#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8IXI2 intact:EBI-4399559 intact:EBI-1396430|uniprotkb:A4FVB6|uniprotkb:Q6NUR3|uniprotkb:Q6P9F8|uniprotkb:Q6PJG1|uniprotkb:Q6YMW8|uniprotkb:Q86UB0|uniprotkb:Q8IW28|uniprotkb:Q8IXJ7|uniprotkb:Q9H067|uniprotkb:Q9H9N8|uniprotkb:Q9NUZ2|uniprotkb:A6NFV0|uniprotkb:B4DG48|uniprotkb:J9JIH9|ensembl:ENSP00000334724 dip:DIP-24261N psi-mi:miro1_human(display_long)|uniprotkb:Ras homolog gene family member T1(gene name synonym)|uniprotkb:Rac-GTP-binding protein-like protein(gene name synonym)|uniprotkb:RHOT1(gene name)|psi-mi:RHOT1(display_short)|uniprotkb:ARHT1(gene name synonym) psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bingol et al. (2014) pubmed:24896179|doi:10.1038/nature13418|imex:IM-22688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16109070|imex:IM-22688-1|dip:DIP-196543E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001028738.1|refseq:NP_001028740.1|refseq:NP_060777.3|refseq:NP_001028739.2|refseq:NP_001275683.1|refseq:NP_001275684.1|refseq:NP_001275687.1|dip:DIP-39114N|ensembl:ENSG00000126858(gene)|ensembl:ENST00000333942(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034640"(establishment of mitochondrion localization by microtubule attachment)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1902513"(regulation of organelle transport along microtubule)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR013566(EF hand associated, type-1)|interpro:IPR013567(EF hand associated, type-2)|interpro:IPR018247|interpro:IPR020860|interpro:IPR021181|interpro:IPR027417|interpro:IPR029506|mint:Q8IXI2|rcsb pdb:5KSO|rcsb pdb:5KSP|rcsb pdb:5KSY|rcsb pdb:5KSZ|rcsb pdb:5KTY|rcsb pdb:5KU1|rcsb pdb:6D71|reactome:R-HSA-5689880|reactome:R-HSA-9013425 uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 psi-mi:"MI:0465"(dip) - no-uniprot-update: full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/15 rogid:gA6A8bgSwshvMwCO0cG66h+wwIY9606 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rigid:brmA6ZnzsGkpywRwvOqC20K12dw false - ha tag:0-0 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q15388 intact:EBI-4399559 intact:EBI-711636|uniprotkb:A8K195|uniprotkb:Q498B3|uniprotkb:Q6IBT4|ensembl:ENSP00000355566 dip:DIP-24261N psi-mi:tom20_human(display_long)|uniprotkb:Outer mitochondrial membrane receptor Tom20(gene name synonym)|uniprotkb:TOMM20(gene name)|psi-mi:TOMM20(display_short)|uniprotkb:KIAA0016(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym) psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bingol et al. (2014) pubmed:24896179|doi:10.1038/nature13418|imex:IM-22688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16109115|imex:IM-22688-3|dip:DIP-196544E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055580.1|dip:DIP-46735N|ensembl:ENSG00000173726(gene)|ensembl:ENST00000366607(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905242"(response to 3,3',5-triiodo-L-thyronine)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR022422|interpro:IPR023392|rcsb pdb:4APO|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880 uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 psi-mi:"MI:0465"(dip) - no-uniprot-update: full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/15 rogid:+wNh1qTU0NtgQekYJjhfj6O3UoA9606 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rigid:JCDD5sbvW728rh0ZeXsQ/kaO5Es false - ha tag:0-0 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q15388 intact:EBI-4399559 intact:EBI-711636|uniprotkb:A8K195|uniprotkb:Q498B3|uniprotkb:Q6IBT4|ensembl:ENSP00000355566 dip:DIP-24261N psi-mi:tom20_human(display_long)|uniprotkb:Outer mitochondrial membrane receptor Tom20(gene name synonym)|uniprotkb:TOMM20(gene name)|psi-mi:TOMM20(display_short)|uniprotkb:KIAA0016(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym) psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bingol et al. (2014) pubmed:24896179|doi:10.1038/nature13418|imex:IM-22688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16109089|imex:IM-22688-2|dip:DIP-196544E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055580.1|dip:DIP-46735N|ensembl:ENSG00000173726(gene)|ensembl:ENST00000366607(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905242"(response to 3,3',5-triiodo-L-thyronine)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR022422|interpro:IPR023392|rcsb pdb:4APO|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880 uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 psi-mi:"MI:0465"(dip) - no-uniprot-update: full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/15 rogid:+wNh1qTU0NtgQekYJjhfj6O3UoA9606 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rigid:JCDD5sbvW728rh0ZeXsQ/kaO5Es false myc tag:c-c|mutation disrupting interaction strength:68-68,61-61,56-56 ha tag:0-0 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q70CQ3 intact:EBI-4399559 intact:EBI-2512374|ensembl:ENSP00000257548|uniprotkb:Q9BSS3|uniprotkb:Q96JX4|uniprotkb:Q8WTU7 dip:DIP-24261N psi-mi:ubp30_human(display_long)|uniprotkb:USP30(gene name)|psi-mi:USP30(display_short)|uniprotkb:Ubiquitin-specific-processing protease 30(gene name synonym)|uniprotkb:Deubiquitinating enzyme 30(gene name synonym)|uniprotkb:Ubiquitin thioesterase 30(gene name synonym) psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bingol et al. (2014) pubmed:24896179|doi:10.1038/nature13418|imex:IM-22688 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16109134|imex:IM-22688-4|dip:DIP-196545E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000135093(gene)|ensembl:ENST00000257548(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000425"(pexophagy)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035871"(protein K11-linked deubiquitination)|go:"GO:0044313"(protein K6-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901525"(negative regulation of mitophagy)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|rcsb pdb:5OHK|rcsb pdb:5OHN|rcsb pdb:5OHP|reactome:R-HSA-5689880|reactome:R-HSA-9664873|refseq:NP_001288104.1|refseq:NP_116052.2|refseq:XP_006719716.1|dip:DIP-53578N uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 psi-mi:"MI:0465"(dip) - no-uniprot-update: full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/08 2017/08/15 rogid:KWb+QBK14roR0XS+MQNdf60cO4w9606 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rigid:JKhd/fksuTY+4S1JZNeHGL+xQjc false - ha tag:0-0 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)