#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q7L1W4	uniprotkb:Q8IWT6	intact:EBI-861997|uniprotkb:Q6UWB2|uniprotkb:Q9NVW3|uniprotkb:D3DT29|ensembl:ENSP00000338887|ensembl:ENSP00000378093	intact:EBI-10970086|ensembl:ENSP00000259324|ensembl:ENSP00000361680|ensembl:ENSP00000361682|uniprotkb:Q9P2B1|uniprotkb:Q8NCI0|uniprotkb:Q6UXM2	psi-mi:lrc8d_human(display_long)|uniprotkb:Leucine-rich repeat-containing protein 8D(gene name synonym)|uniprotkb:UNQ213/PRO239(orf name)|uniprotkb:LRRC8D(gene name)|psi-mi:LRRC8D(display_short)|uniprotkb:LRRC5(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 5(gene name synonym)	psi-mi:lrc8a_human(display_long)|uniprotkb:LRRC8A(gene name)|psi-mi:LRRC8A(display_short)|uniprotkb:KIAA1437(gene name synonym)|uniprotkb:LRRC8(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 8A(gene name synonym)|uniprotkb:SWELL1(gene name synonym)|uniprotkb:Swelling protein 1(gene name synonym)|uniprotkb:UNQ221/PRO247(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Voss et al. (2014)	pubmed:24790029|doi:"https://doi.org/10.1126/science.1252826"|imex:IM-24117	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104513|imex:IM-24117-1|dip:DIP-198641E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127951.1|refseq:NP_060573.2|refseq:XP_016857088.1|refseq:XP_016857089.1|refseq:XP_016857090.1|refseq:XP_016857091.1|refseq:XP_011539991.1|dip:DIP-31280N|ensembl:ENSG00000171492(gene)|ensembl:ENST00000337338(transcript)|ensembl:ENST00000394593(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0098656"(anion transmembrane transport)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR032675|rcsb pdb:6M04|reactome:R-HSA-5223345	refseq:NP_001120716.1|refseq:NP_001120717.1|refseq:NP_062540.2|refseq:XP_005252152.1|refseq:XP_005252153.1|refseq:XP_006717249.1|refseq:XP_011517165.1|refseq:XP_011517166.1|refseq:XP_011517167.1|ensembl:ENSG00000136802(gene)|ensembl:ENST00000259324(transcript)|ensembl:ENST00000372599(transcript)|ensembl:ENST00000372600(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140360"(cyclic-GMP-AMP transmembrane transporter activity)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR032675|mint:Q8IWT6|rcsb pdb:5ZSU|rcsb pdb:6DJB|reactome:R-HSA-5223345|dip:DIP-61360N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:ufVPVQVTeiRGQwGw/VFY2BlXRvk9606	rogid:4+VhpXqOjBfbrNagOqJ7eY/qy+s9606	rigid:OcKba2KOQrcSn0UyyH0clm0lqfk	false	green fluorescent protein tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7L1W4	uniprotkb:Q8IWT6	intact:EBI-861997|uniprotkb:Q6UWB2|uniprotkb:Q9NVW3|uniprotkb:D3DT29|ensembl:ENSP00000338887|ensembl:ENSP00000378093	intact:EBI-10970086|ensembl:ENSP00000259324|ensembl:ENSP00000361680|ensembl:ENSP00000361682|uniprotkb:Q9P2B1|uniprotkb:Q8NCI0|uniprotkb:Q6UXM2	psi-mi:lrc8d_human(display_long)|uniprotkb:Leucine-rich repeat-containing protein 8D(gene name synonym)|uniprotkb:UNQ213/PRO239(orf name)|uniprotkb:LRRC8D(gene name)|psi-mi:LRRC8D(display_short)|uniprotkb:LRRC5(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 5(gene name synonym)	psi-mi:lrc8a_human(display_long)|uniprotkb:LRRC8A(gene name)|psi-mi:LRRC8A(display_short)|uniprotkb:KIAA1437(gene name synonym)|uniprotkb:LRRC8(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 8A(gene name synonym)|uniprotkb:SWELL1(gene name synonym)|uniprotkb:Swelling protein 1(gene name synonym)|uniprotkb:UNQ221/PRO247(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Voss et al. (2014)	pubmed:24790029|doi:"https://doi.org/10.1126/science.1252826"|imex:IM-24117	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104549|imex:IM-24117-3|dip:DIP-198641E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127951.1|refseq:NP_060573.2|refseq:XP_016857088.1|refseq:XP_016857089.1|refseq:XP_016857090.1|refseq:XP_016857091.1|refseq:XP_011539991.1|dip:DIP-31280N|ensembl:ENSG00000171492(gene)|ensembl:ENST00000337338(transcript)|ensembl:ENST00000394593(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0098656"(anion transmembrane transport)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR032675|rcsb pdb:6M04|reactome:R-HSA-5223345	refseq:NP_001120716.1|refseq:NP_001120717.1|refseq:NP_062540.2|refseq:XP_005252152.1|refseq:XP_005252153.1|refseq:XP_006717249.1|refseq:XP_011517165.1|refseq:XP_011517166.1|refseq:XP_011517167.1|ensembl:ENSG00000136802(gene)|ensembl:ENST00000259324(transcript)|ensembl:ENST00000372599(transcript)|ensembl:ENST00000372600(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140360"(cyclic-GMP-AMP transmembrane transporter activity)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR032675|mint:Q8IWT6|rcsb pdb:5ZSU|rcsb pdb:6DJB|reactome:R-HSA-5223345|dip:DIP-61360N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:ufVPVQVTeiRGQwGw/VFY2BlXRvk9606	rogid:4+VhpXqOjBfbrNagOqJ7eY/qy+s9606	rigid:OcKba2KOQrcSn0UyyH0clm0lqfk	false	green fluorescent protein tag:n-n	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q6NSJ5	uniprotkb:Q8IWT6	intact:EBI-8647013|ensembl:ENSP00000306524|ensembl:ENSP00000479953|uniprotkb:Q7L236|uniprotkb:Q8N3B0|uniprotkb:Q2YDY3|uniprotkb:Q9H5H8|uniprotkb:B3KR78|intact:MINT-8163602	intact:EBI-10970086|ensembl:ENSP00000259324|ensembl:ENSP00000361680|ensembl:ENSP00000361682|uniprotkb:Q9P2B1|uniprotkb:Q8NCI0|uniprotkb:Q6UXM2	psi-mi:lrc8e_human(display_long)|uniprotkb:LRRC8E(gene name)|psi-mi:LRRC8E(display_short)|uniprotkb:Leucine-rich repeat-containing protein 8E(gene name synonym)	psi-mi:lrc8a_human(display_long)|uniprotkb:LRRC8A(gene name)|psi-mi:LRRC8A(display_short)|uniprotkb:KIAA1437(gene name synonym)|uniprotkb:LRRC8(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 8A(gene name synonym)|uniprotkb:SWELL1(gene name synonym)|uniprotkb:Swelling protein 1(gene name synonym)|uniprotkb:UNQ221/PRO247(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Voss et al. (2014)	pubmed:24790029|doi:"https://doi.org/10.1126/science.1252826"|imex:IM-24117	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104532|imex:IM-24117-2|dip:DIP-198637E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171017(gene)|ensembl:ENST00000306708(transcript)|ensembl:ENST00000618098(transcript)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034702"(ion channel complex)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|reactome:R-HSA-5223345|interpro:IPR032675|refseq:XP_011526621.1|refseq:NP_001255213.1|refseq:NP_079337.2|refseq:NP_001255214.1|dip:DIP-61363N	refseq:NP_001120716.1|refseq:NP_001120717.1|refseq:NP_062540.2|refseq:XP_005252152.1|refseq:XP_005252153.1|refseq:XP_006717249.1|refseq:XP_011517165.1|refseq:XP_011517166.1|refseq:XP_011517167.1|ensembl:ENSG00000136802(gene)|ensembl:ENST00000259324(transcript)|ensembl:ENST00000372599(transcript)|ensembl:ENST00000372600(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140360"(cyclic-GMP-AMP transmembrane transporter activity)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR032675|mint:Q8IWT6|rcsb pdb:5ZSU|rcsb pdb:6DJB|reactome:R-HSA-5223345|dip:DIP-61360N	psi-mi:"MI:0465"(dip)	comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:pQHkswfwifVqchBKu1+iMkt+0qo9606	rogid:4+VhpXqOjBfbrNagOqJ7eY/qy+s9606	rigid:Ia2FNocXcf0dlq/KOYA/enpk2Hc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6P9F7	uniprotkb:Q8IWT6	intact:EBI-9477617|uniprotkb:Q92627|uniprotkb:Q8N106|uniprotkb:D3DT28|uniprotkb:Q6UY21|ensembl:ENSP00000332674|ensembl:ENSP00000491377|ensembl:ENSP00000492151	intact:EBI-10970086|ensembl:ENSP00000259324|ensembl:ENSP00000361680|ensembl:ENSP00000361682|uniprotkb:Q9P2B1|uniprotkb:Q8NCI0|uniprotkb:Q6UXM2	psi-mi:lrc8b_human(display_long)|uniprotkb:LRRC8B(gene name)|psi-mi:LRRC8B(display_short)|uniprotkb:Leucine-rich repeat-containing protein 8B(gene name synonym)|uniprotkb:KIAA0231(gene name synonym)|uniprotkb:T-cell activation leucine repeat-rich protein(gene name synonym)|uniprotkb:UNQ6413/PRO21207(orf name)	psi-mi:lrc8a_human(display_long)|uniprotkb:LRRC8A(gene name)|psi-mi:LRRC8A(display_short)|uniprotkb:KIAA1437(gene name synonym)|uniprotkb:LRRC8(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 8A(gene name synonym)|uniprotkb:SWELL1(gene name synonym)|uniprotkb:Swelling protein 1(gene name synonym)|uniprotkb:UNQ221/PRO247(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Voss et al. (2014)	pubmed:24790029|doi:"https://doi.org/10.1126/science.1252826"|imex:IM-24117	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104570|imex:IM-24117-4|dip:DIP-198639E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011539445.1|refseq:XP_011539446.1|refseq:XP_011539447.1|refseq:XP_011539448.1|refseq:XP_016856372.1|refseq:XP_016856373.1|refseq:XP_016856374.1|refseq:NP_001127948.1|refseq:NP_056165.1|refseq:XP_005270758.1|refseq:XP_005270759.1|refseq:XP_005270760.1|dip:DIP-61361N|ensembl:ENSG00000197147(gene)|ensembl:ENST00000330947(transcript)|ensembl:ENST00000639264(transcript)|ensembl:ENST00000640258(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015698"(inorganic anion transport)|go:"GO:0034702"(ion channel complex)|go:"GO:0098656"(anion transmembrane transport)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR026906|interpro:IPR032675|reactome:R-HSA-5223345	refseq:NP_001120716.1|refseq:NP_001120717.1|refseq:NP_062540.2|refseq:XP_005252152.1|refseq:XP_005252153.1|refseq:XP_006717249.1|refseq:XP_011517165.1|refseq:XP_011517166.1|refseq:XP_011517167.1|ensembl:ENSG00000136802(gene)|ensembl:ENST00000259324(transcript)|ensembl:ENST00000372599(transcript)|ensembl:ENST00000372600(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140360"(cyclic-GMP-AMP transmembrane transporter activity)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR032675|mint:Q8IWT6|rcsb pdb:5ZSU|rcsb pdb:6DJB|reactome:R-HSA-5223345|dip:DIP-61360N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:QlA1G8RWBlSD2IaaRuCuUA1VQvg9606	rogid:4+VhpXqOjBfbrNagOqJ7eY/qy+s9606	rigid:W1RxuPqoB4XoyppX/1ZEKA5IgdE	false	green fluorescent protein tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6P9F7	uniprotkb:Q8IWT6	intact:EBI-9477617|uniprotkb:Q92627|uniprotkb:Q8N106|uniprotkb:D3DT28|uniprotkb:Q6UY21|ensembl:ENSP00000332674|ensembl:ENSP00000491377|ensembl:ENSP00000492151	intact:EBI-10970086|ensembl:ENSP00000259324|ensembl:ENSP00000361680|ensembl:ENSP00000361682|uniprotkb:Q9P2B1|uniprotkb:Q8NCI0|uniprotkb:Q6UXM2	psi-mi:lrc8b_human(display_long)|uniprotkb:LRRC8B(gene name)|psi-mi:LRRC8B(display_short)|uniprotkb:Leucine-rich repeat-containing protein 8B(gene name synonym)|uniprotkb:KIAA0231(gene name synonym)|uniprotkb:T-cell activation leucine repeat-rich protein(gene name synonym)|uniprotkb:UNQ6413/PRO21207(orf name)	psi-mi:lrc8a_human(display_long)|uniprotkb:LRRC8A(gene name)|psi-mi:LRRC8A(display_short)|uniprotkb:KIAA1437(gene name synonym)|uniprotkb:LRRC8(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 8A(gene name synonym)|uniprotkb:SWELL1(gene name synonym)|uniprotkb:Swelling protein 1(gene name synonym)|uniprotkb:UNQ221/PRO247(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Voss et al. (2014)	pubmed:24790029|doi:"https://doi.org/10.1126/science.1252826"|imex:IM-24117	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104589|imex:IM-24117-5|dip:DIP-198639E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011539445.1|refseq:XP_011539446.1|refseq:XP_011539447.1|refseq:XP_011539448.1|refseq:XP_016856372.1|refseq:XP_016856373.1|refseq:XP_016856374.1|refseq:NP_001127948.1|refseq:NP_056165.1|refseq:XP_005270758.1|refseq:XP_005270759.1|refseq:XP_005270760.1|dip:DIP-61361N|ensembl:ENSG00000197147(gene)|ensembl:ENST00000330947(transcript)|ensembl:ENST00000639264(transcript)|ensembl:ENST00000640258(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015698"(inorganic anion transport)|go:"GO:0034702"(ion channel complex)|go:"GO:0098656"(anion transmembrane transport)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR026906|interpro:IPR032675|reactome:R-HSA-5223345	refseq:NP_001120716.1|refseq:NP_001120717.1|refseq:NP_062540.2|refseq:XP_005252152.1|refseq:XP_005252153.1|refseq:XP_006717249.1|refseq:XP_011517165.1|refseq:XP_011517166.1|refseq:XP_011517167.1|ensembl:ENSG00000136802(gene)|ensembl:ENST00000259324(transcript)|ensembl:ENST00000372599(transcript)|ensembl:ENST00000372600(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140360"(cyclic-GMP-AMP transmembrane transporter activity)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR032675|mint:Q8IWT6|rcsb pdb:5ZSU|rcsb pdb:6DJB|reactome:R-HSA-5223345|dip:DIP-61360N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:QlA1G8RWBlSD2IaaRuCuUA1VQvg9606	rogid:4+VhpXqOjBfbrNagOqJ7eY/qy+s9606	rigid:W1RxuPqoB4XoyppX/1ZEKA5IgdE	false	green fluorescent protein tag:n-n	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q6NSJ5	uniprotkb:Q8IWT6	intact:EBI-8647013|ensembl:ENSP00000306524|ensembl:ENSP00000479953|uniprotkb:Q7L236|uniprotkb:Q8N3B0|uniprotkb:Q2YDY3|uniprotkb:Q9H5H8|uniprotkb:B3KR78|intact:MINT-8163602	intact:EBI-10970086|ensembl:ENSP00000259324|ensembl:ENSP00000361680|ensembl:ENSP00000361682|uniprotkb:Q9P2B1|uniprotkb:Q8NCI0|uniprotkb:Q6UXM2	psi-mi:lrc8e_human(display_long)|uniprotkb:LRRC8E(gene name)|psi-mi:LRRC8E(display_short)|uniprotkb:Leucine-rich repeat-containing protein 8E(gene name synonym)	psi-mi:lrc8a_human(display_long)|uniprotkb:LRRC8A(gene name)|psi-mi:LRRC8A(display_short)|uniprotkb:KIAA1437(gene name synonym)|uniprotkb:LRRC8(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 8A(gene name synonym)|uniprotkb:SWELL1(gene name synonym)|uniprotkb:Swelling protein 1(gene name synonym)|uniprotkb:UNQ221/PRO247(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Voss et al. (2014)	pubmed:24790029|doi:"https://doi.org/10.1126/science.1252826"|imex:IM-24117	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104610|imex:IM-24117-6|dip:DIP-198637E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171017(gene)|ensembl:ENST00000306708(transcript)|ensembl:ENST00000618098(transcript)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034702"(ion channel complex)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|reactome:R-HSA-5223345|interpro:IPR032675|refseq:XP_011526621.1|refseq:NP_001255213.1|refseq:NP_079337.2|refseq:NP_001255214.1|dip:DIP-61363N	refseq:NP_001120716.1|refseq:NP_001120717.1|refseq:NP_062540.2|refseq:XP_005252152.1|refseq:XP_005252153.1|refseq:XP_006717249.1|refseq:XP_011517165.1|refseq:XP_011517166.1|refseq:XP_011517167.1|ensembl:ENSG00000136802(gene)|ensembl:ENST00000259324(transcript)|ensembl:ENST00000372599(transcript)|ensembl:ENST00000372600(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140360"(cyclic-GMP-AMP transmembrane transporter activity)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR032675|mint:Q8IWT6|rcsb pdb:5ZSU|rcsb pdb:6DJB|reactome:R-HSA-5223345|dip:DIP-61360N	psi-mi:"MI:0465"(dip)	comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:pQHkswfwifVqchBKu1+iMkt+0qo9606	rogid:4+VhpXqOjBfbrNagOqJ7eY/qy+s9606	rigid:Ia2FNocXcf0dlq/KOYA/enpk2Hc	false	green fluorescent protein tag:n-n	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8IWT6	uniprotkb:Q8IWT6	intact:EBI-10970086|ensembl:ENSP00000259324|ensembl:ENSP00000361680|ensembl:ENSP00000361682|uniprotkb:Q9P2B1|uniprotkb:Q8NCI0|uniprotkb:Q6UXM2	intact:EBI-10970086|ensembl:ENSP00000259324|ensembl:ENSP00000361680|ensembl:ENSP00000361682|uniprotkb:Q9P2B1|uniprotkb:Q8NCI0|uniprotkb:Q6UXM2	psi-mi:lrc8a_human(display_long)|uniprotkb:LRRC8A(gene name)|psi-mi:LRRC8A(display_short)|uniprotkb:KIAA1437(gene name synonym)|uniprotkb:LRRC8(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 8A(gene name synonym)|uniprotkb:SWELL1(gene name synonym)|uniprotkb:Swelling protein 1(gene name synonym)|uniprotkb:UNQ221/PRO247(orf name)	psi-mi:lrc8a_human(display_long)|uniprotkb:LRRC8A(gene name)|psi-mi:LRRC8A(display_short)|uniprotkb:KIAA1437(gene name synonym)|uniprotkb:LRRC8(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 8A(gene name synonym)|uniprotkb:SWELL1(gene name synonym)|uniprotkb:Swelling protein 1(gene name synonym)|uniprotkb:UNQ221/PRO247(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Voss et al. (2014)	pubmed:24790029|doi:"https://doi.org/10.1126/science.1252826"|imex:IM-24117	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104631|imex:IM-24117-7|dip:DIP-198638E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120716.1|refseq:NP_001120717.1|refseq:NP_062540.2|refseq:XP_005252152.1|refseq:XP_005252153.1|refseq:XP_006717249.1|refseq:XP_011517165.1|refseq:XP_011517166.1|refseq:XP_011517167.1|ensembl:ENSG00000136802(gene)|ensembl:ENST00000259324(transcript)|ensembl:ENST00000372599(transcript)|ensembl:ENST00000372600(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140360"(cyclic-GMP-AMP transmembrane transporter activity)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR032675|mint:Q8IWT6|rcsb pdb:5ZSU|rcsb pdb:6DJB|reactome:R-HSA-5223345|dip:DIP-61360N	refseq:NP_001120716.1|refseq:NP_001120717.1|refseq:NP_062540.2|refseq:XP_005252152.1|refseq:XP_005252153.1|refseq:XP_006717249.1|refseq:XP_011517165.1|refseq:XP_011517166.1|refseq:XP_011517167.1|ensembl:ENSG00000136802(gene)|ensembl:ENST00000259324(transcript)|ensembl:ENST00000372599(transcript)|ensembl:ENST00000372600(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140360"(cyclic-GMP-AMP transmembrane transporter activity)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR032675|mint:Q8IWT6|rcsb pdb:5ZSU|rcsb pdb:6DJB|reactome:R-HSA-5223345|dip:DIP-61360N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:4+VhpXqOjBfbrNagOqJ7eY/qy+s9606	rogid:4+VhpXqOjBfbrNagOqJ7eY/qy+s9606	rigid:dxDFXGVmuWpvcVchClcWDehcft0	false	green fluorescent protein tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IWT6	uniprotkb:Q8IWT6	intact:EBI-10970086|ensembl:ENSP00000259324|ensembl:ENSP00000361680|ensembl:ENSP00000361682|uniprotkb:Q9P2B1|uniprotkb:Q8NCI0|uniprotkb:Q6UXM2	intact:EBI-10970086|ensembl:ENSP00000259324|ensembl:ENSP00000361680|ensembl:ENSP00000361682|uniprotkb:Q9P2B1|uniprotkb:Q8NCI0|uniprotkb:Q6UXM2	psi-mi:lrc8a_human(display_long)|uniprotkb:LRRC8A(gene name)|psi-mi:LRRC8A(display_short)|uniprotkb:KIAA1437(gene name synonym)|uniprotkb:LRRC8(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 8A(gene name synonym)|uniprotkb:SWELL1(gene name synonym)|uniprotkb:Swelling protein 1(gene name synonym)|uniprotkb:UNQ221/PRO247(orf name)	psi-mi:lrc8a_human(display_long)|uniprotkb:LRRC8A(gene name)|psi-mi:LRRC8A(display_short)|uniprotkb:KIAA1437(gene name synonym)|uniprotkb:LRRC8(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 8A(gene name synonym)|uniprotkb:SWELL1(gene name synonym)|uniprotkb:Swelling protein 1(gene name synonym)|uniprotkb:UNQ221/PRO247(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Voss et al. (2014)	pubmed:24790029|doi:"https://doi.org/10.1126/science.1252826"|imex:IM-24117	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104690|imex:IM-24117-10|dip:DIP-198638E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120716.1|refseq:NP_001120717.1|refseq:NP_062540.2|refseq:XP_005252152.1|refseq:XP_005252153.1|refseq:XP_006717249.1|refseq:XP_011517165.1|refseq:XP_011517166.1|refseq:XP_011517167.1|ensembl:ENSG00000136802(gene)|ensembl:ENST00000259324(transcript)|ensembl:ENST00000372599(transcript)|ensembl:ENST00000372600(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140360"(cyclic-GMP-AMP transmembrane transporter activity)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR032675|mint:Q8IWT6|rcsb pdb:5ZSU|rcsb pdb:6DJB|reactome:R-HSA-5223345|dip:DIP-61360N	refseq:NP_001120716.1|refseq:NP_001120717.1|refseq:NP_062540.2|refseq:XP_005252152.1|refseq:XP_005252153.1|refseq:XP_006717249.1|refseq:XP_011517165.1|refseq:XP_011517166.1|refseq:XP_011517167.1|ensembl:ENSG00000136802(gene)|ensembl:ENST00000259324(transcript)|ensembl:ENST00000372599(transcript)|ensembl:ENST00000372600(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140360"(cyclic-GMP-AMP transmembrane transporter activity)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR032675|mint:Q8IWT6|rcsb pdb:5ZSU|rcsb pdb:6DJB|reactome:R-HSA-5223345|dip:DIP-61360N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:4+VhpXqOjBfbrNagOqJ7eY/qy+s9606	rogid:4+VhpXqOjBfbrNagOqJ7eY/qy+s9606	rigid:dxDFXGVmuWpvcVchClcWDehcft0	false	green fluorescent protein tag:n-n	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8TDW0	uniprotkb:Q8IWT6	intact:EBI-6916516|ensembl:ENSP00000359483|uniprotkb:B3KXS9|uniprotkb:Q29RV6|uniprotkb:Q9H075	intact:EBI-10970086|ensembl:ENSP00000259324|ensembl:ENSP00000361680|ensembl:ENSP00000361682|uniprotkb:Q9P2B1|uniprotkb:Q8NCI0|uniprotkb:Q6UXM2	psi-mi:lrc8c_human(display_long)|uniprotkb:LRRC8C(gene name)|psi-mi:LRRC8C(display_short)|uniprotkb:AD158(gene name synonym)|uniprotkb:FAD158(gene name synonym)|uniprotkb:Factor for adipocyte differentiation 158(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 8C(gene name synonym)	psi-mi:lrc8a_human(display_long)|uniprotkb:LRRC8A(gene name)|psi-mi:LRRC8A(display_short)|uniprotkb:KIAA1437(gene name synonym)|uniprotkb:LRRC8(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 8A(gene name synonym)|uniprotkb:SWELL1(gene name synonym)|uniprotkb:Swelling protein 1(gene name synonym)|uniprotkb:UNQ221/PRO247(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Voss et al. (2014)	pubmed:24790029|doi:"https://doi.org/10.1126/science.1252826"|imex:IM-24117	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104671|imex:IM-24117-9|dip:DIP-198640E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011540584.1|refseq:XP_016857992.1|ensembl:ENSG00000171488(gene)|ensembl:ENST00000370454(transcript)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR026906|interpro:IPR032675|reactome:R-HSA-5223345|refseq:NP_115646.2|dip:DIP-61362N	refseq:NP_001120716.1|refseq:NP_001120717.1|refseq:NP_062540.2|refseq:XP_005252152.1|refseq:XP_005252153.1|refseq:XP_006717249.1|refseq:XP_011517165.1|refseq:XP_011517166.1|refseq:XP_011517167.1|ensembl:ENSG00000136802(gene)|ensembl:ENST00000259324(transcript)|ensembl:ENST00000372599(transcript)|ensembl:ENST00000372600(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140360"(cyclic-GMP-AMP transmembrane transporter activity)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR032675|mint:Q8IWT6|rcsb pdb:5ZSU|rcsb pdb:6DJB|reactome:R-HSA-5223345|dip:DIP-61360N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:NFBpNm8lOZCjVt4H1a4CW91G3rU9606	rogid:4+VhpXqOjBfbrNagOqJ7eY/qy+s9606	rigid:H0sEIKI5jPxN8zAGh+QhHOyPlCc	false	green fluorescent protein tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8TDW0	uniprotkb:Q8IWT6	intact:EBI-6916516|ensembl:ENSP00000359483|uniprotkb:B3KXS9|uniprotkb:Q29RV6|uniprotkb:Q9H075	intact:EBI-10970086|ensembl:ENSP00000259324|ensembl:ENSP00000361680|ensembl:ENSP00000361682|uniprotkb:Q9P2B1|uniprotkb:Q8NCI0|uniprotkb:Q6UXM2	psi-mi:lrc8c_human(display_long)|uniprotkb:LRRC8C(gene name)|psi-mi:LRRC8C(display_short)|uniprotkb:AD158(gene name synonym)|uniprotkb:FAD158(gene name synonym)|uniprotkb:Factor for adipocyte differentiation 158(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 8C(gene name synonym)	psi-mi:lrc8a_human(display_long)|uniprotkb:LRRC8A(gene name)|psi-mi:LRRC8A(display_short)|uniprotkb:KIAA1437(gene name synonym)|uniprotkb:LRRC8(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 8A(gene name synonym)|uniprotkb:SWELL1(gene name synonym)|uniprotkb:Swelling protein 1(gene name synonym)|uniprotkb:UNQ221/PRO247(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Voss et al. (2014)	pubmed:24790029|doi:"https://doi.org/10.1126/science.1252826"|imex:IM-24117	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104650|imex:IM-24117-8|dip:DIP-198640E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011540584.1|refseq:XP_016857992.1|ensembl:ENSG00000171488(gene)|ensembl:ENST00000370454(transcript)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR026906|interpro:IPR032675|reactome:R-HSA-5223345|refseq:NP_115646.2|dip:DIP-61362N	refseq:NP_001120716.1|refseq:NP_001120717.1|refseq:NP_062540.2|refseq:XP_005252152.1|refseq:XP_005252153.1|refseq:XP_006717249.1|refseq:XP_011517165.1|refseq:XP_011517166.1|refseq:XP_011517167.1|ensembl:ENSG00000136802(gene)|ensembl:ENST00000259324(transcript)|ensembl:ENST00000372599(transcript)|ensembl:ENST00000372600(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140360"(cyclic-GMP-AMP transmembrane transporter activity)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR032675|mint:Q8IWT6|rcsb pdb:5ZSU|rcsb pdb:6DJB|reactome:R-HSA-5223345|dip:DIP-61360N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:NFBpNm8lOZCjVt4H1a4CW91G3rU9606	rogid:4+VhpXqOjBfbrNagOqJ7eY/qy+s9606	rigid:H0sEIKI5jPxN8zAGh+QhHOyPlCc	false	green fluorescent protein tag:n-n	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q6NSJ5	uniprotkb:Q8IWT6	intact:EBI-8647013|ensembl:ENSP00000306524|ensembl:ENSP00000479953|uniprotkb:Q7L236|uniprotkb:Q8N3B0|uniprotkb:Q2YDY3|uniprotkb:Q9H5H8|uniprotkb:B3KR78|intact:MINT-8163602	intact:EBI-10970086|ensembl:ENSP00000259324|ensembl:ENSP00000361680|ensembl:ENSP00000361682|uniprotkb:Q9P2B1|uniprotkb:Q8NCI0|uniprotkb:Q6UXM2	psi-mi:lrc8e_human(display_long)|uniprotkb:LRRC8E(gene name)|psi-mi:LRRC8E(display_short)|uniprotkb:Leucine-rich repeat-containing protein 8E(gene name synonym)	psi-mi:lrc8a_human(display_long)|uniprotkb:LRRC8A(gene name)|psi-mi:LRRC8A(display_short)|uniprotkb:KIAA1437(gene name synonym)|uniprotkb:LRRC8(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 8A(gene name synonym)|uniprotkb:SWELL1(gene name synonym)|uniprotkb:Swelling protein 1(gene name synonym)|uniprotkb:UNQ221/PRO247(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Voss et al. (2014)	pubmed:24790029|doi:"https://doi.org/10.1126/science.1252826"|imex:IM-24117	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16104711|imex:IM-24117-11|dip:DIP-198637E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171017(gene)|ensembl:ENST00000306708(transcript)|ensembl:ENST00000618098(transcript)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034702"(ion channel complex)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|reactome:R-HSA-5223345|interpro:IPR032675|refseq:XP_011526621.1|refseq:NP_001255213.1|refseq:NP_079337.2|refseq:NP_001255214.1|dip:DIP-61363N	refseq:NP_001120716.1|refseq:NP_001120717.1|refseq:NP_062540.2|refseq:XP_005252152.1|refseq:XP_005252153.1|refseq:XP_006717249.1|refseq:XP_011517165.1|refseq:XP_011517166.1|refseq:XP_011517167.1|ensembl:ENSG00000136802(gene)|ensembl:ENST00000259324(transcript)|ensembl:ENST00000372599(transcript)|ensembl:ENST00000372600(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140360"(cyclic-GMP-AMP transmembrane transporter activity)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR032675|mint:Q8IWT6|rcsb pdb:5ZSU|rcsb pdb:6DJB|reactome:R-HSA-5223345|dip:DIP-61360N	psi-mi:"MI:0465"(dip)	comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/08	2017/08/10	rogid:pQHkswfwifVqchBKu1+iMkt+0qo9606	rogid:4+VhpXqOjBfbrNagOqJ7eY/qy+s9606	rigid:Ia2FNocXcf0dlq/KOYA/enpk2Hc	false	green fluorescent protein tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)