#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P35732 uniprotkb:P32849 intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C intact:EBI-14773|ensemblfungi:YLR032W|uniprotkb:D6VY34 psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:rad5_yeast(display_long)|uniprotkb:REV2(gene name synonym)|uniprotkb:YLR032W(locus name)|uniprotkb:RAD5(gene name)|psi-mi:RAD5(display_short)|uniprotkb:SNM2(gene name synonym)|uniprotkb:Radiation sensitivity protein 5(gene name synonym)|uniprotkb:Revertibility protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Daraba et al. (2014) pubmed:24465179|doi:10.1371/journal.pbio.1001771|imex:IM-22346 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16092004|imex:IM-22346-1|dip:DIP-195864E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 refseq:NP_013132.1|sgd:S000004022|ensemblfungi:YLR032W(gene)|ensemblfungi:YLR032W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0070615"|go:"GO:0070987"(error-free translesion synthesis)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|rcsb pdb:5YRQ|reactome:R-SCE-8866654|go:"GO:0009378"(four-way junction helicase activity)|dip:DIP-5830N|mint:P32849 psi-mi:"MI:0465"(dip) crc64:05734E2D0B7389AC crc64:226B720097433EE2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 rogid:gKjd6r+cPzkuJUjpYjt5Szl+OLI559292 rigid:GuKSuqNqNPnR+6jaEjrwrFUcunA false - calmodulin binding peptide plus protein a tag:c-c - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P47110 uniprotkb:P12689 intact:EBI-6084|uniprotkb:D6VWL4|ensemblfungi:YJR043C intact:EBI-14951|uniprotkb:Q12323|uniprotkb:D6W341|ensemblfungi:YOR346W psi-mi:dpod3_yeast(display_long)|uniprotkb:POL32(gene name)|psi-mi:POL32(display_short)|uniprotkb:J1626(orf name)|uniprotkb:YJR043C(locus name) psi-mi:rev1_yeast(display_long)|uniprotkb:REV1(gene name)|psi-mi:REV1(display_short)|uniprotkb:YOR346W(locus name)|uniprotkb:O6339(orf name)|uniprotkb:Reversionless protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Daraba et al. (2014) pubmed:24465179|doi:10.1371/journal.pbio.1001771|imex:IM-22346 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16092023|imex:IM-22346-2|dip:DIP-195866E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012577.1|sgd:S000003804|dip:DIP-2523N|mint:P47110|ensemblfungi:YJR043C(gene)|ensemblfungi:YJR043C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006277"(DNA amplification)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|rcsb pdb:6P1H|rcsb pdb:6V8P|rcsb pdb:6V93|rcsb pdb:7LXD refseq:NP_014991.1|sgd:S000005873|ensemblfungi:YOR346W(gene)|ensemblfungi:YOR346W_mRNA(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0017125"(deoxycytidyl transferase activity)|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5655862|go:"GO:0046872"(metal ion binding)|go:"GO:0070987"(error-free translesion synthesis)|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR001357(BRCT)|interpro:IPR012112(DNA repair protein, Rev1)|interpro:IPR017961|interpro:IPR036420|interpro:IPR036775|interpro:IPR043128|interpro:IPR043502|rcsb pdb:2AQ4|rcsb pdb:2M2I|rcsb pdb:3BJY|rcsb pdb:3OSP|rcsb pdb:4ID3|go:"GO:0042276"(error-prone translesion synthesis)|rcsb pdb:5UMV|rcsb pdb:5VX7|rcsb pdb:5WM1|rcsb pdb:5WM8|rcsb pdb:5WMB|rcsb pdb:5YRQ|rcsb pdb:6X6Z|rcsb pdb:6X70|rcsb pdb:6X71|rcsb pdb:6X72|rcsb pdb:6X73|rcsb pdb:6X74|rcsb pdb:6X75|rcsb pdb:6X76|rcsb pdb:6X77|reactome:R-SCE-110312|dip:DIP-1000N|mint:P12689 psi-mi:"MI:0465"(dip) crc64:D0B9CC52F26E20B2 crc64:330E30A27F8300BE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:02A0trLDLwbbYcE+AONHGaJ/XHM559292 rogid:zfltgu1OtBv16RiWjBl60OjgPQw559292 rigid:uYJLppEl8dc53xmgjYAyCufCasw false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P47110 uniprotkb:P46957 intact:EBI-6084|uniprotkb:D6VWL4|ensemblfungi:YJR043C intact:EBI-6080|uniprotkb:D6VWI1|ensemblfungi:YJR006W psi-mi:dpod3_yeast(display_long)|uniprotkb:POL32(gene name)|psi-mi:POL32(display_short)|uniprotkb:J1626(orf name)|uniprotkb:YJR043C(locus name) psi-mi:dpod2_yeast(display_long)|uniprotkb:POL31(gene name)|psi-mi:POL31(display_short)|uniprotkb:HUS2(gene name synonym)|uniprotkb:SDP5(gene name synonym)|uniprotkb:YJR006W(locus name)|uniprotkb:J1427(orf name)|uniprotkb:YJR83.7(orf name)|uniprotkb:Hydroxyurea-sensitive protein 2(gene name synonym)|uniprotkb:HYS2(gene name synonym) psi-mi:"MI:0096"(pull down) Daraba et al. (2014) pubmed:24465179|doi:10.1371/journal.pbio.1001771|imex:IM-22346 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16092023|imex:IM-22346-2|dip:DIP-195866E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012577.1|sgd:S000003804|dip:DIP-2523N|mint:P47110|ensemblfungi:YJR043C(gene)|ensemblfungi:YJR043C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006277"(DNA amplification)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|rcsb pdb:6P1H|rcsb pdb:6V8P|rcsb pdb:6V93|rcsb pdb:7LXD refseq:NP_012539.1|sgd:S000003766|dip:DIP-2525N|mint:P46957|ensemblfungi:YJR006W(gene)|ensemblfungi:YJR006W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0042575"(DNA polymerase complex)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR024826|interpro:IPR040663|interpro:IPR041863|rcsb pdb:6P1H|rcsb pdb:6V8P|rcsb pdb:6V93|rcsb pdb:7LXD|reactome:R-SCE-69166|reactome:R-SCE-69183 psi-mi:"MI:0465"(dip) crc64:D0B9CC52F26E20B2 crc64:F9E200BFE97A2C07 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:02A0trLDLwbbYcE+AONHGaJ/XHM559292 rogid:/snR2U+Lgzyzq1V9PZG01x39304559292 rigid:uYJLppEl8dc53xmgjYAyCufCasw false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P15436 intact:EBI-19797 intact:EBI-6134|uniprotkb:D6VRP8|ensemblfungi:YDL102W dip:DIP-1549N|uniprotkb:P04838|uniprotkb:Q6LA96 psi-mi:dpod_yeast(display_long)|uniprotkb:POL3(gene name)|psi-mi:POL3(display_short)|uniprotkb:CDC2(gene name synonym)|uniprotkb:TEX1(gene name synonym)|uniprotkb:YDL102W(locus name)|uniprotkb:D2366(orf name)|uniprotkb:DNA polymerase III(gene name synonym)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym) psi-mi:ubiq_yeast(display_short)|psi-mi:EBI-19797(display_long)|uniprotkb:UBI1(gene name)|psi-mi:UBI1(display_short)|uniprotkb:RPL40A(gene name synonym)|uniprotkb:YIL148W(locus name)|uniprotkb:UBI2(gene name)|psi-mi:UBI2(display_short)|uniprotkb:RPL40B(gene name synonym)|uniprotkb:YKR094C(locus name)|uniprotkb:UBI3(gene name)|psi-mi:UBI3(display_short)|uniprotkb:RPS31(gene name synonym)|uniprotkb:YLR167W(locus name)|uniprotkb:L9470.14(orf name)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name) psi-mi:"MI:0096"(pull down) Daraba et al. (2014) pubmed:24465179|doi:10.1371/journal.pbio.1001771|imex:IM-22346 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16092043|imex:IM-22346-3|dip:DIP-195865E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010181.2|sgd:S000002260|dip:DIP-2524N|mint:P15436|ensemblfungi:YDL102W(gene)|ensemblfungi:YDL102W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017964|interpro:IPR023211|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|rcsb pdb:3IAY|rcsb pdb:6P1H|rcsb pdb:7KC0|reactome:R-SCE-69166|reactome:R-SCE-69183 sgd:S000001410(RPL40A)|sgd:S000001802(RPL40B)|sgd:S000004157(RPS31)|sgd:S000003962(UBI4)|uniprotkb:P61864(see-also)|refseq:NP_012118.1|refseq:NP_013020.1|refseq:NP_013061.1|refseq:NP_013268.1|ensembl:YIL148W|ensembl:YKR094C|ensembl:YLR167W|go:"GO:0005515"(protein binding)|interpro:IPR000626(Ubiquitin)|cygd:YLR167w|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0005739"(mitochondrion)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0006412"(translation)|ensembl:YLL039C|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|cygd:YIL148w|cygd:YKR094c|cygd:YLL039c|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:3CMM|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3MHS|rcsb pdb:2KDI psi-mi:"MI:0465"(dip) crc64:16E4245C5DCC66DB no-uniprot-update:obsolete protein full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/15 rogid:B6UmbmYRvxvUeMx9GmQ/nLy81+M559292 rogid:sUFDb7kGedoC/k80bI4sjOaMLHs4932 rigid:NKwxaE1ctDzZVJiJ7ecDOBfUDSI false ha tag:c-c his tag:0-0 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)