#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q12229	uniprotkb:P36096	intact:EBI-35335|uniprotkb:D6VRQ7|ensemblfungi:YDL091C	intact:EBI-26635|uniprotkb:D6VXQ1|ensemblfungi:YKL034W	psi-mi:ubx3_yeast(display_long)|uniprotkb:UBX3(gene name)|psi-mi:UBX3(display_short)|uniprotkb:YDL091C(locus name)	psi-mi:tul1_yeast(display_long)|uniprotkb:TUL1(gene name)|psi-mi:TUL1(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TUL1(gene name synonym)|uniprotkb:YKL247(orf name)|uniprotkb:YKL034W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tong et al. (2014)	imex:IM-25825|pubmed:25078903	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16031849|imex:IM-25825-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010192.1|sgd:S000002249|reactome:R-SCE-6798695|dip:DIP-5024N|ensemblfungi:YDL091C(gene)|ensemblfungi:YDL091C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR029071|interpro:IPR036249|reactome:R-SCE-8980692	refseq:NP_012890.1|sgd:S000001517|dip:DIP-5413N|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|ensemblfungi:YKL034W(gene)|ensemblfungi:YKL034W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005794"(Golgi apparatus)	-	crc64:7C565528A9C9D33E	-	figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/07	2017/08/07	rogid:RMj4tdOxWiFdV/JGE371TOlgldw559292	rogid:6L9Pk7v0AbwbD2HH3sq5IkIwnCg559292	rigid:LHHgYI4IHl2G9InJqAsxFx2/6o4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12229	uniprotkb:Q08232	intact:EBI-35335|uniprotkb:D6VRQ7|ensemblfungi:YDL091C	intact:EBI-32978|uniprotkb:D6W1Z4|ensemblfungi:YOL073C	psi-mi:ubx3_yeast(display_long)|uniprotkb:UBX3(gene name)|psi-mi:UBX3(display_short)|uniprotkb:YDL091C(locus name)	psi-mi:dsc2_yeast(display_long)|uniprotkb:DSC2(gene name)|psi-mi:DSC2(display_short)|uniprotkb:Defective for SREBP cleavage protein 2(gene name synonym)|uniprotkb:YOL073C(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tong et al. (2014)	imex:IM-25825|pubmed:25078903	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16031849|imex:IM-25825-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010192.1|sgd:S000002249|reactome:R-SCE-6798695|dip:DIP-5024N|ensemblfungi:YDL091C(gene)|ensemblfungi:YDL091C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR029071|interpro:IPR036249|reactome:R-SCE-8980692	sgd:S000005434|refseq:NP_014568.1|dip:DIP-4167N|ensemblfungi:YOL073C(gene)|ensemblfungi:YOL073C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|interpro:IPR035952	-	crc64:7C565528A9C9D33E	-	figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/07	2017/08/07	rogid:RMj4tdOxWiFdV/JGE371TOlgldw559292	rogid:MKUssSoJTVUXNmJyRKZiSNtd31E559292	rigid:LHHgYI4IHl2G9InJqAsxFx2/6o4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12229	uniprotkb:Q12015	intact:EBI-35335|uniprotkb:D6VRQ7|ensemblfungi:YDL091C	intact:EBI-31423|uniprotkb:D6W2S8|ensemblfungi:YOR223W	psi-mi:ubx3_yeast(display_long)|uniprotkb:UBX3(gene name)|psi-mi:UBX3(display_short)|uniprotkb:YDL091C(locus name)	psi-mi:dsc3_yeast(display_long)|uniprotkb:DSC3(gene name)|psi-mi:DSC3(display_short)|uniprotkb:Defective for SREBP cleavage protein 3(gene name synonym)|uniprotkb:YOR50-13(orf name)|uniprotkb:YOR223W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tong et al. (2014)	imex:IM-25825|pubmed:25078903	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16031849|imex:IM-25825-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010192.1|sgd:S000002249|reactome:R-SCE-6798695|dip:DIP-5024N|ensemblfungi:YDL091C(gene)|ensemblfungi:YDL091C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR029071|interpro:IPR036249|reactome:R-SCE-8980692	refseq:NP_014866.3|sgd:S000005749|interpro:IPR019413|interpro:IPR025390|ensemblfungi:YOR223W(gene)|ensemblfungi:YOR223W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)	-	crc64:7C565528A9C9D33E	-	figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/07	2017/08/07	rogid:RMj4tdOxWiFdV/JGE371TOlgldw559292	rogid:ebWSvkqYXzLugE3xFfu285Cil8Y559292	rigid:LHHgYI4IHl2G9InJqAsxFx2/6o4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12229	uniprotkb:Q08232	intact:EBI-35335|uniprotkb:D6VRQ7|ensemblfungi:YDL091C	intact:EBI-32978|uniprotkb:D6W1Z4|ensemblfungi:YOL073C	psi-mi:ubx3_yeast(display_long)|uniprotkb:UBX3(gene name)|psi-mi:UBX3(display_short)|uniprotkb:YDL091C(locus name)	psi-mi:dsc2_yeast(display_long)|uniprotkb:DSC2(gene name)|psi-mi:DSC2(display_short)|uniprotkb:Defective for SREBP cleavage protein 2(gene name synonym)|uniprotkb:YOL073C(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tong et al. (2014)	imex:IM-25825|pubmed:25078903	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16032100|imex:IM-25825-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010192.1|sgd:S000002249|reactome:R-SCE-6798695|dip:DIP-5024N|ensemblfungi:YDL091C(gene)|ensemblfungi:YDL091C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR029071|interpro:IPR036249|reactome:R-SCE-8980692	sgd:S000005434|refseq:NP_014568.1|dip:DIP-4167N|ensemblfungi:YOL073C(gene)|ensemblfungi:YOL073C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|interpro:IPR035952	-	crc64:7C565528A9C9D33E	-	figure legend:Fig. 3C|comment:Interaction observed in tul1-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/07	2017/08/07	rogid:RMj4tdOxWiFdV/JGE371TOlgldw559292	rogid:MKUssSoJTVUXNmJyRKZiSNtd31E559292	rigid:frJV1yjttCZe64i/yp7wHVX5abk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12229	uniprotkb:Q12015	intact:EBI-35335|uniprotkb:D6VRQ7|ensemblfungi:YDL091C	intact:EBI-31423|uniprotkb:D6W2S8|ensemblfungi:YOR223W	psi-mi:ubx3_yeast(display_long)|uniprotkb:UBX3(gene name)|psi-mi:UBX3(display_short)|uniprotkb:YDL091C(locus name)	psi-mi:dsc3_yeast(display_long)|uniprotkb:DSC3(gene name)|psi-mi:DSC3(display_short)|uniprotkb:Defective for SREBP cleavage protein 3(gene name synonym)|uniprotkb:YOR50-13(orf name)|uniprotkb:YOR223W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tong et al. (2014)	imex:IM-25825|pubmed:25078903	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16032100|imex:IM-25825-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010192.1|sgd:S000002249|reactome:R-SCE-6798695|dip:DIP-5024N|ensemblfungi:YDL091C(gene)|ensemblfungi:YDL091C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR029071|interpro:IPR036249|reactome:R-SCE-8980692	refseq:NP_014866.3|sgd:S000005749|interpro:IPR019413|interpro:IPR025390|ensemblfungi:YOR223W(gene)|ensemblfungi:YOR223W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)	-	crc64:7C565528A9C9D33E	-	figure legend:Fig. 3C|comment:Interaction observed in tul1-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/07	2017/08/07	rogid:RMj4tdOxWiFdV/JGE371TOlgldw559292	rogid:ebWSvkqYXzLugE3xFfu285Cil8Y559292	rigid:frJV1yjttCZe64i/yp7wHVX5abk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08232	uniprotkb:Q12229	intact:EBI-32978|uniprotkb:D6W1Z4|ensemblfungi:YOL073C	intact:EBI-35335|uniprotkb:D6VRQ7|ensemblfungi:YDL091C	psi-mi:dsc2_yeast(display_long)|uniprotkb:DSC2(gene name)|psi-mi:DSC2(display_short)|uniprotkb:Defective for SREBP cleavage protein 2(gene name synonym)|uniprotkb:YOL073C(locus name)	psi-mi:ubx3_yeast(display_long)|uniprotkb:UBX3(gene name)|psi-mi:UBX3(display_short)|uniprotkb:YDL091C(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tong et al. (2014)	imex:IM-25825|pubmed:25078903	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16032767|imex:IM-25825-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005434|refseq:NP_014568.1|dip:DIP-4167N|ensemblfungi:YOL073C(gene)|ensemblfungi:YOL073C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|interpro:IPR035952	refseq:NP_010192.1|sgd:S000002249|reactome:R-SCE-6798695|dip:DIP-5024N|ensemblfungi:YDL091C(gene)|ensemblfungi:YDL091C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR029071|interpro:IPR036249|reactome:R-SCE-8980692	-	-	crc64:7C565528A9C9D33E	figure legend:Fig. 3C|comment:Interaction observed in YOR223W -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/07	2017/08/07	rogid:MKUssSoJTVUXNmJyRKZiSNtd31E559292	rogid:RMj4tdOxWiFdV/JGE371TOlgldw559292	rigid:GlynN472u0Ga1ZfZ5EIvTNaN4OM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08232	uniprotkb:P36096	intact:EBI-32978|uniprotkb:D6W1Z4|ensemblfungi:YOL073C	intact:EBI-26635|uniprotkb:D6VXQ1|ensemblfungi:YKL034W	psi-mi:dsc2_yeast(display_long)|uniprotkb:DSC2(gene name)|psi-mi:DSC2(display_short)|uniprotkb:Defective for SREBP cleavage protein 2(gene name synonym)|uniprotkb:YOL073C(locus name)	psi-mi:tul1_yeast(display_long)|uniprotkb:TUL1(gene name)|psi-mi:TUL1(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TUL1(gene name synonym)|uniprotkb:YKL247(orf name)|uniprotkb:YKL034W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tong et al. (2014)	imex:IM-25825|pubmed:25078903	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16033293|imex:IM-25825-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005434|refseq:NP_014568.1|dip:DIP-4167N|ensemblfungi:YOL073C(gene)|ensemblfungi:YOL073C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|interpro:IPR035952	refseq:NP_012890.1|sgd:S000001517|dip:DIP-5413N|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|ensemblfungi:YKL034W(gene)|ensemblfungi:YKL034W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005794"(Golgi apparatus)	-	-	-	figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/07	2017/08/07	rogid:MKUssSoJTVUXNmJyRKZiSNtd31E559292	rogid:6L9Pk7v0AbwbD2HH3sq5IkIwnCg559292	rigid:LHHgYI4IHl2G9InJqAsxFx2/6o4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08232	uniprotkb:Q12015	intact:EBI-32978|uniprotkb:D6W1Z4|ensemblfungi:YOL073C	intact:EBI-31423|uniprotkb:D6W2S8|ensemblfungi:YOR223W	psi-mi:dsc2_yeast(display_long)|uniprotkb:DSC2(gene name)|psi-mi:DSC2(display_short)|uniprotkb:Defective for SREBP cleavage protein 2(gene name synonym)|uniprotkb:YOL073C(locus name)	psi-mi:dsc3_yeast(display_long)|uniprotkb:DSC3(gene name)|psi-mi:DSC3(display_short)|uniprotkb:Defective for SREBP cleavage protein 3(gene name synonym)|uniprotkb:YOR50-13(orf name)|uniprotkb:YOR223W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tong et al. (2014)	imex:IM-25825|pubmed:25078903	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16033293|imex:IM-25825-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005434|refseq:NP_014568.1|dip:DIP-4167N|ensemblfungi:YOL073C(gene)|ensemblfungi:YOL073C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|interpro:IPR035952	refseq:NP_014866.3|sgd:S000005749|interpro:IPR019413|interpro:IPR025390|ensemblfungi:YOR223W(gene)|ensemblfungi:YOR223W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)	-	-	-	figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/07	2017/08/07	rogid:MKUssSoJTVUXNmJyRKZiSNtd31E559292	rogid:ebWSvkqYXzLugE3xFfu285Cil8Y559292	rigid:LHHgYI4IHl2G9InJqAsxFx2/6o4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08232	uniprotkb:Q12229	intact:EBI-32978|uniprotkb:D6W1Z4|ensemblfungi:YOL073C	intact:EBI-35335|uniprotkb:D6VRQ7|ensemblfungi:YDL091C	psi-mi:dsc2_yeast(display_long)|uniprotkb:DSC2(gene name)|psi-mi:DSC2(display_short)|uniprotkb:Defective for SREBP cleavage protein 2(gene name synonym)|uniprotkb:YOL073C(locus name)	psi-mi:ubx3_yeast(display_long)|uniprotkb:UBX3(gene name)|psi-mi:UBX3(display_short)|uniprotkb:YDL091C(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tong et al. (2014)	imex:IM-25825|pubmed:25078903	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16033293|imex:IM-25825-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005434|refseq:NP_014568.1|dip:DIP-4167N|ensemblfungi:YOL073C(gene)|ensemblfungi:YOL073C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|interpro:IPR035952	refseq:NP_010192.1|sgd:S000002249|reactome:R-SCE-6798695|dip:DIP-5024N|ensemblfungi:YDL091C(gene)|ensemblfungi:YDL091C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR029071|interpro:IPR036249|reactome:R-SCE-8980692	-	-	crc64:7C565528A9C9D33E	figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/07	2017/08/07	rogid:MKUssSoJTVUXNmJyRKZiSNtd31E559292	rogid:RMj4tdOxWiFdV/JGE371TOlgldw559292	rigid:LHHgYI4IHl2G9InJqAsxFx2/6o4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08232	uniprotkb:Q12015	intact:EBI-32978|uniprotkb:D6W1Z4|ensemblfungi:YOL073C	intact:EBI-31423|uniprotkb:D6W2S8|ensemblfungi:YOR223W	psi-mi:dsc2_yeast(display_long)|uniprotkb:DSC2(gene name)|psi-mi:DSC2(display_short)|uniprotkb:Defective for SREBP cleavage protein 2(gene name synonym)|uniprotkb:YOL073C(locus name)	psi-mi:dsc3_yeast(display_long)|uniprotkb:DSC3(gene name)|psi-mi:DSC3(display_short)|uniprotkb:Defective for SREBP cleavage protein 3(gene name synonym)|uniprotkb:YOR50-13(orf name)|uniprotkb:YOR223W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tong et al. (2014)	imex:IM-25825|pubmed:25078903	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16034263|imex:IM-25825-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005434|refseq:NP_014568.1|dip:DIP-4167N|ensemblfungi:YOL073C(gene)|ensemblfungi:YOL073C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|interpro:IPR035952	refseq:NP_014866.3|sgd:S000005749|interpro:IPR019413|interpro:IPR025390|ensemblfungi:YOR223W(gene)|ensemblfungi:YOR223W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)	-	-	-	figure legend:Fig. 3A|comment:Interaction observed in tul1-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/07	2017/08/07	rogid:MKUssSoJTVUXNmJyRKZiSNtd31E559292	rogid:ebWSvkqYXzLugE3xFfu285Cil8Y559292	rigid:frJV1yjttCZe64i/yp7wHVX5abk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08232	uniprotkb:Q12229	intact:EBI-32978|uniprotkb:D6W1Z4|ensemblfungi:YOL073C	intact:EBI-35335|uniprotkb:D6VRQ7|ensemblfungi:YDL091C	psi-mi:dsc2_yeast(display_long)|uniprotkb:DSC2(gene name)|psi-mi:DSC2(display_short)|uniprotkb:Defective for SREBP cleavage protein 2(gene name synonym)|uniprotkb:YOL073C(locus name)	psi-mi:ubx3_yeast(display_long)|uniprotkb:UBX3(gene name)|psi-mi:UBX3(display_short)|uniprotkb:YDL091C(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tong et al. (2014)	imex:IM-25825|pubmed:25078903	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16034263|imex:IM-25825-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005434|refseq:NP_014568.1|dip:DIP-4167N|ensemblfungi:YOL073C(gene)|ensemblfungi:YOL073C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|interpro:IPR035952	refseq:NP_010192.1|sgd:S000002249|reactome:R-SCE-6798695|dip:DIP-5024N|ensemblfungi:YDL091C(gene)|ensemblfungi:YDL091C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR029071|interpro:IPR036249|reactome:R-SCE-8980692	-	-	crc64:7C565528A9C9D33E	figure legend:Fig. 3A|comment:Interaction observed in tul1-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/07	2017/08/07	rogid:MKUssSoJTVUXNmJyRKZiSNtd31E559292	rogid:RMj4tdOxWiFdV/JGE371TOlgldw559292	rigid:frJV1yjttCZe64i/yp7wHVX5abk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08232	uniprotkb:Q12229	intact:EBI-32978|uniprotkb:D6W1Z4|ensemblfungi:YOL073C	intact:EBI-35335|uniprotkb:D6VRQ7|ensemblfungi:YDL091C	psi-mi:dsc2_yeast(display_long)|uniprotkb:DSC2(gene name)|psi-mi:DSC2(display_short)|uniprotkb:Defective for SREBP cleavage protein 2(gene name synonym)|uniprotkb:YOL073C(locus name)	psi-mi:ubx3_yeast(display_long)|uniprotkb:UBX3(gene name)|psi-mi:UBX3(display_short)|uniprotkb:YDL091C(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tong et al. (2014)	imex:IM-25825|pubmed:25078903	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16034704|imex:IM-25825-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005434|refseq:NP_014568.1|dip:DIP-4167N|ensemblfungi:YOL073C(gene)|ensemblfungi:YOL073C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|interpro:IPR035952	refseq:NP_010192.1|sgd:S000002249|reactome:R-SCE-6798695|dip:DIP-5024N|ensemblfungi:YDL091C(gene)|ensemblfungi:YDL091C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR029071|interpro:IPR036249|reactome:R-SCE-8980692	-	-	crc64:7C565528A9C9D33E	figure legend:Fig. 3A|comment:Interaction observed in dsc3-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/07	2017/08/07	rogid:MKUssSoJTVUXNmJyRKZiSNtd31E559292	rogid:RMj4tdOxWiFdV/JGE371TOlgldw559292	rigid:GlynN472u0Ga1ZfZ5EIvTNaN4OM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12015	uniprotkb:P36096	intact:EBI-31423|uniprotkb:D6W2S8|ensemblfungi:YOR223W	intact:EBI-26635|uniprotkb:D6VXQ1|ensemblfungi:YKL034W	psi-mi:dsc3_yeast(display_long)|uniprotkb:DSC3(gene name)|psi-mi:DSC3(display_short)|uniprotkb:Defective for SREBP cleavage protein 3(gene name synonym)|uniprotkb:YOR50-13(orf name)|uniprotkb:YOR223W(locus name)	psi-mi:tul1_yeast(display_long)|uniprotkb:TUL1(gene name)|psi-mi:TUL1(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TUL1(gene name synonym)|uniprotkb:YKL247(orf name)|uniprotkb:YKL034W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tong et al. (2014)	imex:IM-25825|pubmed:25078903	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16035328|imex:IM-25825-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014866.3|sgd:S000005749|interpro:IPR019413|interpro:IPR025390|ensemblfungi:YOR223W(gene)|ensemblfungi:YOR223W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)	refseq:NP_012890.1|sgd:S000001517|dip:DIP-5413N|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|ensemblfungi:YKL034W(gene)|ensemblfungi:YKL034W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005794"(Golgi apparatus)	-	-	-	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/07	2017/08/07	rogid:ebWSvkqYXzLugE3xFfu285Cil8Y559292	rogid:6L9Pk7v0AbwbD2HH3sq5IkIwnCg559292	rigid:LHHgYI4IHl2G9InJqAsxFx2/6o4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12015	uniprotkb:Q08232	intact:EBI-31423|uniprotkb:D6W2S8|ensemblfungi:YOR223W	intact:EBI-32978|uniprotkb:D6W1Z4|ensemblfungi:YOL073C	psi-mi:dsc3_yeast(display_long)|uniprotkb:DSC3(gene name)|psi-mi:DSC3(display_short)|uniprotkb:Defective for SREBP cleavage protein 3(gene name synonym)|uniprotkb:YOR50-13(orf name)|uniprotkb:YOR223W(locus name)	psi-mi:dsc2_yeast(display_long)|uniprotkb:DSC2(gene name)|psi-mi:DSC2(display_short)|uniprotkb:Defective for SREBP cleavage protein 2(gene name synonym)|uniprotkb:YOL073C(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tong et al. (2014)	imex:IM-25825|pubmed:25078903	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16035328|imex:IM-25825-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014866.3|sgd:S000005749|interpro:IPR019413|interpro:IPR025390|ensemblfungi:YOR223W(gene)|ensemblfungi:YOR223W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)	sgd:S000005434|refseq:NP_014568.1|dip:DIP-4167N|ensemblfungi:YOL073C(gene)|ensemblfungi:YOL073C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|interpro:IPR035952	-	-	-	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/07	2017/08/07	rogid:ebWSvkqYXzLugE3xFfu285Cil8Y559292	rogid:MKUssSoJTVUXNmJyRKZiSNtd31E559292	rigid:LHHgYI4IHl2G9InJqAsxFx2/6o4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12015	uniprotkb:Q12229	intact:EBI-31423|uniprotkb:D6W2S8|ensemblfungi:YOR223W	intact:EBI-35335|uniprotkb:D6VRQ7|ensemblfungi:YDL091C	psi-mi:dsc3_yeast(display_long)|uniprotkb:DSC3(gene name)|psi-mi:DSC3(display_short)|uniprotkb:Defective for SREBP cleavage protein 3(gene name synonym)|uniprotkb:YOR50-13(orf name)|uniprotkb:YOR223W(locus name)	psi-mi:ubx3_yeast(display_long)|uniprotkb:UBX3(gene name)|psi-mi:UBX3(display_short)|uniprotkb:YDL091C(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tong et al. (2014)	imex:IM-25825|pubmed:25078903	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16035328|imex:IM-25825-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014866.3|sgd:S000005749|interpro:IPR019413|interpro:IPR025390|ensemblfungi:YOR223W(gene)|ensemblfungi:YOR223W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)	refseq:NP_010192.1|sgd:S000002249|reactome:R-SCE-6798695|dip:DIP-5024N|ensemblfungi:YDL091C(gene)|ensemblfungi:YDL091C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR029071|interpro:IPR036249|reactome:R-SCE-8980692	-	-	crc64:7C565528A9C9D33E	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/07	2017/08/07	rogid:ebWSvkqYXzLugE3xFfu285Cil8Y559292	rogid:RMj4tdOxWiFdV/JGE371TOlgldw559292	rigid:LHHgYI4IHl2G9InJqAsxFx2/6o4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12015	uniprotkb:Q08232	intact:EBI-31423|uniprotkb:D6W2S8|ensemblfungi:YOR223W	intact:EBI-32978|uniprotkb:D6W1Z4|ensemblfungi:YOL073C	psi-mi:dsc3_yeast(display_long)|uniprotkb:DSC3(gene name)|psi-mi:DSC3(display_short)|uniprotkb:Defective for SREBP cleavage protein 3(gene name synonym)|uniprotkb:YOR50-13(orf name)|uniprotkb:YOR223W(locus name)	psi-mi:dsc2_yeast(display_long)|uniprotkb:DSC2(gene name)|psi-mi:DSC2(display_short)|uniprotkb:Defective for SREBP cleavage protein 2(gene name synonym)|uniprotkb:YOL073C(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tong et al. (2014)	imex:IM-25825|pubmed:25078903	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16035334|imex:IM-25825-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014866.3|sgd:S000005749|interpro:IPR019413|interpro:IPR025390|ensemblfungi:YOR223W(gene)|ensemblfungi:YOR223W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)	sgd:S000005434|refseq:NP_014568.1|dip:DIP-4167N|ensemblfungi:YOL073C(gene)|ensemblfungi:YOL073C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|interpro:IPR035952	-	-	-	figure legend:Fig. 3B|comment:Interaction observed in tul1 -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/07	2017/08/07	rogid:ebWSvkqYXzLugE3xFfu285Cil8Y559292	rogid:MKUssSoJTVUXNmJyRKZiSNtd31E559292	rigid:frJV1yjttCZe64i/yp7wHVX5abk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12015	uniprotkb:Q12229	intact:EBI-31423|uniprotkb:D6W2S8|ensemblfungi:YOR223W	intact:EBI-35335|uniprotkb:D6VRQ7|ensemblfungi:YDL091C	psi-mi:dsc3_yeast(display_long)|uniprotkb:DSC3(gene name)|psi-mi:DSC3(display_short)|uniprotkb:Defective for SREBP cleavage protein 3(gene name synonym)|uniprotkb:YOR50-13(orf name)|uniprotkb:YOR223W(locus name)	psi-mi:ubx3_yeast(display_long)|uniprotkb:UBX3(gene name)|psi-mi:UBX3(display_short)|uniprotkb:YDL091C(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tong et al. (2014)	imex:IM-25825|pubmed:25078903	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16035334|imex:IM-25825-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014866.3|sgd:S000005749|interpro:IPR019413|interpro:IPR025390|ensemblfungi:YOR223W(gene)|ensemblfungi:YOR223W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)	refseq:NP_010192.1|sgd:S000002249|reactome:R-SCE-6798695|dip:DIP-5024N|ensemblfungi:YDL091C(gene)|ensemblfungi:YDL091C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR029071|interpro:IPR036249|reactome:R-SCE-8980692	-	-	crc64:7C565528A9C9D33E	figure legend:Fig. 3B|comment:Interaction observed in tul1 -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/08/07	2017/08/07	rogid:ebWSvkqYXzLugE3xFfu285Cil8Y559292	rogid:RMj4tdOxWiFdV/JGE371TOlgldw559292	rigid:frJV1yjttCZe64i/yp7wHVX5abk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)