5 intact:EBI-16130833|ensembl:ENSP00000298527 psi-mi:pdpn_human(display_long)|uniprotkb:Glycoprotein 36(gene name synonym)|uniprotkb:PA2.26 antigen(gene name synonym)|uniprotkb:T1-alpha(gene name synonym)|uniprotkb:Aggrus(gene name synonym)|uniprotkb:PDPN(gene name)|psi-mi:PDPN(display_short)|uniprotkb:GP36(gene name synonym)|uniprotkb:PSEC0003(orf name)|uniprotkb:PSEC0025(orf name) psi-mi:q9p126-1(display_long)|uniprotkb:CLEC1B(gene name)|psi-mi:CLEC1B(display_short)|uniprotkb:CLEC2(gene name synonym)|uniprotkb:UNQ721/PRO1384(orf name)|uniprotkb:C-type lectin-like receptor 2(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Nagae et al. (2014) pubmed:25458834|doi:10.1016/j.str.2014.09.009|imex:IM-24090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16130886|imex:IM-24090-3|dip:DIP-198480E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001006625.1|refseq:NP_001006626.1|refseq:NP_006465.3|refseq:NP_938203.2|go:"GO:0019956"(chemokine binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030168"(platelet activation)|go:"GO:0030175"(filopodium)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045121"(membrane raft)|go:"GO:0048535"(lymph node development)|go:"GO:0051087"(chaperone binding)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060838"(lymphatic endothelial cell fate commitment)|go:"GO:0061851"(leading edge of lamellipodium)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900024"(regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901731"(positive regulation of platelet aggregation)|go:"GO:1904328"(regulation of myofibroblast contraction)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0015884"(folic acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|rcsb pdb:4YO0|rcsb pdb:5XCV|rcsb pdb:7C94|rcsb pdb:7CQC|rcsb pdb:7CQD|reactome:R-HSA-114604|rcsb pdb:3WSR|ensembl:ENSG00000162493(gene)|ensembl:ENST00000621990(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001946"(lymphangiogenesis)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006833"(water transport)|refseq:XP_006710358.1|dip:DIP-61333N intact:EBI-748911(isoform-parent)|ensembl:ENSG00000165682(gene)|ensembl:ENST00000298527(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:rV+OkRMlmJb+XbE6bBaXubqccIU9606 rogid:em4Ssx8zZeXKwG+c5MGaNgR4W9Y9606 rigid:GqiLct+GGD3czSOkiUacFSgnNGY false O-glycosyl-L-threonine:52-52|sufficient binding region:38-54 sufficient binding region:96-221 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)