#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P10242 uniprotkb:P17542 intact:EBI-298355|uniprotkb:P78391|uniprotkb:P78392|uniprotkb:P78525|uniprotkb:P78526|uniprotkb:Q14023|uniprotkb:Q14024|uniprotkb:Q9UE83|uniprotkb:Q708E4|uniprotkb:Q708E7|ensembl:ENSP00000356788|uniprotkb:E9PNL6|uniprotkb:E9PI07|uniprotkb:E9PLZ5|uniprotkb:E9PNA4|uniprotkb:E9PRS2 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 psi-mi:myb_human(display_long)|uniprotkb:MYB(gene name)|psi-mi:MYB(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mansour et al. (2014) pubmed:25394790|doi:10.1126/science.1259037|imex:IM-24112 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16127555|imex:IM-24112-1|dip:DIP-198628E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155129.1|refseq:NP_001155130.1|refseq:NP_001155131.1|refseq:NP_001155132.1|refseq:NP_001123644.1|refseq:NP_001123645.1|refseq:NP_005366.2|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1904899"(positive regulation of hepatic stellate cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|mint:P10242|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000118513(gene)|ensembl:ENST00000367814(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|refseq:NP_001155128.1|dip:DIP-1057N refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:do/bvngcNTqnh1KZE4vDAtPP0749606 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 rigid:qNxZgiteFW9B7cSmbjZ8TWI3DWI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P10242 uniprotkb:P17542 intact:EBI-298355|uniprotkb:P78391|uniprotkb:P78392|uniprotkb:P78525|uniprotkb:P78526|uniprotkb:Q14023|uniprotkb:Q14024|uniprotkb:Q9UE83|uniprotkb:Q708E4|uniprotkb:Q708E7|ensembl:ENSP00000356788|uniprotkb:E9PNL6|uniprotkb:E9PI07|uniprotkb:E9PLZ5|uniprotkb:E9PNA4|uniprotkb:E9PRS2 intact:EBI-1753878|uniprotkb:D3DQ24|ensembl:ENSP00000294339|ensembl:ENSP00000360951 psi-mi:myb_human(display_long)|uniprotkb:MYB(gene name)|psi-mi:MYB(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:tal1_human(display_long)|uniprotkb:TAL1(gene name)|psi-mi:TAL1(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:TCL5(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 5(gene name synonym)|uniprotkb:BHLHA17(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 17(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mansour et al. (2014) pubmed:25394790|doi:10.1126/science.1259037|imex:IM-24112 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16127572|imex:IM-24112-2|dip:DIP-198628E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155129.1|refseq:NP_001155130.1|refseq:NP_001155131.1|refseq:NP_001155132.1|refseq:NP_001123644.1|refseq:NP_001123645.1|refseq:NP_005366.2|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1904899"(positive regulation of hepatic stellate cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|mint:P10242|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000118513(gene)|ensembl:ENST00000367814(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|refseq:NP_001155128.1|dip:DIP-1057N refseq:NP_003180.1|refseq:NP_001277332.1|refseq:NP_001277333.1|refseq:NP_001277334.1|refseq:XP_005271217.1|refseq:NP_001277335.1|refseq:NP_001274276.1|refseq:XP_016857676.1|refseq:XP_016857677.1|refseq:XP_016857678.1|refseq:XP_016857679.1|refseq:XP_016857680.1|dip:DIP-40640N|ensembl:ENSG00000162367(gene)|ensembl:ENST00000294339(transcript)|ensembl:ENST00000371884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|rcsb pdb:2YPA|rcsb pdb:2YPB|reactome:R-HSA-8939236|reactome:R-HSA-9616222|go:"GO:0000785"(chromatin) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/10 rogid:do/bvngcNTqnh1KZE4vDAtPP0749606 rogid:jLwUi22/Z+xOKRZsktn/yX6rRUo9606 rigid:qNxZgiteFW9B7cSmbjZ8TWI3DWI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)