#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P42207 uniprotkb:P40797 intact:EBI-120528|uniprotkb:Q9VRH5|uniprotkb:Q8IQ47|ensemblmetazoa:FBpp0076897 intact:EBI-171301|uniprotkb:Q0E9F5|uniprotkb:Q9V385|ensemblmetazoa:FBpp0087869|ensemblmetazoa:FBpp0087870 psi-mi:sept1_drome(display_long)|uniprotkb:DIFF6 protein homolog(gene name synonym)|uniprotkb:Protein innocent bystander(gene name synonym)|uniprotkb:CG1403(orf name)|uniprotkb:Sep1(gene name)|psi-mi:Sep1(display_short)|uniprotkb:Diff6(gene name synonym)|uniprotkb:iby(gene name synonym) psi-mi:pnut_drome(display_long)|uniprotkb:pnut(gene name)|psi-mi:pnut(display_short)|uniprotkb:CG8705(orf name) psi-mi:"MI:0096"(pull down) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16096664|imex:IM-22412-1|dip:DIP-196076E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0011710(gene)|ensemblmetazoa:FBtr0077198(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005940"(septin ring)|go:"GO:0007349"(cellularization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|refseq:NP_523430.1|flybase:FBgn0011710|dip:DIP-18454N refseq:NP_477064.1|refseq:NP_724659.1|flybase:FBgn0013726|dip:DIP-60735N|ensemblmetazoa:FBgn0013726(gene)|ensemblmetazoa:FBtr0088792(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|ensemblmetazoa:FBtr0088793(transcript)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070938"(contractile ring)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0060271"(cilium assembly) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:owbyZvFu8+uF3t60BTm9IqquTL47227 rogid:AwSNOc8ecwdqxwA6z93hfsSa7g87227 rigid:XrgHLDppFcR9n2p3mS00l5APvOw false his tag:n-n strep tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42207 uniprotkb:P54359 intact:EBI-120528|uniprotkb:Q9VRH5|uniprotkb:Q8IQ47|ensemblmetazoa:FBpp0076897 intact:EBI-188936|uniprotkb:Q24092|uniprotkb:Q9VDK8|ensemblmetazoa:FBpp0083352 psi-mi:sept1_drome(display_long)|uniprotkb:DIFF6 protein homolog(gene name synonym)|uniprotkb:Protein innocent bystander(gene name synonym)|uniprotkb:CG1403(orf name)|uniprotkb:Sep1(gene name)|psi-mi:Sep1(display_short)|uniprotkb:Diff6(gene name synonym)|uniprotkb:iby(gene name synonym) psi-mi:sept2_drome(display_long)|uniprotkb:Sep2(gene name)|psi-mi:Sep2(display_short)|uniprotkb:CG4173(orf name) psi-mi:"MI:0096"(pull down) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16096664|imex:IM-22412-1|dip:DIP-196076E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0011710(gene)|ensemblmetazoa:FBtr0077198(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005940"(septin ring)|go:"GO:0007349"(cellularization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|refseq:NP_523430.1|flybase:FBgn0011710|dip:DIP-18454N refseq:NP_524417.1|flybase:FBgn0014029|dip:DIP-20060N|ensemblmetazoa:FBgn0014029(gene)|ensemblmetazoa:FBtr0083945(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007295"(growth of a germarium-derived egg chamber)|go:"GO:0007349"(cellularization)|go:"GO:0007444"(imaginal disc development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:owbyZvFu8+uF3t60BTm9IqquTL47227 rogid:yZOoGT0rH7z1Sm3rbziG/xiMNMg7227 rigid:XrgHLDppFcR9n2p3mS00l5APvOw false his tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40797 uniprotkb:P42207 intact:EBI-171301|uniprotkb:Q0E9F5|uniprotkb:Q9V385|ensemblmetazoa:FBpp0087869|ensemblmetazoa:FBpp0087870 intact:EBI-120528|uniprotkb:Q9VRH5|uniprotkb:Q8IQ47|ensemblmetazoa:FBpp0076897 psi-mi:pnut_drome(display_long)|uniprotkb:pnut(gene name)|psi-mi:pnut(display_short)|uniprotkb:CG8705(orf name) psi-mi:sept1_drome(display_long)|uniprotkb:DIFF6 protein homolog(gene name synonym)|uniprotkb:Protein innocent bystander(gene name synonym)|uniprotkb:CG1403(orf name)|uniprotkb:Sep1(gene name)|psi-mi:Sep1(display_short)|uniprotkb:Diff6(gene name synonym)|uniprotkb:iby(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16096744|imex:IM-22412-5|dip:DIP-196076E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477064.1|refseq:NP_724659.1|flybase:FBgn0013726|dip:DIP-60735N|ensemblmetazoa:FBgn0013726(gene)|ensemblmetazoa:FBtr0088792(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|ensemblmetazoa:FBtr0088793(transcript)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070938"(contractile ring)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0060271"(cilium assembly) ensemblmetazoa:FBgn0011710(gene)|ensemblmetazoa:FBtr0077198(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005940"(septin ring)|go:"GO:0007349"(cellularization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|refseq:NP_523430.1|flybase:FBgn0011710|dip:DIP-18454N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:AwSNOc8ecwdqxwA6z93hfsSa7g87227 rogid:owbyZvFu8+uF3t60BTm9IqquTL47227 rigid:XrgHLDppFcR9n2p3mS00l5APvOw false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P40797 uniprotkb:P54359 intact:EBI-171301|uniprotkb:Q0E9F5|uniprotkb:Q9V385|ensemblmetazoa:FBpp0087869|ensemblmetazoa:FBpp0087870 intact:EBI-188936|uniprotkb:Q24092|uniprotkb:Q9VDK8|ensemblmetazoa:FBpp0083352 psi-mi:pnut_drome(display_long)|uniprotkb:pnut(gene name)|psi-mi:pnut(display_short)|uniprotkb:CG8705(orf name) psi-mi:sept2_drome(display_long)|uniprotkb:Sep2(gene name)|psi-mi:Sep2(display_short)|uniprotkb:CG4173(orf name) psi-mi:"MI:0071"(molecular sieving) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16096744|imex:IM-22412-5|dip:DIP-196076E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477064.1|refseq:NP_724659.1|flybase:FBgn0013726|dip:DIP-60735N|ensemblmetazoa:FBgn0013726(gene)|ensemblmetazoa:FBtr0088792(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|ensemblmetazoa:FBtr0088793(transcript)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070938"(contractile ring)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0060271"(cilium assembly) refseq:NP_524417.1|flybase:FBgn0014029|dip:DIP-20060N|ensemblmetazoa:FBgn0014029(gene)|ensemblmetazoa:FBtr0083945(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007295"(growth of a germarium-derived egg chamber)|go:"GO:0007349"(cellularization)|go:"GO:0007444"(imaginal disc development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:AwSNOc8ecwdqxwA6z93hfsSa7g87227 rogid:yZOoGT0rH7z1Sm3rbziG/xiMNMg7227 rigid:XrgHLDppFcR9n2p3mS00l5APvOw false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P68135 uniprotkb:P68135 intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020 intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020 psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16096726|imex:IM-22412-4|dip:DIP-87838E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986 rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986 rigid:TEHkhNh/B/C/FJ5BKfvKPB7VQNs false alexa 594 label:?-? alexa 594 label:?-? - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16181 uniprotkb:Q14141 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:"MI:0096"(pull down) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16096704|imex:IM-22412-3|dip:DIP-191030E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rigid:f+fHwMdjRNrn265IovXHjdlp26s false strep tag:c-c - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16181 uniprotkb:Q15019-1 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 intact:EBI-5279816|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172 psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:q15019-1(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:"MI:0096"(pull down) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16096704|imex:IM-22412-3|dip:DIP-191030E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|intact:EBI-741220(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rigid:f+fHwMdjRNrn265IovXHjdlp26s false strep tag:c-c his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P68135 uniprotkb:P68135 intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020 intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020 psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16096686|imex:IM-22412-2|dip:DIP-87838E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986 rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986 rigid:TEHkhNh/B/C/FJ5BKfvKPB7VQNs false alexa 488 label:?-? alexa 488 label:?-? - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P68135 uniprotkb:P68135 intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020 intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020 psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16096762|imex:IM-22412-6|dip:DIP-87838E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986 rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986 rigid:TEHkhNh/B/C/FJ5BKfvKPB7VQNs false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15019-1 uniprotkb:Q14141 intact:EBI-5279816|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 psi-mi:q15019-1(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16096858|imex:IM-22412-11|dip:DIP-191030E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|intact:EBI-741220(isoform-parent) ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rigid:f+fHwMdjRNrn265IovXHjdlp26s false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q15019-1 uniprotkb:Q16181 intact:EBI-5279816|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 psi-mi:q15019-1(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16096858|imex:IM-22412-11|dip:DIP-191030E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|intact:EBI-741220(isoform-parent) refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rigid:f+fHwMdjRNrn265IovXHjdlp26s false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P40797 uniprotkb:P54359 intact:EBI-171301|uniprotkb:Q0E9F5|uniprotkb:Q9V385|ensemblmetazoa:FBpp0087869|ensemblmetazoa:FBpp0087870 intact:EBI-188936|uniprotkb:Q24092|uniprotkb:Q9VDK8|ensemblmetazoa:FBpp0083352 psi-mi:pnut_drome(display_long)|uniprotkb:pnut(gene name)|psi-mi:pnut(display_short)|uniprotkb:CG8705(orf name) psi-mi:sept2_drome(display_long)|uniprotkb:Sep2(gene name)|psi-mi:Sep2(display_short)|uniprotkb:CG4173(orf name) psi-mi:"MI:0096"(pull down) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16096836|imex:IM-22412-10|dip:DIP-196076E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477064.1|refseq:NP_724659.1|flybase:FBgn0013726|dip:DIP-60735N|ensemblmetazoa:FBgn0013726(gene)|ensemblmetazoa:FBtr0088792(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|ensemblmetazoa:FBtr0088793(transcript)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070938"(contractile ring)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0060271"(cilium assembly) refseq:NP_524417.1|flybase:FBgn0014029|dip:DIP-20060N|ensemblmetazoa:FBgn0014029(gene)|ensemblmetazoa:FBtr0083945(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007295"(growth of a germarium-derived egg chamber)|go:"GO:0007349"(cellularization)|go:"GO:0007444"(imaginal disc development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:AwSNOc8ecwdqxwA6z93hfsSa7g87227 rogid:yZOoGT0rH7z1Sm3rbziG/xiMNMg7227 rigid:XrgHLDppFcR9n2p3mS00l5APvOw false strep tag:c-c - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40797 uniprotkb:P42207 intact:EBI-171301|uniprotkb:Q0E9F5|uniprotkb:Q9V385|ensemblmetazoa:FBpp0087869|ensemblmetazoa:FBpp0087870 intact:EBI-120528|uniprotkb:Q9VRH5|uniprotkb:Q8IQ47|ensemblmetazoa:FBpp0076897 psi-mi:pnut_drome(display_long)|uniprotkb:pnut(gene name)|psi-mi:pnut(display_short)|uniprotkb:CG8705(orf name) psi-mi:sept1_drome(display_long)|uniprotkb:DIFF6 protein homolog(gene name synonym)|uniprotkb:Protein innocent bystander(gene name synonym)|uniprotkb:CG1403(orf name)|uniprotkb:Sep1(gene name)|psi-mi:Sep1(display_short)|uniprotkb:Diff6(gene name synonym)|uniprotkb:iby(gene name synonym) psi-mi:"MI:0096"(pull down) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16096836|imex:IM-22412-10|dip:DIP-196076E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477064.1|refseq:NP_724659.1|flybase:FBgn0013726|dip:DIP-60735N|ensemblmetazoa:FBgn0013726(gene)|ensemblmetazoa:FBtr0088792(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|ensemblmetazoa:FBtr0088793(transcript)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070938"(contractile ring)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0060271"(cilium assembly) ensemblmetazoa:FBgn0011710(gene)|ensemblmetazoa:FBtr0077198(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005940"(septin ring)|go:"GO:0007349"(cellularization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|refseq:NP_523430.1|flybase:FBgn0011710|dip:DIP-18454N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:AwSNOc8ecwdqxwA6z93hfsSa7g87227 rogid:owbyZvFu8+uF3t60BTm9IqquTL47227 rigid:XrgHLDppFcR9n2p3mS00l5APvOw false strep tag:c-c his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61553 uniprotkb:P68135 intact:EBI-2308857|uniprotkb:O09099|uniprotkb:O09156|uniprotkb:Q05DK3|uniprotkb:Q7TN32|uniprotkb:Q80V75|ensembl:ENSMUSP00000031565 intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020 psi-mi:fscn1_mouse(display_long)|uniprotkb:Fscn1(gene name)|psi-mi:Fscn1(display_short)|uniprotkb:Fan1(gene name synonym)|uniprotkb:Snl(gene name synonym)|uniprotkb:Singed-like protein(gene name synonym) psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16096817|imex:IM-22412-9|dip:DIP-196077E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032010.2|dip:DIP-54657N|ensembl:ENSMUSG00000029581(gene)|ensembl:ENSMUST00000031565(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030035"(microspike assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030046"(parallel actin filament bundle assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031253"(cell projection membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0043209"(myelin sheath)|go:"GO:0044393"(microspike)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|interpro:IPR008999(Actin_cross-linking)|interpro:IPR010431(Fascin)|interpro:IPR022768|interpro:IPR024703|interpro:IPR030146|mint:Q61553 rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:D+qdiRYJCXobCuZmdebrhb32jSI10090 rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986 rigid:fXZdJJ9ZHJ38Ncf7531ETU90OP8 false - alexa 488 label:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15019-1 uniprotkb:Q16181 intact:EBI-5279816|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 psi-mi:q15019-1(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:"MI:0096"(pull down) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16096795|imex:IM-22412-8|dip:DIP-191030E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|intact:EBI-741220(isoform-parent) refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rigid:f+fHwMdjRNrn265IovXHjdlp26s false his tag:n-n strep tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15019-1 uniprotkb:Q14141 intact:EBI-5279816|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 psi-mi:q15019-1(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:"MI:0096"(pull down) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16096795|imex:IM-22412-8|dip:DIP-191030E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|intact:EBI-741220(isoform-parent) ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rigid:f+fHwMdjRNrn265IovXHjdlp26s false his tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61553 uniprotkb:P68135 intact:EBI-2308857|uniprotkb:O09099|uniprotkb:O09156|uniprotkb:Q05DK3|uniprotkb:Q7TN32|uniprotkb:Q80V75|ensembl:ENSMUSP00000031565 intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020 psi-mi:fscn1_mouse(display_long)|uniprotkb:Fscn1(gene name)|psi-mi:Fscn1(display_short)|uniprotkb:Fan1(gene name synonym)|uniprotkb:Snl(gene name synonym)|uniprotkb:Singed-like protein(gene name synonym) psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:"MI:0953"(polymerization) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16096778|imex:IM-22412-7|dip:DIP-196077E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032010.2|dip:DIP-54657N|ensembl:ENSMUSG00000029581(gene)|ensembl:ENSMUST00000031565(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030035"(microspike assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030046"(parallel actin filament bundle assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031253"(cell projection membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0043209"(myelin sheath)|go:"GO:0044393"(microspike)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|interpro:IPR008999(Actin_cross-linking)|interpro:IPR010431(Fascin)|interpro:IPR022768|interpro:IPR024703|interpro:IPR030146|mint:Q61553 rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:D+qdiRYJCXobCuZmdebrhb32jSI10090 rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986 rigid:fXZdJJ9ZHJ38Ncf7531ETU90OP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40797 uniprotkb:P42207 intact:EBI-171301|uniprotkb:Q0E9F5|uniprotkb:Q9V385|ensemblmetazoa:FBpp0087869|ensemblmetazoa:FBpp0087870 intact:EBI-120528|uniprotkb:Q9VRH5|uniprotkb:Q8IQ47|ensemblmetazoa:FBpp0076897 psi-mi:pnut_drome(display_long)|uniprotkb:pnut(gene name)|psi-mi:pnut(display_short)|uniprotkb:CG8705(orf name) psi-mi:sept1_drome(display_long)|uniprotkb:DIFF6 protein homolog(gene name synonym)|uniprotkb:Protein innocent bystander(gene name synonym)|uniprotkb:CG1403(orf name)|uniprotkb:Sep1(gene name)|psi-mi:Sep1(display_short)|uniprotkb:Diff6(gene name synonym)|uniprotkb:iby(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16096876|imex:IM-22412-12|dip:DIP-196076E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477064.1|refseq:NP_724659.1|flybase:FBgn0013726|dip:DIP-60735N|ensemblmetazoa:FBgn0013726(gene)|ensemblmetazoa:FBtr0088792(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|ensemblmetazoa:FBtr0088793(transcript)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070938"(contractile ring)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0060271"(cilium assembly) ensemblmetazoa:FBgn0011710(gene)|ensemblmetazoa:FBtr0077198(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005940"(septin ring)|go:"GO:0007349"(cellularization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|refseq:NP_523430.1|flybase:FBgn0011710|dip:DIP-18454N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:AwSNOc8ecwdqxwA6z93hfsSa7g87227 rogid:owbyZvFu8+uF3t60BTm9IqquTL47227 rigid:XrgHLDppFcR9n2p3mS00l5APvOw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40797 uniprotkb:P54359 intact:EBI-171301|uniprotkb:Q0E9F5|uniprotkb:Q9V385|ensemblmetazoa:FBpp0087869|ensemblmetazoa:FBpp0087870 intact:EBI-188936|uniprotkb:Q24092|uniprotkb:Q9VDK8|ensemblmetazoa:FBpp0083352 psi-mi:pnut_drome(display_long)|uniprotkb:pnut(gene name)|psi-mi:pnut(display_short)|uniprotkb:CG8705(orf name) psi-mi:sept2_drome(display_long)|uniprotkb:Sep2(gene name)|psi-mi:Sep2(display_short)|uniprotkb:CG4173(orf name) psi-mi:"MI:0020"(transmission electron microscopy) Mavrakis et al. (2014) pubmed:24633326|doi:10.1038/ncb2921|imex:IM-22412 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16096876|imex:IM-22412-12|dip:DIP-196076E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477064.1|refseq:NP_724659.1|flybase:FBgn0013726|dip:DIP-60735N|ensemblmetazoa:FBgn0013726(gene)|ensemblmetazoa:FBtr0088792(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0007349"(cellularization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|ensemblmetazoa:FBtr0088793(transcript)|go:"GO:0031105"(septin complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070938"(contractile ring)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0060271"(cilium assembly) refseq:NP_524417.1|flybase:FBgn0014029|dip:DIP-20060N|ensemblmetazoa:FBgn0014029(gene)|ensemblmetazoa:FBtr0083945(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007295"(growth of a germarium-derived egg chamber)|go:"GO:0007349"(cellularization)|go:"GO:0007444"(imaginal disc development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:AwSNOc8ecwdqxwA6z93hfsSa7g87227 rogid:yZOoGT0rH7z1Sm3rbziG/xiMNMg7227 rigid:XrgHLDppFcR9n2p3mS00l5APvOw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)