#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O60260	intact:EBI-4399559	intact:EBI-716346|uniprotkb:A3FG77|uniprotkb:Q5TFV8|uniprotkb:Q6Q2I6|uniprotkb:Q8NI41|uniprotkb:Q8NI43|uniprotkb:Q8NI44|uniprotkb:D3JZW7|uniprotkb:D3K2X0|uniprotkb:Q5VVX4|uniprotkb:Q8WW07|uniprotkb:A8K975|ensembl:ENSP00000355865	dip:DIP-24261N	psi-mi:prkn_human(display_long)|uniprotkb:PRKN(gene name)|psi-mi:PRKN(display_short)|uniprotkb:PARK2(gene name synonym)|uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)|uniprotkb:Parkinson juvenile disease protein 2(gene name synonym)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:"MI:0808"(comigration in sds page)	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16107276|imex:IM-23108-3|dip:DIP-197140E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004553.2|refseq:NP_054642.2|refseq:NP_054643.2|ensembl:ENSG00000185345(gene)|ensembl:ENST00000366898(transcript)|go:"GO:0097602"(cullin family protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0098793"(presynapse)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902254"(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:1905281"(positive regulation of retrograde transport, endosome to Golgi)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|mint:O60260|rcsb pdb:1IYF|rcsb pdb:2JMO|rcsb pdb:4BM9|rcsb pdb:4I1F|rcsb pdb:4I1H|rcsb pdb:5C1Z|rcsb pdb:5C23|rcsb pdb:5C9V|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5TR5|rcsb pdb:6GLC|rcsb pdb:6HUE|rcsb pdb:6N13|reactome:R-HSA-5205685|reactome:R-HSA-5689877|reactome:R-HSA-9646399|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001964"(startle response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032368"(regulation of lipid transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051582"(positive regulation of neurotransmitter uptake)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055069"(zinc ion homeostasis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097413"(Lewy body)|dip:DIP-37655N	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	psi-mi:"MI:0465"(dip)	-	no-uniprot-update:	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/15	rogid:KbbW8SMJIWwQvR4lvsKyi25NRUw9606	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rigid:lyDsN/LOkJuzn2X38JAAxKozptE	false	sufficient binding region:77-465	his tag:0-0	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q99PZ6	uniprotkb:P68036-1	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9|ensemblbacteria:AAL72314	intact:EBI-15556257|ensembl:ENSP00000344259	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:p68036-1(display_long)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16107256|imex:IM-23108-2|dip:DIP-197137E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:YP_009062537.1|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|ensemblbacteria:AAL72314(transcript)|ensemblbacteria:SF_p0227(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0016301"(kinase activity)|go:"GO:0043657"(host cell)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:4BVU	ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|intact:EBI-711173(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/15	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	rigid:n2bGHEoz8sWoDjd4z1DCNfmxgwg	false	sufficient binding region:26-196	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99PZ6	intact:EBI-4399559	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9|ensemblbacteria:AAL72314	dip:DIP-24261N	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16107256|imex:IM-23108-2|dip:DIP-197137E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:YP_009062537.1|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|ensemblbacteria:AAL72314(transcript)|ensemblbacteria:SF_p0227(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0016301"(kinase activity)|go:"GO:0043657"(host cell)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:4BVU	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	psi-mi:"MI:0465"(dip)	-	no-uniprot-update:	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/15	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rigid:n2bGHEoz8sWoDjd4z1DCNfmxgwg	false	sufficient binding region:26-196	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99PZ6	uniprotkb:P68036-1	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9|ensemblbacteria:AAL72314	intact:EBI-15556257|ensembl:ENSP00000344259	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:p68036-1(display_long)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16107237|imex:IM-23108-1|dip:DIP-197139E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:YP_009062537.1|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|ensemblbacteria:AAL72314(transcript)|ensemblbacteria:SF_p0227(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0016301"(kinase activity)|go:"GO:0043657"(host cell)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:4BVU	ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|intact:EBI-711173(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	rigid:D3ifyt2VNfFOazL+qfypeuhGmkc	false	sufficient binding region:26-196	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99PZ6	uniprotkb:P68036-1	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9|ensemblbacteria:AAL72314	intact:EBI-15556257|ensembl:ENSP00000344259	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:p68036-1(display_long)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16107338|imex:IM-23108-6|dip:DIP-197137E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:YP_009062537.1|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|ensemblbacteria:AAL72314(transcript)|ensemblbacteria:SF_p0227(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0016301"(kinase activity)|go:"GO:0043657"(host cell)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:4BVU	ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|intact:EBI-711173(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/15	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	rigid:n2bGHEoz8sWoDjd4z1DCNfmxgwg	false	sufficient binding region:26-196	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99PZ6	intact:EBI-4399559	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9|ensemblbacteria:AAL72314	dip:DIP-24261N	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16107338|imex:IM-23108-6|dip:DIP-197137E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:YP_009062537.1|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|ensemblbacteria:AAL72314(transcript)|ensemblbacteria:SF_p0227(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0016301"(kinase activity)|go:"GO:0043657"(host cell)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:4BVU	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	psi-mi:"MI:0465"(dip)	-	no-uniprot-update:	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/15	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rigid:n2bGHEoz8sWoDjd4z1DCNfmxgwg	false	sufficient binding region:26-196	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99PZ6	intact:EBI-4399559	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9|ensemblbacteria:AAL72314	dip:DIP-24261N	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16107317|imex:IM-23108-5|dip:DIP-197138E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:YP_009062537.1|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|ensemblbacteria:AAL72314(transcript)|ensemblbacteria:SF_p0227(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0016301"(kinase activity)|go:"GO:0043657"(host cell)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:4BVU	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	psi-mi:"MI:0465"(dip)	-	no-uniprot-update:	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/15	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rigid:5jhnWPY9q/plfb350HVBqacJhI8	false	sufficient binding region:26-196	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99PZ6	uniprotkb:P68036-1	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9|ensemblbacteria:AAL72314	intact:EBI-15556257|ensembl:ENSP00000344259	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:p68036-1(display_long)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16107297|imex:IM-23108-4|dip:DIP-197137E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:YP_009062537.1|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|ensemblbacteria:AAL72314(transcript)|ensemblbacteria:SF_p0227(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0016301"(kinase activity)|go:"GO:0043657"(host cell)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:4BVU	ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|intact:EBI-711173(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/15	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	rigid:n2bGHEoz8sWoDjd4z1DCNfmxgwg	false	sufficient binding region:26-196	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99PZ6	intact:EBI-4399559	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9|ensemblbacteria:AAL72314	dip:DIP-24261N	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:"MI:0071"(molecular sieving)	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16107297|imex:IM-23108-4|dip:DIP-197137E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:YP_009062537.1|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|ensemblbacteria:AAL72314(transcript)|ensemblbacteria:SF_p0227(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0016301"(kinase activity)|go:"GO:0043657"(host cell)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:4BVU	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	psi-mi:"MI:0465"(dip)	-	no-uniprot-update:	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/15	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rigid:n2bGHEoz8sWoDjd4z1DCNfmxgwg	false	sufficient binding region:26-196	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99PZ6	intact:EBI-4399559	intact:EBI-9316527|uniprotkb:Q7BCI9|uniprotkb:Q7BEJ9|ensemblbacteria:AAL72314	dip:DIP-24261N	psi-mi:ospg_shifl(display_long)|uniprotkb:ospG(gene name)|psi-mi:ospG(display_short)|uniprotkb:Effector protein OspG(gene name synonym)|uniprotkb:pWR501_0237(orf name)|uniprotkb:SFLP087(orf name)|uniprotkb:CP0227(locus name)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Grishin et al. (2014)	pubmed:24856362|doi:10.1016/j.str.2014.04.010|imex:IM-23108	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16107358|imex:IM-23108-7|dip:DIP-197138E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:YP_009062537.1|refseq:NP_085391.1|refseq:NP_858360.1|refseq:YP_006960315.1|dip:DIP-60998N|refseq:WP_000705601.1|ensemblbacteria:AAL72314(transcript)|ensemblbacteria:SF_p0227(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0016301"(kinase activity)|go:"GO:0043657"(host cell)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:4BVU	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	psi-mi:"MI:0465"(dip)	-	no-uniprot-update:	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/15	rogid:FPsLi8VnRiMTYRFqO3KjOS5SSOU623	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rigid:5jhnWPY9q/plfb350HVBqacJhI8	false	sufficient binding region:26-196	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)