#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P13382 uniprotkb:Q01454 intact:EBI-6128|uniprotkb:D6W177|ensemblfungi:YNL102W intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W psi-mi:dpoa_yeast(display_long)|uniprotkb:POL1(gene name)|psi-mi:POL1(display_short)|uniprotkb:CDC17(gene name synonym)|uniprotkb:"DNA polymerase alpha:primase complex p180 subunit"(gene name synonym)|uniprotkb:DNA polymerase I subunit A(gene name synonym)|uniprotkb:N2181(orf name)|uniprotkb:YNL102W(locus name) psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16105865|imex:IM-22686-1|dip:DIP-10406E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005046|refseq:NP_014297.3|dip:DIP-2526N|mint:P13382|ensemblfungi:YNL102W(gene)|ensemblfungi:YNL102W_mRNA(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|rcsb pdb:3FLO|rcsb pdb:3OIQ|rcsb pdb:4B08|rcsb pdb:4C93|rcsb pdb:4FVM|rcsb pdb:4FXD|rcsb pdb:4FYD|reactome:R-SCE-113501|reactome:R-SCE-68952|reactome:R-SCE-68962|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183 refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL psi-mi:"MI:0465"(dip) crc64:50C9032DBE95B5AE crc64:E2ABBB244B5F8B4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:bT1RBzE29FaKsuEOnt9APuT3awU559292 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rigid:T5bgC/yOGB2fi77lWHoiHO64dfY false sufficient binding region:1-351 sufficient binding region:471-927 - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q01454 uniprotkb:P13382 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-6128|uniprotkb:D6W177|ensemblfungi:YNL102W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:dpoa_yeast(display_long)|uniprotkb:POL1(gene name)|psi-mi:POL1(display_short)|uniprotkb:CDC17(gene name synonym)|uniprotkb:"DNA polymerase alpha:primase complex p180 subunit"(gene name synonym)|uniprotkb:DNA polymerase I subunit A(gene name synonym)|uniprotkb:N2181(orf name)|uniprotkb:YNL102W(locus name) psi-mi:"MI:0020"(transmission electron microscopy) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16105886|imex:IM-22686-2|dip:DIP-196533E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL sgd:S000005046|refseq:NP_014297.3|dip:DIP-2526N|mint:P13382|ensemblfungi:YNL102W(gene)|ensemblfungi:YNL102W_mRNA(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|rcsb pdb:3FLO|rcsb pdb:3OIQ|rcsb pdb:4B08|rcsb pdb:4C93|rcsb pdb:4FVM|rcsb pdb:4FXD|rcsb pdb:4FYD|reactome:R-SCE-113501|reactome:R-SCE-68952|reactome:R-SCE-68962|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:50C9032DBE95B5AE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:bT1RBzE29FaKsuEOnt9APuT3awU559292 rigid:EtpraPZ3FJ5Hwcfjt7EAT5QPC58 false sufficient binding region:471-927 sufficient binding region:1-351 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01454 uniprotkb:Q12488 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-22066|uniprotkb:D6VRZ9|ensemblfungi:YDR013W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:psf1_yeast(display_long)|uniprotkb:Partner of Sld five 1(gene name synonym)|uniprotkb:YDR013W(locus name)|uniprotkb:YD8119.18(orf name)|uniprotkb:PZA208(orf name)|uniprotkb:PSF1(gene name)|psi-mi:PSF1(display_short) psi-mi:"MI:0020"(transmission electron microscopy) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16105886|imex:IM-22686-2|dip:DIP-196533E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL sgd:S000002420|refseq:NP_010296.3|dip:DIP-1812N|go:"GO:0071162"(CMG complex)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974|ensemblfungi:YDR013W(gene)|ensemblfungi:YDR013W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|mint:Q12488 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:4667D8152C1AB5B4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:gFGPyjIrRFLZEYnz/ugV//hl2zs559292 rigid:EtpraPZ3FJ5Hwcfjt7EAT5QPC58 false sufficient binding region:471-927 sufficient binding region:1-164 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01454 uniprotkb:P40359 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-25936|uniprotkb:D6VWB1|ensemblfungi:YJL072C psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:psf2_yeast(display_long)|uniprotkb:PSF2(gene name)|psi-mi:PSF2(display_short)|uniprotkb:YJL072C(locus name)|uniprotkb:J1086(orf name)|uniprotkb:Partner of Sld five 2(gene name synonym)|uniprotkb:HRF213(orf name) psi-mi:"MI:0020"(transmission electron microscopy) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16105886|imex:IM-22686-2|dip:DIP-196533E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL refseq:NP_012463.1|sgd:S000003608|mint:P40359|dip:DIP-3858N|ensemblfungi:YJL072C(gene)|ensemblfungi:YJL072C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:C8B52C0462A37A3A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:BI1dFftT0v1WZ6AQRUDkTi+mdgA559292 rigid:EtpraPZ3FJ5Hwcfjt7EAT5QPC58 false sufficient binding region:471-927 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01454 uniprotkb:Q12146 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-30392|uniprotkb:D6W1S3|ensemblfungi:YOL146W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:psf3_yeast(display_long)|uniprotkb:YOL146W(locus name)|uniprotkb:Partner of Sld five 3(gene name synonym)|uniprotkb:PSF3(gene name)|psi-mi:PSF3(display_short) psi-mi:"MI:0020"(transmission electron microscopy) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16105886|imex:IM-22686-2|dip:DIP-196533E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL refseq:NP_014495.2|sgd:S000005506|dip:DIP-4461N|mint:Q12146|ensemblfungi:YOL146W(gene)|ensemblfungi:YOL146W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:3E8B60DFCE16391D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:wPLgebaZqVSf/ym9bOxp++xENeA559292 rigid:EtpraPZ3FJ5Hwcfjt7EAT5QPC58 false sufficient binding region:471-927 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01454 uniprotkb:Q03406 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-37437|uniprotkb:Q6Q558|uniprotkb:D6VTB2|ensemblfungi:YDR489W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:sld5_yeast(display_long)|uniprotkb:YDR489W(locus name)|uniprotkb:SLD5(gene name)|psi-mi:SLD5(display_short) psi-mi:"MI:0020"(transmission electron microscopy) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16105886|imex:IM-22686-2|dip:DIP-196533E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL sgd:S000002897|refseq:NP_010777.3|mint:Q03406|dip:DIP-1813N|ensemblfungi:YDR489W(gene)|ensemblfungi:YDR489W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:4C95|rcsb pdb:5NXQ|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:7EC516ADAD9900DD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:O9Vu+11KYnU+PPCFaiCepQFayPM559292 rigid:EtpraPZ3FJ5Hwcfjt7EAT5QPC58 false sufficient binding region:471-927 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01454 uniprotkb:Q01454 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16105913|imex:IM-22686-3|dip:DIP-196530E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:E2ABBB244B5F8B4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rigid:t+GPp9SpARpgeeL34JRt1V3mLNk false sufficient binding region:471-927 sufficient binding region:471-927 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03406 uniprotkb:Q01454 intact:EBI-37437|uniprotkb:Q6Q558|uniprotkb:D6VTB2|ensemblfungi:YDR489W intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W psi-mi:sld5_yeast(display_long)|uniprotkb:YDR489W(locus name)|uniprotkb:SLD5(gene name)|psi-mi:SLD5(display_short) psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:"MI:0096"(pull down) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16105931|imex:IM-22686-4|dip:DIP-196532E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002897|refseq:NP_010777.3|mint:Q03406|dip:DIP-1813N|ensemblfungi:YDR489W(gene)|ensemblfungi:YDR489W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:4C95|rcsb pdb:5NXQ|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL psi-mi:"MI:0465"(dip) crc64:7EC516ADAD9900DD crc64:E2ABBB244B5F8B4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:O9Vu+11KYnU+PPCFaiCepQFayPM559292 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rigid:qYSTo7so6YGlQVGSPivGVrwZpl8 false sufficient binding region:1-18|mutation disrupting interaction strength:8-8|mutation disrupting interaction strength:9-9|glutathione s tranferase tag:n-n sufficient binding region:471-927 - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q01454 uniprotkb:Q01454 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:"MI:0067"(light scattering) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16105960|imex:IM-22686-5|dip:DIP-196530E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:E2ABBB244B5F8B4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rigid:t+GPp9SpARpgeeL34JRt1V3mLNk false sufficient binding region:471-927 sufficient binding region:471-927 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01454 uniprotkb:Q01454 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16105978|imex:IM-22686-6|dip:DIP-196530E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:E2ABBB244B5F8B4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rigid:t+GPp9SpARpgeeL34JRt1V3mLNk false sufficient binding region:471-927 sufficient binding region:471-927 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12488 uniprotkb:P40359 intact:EBI-22066|uniprotkb:D6VRZ9|ensemblfungi:YDR013W intact:EBI-25936|uniprotkb:D6VWB1|ensemblfungi:YJL072C psi-mi:psf1_yeast(display_long)|uniprotkb:Partner of Sld five 1(gene name synonym)|uniprotkb:YDR013W(locus name)|uniprotkb:YD8119.18(orf name)|uniprotkb:PZA208(orf name)|uniprotkb:PSF1(gene name)|psi-mi:PSF1(display_short) psi-mi:psf2_yeast(display_long)|uniprotkb:PSF2(gene name)|psi-mi:PSF2(display_short)|uniprotkb:YJL072C(locus name)|uniprotkb:J1086(orf name)|uniprotkb:Partner of Sld five 2(gene name synonym)|uniprotkb:HRF213(orf name) psi-mi:"MI:0029"(cosedimentation through density gradient) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16105996|imex:IM-22686-7|dip:DIP-109566E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002420|refseq:NP_010296.3|dip:DIP-1812N|go:"GO:0071162"(CMG complex)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974|ensemblfungi:YDR013W(gene)|ensemblfungi:YDR013W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|mint:Q12488 refseq:NP_012463.1|sgd:S000003608|mint:P40359|dip:DIP-3858N|ensemblfungi:YJL072C(gene)|ensemblfungi:YJL072C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:4667D8152C1AB5B4 crc64:C8B52C0462A37A3A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:gFGPyjIrRFLZEYnz/ugV//hl2zs559292 rogid:BI1dFftT0v1WZ6AQRUDkTi+mdgA559292 rigid:Napq3/XUQ8IX5yS5LX06kWzm3kk false sufficient binding region:1-164 - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q12488 uniprotkb:Q12146 intact:EBI-22066|uniprotkb:D6VRZ9|ensemblfungi:YDR013W intact:EBI-30392|uniprotkb:D6W1S3|ensemblfungi:YOL146W psi-mi:psf1_yeast(display_long)|uniprotkb:Partner of Sld five 1(gene name synonym)|uniprotkb:YDR013W(locus name)|uniprotkb:YD8119.18(orf name)|uniprotkb:PZA208(orf name)|uniprotkb:PSF1(gene name)|psi-mi:PSF1(display_short) psi-mi:psf3_yeast(display_long)|uniprotkb:YOL146W(locus name)|uniprotkb:Partner of Sld five 3(gene name synonym)|uniprotkb:PSF3(gene name)|psi-mi:PSF3(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16105996|imex:IM-22686-7|dip:DIP-109566E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002420|refseq:NP_010296.3|dip:DIP-1812N|go:"GO:0071162"(CMG complex)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974|ensemblfungi:YDR013W(gene)|ensemblfungi:YDR013W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|mint:Q12488 refseq:NP_014495.2|sgd:S000005506|dip:DIP-4461N|mint:Q12146|ensemblfungi:YOL146W(gene)|ensemblfungi:YOL146W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:4667D8152C1AB5B4 crc64:3E8B60DFCE16391D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:gFGPyjIrRFLZEYnz/ugV//hl2zs559292 rogid:wPLgebaZqVSf/ym9bOxp++xENeA559292 rigid:Napq3/XUQ8IX5yS5LX06kWzm3kk false sufficient binding region:1-164 - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q12488 uniprotkb:Q03406 intact:EBI-22066|uniprotkb:D6VRZ9|ensemblfungi:YDR013W intact:EBI-37437|uniprotkb:Q6Q558|uniprotkb:D6VTB2|ensemblfungi:YDR489W psi-mi:psf1_yeast(display_long)|uniprotkb:Partner of Sld five 1(gene name synonym)|uniprotkb:YDR013W(locus name)|uniprotkb:YD8119.18(orf name)|uniprotkb:PZA208(orf name)|uniprotkb:PSF1(gene name)|psi-mi:PSF1(display_short) psi-mi:sld5_yeast(display_long)|uniprotkb:YDR489W(locus name)|uniprotkb:SLD5(gene name)|psi-mi:SLD5(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16105996|imex:IM-22686-7|dip:DIP-109566E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002420|refseq:NP_010296.3|dip:DIP-1812N|go:"GO:0071162"(CMG complex)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974|ensemblfungi:YDR013W(gene)|ensemblfungi:YDR013W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|mint:Q12488 sgd:S000002897|refseq:NP_010777.3|mint:Q03406|dip:DIP-1813N|ensemblfungi:YDR489W(gene)|ensemblfungi:YDR489W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:4C95|rcsb pdb:5NXQ|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:4667D8152C1AB5B4 crc64:7EC516ADAD9900DD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:gFGPyjIrRFLZEYnz/ugV//hl2zs559292 rogid:O9Vu+11KYnU+PPCFaiCepQFayPM559292 rigid:Napq3/XUQ8IX5yS5LX06kWzm3kk false sufficient binding region:1-164 - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q01454 uniprotkb:Q01454 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16106017|imex:IM-22686-8|dip:DIP-196530E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:E2ABBB244B5F8B4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rigid:t+GPp9SpARpgeeL34JRt1V3mLNk false sufficient binding region:471-927 sufficient binding region:471-927 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30665 uniprotkb:P29469 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106056|imex:IM-22686-10|dip:DIP-196535E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N psi-mi:"MI:0465"(dip) crc64:382D542AE38975E3 crc64:F38FF682581B0EC0 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 rigid:l6XTy7ySEnwErOUfNPhHdFU7vvE false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30665 uniprotkb:P53091 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-10556|uniprotkb:Q870M9|ensemblfungi:YGL201C|uniprotkb:D6VTV3 psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:mcm6_yeast(display_long)|uniprotkb:YGL201C(locus name)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:Minichromosome maintenance protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106056|imex:IM-22686-10|dip:DIP-196535E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 ensemblfungi:YGL201C(gene)|refseq:NP_011314.2|sgd:S000003169|ensemblfungi:YGL201C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:5V8F|mint:P53091|dip:DIP-1294N psi-mi:"MI:0465"(dip) crc64:382D542AE38975E3 crc64:03AB793134E64A50 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:b2Pak0d6eENHIzSFaBge/kPQceU559292 rigid:l6XTy7ySEnwErOUfNPhHdFU7vvE false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30665 uniprotkb:P29496 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-10549|ensemblfungi:YLR274W|uniprotkb:D6VYS1 psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:mcm5_yeast(display_long)|uniprotkb:MCM5(gene name)|psi-mi:MCM5(display_short)|uniprotkb:CDC46(gene name synonym)|uniprotkb:YLR274W(locus name)|uniprotkb:L9328.1(orf name)|uniprotkb:Cell division control protein 46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106056|imex:IM-22686-10|dip:DIP-196535E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 refseq:NP_013376.1|sgd:S000004264|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:3JC5|rcsb pdb:6WGG|rcsb pdb:6WGI|ensemblfungi:YLR274W(gene)|ensemblfungi:YLR274W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|reactome:R-SCE-68949|reactome:R-SCE-69052|reactome:R-SCE-68962|dip:DIP-2406N psi-mi:"MI:0465"(dip) crc64:382D542AE38975E3 crc64:01D9DE208A091CF2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:a8UgYOklJ5vWqhA0hbQTCWNQg0Y559292 rigid:l6XTy7ySEnwErOUfNPhHdFU7vvE false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P13382 uniprotkb:Q01454 intact:EBI-6128|uniprotkb:D6W177|ensemblfungi:YNL102W intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W psi-mi:dpoa_yeast(display_long)|uniprotkb:POL1(gene name)|psi-mi:POL1(display_short)|uniprotkb:CDC17(gene name synonym)|uniprotkb:"DNA polymerase alpha:primase complex p180 subunit"(gene name synonym)|uniprotkb:DNA polymerase I subunit A(gene name synonym)|uniprotkb:N2181(orf name)|uniprotkb:YNL102W(locus name) psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16106035|imex:IM-22686-9|dip:DIP-10406E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005046|refseq:NP_014297.3|dip:DIP-2526N|mint:P13382|ensemblfungi:YNL102W(gene)|ensemblfungi:YNL102W_mRNA(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|rcsb pdb:3FLO|rcsb pdb:3OIQ|rcsb pdb:4B08|rcsb pdb:4C93|rcsb pdb:4FVM|rcsb pdb:4FXD|rcsb pdb:4FYD|reactome:R-SCE-113501|reactome:R-SCE-68952|reactome:R-SCE-68962|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183 refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL psi-mi:"MI:0465"(dip) crc64:50C9032DBE95B5AE crc64:E2ABBB244B5F8B4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:bT1RBzE29FaKsuEOnt9APuT3awU559292 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rigid:T5bgC/yOGB2fi77lWHoiHO64dfY false sufficient binding region:1-351 sufficient binding region:471-927 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01454 uniprotkb:Q01454 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16106079|imex:IM-22686-11|dip:DIP-196530E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:E2ABBB244B5F8B4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rigid:t+GPp9SpARpgeeL34JRt1V3mLNk false sufficient binding region:471-927 sufficient binding region:471-927 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01454 uniprotkb:Q12488 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-22066|uniprotkb:D6VRZ9|ensemblfungi:YDR013W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:psf1_yeast(display_long)|uniprotkb:Partner of Sld five 1(gene name synonym)|uniprotkb:YDR013W(locus name)|uniprotkb:YD8119.18(orf name)|uniprotkb:PZA208(orf name)|uniprotkb:PSF1(gene name)|psi-mi:PSF1(display_short) psi-mi:"MI:0071"(molecular sieving) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106118|imex:IM-22686-13|dip:DIP-150136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL sgd:S000002420|refseq:NP_010296.3|dip:DIP-1812N|go:"GO:0071162"(CMG complex)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974|ensemblfungi:YDR013W(gene)|ensemblfungi:YDR013W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|mint:Q12488 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:4667D8152C1AB5B4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:gFGPyjIrRFLZEYnz/ugV//hl2zs559292 rigid:endjP27pYQ++HhpXLEyVxSCVU+w false sufficient binding region:471-927 sufficient binding region:1-164 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01454 uniprotkb:P40359 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-25936|uniprotkb:D6VWB1|ensemblfungi:YJL072C psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:psf2_yeast(display_long)|uniprotkb:PSF2(gene name)|psi-mi:PSF2(display_short)|uniprotkb:YJL072C(locus name)|uniprotkb:J1086(orf name)|uniprotkb:Partner of Sld five 2(gene name synonym)|uniprotkb:HRF213(orf name) psi-mi:"MI:0071"(molecular sieving) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106118|imex:IM-22686-13|dip:DIP-150136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL refseq:NP_012463.1|sgd:S000003608|mint:P40359|dip:DIP-3858N|ensemblfungi:YJL072C(gene)|ensemblfungi:YJL072C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:C8B52C0462A37A3A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:BI1dFftT0v1WZ6AQRUDkTi+mdgA559292 rigid:endjP27pYQ++HhpXLEyVxSCVU+w false sufficient binding region:471-927 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01454 uniprotkb:Q12146 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-30392|uniprotkb:D6W1S3|ensemblfungi:YOL146W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:psf3_yeast(display_long)|uniprotkb:YOL146W(locus name)|uniprotkb:Partner of Sld five 3(gene name synonym)|uniprotkb:PSF3(gene name)|psi-mi:PSF3(display_short) psi-mi:"MI:0071"(molecular sieving) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106118|imex:IM-22686-13|dip:DIP-150136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL refseq:NP_014495.2|sgd:S000005506|dip:DIP-4461N|mint:Q12146|ensemblfungi:YOL146W(gene)|ensemblfungi:YOL146W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:3E8B60DFCE16391D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:wPLgebaZqVSf/ym9bOxp++xENeA559292 rigid:endjP27pYQ++HhpXLEyVxSCVU+w false sufficient binding region:471-927 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01454 uniprotkb:Q03406 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-37437|uniprotkb:Q6Q558|uniprotkb:D6VTB2|ensemblfungi:YDR489W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:sld5_yeast(display_long)|uniprotkb:YDR489W(locus name)|uniprotkb:SLD5(gene name)|psi-mi:SLD5(display_short) psi-mi:"MI:0071"(molecular sieving) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106118|imex:IM-22686-13|dip:DIP-150136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL sgd:S000002897|refseq:NP_010777.3|mint:Q03406|dip:DIP-1813N|ensemblfungi:YDR489W(gene)|ensemblfungi:YDR489W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:4C95|rcsb pdb:5NXQ|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:7EC516ADAD9900DD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:O9Vu+11KYnU+PPCFaiCepQFayPM559292 rigid:endjP27pYQ++HhpXLEyVxSCVU+w false sufficient binding region:471-927 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12488 uniprotkb:P40359 intact:EBI-22066|uniprotkb:D6VRZ9|ensemblfungi:YDR013W intact:EBI-25936|uniprotkb:D6VWB1|ensemblfungi:YJL072C psi-mi:psf1_yeast(display_long)|uniprotkb:Partner of Sld five 1(gene name synonym)|uniprotkb:YDR013W(locus name)|uniprotkb:YD8119.18(orf name)|uniprotkb:PZA208(orf name)|uniprotkb:PSF1(gene name)|psi-mi:PSF1(display_short) psi-mi:psf2_yeast(display_long)|uniprotkb:PSF2(gene name)|psi-mi:PSF2(display_short)|uniprotkb:YJL072C(locus name)|uniprotkb:J1086(orf name)|uniprotkb:Partner of Sld five 2(gene name synonym)|uniprotkb:HRF213(orf name) psi-mi:"MI:0071"(molecular sieving) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106097|imex:IM-22686-12|dip:DIP-109566E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002420|refseq:NP_010296.3|dip:DIP-1812N|go:"GO:0071162"(CMG complex)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974|ensemblfungi:YDR013W(gene)|ensemblfungi:YDR013W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|mint:Q12488 refseq:NP_012463.1|sgd:S000003608|mint:P40359|dip:DIP-3858N|ensemblfungi:YJL072C(gene)|ensemblfungi:YJL072C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:4667D8152C1AB5B4 crc64:C8B52C0462A37A3A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:gFGPyjIrRFLZEYnz/ugV//hl2zs559292 rogid:BI1dFftT0v1WZ6AQRUDkTi+mdgA559292 rigid:Napq3/XUQ8IX5yS5LX06kWzm3kk false sufficient binding region:1-164 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12488 uniprotkb:Q12146 intact:EBI-22066|uniprotkb:D6VRZ9|ensemblfungi:YDR013W intact:EBI-30392|uniprotkb:D6W1S3|ensemblfungi:YOL146W psi-mi:psf1_yeast(display_long)|uniprotkb:Partner of Sld five 1(gene name synonym)|uniprotkb:YDR013W(locus name)|uniprotkb:YD8119.18(orf name)|uniprotkb:PZA208(orf name)|uniprotkb:PSF1(gene name)|psi-mi:PSF1(display_short) psi-mi:psf3_yeast(display_long)|uniprotkb:YOL146W(locus name)|uniprotkb:Partner of Sld five 3(gene name synonym)|uniprotkb:PSF3(gene name)|psi-mi:PSF3(display_short) psi-mi:"MI:0071"(molecular sieving) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106097|imex:IM-22686-12|dip:DIP-109566E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002420|refseq:NP_010296.3|dip:DIP-1812N|go:"GO:0071162"(CMG complex)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974|ensemblfungi:YDR013W(gene)|ensemblfungi:YDR013W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|mint:Q12488 refseq:NP_014495.2|sgd:S000005506|dip:DIP-4461N|mint:Q12146|ensemblfungi:YOL146W(gene)|ensemblfungi:YOL146W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:4667D8152C1AB5B4 crc64:3E8B60DFCE16391D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:gFGPyjIrRFLZEYnz/ugV//hl2zs559292 rogid:wPLgebaZqVSf/ym9bOxp++xENeA559292 rigid:Napq3/XUQ8IX5yS5LX06kWzm3kk false sufficient binding region:1-164 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12488 uniprotkb:Q03406 intact:EBI-22066|uniprotkb:D6VRZ9|ensemblfungi:YDR013W intact:EBI-37437|uniprotkb:Q6Q558|uniprotkb:D6VTB2|ensemblfungi:YDR489W psi-mi:psf1_yeast(display_long)|uniprotkb:Partner of Sld five 1(gene name synonym)|uniprotkb:YDR013W(locus name)|uniprotkb:YD8119.18(orf name)|uniprotkb:PZA208(orf name)|uniprotkb:PSF1(gene name)|psi-mi:PSF1(display_short) psi-mi:sld5_yeast(display_long)|uniprotkb:YDR489W(locus name)|uniprotkb:SLD5(gene name)|psi-mi:SLD5(display_short) psi-mi:"MI:0071"(molecular sieving) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106097|imex:IM-22686-12|dip:DIP-109566E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002420|refseq:NP_010296.3|dip:DIP-1812N|go:"GO:0071162"(CMG complex)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974|ensemblfungi:YDR013W(gene)|ensemblfungi:YDR013W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|mint:Q12488 sgd:S000002897|refseq:NP_010777.3|mint:Q03406|dip:DIP-1813N|ensemblfungi:YDR489W(gene)|ensemblfungi:YDR489W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:4C95|rcsb pdb:5NXQ|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:4667D8152C1AB5B4 crc64:7EC516ADAD9900DD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/08 2017/08/10 rogid:gFGPyjIrRFLZEYnz/ugV//hl2zs559292 rogid:O9Vu+11KYnU+PPCFaiCepQFayPM559292 rigid:Napq3/XUQ8IX5yS5LX06kWzm3kk false sufficient binding region:1-164 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01454 uniprotkb:P13382 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-6128|uniprotkb:D6W177|ensemblfungi:YNL102W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:dpoa_yeast(display_long)|uniprotkb:POL1(gene name)|psi-mi:POL1(display_short)|uniprotkb:CDC17(gene name synonym)|uniprotkb:"DNA polymerase alpha:primase complex p180 subunit"(gene name synonym)|uniprotkb:DNA polymerase I subunit A(gene name synonym)|uniprotkb:N2181(orf name)|uniprotkb:YNL102W(locus name) psi-mi:"MI:0029"(cosedimentation through density gradient) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106142|imex:IM-22686-14|dip:DIP-196533E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL sgd:S000005046|refseq:NP_014297.3|dip:DIP-2526N|mint:P13382|ensemblfungi:YNL102W(gene)|ensemblfungi:YNL102W_mRNA(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|rcsb pdb:3FLO|rcsb pdb:3OIQ|rcsb pdb:4B08|rcsb pdb:4C93|rcsb pdb:4FVM|rcsb pdb:4FXD|rcsb pdb:4FYD|reactome:R-SCE-113501|reactome:R-SCE-68952|reactome:R-SCE-68962|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:50C9032DBE95B5AE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:bT1RBzE29FaKsuEOnt9APuT3awU559292 rigid:EtpraPZ3FJ5Hwcfjt7EAT5QPC58 false sufficient binding region:471-927 sufficient binding region:1-351 - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q01454 uniprotkb:Q12488 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-22066|uniprotkb:D6VRZ9|ensemblfungi:YDR013W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:psf1_yeast(display_long)|uniprotkb:Partner of Sld five 1(gene name synonym)|uniprotkb:YDR013W(locus name)|uniprotkb:YD8119.18(orf name)|uniprotkb:PZA208(orf name)|uniprotkb:PSF1(gene name)|psi-mi:PSF1(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106142|imex:IM-22686-14|dip:DIP-196533E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL sgd:S000002420|refseq:NP_010296.3|dip:DIP-1812N|go:"GO:0071162"(CMG complex)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974|ensemblfungi:YDR013W(gene)|ensemblfungi:YDR013W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|mint:Q12488 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:4667D8152C1AB5B4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:gFGPyjIrRFLZEYnz/ugV//hl2zs559292 rigid:EtpraPZ3FJ5Hwcfjt7EAT5QPC58 false sufficient binding region:471-927 sufficient binding region:1-164 - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q01454 uniprotkb:P40359 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-25936|uniprotkb:D6VWB1|ensemblfungi:YJL072C psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:psf2_yeast(display_long)|uniprotkb:PSF2(gene name)|psi-mi:PSF2(display_short)|uniprotkb:YJL072C(locus name)|uniprotkb:J1086(orf name)|uniprotkb:Partner of Sld five 2(gene name synonym)|uniprotkb:HRF213(orf name) psi-mi:"MI:0029"(cosedimentation through density gradient) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106142|imex:IM-22686-14|dip:DIP-196533E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL refseq:NP_012463.1|sgd:S000003608|mint:P40359|dip:DIP-3858N|ensemblfungi:YJL072C(gene)|ensemblfungi:YJL072C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:C8B52C0462A37A3A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:BI1dFftT0v1WZ6AQRUDkTi+mdgA559292 rigid:EtpraPZ3FJ5Hwcfjt7EAT5QPC58 false sufficient binding region:471-927 - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q01454 uniprotkb:Q12146 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-30392|uniprotkb:D6W1S3|ensemblfungi:YOL146W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:psf3_yeast(display_long)|uniprotkb:YOL146W(locus name)|uniprotkb:Partner of Sld five 3(gene name synonym)|uniprotkb:PSF3(gene name)|psi-mi:PSF3(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106142|imex:IM-22686-14|dip:DIP-196533E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL refseq:NP_014495.2|sgd:S000005506|dip:DIP-4461N|mint:Q12146|ensemblfungi:YOL146W(gene)|ensemblfungi:YOL146W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:3E8B60DFCE16391D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:wPLgebaZqVSf/ym9bOxp++xENeA559292 rigid:EtpraPZ3FJ5Hwcfjt7EAT5QPC58 false sufficient binding region:471-927 - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q01454 uniprotkb:Q03406 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-37437|uniprotkb:Q6Q558|uniprotkb:D6VTB2|ensemblfungi:YDR489W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:sld5_yeast(display_long)|uniprotkb:YDR489W(locus name)|uniprotkb:SLD5(gene name)|psi-mi:SLD5(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106142|imex:IM-22686-14|dip:DIP-196533E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL sgd:S000002897|refseq:NP_010777.3|mint:Q03406|dip:DIP-1813N|ensemblfungi:YDR489W(gene)|ensemblfungi:YDR489W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:4C95|rcsb pdb:5NXQ|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:7EC516ADAD9900DD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:O9Vu+11KYnU+PPCFaiCepQFayPM559292 rigid:EtpraPZ3FJ5Hwcfjt7EAT5QPC58 false sufficient binding region:471-927 - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P13382 uniprotkb:Q01454 intact:EBI-6128|uniprotkb:D6W177|ensemblfungi:YNL102W intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W psi-mi:dpoa_yeast(display_long)|uniprotkb:POL1(gene name)|psi-mi:POL1(display_short)|uniprotkb:CDC17(gene name synonym)|uniprotkb:"DNA polymerase alpha:primase complex p180 subunit"(gene name synonym)|uniprotkb:DNA polymerase I subunit A(gene name synonym)|uniprotkb:N2181(orf name)|uniprotkb:YNL102W(locus name) psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:"MI:0096"(pull down) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16106169|imex:IM-22686-15|dip:DIP-10406E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005046|refseq:NP_014297.3|dip:DIP-2526N|mint:P13382|ensemblfungi:YNL102W(gene)|ensemblfungi:YNL102W_mRNA(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|rcsb pdb:3FLO|rcsb pdb:3OIQ|rcsb pdb:4B08|rcsb pdb:4C93|rcsb pdb:4FVM|rcsb pdb:4FXD|rcsb pdb:4FYD|reactome:R-SCE-113501|reactome:R-SCE-68952|reactome:R-SCE-68962|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183 refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL psi-mi:"MI:0465"(dip) crc64:50C9032DBE95B5AE crc64:E2ABBB244B5F8B4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:bT1RBzE29FaKsuEOnt9APuT3awU559292 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rigid:T5bgC/yOGB2fi77lWHoiHO64dfY false sufficient binding region:137-149|mutation disrupting interaction strength:140-140|mutation disrupting interaction strength:142-142|mutation disrupting interaction strength:143-143|mutation disrupting interaction strength:144-144|mutation disrupting interaction strength:147-147|glutathione s tranferase tag:n-n sufficient binding region:471-927 - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q03406 uniprotkb:Q01454 intact:EBI-37437|uniprotkb:Q6Q558|uniprotkb:D6VTB2|ensemblfungi:YDR489W intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W psi-mi:sld5_yeast(display_long)|uniprotkb:YDR489W(locus name)|uniprotkb:SLD5(gene name)|psi-mi:SLD5(display_short) psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:"MI:0017"(classical fluorescence spectroscopy) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16106207|imex:IM-22686-16|dip:DIP-196532E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002897|refseq:NP_010777.3|mint:Q03406|dip:DIP-1813N|ensemblfungi:YDR489W(gene)|ensemblfungi:YDR489W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:4C95|rcsb pdb:5NXQ|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL psi-mi:"MI:0465"(dip) crc64:7EC516ADAD9900DD crc64:E2ABBB244B5F8B4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:O9Vu+11KYnU+PPCFaiCepQFayPM559292 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rigid:qYSTo7so6YGlQVGSPivGVrwZpl8 false sufficient binding region:1-19|fluorescein label:n-n sufficient binding region:471-927 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13382 uniprotkb:Q01454 intact:EBI-6128|uniprotkb:D6W177|ensemblfungi:YNL102W intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W psi-mi:dpoa_yeast(display_long)|uniprotkb:POL1(gene name)|psi-mi:POL1(display_short)|uniprotkb:CDC17(gene name synonym)|uniprotkb:"DNA polymerase alpha:primase complex p180 subunit"(gene name synonym)|uniprotkb:DNA polymerase I subunit A(gene name synonym)|uniprotkb:N2181(orf name)|uniprotkb:YNL102W(locus name) psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:"MI:0017"(classical fluorescence spectroscopy) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16106230|imex:IM-22686-17|dip:DIP-10406E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005046|refseq:NP_014297.3|dip:DIP-2526N|mint:P13382|ensemblfungi:YNL102W(gene)|ensemblfungi:YNL102W_mRNA(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|rcsb pdb:3FLO|rcsb pdb:3OIQ|rcsb pdb:4B08|rcsb pdb:4C93|rcsb pdb:4FVM|rcsb pdb:4FXD|rcsb pdb:4FYD|reactome:R-SCE-113501|reactome:R-SCE-68952|reactome:R-SCE-68962|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183 refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL psi-mi:"MI:0465"(dip) crc64:50C9032DBE95B5AE crc64:E2ABBB244B5F8B4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:bT1RBzE29FaKsuEOnt9APuT3awU559292 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rigid:T5bgC/yOGB2fi77lWHoiHO64dfY false sufficient binding region:137-149|fluorescein label:n-n sufficient binding region:471-927 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30665 uniprotkb:Q12146 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-30392|uniprotkb:D6W1S3|ensemblfungi:YOL146W psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:psf3_yeast(display_long)|uniprotkb:YOL146W(locus name)|uniprotkb:Partner of Sld five 3(gene name synonym)|uniprotkb:PSF3(gene name)|psi-mi:PSF3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106253|imex:IM-22686-18|dip:DIP-196534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 refseq:NP_014495.2|sgd:S000005506|dip:DIP-4461N|mint:Q12146|ensemblfungi:YOL146W(gene)|ensemblfungi:YOL146W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:382D542AE38975E3 crc64:3E8B60DFCE16391D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:wPLgebaZqVSf/ym9bOxp++xENeA559292 rigid:99GbAMtTcyO509ECagZFggL7Mas false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30665 uniprotkb:Q08032 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-4292|uniprotkb:Q05908|uniprotkb:D6VYA3|ensemblfungi:YLR103C psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:cdc45_yeast(display_long)|uniprotkb:CDC45(gene name)|psi-mi:CDC45(display_short)|uniprotkb:YLR103C(locus name)|uniprotkb:L8004.11(orf name)|uniprotkb:SLD4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106253|imex:IM-22686-18|dip:DIP-196534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 refseq:NP_013204.1|sgd:S000004093|dip:DIP-2405N|mint:Q08032|ensemblfungi:YLR103C(gene)|ensemblfungi:YLR103C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-68962 psi-mi:"MI:0465"(dip) crc64:382D542AE38975E3 crc64:6500DDD62EC4E8EE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:ErMEWxRKsJsPBDo5EfTfBL57hAY559292 rigid:99GbAMtTcyO509ECagZFggL7Mas false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30665 uniprotkb:Q12488 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-22066|uniprotkb:D6VRZ9|ensemblfungi:YDR013W psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:psf1_yeast(display_long)|uniprotkb:Partner of Sld five 1(gene name synonym)|uniprotkb:YDR013W(locus name)|uniprotkb:YD8119.18(orf name)|uniprotkb:PZA208(orf name)|uniprotkb:PSF1(gene name)|psi-mi:PSF1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106253|imex:IM-22686-18|dip:DIP-196534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 sgd:S000002420|refseq:NP_010296.3|dip:DIP-1812N|go:"GO:0071162"(CMG complex)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974|ensemblfungi:YDR013W(gene)|ensemblfungi:YDR013W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|mint:Q12488 psi-mi:"MI:0465"(dip) crc64:382D542AE38975E3 crc64:4667D8152C1AB5B4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:gFGPyjIrRFLZEYnz/ugV//hl2zs559292 rigid:99GbAMtTcyO509ECagZFggL7Mas false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30665 uniprotkb:Q03406 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-37437|uniprotkb:Q6Q558|uniprotkb:D6VTB2|ensemblfungi:YDR489W psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:sld5_yeast(display_long)|uniprotkb:YDR489W(locus name)|uniprotkb:SLD5(gene name)|psi-mi:SLD5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106253|imex:IM-22686-18|dip:DIP-196534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 sgd:S000002897|refseq:NP_010777.3|mint:Q03406|dip:DIP-1813N|ensemblfungi:YDR489W(gene)|ensemblfungi:YDR489W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:4C95|rcsb pdb:5NXQ|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:382D542AE38975E3 crc64:7EC516ADAD9900DD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:O9Vu+11KYnU+PPCFaiCepQFayPM559292 rigid:99GbAMtTcyO509ECagZFggL7Mas false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30665 uniprotkb:P13382 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-6128|uniprotkb:D6W177|ensemblfungi:YNL102W psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:dpoa_yeast(display_long)|uniprotkb:POL1(gene name)|psi-mi:POL1(display_short)|uniprotkb:CDC17(gene name synonym)|uniprotkb:"DNA polymerase alpha:primase complex p180 subunit"(gene name synonym)|uniprotkb:DNA polymerase I subunit A(gene name synonym)|uniprotkb:N2181(orf name)|uniprotkb:YNL102W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106253|imex:IM-22686-18|dip:DIP-196534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 sgd:S000005046|refseq:NP_014297.3|dip:DIP-2526N|mint:P13382|ensemblfungi:YNL102W(gene)|ensemblfungi:YNL102W_mRNA(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|rcsb pdb:3FLO|rcsb pdb:3OIQ|rcsb pdb:4B08|rcsb pdb:4C93|rcsb pdb:4FVM|rcsb pdb:4FXD|rcsb pdb:4FYD|reactome:R-SCE-113501|reactome:R-SCE-68952|reactome:R-SCE-68962|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183 psi-mi:"MI:0465"(dip) crc64:382D542AE38975E3 crc64:50C9032DBE95B5AE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:bT1RBzE29FaKsuEOnt9APuT3awU559292 rigid:99GbAMtTcyO509ECagZFggL7Mas false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30665 uniprotkb:Q01454 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106253|imex:IM-22686-18|dip:DIP-196534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL psi-mi:"MI:0465"(dip) crc64:382D542AE38975E3 crc64:E2ABBB244B5F8B4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rigid:99GbAMtTcyO509ECagZFggL7Mas false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30665 uniprotkb:Q04659 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-28093|uniprotkb:D6VZM3|ensemblfungi:YMR048W psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:csm3_yeast(display_long)|uniprotkb:CSM3(gene name)|psi-mi:CSM3(display_short)|uniprotkb:YM9796.01(orf name)|uniprotkb:YMR048W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106253|imex:IM-22686-18|dip:DIP-196534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 refseq:NP_013763.1|sgd:S000004651|dip:DIP-1944N|mint:Q04659|rcsb pdb:6SKL|ensemblfungi:YMR048W(gene)|ensemblfungi:YMR048W_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0043111"(replication fork arrest)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0048478"(replication fork protection)|interpro:IPR012923(Replication fork protection component Swi3)|interpro:IPR040038 psi-mi:"MI:0465"(dip) crc64:382D542AE38975E3 crc64:0B92F561F91197AE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:FByICfMNh2I1hF8jrR45/ZlgqhQ559292 rigid:99GbAMtTcyO509ECagZFggL7Mas false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30665 uniprotkb:Q04636 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-27863|uniprotkb:D6VZA4|ensemblfungi:YML069W psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:pob3_yeast(display_long)|uniprotkb:YML069W(locus name)|uniprotkb:Facilitates chromatin transcription complex subunit POB3(gene name synonym)|uniprotkb:POB3(gene name)|psi-mi:POB3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106253|imex:IM-22686-18|dip:DIP-196534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 refseq:NP_013642.1|sgd:S000004534|dip:DIP-4083N|mint:Q04636|ensemblfungi:YML069W(gene)|ensemblfungi:YML069W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR038167|rcsb pdb:2GCJ|rcsb pdb:2GCL|rcsb pdb:3F5R|rcsb pdb:4PQ0|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6804756|reactome:R-SCE-75955|go:"GO:0031298"(replication fork protection complex) psi-mi:"MI:0465"(dip) crc64:382D542AE38975E3 crc64:02C04F620C7B1450 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:P1VkOQ4LPSsxfSZaDykpvS9FRPU559292 rigid:99GbAMtTcyO509ECagZFggL7Mas false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30665 uniprotkb:P29469 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106253|imex:IM-22686-18|dip:DIP-196534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N psi-mi:"MI:0465"(dip) crc64:382D542AE38975E3 crc64:F38FF682581B0EC0 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 rigid:99GbAMtTcyO509ECagZFggL7Mas false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30665 uniprotkb:P53091 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-10556|uniprotkb:Q870M9|ensemblfungi:YGL201C|uniprotkb:D6VTV3 psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:mcm6_yeast(display_long)|uniprotkb:YGL201C(locus name)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:Minichromosome maintenance protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106253|imex:IM-22686-18|dip:DIP-196534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 ensemblfungi:YGL201C(gene)|refseq:NP_011314.2|sgd:S000003169|ensemblfungi:YGL201C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:5V8F|mint:P53091|dip:DIP-1294N psi-mi:"MI:0465"(dip) crc64:382D542AE38975E3 crc64:03AB793134E64A50 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:b2Pak0d6eENHIzSFaBge/kPQceU559292 rigid:99GbAMtTcyO509ECagZFggL7Mas false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30665 uniprotkb:P29496 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W intact:EBI-10549|ensemblfungi:YLR274W|uniprotkb:D6VYS1 psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:mcm5_yeast(display_long)|uniprotkb:MCM5(gene name)|psi-mi:MCM5(display_short)|uniprotkb:CDC46(gene name synonym)|uniprotkb:YLR274W(locus name)|uniprotkb:L9328.1(orf name)|uniprotkb:Cell division control protein 46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106253|imex:IM-22686-18|dip:DIP-196534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 refseq:NP_013376.1|sgd:S000004264|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:3JC5|rcsb pdb:6WGG|rcsb pdb:6WGI|ensemblfungi:YLR274W(gene)|ensemblfungi:YLR274W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|reactome:R-SCE-68949|reactome:R-SCE-69052|reactome:R-SCE-68962|dip:DIP-2406N psi-mi:"MI:0465"(dip) crc64:382D542AE38975E3 crc64:01D9DE208A091CF2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rogid:a8UgYOklJ5vWqhA0hbQTCWNQg0Y559292 rigid:99GbAMtTcyO509ECagZFggL7Mas false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P13382 uniprotkb:Q01454 intact:EBI-6128|uniprotkb:D6W177|ensemblfungi:YNL102W intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W psi-mi:dpoa_yeast(display_long)|uniprotkb:POL1(gene name)|psi-mi:POL1(display_short)|uniprotkb:CDC17(gene name synonym)|uniprotkb:"DNA polymerase alpha:primase complex p180 subunit"(gene name synonym)|uniprotkb:DNA polymerase I subunit A(gene name synonym)|uniprotkb:N2181(orf name)|uniprotkb:YNL102W(locus name) psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106282|imex:IM-22686-19|dip:DIP-196531E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005046|refseq:NP_014297.3|dip:DIP-2526N|mint:P13382|ensemblfungi:YNL102W(gene)|ensemblfungi:YNL102W_mRNA(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|rcsb pdb:3FLO|rcsb pdb:3OIQ|rcsb pdb:4B08|rcsb pdb:4C93|rcsb pdb:4FVM|rcsb pdb:4FXD|rcsb pdb:4FYD|reactome:R-SCE-113501|reactome:R-SCE-68952|reactome:R-SCE-68962|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183 refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL psi-mi:"MI:0465"(dip) crc64:50C9032DBE95B5AE crc64:E2ABBB244B5F8B4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:bT1RBzE29FaKsuEOnt9APuT3awU559292 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rigid:ZtGCUR4W3lCcujjTk2F7jRAz3j8 false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P13382 uniprotkb:P24279 intact:EBI-6128|uniprotkb:D6W177|ensemblfungi:YNL102W intact:EBI-10541|ensemblfungi:YEL032W|uniprotkb:D3DLL7 psi-mi:dpoa_yeast(display_long)|uniprotkb:POL1(gene name)|psi-mi:POL1(display_short)|uniprotkb:CDC17(gene name synonym)|uniprotkb:"DNA polymerase alpha:primase complex p180 subunit"(gene name synonym)|uniprotkb:DNA polymerase I subunit A(gene name synonym)|uniprotkb:N2181(orf name)|uniprotkb:YNL102W(locus name) psi-mi:mcm3_yeast(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:YEL032W(locus name)|uniprotkb:SYGP-ORF23(orf name)|uniprotkb:Minichromosome maintenance protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106282|imex:IM-22686-19|dip:DIP-196531E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005046|refseq:NP_014297.3|dip:DIP-2526N|mint:P13382|ensemblfungi:YNL102W(gene)|ensemblfungi:YNL102W_mRNA(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|rcsb pdb:3FLO|rcsb pdb:3OIQ|rcsb pdb:4B08|rcsb pdb:4C93|rcsb pdb:4FVM|rcsb pdb:4FXD|rcsb pdb:4FYD|reactome:R-SCE-113501|reactome:R-SCE-68952|reactome:R-SCE-68962|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183 refseq:NP_010882.1|sgd:S000000758|go:"GO:0005524"(ATP binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1904931"(MCM complex binding)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGC|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:5XF8|ensemblfungi:YEL032W(gene)|ensemblfungi:YEL032W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|mint:P24279|dip:DIP-2407N psi-mi:"MI:0465"(dip) crc64:50C9032DBE95B5AE crc64:43DD4DACAF4456DC full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:bT1RBzE29FaKsuEOnt9APuT3awU559292 rogid:OsFbdaTeE1vPQObriGt5M6mTPzk559292 rigid:ZtGCUR4W3lCcujjTk2F7jRAz3j8 false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P13382 uniprotkb:Q08032 intact:EBI-6128|uniprotkb:D6W177|ensemblfungi:YNL102W intact:EBI-4292|uniprotkb:Q05908|uniprotkb:D6VYA3|ensemblfungi:YLR103C psi-mi:dpoa_yeast(display_long)|uniprotkb:POL1(gene name)|psi-mi:POL1(display_short)|uniprotkb:CDC17(gene name synonym)|uniprotkb:"DNA polymerase alpha:primase complex p180 subunit"(gene name synonym)|uniprotkb:DNA polymerase I subunit A(gene name synonym)|uniprotkb:N2181(orf name)|uniprotkb:YNL102W(locus name) psi-mi:cdc45_yeast(display_long)|uniprotkb:CDC45(gene name)|psi-mi:CDC45(display_short)|uniprotkb:YLR103C(locus name)|uniprotkb:L8004.11(orf name)|uniprotkb:SLD4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106282|imex:IM-22686-19|dip:DIP-196531E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005046|refseq:NP_014297.3|dip:DIP-2526N|mint:P13382|ensemblfungi:YNL102W(gene)|ensemblfungi:YNL102W_mRNA(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|rcsb pdb:3FLO|rcsb pdb:3OIQ|rcsb pdb:4B08|rcsb pdb:4C93|rcsb pdb:4FVM|rcsb pdb:4FXD|rcsb pdb:4FYD|reactome:R-SCE-113501|reactome:R-SCE-68952|reactome:R-SCE-68962|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183 refseq:NP_013204.1|sgd:S000004093|dip:DIP-2405N|mint:Q08032|ensemblfungi:YLR103C(gene)|ensemblfungi:YLR103C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-68962 psi-mi:"MI:0465"(dip) crc64:50C9032DBE95B5AE crc64:6500DDD62EC4E8EE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:bT1RBzE29FaKsuEOnt9APuT3awU559292 rogid:ErMEWxRKsJsPBDo5EfTfBL57hAY559292 rigid:ZtGCUR4W3lCcujjTk2F7jRAz3j8 false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P13382 uniprotkb:Q12488 intact:EBI-6128|uniprotkb:D6W177|ensemblfungi:YNL102W intact:EBI-22066|uniprotkb:D6VRZ9|ensemblfungi:YDR013W psi-mi:dpoa_yeast(display_long)|uniprotkb:POL1(gene name)|psi-mi:POL1(display_short)|uniprotkb:CDC17(gene name synonym)|uniprotkb:"DNA polymerase alpha:primase complex p180 subunit"(gene name synonym)|uniprotkb:DNA polymerase I subunit A(gene name synonym)|uniprotkb:N2181(orf name)|uniprotkb:YNL102W(locus name) psi-mi:psf1_yeast(display_long)|uniprotkb:Partner of Sld five 1(gene name synonym)|uniprotkb:YDR013W(locus name)|uniprotkb:YD8119.18(orf name)|uniprotkb:PZA208(orf name)|uniprotkb:PSF1(gene name)|psi-mi:PSF1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106282|imex:IM-22686-19|dip:DIP-196531E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005046|refseq:NP_014297.3|dip:DIP-2526N|mint:P13382|ensemblfungi:YNL102W(gene)|ensemblfungi:YNL102W_mRNA(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|rcsb pdb:3FLO|rcsb pdb:3OIQ|rcsb pdb:4B08|rcsb pdb:4C93|rcsb pdb:4FVM|rcsb pdb:4FXD|rcsb pdb:4FYD|reactome:R-SCE-113501|reactome:R-SCE-68952|reactome:R-SCE-68962|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183 sgd:S000002420|refseq:NP_010296.3|dip:DIP-1812N|go:"GO:0071162"(CMG complex)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974|ensemblfungi:YDR013W(gene)|ensemblfungi:YDR013W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|mint:Q12488 psi-mi:"MI:0465"(dip) crc64:50C9032DBE95B5AE crc64:4667D8152C1AB5B4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:bT1RBzE29FaKsuEOnt9APuT3awU559292 rogid:gFGPyjIrRFLZEYnz/ugV//hl2zs559292 rigid:ZtGCUR4W3lCcujjTk2F7jRAz3j8 false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P13382 uniprotkb:Q03406 intact:EBI-6128|uniprotkb:D6W177|ensemblfungi:YNL102W intact:EBI-37437|uniprotkb:Q6Q558|uniprotkb:D6VTB2|ensemblfungi:YDR489W psi-mi:dpoa_yeast(display_long)|uniprotkb:POL1(gene name)|psi-mi:POL1(display_short)|uniprotkb:CDC17(gene name synonym)|uniprotkb:"DNA polymerase alpha:primase complex p180 subunit"(gene name synonym)|uniprotkb:DNA polymerase I subunit A(gene name synonym)|uniprotkb:N2181(orf name)|uniprotkb:YNL102W(locus name) psi-mi:sld5_yeast(display_long)|uniprotkb:YDR489W(locus name)|uniprotkb:SLD5(gene name)|psi-mi:SLD5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16106282|imex:IM-22686-19|dip:DIP-196531E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005046|refseq:NP_014297.3|dip:DIP-2526N|mint:P13382|ensemblfungi:YNL102W(gene)|ensemblfungi:YNL102W_mRNA(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|rcsb pdb:3FLO|rcsb pdb:3OIQ|rcsb pdb:4B08|rcsb pdb:4C93|rcsb pdb:4FVM|rcsb pdb:4FXD|rcsb pdb:4FYD|reactome:R-SCE-113501|reactome:R-SCE-68952|reactome:R-SCE-68962|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183 sgd:S000002897|refseq:NP_010777.3|mint:Q03406|dip:DIP-1813N|ensemblfungi:YDR489W(gene)|ensemblfungi:YDR489W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:4C95|rcsb pdb:5NXQ|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:50C9032DBE95B5AE crc64:7EC516ADAD9900DD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:bT1RBzE29FaKsuEOnt9APuT3awU559292 rogid:O9Vu+11KYnU+PPCFaiCepQFayPM559292 rigid:ZtGCUR4W3lCcujjTk2F7jRAz3j8 false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P13382 uniprotkb:Q01454 intact:EBI-6128|uniprotkb:D6W177|ensemblfungi:YNL102W intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W psi-mi:dpoa_yeast(display_long)|uniprotkb:POL1(gene name)|psi-mi:POL1(display_short)|uniprotkb:CDC17(gene name synonym)|uniprotkb:"DNA polymerase alpha:primase complex p180 subunit"(gene name synonym)|uniprotkb:DNA polymerase I subunit A(gene name synonym)|uniprotkb:N2181(orf name)|uniprotkb:YNL102W(locus name) psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16106327|imex:IM-22686-21|dip:DIP-10406E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005046|refseq:NP_014297.3|dip:DIP-2526N|mint:P13382|ensemblfungi:YNL102W(gene)|ensemblfungi:YNL102W_mRNA(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|rcsb pdb:3FLO|rcsb pdb:3OIQ|rcsb pdb:4B08|rcsb pdb:4C93|rcsb pdb:4FVM|rcsb pdb:4FXD|rcsb pdb:4FYD|reactome:R-SCE-113501|reactome:R-SCE-68952|reactome:R-SCE-68962|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183 refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL psi-mi:"MI:0465"(dip) crc64:50C9032DBE95B5AE crc64:E2ABBB244B5F8B4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:bT1RBzE29FaKsuEOnt9APuT3awU559292 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rigid:T5bgC/yOGB2fi77lWHoiHO64dfY false sufficient binding region:137-149 sufficient binding region:471-927 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13382 uniprotkb:Q01454 intact:EBI-6128|uniprotkb:D6W177|ensemblfungi:YNL102W intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W psi-mi:dpoa_yeast(display_long)|uniprotkb:POL1(gene name)|psi-mi:POL1(display_short)|uniprotkb:CDC17(gene name synonym)|uniprotkb:"DNA polymerase alpha:primase complex p180 subunit"(gene name synonym)|uniprotkb:DNA polymerase I subunit A(gene name synonym)|uniprotkb:N2181(orf name)|uniprotkb:YNL102W(locus name) psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16106305|imex:IM-22686-20|dip:DIP-10406E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005046|refseq:NP_014297.3|dip:DIP-2526N|mint:P13382|ensemblfungi:YNL102W(gene)|ensemblfungi:YNL102W_mRNA(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|rcsb pdb:3FLO|rcsb pdb:3OIQ|rcsb pdb:4B08|rcsb pdb:4C93|rcsb pdb:4FVM|rcsb pdb:4FXD|rcsb pdb:4FYD|reactome:R-SCE-113501|reactome:R-SCE-68952|reactome:R-SCE-68962|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183 refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL psi-mi:"MI:0465"(dip) crc64:50C9032DBE95B5AE crc64:E2ABBB244B5F8B4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:bT1RBzE29FaKsuEOnt9APuT3awU559292 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rigid:T5bgC/yOGB2fi77lWHoiHO64dfY false sufficient binding region:137-149 sufficient binding region:471-927 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03406 uniprotkb:Q01454 intact:EBI-37437|uniprotkb:Q6Q558|uniprotkb:D6VTB2|ensemblfungi:YDR489W intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W psi-mi:sld5_yeast(display_long)|uniprotkb:YDR489W(locus name)|uniprotkb:SLD5(gene name)|psi-mi:SLD5(display_short) psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16106348|imex:IM-22686-22|dip:DIP-196532E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002897|refseq:NP_010777.3|mint:Q03406|dip:DIP-1813N|ensemblfungi:YDR489W(gene)|ensemblfungi:YDR489W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:4C95|rcsb pdb:5NXQ|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL psi-mi:"MI:0465"(dip) crc64:7EC516ADAD9900DD crc64:E2ABBB244B5F8B4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:O9Vu+11KYnU+PPCFaiCepQFayPM559292 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rigid:qYSTo7so6YGlQVGSPivGVrwZpl8 false sufficient binding region:1-19 sufficient binding region:471-927 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01454 uniprotkb:Q12488 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-22066|uniprotkb:D6VRZ9|ensemblfungi:YDR013W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:psf1_yeast(display_long)|uniprotkb:Partner of Sld five 1(gene name synonym)|uniprotkb:YDR013W(locus name)|uniprotkb:YD8119.18(orf name)|uniprotkb:PZA208(orf name)|uniprotkb:PSF1(gene name)|psi-mi:PSF1(display_short) psi-mi:"MI:0020"(transmission electron microscopy) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106391|imex:IM-22686-24|dip:DIP-150136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL sgd:S000002420|refseq:NP_010296.3|dip:DIP-1812N|go:"GO:0071162"(CMG complex)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974|ensemblfungi:YDR013W(gene)|ensemblfungi:YDR013W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|mint:Q12488 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:4667D8152C1AB5B4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:gFGPyjIrRFLZEYnz/ugV//hl2zs559292 rigid:endjP27pYQ++HhpXLEyVxSCVU+w false sufficient binding region:471-927 sufficient binding region:1-164 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01454 uniprotkb:P40359 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-25936|uniprotkb:D6VWB1|ensemblfungi:YJL072C psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:psf2_yeast(display_long)|uniprotkb:PSF2(gene name)|psi-mi:PSF2(display_short)|uniprotkb:YJL072C(locus name)|uniprotkb:J1086(orf name)|uniprotkb:Partner of Sld five 2(gene name synonym)|uniprotkb:HRF213(orf name) psi-mi:"MI:0020"(transmission electron microscopy) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106391|imex:IM-22686-24|dip:DIP-150136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL refseq:NP_012463.1|sgd:S000003608|mint:P40359|dip:DIP-3858N|ensemblfungi:YJL072C(gene)|ensemblfungi:YJL072C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:C8B52C0462A37A3A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:BI1dFftT0v1WZ6AQRUDkTi+mdgA559292 rigid:endjP27pYQ++HhpXLEyVxSCVU+w false sufficient binding region:471-927 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01454 uniprotkb:Q12146 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-30392|uniprotkb:D6W1S3|ensemblfungi:YOL146W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:psf3_yeast(display_long)|uniprotkb:YOL146W(locus name)|uniprotkb:Partner of Sld five 3(gene name synonym)|uniprotkb:PSF3(gene name)|psi-mi:PSF3(display_short) psi-mi:"MI:0020"(transmission electron microscopy) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106391|imex:IM-22686-24|dip:DIP-150136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL refseq:NP_014495.2|sgd:S000005506|dip:DIP-4461N|mint:Q12146|ensemblfungi:YOL146W(gene)|ensemblfungi:YOL146W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:3E8B60DFCE16391D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:wPLgebaZqVSf/ym9bOxp++xENeA559292 rigid:endjP27pYQ++HhpXLEyVxSCVU+w false sufficient binding region:471-927 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01454 uniprotkb:Q03406 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-37437|uniprotkb:Q6Q558|uniprotkb:D6VTB2|ensemblfungi:YDR489W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:sld5_yeast(display_long)|uniprotkb:YDR489W(locus name)|uniprotkb:SLD5(gene name)|psi-mi:SLD5(display_short) psi-mi:"MI:0020"(transmission electron microscopy) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106391|imex:IM-22686-24|dip:DIP-150136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL sgd:S000002897|refseq:NP_010777.3|mint:Q03406|dip:DIP-1813N|ensemblfungi:YDR489W(gene)|ensemblfungi:YDR489W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:4C95|rcsb pdb:5NXQ|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:7EC516ADAD9900DD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:O9Vu+11KYnU+PPCFaiCepQFayPM559292 rigid:endjP27pYQ++HhpXLEyVxSCVU+w false sufficient binding region:471-927 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03406 uniprotkb:Q01454 intact:EBI-37437|uniprotkb:Q6Q558|uniprotkb:D6VTB2|ensemblfungi:YDR489W intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W psi-mi:sld5_yeast(display_long)|uniprotkb:YDR489W(locus name)|uniprotkb:SLD5(gene name)|psi-mi:SLD5(display_short) psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16106370|imex:IM-22686-23|dip:DIP-196532E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002897|refseq:NP_010777.3|mint:Q03406|dip:DIP-1813N|ensemblfungi:YDR489W(gene)|ensemblfungi:YDR489W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:4C95|rcsb pdb:5NXQ|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL psi-mi:"MI:0465"(dip) crc64:7EC516ADAD9900DD crc64:E2ABBB244B5F8B4D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:O9Vu+11KYnU+PPCFaiCepQFayPM559292 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rigid:qYSTo7so6YGlQVGSPivGVrwZpl8 false sufficient binding region:1-19 sufficient binding region:471-927 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01454 uniprotkb:Q12488 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-22066|uniprotkb:D6VRZ9|ensemblfungi:YDR013W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:psf1_yeast(display_long)|uniprotkb:Partner of Sld five 1(gene name synonym)|uniprotkb:YDR013W(locus name)|uniprotkb:YD8119.18(orf name)|uniprotkb:PZA208(orf name)|uniprotkb:PSF1(gene name)|psi-mi:PSF1(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106415|imex:IM-22686-25|dip:DIP-150136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL sgd:S000002420|refseq:NP_010296.3|dip:DIP-1812N|go:"GO:0071162"(CMG complex)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974|ensemblfungi:YDR013W(gene)|ensemblfungi:YDR013W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|mint:Q12488 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:4667D8152C1AB5B4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:gFGPyjIrRFLZEYnz/ugV//hl2zs559292 rigid:endjP27pYQ++HhpXLEyVxSCVU+w false sufficient binding region:471-927 sufficient binding region:1-164 - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q01454 uniprotkb:P40359 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-25936|uniprotkb:D6VWB1|ensemblfungi:YJL072C psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:psf2_yeast(display_long)|uniprotkb:PSF2(gene name)|psi-mi:PSF2(display_short)|uniprotkb:YJL072C(locus name)|uniprotkb:J1086(orf name)|uniprotkb:Partner of Sld five 2(gene name synonym)|uniprotkb:HRF213(orf name) psi-mi:"MI:0029"(cosedimentation through density gradient) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106415|imex:IM-22686-25|dip:DIP-150136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL refseq:NP_012463.1|sgd:S000003608|mint:P40359|dip:DIP-3858N|ensemblfungi:YJL072C(gene)|ensemblfungi:YJL072C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:C8B52C0462A37A3A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:BI1dFftT0v1WZ6AQRUDkTi+mdgA559292 rigid:endjP27pYQ++HhpXLEyVxSCVU+w false sufficient binding region:471-927 - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q01454 uniprotkb:Q12146 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-30392|uniprotkb:D6W1S3|ensemblfungi:YOL146W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:psf3_yeast(display_long)|uniprotkb:YOL146W(locus name)|uniprotkb:Partner of Sld five 3(gene name synonym)|uniprotkb:PSF3(gene name)|psi-mi:PSF3(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106415|imex:IM-22686-25|dip:DIP-150136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL refseq:NP_014495.2|sgd:S000005506|dip:DIP-4461N|mint:Q12146|ensemblfungi:YOL146W(gene)|ensemblfungi:YOL146W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:3E8B60DFCE16391D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:wPLgebaZqVSf/ym9bOxp++xENeA559292 rigid:endjP27pYQ++HhpXLEyVxSCVU+w false sufficient binding region:471-927 - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q01454 uniprotkb:Q03406 intact:EBI-5209|uniprotkb:D6W4D2|ensemblfungi:YPR135W intact:EBI-37437|uniprotkb:Q6Q558|uniprotkb:D6VTB2|ensemblfungi:YDR489W psi-mi:ctf4_yeast(display_long)|uniprotkb:CTF4(gene name)|psi-mi:CTF4(display_short)|uniprotkb:CHL15(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:YPR135W(locus name)|uniprotkb:P9659.7(orf name)|uniprotkb:Chromosome transmission fidelity protein 4(gene name synonym)|uniprotkb:Protein POB1(gene name synonym)|uniprotkb:Chromosome replication protein CHL15(gene name synonym) psi-mi:sld5_yeast(display_long)|uniprotkb:YDR489W(locus name)|uniprotkb:SLD5(gene name)|psi-mi:SLD5(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Simon et al. (2014) pubmed:24805245|doi:10.1038/nature13234|imex:IM-22686 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16106415|imex:IM-22686-25|dip:DIP-150136E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015461.1|sgd:S000006339|dip:DIP-4640N|mint:Q01454|ensemblfungi:YPR135W(gene)|ensemblfungi:YPR135W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034085"(establishment of sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022100|interpro:IPR036322|rcsb pdb:4C8H|rcsb pdb:4C8S|rcsb pdb:4C93|rcsb pdb:4C95|rcsb pdb:5HOG|rcsb pdb:5HOI|rcsb pdb:5NXQ|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL sgd:S000002897|refseq:NP_010777.3|mint:Q03406|dip:DIP-1813N|ensemblfungi:YDR489W(gene)|ensemblfungi:YDR489W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:4C95|rcsb pdb:5NXQ|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974 psi-mi:"MI:0465"(dip) crc64:E2ABBB244B5F8B4D crc64:7EC516ADAD9900DD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:GpPHDi7V8oAR1Yv+o5xAZLuG8AE559292 rogid:O9Vu+11KYnU+PPCFaiCepQFayPM559292 rigid:endjP27pYQ++HhpXLEyVxSCVU+w false sufficient binding region:471-927 - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining)