#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P17870	uniprotkb:P49951	intact:EBI-16114176|ensembl:ENSBTAP00000042435	intact:EBI-448355|ensembl:ENSBTAP00000060092	psi-mi:arrb1_bovin(display_long)|uniprotkb:ARRB1(gene name)|psi-mi:ARRB1(display_short)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:Arrestin-2(gene name synonym)	psi-mi:clh1_bovin(display_long)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)	psi-mi:"MI:0096"(pull down)	Shukla et al. (2014)	pubmed:25043026|doi:10.1038/nature13430|imex:IM-23135	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16114254|imex:IM-23135-1|dip:DIP-197193E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSBTAG00000020485(gene)|ensembl:ENSBTAT00000045006(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002029"(desensitization of G protein-coupled receptor signaling pathway)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030276"(clathrin binding)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|rcsb pdb:1G4M|rcsb pdb:1G4R|rcsb pdb:1JSY|rcsb pdb:1ZSH|rcsb pdb:2WTR|rcsb pdb:3GC3|rcsb pdb:3GD1|rcsb pdb:6NI2|refseq:NP_776668.1|dip:DIP-61028N	refseq:NP_776448.1|dip:DIP-31603N|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:P49951|rcsb pdb:1B89|rcsb pdb:1UTC|rcsb pdb:1XI4|rcsb pdb:1XI5|rcsb pdb:3GC3|rcsb pdb:3GD1|rcsb pdb:3IYV|rcsb pdb:3LVH|rcsb pdb:3QIL|rcsb pdb:5M5R|rcsb pdb:5M5S|rcsb pdb:5M5T|rcsb pdb:5M5U|rcsb pdb:5M5V|rcsb pdb:5M61|rcsb pdb:6WCJ|rcsb pdb:3LVG|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|ensembl:ENSBTAG00000016708(gene)|ensembl:ENSBTAT00000077192(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:yl3xQ7LTHgNWlD3XPgYCzxZJIKk9913	rogid:wpLSa4t2I+sHqUBOftWeW3eCayU9913	rigid:A/SyJFwcdRyQtFX7qxoZzyW7tPA	false	sufficient binding region:1-393	sufficient binding region:1-363|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)