#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UHB9 uniprotkb:Q9UHB9 intact:EBI-1048560|uniprotkb:Q8NCJ4|uniprotkb:Q8WUK2|uniprotkb:B3KUU5|uniprotkb:B3KWY7|uniprotkb:G3V1U4|ensembl:ENSP00000312066 intact:EBI-1048560|uniprotkb:Q8NCJ4|uniprotkb:Q8WUK2|uniprotkb:B3KUU5|uniprotkb:B3KWY7|uniprotkb:G3V1U4|ensembl:ENSP00000312066 psi-mi:srp68_human(display_long)|uniprotkb:SRP68(gene name)|psi-mi:SRP68(display_short)|uniprotkb:Signal recognition particle 68 kDa protein(gene name synonym) psi-mi:srp68_human(display_long)|uniprotkb:SRP68(gene name)|psi-mi:SRP68(display_short)|uniprotkb:Signal recognition particle 68 kDa protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Grotwinkel et al. (2014) pubmed:24700861|doi:"https://doi.org/10.1126/science.1249094"|imex:IM-24118 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16099178|imex:IM-24118-1|dip:DIP-198643E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001247431.1|refseq:NP_001247432.1|refseq:NP_055045.2|interpro:IPR026258|interpro:IPR034652|interpro:IPR038253|mint:Q9UHB9|rcsb pdb:4P3E|rcsb pdb:4P3F|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:7NFX|reactome:R-HSA-1799339|ensembl:ENSG00000167881(gene)|ensembl:ENST00000307877(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0042493"|go:"GO:0048500"(signal recognition particle)|dip:DIP-50905N refseq:NP_001247431.1|refseq:NP_001247432.1|refseq:NP_055045.2|interpro:IPR026258|interpro:IPR034652|interpro:IPR038253|mint:Q9UHB9|rcsb pdb:4P3E|rcsb pdb:4P3F|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:7NFX|reactome:R-HSA-1799339|ensembl:ENSG00000167881(gene)|ensembl:ENST00000307877(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0042493"|go:"GO:0048500"(signal recognition particle)|dip:DIP-50905N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:8WwEMUV+QzJGJ6G7xufvSibYTSY9606 rogid:8WwEMUV+QzJGJ6G7xufvSibYTSY9606 rigid:xKXOsRxbe3XiRxwU5SWVp4x4IK8 false sufficient binding region:47-254 sufficient binding region:47-254 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UHB9 uniprotkb:P09132 intact:EBI-1048560|uniprotkb:Q8NCJ4|uniprotkb:Q8WUK2|uniprotkb:B3KUU5|uniprotkb:B3KWY7|uniprotkb:G3V1U4|ensembl:ENSP00000312066 intact:EBI-2680090|uniprotkb:B2R4E9|uniprotkb:Q96FG6|uniprotkb:Q05D77|uniprotkb:D6RCQ5|ensembl:ENSP00000424870 psi-mi:srp68_human(display_long)|uniprotkb:SRP68(gene name)|psi-mi:SRP68(display_short)|uniprotkb:Signal recognition particle 68 kDa protein(gene name synonym) psi-mi:srp19_human(display_long)|uniprotkb:SRP19(gene name)|psi-mi:SRP19(display_short) psi-mi:"MI:0071"(molecular sieving) Grotwinkel et al. (2014) pubmed:24700861|doi:"https://doi.org/10.1126/science.1249094"|imex:IM-24118 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16099196|imex:IM-24118-2|dip:DIP-198642E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001247431.1|refseq:NP_001247432.1|refseq:NP_055045.2|interpro:IPR026258|interpro:IPR034652|interpro:IPR038253|mint:Q9UHB9|rcsb pdb:4P3E|rcsb pdb:4P3F|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:7NFX|reactome:R-HSA-1799339|ensembl:ENSG00000167881(gene)|ensembl:ENST00000307877(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0042493"|go:"GO:0048500"(signal recognition particle)|dip:DIP-50905N refseq:NP_001191123.1|refseq:NP_003126.1|refseq:NP_001191122.1|refseq:NP_001191125.1|ensembl:ENSG00000153037(gene)|ensembl:ENST00000505459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006617"(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:"GO:0008312"(7S RNA binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR002778(Signal recognition particle, SRP19 subunit)|interpro:IPR036521|mint:P09132|rcsb pdb:1JID|rcsb pdb:1MFQ|rcsb pdb:1RY1|rcsb pdb:2J37|rcsb pdb:3KTV|rcsb pdb:4P3E|rcsb pdb:5M73|rcsb pdb:7NFX|reactome:R-HSA-1799339|dip:DIP-41412N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:8WwEMUV+QzJGJ6G7xufvSibYTSY9606 rogid:yIFmf1q6m2wQt3eaiCc1dlIQXn89606 rigid:L/0wJjPJ7AD12wbKLibAjd2VBgY false sufficient binding region:47-254 sufficient binding region:1-120 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G0S5V2 uniprotkb:G0S5V2 intact:EBI-16099218|ensemblfungi:EGS21514 intact:EBI-16099218|ensemblfungi:EGS21514 psi-mi:g0s5v2_chatd(display_long)|uniprotkb:CTHT_0033730(orf name) psi-mi:g0s5v2_chatd(display_long)|uniprotkb:CTHT_0033730(orf name) psi-mi:"MI:0114"(x-ray crystallography) Grotwinkel et al. (2014) pubmed:24700861|doi:"https://doi.org/10.1126/science.1249094"|imex:IM-24118 taxid:759272(chatd)|taxid:759272("Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)") taxid:759272(chatd)|taxid:759272("Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16099233|imex:IM-24118-3|dip:DIP-198644E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:CTHT_0033730(gene)|ensemblfungi:EGS21514(transcript)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|interpro:IPR026258|interpro:IPR034652|interpro:IPR038253|rcsb pdb:4P3G|refseq:XP_006693810.1|dip:DIP-61364N ensemblfungi:CTHT_0033730(gene)|ensemblfungi:EGS21514(transcript)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|interpro:IPR026258|interpro:IPR034652|interpro:IPR038253|rcsb pdb:4P3G|refseq:XP_006693810.1|dip:DIP-61364N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:cceP+QQyFaEP4dl8o4I6Mf6Kzog759272 rogid:cceP+QQyFaEP4dl8o4I6Mf6Kzog759272 rigid:3yc7FdeeHJoPxJTR29XRyxwc2aw false sufficient binding region:1-217 sufficient binding region:1-217 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UHB9 uniprotkb:P09132 intact:EBI-1048560|uniprotkb:Q8NCJ4|uniprotkb:Q8WUK2|uniprotkb:B3KUU5|uniprotkb:B3KWY7|uniprotkb:G3V1U4|ensembl:ENSP00000312066 intact:EBI-2680090|uniprotkb:B2R4E9|uniprotkb:Q96FG6|uniprotkb:Q05D77|uniprotkb:D6RCQ5|ensembl:ENSP00000424870 psi-mi:srp68_human(display_long)|uniprotkb:SRP68(gene name)|psi-mi:SRP68(display_short)|uniprotkb:Signal recognition particle 68 kDa protein(gene name synonym) psi-mi:srp19_human(display_long)|uniprotkb:SRP19(gene name)|psi-mi:SRP19(display_short) psi-mi:"MI:0114"(x-ray crystallography) Grotwinkel et al. (2014) pubmed:24700861|doi:"https://doi.org/10.1126/science.1249094"|imex:IM-24118 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16099252|imex:IM-24118-4|dip:DIP-198642E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001247431.1|refseq:NP_001247432.1|refseq:NP_055045.2|interpro:IPR026258|interpro:IPR034652|interpro:IPR038253|mint:Q9UHB9|rcsb pdb:4P3E|rcsb pdb:4P3F|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:7NFX|reactome:R-HSA-1799339|ensembl:ENSG00000167881(gene)|ensembl:ENST00000307877(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0042493"|go:"GO:0048500"(signal recognition particle)|dip:DIP-50905N refseq:NP_001191123.1|refseq:NP_003126.1|refseq:NP_001191122.1|refseq:NP_001191125.1|ensembl:ENSG00000153037(gene)|ensembl:ENST00000505459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006617"(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:"GO:0008312"(7S RNA binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR002778(Signal recognition particle, SRP19 subunit)|interpro:IPR036521|mint:P09132|rcsb pdb:1JID|rcsb pdb:1MFQ|rcsb pdb:1RY1|rcsb pdb:2J37|rcsb pdb:3KTV|rcsb pdb:4P3E|rcsb pdb:5M73|rcsb pdb:7NFX|reactome:R-HSA-1799339|dip:DIP-41412N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:8WwEMUV+QzJGJ6G7xufvSibYTSY9606 rogid:yIFmf1q6m2wQt3eaiCc1dlIQXn89606 rigid:L/0wJjPJ7AD12wbKLibAjd2VBgY false sufficient binding region:47-254 sufficient binding region:1-120 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)