#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P76632 uniprotkb:Q46897 intact:EBI-1125571|uniprotkb:Q2MA70|uniprotkb:Q46900|ensemblbacteria:AAC75801|ensemblbacteria:BAE76836 intact:EBI-1130217|uniprotkb:Q2MA73|ensemblbacteria:AAC75798|ensemblbacteria:BAE76833 psi-mi:cse2_ecoli(display_long)|uniprotkb:casB(gene name)|psi-mi:casB(display_short)|uniprotkb:cse2(gene name synonym)|uniprotkb:ygcK(gene name synonym)|uniprotkb:JW2729(locus name)|uniprotkb:b2759(locus name) psi-mi:cas6_ecoli(display_long)|uniprotkb:casE(gene name)|psi-mi:casE(display_short)|uniprotkb:CasE endoRNase(gene name synonym)|uniprotkb:cas6e(gene name synonym)|uniprotkb:crRNA endonuclease(gene name synonym)|uniprotkb:ygcH(gene name synonym)|uniprotkb:JW2726(locus name)|uniprotkb:b2756(locus name) psi-mi:"MI:0096"(pull down) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16116575|imex:IM-23358-1|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417239.1|refseq:WP_000752800.1|ensemblbacteria:AAC75801(transcript)|ensemblbacteria:b2759(gene)|ensemblbacteria:BAE76836(gene)|ensemblbacteria:BAE76836(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013382(CRISPR-associated protein Cse2)|interpro:IPR038287|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|dip:DIP-12127N refseq:WP_000281400.1|ensemblbacteria:AAC75798(transcript)|ensemblbacteria:b2756(gene)|ensemblbacteria:BAE76833(gene)|ensemblbacteria:BAE76833(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0006396"(RNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR010179(CRISPR-associated protein, CT1974)|rcsb pdb:4DZD|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417236.1|dip:DIP-12124N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:/oBgRIAB+RznxTXcjJjExZUOIgI83333 rogid:NrI5g6j3p3qJgyQvMa0Naz9mGkY83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P76632 uniprotkb:Q46898 intact:EBI-1125571|uniprotkb:Q2MA70|uniprotkb:Q46900|ensemblbacteria:AAC75801|ensemblbacteria:BAE76836 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 psi-mi:cse2_ecoli(display_long)|uniprotkb:casB(gene name)|psi-mi:casB(display_short)|uniprotkb:cse2(gene name synonym)|uniprotkb:ygcK(gene name synonym)|uniprotkb:JW2729(locus name)|uniprotkb:b2759(locus name) psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:"MI:0096"(pull down) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16116575|imex:IM-23358-1|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417239.1|refseq:WP_000752800.1|ensemblbacteria:AAC75801(transcript)|ensemblbacteria:b2759(gene)|ensemblbacteria:BAE76836(gene)|ensemblbacteria:BAE76836(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013382(CRISPR-associated protein Cse2)|interpro:IPR038287|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|dip:DIP-12127N ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:/oBgRIAB+RznxTXcjJjExZUOIgI83333 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P76632 uniprotkb:Q46899 intact:EBI-1125571|uniprotkb:Q2MA70|uniprotkb:Q46900|ensemblbacteria:AAC75801|ensemblbacteria:BAE76836 intact:EBI-1130226|uniprotkb:Q2MA71|ensemblbacteria:AAC75800|ensemblbacteria:BAE76835 psi-mi:cse2_ecoli(display_long)|uniprotkb:casB(gene name)|psi-mi:casB(display_short)|uniprotkb:cse2(gene name synonym)|uniprotkb:ygcK(gene name synonym)|uniprotkb:JW2729(locus name)|uniprotkb:b2759(locus name) psi-mi:casc_ecoli(display_long)|uniprotkb:casC(gene name)|psi-mi:casC(display_short)|uniprotkb:cas4(gene name synonym)|uniprotkb:cse4(gene name synonym)|uniprotkb:ygcJ(gene name synonym)|uniprotkb:JW2728(locus name)|uniprotkb:b2758(locus name) psi-mi:"MI:0096"(pull down) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16116575|imex:IM-23358-1|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417239.1|refseq:WP_000752800.1|ensemblbacteria:AAC75801(transcript)|ensemblbacteria:b2759(gene)|ensemblbacteria:BAE76836(gene)|ensemblbacteria:BAE76836(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013382(CRISPR-associated protein Cse2)|interpro:IPR038287|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|dip:DIP-12127N refseq:WP_000064450.1|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|rcsb pdb:4QYZ|ensemblbacteria:AAC75800(transcript)|ensemblbacteria:b2758(gene)|ensemblbacteria:BAE76835(gene)|ensemblbacteria:BAE76835(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010148(CRISPR-associated protein, CT1975)|refseq:NP_417238.1|dip:DIP-12126N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:/oBgRIAB+RznxTXcjJjExZUOIgI83333 rogid:Ai/XaHoqLUocieSkXZ5HgSs6jJU83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false his tag:n-n mutation disrupting interaction strength:204-206,200-200 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P76632 uniprotkb:Q46901 intact:EBI-1125571|uniprotkb:Q2MA70|uniprotkb:Q46900|ensemblbacteria:AAC75801|ensemblbacteria:BAE76836 intact:EBI-1130234|uniprotkb:Q2MA69|ensemblbacteria:AAC75802|ensemblbacteria:BAE76837 psi-mi:cse2_ecoli(display_long)|uniprotkb:casB(gene name)|psi-mi:casB(display_short)|uniprotkb:cse2(gene name synonym)|uniprotkb:ygcK(gene name synonym)|uniprotkb:JW2729(locus name)|uniprotkb:b2759(locus name) psi-mi:cse1_ecoli(display_long)|uniprotkb:casA(gene name)|psi-mi:casA(display_short)|uniprotkb:cse1(gene name synonym)|uniprotkb:ygcL(gene name synonym)|uniprotkb:JW2730(locus name)|uniprotkb:b2760(locus name)|uniprotkb:CRISPR type I-E/Ecoli-associated protein CasA/Cse1(gene name synonym)|uniprotkb:CRISPR-associated protein CasA/Cse1(gene name synonym) psi-mi:"MI:0096"(pull down) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16116575|imex:IM-23358-1|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417239.1|refseq:WP_000752800.1|ensemblbacteria:AAC75801(transcript)|ensemblbacteria:b2759(gene)|ensemblbacteria:BAE76836(gene)|ensemblbacteria:BAE76836(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013382(CRISPR-associated protein Cse2)|interpro:IPR038287|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|dip:DIP-12127N refseq:WP_001050401.1|ensemblbacteria:AAC75802(transcript)|ensemblbacteria:b2760(gene)|ensemblbacteria:BAE76837(gene)|ensemblbacteria:BAE76837(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013381(CRISPR-associated protein Cse1)|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9F|rcsb pdb:5H9E|refseq:NP_417240.1|dip:DIP-12128N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:/oBgRIAB+RznxTXcjJjExZUOIgI83333 rogid:qGf4NGF1E1MtBv00r6kyn7sS+B483333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q46898 uniprotkb:Q46897 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 intact:EBI-1130217|uniprotkb:Q2MA73|ensemblbacteria:AAC75798|ensemblbacteria:BAE76833 psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:cas6_ecoli(display_long)|uniprotkb:casE(gene name)|psi-mi:casE(display_short)|uniprotkb:CasE endoRNase(gene name synonym)|uniprotkb:cas6e(gene name synonym)|uniprotkb:crRNA endonuclease(gene name synonym)|uniprotkb:ygcH(gene name synonym)|uniprotkb:JW2726(locus name)|uniprotkb:b2756(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16116621|imex:IM-23358-3|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N refseq:WP_000281400.1|ensemblbacteria:AAC75798(transcript)|ensemblbacteria:b2756(gene)|ensemblbacteria:BAE76833(gene)|ensemblbacteria:BAE76833(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0006396"(RNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR010179(CRISPR-associated protein, CT1974)|rcsb pdb:4DZD|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417236.1|dip:DIP-12124N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rogid:NrI5g6j3p3qJgyQvMa0Naz9mGkY83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q46898 uniprotkb:Q46899 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 intact:EBI-1130226|uniprotkb:Q2MA71|ensemblbacteria:AAC75800|ensemblbacteria:BAE76835 psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:casc_ecoli(display_long)|uniprotkb:casC(gene name)|psi-mi:casC(display_short)|uniprotkb:cas4(gene name synonym)|uniprotkb:cse4(gene name synonym)|uniprotkb:ygcJ(gene name synonym)|uniprotkb:JW2728(locus name)|uniprotkb:b2758(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16116621|imex:IM-23358-3|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N refseq:WP_000064450.1|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|rcsb pdb:4QYZ|ensemblbacteria:AAC75800(transcript)|ensemblbacteria:b2758(gene)|ensemblbacteria:BAE76835(gene)|ensemblbacteria:BAE76835(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010148(CRISPR-associated protein, CT1975)|refseq:NP_417238.1|dip:DIP-12126N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rogid:Ai/XaHoqLUocieSkXZ5HgSs6jJU83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q46898 uniprotkb:Q46901 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 intact:EBI-1130234|uniprotkb:Q2MA69|ensemblbacteria:AAC75802|ensemblbacteria:BAE76837 psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:cse1_ecoli(display_long)|uniprotkb:casA(gene name)|psi-mi:casA(display_short)|uniprotkb:cse1(gene name synonym)|uniprotkb:ygcL(gene name synonym)|uniprotkb:JW2730(locus name)|uniprotkb:b2760(locus name)|uniprotkb:CRISPR type I-E/Ecoli-associated protein CasA/Cse1(gene name synonym)|uniprotkb:CRISPR-associated protein CasA/Cse1(gene name synonym) psi-mi:"MI:0226"(ion exchange chromatography) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16116621|imex:IM-23358-3|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N refseq:WP_001050401.1|ensemblbacteria:AAC75802(transcript)|ensemblbacteria:b2760(gene)|ensemblbacteria:BAE76837(gene)|ensemblbacteria:BAE76837(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013381(CRISPR-associated protein Cse1)|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9F|rcsb pdb:5H9E|refseq:NP_417240.1|dip:DIP-12128N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rogid:qGf4NGF1E1MtBv00r6kyn7sS+B483333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q46898 uniprotkb:P76632 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 intact:EBI-1125571|uniprotkb:Q2MA70|uniprotkb:Q46900|ensemblbacteria:AAC75801|ensemblbacteria:BAE76836 psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:cse2_ecoli(display_long)|uniprotkb:casB(gene name)|psi-mi:casB(display_short)|uniprotkb:cse2(gene name synonym)|uniprotkb:ygcK(gene name synonym)|uniprotkb:JW2729(locus name)|uniprotkb:b2759(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16116621|imex:IM-23358-3|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N refseq:NP_417239.1|refseq:WP_000752800.1|ensemblbacteria:AAC75801(transcript)|ensemblbacteria:b2759(gene)|ensemblbacteria:BAE76836(gene)|ensemblbacteria:BAE76836(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013382(CRISPR-associated protein Cse2)|interpro:IPR038287|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|dip:DIP-12127N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rogid:/oBgRIAB+RznxTXcjJjExZUOIgI83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q46898 uniprotkb:Q46897 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 intact:EBI-1130217|uniprotkb:Q2MA73|ensemblbacteria:AAC75798|ensemblbacteria:BAE76833 psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:cas6_ecoli(display_long)|uniprotkb:casE(gene name)|psi-mi:casE(display_short)|uniprotkb:CasE endoRNase(gene name synonym)|uniprotkb:cas6e(gene name synonym)|uniprotkb:crRNA endonuclease(gene name synonym)|uniprotkb:ygcH(gene name synonym)|uniprotkb:JW2726(locus name)|uniprotkb:b2756(locus name) psi-mi:"MI:0071"(molecular sieving) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16116641|imex:IM-23358-4|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N refseq:WP_000281400.1|ensemblbacteria:AAC75798(transcript)|ensemblbacteria:b2756(gene)|ensemblbacteria:BAE76833(gene)|ensemblbacteria:BAE76833(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0006396"(RNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR010179(CRISPR-associated protein, CT1974)|rcsb pdb:4DZD|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417236.1|dip:DIP-12124N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rogid:NrI5g6j3p3qJgyQvMa0Naz9mGkY83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false necessary binding region:75-104 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q46898 uniprotkb:Q46899 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 intact:EBI-1130226|uniprotkb:Q2MA71|ensemblbacteria:AAC75800|ensemblbacteria:BAE76835 psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:casc_ecoli(display_long)|uniprotkb:casC(gene name)|psi-mi:casC(display_short)|uniprotkb:cas4(gene name synonym)|uniprotkb:cse4(gene name synonym)|uniprotkb:ygcJ(gene name synonym)|uniprotkb:JW2728(locus name)|uniprotkb:b2758(locus name) psi-mi:"MI:0071"(molecular sieving) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16116641|imex:IM-23358-4|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N refseq:WP_000064450.1|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|rcsb pdb:4QYZ|ensemblbacteria:AAC75800(transcript)|ensemblbacteria:b2758(gene)|ensemblbacteria:BAE76835(gene)|ensemblbacteria:BAE76835(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010148(CRISPR-associated protein, CT1975)|refseq:NP_417238.1|dip:DIP-12126N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rogid:Ai/XaHoqLUocieSkXZ5HgSs6jJU83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false necessary binding region:75-104 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q46898 uniprotkb:Q46901 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 intact:EBI-1130234|uniprotkb:Q2MA69|ensemblbacteria:AAC75802|ensemblbacteria:BAE76837 psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:cse1_ecoli(display_long)|uniprotkb:casA(gene name)|psi-mi:casA(display_short)|uniprotkb:cse1(gene name synonym)|uniprotkb:ygcL(gene name synonym)|uniprotkb:JW2730(locus name)|uniprotkb:b2760(locus name)|uniprotkb:CRISPR type I-E/Ecoli-associated protein CasA/Cse1(gene name synonym)|uniprotkb:CRISPR-associated protein CasA/Cse1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16116641|imex:IM-23358-4|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N refseq:WP_001050401.1|ensemblbacteria:AAC75802(transcript)|ensemblbacteria:b2760(gene)|ensemblbacteria:BAE76837(gene)|ensemblbacteria:BAE76837(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013381(CRISPR-associated protein Cse1)|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9F|rcsb pdb:5H9E|refseq:NP_417240.1|dip:DIP-12128N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rogid:qGf4NGF1E1MtBv00r6kyn7sS+B483333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false necessary binding region:75-104 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q46898 uniprotkb:P76632 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 intact:EBI-1125571|uniprotkb:Q2MA70|uniprotkb:Q46900|ensemblbacteria:AAC75801|ensemblbacteria:BAE76836 psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:cse2_ecoli(display_long)|uniprotkb:casB(gene name)|psi-mi:casB(display_short)|uniprotkb:cse2(gene name synonym)|uniprotkb:ygcK(gene name synonym)|uniprotkb:JW2729(locus name)|uniprotkb:b2759(locus name) psi-mi:"MI:0071"(molecular sieving) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16116641|imex:IM-23358-4|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N refseq:NP_417239.1|refseq:WP_000752800.1|ensemblbacteria:AAC75801(transcript)|ensemblbacteria:b2759(gene)|ensemblbacteria:BAE76836(gene)|ensemblbacteria:BAE76836(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013382(CRISPR-associated protein Cse2)|interpro:IPR038287|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|dip:DIP-12127N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rogid:/oBgRIAB+RznxTXcjJjExZUOIgI83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false necessary binding region:75-104 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q46898 uniprotkb:Q46897 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 intact:EBI-1130217|uniprotkb:Q2MA73|ensemblbacteria:AAC75798|ensemblbacteria:BAE76833 psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:cas6_ecoli(display_long)|uniprotkb:casE(gene name)|psi-mi:casE(display_short)|uniprotkb:CasE endoRNase(gene name synonym)|uniprotkb:cas6e(gene name synonym)|uniprotkb:crRNA endonuclease(gene name synonym)|uniprotkb:ygcH(gene name synonym)|uniprotkb:JW2726(locus name)|uniprotkb:b2756(locus name) psi-mi:"MI:0071"(molecular sieving) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16116663|imex:IM-23358-5|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N refseq:WP_000281400.1|ensemblbacteria:AAC75798(transcript)|ensemblbacteria:b2756(gene)|ensemblbacteria:BAE76833(gene)|ensemblbacteria:BAE76833(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0006396"(RNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR010179(CRISPR-associated protein, CT1974)|rcsb pdb:4DZD|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417236.1|dip:DIP-12124N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rogid:NrI5g6j3p3qJgyQvMa0Naz9mGkY83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q46898 uniprotkb:Q46899 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 intact:EBI-1130226|uniprotkb:Q2MA71|ensemblbacteria:AAC75800|ensemblbacteria:BAE76835 psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:casc_ecoli(display_long)|uniprotkb:casC(gene name)|psi-mi:casC(display_short)|uniprotkb:cas4(gene name synonym)|uniprotkb:cse4(gene name synonym)|uniprotkb:ygcJ(gene name synonym)|uniprotkb:JW2728(locus name)|uniprotkb:b2758(locus name) psi-mi:"MI:0071"(molecular sieving) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16116663|imex:IM-23358-5|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N refseq:WP_000064450.1|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|rcsb pdb:4QYZ|ensemblbacteria:AAC75800(transcript)|ensemblbacteria:b2758(gene)|ensemblbacteria:BAE76835(gene)|ensemblbacteria:BAE76835(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010148(CRISPR-associated protein, CT1975)|refseq:NP_417238.1|dip:DIP-12126N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rogid:Ai/XaHoqLUocieSkXZ5HgSs6jJU83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false - mutation disrupting interaction strength:204-206,200-200 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q46898 uniprotkb:Q46901 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 intact:EBI-1130234|uniprotkb:Q2MA69|ensemblbacteria:AAC75802|ensemblbacteria:BAE76837 psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:cse1_ecoli(display_long)|uniprotkb:casA(gene name)|psi-mi:casA(display_short)|uniprotkb:cse1(gene name synonym)|uniprotkb:ygcL(gene name synonym)|uniprotkb:JW2730(locus name)|uniprotkb:b2760(locus name)|uniprotkb:CRISPR type I-E/Ecoli-associated protein CasA/Cse1(gene name synonym)|uniprotkb:CRISPR-associated protein CasA/Cse1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16116663|imex:IM-23358-5|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N refseq:WP_001050401.1|ensemblbacteria:AAC75802(transcript)|ensemblbacteria:b2760(gene)|ensemblbacteria:BAE76837(gene)|ensemblbacteria:BAE76837(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013381(CRISPR-associated protein Cse1)|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9F|rcsb pdb:5H9E|refseq:NP_417240.1|dip:DIP-12128N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rogid:qGf4NGF1E1MtBv00r6kyn7sS+B483333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q46898 uniprotkb:P76632 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 intact:EBI-1125571|uniprotkb:Q2MA70|uniprotkb:Q46900|ensemblbacteria:AAC75801|ensemblbacteria:BAE76836 psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:cse2_ecoli(display_long)|uniprotkb:casB(gene name)|psi-mi:casB(display_short)|uniprotkb:cse2(gene name synonym)|uniprotkb:ygcK(gene name synonym)|uniprotkb:JW2729(locus name)|uniprotkb:b2759(locus name) psi-mi:"MI:0071"(molecular sieving) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16116663|imex:IM-23358-5|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N refseq:NP_417239.1|refseq:WP_000752800.1|ensemblbacteria:AAC75801(transcript)|ensemblbacteria:b2759(gene)|ensemblbacteria:BAE76836(gene)|ensemblbacteria:BAE76836(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013382(CRISPR-associated protein Cse2)|interpro:IPR038287|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|dip:DIP-12127N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rogid:/oBgRIAB+RznxTXcjJjExZUOIgI83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q46898 uniprotkb:Q46897 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 intact:EBI-1130217|uniprotkb:Q2MA73|ensemblbacteria:AAC75798|ensemblbacteria:BAE76833 psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:cas6_ecoli(display_long)|uniprotkb:casE(gene name)|psi-mi:casE(display_short)|uniprotkb:CasE endoRNase(gene name synonym)|uniprotkb:cas6e(gene name synonym)|uniprotkb:crRNA endonuclease(gene name synonym)|uniprotkb:ygcH(gene name synonym)|uniprotkb:JW2726(locus name)|uniprotkb:b2756(locus name) psi-mi:"MI:0114"(x-ray crystallography) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16116601|imex:IM-23358-2|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N refseq:WP_000281400.1|ensemblbacteria:AAC75798(transcript)|ensemblbacteria:b2756(gene)|ensemblbacteria:BAE76833(gene)|ensemblbacteria:BAE76833(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0006396"(RNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR010179(CRISPR-associated protein, CT1974)|rcsb pdb:4DZD|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417236.1|dip:DIP-12124N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rogid:NrI5g6j3p3qJgyQvMa0Naz9mGkY83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q46898 uniprotkb:Q46899 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 intact:EBI-1130226|uniprotkb:Q2MA71|ensemblbacteria:AAC75800|ensemblbacteria:BAE76835 psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:casc_ecoli(display_long)|uniprotkb:casC(gene name)|psi-mi:casC(display_short)|uniprotkb:cas4(gene name synonym)|uniprotkb:cse4(gene name synonym)|uniprotkb:ygcJ(gene name synonym)|uniprotkb:JW2728(locus name)|uniprotkb:b2758(locus name) psi-mi:"MI:0114"(x-ray crystallography) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16116601|imex:IM-23358-2|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N refseq:WP_000064450.1|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|rcsb pdb:4QYZ|ensemblbacteria:AAC75800(transcript)|ensemblbacteria:b2758(gene)|ensemblbacteria:BAE76835(gene)|ensemblbacteria:BAE76835(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010148(CRISPR-associated protein, CT1975)|refseq:NP_417238.1|dip:DIP-12126N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rogid:Ai/XaHoqLUocieSkXZ5HgSs6jJU83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q46898 uniprotkb:Q46901 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 intact:EBI-1130234|uniprotkb:Q2MA69|ensemblbacteria:AAC75802|ensemblbacteria:BAE76837 psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:cse1_ecoli(display_long)|uniprotkb:casA(gene name)|psi-mi:casA(display_short)|uniprotkb:cse1(gene name synonym)|uniprotkb:ygcL(gene name synonym)|uniprotkb:JW2730(locus name)|uniprotkb:b2760(locus name)|uniprotkb:CRISPR type I-E/Ecoli-associated protein CasA/Cse1(gene name synonym)|uniprotkb:CRISPR-associated protein CasA/Cse1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16116601|imex:IM-23358-2|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N refseq:WP_001050401.1|ensemblbacteria:AAC75802(transcript)|ensemblbacteria:b2760(gene)|ensemblbacteria:BAE76837(gene)|ensemblbacteria:BAE76837(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013381(CRISPR-associated protein Cse1)|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9F|rcsb pdb:5H9E|refseq:NP_417240.1|dip:DIP-12128N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rogid:qGf4NGF1E1MtBv00r6kyn7sS+B483333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q46898 uniprotkb:P76632 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 intact:EBI-1125571|uniprotkb:Q2MA70|uniprotkb:Q46900|ensemblbacteria:AAC75801|ensemblbacteria:BAE76836 psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:cse2_ecoli(display_long)|uniprotkb:casB(gene name)|psi-mi:casB(display_short)|uniprotkb:cse2(gene name synonym)|uniprotkb:ygcK(gene name synonym)|uniprotkb:JW2729(locus name)|uniprotkb:b2759(locus name) psi-mi:"MI:0114"(x-ray crystallography) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16116601|imex:IM-23358-2|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N refseq:NP_417239.1|refseq:WP_000752800.1|ensemblbacteria:AAC75801(transcript)|ensemblbacteria:b2759(gene)|ensemblbacteria:BAE76836(gene)|ensemblbacteria:BAE76836(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013382(CRISPR-associated protein Cse2)|interpro:IPR038287|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|dip:DIP-12127N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rogid:/oBgRIAB+RznxTXcjJjExZUOIgI83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P76632 uniprotkb:Q46897 intact:EBI-1125571|uniprotkb:Q2MA70|uniprotkb:Q46900|ensemblbacteria:AAC75801|ensemblbacteria:BAE76836 intact:EBI-1130217|uniprotkb:Q2MA73|ensemblbacteria:AAC75798|ensemblbacteria:BAE76833 psi-mi:cse2_ecoli(display_long)|uniprotkb:casB(gene name)|psi-mi:casB(display_short)|uniprotkb:cse2(gene name synonym)|uniprotkb:ygcK(gene name synonym)|uniprotkb:JW2729(locus name)|uniprotkb:b2759(locus name) psi-mi:cas6_ecoli(display_long)|uniprotkb:casE(gene name)|psi-mi:casE(display_short)|uniprotkb:CasE endoRNase(gene name synonym)|uniprotkb:cas6e(gene name synonym)|uniprotkb:crRNA endonuclease(gene name synonym)|uniprotkb:ygcH(gene name synonym)|uniprotkb:JW2726(locus name)|uniprotkb:b2756(locus name) psi-mi:"MI:0096"(pull down) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16116686|imex:IM-23358-6|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417239.1|refseq:WP_000752800.1|ensemblbacteria:AAC75801(transcript)|ensemblbacteria:b2759(gene)|ensemblbacteria:BAE76836(gene)|ensemblbacteria:BAE76836(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013382(CRISPR-associated protein Cse2)|interpro:IPR038287|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|dip:DIP-12127N refseq:WP_000281400.1|ensemblbacteria:AAC75798(transcript)|ensemblbacteria:b2756(gene)|ensemblbacteria:BAE76833(gene)|ensemblbacteria:BAE76833(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0006396"(RNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR010179(CRISPR-associated protein, CT1974)|rcsb pdb:4DZD|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417236.1|dip:DIP-12124N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:/oBgRIAB+RznxTXcjJjExZUOIgI83333 rogid:NrI5g6j3p3qJgyQvMa0Naz9mGkY83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P76632 uniprotkb:Q46898 intact:EBI-1125571|uniprotkb:Q2MA70|uniprotkb:Q46900|ensemblbacteria:AAC75801|ensemblbacteria:BAE76836 intact:EBI-13639846|ensemblbacteria:AAC75799|ensemblbacteria:BAE76834|uniprotkb:Q2MA72 psi-mi:cse2_ecoli(display_long)|uniprotkb:casB(gene name)|psi-mi:casB(display_short)|uniprotkb:cse2(gene name synonym)|uniprotkb:ygcK(gene name synonym)|uniprotkb:JW2729(locus name)|uniprotkb:b2759(locus name) psi-mi:cas5_ecoli(display_long)|uniprotkb:casD(gene name)|psi-mi:casD(display_short)|uniprotkb:cas5(gene name synonym)|uniprotkb:ygcI(gene name synonym)|uniprotkb:b2757(locus name)|uniprotkb:JW5844(locus name) psi-mi:"MI:0096"(pull down) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16116686|imex:IM-23358-6|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417239.1|refseq:WP_000752800.1|ensemblbacteria:AAC75801(transcript)|ensemblbacteria:b2759(gene)|ensemblbacteria:BAE76836(gene)|ensemblbacteria:BAE76836(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013382(CRISPR-associated protein Cse2)|interpro:IPR038287|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|dip:DIP-12127N ensemblbacteria:AAC75799(transcript)|ensemblbacteria:b2757(gene)|ensemblbacteria:BAE76834(gene)|ensemblbacteria:BAE76834(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043571"(maintenance of CRISPR repeat elements)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010147(CRISPR-associated protein, CT1976)|interpro:IPR013422(CRISPR-associated protein Cas5)|interpro:IPR021124|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|refseq:NP_417237.2|refseq:WP_001334996.1|dip:DIP-12125N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:/oBgRIAB+RznxTXcjJjExZUOIgI83333 rogid:zKArwKcMu3lKlEbVto449t3bZ7I83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false his tag:n-n necessary binding region:75-104 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P76632 uniprotkb:Q46899 intact:EBI-1125571|uniprotkb:Q2MA70|uniprotkb:Q46900|ensemblbacteria:AAC75801|ensemblbacteria:BAE76836 intact:EBI-1130226|uniprotkb:Q2MA71|ensemblbacteria:AAC75800|ensemblbacteria:BAE76835 psi-mi:cse2_ecoli(display_long)|uniprotkb:casB(gene name)|psi-mi:casB(display_short)|uniprotkb:cse2(gene name synonym)|uniprotkb:ygcK(gene name synonym)|uniprotkb:JW2729(locus name)|uniprotkb:b2759(locus name) psi-mi:casc_ecoli(display_long)|uniprotkb:casC(gene name)|psi-mi:casC(display_short)|uniprotkb:cas4(gene name synonym)|uniprotkb:cse4(gene name synonym)|uniprotkb:ygcJ(gene name synonym)|uniprotkb:JW2728(locus name)|uniprotkb:b2758(locus name) psi-mi:"MI:0096"(pull down) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16116686|imex:IM-23358-6|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417239.1|refseq:WP_000752800.1|ensemblbacteria:AAC75801(transcript)|ensemblbacteria:b2759(gene)|ensemblbacteria:BAE76836(gene)|ensemblbacteria:BAE76836(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013382(CRISPR-associated protein Cse2)|interpro:IPR038287|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|dip:DIP-12127N refseq:WP_000064450.1|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|rcsb pdb:4QYZ|ensemblbacteria:AAC75800(transcript)|ensemblbacteria:b2758(gene)|ensemblbacteria:BAE76835(gene)|ensemblbacteria:BAE76835(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR010148(CRISPR-associated protein, CT1975)|refseq:NP_417238.1|dip:DIP-12126N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:/oBgRIAB+RznxTXcjJjExZUOIgI83333 rogid:Ai/XaHoqLUocieSkXZ5HgSs6jJU83333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P76632 uniprotkb:Q46901 intact:EBI-1125571|uniprotkb:Q2MA70|uniprotkb:Q46900|ensemblbacteria:AAC75801|ensemblbacteria:BAE76836 intact:EBI-1130234|uniprotkb:Q2MA69|ensemblbacteria:AAC75802|ensemblbacteria:BAE76837 psi-mi:cse2_ecoli(display_long)|uniprotkb:casB(gene name)|psi-mi:casB(display_short)|uniprotkb:cse2(gene name synonym)|uniprotkb:ygcK(gene name synonym)|uniprotkb:JW2729(locus name)|uniprotkb:b2759(locus name) psi-mi:cse1_ecoli(display_long)|uniprotkb:casA(gene name)|psi-mi:casA(display_short)|uniprotkb:cse1(gene name synonym)|uniprotkb:ygcL(gene name synonym)|uniprotkb:JW2730(locus name)|uniprotkb:b2760(locus name)|uniprotkb:CRISPR type I-E/Ecoli-associated protein CasA/Cse1(gene name synonym)|uniprotkb:CRISPR-associated protein CasA/Cse1(gene name synonym) psi-mi:"MI:0096"(pull down) Zhao et al. (2014) pubmed:25118175|doi:10.1038/nature13733|imex:IM-23358 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16116686|imex:IM-23358-6|dip:DIP-186992E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417239.1|refseq:WP_000752800.1|ensemblbacteria:AAC75801(transcript)|ensemblbacteria:b2759(gene)|ensemblbacteria:BAE76836(gene)|ensemblbacteria:BAE76836(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013382(CRISPR-associated protein Cse2)|interpro:IPR038287|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9E|rcsb pdb:5H9F|dip:DIP-12127N refseq:WP_001050401.1|ensemblbacteria:AAC75802(transcript)|ensemblbacteria:b2760(gene)|ensemblbacteria:BAE76837(gene)|ensemblbacteria:BAE76837(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051607"(defense response to virus)|interpro:IPR013381(CRISPR-associated protein Cse1)|rcsb pdb:4QYZ|rcsb pdb:4TVX|rcsb pdb:4U7U|rcsb pdb:5CD4|rcsb pdb:5H9F|rcsb pdb:5H9E|refseq:NP_417240.1|dip:DIP-12128N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:/oBgRIAB+RznxTXcjJjExZUOIgI83333 rogid:qGf4NGF1E1MtBv00r6kyn7sS+B483333 rigid:XqmkYkKVQFuvy2O4HjFduuEUwcs false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)