#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8CII9 uniprotkb:Q9JIE6 intact:EBI-15887886|uniprotkb:Q9CRJ6|uniprotkb:Q9JIE7|uniprotkb:Q9JIQ7|uniprotkb:Q9JJH8|uniprotkb:Q9JMD5 intact:EBI-16096402|ensembl:ENSMUSP00000025237 psi-mi:crlf2_mouse(display_long)|uniprotkb:Crlf2(gene name)|psi-mi:Crlf2(display_short)|uniprotkb:Crlm2(gene name synonym)|uniprotkb:Tpte2(gene name synonym)|uniprotkb:Tslpr(gene name synonym)|uniprotkb:Cytokine receptor-like molecule 2(gene name synonym)|uniprotkb:Thymic stromal lymphopoietin protein receptor(gene name synonym)|uniprotkb:Type I cytokine receptor delta 1(gene name synonym) psi-mi:tslp_mouse(display_long)|uniprotkb:Tslp(gene name)|psi-mi:Tslp(display_short)|uniprotkb:Thymic stroma-derived lymphopoietin(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Verstraete et al. (2014) pubmed:24632570|doi:10.1038/nsmb.2794|imex:IM-22695 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16096419|imex:IM-22695-1|dip:DIP-196557E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006954"(inflammatory response)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0043235"(receptor complex)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|dip:DIP-59471N|reactome:R-MMU-1266695|refseq:NP_001158207.1|refseq:NP_057924.3 ensembl:ENSMUSG00000024379(gene)|ensembl:ENSMUST00000025237(transcript)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005125"(cytokine activity)|go:"GO:0005139"(interleukin-7 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071654"("positive regulation of chemokine (C-C motif) ligand 1 production")|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR029189|interpro:IPR038329|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|reactome:R-MMU-1266695|refseq:NP_067342.1|dip:DIP-60842N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:XFzBG1wIKIn3iYnQVt9lW/7R4Uc10090 rogid:AEE9DB3tcjPISUMHxy5/4lQ9SGU10090 rigid:QBtkNNnbyKKxkwgQVBBbDKcDROk false sufficient binding region:20-222 sufficient binding region:20-140 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CII9 uniprotkb:P16872 intact:EBI-15887886|uniprotkb:Q9CRJ6|uniprotkb:Q9JIE7|uniprotkb:Q9JIQ7|uniprotkb:Q9JJH8|uniprotkb:Q9JMD5 intact:EBI-15887934|ensembl:ENSMUSP00000003981|uniprotkb:Q9R0C1 psi-mi:crlf2_mouse(display_long)|uniprotkb:Crlf2(gene name)|psi-mi:Crlf2(display_short)|uniprotkb:Crlm2(gene name synonym)|uniprotkb:Tpte2(gene name synonym)|uniprotkb:Tslpr(gene name synonym)|uniprotkb:Cytokine receptor-like molecule 2(gene name synonym)|uniprotkb:Thymic stromal lymphopoietin protein receptor(gene name synonym)|uniprotkb:Type I cytokine receptor delta 1(gene name synonym) psi-mi:il7ra_mouse(display_long)|uniprotkb:Il7r(gene name)|psi-mi:Il7r(display_short) psi-mi:"MI:0071"(molecular sieving) Verstraete et al. (2014) pubmed:24632570|doi:10.1038/nsmb.2794|imex:IM-22695 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16096440|imex:IM-22695-2|dip:DIP-196556E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006954"(inflammatory response)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0043235"(receptor complex)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|dip:DIP-59471N|reactome:R-MMU-1266695|refseq:NP_001158207.1|refseq:NP_057924.3 ensembl:ENSMUSG00000003882(gene)|ensembl:ENSMUST00000003981(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030217"(T cell differentiation)|go:"GO:0033089"(positive regulation of T cell differentiation in thymus)|go:"GO:0042100"(B cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040997|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|rcsb pdb:5J12|reactome:R-MMU-1266695|reactome:R-MMU-8856825|reactome:R-MMU-8856828|refseq:NP_032398.3|dip:DIP-59472N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:XFzBG1wIKIn3iYnQVt9lW/7R4Uc10090 rogid:GDSHgY9FRfJZBHrICeo1f7nkJ8810090 rigid:IYMD4y/sfixEGfFejyPzuHlKXxY false sufficient binding region:20-222 sufficient binding region:21-239 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CII9 uniprotkb:Q9JIE6 intact:EBI-15887886|uniprotkb:Q9CRJ6|uniprotkb:Q9JIE7|uniprotkb:Q9JIQ7|uniprotkb:Q9JJH8|uniprotkb:Q9JMD5 intact:EBI-16096402|ensembl:ENSMUSP00000025237 psi-mi:crlf2_mouse(display_long)|uniprotkb:Crlf2(gene name)|psi-mi:Crlf2(display_short)|uniprotkb:Crlm2(gene name synonym)|uniprotkb:Tpte2(gene name synonym)|uniprotkb:Tslpr(gene name synonym)|uniprotkb:Cytokine receptor-like molecule 2(gene name synonym)|uniprotkb:Thymic stromal lymphopoietin protein receptor(gene name synonym)|uniprotkb:Type I cytokine receptor delta 1(gene name synonym) psi-mi:tslp_mouse(display_long)|uniprotkb:Tslp(gene name)|psi-mi:Tslp(display_short)|uniprotkb:Thymic stroma-derived lymphopoietin(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Verstraete et al. (2014) pubmed:24632570|doi:10.1038/nsmb.2794|imex:IM-22695 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16096440|imex:IM-22695-2|dip:DIP-196556E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006954"(inflammatory response)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0043235"(receptor complex)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|dip:DIP-59471N|reactome:R-MMU-1266695|refseq:NP_001158207.1|refseq:NP_057924.3 ensembl:ENSMUSG00000024379(gene)|ensembl:ENSMUST00000025237(transcript)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005125"(cytokine activity)|go:"GO:0005139"(interleukin-7 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071654"("positive regulation of chemokine (C-C motif) ligand 1 production")|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR029189|interpro:IPR038329|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|reactome:R-MMU-1266695|refseq:NP_067342.1|dip:DIP-60842N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:XFzBG1wIKIn3iYnQVt9lW/7R4Uc10090 rogid:AEE9DB3tcjPISUMHxy5/4lQ9SGU10090 rigid:IYMD4y/sfixEGfFejyPzuHlKXxY false sufficient binding region:20-222 sufficient binding region:20-140 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CII9 uniprotkb:Q9JIE6 intact:EBI-15887886|uniprotkb:Q9CRJ6|uniprotkb:Q9JIE7|uniprotkb:Q9JIQ7|uniprotkb:Q9JJH8|uniprotkb:Q9JMD5 intact:EBI-16096402|ensembl:ENSMUSP00000025237 psi-mi:crlf2_mouse(display_long)|uniprotkb:Crlf2(gene name)|psi-mi:Crlf2(display_short)|uniprotkb:Crlm2(gene name synonym)|uniprotkb:Tpte2(gene name synonym)|uniprotkb:Tslpr(gene name synonym)|uniprotkb:Cytokine receptor-like molecule 2(gene name synonym)|uniprotkb:Thymic stromal lymphopoietin protein receptor(gene name synonym)|uniprotkb:Type I cytokine receptor delta 1(gene name synonym) psi-mi:tslp_mouse(display_long)|uniprotkb:Tslp(gene name)|psi-mi:Tslp(display_short)|uniprotkb:Thymic stroma-derived lymphopoietin(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Verstraete et al. (2014) pubmed:24632570|doi:10.1038/nsmb.2794|imex:IM-22695 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16096506|imex:IM-22695-5|dip:DIP-196557E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006954"(inflammatory response)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0043235"(receptor complex)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|dip:DIP-59471N|reactome:R-MMU-1266695|refseq:NP_001158207.1|refseq:NP_057924.3 ensembl:ENSMUSG00000024379(gene)|ensembl:ENSMUST00000025237(transcript)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005125"(cytokine activity)|go:"GO:0005139"(interleukin-7 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071654"("positive regulation of chemokine (C-C motif) ligand 1 production")|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR029189|interpro:IPR038329|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|reactome:R-MMU-1266695|refseq:NP_067342.1|dip:DIP-60842N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:XFzBG1wIKIn3iYnQVt9lW/7R4Uc10090 rogid:AEE9DB3tcjPISUMHxy5/4lQ9SGU10090 rigid:QBtkNNnbyKKxkwgQVBBbDKcDROk false sufficient binding region:20-222 sufficient binding region:20-140 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CII9 uniprotkb:P16872 intact:EBI-15887886|uniprotkb:Q9CRJ6|uniprotkb:Q9JIE7|uniprotkb:Q9JIQ7|uniprotkb:Q9JJH8|uniprotkb:Q9JMD5 intact:EBI-15887934|ensembl:ENSMUSP00000003981|uniprotkb:Q9R0C1 psi-mi:crlf2_mouse(display_long)|uniprotkb:Crlf2(gene name)|psi-mi:Crlf2(display_short)|uniprotkb:Crlm2(gene name synonym)|uniprotkb:Tpte2(gene name synonym)|uniprotkb:Tslpr(gene name synonym)|uniprotkb:Cytokine receptor-like molecule 2(gene name synonym)|uniprotkb:Thymic stromal lymphopoietin protein receptor(gene name synonym)|uniprotkb:Type I cytokine receptor delta 1(gene name synonym) psi-mi:il7ra_mouse(display_long)|uniprotkb:Il7r(gene name)|psi-mi:Il7r(display_short) psi-mi:"MI:0114"(x-ray crystallography) Verstraete et al. (2014) pubmed:24632570|doi:10.1038/nsmb.2794|imex:IM-22695 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16096530|imex:IM-22695-6|dip:DIP-196556E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006954"(inflammatory response)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0043235"(receptor complex)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|dip:DIP-59471N|reactome:R-MMU-1266695|refseq:NP_001158207.1|refseq:NP_057924.3 ensembl:ENSMUSG00000003882(gene)|ensembl:ENSMUST00000003981(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030217"(T cell differentiation)|go:"GO:0033089"(positive regulation of T cell differentiation in thymus)|go:"GO:0042100"(B cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040997|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|rcsb pdb:5J12|reactome:R-MMU-1266695|reactome:R-MMU-8856825|reactome:R-MMU-8856828|refseq:NP_032398.3|dip:DIP-59472N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:XFzBG1wIKIn3iYnQVt9lW/7R4Uc10090 rogid:GDSHgY9FRfJZBHrICeo1f7nkJ8810090 rigid:IYMD4y/sfixEGfFejyPzuHlKXxY false sufficient binding region:20-222 sufficient binding region:21-239 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CII9 uniprotkb:Q9JIE6 intact:EBI-15887886|uniprotkb:Q9CRJ6|uniprotkb:Q9JIE7|uniprotkb:Q9JIQ7|uniprotkb:Q9JJH8|uniprotkb:Q9JMD5 intact:EBI-16096402|ensembl:ENSMUSP00000025237 psi-mi:crlf2_mouse(display_long)|uniprotkb:Crlf2(gene name)|psi-mi:Crlf2(display_short)|uniprotkb:Crlm2(gene name synonym)|uniprotkb:Tpte2(gene name synonym)|uniprotkb:Tslpr(gene name synonym)|uniprotkb:Cytokine receptor-like molecule 2(gene name synonym)|uniprotkb:Thymic stromal lymphopoietin protein receptor(gene name synonym)|uniprotkb:Type I cytokine receptor delta 1(gene name synonym) psi-mi:tslp_mouse(display_long)|uniprotkb:Tslp(gene name)|psi-mi:Tslp(display_short)|uniprotkb:Thymic stroma-derived lymphopoietin(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Verstraete et al. (2014) pubmed:24632570|doi:10.1038/nsmb.2794|imex:IM-22695 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16096530|imex:IM-22695-6|dip:DIP-196556E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006954"(inflammatory response)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0043235"(receptor complex)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|dip:DIP-59471N|reactome:R-MMU-1266695|refseq:NP_001158207.1|refseq:NP_057924.3 ensembl:ENSMUSG00000024379(gene)|ensembl:ENSMUST00000025237(transcript)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005125"(cytokine activity)|go:"GO:0005139"(interleukin-7 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071654"("positive regulation of chemokine (C-C motif) ligand 1 production")|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR029189|interpro:IPR038329|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|reactome:R-MMU-1266695|refseq:NP_067342.1|dip:DIP-60842N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:XFzBG1wIKIn3iYnQVt9lW/7R4Uc10090 rogid:AEE9DB3tcjPISUMHxy5/4lQ9SGU10090 rigid:IYMD4y/sfixEGfFejyPzuHlKXxY false sufficient binding region:20-222 sufficient binding region:20-140 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CII9 uniprotkb:P16872 intact:EBI-15887886|uniprotkb:Q9CRJ6|uniprotkb:Q9JIE7|uniprotkb:Q9JIQ7|uniprotkb:Q9JJH8|uniprotkb:Q9JMD5 intact:EBI-15887934|ensembl:ENSMUSP00000003981|uniprotkb:Q9R0C1 psi-mi:crlf2_mouse(display_long)|uniprotkb:Crlf2(gene name)|psi-mi:Crlf2(display_short)|uniprotkb:Crlm2(gene name synonym)|uniprotkb:Tpte2(gene name synonym)|uniprotkb:Tslpr(gene name synonym)|uniprotkb:Cytokine receptor-like molecule 2(gene name synonym)|uniprotkb:Thymic stromal lymphopoietin protein receptor(gene name synonym)|uniprotkb:Type I cytokine receptor delta 1(gene name synonym) psi-mi:il7ra_mouse(display_long)|uniprotkb:Il7r(gene name)|psi-mi:Il7r(display_short) psi-mi:"MI:0071"(molecular sieving) Verstraete et al. (2014) pubmed:24632570|doi:10.1038/nsmb.2794|imex:IM-22695 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16096554|imex:IM-22695-7|dip:DIP-196556E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006954"(inflammatory response)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0043235"(receptor complex)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|dip:DIP-59471N|reactome:R-MMU-1266695|refseq:NP_001158207.1|refseq:NP_057924.3 ensembl:ENSMUSG00000003882(gene)|ensembl:ENSMUST00000003981(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030217"(T cell differentiation)|go:"GO:0033089"(positive regulation of T cell differentiation in thymus)|go:"GO:0042100"(B cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040997|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|rcsb pdb:5J12|reactome:R-MMU-1266695|reactome:R-MMU-8856825|reactome:R-MMU-8856828|refseq:NP_032398.3|dip:DIP-59472N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:XFzBG1wIKIn3iYnQVt9lW/7R4Uc10090 rogid:GDSHgY9FRfJZBHrICeo1f7nkJ8810090 rigid:IYMD4y/sfixEGfFejyPzuHlKXxY false sufficient binding region:20-222 sufficient binding region:21-239 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CII9 uniprotkb:Q9JIE6 intact:EBI-15887886|uniprotkb:Q9CRJ6|uniprotkb:Q9JIE7|uniprotkb:Q9JIQ7|uniprotkb:Q9JJH8|uniprotkb:Q9JMD5 intact:EBI-16096402|ensembl:ENSMUSP00000025237 psi-mi:crlf2_mouse(display_long)|uniprotkb:Crlf2(gene name)|psi-mi:Crlf2(display_short)|uniprotkb:Crlm2(gene name synonym)|uniprotkb:Tpte2(gene name synonym)|uniprotkb:Tslpr(gene name synonym)|uniprotkb:Cytokine receptor-like molecule 2(gene name synonym)|uniprotkb:Thymic stromal lymphopoietin protein receptor(gene name synonym)|uniprotkb:Type I cytokine receptor delta 1(gene name synonym) psi-mi:tslp_mouse(display_long)|uniprotkb:Tslp(gene name)|psi-mi:Tslp(display_short)|uniprotkb:Thymic stroma-derived lymphopoietin(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Verstraete et al. (2014) pubmed:24632570|doi:10.1038/nsmb.2794|imex:IM-22695 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16096554|imex:IM-22695-7|dip:DIP-196556E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006954"(inflammatory response)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0043235"(receptor complex)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|dip:DIP-59471N|reactome:R-MMU-1266695|refseq:NP_001158207.1|refseq:NP_057924.3 ensembl:ENSMUSG00000024379(gene)|ensembl:ENSMUST00000025237(transcript)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005125"(cytokine activity)|go:"GO:0005139"(interleukin-7 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071654"("positive regulation of chemokine (C-C motif) ligand 1 production")|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR029189|interpro:IPR038329|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|reactome:R-MMU-1266695|refseq:NP_067342.1|dip:DIP-60842N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:XFzBG1wIKIn3iYnQVt9lW/7R4Uc10090 rogid:AEE9DB3tcjPISUMHxy5/4lQ9SGU10090 rigid:IYMD4y/sfixEGfFejyPzuHlKXxY false sufficient binding region:20-222 sufficient binding region:20-140 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CII9 uniprotkb:Q9JIE6 intact:EBI-15887886|uniprotkb:Q9CRJ6|uniprotkb:Q9JIE7|uniprotkb:Q9JIQ7|uniprotkb:Q9JJH8|uniprotkb:Q9JMD5 intact:EBI-16096402|ensembl:ENSMUSP00000025237 psi-mi:crlf2_mouse(display_long)|uniprotkb:Crlf2(gene name)|psi-mi:Crlf2(display_short)|uniprotkb:Crlm2(gene name synonym)|uniprotkb:Tpte2(gene name synonym)|uniprotkb:Tslpr(gene name synonym)|uniprotkb:Cytokine receptor-like molecule 2(gene name synonym)|uniprotkb:Thymic stromal lymphopoietin protein receptor(gene name synonym)|uniprotkb:Type I cytokine receptor delta 1(gene name synonym) psi-mi:tslp_mouse(display_long)|uniprotkb:Tslp(gene name)|psi-mi:Tslp(display_short)|uniprotkb:Thymic stroma-derived lymphopoietin(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Verstraete et al. (2014) pubmed:24632570|doi:10.1038/nsmb.2794|imex:IM-22695 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16096578|imex:IM-22695-8|dip:DIP-196557E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006954"(inflammatory response)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0043235"(receptor complex)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|dip:DIP-59471N|reactome:R-MMU-1266695|refseq:NP_001158207.1|refseq:NP_057924.3 ensembl:ENSMUSG00000024379(gene)|ensembl:ENSMUST00000025237(transcript)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005125"(cytokine activity)|go:"GO:0005139"(interleukin-7 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071654"("positive regulation of chemokine (C-C motif) ligand 1 production")|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR029189|interpro:IPR038329|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|reactome:R-MMU-1266695|refseq:NP_067342.1|dip:DIP-60842N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:XFzBG1wIKIn3iYnQVt9lW/7R4Uc10090 rogid:AEE9DB3tcjPISUMHxy5/4lQ9SGU10090 rigid:QBtkNNnbyKKxkwgQVBBbDKcDROk false sufficient binding region:20-222 sufficient binding region:20-140 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CII9 uniprotkb:Q9JIE6 intact:EBI-15887886|uniprotkb:Q9CRJ6|uniprotkb:Q9JIE7|uniprotkb:Q9JIQ7|uniprotkb:Q9JJH8|uniprotkb:Q9JMD5 intact:EBI-16096402|ensembl:ENSMUSP00000025237 psi-mi:crlf2_mouse(display_long)|uniprotkb:Crlf2(gene name)|psi-mi:Crlf2(display_short)|uniprotkb:Crlm2(gene name synonym)|uniprotkb:Tpte2(gene name synonym)|uniprotkb:Tslpr(gene name synonym)|uniprotkb:Cytokine receptor-like molecule 2(gene name synonym)|uniprotkb:Thymic stromal lymphopoietin protein receptor(gene name synonym)|uniprotkb:Type I cytokine receptor delta 1(gene name synonym) psi-mi:tslp_mouse(display_long)|uniprotkb:Tslp(gene name)|psi-mi:Tslp(display_short)|uniprotkb:Thymic stroma-derived lymphopoietin(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Verstraete et al. (2014) pubmed:24632570|doi:10.1038/nsmb.2794|imex:IM-22695 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16096599|imex:IM-22695-9|dip:DIP-196557E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006954"(inflammatory response)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0043235"(receptor complex)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|dip:DIP-59471N|reactome:R-MMU-1266695|refseq:NP_001158207.1|refseq:NP_057924.3 ensembl:ENSMUSG00000024379(gene)|ensembl:ENSMUST00000025237(transcript)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005125"(cytokine activity)|go:"GO:0005139"(interleukin-7 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071654"("positive regulation of chemokine (C-C motif) ligand 1 production")|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR029189|interpro:IPR038329|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|reactome:R-MMU-1266695|refseq:NP_067342.1|dip:DIP-60842N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:XFzBG1wIKIn3iYnQVt9lW/7R4Uc10090 rogid:AEE9DB3tcjPISUMHxy5/4lQ9SGU10090 rigid:QBtkNNnbyKKxkwgQVBBbDKcDROk false sufficient binding region:20-222 sufficient binding region:20-140 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16872 uniprotkb:Q9JIE6 intact:EBI-15887934|ensembl:ENSMUSP00000003981|uniprotkb:Q9R0C1 intact:EBI-16096402|ensembl:ENSMUSP00000025237 psi-mi:il7ra_mouse(display_long)|uniprotkb:Il7r(gene name)|psi-mi:Il7r(display_short) psi-mi:tslp_mouse(display_long)|uniprotkb:Tslp(gene name)|psi-mi:Tslp(display_short)|uniprotkb:Thymic stroma-derived lymphopoietin(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Verstraete et al. (2014) pubmed:24632570|doi:10.1038/nsmb.2794|imex:IM-22695 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16096485|imex:IM-22695-4|dip:DIP-196558E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003882(gene)|ensembl:ENSMUST00000003981(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030217"(T cell differentiation)|go:"GO:0033089"(positive regulation of T cell differentiation in thymus)|go:"GO:0042100"(B cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040997|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|rcsb pdb:5J12|reactome:R-MMU-1266695|reactome:R-MMU-8856825|reactome:R-MMU-8856828|refseq:NP_032398.3|dip:DIP-59472N ensembl:ENSMUSG00000024379(gene)|ensembl:ENSMUST00000025237(transcript)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005125"(cytokine activity)|go:"GO:0005139"(interleukin-7 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071654"("positive regulation of chemokine (C-C motif) ligand 1 production")|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR029189|interpro:IPR038329|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|reactome:R-MMU-1266695|refseq:NP_067342.1|dip:DIP-60842N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:GDSHgY9FRfJZBHrICeo1f7nkJ8810090 rogid:AEE9DB3tcjPISUMHxy5/4lQ9SGU10090 rigid:HeCwaVyud67bcCd4adzNOMMgkLU false sufficient binding region:21-239 sufficient binding region:20-140 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CII9 uniprotkb:Q9JIE6 intact:EBI-15887886|uniprotkb:Q9CRJ6|uniprotkb:Q9JIE7|uniprotkb:Q9JIQ7|uniprotkb:Q9JJH8|uniprotkb:Q9JMD5 intact:EBI-16096402|ensembl:ENSMUSP00000025237 psi-mi:crlf2_mouse(display_long)|uniprotkb:Crlf2(gene name)|psi-mi:Crlf2(display_short)|uniprotkb:Crlm2(gene name synonym)|uniprotkb:Tpte2(gene name synonym)|uniprotkb:Tslpr(gene name synonym)|uniprotkb:Cytokine receptor-like molecule 2(gene name synonym)|uniprotkb:Thymic stromal lymphopoietin protein receptor(gene name synonym)|uniprotkb:Type I cytokine receptor delta 1(gene name synonym) psi-mi:tslp_mouse(display_long)|uniprotkb:Tslp(gene name)|psi-mi:Tslp(display_short)|uniprotkb:Thymic stroma-derived lymphopoietin(gene name synonym) psi-mi:"MI:0067"(light scattering) Verstraete et al. (2014) pubmed:24632570|doi:10.1038/nsmb.2794|imex:IM-22695 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16096464|imex:IM-22695-3|dip:DIP-196557E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006954"(inflammatory response)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0043235"(receptor complex)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|dip:DIP-59471N|reactome:R-MMU-1266695|refseq:NP_001158207.1|refseq:NP_057924.3 ensembl:ENSMUSG00000024379(gene)|ensembl:ENSMUST00000025237(transcript)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005125"(cytokine activity)|go:"GO:0005139"(interleukin-7 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071654"("positive regulation of chemokine (C-C motif) ligand 1 production")|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR029189|interpro:IPR038329|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|reactome:R-MMU-1266695|refseq:NP_067342.1|dip:DIP-60842N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:XFzBG1wIKIn3iYnQVt9lW/7R4Uc10090 rogid:AEE9DB3tcjPISUMHxy5/4lQ9SGU10090 rigid:QBtkNNnbyKKxkwgQVBBbDKcDROk false sufficient binding region:20-222 sufficient binding region:20-140 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CII9 uniprotkb:P16872 intact:EBI-15887886|uniprotkb:Q9CRJ6|uniprotkb:Q9JIE7|uniprotkb:Q9JIQ7|uniprotkb:Q9JJH8|uniprotkb:Q9JMD5 intact:EBI-15887934|ensembl:ENSMUSP00000003981|uniprotkb:Q9R0C1 psi-mi:crlf2_mouse(display_long)|uniprotkb:Crlf2(gene name)|psi-mi:Crlf2(display_short)|uniprotkb:Crlm2(gene name synonym)|uniprotkb:Tpte2(gene name synonym)|uniprotkb:Tslpr(gene name synonym)|uniprotkb:Cytokine receptor-like molecule 2(gene name synonym)|uniprotkb:Thymic stromal lymphopoietin protein receptor(gene name synonym)|uniprotkb:Type I cytokine receptor delta 1(gene name synonym) psi-mi:il7ra_mouse(display_long)|uniprotkb:Il7r(gene name)|psi-mi:Il7r(display_short) psi-mi:"MI:0067"(light scattering) Verstraete et al. (2014) pubmed:24632570|doi:10.1038/nsmb.2794|imex:IM-22695 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16096620|imex:IM-22695-10|dip:DIP-196556E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006954"(inflammatory response)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0043235"(receptor complex)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|dip:DIP-59471N|reactome:R-MMU-1266695|refseq:NP_001158207.1|refseq:NP_057924.3 ensembl:ENSMUSG00000003882(gene)|ensembl:ENSMUST00000003981(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030217"(T cell differentiation)|go:"GO:0033089"(positive regulation of T cell differentiation in thymus)|go:"GO:0042100"(B cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040997|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|rcsb pdb:5J12|reactome:R-MMU-1266695|reactome:R-MMU-8856825|reactome:R-MMU-8856828|refseq:NP_032398.3|dip:DIP-59472N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:XFzBG1wIKIn3iYnQVt9lW/7R4Uc10090 rogid:GDSHgY9FRfJZBHrICeo1f7nkJ8810090 rigid:IYMD4y/sfixEGfFejyPzuHlKXxY false sufficient binding region:20-222 sufficient binding region:21-239 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CII9 uniprotkb:Q9JIE6 intact:EBI-15887886|uniprotkb:Q9CRJ6|uniprotkb:Q9JIE7|uniprotkb:Q9JIQ7|uniprotkb:Q9JJH8|uniprotkb:Q9JMD5 intact:EBI-16096402|ensembl:ENSMUSP00000025237 psi-mi:crlf2_mouse(display_long)|uniprotkb:Crlf2(gene name)|psi-mi:Crlf2(display_short)|uniprotkb:Crlm2(gene name synonym)|uniprotkb:Tpte2(gene name synonym)|uniprotkb:Tslpr(gene name synonym)|uniprotkb:Cytokine receptor-like molecule 2(gene name synonym)|uniprotkb:Thymic stromal lymphopoietin protein receptor(gene name synonym)|uniprotkb:Type I cytokine receptor delta 1(gene name synonym) psi-mi:tslp_mouse(display_long)|uniprotkb:Tslp(gene name)|psi-mi:Tslp(display_short)|uniprotkb:Thymic stroma-derived lymphopoietin(gene name synonym) psi-mi:"MI:0067"(light scattering) Verstraete et al. (2014) pubmed:24632570|doi:10.1038/nsmb.2794|imex:IM-22695 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16096620|imex:IM-22695-10|dip:DIP-196556E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006954"(inflammatory response)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0043235"(receptor complex)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|dip:DIP-59471N|reactome:R-MMU-1266695|refseq:NP_001158207.1|refseq:NP_057924.3 ensembl:ENSMUSG00000024379(gene)|ensembl:ENSMUST00000025237(transcript)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005125"(cytokine activity)|go:"GO:0005139"(interleukin-7 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071654"("positive regulation of chemokine (C-C motif) ligand 1 production")|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR029189|interpro:IPR038329|rcsb pdb:4NN5|rcsb pdb:4NN6|rcsb pdb:4NN7|reactome:R-MMU-1266695|refseq:NP_067342.1|dip:DIP-60842N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:XFzBG1wIKIn3iYnQVt9lW/7R4Uc10090 rogid:AEE9DB3tcjPISUMHxy5/4lQ9SGU10090 rigid:IYMD4y/sfixEGfFejyPzuHlKXxY false sufficient binding region:20-222 sufficient binding region:20-140 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)