#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8C0V1 uniprotkb:O70576 intact:EBI-11707325|uniprotkb:A1L2Z9|uniprotkb:E9QPF2|uniprotkb:Q14CI1|uniprotkb:Q8C0N5|ensembl:ENSMUSP00000067324 intact:EBI-8571608|ensembl:ENSMUSP00000040945|ensembl:ENSMUSP00000125523|intact:UNK-5365402|uniprotkb:B2RSV0 psi-mi:terb1_mouse(display_long)|uniprotkb:Terb1(gene name)|psi-mi:Terb1(display_short)|uniprotkb:Ccdc79(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym) psi-mi:stag3_mouse(display_long)|uniprotkb:Stromalin-3(gene name synonym)|uniprotkb:Stag3(gene name)|psi-mi:Stag3(display_short)|uniprotkb:Stromal antigen 3(gene name synonym)|uniprotkb:SCC3 homolog 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shibuya et al. (2014) pubmed:24413433|doi:10.1038/ncb2896|imex:IM-22407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16089819|imex:IM-22407-1|dip:DIP-196057E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_851289.2|refseq:XP_006531157.1|ensembl:ENSMUSG00000052616(gene)|ensembl:ENSMUST00000064576(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|interpro:IPR000225(Armadillo)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042359|rcsb pdb:1X58|interpro:IPR001005(SANT, DNA-binding)|refseq:XP_017168345.1|dip:DIP-60728N refseq:XP_011239250.1|ensembl:ENSMUSG00000036928(gene)|ensembl:ENSMUST00000048028(transcript)|ensembl:ENSMUST00000162245(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0000802"(transverse filament)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007065"(male meiosis sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0008278"(cohesin complex)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0034991"(nuclear meiotic cohesin complex)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:O70576|refseq:XP_006504659.1|refseq:NP_058660.2|dip:DIP-60731N psi-mi:"MI:0465"(dip) - function:Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I|comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:fjP/AyqiLX9oFpDG6/ZPjI2Qu5I10090 rogid:VStlV0vm44TtcEnvNQTLPTFy2ok10090 rigid:4G6RITBzcDyo+uzZnmOCdPUuSWs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8C0V1 uniprotkb:Q80VJ8 intact:EBI-11707325|uniprotkb:A1L2Z9|uniprotkb:E9QPF2|uniprotkb:Q14CI1|uniprotkb:Q8C0N5|ensembl:ENSMUSP00000067324 intact:EBI-11666341|uniprotkb:E9QNS3|uniprotkb:E9QQ69|ensembl:ENSMUSP00000113616 psi-mi:terb1_mouse(display_long)|uniprotkb:Terb1(gene name)|psi-mi:Terb1(display_short)|uniprotkb:Ccdc79(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym) psi-mi:kash5_mouse(display_long)|uniprotkb:Kash5(gene name)|psi-mi:Kash5(display_short)|uniprotkb:Ccdc155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shibuya et al. (2014) pubmed:24413433|doi:10.1038/ncb2896|imex:IM-22407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16089819|imex:IM-22407-1|dip:DIP-196057E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_851289.2|refseq:XP_006531157.1|ensembl:ENSMUSG00000052616(gene)|ensembl:ENSMUST00000064576(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|interpro:IPR000225(Armadillo)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042359|rcsb pdb:1X58|interpro:IPR001005(SANT, DNA-binding)|refseq:XP_017168345.1|dip:DIP-60728N refseq:NP_958762.2|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|ensembl:ENSMUSG00000038292(gene)|ensembl:ENSMUST00000121017(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|dip:DIP-60733N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:fjP/AyqiLX9oFpDG6/ZPjI2Qu5I10090 rogid:uf9xEYfbOvC/6wkrSfEafIRt6L810090 rigid:4G6RITBzcDyo+uzZnmOCdPUuSWs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8C0V1 uniprotkb:Q9D666 intact:EBI-11707325|uniprotkb:A1L2Z9|uniprotkb:E9QPF2|uniprotkb:Q14CI1|uniprotkb:Q8C0N5|ensembl:ENSMUSP00000067324 intact:EBI-6752574|ensembl:ENSMUSP00000056655|uniprotkb:Q3TIW3|uniprotkb:Q3TV96|uniprotkb:Q6B4H0|uniprotkb:Q80SU8|uniprotkb:Q8BZ99|uniprotkb:Q99P23|uniprotkb:D3Z0V9 psi-mi:terb1_mouse(display_long)|uniprotkb:Terb1(gene name)|psi-mi:Terb1(display_short)|uniprotkb:Ccdc79(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym) psi-mi:sun1_mouse(display_long)|uniprotkb:Sun1(gene name)|psi-mi:Sun1(display_short)|uniprotkb:Unc84a(gene name synonym)|uniprotkb:Protein unc-84 homolog A(gene name synonym)|uniprotkb:Sad1/unc-84 protein-like 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shibuya et al. (2014) pubmed:24413433|doi:10.1038/ncb2896|imex:IM-22407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16089819|imex:IM-22407-1|dip:DIP-196057E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_851289.2|refseq:XP_006531157.1|ensembl:ENSMUSG00000052616(gene)|ensembl:ENSMUST00000064576(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|interpro:IPR000225(Armadillo)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042359|rcsb pdb:1X58|interpro:IPR001005(SANT, DNA-binding)|refseq:XP_017168345.1|dip:DIP-60728N ensembl:ENSMUSG00000036817(gene)|ensembl:ENSMUST00000058716(transcript)|go:"GO:0001503"(ossification)|go:"GO:0002081"(outer acrosomal membrane)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051642"(centrosome localization)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR018539|interpro:IPR032680|interpro:IPR040994|mint:Q9D666|rcsb pdb:5YWZ|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|refseq:NP_001243044.1|refseq:NP_001243045.1|refseq:NP_001243046.1|refseq:NP_001243047.1|refseq:NP_077771.1|dip:DIP-60732N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:fjP/AyqiLX9oFpDG6/ZPjI2Qu5I10090 rogid:GqqeG7DaPNhq8uKIbPelHOotEok10090 rigid:4G6RITBzcDyo+uzZnmOCdPUuSWs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8C0V1 uniprotkb:P70371 intact:EBI-11707325|uniprotkb:A1L2Z9|uniprotkb:E9QPF2|uniprotkb:Q14CI1|uniprotkb:Q8C0N5|ensembl:ENSMUSP00000067324 intact:EBI-6919183|ensembl:ENSMUSP00000140744|uniprotkb:Q9CY71 psi-mi:terb1_mouse(display_long)|uniprotkb:Terb1(gene name)|psi-mi:Terb1(display_short)|uniprotkb:Ccdc79(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym) psi-mi:terf1_mouse(display_long)|uniprotkb:Terf1(gene name)|psi-mi:Terf1(display_short)|uniprotkb:Trf1(gene name synonym)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shibuya et al. (2014) pubmed:24413433|doi:10.1038/ncb2896|imex:IM-22407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16089819|imex:IM-22407-1|dip:DIP-196057E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_851289.2|refseq:XP_006531157.1|ensembl:ENSMUSG00000052616(gene)|ensembl:ENSMUST00000064576(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|interpro:IPR000225(Armadillo)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042359|rcsb pdb:1X58|interpro:IPR001005(SANT, DNA-binding)|refseq:XP_017168345.1|dip:DIP-60728N ensembl:ENSMUSG00000025925(gene)|ensembl:ENSMUST00000188371(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0051301"(cell division)|go:"GO:0005654"(nucleoplasm)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P70371|reactome:R-MMU-110330|reactome:R-MMU-110331|reactome:R-MMU-171319|reactome:R-MMU-174411|reactome:R-MMU-174414|reactome:R-MMU-174417|reactome:R-MMU-174430|reactome:R-MMU-174437|reactome:R-MMU-2559586|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|reactome:R-MMU-9670095|refseq:NP_033378.1|dip:DIP-44231N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:fjP/AyqiLX9oFpDG6/ZPjI2Qu5I10090 rogid:jpK0DXdrNcuBqR96dkp45t/W5+M10090 rigid:4G6RITBzcDyo+uzZnmOCdPUuSWs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P70371 uniprotkb:Q8C0V1-1 intact:EBI-6919183|ensembl:ENSMUSP00000140744|uniprotkb:Q9CY71 intact:EBI-16089839|ensembl:ENSMUSP00000067324 psi-mi:terf1_mouse(display_long)|uniprotkb:Terf1(gene name)|psi-mi:Terf1(display_short)|uniprotkb:Trf1(gene name synonym)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym) psi-mi:q8c0v1-1(display_long)|uniprotkb:Terb1(gene name)|psi-mi:Terb1(display_short)|uniprotkb:Ccdc79(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shibuya et al. (2014) pubmed:24413433|doi:10.1038/ncb2896|imex:IM-22407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16089885|imex:IM-22407-4|dip:DIP-196060E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025925(gene)|ensembl:ENSMUST00000188371(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0051301"(cell division)|go:"GO:0005654"(nucleoplasm)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P70371|reactome:R-MMU-110330|reactome:R-MMU-110331|reactome:R-MMU-171319|reactome:R-MMU-174411|reactome:R-MMU-174414|reactome:R-MMU-174417|reactome:R-MMU-174430|reactome:R-MMU-174437|reactome:R-MMU-2559586|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|reactome:R-MMU-9670095|refseq:NP_033378.1|dip:DIP-44231N ensembl:ENSMUSG00000052616(gene)|ensembl:ENSMUST00000064576(transcript)|intact:EBI-11707325(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:jpK0DXdrNcuBqR96dkp45t/W5+M10090 rogid:fjP/AyqiLX9oFpDG6/ZPjI2Qu5I10090 rigid:t2osH9lcOrNl8N0SR6RiIFm9zHs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9D666 uniprotkb:Q8C0V1 intact:EBI-6752574|ensembl:ENSMUSP00000056655|uniprotkb:Q3TIW3|uniprotkb:Q3TV96|uniprotkb:Q6B4H0|uniprotkb:Q80SU8|uniprotkb:Q8BZ99|uniprotkb:Q99P23|uniprotkb:D3Z0V9 intact:EBI-11707325|uniprotkb:A1L2Z9|uniprotkb:E9QPF2|uniprotkb:Q14CI1|uniprotkb:Q8C0N5|ensembl:ENSMUSP00000067324 psi-mi:sun1_mouse(display_long)|uniprotkb:Sun1(gene name)|psi-mi:Sun1(display_short)|uniprotkb:Unc84a(gene name synonym)|uniprotkb:Protein unc-84 homolog A(gene name synonym)|uniprotkb:Sad1/unc-84 protein-like 1(gene name synonym) psi-mi:terb1_mouse(display_long)|uniprotkb:Terb1(gene name)|psi-mi:Terb1(display_short)|uniprotkb:Ccdc79(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shibuya et al. (2014) pubmed:24413433|doi:10.1038/ncb2896|imex:IM-22407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16089868|imex:IM-22407-3|dip:DIP-196061E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000036817(gene)|ensembl:ENSMUST00000058716(transcript)|go:"GO:0001503"(ossification)|go:"GO:0002081"(outer acrosomal membrane)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051642"(centrosome localization)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR018539|interpro:IPR032680|interpro:IPR040994|mint:Q9D666|rcsb pdb:5YWZ|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|refseq:NP_001243044.1|refseq:NP_001243045.1|refseq:NP_001243046.1|refseq:NP_001243047.1|refseq:NP_077771.1|dip:DIP-60732N refseq:NP_851289.2|refseq:XP_006531157.1|ensembl:ENSMUSG00000052616(gene)|ensembl:ENSMUST00000064576(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|interpro:IPR000225(Armadillo)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042359|rcsb pdb:1X58|interpro:IPR001005(SANT, DNA-binding)|refseq:XP_017168345.1|dip:DIP-60728N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:GqqeG7DaPNhq8uKIbPelHOotEok10090 rogid:fjP/AyqiLX9oFpDG6/ZPjI2Qu5I10090 rigid:GvOhlfTMsm5jkkCgZVlLDUoCOIo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P70371 uniprotkb:Q8C0V1-1 intact:EBI-6919183|ensembl:ENSMUSP00000140744|uniprotkb:Q9CY71 intact:EBI-16089839|ensembl:ENSMUSP00000067324 psi-mi:terf1_mouse(display_long)|uniprotkb:Terf1(gene name)|psi-mi:Terf1(display_short)|uniprotkb:Trf1(gene name synonym)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym) psi-mi:q8c0v1-1(display_long)|uniprotkb:Terb1(gene name)|psi-mi:Terb1(display_short)|uniprotkb:Ccdc79(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shibuya et al. (2014) pubmed:24413433|doi:10.1038/ncb2896|imex:IM-22407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16089846|imex:IM-22407-2|dip:DIP-196060E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025925(gene)|ensembl:ENSMUST00000188371(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0051301"(cell division)|go:"GO:0005654"(nucleoplasm)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P70371|reactome:R-MMU-110330|reactome:R-MMU-110331|reactome:R-MMU-171319|reactome:R-MMU-174411|reactome:R-MMU-174414|reactome:R-MMU-174417|reactome:R-MMU-174430|reactome:R-MMU-174437|reactome:R-MMU-2559586|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|reactome:R-MMU-9670095|refseq:NP_033378.1|dip:DIP-44231N ensembl:ENSMUSG00000052616(gene)|ensembl:ENSMUST00000064576(transcript)|intact:EBI-11707325(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:jpK0DXdrNcuBqR96dkp45t/W5+M10090 rogid:fjP/AyqiLX9oFpDG6/ZPjI2Qu5I10090 rigid:t2osH9lcOrNl8N0SR6RiIFm9zHs false - sufficient binding region:523-699|mutation disrupting interaction strength:648-648 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70371 uniprotkb:Q8C0V1-1 intact:EBI-6919183|ensembl:ENSMUSP00000140744|uniprotkb:Q9CY71 intact:EBI-16089839|ensembl:ENSMUSP00000067324 psi-mi:terf1_mouse(display_long)|uniprotkb:Terf1(gene name)|psi-mi:Terf1(display_short)|uniprotkb:Trf1(gene name synonym)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym) psi-mi:q8c0v1-1(display_long)|uniprotkb:Terb1(gene name)|psi-mi:Terb1(display_short)|uniprotkb:Ccdc79(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym) psi-mi:"MI:0096"(pull down) Shibuya et al. (2014) pubmed:24413433|doi:10.1038/ncb2896|imex:IM-22407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16089983|imex:IM-22407-9|dip:DIP-196060E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025925(gene)|ensembl:ENSMUST00000188371(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0051301"(cell division)|go:"GO:0005654"(nucleoplasm)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P70371|reactome:R-MMU-110330|reactome:R-MMU-110331|reactome:R-MMU-171319|reactome:R-MMU-174411|reactome:R-MMU-174414|reactome:R-MMU-174417|reactome:R-MMU-174430|reactome:R-MMU-174437|reactome:R-MMU-2559586|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|reactome:R-MMU-9670095|refseq:NP_033378.1|dip:DIP-44231N ensembl:ENSMUSG00000052616(gene)|ensembl:ENSMUST00000064576(transcript)|intact:EBI-11707325(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:jpK0DXdrNcuBqR96dkp45t/W5+M10090 rogid:fjP/AyqiLX9oFpDG6/ZPjI2Qu5I10090 rigid:t2osH9lcOrNl8N0SR6RiIFm9zHs false his tag:n-n sufficient binding region:523-699|maltose binding protein tag:?-? - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9D666 uniprotkb:Q8C0V1-1 intact:EBI-6752574|ensembl:ENSMUSP00000056655|uniprotkb:Q3TIW3|uniprotkb:Q3TV96|uniprotkb:Q6B4H0|uniprotkb:Q80SU8|uniprotkb:Q8BZ99|uniprotkb:Q99P23|uniprotkb:D3Z0V9 intact:EBI-16089839|ensembl:ENSMUSP00000067324 psi-mi:sun1_mouse(display_long)|uniprotkb:Sun1(gene name)|psi-mi:Sun1(display_short)|uniprotkb:Unc84a(gene name synonym)|uniprotkb:Protein unc-84 homolog A(gene name synonym)|uniprotkb:Sad1/unc-84 protein-like 1(gene name synonym) psi-mi:q8c0v1-1(display_long)|uniprotkb:Terb1(gene name)|psi-mi:Terb1(display_short)|uniprotkb:Ccdc79(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shibuya et al. (2014) pubmed:24413433|doi:10.1038/ncb2896|imex:IM-22407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16089962|imex:IM-22407-8|dip:DIP-196061E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000036817(gene)|ensembl:ENSMUST00000058716(transcript)|go:"GO:0001503"(ossification)|go:"GO:0002081"(outer acrosomal membrane)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051642"(centrosome localization)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR018539|interpro:IPR032680|interpro:IPR040994|mint:Q9D666|rcsb pdb:5YWZ|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|refseq:NP_001243044.1|refseq:NP_001243045.1|refseq:NP_001243046.1|refseq:NP_001243047.1|refseq:NP_077771.1|dip:DIP-60732N ensembl:ENSMUSG00000052616(gene)|ensembl:ENSMUST00000064576(transcript)|intact:EBI-11707325(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:GqqeG7DaPNhq8uKIbPelHOotEok10090 rogid:fjP/AyqiLX9oFpDG6/ZPjI2Qu5I10090 rigid:GvOhlfTMsm5jkkCgZVlLDUoCOIo false sufficient binding region:1-210 sufficient binding region:1-371 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8C0V1 uniprotkb:Q8C5S7 intact:EBI-11707325|uniprotkb:A1L2Z9|uniprotkb:E9QPF2|uniprotkb:Q14CI1|uniprotkb:Q8C0N5|ensembl:ENSMUSP00000067324 intact:EBI-8571691|ensembl:ENSMUSP00000002395|uniprotkb:Q3UIN9|intact:UNK-5513402|uniprotkb:Q9JK52 psi-mi:terb1_mouse(display_long)|uniprotkb:Terb1(gene name)|psi-mi:Terb1(display_short)|uniprotkb:Ccdc79(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym) psi-mi:rec8_mouse(display_long)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:Rec8(gene name)|psi-mi:Rec8(display_short)|uniprotkb:Mei8(gene name synonym)|uniprotkb:Rec8L1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shibuya et al. (2014) pubmed:24413433|doi:10.1038/ncb2896|imex:IM-22407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16089940|imex:IM-22407-7|dip:DIP-196058E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_851289.2|refseq:XP_006531157.1|ensembl:ENSMUSG00000052616(gene)|ensembl:ENSMUST00000064576(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|interpro:IPR000225(Armadillo)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042359|rcsb pdb:1X58|interpro:IPR001005(SANT, DNA-binding)|refseq:XP_017168345.1|dip:DIP-60728N ensembl:ENSMUSG00000002324(gene)|ensembl:ENSMUST00000002395(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007141"(male meiosis I)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|go:"GO:0003682"(chromatin binding)|refseq:NP_064386.2|dip:DIP-60730N psi-mi:"MI:0465"(dip) - comment:mint|function:Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:fjP/AyqiLX9oFpDG6/ZPjI2Qu5I10090 rogid:wcsRCrbsVBKW3reh5uW+EN080oU10090 rigid:9c1f4VmuKbrazTSrll/29qBkVGc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8C0V1 uniprotkb:A2AU37 intact:EBI-11707325|uniprotkb:A1L2Z9|uniprotkb:E9QPF2|uniprotkb:Q14CI1|uniprotkb:Q8C0N5|ensembl:ENSMUSP00000067324 intact:EBI-8572441|ensembl:ENSMUSP00000136918|intact:MINT-8174264|uniprotkb:F6KST0|uniprotkb:E5RTP6|intact:MINT-8174092 psi-mi:terb1_mouse(display_long)|uniprotkb:Terb1(gene name)|psi-mi:Terb1(display_short)|uniprotkb:Ccdc79(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym) psi-mi:rd21l_mouse(display_long)|uniprotkb:Rad21l1(gene name)|psi-mi:Rad21l1(display_short)|uniprotkb:Gm14160(gene name synonym)|uniprotkb:Rad21l(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shibuya et al. (2014) pubmed:24413433|doi:10.1038/ncb2896|imex:IM-22407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16089940|imex:IM-22407-7|dip:DIP-196058E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_851289.2|refseq:XP_006531157.1|ensembl:ENSMUSG00000052616(gene)|ensembl:ENSMUST00000064576(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|interpro:IPR000225(Armadillo)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042359|rcsb pdb:1X58|interpro:IPR001005(SANT, DNA-binding)|refseq:XP_017168345.1|dip:DIP-60728N ensembl:ENSMUSG00000074704(gene)|ensembl:ENSMUST00000180195(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|refseq:XP_006500105.1|refseq:XP_006500106.1|refseq:NP_001263329.1|dip:DIP-60729N psi-mi:"MI:0465"(dip) - comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:fjP/AyqiLX9oFpDG6/ZPjI2Qu5I10090 rogid:z8WZFTHSHhOOfT6F/EHl3GVaFEA10090 rigid:9c1f4VmuKbrazTSrll/29qBkVGc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8C0V1 uniprotkb:O70576 intact:EBI-11707325|uniprotkb:A1L2Z9|uniprotkb:E9QPF2|uniprotkb:Q14CI1|uniprotkb:Q8C0N5|ensembl:ENSMUSP00000067324 intact:EBI-8571608|ensembl:ENSMUSP00000040945|ensembl:ENSMUSP00000125523|intact:UNK-5365402|uniprotkb:B2RSV0 psi-mi:terb1_mouse(display_long)|uniprotkb:Terb1(gene name)|psi-mi:Terb1(display_short)|uniprotkb:Ccdc79(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym) psi-mi:stag3_mouse(display_long)|uniprotkb:Stromalin-3(gene name synonym)|uniprotkb:Stag3(gene name)|psi-mi:Stag3(display_short)|uniprotkb:Stromal antigen 3(gene name synonym)|uniprotkb:SCC3 homolog 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shibuya et al. (2014) pubmed:24413433|doi:10.1038/ncb2896|imex:IM-22407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16089940|imex:IM-22407-7|dip:DIP-196058E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_851289.2|refseq:XP_006531157.1|ensembl:ENSMUSG00000052616(gene)|ensembl:ENSMUST00000064576(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|interpro:IPR000225(Armadillo)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042359|rcsb pdb:1X58|interpro:IPR001005(SANT, DNA-binding)|refseq:XP_017168345.1|dip:DIP-60728N refseq:XP_011239250.1|ensembl:ENSMUSG00000036928(gene)|ensembl:ENSMUST00000048028(transcript)|ensembl:ENSMUST00000162245(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0000802"(transverse filament)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007065"(male meiosis sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0008278"(cohesin complex)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0034991"(nuclear meiotic cohesin complex)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:O70576|refseq:XP_006504659.1|refseq:NP_058660.2|dip:DIP-60731N psi-mi:"MI:0465"(dip) - function:Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I|comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:fjP/AyqiLX9oFpDG6/ZPjI2Qu5I10090 rogid:VStlV0vm44TtcEnvNQTLPTFy2ok10090 rigid:9c1f4VmuKbrazTSrll/29qBkVGc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8C0V1 uniprotkb:Q9CW03 intact:EBI-11707325|uniprotkb:A1L2Z9|uniprotkb:E9QPF2|uniprotkb:Q14CI1|uniprotkb:Q8C0N5|ensembl:ENSMUSP00000067324 intact:EBI-2550068|ensembl:ENSMUSP00000025930|uniprotkb:O35667|uniprotkb:Q9QUS3 psi-mi:terb1_mouse(display_long)|uniprotkb:Terb1(gene name)|psi-mi:Terb1(display_short)|uniprotkb:Ccdc79(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym) psi-mi:smc3_mouse(display_long)|uniprotkb:Smc3(gene name)|psi-mi:Smc3(display_short)|uniprotkb:Bam(gene name synonym)|uniprotkb:Bmh(gene name synonym)|uniprotkb:Cspg6(gene name synonym)|uniprotkb:Mmip1(gene name synonym)|uniprotkb:Smc3l1(gene name synonym)|uniprotkb:Smcd(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome segregation protein SmcD(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:Mad member-interacting protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shibuya et al. (2014) pubmed:24413433|doi:10.1038/ncb2896|imex:IM-22407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16089940|imex:IM-22407-7|dip:DIP-196058E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_851289.2|refseq:XP_006531157.1|ensembl:ENSMUSG00000052616(gene)|ensembl:ENSMUST00000064576(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|interpro:IPR000225(Armadillo)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042359|rcsb pdb:1X58|interpro:IPR001005(SANT, DNA-binding)|refseq:XP_017168345.1|dip:DIP-60728N ensembl:ENSMUSG00000024974(gene)|ensembl:ENSMUST00000025930(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9CW03|rcsb pdb:2WD5|reactome:R-MMU-2467813|reactome:R-MMU-2468052|reactome:R-MMU-2470946|reactome:R-MMU-2500257|reactome:R-MMU-3108214|refseq:NP_031816.2|dip:DIP-57028N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:fjP/AyqiLX9oFpDG6/ZPjI2Qu5I10090 rogid:9tJqVTJ2k3viYrJVtDfH2TekFIg10090 rigid:9c1f4VmuKbrazTSrll/29qBkVGc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P70371 uniprotkb:Q8C0V1-1 intact:EBI-6919183|ensembl:ENSMUSP00000140744|uniprotkb:Q9CY71 intact:EBI-16089839|ensembl:ENSMUSP00000067324 psi-mi:terf1_mouse(display_long)|uniprotkb:Terf1(gene name)|psi-mi:Terf1(display_short)|uniprotkb:Trf1(gene name synonym)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym) psi-mi:q8c0v1-1(display_long)|uniprotkb:Terb1(gene name)|psi-mi:Terb1(display_short)|uniprotkb:Ccdc79(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shibuya et al. (2014) pubmed:24413433|doi:10.1038/ncb2896|imex:IM-22407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16089921|imex:IM-22407-6|dip:DIP-196060E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025925(gene)|ensembl:ENSMUST00000188371(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0051301"(cell division)|go:"GO:0005654"(nucleoplasm)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P70371|reactome:R-MMU-110330|reactome:R-MMU-110331|reactome:R-MMU-171319|reactome:R-MMU-174411|reactome:R-MMU-174414|reactome:R-MMU-174417|reactome:R-MMU-174430|reactome:R-MMU-174437|reactome:R-MMU-2559586|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|reactome:R-MMU-9670095|refseq:NP_033378.1|dip:DIP-44231N ensembl:ENSMUSG00000052616(gene)|ensembl:ENSMUST00000064576(transcript)|intact:EBI-11707325(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:jpK0DXdrNcuBqR96dkp45t/W5+M10090 rogid:fjP/AyqiLX9oFpDG6/ZPjI2Qu5I10090 rigid:t2osH9lcOrNl8N0SR6RiIFm9zHs false sufficient binding region:53-255 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O70576 uniprotkb:Q8C0V1-1 intact:EBI-8571608|ensembl:ENSMUSP00000040945|ensembl:ENSMUSP00000125523|intact:UNK-5365402|uniprotkb:B2RSV0 intact:EBI-16089839|ensembl:ENSMUSP00000067324 psi-mi:stag3_mouse(display_long)|uniprotkb:Stromalin-3(gene name synonym)|uniprotkb:Stag3(gene name)|psi-mi:Stag3(display_short)|uniprotkb:Stromal antigen 3(gene name synonym)|uniprotkb:SCC3 homolog 3(gene name synonym) psi-mi:q8c0v1-1(display_long)|uniprotkb:Terb1(gene name)|psi-mi:Terb1(display_short)|uniprotkb:Ccdc79(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shibuya et al. (2014) pubmed:24413433|doi:10.1038/ncb2896|imex:IM-22407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16089902|imex:IM-22407-5|dip:DIP-196059E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011239250.1|ensembl:ENSMUSG00000036928(gene)|ensembl:ENSMUST00000048028(transcript)|ensembl:ENSMUST00000162245(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0000802"(transverse filament)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007065"(male meiosis sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0008278"(cohesin complex)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0034991"(nuclear meiotic cohesin complex)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:O70576|refseq:XP_006504659.1|refseq:NP_058660.2|dip:DIP-60731N ensembl:ENSMUSG00000052616(gene)|ensembl:ENSMUST00000064576(transcript)|intact:EBI-11707325(isoform-parent) psi-mi:"MI:0465"(dip) function:Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I|comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:VStlV0vm44TtcEnvNQTLPTFy2ok10090 rogid:fjP/AyqiLX9oFpDG6/ZPjI2Qu5I10090 rigid:PKz9k0yo6EYuZMwV2lnHpr38k+A false - sufficient binding region:700-768 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O70576 uniprotkb:Q8C0V1-1 intact:EBI-8571608|ensembl:ENSMUSP00000040945|ensembl:ENSMUSP00000125523|intact:UNK-5365402|uniprotkb:B2RSV0 intact:EBI-16089839|ensembl:ENSMUSP00000067324 psi-mi:stag3_mouse(display_long)|uniprotkb:Stromalin-3(gene name synonym)|uniprotkb:Stag3(gene name)|psi-mi:Stag3(display_short)|uniprotkb:Stromal antigen 3(gene name synonym)|uniprotkb:SCC3 homolog 3(gene name synonym) psi-mi:q8c0v1-1(display_long)|uniprotkb:Terb1(gene name)|psi-mi:Terb1(display_short)|uniprotkb:Ccdc79(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 79(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shibuya et al. (2014) pubmed:24413433|doi:10.1038/ncb2896|imex:IM-22407 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16090008|imex:IM-22407-10|dip:DIP-196059E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011239250.1|ensembl:ENSMUSG00000036928(gene)|ensembl:ENSMUST00000048028(transcript)|ensembl:ENSMUST00000162245(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0000802"(transverse filament)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007065"(male meiosis sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0008278"(cohesin complex)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0034991"(nuclear meiotic cohesin complex)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:O70576|refseq:XP_006504659.1|refseq:NP_058660.2|dip:DIP-60731N ensembl:ENSMUSG00000052616(gene)|ensembl:ENSMUST00000064576(transcript)|intact:EBI-11707325(isoform-parent) psi-mi:"MI:0465"(dip) function:Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I|comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:VStlV0vm44TtcEnvNQTLPTFy2ok10090 rogid:fjP/AyqiLX9oFpDG6/ZPjI2Qu5I10090 rigid:PKz9k0yo6EYuZMwV2lnHpr38k+A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)