#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P69681 uniprotkb:P69681 intact:EBI-9137905|uniprotkb:Q2MBX5|uniprotkb:P37905|ensemblbacteria:AAC73554|ensemblbacteria:BAE76231 intact:EBI-9137905|uniprotkb:Q2MBX5|uniprotkb:P37905|ensemblbacteria:AAC73554|ensemblbacteria:BAE76231 psi-mi:amtb_ecoli(display_long)|uniprotkb:ybaG(gene name synonym)|uniprotkb:JW0441(locus name)|uniprotkb:b0451(locus name)|uniprotkb:amtB(gene name)|psi-mi:amtB(display_short)|uniprotkb:Ammonia channel AmtB(gene name synonym)|uniprotkb:Ammonium channel AmtB(gene name synonym) psi-mi:amtb_ecoli(display_long)|uniprotkb:ybaG(gene name synonym)|uniprotkb:JW0441(locus name)|uniprotkb:b0451(locus name)|uniprotkb:amtB(gene name)|psi-mi:amtB(display_short)|uniprotkb:Ammonia channel AmtB(gene name synonym)|uniprotkb:Ammonium channel AmtB(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Laganowsky et al. (2014) pubmed:24899312|doi:"https://doi.org/10.1038/nature13419"|imex:IM-22684 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16109198|imex:IM-22684-1|dip:DIP-59371E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_414985.1|refseq:WP_000685029.1|dip:DIP-29874N|ensemblbacteria:AAC73554(transcript)|ensemblbacteria:b0451(gene)|ensemblbacteria:BAE76231(gene)|ensemblbacteria:BAE76231(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015292"(uniporter activity)|go:"GO:0015670"(carbon dioxide transport)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|go:"GO:0042802"(identical protein binding)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|rcsb pdb:1U77|rcsb pdb:1U7C|rcsb pdb:1U7G|rcsb pdb:1XQE|rcsb pdb:1XQF|rcsb pdb:2NMR|rcsb pdb:2NOP|rcsb pdb:2NOW|rcsb pdb:2NPC|rcsb pdb:2NPD|rcsb pdb:2NPE|rcsb pdb:2NPG|rcsb pdb:2NPJ|rcsb pdb:2NPK|rcsb pdb:2NS1|rcsb pdb:2NUU|rcsb pdb:3C1G|rcsb pdb:3C1H|rcsb pdb:3C1I|rcsb pdb:3C1J|rcsb pdb:6B21 refseq:NP_414985.1|refseq:WP_000685029.1|dip:DIP-29874N|ensemblbacteria:AAC73554(transcript)|ensemblbacteria:b0451(gene)|ensemblbacteria:BAE76231(gene)|ensemblbacteria:BAE76231(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015292"(uniporter activity)|go:"GO:0015670"(carbon dioxide transport)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|go:"GO:0042802"(identical protein binding)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|rcsb pdb:1U77|rcsb pdb:1U7C|rcsb pdb:1U7G|rcsb pdb:1XQE|rcsb pdb:1XQF|rcsb pdb:2NMR|rcsb pdb:2NOP|rcsb pdb:2NOW|rcsb pdb:2NPC|rcsb pdb:2NPD|rcsb pdb:2NPE|rcsb pdb:2NPG|rcsb pdb:2NPJ|rcsb pdb:2NPK|rcsb pdb:2NS1|rcsb pdb:2NUU|rcsb pdb:3C1G|rcsb pdb:3C1H|rcsb pdb:3C1I|rcsb pdb:3C1J|rcsb pdb:6B21 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:rxUrZ8mKTnfeFp2kgespn5DBqsg83333 rogid:rxUrZ8mKTnfeFp2kgespn5DBqsg83333 rigid:Yjue5geHQTic+XEzILnRuepuS7k false sufficient binding region:26-428 sufficient binding region:26-428 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60844 uniprotkb:P60844 intact:EBI-957663|ensemblbacteria:AAC73962|ensemblbacteria:BAA35589|uniprotkb:P48838|uniprotkb:P75827|uniprotkb:Q47159 intact:EBI-957663|ensemblbacteria:AAC73962|ensemblbacteria:BAA35589|uniprotkb:P48838|uniprotkb:P75827|uniprotkb:Q47159 psi-mi:aqpz_ecoli(display_long)|uniprotkb:aqpZ(gene name)|psi-mi:aqpZ(display_short)|uniprotkb:bniP(gene name synonym)|uniprotkb:b0875(locus name)|uniprotkb:Bacterial nodulin-like intrinsic protein(gene name synonym)|uniprotkb:JW0859(locus name) psi-mi:aqpz_ecoli(display_long)|uniprotkb:aqpZ(gene name)|psi-mi:aqpZ(display_short)|uniprotkb:bniP(gene name synonym)|uniprotkb:b0875(locus name)|uniprotkb:Bacterial nodulin-like intrinsic protein(gene name synonym)|uniprotkb:JW0859(locus name) psi-mi:"MI:1246"(ion mobility mass spectrometry of complexes) Laganowsky et al. (2014) pubmed:24899312|doi:"https://doi.org/10.1038/nature13419"|imex:IM-22684 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16109232|imex:IM-22684-3|dip:DIP-64320E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC73962(transcript)|ensemblbacteria:b0875(gene)|ensemblbacteria:BAA35589(gene)|ensemblbacteria:BAA35589(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0015250"(water channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|interpro:IPR023743|interpro:IPR034294|rcsb pdb:1RC2|refseq:NP_415396.1|rcsb pdb:2ABM|rcsb pdb:2O9D|rcsb pdb:2O9E|rcsb pdb:2O9F|rcsb pdb:2O9G|rcsb pdb:3NK5|rcsb pdb:3NKA|rcsb pdb:3NKC|refseq:WP_001298299.1|dip:DIP-35499N ensemblbacteria:AAC73962(transcript)|ensemblbacteria:b0875(gene)|ensemblbacteria:BAA35589(gene)|ensemblbacteria:BAA35589(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0015250"(water channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|interpro:IPR023743|interpro:IPR034294|rcsb pdb:1RC2|refseq:NP_415396.1|rcsb pdb:2ABM|rcsb pdb:2O9D|rcsb pdb:2O9E|rcsb pdb:2O9F|rcsb pdb:2O9G|rcsb pdb:3NK5|rcsb pdb:3NKA|rcsb pdb:3NKC|refseq:WP_001298299.1|dip:DIP-35499N psi-mi:"MI:0465"(dip) crc64:3BDE1A932D45CF14 crc64:3BDE1A932D45CF14 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:htNjpAsjLN7RJlavmocw/xJX8Lg83333 rogid:htNjpAsjLN7RJlavmocw/xJX8Lg83333 rigid:DFhADD7wAsXZM3+zNv8SjhlAzUc false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P69681 uniprotkb:P69681 intact:EBI-9137905|uniprotkb:Q2MBX5|uniprotkb:P37905|ensemblbacteria:AAC73554|ensemblbacteria:BAE76231 intact:EBI-9137905|uniprotkb:Q2MBX5|uniprotkb:P37905|ensemblbacteria:AAC73554|ensemblbacteria:BAE76231 psi-mi:amtb_ecoli(display_long)|uniprotkb:ybaG(gene name synonym)|uniprotkb:JW0441(locus name)|uniprotkb:b0451(locus name)|uniprotkb:amtB(gene name)|psi-mi:amtB(display_short)|uniprotkb:Ammonia channel AmtB(gene name synonym)|uniprotkb:Ammonium channel AmtB(gene name synonym) psi-mi:amtb_ecoli(display_long)|uniprotkb:ybaG(gene name synonym)|uniprotkb:JW0441(locus name)|uniprotkb:b0451(locus name)|uniprotkb:amtB(gene name)|psi-mi:amtB(display_short)|uniprotkb:Ammonia channel AmtB(gene name synonym)|uniprotkb:Ammonium channel AmtB(gene name synonym) psi-mi:"MI:1246"(ion mobility mass spectrometry of complexes) Laganowsky et al. (2014) pubmed:24899312|doi:"https://doi.org/10.1038/nature13419"|imex:IM-22684 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16109216|imex:IM-22684-2|dip:DIP-59371E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_414985.1|refseq:WP_000685029.1|dip:DIP-29874N|ensemblbacteria:AAC73554(transcript)|ensemblbacteria:b0451(gene)|ensemblbacteria:BAE76231(gene)|ensemblbacteria:BAE76231(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015292"(uniporter activity)|go:"GO:0015670"(carbon dioxide transport)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|go:"GO:0042802"(identical protein binding)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|rcsb pdb:1U77|rcsb pdb:1U7C|rcsb pdb:1U7G|rcsb pdb:1XQE|rcsb pdb:1XQF|rcsb pdb:2NMR|rcsb pdb:2NOP|rcsb pdb:2NOW|rcsb pdb:2NPC|rcsb pdb:2NPD|rcsb pdb:2NPE|rcsb pdb:2NPG|rcsb pdb:2NPJ|rcsb pdb:2NPK|rcsb pdb:2NS1|rcsb pdb:2NUU|rcsb pdb:3C1G|rcsb pdb:3C1H|rcsb pdb:3C1I|rcsb pdb:3C1J|rcsb pdb:6B21 refseq:NP_414985.1|refseq:WP_000685029.1|dip:DIP-29874N|ensemblbacteria:AAC73554(transcript)|ensemblbacteria:b0451(gene)|ensemblbacteria:BAE76231(gene)|ensemblbacteria:BAE76231(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015292"(uniporter activity)|go:"GO:0015670"(carbon dioxide transport)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|go:"GO:0042802"(identical protein binding)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|rcsb pdb:1U77|rcsb pdb:1U7C|rcsb pdb:1U7G|rcsb pdb:1XQE|rcsb pdb:1XQF|rcsb pdb:2NMR|rcsb pdb:2NOP|rcsb pdb:2NOW|rcsb pdb:2NPC|rcsb pdb:2NPD|rcsb pdb:2NPE|rcsb pdb:2NPG|rcsb pdb:2NPJ|rcsb pdb:2NPK|rcsb pdb:2NS1|rcsb pdb:2NUU|rcsb pdb:3C1G|rcsb pdb:3C1H|rcsb pdb:3C1I|rcsb pdb:3C1J|rcsb pdb:6B21 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:rxUrZ8mKTnfeFp2kgespn5DBqsg83333 rogid:rxUrZ8mKTnfeFp2kgespn5DBqsg83333 rigid:Yjue5geHQTic+XEzILnRuepuS7k false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WJN5 uniprotkb:P9WJN5 intact:EBI-15799854|uniprotkb:L0T5D5|uniprotkb:O53898|uniprotkb:P0A5K8 intact:EBI-15799854|uniprotkb:L0T5D5|uniprotkb:O53898|uniprotkb:P0A5K8 psi-mi:mscl_myctu(display_long)|uniprotkb:mscL(gene name)|psi-mi:mscL(display_short)|uniprotkb:MTV044.13c(orf name)|uniprotkb:Rv0985c(locus name) psi-mi:mscl_myctu(display_long)|uniprotkb:mscL(gene name)|psi-mi:mscL(display_short)|uniprotkb:MTV044.13c(orf name)|uniprotkb:Rv0985c(locus name) psi-mi:"MI:1246"(ion mobility mass spectrometry of complexes) Laganowsky et al. (2014) pubmed:24899312|doi:"https://doi.org/10.1038/nature13419"|imex:IM-22684 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16109248|imex:IM-22684-4|dip:DIP-187520E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022836"(gated channel activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0055085"(transmembrane transport)|rcsb pdb:6CTD|interpro:IPR037673|rcsb pdb:2OAR|interpro:IPR001185(Large-conductance mechanosensitive channel)|interpro:IPR019823|refseq:NP_215500.1|refseq:WP_003405128.1|interpro:IPR036019 go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022836"(gated channel activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0055085"(transmembrane transport)|rcsb pdb:6CTD|interpro:IPR037673|rcsb pdb:2OAR|interpro:IPR001185(Large-conductance mechanosensitive channel)|interpro:IPR019823|refseq:NP_215500.1|refseq:WP_003405128.1|interpro:IPR036019 psi-mi:"MI:0465"(dip) crc64:D682D3F2C1651E9C crc64:D682D3F2C1651E9C full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:adJwRmBmIrHHrRg3lJ/a8Fd/r9083332 rogid:adJwRmBmIrHHrRg3lJ/a8Fd/r9083332 rigid:rwxbAi33VjTLCLJJLefuhH7MzDw false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)