#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P61077-1 uniprotkb:Q13490-1 intact:EBI-15567256|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|ensembl:ENSP00000378283|ensembl:ENSP00000396901 intact:EBI-16127374|ensembl:ENSP00000227758|ensembl:ENSP00000477613 psi-mi:p61077-1(display_long)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym) psi-mi:q13490-1(display_long)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym) psi-mi:"MI:0969"(bio-layer interferometry) Phillips et al. (2014) pubmed:25383668|doi:10.1038/nsmb.2916|imex:IM-24420 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16127388|imex:IM-24420-1|dip:DIP-199084E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|ensembl:ENSG00000109332(gene)|intact:EBI-348268(isoform-parent) intact:EBI-514538(isoform-parent)|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606 rogid:FOikzyDyDtlv2l69i/WNDNq674A9606 rigid:/5SmtBbH1It6NSgubYSC0i5+HEA false - sufficient binding region:373-618,266-362 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13490-1 uniprotkb:Q13490-1 intact:EBI-16127374|ensembl:ENSP00000227758|ensembl:ENSP00000477613 intact:EBI-16127374|ensembl:ENSP00000227758|ensembl:ENSP00000477613 psi-mi:q13490-1(display_long)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym) psi-mi:q13490-1(display_long)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym) psi-mi:"MI:0969"(bio-layer interferometry) Phillips et al. (2014) pubmed:25383668|doi:10.1038/nsmb.2916|imex:IM-24420 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16127408|imex:IM-24420-2|dip:DIP-66681E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-514538(isoform-parent)|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript) intact:EBI-514538(isoform-parent)|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:FOikzyDyDtlv2l69i/WNDNq674A9606 rogid:FOikzyDyDtlv2l69i/WNDNq674A9606 rigid:brQf3QtdM0hC+fOvM7TKcJjh/Uc false sufficient binding region:373-618,266-362 sufficient binding region:373-618,266-362 - 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q13490-1 uniprotkb:Q13490-1 intact:EBI-16127374|ensembl:ENSP00000227758|ensembl:ENSP00000477613 intact:EBI-16127374|ensembl:ENSP00000227758|ensembl:ENSP00000477613 psi-mi:q13490-1(display_long)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym) psi-mi:q13490-1(display_long)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Phillips et al. (2014) pubmed:25383668|doi:10.1038/nsmb.2916|imex:IM-24420 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16127427|imex:IM-24420-3|dip:DIP-66681E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-514538(isoform-parent)|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript) intact:EBI-514538(isoform-parent)|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:FOikzyDyDtlv2l69i/WNDNq674A9606 rogid:FOikzyDyDtlv2l69i/WNDNq674A9606 rigid:brQf3QtdM0hC+fOvM7TKcJjh/Uc false sufficient binding region:373-618,266-362 sufficient binding region:373-618,266-362 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-4399559 uniprotkb:Q13490-1 dip:DIP-24261N intact:EBI-16127374|ensembl:ENSP00000227758|ensembl:ENSP00000477613 psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:q13490-1(display_long)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym) psi-mi:"MI:0969"(bio-layer interferometry) Phillips et al. (2014) pubmed:25383668|doi:10.1038/nsmb.2916|imex:IM-24420 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16127446|imex:IM-24420-4|dip:DIP-199085E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 intact:EBI-514538(isoform-parent)|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript) psi-mi:"MI:0465"(dip) no-uniprot-update: - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/15 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rogid:FOikzyDyDtlv2l69i/WNDNq674A9606 rigid:X4/quj+xUA0cIrv/5QI27f1snqo false - sufficient binding region:373-618,266-362|mutation disrupting interaction strength:404-404,402-402 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13490-1 uniprotkb:Q13490-1 intact:EBI-16127374|ensembl:ENSP00000227758|ensembl:ENSP00000477613 intact:EBI-16127374|ensembl:ENSP00000227758|ensembl:ENSP00000477613 psi-mi:q13490-1(display_long)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym) psi-mi:q13490-1(display_long)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym) psi-mi:"MI:0826"(x ray scattering) Phillips et al. (2014) pubmed:25383668|doi:10.1038/nsmb.2916|imex:IM-24420 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16127470|imex:IM-24420-5|dip:DIP-66681E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-514538(isoform-parent)|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript) intact:EBI-514538(isoform-parent)|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:FOikzyDyDtlv2l69i/WNDNq674A9606 rogid:FOikzyDyDtlv2l69i/WNDNq674A9606 rigid:brQf3QtdM0hC+fOvM7TKcJjh/Uc false sufficient binding region:373-618,266-362 sufficient binding region:373-618,266-362 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13490-1 uniprotkb:Q13490-1 intact:EBI-16127374|ensembl:ENSP00000227758|ensembl:ENSP00000477613 intact:EBI-16127374|ensembl:ENSP00000227758|ensembl:ENSP00000477613 psi-mi:q13490-1(display_long)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym) psi-mi:q13490-1(display_long)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym) psi-mi:"MI:0067"(light scattering) Phillips et al. (2014) pubmed:25383668|doi:10.1038/nsmb.2916|imex:IM-24420 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16127489|imex:IM-24420-6|dip:DIP-66681E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-514538(isoform-parent)|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript) intact:EBI-514538(isoform-parent)|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:FOikzyDyDtlv2l69i/WNDNq674A9606 rogid:FOikzyDyDtlv2l69i/WNDNq674A9606 rigid:brQf3QtdM0hC+fOvM7TKcJjh/Uc false sufficient binding region:373-618,266-362 sufficient binding region:373-618,266-362 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)