#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P06971 uniprotkb:Q9X2V7 intact:EBI-1116714|uniprotkb:P71280|uniprotkb:P75665|ensemblbacteria:AAC73261|ensemblbacteria:BAB96726 intact:EBI-16100378 psi-mi:fhua_ecoli(display_long)|uniprotkb:JW0146(locus name)|uniprotkb:fhuA(gene name)|psi-mi:fhuA(display_short)|uniprotkb:tonA(gene name synonym)|uniprotkb:b0150(locus name)|uniprotkb:Ferric hydroxamate uptake(gene name synonym)|uniprotkb:Ferric hydroxamate receptor(gene name synonym)|uniprotkb:Ferrichrome-iron receptor(gene name synonym) psi-mi:mcja_ecolx(display_long)|uniprotkb:mcjA(gene name)|psi-mi:mcjA(display_short)|uniprotkb:Class II lasso peptide(gene name synonym)|uniprotkb:Ribosomally synthesized and post-translationally modified peptide(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Mathavan et al. (2014) pubmed:24705590|doi:10.1038/nchembio.1499|imex:IM-22710 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:562(ecolx)|taxid:562(Escherichia coli) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16100395|imex:IM-22710-1|dip:DIP-196604E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000124438.1|refseq:NP_414692.1|interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039423|rcsb pdb:1BY3|rcsb pdb:1BY5|rcsb pdb:1FCP|rcsb pdb:1FI1|rcsb pdb:1QFF|rcsb pdb:1QFG|rcsb pdb:1QJQ|rcsb pdb:1QKC|rcsb pdb:2FCP|rcsb pdb:2GRX|rcsb pdb:4CU4|ensemblbacteria:AAC73261(transcript)|ensemblbacteria:b0150(gene)|ensemblbacteria:BAB96726(gene)|ensemblbacteria:BAB96726(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015344"(siderophore uptake transmembrane transporter activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0046790"(virion binding)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR010917(TonB-dependent receptor, conserved site)|dip:DIP-9602N go:"GO:0005576"(extracellular region)|go:"GO:0019835"(cytolysis)|go:"GO:0042742"(defense response to bacterium)|rcsb pdb:1PP5|rcsb pdb:1Q71|rcsb pdb:1S7P|rcsb pdb:2MMT|rcsb pdb:2MMW|rcsb pdb:4CU4|rcsb pdb:6N60|refseq:WP_001513516.1|refseq:YP_009071192.1|dip:DIP-60856N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:YuhazS970KcEsyZqYsiK4AAwsqI83333 rogid:LvobqGOSA9f4ZF6j1u5sPeLY0dU562 rigid:FaiqKH/IO0JG/JnWKa2WHZyLeTo false sufficient binding region:53-747 sufficient binding region:38-58 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06971 uniprotkb:Q9X2V7 intact:EBI-1116714|uniprotkb:P71280|uniprotkb:P75665|ensemblbacteria:AAC73261|ensemblbacteria:BAB96726 intact:EBI-16100378 psi-mi:fhua_ecoli(display_long)|uniprotkb:JW0146(locus name)|uniprotkb:fhuA(gene name)|psi-mi:fhuA(display_short)|uniprotkb:tonA(gene name synonym)|uniprotkb:b0150(locus name)|uniprotkb:Ferric hydroxamate uptake(gene name synonym)|uniprotkb:Ferric hydroxamate receptor(gene name synonym)|uniprotkb:Ferrichrome-iron receptor(gene name synonym) psi-mi:mcja_ecolx(display_long)|uniprotkb:mcjA(gene name)|psi-mi:mcjA(display_short)|uniprotkb:Class II lasso peptide(gene name synonym)|uniprotkb:Ribosomally synthesized and post-translationally modified peptide(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Mathavan et al. (2014) pubmed:24705590|doi:10.1038/nchembio.1499|imex:IM-22710 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:562(ecolx)|taxid:562(Escherichia coli) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16100416|imex:IM-22710-2|dip:DIP-196604E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000124438.1|refseq:NP_414692.1|interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039423|rcsb pdb:1BY3|rcsb pdb:1BY5|rcsb pdb:1FCP|rcsb pdb:1FI1|rcsb pdb:1QFF|rcsb pdb:1QFG|rcsb pdb:1QJQ|rcsb pdb:1QKC|rcsb pdb:2FCP|rcsb pdb:2GRX|rcsb pdb:4CU4|ensemblbacteria:AAC73261(transcript)|ensemblbacteria:b0150(gene)|ensemblbacteria:BAB96726(gene)|ensemblbacteria:BAB96726(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015344"(siderophore uptake transmembrane transporter activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0046790"(virion binding)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR010917(TonB-dependent receptor, conserved site)|dip:DIP-9602N go:"GO:0005576"(extracellular region)|go:"GO:0019835"(cytolysis)|go:"GO:0042742"(defense response to bacterium)|rcsb pdb:1PP5|rcsb pdb:1Q71|rcsb pdb:1S7P|rcsb pdb:2MMT|rcsb pdb:2MMW|rcsb pdb:4CU4|rcsb pdb:6N60|refseq:WP_001513516.1|refseq:YP_009071192.1|dip:DIP-60856N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:YuhazS970KcEsyZqYsiK4AAwsqI83333 rogid:LvobqGOSA9f4ZF6j1u5sPeLY0dU562 rigid:FaiqKH/IO0JG/JnWKa2WHZyLeTo false sufficient binding region:53-747 sufficient binding region:38-58|mutation decreasing interaction strength:42-42 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)