#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P53859	uniprotkb:P48240	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1749|uniprotkb:D6VUT8|ensemblfungi:YGR158C	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:mtr3_yeast(display_long)|uniprotkb:MTR3(gene name)|psi-mi:MTR3(display_short)|uniprotkb:YGR158C(locus name)|uniprotkb:G6676(orf name)|uniprotkb:mRNA transport regulator 3(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114622|imex:IM-23146-1|dip:DIP-197202E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	sgd:S000003390|refseq:NP_011674.3|dip:DIP-931N|mint:P48240|ensemblfungi:YGR158C(gene)|ensemblfungi:YGR158C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:2FA07ABB4A1115E0	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:t5M0E3avqoJ0dbM51kE3fZlz2pc559292	rigid:jWZfd7kvzfPOo2l+CAtdF3+8Quk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53859	uniprotkb:Q08285	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1831|ensemblfungi:YOL142W|uniprotkb:D6W1S7|uniprotkb:E9P8Z4	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:rrp40_yeast(display_long)|uniprotkb:RRP40(gene name)|psi-mi:RRP40(display_short)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:YOL142W(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114622|imex:IM-23146-1|dip:DIP-197202E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	refseq:NP_014499.2|sgd:S000005502|ensemblfungi:YOL142W(gene)|ensemblfungi:YOL142W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030145"(manganese ion binding)|dip:DIP-5330N|mint:Q08285|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|interpro:IPR041054|rcsb pdb:2JA9|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:62B3A30348BBAA7C	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:3sdpWE2qP6cVgcD2b8VDWV0ox4g559292	rigid:jWZfd7kvzfPOo2l+CAtdF3+8Quk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53859	uniprotkb:P46948	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114622|imex:IM-23146-1|dip:DIP-197202E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:C80EFFB528A43044	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	rigid:jWZfd7kvzfPOo2l+CAtdF3+8Quk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53859	uniprotkb:Q12277	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1765|uniprotkb:D6VRN9|ensemblfungi:YDL111C	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:rrp42_yeast(display_long)|uniprotkb:RRP42(gene name)|psi-mi:RRP42(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:YDL111C(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114622|imex:IM-23146-1|dip:DIP-197202E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	refseq:NP_010172.1|sgd:S000002269|dip:DIP-1463N|mint:Q12277|ensemblfungi:YDL111C(gene)|ensemblfungi:YDL111C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:806C60979642C67E	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:OVyAr6b3ECMjQj3nUsuxXZqxt1o559292	rigid:jWZfd7kvzfPOo2l+CAtdF3+8Quk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53859	uniprotkb:P25359	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1773|uniprotkb:Q8NKJ5|ensemblfungi:YCR035C|uniprotkb:D6VR45	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:rrp43_yeast(display_long)|uniprotkb:RRP43(gene name)|psi-mi:RRP43(display_short)|uniprotkb:YCR035C(locus name)|uniprotkb:YCR35C(orf name)|uniprotkb:YCR522(orf name)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114622|imex:IM-23146-1|dip:DIP-197202E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	ensemblfungi:YCR035C(gene)|ensemblfungi:YCR035C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016072"(rRNA metabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|refseq:NP_009964.2|sgd:S000000631|dip:DIP-5485N|mint:P25359|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:8801837B8184134D	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:htGDTlKKMq7OdwcfGUKgfWCjJ1k559292	rigid:jWZfd7kvzfPOo2l+CAtdF3+8Quk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53859	uniprotkb:Q05636	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1810|uniprotkb:D6VSR0|ensemblfungi:YDR280W	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:rrp45_yeast(display_long)|uniprotkb:RRP45(gene name)|psi-mi:RRP45(display_short)|uniprotkb:YDR280W(locus name)|uniprotkb:D9954.1(orf name)|uniprotkb:Ribosomal RNA-processing protein 45(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114622|imex:IM-23146-1|dip:DIP-197202E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	refseq:NP_010566.1|sgd:S000002688|dip:DIP-2084N|mint:Q05636|ensemblfungi:YDR280W(gene)|ensemblfungi:YDR280W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:65C9DB5A63678F2D	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:LCdt9Nm8j2AD6iecBI2CGCrhEhQ559292	rigid:jWZfd7kvzfPOo2l+CAtdF3+8Quk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53859	uniprotkb:P53256	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1842|uniprotkb:Q6TQU1|uniprotkb:D6VUM7|ensemblfungi:YGR095C	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:rrp46_yeast(display_long)|uniprotkb:RRP46(gene name)|psi-mi:RRP46(display_short)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:YGR095C(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114622|imex:IM-23146-1|dip:DIP-197202E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	refseq:NP_011609.2|sgd:S000003327|dip:DIP-6838N|mint:P53256|ensemblfungi:YGR095C(gene)|ensemblfungi:YGR095C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:F1307E0EE4FC3133	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:2ESxObCiXUjTEvlB5ow7eCgivz0559292	rigid:jWZfd7kvzfPOo2l+CAtdF3+8Quk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53859	uniprotkb:P38792	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1757|uniprotkb:D3DL18|ensemblfungi:YHR069C	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:rrp4_yeast(display_long)|uniprotkb:RRP4(gene name)|psi-mi:RRP4(display_short)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:YHR069C(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114622|imex:IM-23146-1|dip:DIP-197202E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	refseq:NP_011936.1|sgd:S000001111|dip:DIP-5888N|mint:P38792|ensemblfungi:YHR069C(gene)|ensemblfungi:YHR069C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:0718A7ABF42E9B9B	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:ZgBS9xjR7jC96sAb0m63ElPvM7M559292	rigid:jWZfd7kvzfPOo2l+CAtdF3+8Quk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53859	uniprotkb:Q12149	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1782|uniprotkb:Q6B280|uniprotkb:D6W267|ensemblfungi:YOR001W	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:rrp6_yeast(display_long)|uniprotkb:RRP6(gene name)|psi-mi:RRP6(display_short)|uniprotkb:UNC733(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 6(gene name synonym)|uniprotkb:YOR001W(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114622|imex:IM-23146-1|dip:DIP-197202E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	refseq:NP_014643.1|sgd:S000005527|dip:DIP-4560N|ensemblfungi:YOR001W(gene)|ensemblfungi:YOR001W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0071028"(nuclear mRNA surveillance)|mint:Q12149|go:"GO:0071033"|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|rcsb pdb:1M0Y|rcsb pdb:2HBJ|rcsb pdb:2HBK|rcsb pdb:2HBL|rcsb pdb:2HBM|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:4WFC|rcsb pdb:4WFD|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5C0Y|rcsb pdb:5K36|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:B19A0B2ED74C6DA7	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:29oQaOEcqYSzOIn7B6hj29GvisU559292	rigid:jWZfd7kvzfPOo2l+CAtdF3+8Quk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y3B2	uniprotkb:Q13868	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	intact:EBI-301735|uniprotkb:Q9NUY4|uniprotkb:A3KFL3|ensembl:ENSP00000361433|uniprotkb:A3KFL4|uniprotkb:B4DKK6	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:exos2_human(display_long)|uniprotkb:EXOSC2(gene name)|psi-mi:EXOSC2(display_short)|uniprotkb:RRP4(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosome component 2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114647|imex:IM-23146-2|dip:DIP-197203E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	refseq:NP_055100.2|ensembl:ENSG00000130713(gene)|ensembl:ENST00000372358(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|mint:Q13868|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001269638.1|dip:DIP-31264N|refseq:NP_001269637.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	rogid:Lpl4OBbEYV2DRbYzLCPvbQdtaro9606	rigid:gJFmadzYDSM16dPxXDFCja1fdkc	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9Y3B2	uniprotkb:Q9NQT5	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114647|imex:IM-23146-2|dip:DIP-197203E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	rigid:gJFmadzYDSM16dPxXDFCja1fdkc	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9Y3B2	uniprotkb:Q9NPD3	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	intact:EBI-371823|ensembl:ENSP00000315476	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114647|imex:IM-23146-2|dip:DIP-197203E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606	rigid:gJFmadzYDSM16dPxXDFCja1fdkc	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9Y3B2	uniprotkb:Q9NQT4	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114647|imex:IM-23146-2|dip:DIP-197203E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606	rigid:gJFmadzYDSM16dPxXDFCja1fdkc	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9Y3B2	uniprotkb:Q5RKV6	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	intact:EBI-2841747|ensembl:ENSP00000398597	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:exos6_human(display_long)|uniprotkb:EXOSC6(gene name)|psi-mi:EXOSC6(display_short)|uniprotkb:MTR3(gene name synonym)|uniprotkb:Exosome component 6(gene name synonym)|uniprotkb:mRNA transport regulator 3 homolog(gene name synonym)|uniprotkb:p11(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114647|imex:IM-23146-2|dip:DIP-197203E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	refseq:NP_478126.1|ensembl:ENSG00000223496(gene)|ensembl:ENST00000435634(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q5RKV6|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-61038N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	rogid:tHH05GXmmH4GgRjtChjaGSLJ7Cc9606	rigid:gJFmadzYDSM16dPxXDFCja1fdkc	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9Y3B2	uniprotkb:Q15024	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114647|imex:IM-23146-2|dip:DIP-197203E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606	rigid:gJFmadzYDSM16dPxXDFCja1fdkc	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9Y3B2	uniprotkb:Q96B26	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114647|imex:IM-23146-2|dip:DIP-197203E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	rogid:y/cReHiPMubzNruyETohBjbRick9606	rigid:gJFmadzYDSM16dPxXDFCja1fdkc	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9Y3B2	uniprotkb:Q06265	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	intact:EBI-347966|ensembl:ENSP00000243498|uniprotkb:Q12883|uniprotkb:Q86Y41|uniprotkb:Q86Y48|uniprotkb:Q4W5P5	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:exos9_human(display_long)|uniprotkb:EXOSC9(gene name)|psi-mi:EXOSC9(display_short)|uniprotkb:PMSCL1(gene name synonym)|uniprotkb:Exosome component 9(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Autoantigen PM/Scl 1(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 75 kDa(gene name synonym)|uniprotkb:P75 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114647|imex:IM-23146-2|dip:DIP-197203E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006955"(immune response)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|mint:Q06265|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|ensembl:ENSG00000123737(gene)|ensembl:ENST00000243498(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|refseq:NP_001029366.1|refseq:NP_005024.2|dip:DIP-31286N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	rogid:COzGZISdlfGlht1FhyxPhzbV9hY9606	rigid:gJFmadzYDSM16dPxXDFCja1fdkc	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9Y3B2	uniprotkb:Q01780	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114647|imex:IM-23146-2|dip:DIP-197203E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606	rigid:gJFmadzYDSM16dPxXDFCja1fdkc	false	-	sufficient binding region:180-804	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P53859	uniprotkb:P48240	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1749|uniprotkb:D6VUT8|ensemblfungi:YGR158C	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:mtr3_yeast(display_long)|uniprotkb:MTR3(gene name)|psi-mi:MTR3(display_short)|uniprotkb:YGR158C(locus name)|uniprotkb:G6676(orf name)|uniprotkb:mRNA transport regulator 3(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114674|imex:IM-23146-3|dip:DIP-190934E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	sgd:S000003390|refseq:NP_011674.3|dip:DIP-931N|mint:P48240|ensemblfungi:YGR158C(gene)|ensemblfungi:YGR158C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:2FA07ABB4A1115E0	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:t5M0E3avqoJ0dbM51kE3fZlz2pc559292	rigid:gEcK7RnXjm4FAICNXipvgPU8Sak	false	-	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P53859	uniprotkb:Q08285	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1831|ensemblfungi:YOL142W|uniprotkb:D6W1S7|uniprotkb:E9P8Z4	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:rrp40_yeast(display_long)|uniprotkb:RRP40(gene name)|psi-mi:RRP40(display_short)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:YOL142W(locus name)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114674|imex:IM-23146-3|dip:DIP-190934E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	refseq:NP_014499.2|sgd:S000005502|ensemblfungi:YOL142W(gene)|ensemblfungi:YOL142W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030145"(manganese ion binding)|dip:DIP-5330N|mint:Q08285|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|interpro:IPR041054|rcsb pdb:2JA9|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:62B3A30348BBAA7C	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:3sdpWE2qP6cVgcD2b8VDWV0ox4g559292	rigid:gEcK7RnXjm4FAICNXipvgPU8Sak	false	-	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P53859	uniprotkb:P46948	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114674|imex:IM-23146-3|dip:DIP-190934E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:C80EFFB528A43044	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	rigid:gEcK7RnXjm4FAICNXipvgPU8Sak	false	-	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P53859	uniprotkb:Q12277	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1765|uniprotkb:D6VRN9|ensemblfungi:YDL111C	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:rrp42_yeast(display_long)|uniprotkb:RRP42(gene name)|psi-mi:RRP42(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:YDL111C(locus name)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114674|imex:IM-23146-3|dip:DIP-190934E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	refseq:NP_010172.1|sgd:S000002269|dip:DIP-1463N|mint:Q12277|ensemblfungi:YDL111C(gene)|ensemblfungi:YDL111C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:806C60979642C67E	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:OVyAr6b3ECMjQj3nUsuxXZqxt1o559292	rigid:gEcK7RnXjm4FAICNXipvgPU8Sak	false	-	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P53859	uniprotkb:P25359	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1773|uniprotkb:Q8NKJ5|ensemblfungi:YCR035C|uniprotkb:D6VR45	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:rrp43_yeast(display_long)|uniprotkb:RRP43(gene name)|psi-mi:RRP43(display_short)|uniprotkb:YCR035C(locus name)|uniprotkb:YCR35C(orf name)|uniprotkb:YCR522(orf name)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114674|imex:IM-23146-3|dip:DIP-190934E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	ensemblfungi:YCR035C(gene)|ensemblfungi:YCR035C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016072"(rRNA metabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|refseq:NP_009964.2|sgd:S000000631|dip:DIP-5485N|mint:P25359|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:8801837B8184134D	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:htGDTlKKMq7OdwcfGUKgfWCjJ1k559292	rigid:gEcK7RnXjm4FAICNXipvgPU8Sak	false	-	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P53859	uniprotkb:Q08162	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1740|uniprotkb:D6W244|ensemblfungi:YOL021C	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:rrp44_yeast(display_long)|uniprotkb:DIS3(gene name)|psi-mi:DIS3(display_short)|uniprotkb:Ribosomal RNA-processing protein 44(gene name synonym)|uniprotkb:Chromosome disjunction protein 3(gene name synonym)|uniprotkb:RRP44(gene name synonym)|uniprotkb:O2197(orf name)|uniprotkb:YOL021C(locus name)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114674|imex:IM-23146-3|dip:DIP-190934E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	sgd:S000005381|refseq:NP_014621.1|dip:DIP-2355N|mint:Q08162|ensemblfungi:YOL021C(gene)|ensemblfungi:YOL021C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR003029(S1, RNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR022967|interpro:IPR029060|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|rcsb pdb:2VNU|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:00DD31BD2D6904F4	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:YpToZNRenOPYsPJdGKEWBLsc4zA559292	rigid:gEcK7RnXjm4FAICNXipvgPU8Sak	false	-	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P53859	uniprotkb:Q05636	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1810|uniprotkb:D6VSR0|ensemblfungi:YDR280W	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:rrp45_yeast(display_long)|uniprotkb:RRP45(gene name)|psi-mi:RRP45(display_short)|uniprotkb:YDR280W(locus name)|uniprotkb:D9954.1(orf name)|uniprotkb:Ribosomal RNA-processing protein 45(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114674|imex:IM-23146-3|dip:DIP-190934E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	refseq:NP_010566.1|sgd:S000002688|dip:DIP-2084N|mint:Q05636|ensemblfungi:YDR280W(gene)|ensemblfungi:YDR280W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:65C9DB5A63678F2D	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:LCdt9Nm8j2AD6iecBI2CGCrhEhQ559292	rigid:gEcK7RnXjm4FAICNXipvgPU8Sak	false	-	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P53859	uniprotkb:P53256	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1842|uniprotkb:Q6TQU1|uniprotkb:D6VUM7|ensemblfungi:YGR095C	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:rrp46_yeast(display_long)|uniprotkb:RRP46(gene name)|psi-mi:RRP46(display_short)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:YGR095C(locus name)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114674|imex:IM-23146-3|dip:DIP-190934E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	refseq:NP_011609.2|sgd:S000003327|dip:DIP-6838N|mint:P53256|ensemblfungi:YGR095C(gene)|ensemblfungi:YGR095C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:F1307E0EE4FC3133	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:2ESxObCiXUjTEvlB5ow7eCgivz0559292	rigid:gEcK7RnXjm4FAICNXipvgPU8Sak	false	-	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P53859	uniprotkb:P38792	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1757|uniprotkb:D3DL18|ensemblfungi:YHR069C	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:rrp4_yeast(display_long)|uniprotkb:RRP4(gene name)|psi-mi:RRP4(display_short)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:YHR069C(locus name)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114674|imex:IM-23146-3|dip:DIP-190934E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	refseq:NP_011936.1|sgd:S000001111|dip:DIP-5888N|mint:P38792|ensemblfungi:YHR069C(gene)|ensemblfungi:YHR069C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:0718A7ABF42E9B9B	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:ZgBS9xjR7jC96sAb0m63ElPvM7M559292	rigid:gEcK7RnXjm4FAICNXipvgPU8Sak	false	-	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P53859	uniprotkb:Q12149	intact:EBI-1731|uniprotkb:D6W0W0|ensemblfungi:YNL232W	intact:EBI-1782|uniprotkb:Q6B280|uniprotkb:D6W267|ensemblfungi:YOR001W	psi-mi:csl4_yeast(display_long)|uniprotkb:CSL4(gene name)|psi-mi:CSL4(display_short)|uniprotkb:YNL232W(locus name)|uniprotkb:N1154(orf name)|uniprotkb:SKI4(gene name synonym)|uniprotkb:CEP1 synthetic lethal protein 4(gene name synonym)	psi-mi:rrp6_yeast(display_long)|uniprotkb:RRP6(gene name)|psi-mi:RRP6(display_short)|uniprotkb:UNC733(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 6(gene name synonym)|uniprotkb:YOR001W(locus name)	psi-mi:"MI:0071"(molecular sieving)	Wasmuth et al. (2014)	pubmed:25043052|doi:10.1038/nature13406|imex:IM-23146	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114674|imex:IM-23146-3|dip:DIP-190934E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005176|refseq:NP_014167.1|dip:DIP-6785N|mint:P53859|ensemblfungi:YNL232W(gene)|ensemblfungi:YNL232W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0043628"(ncRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR039771|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	refseq:NP_014643.1|sgd:S000005527|dip:DIP-4560N|ensemblfungi:YOR001W(gene)|ensemblfungi:YOR001W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0071028"(nuclear mRNA surveillance)|mint:Q12149|go:"GO:0071033"|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|rcsb pdb:1M0Y|rcsb pdb:2HBJ|rcsb pdb:2HBK|rcsb pdb:2HBL|rcsb pdb:2HBM|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:4WFC|rcsb pdb:4WFD|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5C0Y|rcsb pdb:5K36|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|reactome:R-SCE-6791226	psi-mi:"MI:0465"(dip)	crc64:52D3416EA183583B	crc64:B19A0B2ED74C6DA7	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:pXrzOxfgb4fz6zCg/ZX8/gNjTvE559292	rogid:29oQaOEcqYSzOIn7B6hj29GvisU559292	rigid:gEcK7RnXjm4FAICNXipvgPU8Sak	false	-	sufficient binding region:128-733	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)