#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UGM1 uniprotkb:Q9UGM1 intact:EBI-9008641|uniprotkb:Q4W5A2|uniprotkb:Q9NYV2|uniprotkb:Q14CY7|ensembl:ENSP00000312663 intact:EBI-9008641|uniprotkb:Q4W5A2|uniprotkb:Q9NYV2|uniprotkb:Q14CY7|ensembl:ENSP00000312663 psi-mi:acha9_human(display_long)|uniprotkb:CHRNA9(gene name)|psi-mi:CHRNA9(display_short)|uniprotkb:NACHRA9(gene name synonym)|uniprotkb:Nicotinic acetylcholine receptor subunit alpha-9(gene name synonym) psi-mi:acha9_human(display_long)|uniprotkb:CHRNA9(gene name)|psi-mi:CHRNA9(display_short)|uniprotkb:NACHRA9(gene name synonym)|uniprotkb:Nicotinic acetylcholine receptor subunit alpha-9(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Zouridakis et al. (2014) pubmed:25282151|doi:10.1038/nsmb.2900|imex:IM-23342 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16123240|imex:IM-23342-1|dip:DIP-197294E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61053N|refseq:NP_060051.2|ensembl:ENSG00000174343(gene)|ensembl:ENST00000310169(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036734|rcsb pdb:4D01|rcsb pdb:4UXU|rcsb pdb:4UY2|rcsb pdb:6HY7|reactome:R-HSA-629594|reactome:R-HSA-9667769|interpro:IPR036719 dip:DIP-61053N|refseq:NP_060051.2|ensembl:ENSG00000174343(gene)|ensembl:ENST00000310169(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036734|rcsb pdb:4D01|rcsb pdb:4UXU|rcsb pdb:4UY2|rcsb pdb:6HY7|reactome:R-HSA-629594|reactome:R-HSA-9667769|interpro:IPR036719 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4922(picpa)|taxid:4922("Pichia pastoris (Yeast)") - 2017/08/08 2017/08/10 rogid:sLAFAVDF+jBxk6zIiZftuuvJt8M9606 rogid:sLAFAVDF+jBxk6zIiZftuuvJt8M9606 rigid:nfupkBr4Kz0FMvpliRkhFnPfm88 false sufficient binding region:26-237 sufficient binding region:26-237 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60616 uniprotkb:Q9UGM1 intact:EBI-16123259|uniprotkb:P01378|uniprotkb:Q90WK0|uniprotkb:Q9PRI7|uniprotkb:Q9W726|uniprotkb:Q9W797|uniprotkb:Q9YI08 intact:EBI-9008641|uniprotkb:Q4W5A2|uniprotkb:Q9NYV2|uniprotkb:Q14CY7|ensembl:ENSP00000312663 psi-mi:3l21v_bunmu(display_long)|uniprotkb:Long neurotoxin 1(gene name synonym) psi-mi:acha9_human(display_long)|uniprotkb:CHRNA9(gene name)|psi-mi:CHRNA9(display_short)|uniprotkb:NACHRA9(gene name synonym)|uniprotkb:Nicotinic acetylcholine receptor subunit alpha-9(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Zouridakis et al. (2014) pubmed:25282151|doi:10.1038/nsmb.2900|imex:IM-23342 taxid:8616(bunmu)|taxid:8616(Bungarus multicinctus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16123280|imex:IM-23342-2|dip:DIP-197295E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005576"(extracellular region)|go:"GO:0090729"(toxin activity)|interpro:IPR003571(Snake toxin)|interpro:IPR018354|interpro:IPR035076|rcsb pdb:1HC9|rcsb pdb:2QC1|rcsb pdb:4HQP|rcsb pdb:4UY2|rcsb pdb:5HBT|rcsb pdb:5HBV|rcsb pdb:7KOO|dip:DIP-61054N dip:DIP-61053N|refseq:NP_060051.2|ensembl:ENSG00000174343(gene)|ensembl:ENST00000310169(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036734|rcsb pdb:4D01|rcsb pdb:4UXU|rcsb pdb:4UY2|rcsb pdb:6HY7|reactome:R-HSA-629594|reactome:R-HSA-9667769|interpro:IPR036719 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:ClFuTvYDaPKxcou61uyU28GyY888616 rogid:sLAFAVDF+jBxk6zIiZftuuvJt8M9606 rigid:k9WiHQA/22jZRNUpFvVQ3D0G+TQ false sufficient binding region:22-95 sufficient binding region:26-237 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60616 uniprotkb:Q9UGM1 intact:EBI-16123259|uniprotkb:P01378|uniprotkb:Q90WK0|uniprotkb:Q9PRI7|uniprotkb:Q9W726|uniprotkb:Q9W797|uniprotkb:Q9YI08 intact:EBI-9008641|uniprotkb:Q4W5A2|uniprotkb:Q9NYV2|uniprotkb:Q14CY7|ensembl:ENSP00000312663 psi-mi:3l21v_bunmu(display_long)|uniprotkb:Long neurotoxin 1(gene name synonym) psi-mi:acha9_human(display_long)|uniprotkb:CHRNA9(gene name)|psi-mi:CHRNA9(display_short)|uniprotkb:NACHRA9(gene name synonym)|uniprotkb:Nicotinic acetylcholine receptor subunit alpha-9(gene name synonym) psi-mi:"MI:0096"(pull down) Zouridakis et al. (2014) pubmed:25282151|doi:10.1038/nsmb.2900|imex:IM-23342 taxid:8616(bunmu)|taxid:8616(Bungarus multicinctus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16123301|imex:IM-23342-3|dip:DIP-197295E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005576"(extracellular region)|go:"GO:0090729"(toxin activity)|interpro:IPR003571(Snake toxin)|interpro:IPR018354|interpro:IPR035076|rcsb pdb:1HC9|rcsb pdb:2QC1|rcsb pdb:4HQP|rcsb pdb:4UY2|rcsb pdb:5HBT|rcsb pdb:5HBV|rcsb pdb:7KOO|dip:DIP-61054N dip:DIP-61053N|refseq:NP_060051.2|ensembl:ENSG00000174343(gene)|ensembl:ENST00000310169(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036734|rcsb pdb:4D01|rcsb pdb:4UXU|rcsb pdb:4UY2|rcsb pdb:6HY7|reactome:R-HSA-629594|reactome:R-HSA-9667769|interpro:IPR036719 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:ClFuTvYDaPKxcou61uyU28GyY888616 rogid:sLAFAVDF+jBxk6zIiZftuuvJt8M9606 rigid:k9WiHQA/22jZRNUpFvVQ3D0G+TQ false sufficient binding region:22-95|125i radiolabel:?-? sufficient binding region:26-237|his tag:c-c - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography)