#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:37396"	uniprotkb:P35728	intact:EBI-13940676|chebi:"CHEBI:26351"|chebi:"CHEBI:8582"	intact:EBI-26710|uniprotkb:D6VXM8|ensemblfungi:YKL059C	psi-mi:proteoglycan(display_short)|psi-mi:"CHEBI:37396"(display_long)|intact:Proteoglycan(synonym)|intact:proteoglycans(iupac name)	psi-mi:mpe1_yeast(display_long)|uniprotkb:YKL316(orf name)|uniprotkb:YKL059C(locus name)|uniprotkb:MPE1(gene name)|psi-mi:MPE1(display_short)	psi-mi:"MI:0096"(pull down)	Lee et al. (2014)	pubmed:25135474|imex:IM-25682	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13939824|imex:IM-25682-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_012864.1|sgd:S000001542|mint:P35728|dip:DIP-6650N|ensemblfungi:YKL059C(gene)|ensemblfungi:YKL059C_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014891(DWNN domain)|interpro:IPR033489|interpro:IPR036875|rcsb pdb:6I1D|reactome:R-SCE-983168	-	-	crc64:487567F6FD2C3F61	figure legend:Fig. 3A, Supp. Fig. 2A|comment:Interactions of Mpe1 with other processing complex  subunits are not mediated by RNA.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/02/27	2017/03/01	-	rogid:aR+VKZaKRew+nk35PgGp40lkCU4559292	-	false	DNA chemical modification:?-?("CHEBI:89552")	myc tag:n-n|his tag:c-c|sufficient binding region:1-282	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35728	uniprotkb:Q06224	intact:EBI-26710|uniprotkb:D6VXM8|ensemblfungi:YKL059C	intact:EBI-38345|uniprotkb:D6VYS4|ensemblfungi:YLR277C	psi-mi:mpe1_yeast(display_long)|uniprotkb:YKL316(orf name)|uniprotkb:YKL059C(locus name)|uniprotkb:MPE1(gene name)|psi-mi:MPE1(display_short)	psi-mi:ysh1_yeast(display_long)|uniprotkb:YSH1(gene name)|psi-mi:YSH1(display_short)|uniprotkb:BRR5(gene name synonym)|uniprotkb:Yeast 73 kDa homolog 1(gene name synonym)|uniprotkb:YLR277C(locus name)|uniprotkb:mRNA 3'-end-processing protein YSH1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lee et al. (2014)	pubmed:25135474|imex:IM-25682	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13939824|imex:IM-25682-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012864.1|sgd:S000001542|mint:P35728|dip:DIP-6650N|ensemblfungi:YKL059C(gene)|ensemblfungi:YKL059C_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014891(DWNN domain)|interpro:IPR033489|interpro:IPR036875|rcsb pdb:6I1D|reactome:R-SCE-983168	refseq:NP_013379.1|sgd:S000004267|mint:Q06224|dip:DIP-2470N|ensemblfungi:YLR277C(gene)|ensemblfungi:YLR277C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|rcsb pdb:6I1D|reactome:R-SCE-77595	-	crc64:487567F6FD2C3F61	crc64:901582F0C33AD6F7	figure legend:Fig. 3A, Supp. Fig. 2A|comment:Interactions of Mpe1 with other processing complex  subunits are not mediated by RNA.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/02/27	2017/03/01	rogid:aR+VKZaKRew+nk35PgGp40lkCU4559292	rogid:hzM2FredjCDlhdDUSIwMuLop/DU559292	-	false	myc tag:n-n|his tag:c-c|sufficient binding region:1-282	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35728	uniprotkb:Q01329	intact:EBI-26710|uniprotkb:D6VXM8|ensemblfungi:YKL059C	intact:EBI-14145|ensemblfungi:YAL043C|uniprotkb:D6VPH3	psi-mi:mpe1_yeast(display_long)|uniprotkb:YKL316(orf name)|uniprotkb:YKL059C(locus name)|uniprotkb:MPE1(gene name)|psi-mi:MPE1(display_short)	psi-mi:pta1_yeast(display_long)|uniprotkb:PTA1(gene name)|psi-mi:PTA1(display_short)|uniprotkb:FUN39(orf name)|uniprotkb:YAL043C(locus name)	psi-mi:"MI:0096"(pull down)	Lee et al. (2014)	pubmed:25135474|imex:IM-25682	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13939824|imex:IM-25682-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012864.1|sgd:S000001542|mint:P35728|dip:DIP-6650N|ensemblfungi:YKL059C(gene)|ensemblfungi:YKL059C_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014891(DWNN domain)|interpro:IPR033489|interpro:IPR036875|rcsb pdb:6I1D|reactome:R-SCE-983168	go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0030846"("termination of RNA polymerase II transcription, poly(A)-coupled")|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR021850|interpro:IPR032460|reactome:R-SCE-77595|ensemblfungi:YAL043C(gene)|ensemblfungi:YAL043C_mRNA(transcript)|refseq:NP_009356.1|sgd:S000000041|mint:Q01329|dip:DIP-2469N	-	crc64:487567F6FD2C3F61	crc64:E2AB1F468B7BC8D0	figure legend:Fig. 3A, Supp. Fig. 2A|comment:Interactions of Mpe1 with other processing complex  subunits are not mediated by RNA.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/02/27	2017/03/01	rogid:aR+VKZaKRew+nk35PgGp40lkCU4559292	rogid:Ns52iFCWTTfI6FAlDloej5RadO8559292	-	false	myc tag:n-n|his tag:c-c|sufficient binding region:1-282	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35728	uniprotkb:P29468	intact:EBI-26710|uniprotkb:D6VXM8|ensemblfungi:YKL059C	intact:EBI-12917|uniprotkb:D6VXT8|ensemblfungi:YKR002W	psi-mi:mpe1_yeast(display_long)|uniprotkb:YKL316(orf name)|uniprotkb:YKL059C(locus name)|uniprotkb:MPE1(gene name)|psi-mi:MPE1(display_short)	psi-mi:pap_yeast(display_long)|uniprotkb:YKR002W(locus name)|uniprotkb:PAP1(gene name)|psi-mi:PAP1(display_short)|uniprotkb:Polynucleotide adenylyltransferase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lee et al. (2014)	pubmed:25135474|imex:IM-25682	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13939824|imex:IM-25682-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012864.1|sgd:S000001542|mint:P35728|dip:DIP-6650N|ensemblfungi:YKL059C(gene)|ensemblfungi:YKL059C_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014891(DWNN domain)|interpro:IPR033489|interpro:IPR036875|rcsb pdb:6I1D|reactome:R-SCE-983168	sgd:S000001710|ensemblfungi:YKR002W(gene)|ensemblfungi:YKR002W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0043631"(RNA polyadenylation)|go:"GO:0071050"("sno(s)RNA polyadenylation")|interpro:IPR007010("Poly(A) polymerase, RNA-binding region")|interpro:IPR007012("Poly(A) polymerase, central region")|interpro:IPR011068(Nucleotidyltransferase, class I, C-terminal-like)|interpro:IPR014492("Poly(A) polymerase")|interpro:IPR043519|rcsb pdb:1FA0|rcsb pdb:2HHP|interpro:IPR002934(Nucleotidyltransferase)|rcsb pdb:2O1P|rcsb pdb:2Q66|rcsb pdb:3C66|refseq:NP_012927.3|mint:P29468|dip:DIP-2297N	-	crc64:487567F6FD2C3F61	crc64:759DE5210DC8D881	figure legend:Fig. 3A, Supp. Fig. 2A|comment:Interactions of Mpe1 with other processing complex  subunits are not mediated by RNA.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/02/27	2017/03/01	rogid:aR+VKZaKRew+nk35PgGp40lkCU4559292	rogid:fqzEpPcHkyfB6yydoLTsaCxWOqo559292	-	false	myc tag:n-n|his tag:c-c|sufficient binding region:1-282	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35728	uniprotkb:P25299	intact:EBI-26710|uniprotkb:D6VXM8|ensemblfungi:YKL059C	intact:EBI-15640|uniprotkb:D6VU95|ensemblfungi:YGL044C	psi-mi:mpe1_yeast(display_long)|uniprotkb:YKL316(orf name)|uniprotkb:YKL059C(locus name)|uniprotkb:MPE1(gene name)|psi-mi:MPE1(display_short)	psi-mi:rna15_yeast(display_long)|uniprotkb:YGL044C(locus name)|uniprotkb:RNA15(gene name)|psi-mi:RNA15(display_short)	psi-mi:"MI:0096"(pull down)	Lee et al. (2014)	pubmed:25135474|imex:IM-25682	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13939824|imex:IM-25682-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012864.1|sgd:S000001542|mint:P35728|dip:DIP-6650N|ensemblfungi:YKL059C(gene)|ensemblfungi:YKL059C_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014891(DWNN domain)|interpro:IPR033489|interpro:IPR036875|rcsb pdb:6I1D|reactome:R-SCE-983168	refseq:NP_011471.1|sgd:S000003012|ensemblfungi:YGL044C(gene)|ensemblfungi:YGL044C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR026896|interpro:IPR035979|interpro:IPR038192|rcsb pdb:2KM8|rcsb pdb:2L9B|rcsb pdb:2X1A|rcsb pdb:2X1B|rcsb pdb:2X1F|dip:DIP-1489N|mint:P25299	-	crc64:487567F6FD2C3F61	crc64:10053B8648A71ECB	figure legend:Fig. 3A, Supp. Fig. 2A|comment:Interactions of Mpe1 with other processing complex  subunits are not mediated by RNA.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/02/27	2017/03/01	rogid:aR+VKZaKRew+nk35PgGp40lkCU4559292	rogid:TqfxsTHAh9CPJJ6Q7uH6kz988hk559292	-	false	myc tag:n-n|his tag:c-c|sufficient binding region:1-282	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35728	uniprotkb:P25298	intact:EBI-26710|uniprotkb:D6VXM8|ensemblfungi:YKL059C	intact:EBI-15632|uniprotkb:D6VZN5|ensemblfungi:YMR061W	psi-mi:mpe1_yeast(display_long)|uniprotkb:YKL316(orf name)|uniprotkb:YKL059C(locus name)|uniprotkb:MPE1(gene name)|psi-mi:MPE1(display_short)	psi-mi:rna14_yeast(display_long)|uniprotkb:YM9796.14(orf name)|uniprotkb:YMR061W(locus name)|uniprotkb:RNA14(gene name)|psi-mi:RNA14(display_short)	psi-mi:"MI:0096"(pull down)	Lee et al. (2014)	pubmed:25135474|imex:IM-25682	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13939824|imex:IM-25682-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012864.1|sgd:S000001542|mint:P35728|dip:DIP-6650N|ensemblfungi:YKL059C(gene)|ensemblfungi:YKL059C_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014891(DWNN domain)|interpro:IPR033489|interpro:IPR036875|rcsb pdb:6I1D|reactome:R-SCE-983168	refseq:NP_013777.1|sgd:S000004665|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR008847(Suppressor of forked)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:2L9B|ensemblfungi:YMR061W(gene)|ensemblfungi:YMR061W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0031123"(RNA 3'-end processing)|dip:DIP-1488N|mint:P25298	-	crc64:487567F6FD2C3F61	crc64:102433295FE7CD63	figure legend:Fig. 3A, Supp. Fig. 2A|comment:Interactions of Mpe1 with other processing complex  subunits are not mediated by RNA.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/02/27	2017/03/01	rogid:aR+VKZaKRew+nk35PgGp40lkCU4559292	rogid:Ful6ie8/P/XQWsmSjGP4HMQLFgE559292	-	false	myc tag:n-n|his tag:c-c|sufficient binding region:1-282	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35728	uniprotkb:Q06632	intact:EBI-26710|uniprotkb:D6VXM8|ensemblfungi:YKL059C	intact:EBI-32872|uniprotkb:D6VST0|ensemblfungi:YDR301W	psi-mi:mpe1_yeast(display_long)|uniprotkb:YKL316(orf name)|uniprotkb:YKL059C(locus name)|uniprotkb:MPE1(gene name)|psi-mi:MPE1(display_short)	psi-mi:cft1_yeast(display_long)|uniprotkb:CFT1(gene name)|psi-mi:CFT1(display_short)|uniprotkb:Cleavage factor two protein 1(gene name synonym)|uniprotkb:YHH1(gene name synonym)|uniprotkb:YDR301W(locus name)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (2014)	pubmed:25135474|imex:IM-25682	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13939883|imex:IM-25682-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012864.1|sgd:S000001542|mint:P35728|dip:DIP-6650N|ensemblfungi:YKL059C(gene)|ensemblfungi:YKL059C_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014891(DWNN domain)|interpro:IPR033489|interpro:IPR036875|rcsb pdb:6I1D|reactome:R-SCE-983168	refseq:NP_010587.1|sgd:S000002709|mint:Q06632|dip:DIP-2467N|ensemblfungi:YDR301W(gene)|ensemblfungi:YDR301W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:6EOJ|reactome:R-SCE-77595	-	crc64:487567F6FD2C3F61	crc64:BC50D3770E9E758E	figure legend:Fig 3B, 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/02/27	2017/02/27	rogid:aR+VKZaKRew+nk35PgGp40lkCU4559292	rogid:w7ihQWzFy4re0RY6pDGFYCs29+8559292	rigid:xORPXF5lvdW3dblcQyeo2xAyhrA	false	sufficient binding region:174-282	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53538	uniprotkb:Q01329	intact:EBI-18134|uniprotkb:D6W0W8|uniprotkb:Q6Q569|ensemblfungi:YNL222W	intact:EBI-14145|ensemblfungi:YAL043C|uniprotkb:D6VPH3	psi-mi:ssu72_yeast(display_long)|uniprotkb:SSU72(gene name)|psi-mi:SSU72(display_short)|uniprotkb:YNL222W(locus name)|uniprotkb:N1279(orf name)|uniprotkb:Suppressor of SUA7 protein 2(gene name synonym)	psi-mi:pta1_yeast(display_long)|uniprotkb:PTA1(gene name)|psi-mi:PTA1(display_short)|uniprotkb:FUN39(orf name)|uniprotkb:YAL043C(locus name)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (2014)	pubmed:25135474|imex:IM-25682	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13939934|imex:IM-25682-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014177.1|sgd:S000005166|ensemblfungi:YNL222W(gene)|ensemblfungi:YNL222W_mRNA(transcript)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009302"("sno(s)RNA transcription")|go:"GO:0030846"("termination of RNA polymerase II transcription, poly(A)-coupled")|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031564"(transcription antitermination)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR006811(Ssu72-like protein)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|dip:DIP-6700N|mint:P53538	go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0030846"("termination of RNA polymerase II transcription, poly(A)-coupled")|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR021850|interpro:IPR032460|reactome:R-SCE-77595|ensemblfungi:YAL043C(gene)|ensemblfungi:YAL043C_mRNA(transcript)|refseq:NP_009356.1|sgd:S000000041|mint:Q01329|dip:DIP-2469N	-	crc64:1AE1B29B87C82FE9	crc64:E2AB1F468B7BC8D0	figure legend:Fig 3B, 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/02/27	2017/02/27	rogid:RVkI+vIe4QobtIZ0xqEK/F5DEsM559292	rogid:Ns52iFCWTTfI6FAlDloej5RadO8559292	rigid:7aoKBZ/mqRAdAVFvsGGkiNxqjp0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06632	uniprotkb:P35728	intact:EBI-32872|uniprotkb:D6VST0|ensemblfungi:YDR301W	intact:EBI-26710|uniprotkb:D6VXM8|ensemblfungi:YKL059C	psi-mi:cft1_yeast(display_long)|uniprotkb:CFT1(gene name)|psi-mi:CFT1(display_short)|uniprotkb:Cleavage factor two protein 1(gene name synonym)|uniprotkb:YHH1(gene name synonym)|uniprotkb:YDR301W(locus name)	psi-mi:mpe1_yeast(display_long)|uniprotkb:YKL316(orf name)|uniprotkb:YKL059C(locus name)|uniprotkb:MPE1(gene name)|psi-mi:MPE1(display_short)	psi-mi:"MI:0096"(pull down)	Lee et al. (2014)	pubmed:25135474|imex:IM-25682	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13940008|imex:IM-25682-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010587.1|sgd:S000002709|mint:Q06632|dip:DIP-2467N|ensemblfungi:YDR301W(gene)|ensemblfungi:YDR301W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:6EOJ|reactome:R-SCE-77595	refseq:NP_012864.1|sgd:S000001542|mint:P35728|dip:DIP-6650N|ensemblfungi:YKL059C(gene)|ensemblfungi:YKL059C_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014891(DWNN domain)|interpro:IPR033489|interpro:IPR036875|rcsb pdb:6I1D|reactome:R-SCE-983168	-	crc64:BC50D3770E9E758E	crc64:487567F6FD2C3F61	figure legend:Fig 3E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/27	2017/02/27	rogid:w7ihQWzFy4re0RY6pDGFYCs29+8559292	rogid:aR+VKZaKRew+nk35PgGp40lkCU4559292	rigid:xORPXF5lvdW3dblcQyeo2xAyhrA	false	35s radiolabel:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)