#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q99PV5 uniprotkb:Q3TQ03 intact:EBI-6143801|ensembl:ENSMUSP00000032386 intact:EBI-16101489|ensembl:ENSMUSP00000049308|ensembl:ENSMUSP00000124943|uniprotkb:Q3U1B8 psi-mi:bhe41_mouse(display_long)|uniprotkb:Bhlhe41(gene name)|psi-mi:Bhlhe41(display_short)|uniprotkb:Bhlhb3(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 3(gene name synonym)|uniprotkb:Dec2(gene name synonym)|uniprotkb:Differentially expressed in chondrocytes protein 2(gene name synonym) psi-mi:ciart_mouse(display_long)|uniprotkb:Ciart(gene name)|psi-mi:Ciart(display_short)|uniprotkb:Gm129(gene name synonym)|uniprotkb:ChIP-derived repressor of network oscillator(gene name synonym)|uniprotkb:Computationally highlighted repressor of the network oscillator(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goriki et al. (2014) pubmed:24736997|doi:10.1371/journal.pbio.1001839|imex:IM-22677 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16101516|imex:IM-22677-1|dip:DIP-196480E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001258697.1|refseq:NP_077789.1|dip:DIP-57696N|ensembl:ENSMUSG00000030256(gene)|ensembl:ENSMUST00000032386(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043426"(MRF binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:Q99PV5 ensembl:ENSMUSG00000038550(gene)|ensembl:ENSMUST00000036418(transcript)|ensembl:ENSMUST00000159739(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|interpro:IPR031373|refseq:NP_001028474.1|refseq:XP_006501437.1|refseq:XP_006501438.1|dip:DIP-60818N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/07 2017/08/10 rogid:VvdWfxegh8slzgcei4PIZ4VsOXU10090 rogid:6Eg6HOpauJOn1zN0shzZywhHwWI10090 rigid:NFg0/vy32eE08kmANzonpzcVLGk false flag tag:c-c ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9R194 uniprotkb:Q3TQ03 intact:EBI-1266619|uniprotkb:O08706|uniprotkb:Q6A024|ensembl:ENSMUSP00000088047|ensembl:ENSMUSP00000106909 intact:EBI-16101489|ensembl:ENSMUSP00000049308|ensembl:ENSMUSP00000124943|uniprotkb:Q3U1B8 psi-mi:cry2_mouse(display_long)|uniprotkb:Cry2(gene name)|psi-mi:Cry2(display_short)|uniprotkb:Kiaa0658(gene name synonym) psi-mi:ciart_mouse(display_long)|uniprotkb:Ciart(gene name)|psi-mi:Ciart(display_short)|uniprotkb:Gm129(gene name synonym)|uniprotkb:ChIP-derived repressor of network oscillator(gene name synonym)|uniprotkb:Computationally highlighted repressor of the network oscillator(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goriki et al. (2014) pubmed:24736997|doi:10.1371/journal.pbio.1001839|imex:IM-22677 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16101554|imex:IM-22677-3|dip:DIP-196479E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034093.1|refseq:XP_017170770.1|dip:DIP-38517N|ensembl:ENSMUSG00000068742(gene)|ensembl:ENSMUST00000090559(transcript)|ensembl:ENSMUST00000111278(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071949"(FAD binding)|go:"GO:2000118"(regulation of sodium-dependent phosphate transport)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:Q9R194|rcsb pdb:4I6E|rcsb pdb:4I6G|rcsb pdb:4I6J|rcsb pdb:4MLP|rcsb pdb:4U8H|rcsb pdb:6KX8|rcsb pdb:7D0N|rcsb pdb:7EJ9 ensembl:ENSMUSG00000038550(gene)|ensembl:ENSMUST00000036418(transcript)|ensembl:ENSMUST00000159739(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|interpro:IPR031373|refseq:NP_001028474.1|refseq:XP_006501437.1|refseq:XP_006501438.1|dip:DIP-60818N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/07 2017/08/10 rogid:00SKIwCL33BKjjyPSsxZUR5Sjbs10090 rogid:6Eg6HOpauJOn1zN0shzZywhHwWI10090 rigid:MI5tXR8uw8nkJl5VHqKz7MsGXhg false flag tag:c-c ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3TQ03 uniprotkb:P06537-1 intact:EBI-16101489|ensembl:ENSMUSP00000049308|ensembl:ENSMUSP00000124943|uniprotkb:Q3U1B8 intact:EBI-15959147 psi-mi:ciart_mouse(display_long)|uniprotkb:Ciart(gene name)|psi-mi:Ciart(display_short)|uniprotkb:Gm129(gene name synonym)|uniprotkb:ChIP-derived repressor of network oscillator(gene name synonym)|uniprotkb:Computationally highlighted repressor of the network oscillator(gene name synonym) psi-mi:p06537-1(display_long)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym)|uniprotkb:Grl1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:1-A(isoform synonym)|uniprotkb:Alpha(isoform synonym)|uniprotkb:GR form A(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goriki et al. (2014) pubmed:24736997|doi:10.1371/journal.pbio.1001839|imex:IM-22677 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16101537|imex:IM-22677-2|dip:DIP-196475E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038550(gene)|ensembl:ENSMUST00000036418(transcript)|ensembl:ENSMUST00000159739(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|interpro:IPR031373|refseq:NP_001028474.1|refseq:XP_006501437.1|refseq:XP_006501438.1|dip:DIP-60818N intact:EBI-492753(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2021/11/30 rogid:6Eg6HOpauJOn1zN0shzZywhHwWI10090 rogid:BGeJbz2zNEPZBn4cdswdbgRBif410090 rigid:j+xW0KgqU/jo+3NVQxafDF3VC2A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O09106 uniprotkb:Q3TQ03 intact:EBI-301912|uniprotkb:P97476|ensembl:ENSMUSP00000099657 intact:EBI-16101489|ensembl:ENSMUSP00000049308|ensembl:ENSMUSP00000124943|uniprotkb:Q3U1B8 psi-mi:hdac1_mouse(display_long)|uniprotkb:Hdac1(gene name)|psi-mi:Hdac1(display_short) psi-mi:ciart_mouse(display_long)|uniprotkb:Ciart(gene name)|psi-mi:Ciart(display_short)|uniprotkb:Gm129(gene name synonym)|uniprotkb:ChIP-derived repressor of network oscillator(gene name synonym)|uniprotkb:Computationally highlighted repressor of the network oscillator(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goriki et al. (2014) pubmed:24736997|doi:10.1371/journal.pbio.1001839|imex:IM-22677 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16101575|imex:IM-22677-4|dip:DIP-196477E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-31499N|ensembl:ENSMUSG00000028800(gene)|ensembl:ENSMUST00000102597(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_032254.1|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:O09106|reactome:R-MMU-1538133|reactome:R-MMU-201722|reactome:R-MMU-2173795|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-3769402|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8936459|reactome:R-MMU-8943724|reactome:R-MMU-9018519|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0001046"(core promoter sequence-specific DNA binding) ensembl:ENSMUSG00000038550(gene)|ensembl:ENSMUST00000036418(transcript)|ensembl:ENSMUST00000159739(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|interpro:IPR031373|refseq:NP_001028474.1|refseq:XP_006501437.1|refseq:XP_006501438.1|dip:DIP-60818N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/07 2017/08/10 rogid:P7QV++FiMiNcabUkswbnNhGVU3410090 rogid:6Eg6HOpauJOn1zN0shzZywhHwWI10090 rigid:uHn9IqRudso3E0lnzYzIjiXAbZc false flag tag:c-c ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54943 uniprotkb:Q3TQ03 intact:EBI-1266779|uniprotkb:O54954 intact:EBI-16101489|ensembl:ENSMUSP00000049308|ensembl:ENSMUSP00000124943|uniprotkb:Q3U1B8 psi-mi:per2_mouse(display_long)|uniprotkb:Per2(gene name)|psi-mi:Per2(display_short)|uniprotkb:Circadian clock protein PERIOD 2(gene name synonym) psi-mi:ciart_mouse(display_long)|uniprotkb:Ciart(gene name)|psi-mi:Ciart(display_short)|uniprotkb:Gm129(gene name synonym)|uniprotkb:ChIP-derived repressor of network oscillator(gene name synonym)|uniprotkb:Computationally highlighted repressor of the network oscillator(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goriki et al. (2014) pubmed:24736997|doi:10.1371/journal.pbio.1001839|imex:IM-22677 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16101596|imex:IM-22677-5|dip:DIP-196478E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035196.2|mint:O54943|dip:DIP-38518N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051946"(regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0060567"(negative regulation of DNA-templated transcription, termination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|rcsb pdb:3GDI|rcsb pdb:4CT0|rcsb pdb:4U8H ensembl:ENSMUSG00000038550(gene)|ensembl:ENSMUST00000036418(transcript)|ensembl:ENSMUST00000159739(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|interpro:IPR031373|refseq:NP_001028474.1|refseq:XP_006501437.1|refseq:XP_006501438.1|dip:DIP-60818N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/07 2017/08/10 rogid:bA+e5kx1ZkqfPRHn3TDAuhmqAw410090 rogid:6Eg6HOpauJOn1zN0shzZywhHwWI10090 rigid:PK4ARp5GBWjqxC8JNEXk3h/k2nk false myc tag:c-c flag tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WTL8 uniprotkb:Q3TQ03 intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9 intact:EBI-16101489|ensembl:ENSMUSP00000049308|ensembl:ENSMUSP00000124943|uniprotkb:Q3U1B8 psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym) psi-mi:ciart_mouse(display_long)|uniprotkb:Ciart(gene name)|psi-mi:Ciart(display_short)|uniprotkb:Gm129(gene name synonym)|uniprotkb:ChIP-derived repressor of network oscillator(gene name synonym)|uniprotkb:Computationally highlighted repressor of the network oscillator(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goriki et al. (2014) pubmed:24736997|doi:10.1371/journal.pbio.1001839|imex:IM-22677 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16101617|imex:IM-22677-6|dip:DIP-196476E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8 ensembl:ENSMUSG00000038550(gene)|ensembl:ENSMUST00000036418(transcript)|ensembl:ENSMUST00000159739(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|interpro:IPR031373|refseq:NP_001028474.1|refseq:XP_006501437.1|refseq:XP_006501438.1|dip:DIP-60818N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090 rogid:6Eg6HOpauJOn1zN0shzZywhHwWI10090 rigid:tnpnltvXh1Tgnx3RQRmpKn1TOms false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9WTL8 uniprotkb:Q3TQ03 intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9 intact:EBI-16101489|ensembl:ENSMUSP00000049308|ensembl:ENSMUSP00000124943|uniprotkb:Q3U1B8 psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym) psi-mi:ciart_mouse(display_long)|uniprotkb:Ciart(gene name)|psi-mi:Ciart(display_short)|uniprotkb:Gm129(gene name synonym)|uniprotkb:ChIP-derived repressor of network oscillator(gene name synonym)|uniprotkb:Computationally highlighted repressor of the network oscillator(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goriki et al. (2014) pubmed:24736997|doi:10.1371/journal.pbio.1001839|imex:IM-22677 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16101634|imex:IM-22677-7|dip:DIP-196476E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8 ensembl:ENSMUSG00000038550(gene)|ensembl:ENSMUST00000036418(transcript)|ensembl:ENSMUST00000159739(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|interpro:IPR031373|refseq:NP_001028474.1|refseq:XP_006501437.1|refseq:XP_006501438.1|dip:DIP-60818N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/07 2017/08/10 rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090 rogid:6Eg6HOpauJOn1zN0shzZywhHwWI10090 rigid:tnpnltvXh1Tgnx3RQRmpKn1TOms false ha tag:c-c flag tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99PV5 uniprotkb:Q3TQ03 intact:EBI-6143801|ensembl:ENSMUSP00000032386 intact:EBI-16101489|ensembl:ENSMUSP00000049308|ensembl:ENSMUSP00000124943|uniprotkb:Q3U1B8 psi-mi:bhe41_mouse(display_long)|uniprotkb:Bhlhe41(gene name)|psi-mi:Bhlhe41(display_short)|uniprotkb:Bhlhb3(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 3(gene name synonym)|uniprotkb:Dec2(gene name synonym)|uniprotkb:Differentially expressed in chondrocytes protein 2(gene name synonym) psi-mi:ciart_mouse(display_long)|uniprotkb:Ciart(gene name)|psi-mi:Ciart(display_short)|uniprotkb:Gm129(gene name synonym)|uniprotkb:ChIP-derived repressor of network oscillator(gene name synonym)|uniprotkb:Computationally highlighted repressor of the network oscillator(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goriki et al. (2014) pubmed:24736997|doi:10.1371/journal.pbio.1001839|imex:IM-22677 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16101655|imex:IM-22677-8|dip:DIP-196480E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001258697.1|refseq:NP_077789.1|dip:DIP-57696N|ensembl:ENSMUSG00000030256(gene)|ensembl:ENSMUST00000032386(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043426"(MRF binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:Q99PV5 ensembl:ENSMUSG00000038550(gene)|ensembl:ENSMUST00000036418(transcript)|ensembl:ENSMUST00000159739(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|interpro:IPR031373|refseq:NP_001028474.1|refseq:XP_006501437.1|refseq:XP_006501438.1|dip:DIP-60818N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/07 2017/08/10 rogid:VvdWfxegh8slzgcei4PIZ4VsOXU10090 rogid:6Eg6HOpauJOn1zN0shzZywhHwWI10090 rigid:NFg0/vy32eE08kmANzonpzcVLGk false flag tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9R194 uniprotkb:Q3TQ03 intact:EBI-1266619|uniprotkb:O08706|uniprotkb:Q6A024|ensembl:ENSMUSP00000088047|ensembl:ENSMUSP00000106909 intact:EBI-16101489|ensembl:ENSMUSP00000049308|ensembl:ENSMUSP00000124943|uniprotkb:Q3U1B8 psi-mi:cry2_mouse(display_long)|uniprotkb:Cry2(gene name)|psi-mi:Cry2(display_short)|uniprotkb:Kiaa0658(gene name synonym) psi-mi:ciart_mouse(display_long)|uniprotkb:Ciart(gene name)|psi-mi:Ciart(display_short)|uniprotkb:Gm129(gene name synonym)|uniprotkb:ChIP-derived repressor of network oscillator(gene name synonym)|uniprotkb:Computationally highlighted repressor of the network oscillator(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goriki et al. (2014) pubmed:24736997|doi:10.1371/journal.pbio.1001839|imex:IM-22677 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16101718|imex:IM-22677-11|dip:DIP-196479E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034093.1|refseq:XP_017170770.1|dip:DIP-38517N|ensembl:ENSMUSG00000068742(gene)|ensembl:ENSMUST00000090559(transcript)|ensembl:ENSMUST00000111278(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071949"(FAD binding)|go:"GO:2000118"(regulation of sodium-dependent phosphate transport)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:Q9R194|rcsb pdb:4I6E|rcsb pdb:4I6G|rcsb pdb:4I6J|rcsb pdb:4MLP|rcsb pdb:4U8H|rcsb pdb:6KX8|rcsb pdb:7D0N|rcsb pdb:7EJ9 ensembl:ENSMUSG00000038550(gene)|ensembl:ENSMUST00000036418(transcript)|ensembl:ENSMUST00000159739(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|interpro:IPR031373|refseq:NP_001028474.1|refseq:XP_006501437.1|refseq:XP_006501438.1|dip:DIP-60818N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/07 2017/08/10 rogid:00SKIwCL33BKjjyPSsxZUR5Sjbs10090 rogid:6Eg6HOpauJOn1zN0shzZywhHwWI10090 rigid:MI5tXR8uw8nkJl5VHqKz7MsGXhg false flag tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O09106 uniprotkb:Q3TQ03 intact:EBI-301912|uniprotkb:P97476|ensembl:ENSMUSP00000099657 intact:EBI-16101489|ensembl:ENSMUSP00000049308|ensembl:ENSMUSP00000124943|uniprotkb:Q3U1B8 psi-mi:hdac1_mouse(display_long)|uniprotkb:Hdac1(gene name)|psi-mi:Hdac1(display_short) psi-mi:ciart_mouse(display_long)|uniprotkb:Ciart(gene name)|psi-mi:Ciart(display_short)|uniprotkb:Gm129(gene name synonym)|uniprotkb:ChIP-derived repressor of network oscillator(gene name synonym)|uniprotkb:Computationally highlighted repressor of the network oscillator(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goriki et al. (2014) pubmed:24736997|doi:10.1371/journal.pbio.1001839|imex:IM-22677 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16101697|imex:IM-22677-10|dip:DIP-196477E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-31499N|ensembl:ENSMUSG00000028800(gene)|ensembl:ENSMUST00000102597(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_032254.1|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:O09106|reactome:R-MMU-1538133|reactome:R-MMU-201722|reactome:R-MMU-2173795|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-3769402|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8936459|reactome:R-MMU-8943724|reactome:R-MMU-9018519|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0001046"(core promoter sequence-specific DNA binding) ensembl:ENSMUSG00000038550(gene)|ensembl:ENSMUST00000036418(transcript)|ensembl:ENSMUST00000159739(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|interpro:IPR031373|refseq:NP_001028474.1|refseq:XP_006501437.1|refseq:XP_006501438.1|dip:DIP-60818N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/07 2017/08/10 rogid:P7QV++FiMiNcabUkswbnNhGVU3410090 rogid:6Eg6HOpauJOn1zN0shzZywhHwWI10090 rigid:uHn9IqRudso3E0lnzYzIjiXAbZc false flag tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9WTL8 uniprotkb:Q3TQ03 intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9 intact:EBI-16101489|ensembl:ENSMUSP00000049308|ensembl:ENSMUSP00000124943|uniprotkb:Q3U1B8 psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym) psi-mi:ciart_mouse(display_long)|uniprotkb:Ciart(gene name)|psi-mi:Ciart(display_short)|uniprotkb:Gm129(gene name synonym)|uniprotkb:ChIP-derived repressor of network oscillator(gene name synonym)|uniprotkb:Computationally highlighted repressor of the network oscillator(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goriki et al. (2014) pubmed:24736997|doi:10.1371/journal.pbio.1001839|imex:IM-22677 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16101676|imex:IM-22677-9|dip:DIP-196476E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8 ensembl:ENSMUSG00000038550(gene)|ensembl:ENSMUST00000036418(transcript)|ensembl:ENSMUST00000159739(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|interpro:IPR031373|refseq:NP_001028474.1|refseq:XP_006501437.1|refseq:XP_006501438.1|dip:DIP-60818N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/07 2017/08/10 rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090 rogid:6Eg6HOpauJOn1zN0shzZywhHwWI10090 rigid:tnpnltvXh1Tgnx3RQRmpKn1TOms false ha tag:c-c flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O54943 uniprotkb:Q3TQ03 intact:EBI-1266779|uniprotkb:O54954 intact:EBI-16101489|ensembl:ENSMUSP00000049308|ensembl:ENSMUSP00000124943|uniprotkb:Q3U1B8 psi-mi:per2_mouse(display_long)|uniprotkb:Per2(gene name)|psi-mi:Per2(display_short)|uniprotkb:Circadian clock protein PERIOD 2(gene name synonym) psi-mi:ciart_mouse(display_long)|uniprotkb:Ciart(gene name)|psi-mi:Ciart(display_short)|uniprotkb:Gm129(gene name synonym)|uniprotkb:ChIP-derived repressor of network oscillator(gene name synonym)|uniprotkb:Computationally highlighted repressor of the network oscillator(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goriki et al. (2014) pubmed:24736997|doi:10.1371/journal.pbio.1001839|imex:IM-22677 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16101739|imex:IM-22677-12|dip:DIP-196478E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035196.2|mint:O54943|dip:DIP-38518N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051946"(regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0060567"(negative regulation of DNA-templated transcription, termination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|rcsb pdb:3GDI|rcsb pdb:4CT0|rcsb pdb:4U8H ensembl:ENSMUSG00000038550(gene)|ensembl:ENSMUST00000036418(transcript)|ensembl:ENSMUST00000159739(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|interpro:IPR031373|refseq:NP_001028474.1|refseq:XP_006501437.1|refseq:XP_006501438.1|dip:DIP-60818N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/07 2017/08/10 rogid:bA+e5kx1ZkqfPRHn3TDAuhmqAw410090 rogid:6Eg6HOpauJOn1zN0shzZywhHwWI10090 rigid:PK4ARp5GBWjqxC8JNEXk3h/k2nk false myc tag:c-c flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)