#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:A7XY94 uniprotkb:A0A1L8F5J9 intact:EBI-16113306 intact:EBI-15932423|uniprotkb:Q91805|intact:EBI-16113290|uniprotkb:C0KD15|uniprotkb:C0KD16|uniprotkb:C0KD17|uniprotkb:C0KD18|uniprotkb:C0KD19|uniprotkb:Q4PLR7|uniprotkb:Q91977 psi-mi:nmde2_xenla(display_long)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym)|uniprotkb:grin2b(gene name)|psi-mi:grin2b(display_short) psi-mi:nmdz1_xenla(display_long)|uniprotkb:N-methyl-D-aspartate receptor subunit NR1(gene name synonym)|uniprotkb:grin1(gene name)|psi-mi:grin1(display_short) psi-mi:"MI:0096"(pull down) Lee et al. (2014) pubmed:25008524|doi:10.1038/nature13548|imex:IM-23145 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16113339|imex:IM-23145-1|dip:DIP-197201E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010043"(response to zinc ion)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:4TLL|rcsb pdb:4TLM|rcsb pdb:5IOU|rcsb pdb:5IOV|rcsb pdb:5IPQ|rcsb pdb:5IPT|rcsb pdb:5IPU|rcsb pdb:5IPV|rcsb pdb:5UN1|rcsb pdb:5UOW|rcsb pdb:5UP2|rcsb pdb:5IPR|rcsb pdb:5IPS|refseq:NP_001104191.1|refseq:XP_018114751.1|dip:DIP-61037N go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010043"(response to zinc ion)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018882|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3QEK|rcsb pdb:3QEL|rcsb pdb:3QEM|rcsb pdb:4TLL|rcsb pdb:4TLM|rcsb pdb:5B3J|rcsb pdb:5EWJ|rcsb pdb:5EWL|rcsb pdb:5EWM|rcsb pdb:5IOU|rcsb pdb:5IOV|rcsb pdb:5IPQ|rcsb pdb:5IPR|rcsb pdb:5IPS|rcsb pdb:5IPT|rcsb pdb:5IPU|rcsb pdb:5IPV|rcsb pdb:5TPW|rcsb pdb:5TPZ|rcsb pdb:5TQ0|rcsb pdb:5TQ2|rcsb pdb:5UN1|rcsb pdb:5UOW|rcsb pdb:5UP2|rcsb pdb:6E7R|rcsb pdb:6E7S|rcsb pdb:6E7T|rcsb pdb:6E7U|rcsb pdb:6E7V|rcsb pdb:6E7W|rcsb pdb:6E7X|refseq:NP_001081615.1|dip:DIP-59169N|dip:DIP-61036N|refseq:NP_001081616.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/10/30 rogid:JvmsNwEAlJeyQt1HTKbx/ZBB6b88355 rogid:daV6BmGGBjNcWZrdXtLyh8cV7Dw8355 rigid:FOlC1DJ6GVfi4g9oq0KrSQ8Ox7c false sufficient binding region:1-839|strep ii tag:c-c sufficient binding region:1-834 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A7XY94 uniprotkb:A0A1L8F5J9 intact:EBI-16113306 intact:EBI-15932423|uniprotkb:Q91805|intact:EBI-16113290|uniprotkb:C0KD15|uniprotkb:C0KD16|uniprotkb:C0KD17|uniprotkb:C0KD18|uniprotkb:C0KD19|uniprotkb:Q4PLR7|uniprotkb:Q91977 psi-mi:nmde2_xenla(display_long)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym)|uniprotkb:grin2b(gene name)|psi-mi:grin2b(display_short) psi-mi:nmdz1_xenla(display_long)|uniprotkb:N-methyl-D-aspartate receptor subunit NR1(gene name synonym)|uniprotkb:grin1(gene name)|psi-mi:grin1(display_short) psi-mi:"MI:0114"(x-ray crystallography) Lee et al. (2014) pubmed:25008524|doi:10.1038/nature13548|imex:IM-23145 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16113364|imex:IM-23145-2|dip:DIP-197201E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010043"(response to zinc ion)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:4TLL|rcsb pdb:4TLM|rcsb pdb:5IOU|rcsb pdb:5IOV|rcsb pdb:5IPQ|rcsb pdb:5IPT|rcsb pdb:5IPU|rcsb pdb:5IPV|rcsb pdb:5UN1|rcsb pdb:5UOW|rcsb pdb:5UP2|rcsb pdb:5IPR|rcsb pdb:5IPS|refseq:NP_001104191.1|refseq:XP_018114751.1|dip:DIP-61037N go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010043"(response to zinc ion)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018882|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3QEK|rcsb pdb:3QEL|rcsb pdb:3QEM|rcsb pdb:4TLL|rcsb pdb:4TLM|rcsb pdb:5B3J|rcsb pdb:5EWJ|rcsb pdb:5EWL|rcsb pdb:5EWM|rcsb pdb:5IOU|rcsb pdb:5IOV|rcsb pdb:5IPQ|rcsb pdb:5IPR|rcsb pdb:5IPS|rcsb pdb:5IPT|rcsb pdb:5IPU|rcsb pdb:5IPV|rcsb pdb:5TPW|rcsb pdb:5TPZ|rcsb pdb:5TQ0|rcsb pdb:5TQ2|rcsb pdb:5UN1|rcsb pdb:5UOW|rcsb pdb:5UP2|rcsb pdb:6E7R|rcsb pdb:6E7S|rcsb pdb:6E7T|rcsb pdb:6E7U|rcsb pdb:6E7V|rcsb pdb:6E7W|rcsb pdb:6E7X|refseq:NP_001081615.1|dip:DIP-59169N|dip:DIP-61036N|refseq:NP_001081616.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/10/30 rogid:JvmsNwEAlJeyQt1HTKbx/ZBB6b88355 rogid:daV6BmGGBjNcWZrdXtLyh8cV7Dw8355 rigid:FOlC1DJ6GVfi4g9oq0KrSQ8Ox7c false sufficient binding region:1-839 sufficient binding region:1-834 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A7XY94 uniprotkb:A0A1L8F5J9 intact:EBI-16113306 intact:EBI-15932423|uniprotkb:Q91805|intact:EBI-16113290|uniprotkb:C0KD15|uniprotkb:C0KD16|uniprotkb:C0KD17|uniprotkb:C0KD18|uniprotkb:C0KD19|uniprotkb:Q4PLR7|uniprotkb:Q91977 psi-mi:nmde2_xenla(display_long)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym)|uniprotkb:grin2b(gene name)|psi-mi:grin2b(display_short) psi-mi:nmdz1_xenla(display_long)|uniprotkb:N-methyl-D-aspartate receptor subunit NR1(gene name synonym)|uniprotkb:grin1(gene name)|psi-mi:grin1(display_short) psi-mi:"MI:0071"(molecular sieving) Lee et al. (2014) pubmed:25008524|doi:10.1038/nature13548|imex:IM-23145 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16113385|imex:IM-23145-3|dip:DIP-197201E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010043"(response to zinc ion)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:4TLL|rcsb pdb:4TLM|rcsb pdb:5IOU|rcsb pdb:5IOV|rcsb pdb:5IPQ|rcsb pdb:5IPT|rcsb pdb:5IPU|rcsb pdb:5IPV|rcsb pdb:5UN1|rcsb pdb:5UOW|rcsb pdb:5UP2|rcsb pdb:5IPR|rcsb pdb:5IPS|refseq:NP_001104191.1|refseq:XP_018114751.1|dip:DIP-61037N go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010043"(response to zinc ion)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018882|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3QEK|rcsb pdb:3QEL|rcsb pdb:3QEM|rcsb pdb:4TLL|rcsb pdb:4TLM|rcsb pdb:5B3J|rcsb pdb:5EWJ|rcsb pdb:5EWL|rcsb pdb:5EWM|rcsb pdb:5IOU|rcsb pdb:5IOV|rcsb pdb:5IPQ|rcsb pdb:5IPR|rcsb pdb:5IPS|rcsb pdb:5IPT|rcsb pdb:5IPU|rcsb pdb:5IPV|rcsb pdb:5TPW|rcsb pdb:5TPZ|rcsb pdb:5TQ0|rcsb pdb:5TQ2|rcsb pdb:5UN1|rcsb pdb:5UOW|rcsb pdb:5UP2|rcsb pdb:6E7R|rcsb pdb:6E7S|rcsb pdb:6E7T|rcsb pdb:6E7U|rcsb pdb:6E7V|rcsb pdb:6E7W|rcsb pdb:6E7X|refseq:NP_001081615.1|dip:DIP-59169N|dip:DIP-61036N|refseq:NP_001081616.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/10/30 rogid:JvmsNwEAlJeyQt1HTKbx/ZBB6b88355 rogid:daV6BmGGBjNcWZrdXtLyh8cV7Dw8355 rigid:FOlC1DJ6GVfi4g9oq0KrSQ8Ox7c false sufficient binding region:1-839 sufficient binding region:1-834 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)