#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8C3P7	uniprotkb:Q3UIK4	intact:EBI-8311763|intact:MINT-4102524|uniprotkb:Q9CV54|uniprotkb:Q9ERS9|uniprotkb:Q9WUI4	intact:EBI-16089028|ensembl:ENSMUSP00000029759|uniprotkb:Q6ZPL2|uniprotkb:Q80UR9	psi-mi:mta70_mouse(display_long)|uniprotkb:Mettl3(gene name)|psi-mi:Mettl3(display_short)|uniprotkb:Mta70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)	psi-mi:met14_mouse(display_long)|uniprotkb:Mettl14(gene name)|psi-mi:Mettl14(display_short)|uniprotkb:Kiaa1627(gene name synonym)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2014)	pubmed:24394384|doi:10.1038/ncb2902|imex:IM-22406	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16089054|imex:IM-22406-1|dip:DIP-196055E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016556"(mRNA modification)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|reactome:R-MMU-72203|refseq:NP_062695.2|dip:DIP-60724N|mint:Q8C3P7	ensembl:ENSMUSG00000028114(gene)|ensembl:ENSMUST00000029759(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|reactome:R-MMU-72203|refseq:NP_964000.2|dip:DIP-60725N	psi-mi:"MI:0465"(dip)	comment:mint|function:"N6-methyltransferase that methylates adenosine residues of some mRNAs. N6-methyladenosine (m6A), which is present at internal sites of some mRNAs, may play a role in the efficiency of mRNA splicing, transport or translation"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:E9JQPtoHSx+XP10xawHl5sEIUTw10090	rogid:GkIq08a+ap+vZiqnQ/dOGbnCUww10090	rigid:UbPs76DdhA4OT1Ot3zDmSzJKfxY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8C3P7	uniprotkb:Q3UIK4	intact:EBI-8311763|intact:MINT-4102524|uniprotkb:Q9CV54|uniprotkb:Q9ERS9|uniprotkb:Q9WUI4	intact:EBI-16089028|ensembl:ENSMUSP00000029759|uniprotkb:Q6ZPL2|uniprotkb:Q80UR9	psi-mi:mta70_mouse(display_long)|uniprotkb:Mettl3(gene name)|psi-mi:Mettl3(display_short)|uniprotkb:Mta70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)	psi-mi:met14_mouse(display_long)|uniprotkb:Mettl14(gene name)|psi-mi:Mettl14(display_short)|uniprotkb:Kiaa1627(gene name synonym)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2014)	pubmed:24394384|doi:10.1038/ncb2902|imex:IM-22406	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16089071|imex:IM-22406-2|dip:DIP-196055E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016556"(mRNA modification)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|reactome:R-MMU-72203|refseq:NP_062695.2|dip:DIP-60724N|mint:Q8C3P7	ensembl:ENSMUSG00000028114(gene)|ensembl:ENSMUST00000029759(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|reactome:R-MMU-72203|refseq:NP_964000.2|dip:DIP-60725N	psi-mi:"MI:0465"(dip)	comment:mint|function:"N6-methyltransferase that methylates adenosine residues of some mRNAs. N6-methyladenosine (m6A), which is present at internal sites of some mRNAs, may play a role in the efficiency of mRNA splicing, transport or translation"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:E9JQPtoHSx+XP10xawHl5sEIUTw10090	rogid:GkIq08a+ap+vZiqnQ/dOGbnCUww10090	rigid:UbPs76DdhA4OT1Ot3zDmSzJKfxY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q86U44	uniprotkb:Q9HCE5	intact:EBI-11105430|uniprotkb:Q9HB32|uniprotkb:Q86V05|uniprotkb:O14736|ensembl:ENSP00000298717	intact:EBI-6661081|ensembl:ENSP00000373474|uniprotkb:A6NIG1|uniprotkb:Q969V2	psi-mi:mta70_human(display_long)|uniprotkb:N6-adenosine-methyltransferase 70 kDa subunit(gene name synonym)|uniprotkb:METTL3(gene name)|psi-mi:METTL3(display_short)|uniprotkb:MTA70(gene name synonym)|uniprotkb:Methyltransferase-like protein 3(gene name synonym)	psi-mi:met14_human(display_long)|uniprotkb:Methyltransferase-like protein 14(gene name synonym)|uniprotkb:METTL14(gene name)|psi-mi:METTL14(display_short)|uniprotkb:KIAA1627(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wang et al. (2014)	pubmed:24394384|doi:10.1038/ncb2902|imex:IM-22406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16089088|imex:IM-22406-3|dip:DIP-196056E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062826.2|ensembl:ENSG00000165819(gene)|ensembl:ENST00000298717(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0034644"(cellular response to UV)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045087"(innate immune response)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990744"(primary miRNA methylation)|interpro:IPR007757(MT-A70)|interpro:IPR025848|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:5YZ9|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|dip:DIP-60727N	ensembl:ENSG00000145388(gene)|ensembl:ENST00000388822(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042063"(gliogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0080009"(mRNA methylation)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|interpro:IPR007757(MT-A70)|interpro:IPR029063|rcsb pdb:5IL0|rcsb pdb:5IL1|rcsb pdb:5IL2|rcsb pdb:5K7M|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|rcsb pdb:5K7U|rcsb pdb:5K7W|rcsb pdb:5L6D|rcsb pdb:5L6E|rcsb pdb:5TEY|rcsb pdb:6TTP|rcsb pdb:6TTT|rcsb pdb:6TTV|rcsb pdb:6TTW|rcsb pdb:6TTX|rcsb pdb:6TU1|rcsb pdb:6Y4G|rcsb pdb:7ACD|rcsb pdb:7O2I|rcsb pdb:7O2X|reactome:R-HSA-72203|refseq:NP_066012.1|dip:DIP-60726N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)")	-	2017/08/07	2017/08/10	rogid:B7ORoNVaQb6/OA77jPsn558+k409606	rogid:HrwI6DDJQW3GAzFuLRmpzbqfz7A9606	rigid:uC9+mYi7Kaiy3nHOIXKZhXiq7zA	false	flag tag:n-n	his tag:n-n	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)