#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P68135	uniprotkb:Q06440	intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020	intact:EBI-4950|uniprotkb:D6VZ64|ensemblfungi:YLR429W	psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:coro_yeast(display_long)|uniprotkb:CRN1(gene name)|psi-mi:CRN1(display_short)|uniprotkb:L9576.2(orf name)|uniprotkb:YLR429W(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Ge et al. (2014)	pubmed:25362487|doi:10.1038/nsmb.2907|imex:IM-24417	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16125754|imex:IM-24417-1|dip:DIP-199080E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N	refseq:NP_013533.1|sgd:S000004421|ensemblfungi:YLR429W(gene)|dip:DIP-2722N|mint:Q06440|ensemblfungi:YLR429W_mRNA(transcript)|go:"GO:0007015"(actin filament organization)|go:"GO:0007017"(microtubule-based process)|go:"GO:0008017"(microtubule binding)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322	psi-mi:"MI:0465"(dip)	-	crc64:E4A3AC8CF5112001	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986	rogid:JlhPXlLFQiSbokXWg1RUSHYrDIA559292	rigid:CkxJ3vAQevXSROeVQlBelr5MTI8	false	-	sufficient binding region:1-600	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P60010	uniprotkb:Q06440	intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C	intact:EBI-4950|uniprotkb:D6VZ64|ensemblfungi:YLR429W	psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name)	psi-mi:coro_yeast(display_long)|uniprotkb:CRN1(gene name)|psi-mi:CRN1(display_short)|uniprotkb:L9576.2(orf name)|uniprotkb:YLR429W(locus name)	psi-mi:"MI:0030"(cross-linking study)	Ge et al. (2014)	pubmed:25362487|doi:10.1038/nsmb.2907|imex:IM-24417	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16125792|imex:IM-24417-3|dip:DIP-92675E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026	refseq:NP_013533.1|sgd:S000004421|ensemblfungi:YLR429W(gene)|dip:DIP-2722N|mint:Q06440|ensemblfungi:YLR429W_mRNA(transcript)|go:"GO:0007015"(actin filament organization)|go:"GO:0007017"(microtubule-based process)|go:"GO:0008017"(microtubule binding)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322	psi-mi:"MI:0465"(dip)	crc64:87AC19B0B0BC9E71	crc64:E4A3AC8CF5112001	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292	rogid:JlhPXlLFQiSbokXWg1RUSHYrDIA559292	rigid:1HgVEmrlzMIju4UgLzqSXMOs7wE	false	-	sufficient binding region:1-600	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68135	uniprotkb:Q06440	intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020	intact:EBI-4950|uniprotkb:D6VZ64|ensemblfungi:YLR429W	psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:coro_yeast(display_long)|uniprotkb:CRN1(gene name)|psi-mi:CRN1(display_short)|uniprotkb:L9576.2(orf name)|uniprotkb:YLR429W(locus name)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Ge et al. (2014)	pubmed:25362487|doi:10.1038/nsmb.2907|imex:IM-24417	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16125811|imex:IM-24417-4|dip:DIP-199080E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N	refseq:NP_013533.1|sgd:S000004421|ensemblfungi:YLR429W(gene)|dip:DIP-2722N|mint:Q06440|ensemblfungi:YLR429W_mRNA(transcript)|go:"GO:0007015"(actin filament organization)|go:"GO:0007017"(microtubule-based process)|go:"GO:0008017"(microtubule binding)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322	psi-mi:"MI:0465"(dip)	-	crc64:E4A3AC8CF5112001	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986	rogid:JlhPXlLFQiSbokXWg1RUSHYrDIA559292	rigid:CkxJ3vAQevXSROeVQlBelr5MTI8	false	acrylodan label:376-376	sufficient binding region:1-600	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P60010	uniprotkb:Q06440	intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C	intact:EBI-4950|uniprotkb:D6VZ64|ensemblfungi:YLR429W	psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name)	psi-mi:coro_yeast(display_long)|uniprotkb:CRN1(gene name)|psi-mi:CRN1(display_short)|uniprotkb:L9576.2(orf name)|uniprotkb:YLR429W(locus name)	psi-mi:"MI:0028"(cosedimentation in solution)	Ge et al. (2014)	pubmed:25362487|doi:10.1038/nsmb.2907|imex:IM-24417	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16125773|imex:IM-24417-2|dip:DIP-92675E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026	refseq:NP_013533.1|sgd:S000004421|ensemblfungi:YLR429W(gene)|dip:DIP-2722N|mint:Q06440|ensemblfungi:YLR429W_mRNA(transcript)|go:"GO:0007015"(actin filament organization)|go:"GO:0007017"(microtubule-based process)|go:"GO:0008017"(microtubule binding)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322	psi-mi:"MI:0465"(dip)	crc64:87AC19B0B0BC9E71	crc64:E4A3AC8CF5112001	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292	rogid:JlhPXlLFQiSbokXWg1RUSHYrDIA559292	rigid:1HgVEmrlzMIju4UgLzqSXMOs7wE	false	-	sufficient binding region:1-600	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P68135	uniprotkb:Q06440	intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020	intact:EBI-4950|uniprotkb:D6VZ64|ensemblfungi:YLR429W	psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:coro_yeast(display_long)|uniprotkb:CRN1(gene name)|psi-mi:CRN1(display_short)|uniprotkb:L9576.2(orf name)|uniprotkb:YLR429W(locus name)	psi-mi:"MI:0030"(cross-linking study)	Ge et al. (2014)	pubmed:25362487|doi:10.1038/nsmb.2907|imex:IM-24417	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16125832|imex:IM-24417-5|dip:DIP-199080E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N	refseq:NP_013533.1|sgd:S000004421|ensemblfungi:YLR429W(gene)|dip:DIP-2722N|mint:Q06440|ensemblfungi:YLR429W_mRNA(transcript)|go:"GO:0007015"(actin filament organization)|go:"GO:0007017"(microtubule-based process)|go:"GO:0008017"(microtubule binding)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322	psi-mi:"MI:0465"(dip)	-	crc64:E4A3AC8CF5112001	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986	rogid:JlhPXlLFQiSbokXWg1RUSHYrDIA559292	rigid:CkxJ3vAQevXSROeVQlBelr5MTI8	false	-	sufficient binding region:1-600	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)