#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:C5DEB9	uniprotkb:C5DF24	intact:EBI-6558887|ensemblfungi:CAR22130	intact:EBI-6558893|ensemblfungi:CAR22779	psi-mi:c5deb9_lactc(display_long)|uniprotkb:KLTH0C07942g(locus name)	psi-mi:c5df24_lactc(display_long)|uniprotkb:KLTH0D11660g(locus name)	psi-mi:"MI:0071"(molecular sieving)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:559295(lactc)|taxid:559295("Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)")	taxid:559295(lactc)|taxid:559295("Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104949|imex:IM-22702-1|dip:DIP-196565E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:CAR22130(transcript)|ensemblfungi:KLTH0C07942g(gene)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0006914"(autophagy)|interpro:IPR018621|rcsb pdb:4HPQ|rcsb pdb:4P1W|rcsb pdb:5JHF|refseq:XP_002552568.1|dip:DIP-60846N	ensemblfungi:CAR22779(transcript)|ensemblfungi:KLTH0D11660g(gene)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0015031"(protein transport)|interpro:IPR039113|interpro:IPR039362|interpro:IPR040666|rcsb pdb:4HPQ|rcsb pdb:4P1W|rcsb pdb:5JHF|refseq:XP_002553217.1|dip:DIP-60847N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:jIaKEbr59vcj7dtkME3Rdr9Er64559295	rogid:o9DlnsaFIbWVsQRGlbJOXwJ6eCk559295	rigid:hyHYu6AXJBdM8I9lLWkRWIBbpcc	false	sufficient binding region:1-86	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:C5DEB9	uniprotkb:C5DFJ6	intact:EBI-6558887|ensemblfungi:CAR22130	intact:EBI-6558880|ensemblfungi:CAR22951	psi-mi:c5deb9_lactc(display_long)|uniprotkb:KLTH0C07942g(locus name)	psi-mi:c5dfj6_lactc(display_long)|uniprotkb:KLTH0D15642g(locus name)	psi-mi:"MI:0071"(molecular sieving)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:559295(lactc)|taxid:559295("Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)")	taxid:559295(lactc)|taxid:559295("Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104949|imex:IM-22702-1|dip:DIP-196565E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:CAR22130(transcript)|ensemblfungi:KLTH0C07942g(gene)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0006914"(autophagy)|interpro:IPR018621|rcsb pdb:4HPQ|rcsb pdb:4P1W|rcsb pdb:5JHF|refseq:XP_002552568.1|dip:DIP-60846N	ensemblfungi:CAR22951(transcript)|ensemblfungi:KLTH0D15642g(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|interpro:IPR007240(Autophagy protein 17)|rcsb pdb:4HPQ|rcsb pdb:4P1W|rcsb pdb:5JHF|refseq:XP_002553389.1|dip:DIP-60845N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:jIaKEbr59vcj7dtkME3Rdr9Er64559295	rogid:QBDi57c3zpd7P52vitMh9KxNqbg559295	rigid:hyHYu6AXJBdM8I9lLWkRWIBbpcc	false	sufficient binding region:1-86	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:W0TA43	uniprotkb:W0T9X4	intact:EBI-16104996|ensemblfungi:BAO40497	intact:EBI-16104970|ensemblfungi:BAO39616	psi-mi:atg13_klumd(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:KLMA_40473(orf name)	psi-mi:atg1_klumd(display_long)|uniprotkb:Autophagy-related protein 1(gene name synonym)|uniprotkb:KLMA_30321(orf name)|uniprotkb:ATG1(gene name)|psi-mi:ATG1(display_short)	psi-mi:"MI:0071"(molecular sieving)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:1003335(kluyveromyces marxianus dmku3-1042)|taxid:1003335(Kluyveromyces marxianus DMKU3-1042)	taxid:1003335(kluyveromyces marxianus dmku3-1042)|taxid:1003335(Kluyveromyces marxianus DMKU3-1042)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105014|imex:IM-22702-2|dip:DIP-196562E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:BAO40497(transcript)|ensemblfungi:KLMA_40473(gene)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|rcsb pdb:4P1N|dip:DIP-60844N	ensemblfungi:BAO39616(transcript)|ensemblfungi:KLMA_30321(gene)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0061709"(reticulophagy)|go:"GO:0061908"(phagophore)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|rcsb pdb:4P1N|go:"GO:0000422"(autophagy of mitochondrion)|dip:DIP-60843N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:gvPAKr5uf/OxApRRfu7pfRtAIj81003335	rogid:DAaYY0sJKcy/l2Oe7FBEfxDnjNI1003335	rigid:ulfV5JvcoQL6WHKZxFxFyGN1Mj8	false	sufficient binding region:441-500	sufficient binding region:566-836	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06410	uniprotkb:Q06628	intact:EBI-30856|uniprotkb:D6VZ59|ensemblfungi:YLR423C	intact:EBI-36188|uniprotkb:D6W4I5|ensemblfungi:YPR185W	psi-mi:atg17_yeast(display_long)|uniprotkb:ATG17(gene name)|psi-mi:ATG17(display_short)|uniprotkb:APG17(gene name synonym)|uniprotkb:YLR423C(locus name)	psi-mi:atg13_yeast(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:APG13(gene name synonym)|uniprotkb:YPR185W(locus name)	psi-mi:"MI:0096"(pull down)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105085|imex:IM-22702-5|dip:DIP-185611E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004415|refseq:NP_013527.3|dip:DIP-1490N|mint:Q06410|ensemblfungi:YLR423C(gene)|ensemblfungi:YLR423C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0045772"(positive regulation of autophagosome size)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR007240(Autophagy protein 17)	refseq:NP_015511.1|sgd:S000006389|mint:Q06628|dip:DIP-1191N|ensemblfungi:YPR185W(gene)|ensemblfungi:YPR185W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|rcsb pdb:6KBM|rcsb pdb:6KBN|reactome:R-SCE-1632852|go:"GO:0019887"(protein kinase regulator activity)	psi-mi:"MI:0465"(dip)	crc64:71504B6C76549B75	crc64:45CD16F69B795E62	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:cOX1btuNKiBhY8roD022C0NYxG4559292	rogid:Op8+j2qoEeML+DW19641V5t7/js559292	rigid:c/fMrShM4ZDmz/USayRwEOczN+0	false	mutation disrupting interaction strength:250-250,247-247|mutation disrupting interaction strength:247-247|mutation decreasing interaction strength:243-243,240-240|mutation decreasing interaction strength:216-216,213-213	glutathione s tranferase tag:n-n|sufficient binding region:424-436	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:W0TA43	uniprotkb:W0T9X4	intact:EBI-16104996|ensemblfungi:BAO40497	intact:EBI-16104970|ensemblfungi:BAO39616	psi-mi:atg13_klumd(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:KLMA_40473(orf name)	psi-mi:atg1_klumd(display_long)|uniprotkb:Autophagy-related protein 1(gene name synonym)|uniprotkb:KLMA_30321(orf name)|uniprotkb:ATG1(gene name)|psi-mi:ATG1(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:1003335(kluyveromyces marxianus dmku3-1042)|taxid:1003335(Kluyveromyces marxianus DMKU3-1042)	taxid:1003335(kluyveromyces marxianus dmku3-1042)|taxid:1003335(Kluyveromyces marxianus DMKU3-1042)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105122|imex:IM-22702-6|dip:DIP-196562E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:BAO40497(transcript)|ensemblfungi:KLMA_40473(gene)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|rcsb pdb:4P1N|dip:DIP-60844N	ensemblfungi:BAO39616(transcript)|ensemblfungi:KLMA_30321(gene)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0061709"(reticulophagy)|go:"GO:0061908"(phagophore)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|rcsb pdb:4P1N|go:"GO:0000422"(autophagy of mitochondrion)|dip:DIP-60843N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:gvPAKr5uf/OxApRRfu7pfRtAIj81003335	rogid:DAaYY0sJKcy/l2Oe7FBEfxDnjNI1003335	rigid:ulfV5JvcoQL6WHKZxFxFyGN1Mj8	false	sufficient binding region:441-500	sufficient binding region:566-836	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06628	uniprotkb:P53104	intact:EBI-36188|uniprotkb:D6W4I5|ensemblfungi:YPR185W	intact:EBI-2657|uniprotkb:D6VTX3|ensemblfungi:YGL180W	psi-mi:atg13_yeast(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:APG13(gene name synonym)|uniprotkb:YPR185W(locus name)	psi-mi:atg1_yeast(display_long)|uniprotkb:ATG1(gene name)|psi-mi:ATG1(display_short)|uniprotkb:APG1(gene name synonym)|uniprotkb:AUT3(gene name synonym)|uniprotkb:YGL180W(locus name)|uniprotkb:G1615(orf name)|uniprotkb:CVT10(gene name synonym)|uniprotkb:Autophagy-related protein 1(gene name synonym)|uniprotkb:Autophagy protein 3(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105064|imex:IM-22702-4|dip:DIP-1389E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015511.1|sgd:S000006389|mint:Q06628|dip:DIP-1191N|ensemblfungi:YPR185W(gene)|ensemblfungi:YPR185W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|rcsb pdb:6KBM|rcsb pdb:6KBN|reactome:R-SCE-1632852|go:"GO:0019887"(protein kinase regulator activity)	refseq:NP_011335.1|sgd:S000003148|dip:DIP-1192N|mint:P53104|ensemblfungi:YGL180W(gene)|ensemblfungi:YGL180W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0044805"(late nucleophagy)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0061709"(reticulophagy)|go:"GO:0061908"(phagophore)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|reactome:R-SCE-1632852|reactome:R-SCE-8934903	psi-mi:"MI:0465"(dip)	crc64:45CD16F69B795E62	crc64:7F4C785AA3A7CC46	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:Op8+j2qoEeML+DW19641V5t7/js559292	rogid:b5bLJuCqm9VArsQteYG2dqv+KwA559292	rigid:mQxIJFjX5kHy8rSWW1nxyG4yYLU	false	ha tag:c-c	green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06628	uniprotkb:P53104	intact:EBI-36188|uniprotkb:D6W4I5|ensemblfungi:YPR185W	intact:EBI-2657|uniprotkb:D6VTX3|ensemblfungi:YGL180W	psi-mi:atg13_yeast(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:APG13(gene name synonym)|uniprotkb:YPR185W(locus name)	psi-mi:atg1_yeast(display_long)|uniprotkb:ATG1(gene name)|psi-mi:ATG1(display_short)|uniprotkb:APG1(gene name synonym)|uniprotkb:AUT3(gene name synonym)|uniprotkb:YGL180W(locus name)|uniprotkb:G1615(orf name)|uniprotkb:CVT10(gene name synonym)|uniprotkb:Autophagy-related protein 1(gene name synonym)|uniprotkb:Autophagy protein 3(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105035|imex:IM-22702-3|dip:DIP-1389E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015511.1|sgd:S000006389|mint:Q06628|dip:DIP-1191N|ensemblfungi:YPR185W(gene)|ensemblfungi:YPR185W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|rcsb pdb:6KBM|rcsb pdb:6KBN|reactome:R-SCE-1632852|go:"GO:0019887"(protein kinase regulator activity)	refseq:NP_011335.1|sgd:S000003148|dip:DIP-1192N|mint:P53104|ensemblfungi:YGL180W(gene)|ensemblfungi:YGL180W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0044805"(late nucleophagy)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0061709"(reticulophagy)|go:"GO:0061908"(phagophore)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|reactome:R-SCE-1632852|reactome:R-SCE-8934903	psi-mi:"MI:0465"(dip)	crc64:45CD16F69B795E62	crc64:7F4C785AA3A7CC46	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:Op8+j2qoEeML+DW19641V5t7/js559292	rogid:b5bLJuCqm9VArsQteYG2dqv+KwA559292	rigid:mQxIJFjX5kHy8rSWW1nxyG4yYLU	false	sufficient binding region:460-491|mutation disrupting interaction strength:472-472,468-468|glutathione s tranferase tag:c-c|necessary binding region:460-521	sufficient binding region:587-897	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q06410	uniprotkb:Q06628	intact:EBI-30856|uniprotkb:D6VZ59|ensemblfungi:YLR423C	intact:EBI-36188|uniprotkb:D6W4I5|ensemblfungi:YPR185W	psi-mi:atg17_yeast(display_long)|uniprotkb:ATG17(gene name)|psi-mi:ATG17(display_short)|uniprotkb:APG17(gene name synonym)|uniprotkb:YLR423C(locus name)	psi-mi:atg13_yeast(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:APG13(gene name synonym)|uniprotkb:YPR185W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105143|imex:IM-22702-7|dip:DIP-185611E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004415|refseq:NP_013527.3|dip:DIP-1490N|mint:Q06410|ensemblfungi:YLR423C(gene)|ensemblfungi:YLR423C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0045772"(positive regulation of autophagosome size)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR007240(Autophagy protein 17)	refseq:NP_015511.1|sgd:S000006389|mint:Q06628|dip:DIP-1191N|ensemblfungi:YPR185W(gene)|ensemblfungi:YPR185W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|rcsb pdb:6KBM|rcsb pdb:6KBN|reactome:R-SCE-1632852|go:"GO:0019887"(protein kinase regulator activity)	psi-mi:"MI:0465"(dip)	crc64:71504B6C76549B75	crc64:45CD16F69B795E62	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:cOX1btuNKiBhY8roD022C0NYxG4559292	rogid:Op8+j2qoEeML+DW19641V5t7/js559292	rigid:c/fMrShM4ZDmz/USayRwEOczN+0	false	-	ha tag:c-c|mutation disrupting interaction strength:429-429	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06628	uniprotkb:P53104	intact:EBI-36188|uniprotkb:D6W4I5|ensemblfungi:YPR185W	intact:EBI-2657|uniprotkb:D6VTX3|ensemblfungi:YGL180W	psi-mi:atg13_yeast(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:APG13(gene name synonym)|uniprotkb:YPR185W(locus name)	psi-mi:atg1_yeast(display_long)|uniprotkb:ATG1(gene name)|psi-mi:ATG1(display_short)|uniprotkb:APG1(gene name synonym)|uniprotkb:AUT3(gene name synonym)|uniprotkb:YGL180W(locus name)|uniprotkb:G1615(orf name)|uniprotkb:CVT10(gene name synonym)|uniprotkb:Autophagy-related protein 1(gene name synonym)|uniprotkb:Autophagy protein 3(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 10(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105165|imex:IM-22702-8|dip:DIP-1389E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015511.1|sgd:S000006389|mint:Q06628|dip:DIP-1191N|ensemblfungi:YPR185W(gene)|ensemblfungi:YPR185W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|rcsb pdb:6KBM|rcsb pdb:6KBN|reactome:R-SCE-1632852|go:"GO:0019887"(protein kinase regulator activity)	refseq:NP_011335.1|sgd:S000003148|dip:DIP-1192N|mint:P53104|ensemblfungi:YGL180W(gene)|ensemblfungi:YGL180W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0044805"(late nucleophagy)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0061709"(reticulophagy)|go:"GO:0061908"(phagophore)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|reactome:R-SCE-1632852|reactome:R-SCE-8934903	psi-mi:"MI:0465"(dip)	crc64:45CD16F69B795E62	crc64:7F4C785AA3A7CC46	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:Op8+j2qoEeML+DW19641V5t7/js559292	rogid:b5bLJuCqm9VArsQteYG2dqv+KwA559292	rigid:mQxIJFjX5kHy8rSWW1nxyG4yYLU	false	sufficient binding region:460-491|mutation disrupting interaction strength:472-472,468-468|mutation decreasing interaction strength:468-468	sufficient binding region:587-897	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:W0TA43	uniprotkb:W0T9X4	intact:EBI-16104996|ensemblfungi:BAO40497	intact:EBI-16104970|ensemblfungi:BAO39616	psi-mi:atg13_klumd(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:KLMA_40473(orf name)	psi-mi:atg1_klumd(display_long)|uniprotkb:Autophagy-related protein 1(gene name synonym)|uniprotkb:KLMA_30321(orf name)|uniprotkb:ATG1(gene name)|psi-mi:ATG1(display_short)	psi-mi:"MI:0096"(pull down)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:1003335(kluyveromyces marxianus dmku3-1042)|taxid:1003335(Kluyveromyces marxianus DMKU3-1042)	taxid:1003335(kluyveromyces marxianus dmku3-1042)|taxid:1003335(Kluyveromyces marxianus DMKU3-1042)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105193|imex:IM-22702-9|dip:DIP-196562E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:BAO40497(transcript)|ensemblfungi:KLMA_40473(gene)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|rcsb pdb:4P1N|dip:DIP-60844N	ensemblfungi:BAO39616(transcript)|ensemblfungi:KLMA_30321(gene)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0061709"(reticulophagy)|go:"GO:0061908"(phagophore)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|rcsb pdb:4P1N|go:"GO:0000422"(autophagy of mitochondrion)|dip:DIP-60843N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:gvPAKr5uf/OxApRRfu7pfRtAIj81003335	rogid:DAaYY0sJKcy/l2Oe7FBEfxDnjNI1003335	rigid:ulfV5JvcoQL6WHKZxFxFyGN1Mj8	false	sufficient binding region:441-500	sufficient binding region:566-836|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O70405	uniprotkb:O75143	intact:EBI-8390771|intact:UNK-5365168|uniprotkb:Q6PGB2	intact:EBI-2798775|ensembl:ENSP00000352500|ensembl:ENSP00000431974|uniprotkb:Q9BRL3|uniprotkb:Q9H8B0|uniprotkb:D3DQQ1|uniprotkb:D3DQQ2|uniprotkb:B4DFI4|uniprotkb:E9PQZ8|uniprotkb:Q53EN6|intact:EBI-28977728	psi-mi:ulk1_mouse(display_long)|uniprotkb:Ulk1(gene name)|psi-mi:Ulk1(display_short)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.1(gene name synonym)	psi-mi:atg13_human(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:KIAA0652(gene name synonym)	psi-mi:"MI:0096"(pull down)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105216|imex:IM-22702-10|dip:DIP-196563E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033495.2|dip:DIP-60541N|mint:O70405|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021933"(radial glia guided migration of cerebellar granule cell)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR022708|reactome:R-MMU-1632852|reactome:R-MMU-8854214|reactome:R-MMU-8876198|reactome:R-MMU-8934903|interpro:IPR017441(Protein kinase ATP binding, conserved site)	ensembl:ENSG00000175224(gene)|ensembl:ENST00000359513(transcript)|ensembl:ENST00000526508(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|mint:O75143|refseq:NP_001333240.1|refseq:NP_001333241.1|refseq:NP_001333242.1|refseq:NP_001333243.1|refseq:NP_001333244.1|refseq:NP_001333245.1|refseq:NP_001333248.1|refseq:NP_001333249.1|refseq:NP_001333250.1|ensembl:ENSP00000352500|ensembl:ENST00000524625|ensembl:ENSP00000433543|ensembl:ENSP00000431974|ensembl:ENST00000528494|ensembl:ENSP00000432412|ensembl:ENST00000529655|ensembl:ENSP00000433756|ensembl:ENST00000530500|ensembl:ENSP00000434390|ensembl:ENST00000683050|ensembl:ENSP00000507809|refseq:NP_001333251.1|refseq:XP_011518795.1|refseq:XP_011518798.1|refseq:XP_011518801.1|refseq:NP_001136145.1|refseq:NP_001192048.1|refseq:NP_001192049.1|refseq:NP_001192050.1|refseq:NP_001192051.1|refseq:NP_055556.2|refseq:NP_001333271.1|refseq:XP_016874088.1|refseq:XP_016874092.1|refseq:XP_016874096.1|refseq:NP_001333252.1|refseq:NP_001333253.1|refseq:NP_001333254.1|refseq:NP_001333255.1|refseq:NP_001333256.1|refseq:NP_001333257.1|refseq:NP_001333258.1|refseq:NP_001333259.1|refseq:NP_001333260.1|refseq:NP_001333261.1|refseq:XP_006718459.1|refseq:XP_005253322.1|refseq:XP_005253323.1|refseq:XP_005253325.1|refseq:NP_001333273.1|refseq:NP_001333275.1|refseq:NP_001333277.1|refseq:NP_001333278.1|refseq:NP_001333279.1|refseq:NP_001333280.1|refseq:NP_001333281.1|refseq:NP_001333282.1|refseq:NP_001333283.1|dip:DIP-60540N|rcsb pdb:3WAO|rcsb pdb:3WAP|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|rcsb pdb:6HYN|reactome:R-HSA-1632852|rcsb pdb:3WAN	psi-mi:"MI:0465"(dip)	comment:mint|comment:homomint|function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:mLPj6Pp1VXGMixWyd7MygI4VgPo10090	rogid:xlABwrglkoQu3OSb/8yLTQVxN8o9606	rigid:HBMQJ8xpQr5n1xx/qn5YN+3Yo+M	false	sufficient binding region:834-1051	sufficient binding region:458-517|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q06410	uniprotkb:Q06628	intact:EBI-30856|uniprotkb:D6VZ59|ensemblfungi:YLR423C	intact:EBI-36188|uniprotkb:D6W4I5|ensemblfungi:YPR185W	psi-mi:atg17_yeast(display_long)|uniprotkb:ATG17(gene name)|psi-mi:ATG17(display_short)|uniprotkb:APG17(gene name synonym)|uniprotkb:YLR423C(locus name)	psi-mi:atg13_yeast(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:APG13(gene name synonym)|uniprotkb:YPR185W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105239|imex:IM-22702-11|dip:DIP-185611E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004415|refseq:NP_013527.3|dip:DIP-1490N|mint:Q06410|ensemblfungi:YLR423C(gene)|ensemblfungi:YLR423C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0045772"(positive regulation of autophagosome size)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR007240(Autophagy protein 17)	refseq:NP_015511.1|sgd:S000006389|mint:Q06628|dip:DIP-1191N|ensemblfungi:YPR185W(gene)|ensemblfungi:YPR185W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|rcsb pdb:6KBM|rcsb pdb:6KBN|reactome:R-SCE-1632852|go:"GO:0019887"(protein kinase regulator activity)	psi-mi:"MI:0465"(dip)	crc64:71504B6C76549B75	crc64:45CD16F69B795E62	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:cOX1btuNKiBhY8roD022C0NYxG4559292	rogid:Op8+j2qoEeML+DW19641V5t7/js559292	rigid:c/fMrShM4ZDmz/USayRwEOczN+0	false	mutation disrupting interaction strength:247-247	green fluorescent protein tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q06628	uniprotkb:P53104	intact:EBI-36188|uniprotkb:D6W4I5|ensemblfungi:YPR185W	intact:EBI-2657|uniprotkb:D6VTX3|ensemblfungi:YGL180W	psi-mi:atg13_yeast(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:APG13(gene name synonym)|uniprotkb:YPR185W(locus name)	psi-mi:atg1_yeast(display_long)|uniprotkb:ATG1(gene name)|psi-mi:ATG1(display_short)|uniprotkb:APG1(gene name synonym)|uniprotkb:AUT3(gene name synonym)|uniprotkb:YGL180W(locus name)|uniprotkb:G1615(orf name)|uniprotkb:CVT10(gene name synonym)|uniprotkb:Autophagy-related protein 1(gene name synonym)|uniprotkb:Autophagy protein 3(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105261|imex:IM-22702-12|dip:DIP-1389E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015511.1|sgd:S000006389|mint:Q06628|dip:DIP-1191N|ensemblfungi:YPR185W(gene)|ensemblfungi:YPR185W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|rcsb pdb:6KBM|rcsb pdb:6KBN|reactome:R-SCE-1632852|go:"GO:0019887"(protein kinase regulator activity)	refseq:NP_011335.1|sgd:S000003148|dip:DIP-1192N|mint:P53104|ensemblfungi:YGL180W(gene)|ensemblfungi:YGL180W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0044805"(late nucleophagy)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0061709"(reticulophagy)|go:"GO:0061908"(phagophore)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|reactome:R-SCE-1632852|reactome:R-SCE-8934903	psi-mi:"MI:0465"(dip)	crc64:45CD16F69B795E62	crc64:7F4C785AA3A7CC46	comment:Deletion of region 492-521 decreased the interaction rate/strength.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:Op8+j2qoEeML+DW19641V5t7/js559292	rogid:b5bLJuCqm9VArsQteYG2dqv+KwA559292	rigid:mQxIJFjX5kHy8rSWW1nxyG4yYLU	false	necessary binding region:460-491|mutation disrupting interaction strength:472-472,468-468|mutation disrupting interaction strength:468-468|mutation disrupting interaction strength:472-472	green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06410	uniprotkb:Q06628	intact:EBI-30856|uniprotkb:D6VZ59|ensemblfungi:YLR423C	intact:EBI-36188|uniprotkb:D6W4I5|ensemblfungi:YPR185W	psi-mi:atg17_yeast(display_long)|uniprotkb:ATG17(gene name)|psi-mi:ATG17(display_short)|uniprotkb:APG17(gene name synonym)|uniprotkb:YLR423C(locus name)	psi-mi:atg13_yeast(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:APG13(gene name synonym)|uniprotkb:YPR185W(locus name)	psi-mi:"MI:0096"(pull down)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105293|imex:IM-22702-13|dip:DIP-185611E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004415|refseq:NP_013527.3|dip:DIP-1490N|mint:Q06410|ensemblfungi:YLR423C(gene)|ensemblfungi:YLR423C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0045772"(positive regulation of autophagosome size)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR007240(Autophagy protein 17)	refseq:NP_015511.1|sgd:S000006389|mint:Q06628|dip:DIP-1191N|ensemblfungi:YPR185W(gene)|ensemblfungi:YPR185W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|rcsb pdb:6KBM|rcsb pdb:6KBN|reactome:R-SCE-1632852|go:"GO:0019887"(protein kinase regulator activity)	psi-mi:"MI:0465"(dip)	crc64:71504B6C76549B75	crc64:45CD16F69B795E62	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:cOX1btuNKiBhY8roD022C0NYxG4559292	rogid:Op8+j2qoEeML+DW19641V5t7/js559292	rigid:c/fMrShM4ZDmz/USayRwEOczN+0	false	-	sufficient binding region:424-436|glutathione s tranferase tag:n-n|mutation disrupting interaction strength:429-429,428-428|mutation disrupting interaction strength:433-433,430-430|mutation disrupting interaction strength:435-435,434-434|mutation disrupting interaction strength:429-429	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:C5DF24	uniprotkb:C5DEB9	intact:EBI-6558893|ensemblfungi:CAR22779	intact:EBI-6558887|ensemblfungi:CAR22130	psi-mi:c5df24_lactc(display_long)|uniprotkb:KLTH0D11660g(locus name)	psi-mi:c5deb9_lactc(display_long)|uniprotkb:KLTH0C07942g(locus name)	psi-mi:"MI:0096"(pull down)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:559295(lactc)|taxid:559295("Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)")	taxid:559295(lactc)|taxid:559295("Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105373|imex:IM-22702-15|dip:DIP-196565E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:CAR22779(transcript)|ensemblfungi:KLTH0D11660g(gene)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0015031"(protein transport)|interpro:IPR039113|interpro:IPR039362|interpro:IPR040666|rcsb pdb:4HPQ|rcsb pdb:4P1W|rcsb pdb:5JHF|refseq:XP_002553217.1|dip:DIP-60847N	ensemblfungi:CAR22130(transcript)|ensemblfungi:KLTH0C07942g(gene)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0006914"(autophagy)|interpro:IPR018621|rcsb pdb:4HPQ|rcsb pdb:4P1W|rcsb pdb:5JHF|refseq:XP_002552568.1|dip:DIP-60846N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:o9DlnsaFIbWVsQRGlbJOXwJ6eCk559295	rogid:jIaKEbr59vcj7dtkME3Rdr9Er64559295	rigid:hyHYu6AXJBdM8I9lLWkRWIBbpcc	false	his tag:n-n	sufficient binding region:1-86	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:C5DF24	uniprotkb:C5DFJ6	intact:EBI-6558893|ensemblfungi:CAR22779	intact:EBI-6558880|ensemblfungi:CAR22951	psi-mi:c5df24_lactc(display_long)|uniprotkb:KLTH0D11660g(locus name)	psi-mi:c5dfj6_lactc(display_long)|uniprotkb:KLTH0D15642g(locus name)	psi-mi:"MI:0096"(pull down)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:559295(lactc)|taxid:559295("Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)")	taxid:559295(lactc)|taxid:559295("Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105373|imex:IM-22702-15|dip:DIP-196565E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:CAR22779(transcript)|ensemblfungi:KLTH0D11660g(gene)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0015031"(protein transport)|interpro:IPR039113|interpro:IPR039362|interpro:IPR040666|rcsb pdb:4HPQ|rcsb pdb:4P1W|rcsb pdb:5JHF|refseq:XP_002553217.1|dip:DIP-60847N	ensemblfungi:CAR22951(transcript)|ensemblfungi:KLTH0D15642g(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|interpro:IPR007240(Autophagy protein 17)|rcsb pdb:4HPQ|rcsb pdb:4P1W|rcsb pdb:5JHF|refseq:XP_002553389.1|dip:DIP-60845N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/08	2017/08/10	rogid:o9DlnsaFIbWVsQRGlbJOXwJ6eCk559295	rogid:QBDi57c3zpd7P52vitMh9KxNqbg559295	rigid:hyHYu6AXJBdM8I9lLWkRWIBbpcc	false	his tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:C5DB94	uniprotkb:C5DEB9	intact:EBI-16105330|ensemblfungi:CAR21051	intact:EBI-6558887|ensemblfungi:CAR22130	psi-mi:c5db94_lactc(display_long)|uniprotkb:KLTH0A00704g(locus name)	psi-mi:c5deb9_lactc(display_long)|uniprotkb:KLTH0C07942g(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:559295(lactc)|taxid:559295("Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)")	taxid:559295(lactc)|taxid:559295("Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105350|imex:IM-22702-14|dip:DIP-196564E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:CAR21051(transcript)|ensemblfungi:KLTH0A00704g(gene)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|rcsb pdb:4J2G|rcsb pdb:4P1W|rcsb pdb:5JHF|refseq:XP_002551493.1|dip:DIP-60848N	ensemblfungi:CAR22130(transcript)|ensemblfungi:KLTH0C07942g(gene)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0006914"(autophagy)|interpro:IPR018621|rcsb pdb:4HPQ|rcsb pdb:4P1W|rcsb pdb:5JHF|refseq:XP_002552568.1|dip:DIP-60846N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:dQ9/9RmVZyPkBphI34cHURlQlfI559295	rogid:jIaKEbr59vcj7dtkME3Rdr9Er64559295	rigid:5femnx/BaSz2zEQWLAGc6Pk2aGM	false	sufficient binding region:392-404	sufficient binding region:1-86	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:C5DB94	uniprotkb:C5DF24	intact:EBI-16105330|ensemblfungi:CAR21051	intact:EBI-6558893|ensemblfungi:CAR22779	psi-mi:c5db94_lactc(display_long)|uniprotkb:KLTH0A00704g(locus name)	psi-mi:c5df24_lactc(display_long)|uniprotkb:KLTH0D11660g(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:559295(lactc)|taxid:559295("Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)")	taxid:559295(lactc)|taxid:559295("Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105350|imex:IM-22702-14|dip:DIP-196564E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:CAR21051(transcript)|ensemblfungi:KLTH0A00704g(gene)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|rcsb pdb:4J2G|rcsb pdb:4P1W|rcsb pdb:5JHF|refseq:XP_002551493.1|dip:DIP-60848N	ensemblfungi:CAR22779(transcript)|ensemblfungi:KLTH0D11660g(gene)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0015031"(protein transport)|interpro:IPR039113|interpro:IPR039362|interpro:IPR040666|rcsb pdb:4HPQ|rcsb pdb:4P1W|rcsb pdb:5JHF|refseq:XP_002553217.1|dip:DIP-60847N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:dQ9/9RmVZyPkBphI34cHURlQlfI559295	rogid:o9DlnsaFIbWVsQRGlbJOXwJ6eCk559295	rigid:5femnx/BaSz2zEQWLAGc6Pk2aGM	false	sufficient binding region:392-404	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:C5DB94	uniprotkb:C5DFJ6	intact:EBI-16105330|ensemblfungi:CAR21051	intact:EBI-6558880|ensemblfungi:CAR22951	psi-mi:c5db94_lactc(display_long)|uniprotkb:KLTH0A00704g(locus name)	psi-mi:c5dfj6_lactc(display_long)|uniprotkb:KLTH0D15642g(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:559295(lactc)|taxid:559295("Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)")	taxid:559295(lactc)|taxid:559295("Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105350|imex:IM-22702-14|dip:DIP-196564E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:CAR21051(transcript)|ensemblfungi:KLTH0A00704g(gene)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|rcsb pdb:4J2G|rcsb pdb:4P1W|rcsb pdb:5JHF|refseq:XP_002551493.1|dip:DIP-60848N	ensemblfungi:CAR22951(transcript)|ensemblfungi:KLTH0D15642g(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|interpro:IPR007240(Autophagy protein 17)|rcsb pdb:4HPQ|rcsb pdb:4P1W|rcsb pdb:5JHF|refseq:XP_002553389.1|dip:DIP-60845N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:dQ9/9RmVZyPkBphI34cHURlQlfI559295	rogid:QBDi57c3zpd7P52vitMh9KxNqbg559295	rigid:5femnx/BaSz2zEQWLAGc6Pk2aGM	false	sufficient binding region:392-404	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06410	uniprotkb:Q06628	intact:EBI-30856|uniprotkb:D6VZ59|ensemblfungi:YLR423C	intact:EBI-36188|uniprotkb:D6W4I5|ensemblfungi:YPR185W	psi-mi:atg17_yeast(display_long)|uniprotkb:ATG17(gene name)|psi-mi:ATG17(display_short)|uniprotkb:APG17(gene name synonym)|uniprotkb:YLR423C(locus name)	psi-mi:atg13_yeast(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:APG13(gene name synonym)|uniprotkb:YPR185W(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Fujioka et al. (2014)	pubmed:24793651|doi:10.1038/nsmb.2822|imex:IM-22702	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16105395|imex:IM-22702-16|dip:DIP-185611E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004415|refseq:NP_013527.3|dip:DIP-1490N|mint:Q06410|ensemblfungi:YLR423C(gene)|ensemblfungi:YLR423C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0045772"(positive regulation of autophagosome size)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR007240(Autophagy protein 17)	refseq:NP_015511.1|sgd:S000006389|mint:Q06628|dip:DIP-1191N|ensemblfungi:YPR185W(gene)|ensemblfungi:YPR185W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|rcsb pdb:6KBM|rcsb pdb:6KBN|reactome:R-SCE-1632852|go:"GO:0019887"(protein kinase regulator activity)	psi-mi:"MI:0465"(dip)	crc64:71504B6C76549B75	crc64:45CD16F69B795E62	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:cOX1btuNKiBhY8roD022C0NYxG4559292	rogid:Op8+j2qoEeML+DW19641V5t7/js559292	rigid:c/fMrShM4ZDmz/USayRwEOczN+0	false	mutation disrupting interaction strength:247-247|mutation disrupting interaction strength:250-250,247-247	sufficient binding region:424-436	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)