#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P71451 uniprotkb:Q6XZF7-1 intact:EBI-21019720|uniprotkb:Q799Z7|uniprotkb:Q48787 intact:EBI-16085546|ensembl:ENSP00000315659 psi-mi:inlc_lismg(display_long)|uniprotkb:Internalin-related protein A(gene name synonym)|uniprotkb:irpA(gene name synonym)|uniprotkb:inlC(gene name)|psi-mi:inlC(display_short) psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Polle et al. (2014) pubmed:24332715|doi:10.1016/j.str.2013.10.017|imex:IM-22320 taxid:1334565(lismg)|taxid:1334565(Listeria monocytogenes serotype 1/2a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16085554|imex:IM-22320-1|dip:DIP-195811E|pdbe:4CC4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1XEU|rcsb pdb:4CC4|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024634|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR012569(Leucine-rich repeat, adjacent)|interpro:IPR032675|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2019/01/17 rogid:YQy5YDbuCOKjYgnNFDtfb8jQgDk1334565 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rigid:8JVQT+xS1ueQz5Q7DE7tsukP83s false sufficient binding region:35-297 sufficient binding region:1513-1577 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P71451 uniprotkb:Q6XZF7-1 intact:EBI-21019720|uniprotkb:Q799Z7|uniprotkb:Q48787 intact:EBI-16085546|ensembl:ENSP00000315659 psi-mi:inlc_lismg(display_long)|uniprotkb:Internalin-related protein A(gene name synonym)|uniprotkb:irpA(gene name synonym)|uniprotkb:inlC(gene name)|psi-mi:inlC(display_short) psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Polle et al. (2014) pubmed:24332715|doi:10.1016/j.str.2013.10.017|imex:IM-22320 taxid:1334565(lismg)|taxid:1334565(Listeria monocytogenes serotype 1/2a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16085575|imex:IM-22320-2|dip:DIP-195811E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1XEU|rcsb pdb:4CC4|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024634|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR012569(Leucine-rich repeat, adjacent)|interpro:IPR032675|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2019/01/17 rogid:YQy5YDbuCOKjYgnNFDtfb8jQgDk1334565 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rigid:8JVQT+xS1ueQz5Q7DE7tsukP83s false sufficient binding region:35-297 sufficient binding region:1513-1577 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00401 uniprotkb:Q6XZF7-1 intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9 intact:EBI-16085546|ensembl:ENSP00000315659 psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short) psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Polle et al. (2014) pubmed:24332715|doi:10.1016/j.str.2013.10.017|imex:IM-22320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16085598|imex:IM-22320-3|dip:DIP-195809E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rigid:cgyzjJ8XuX1y2lCe1GPXHgeplnk false sufficient binding region:346-357 sufficient binding region:1513-1577 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P71451 uniprotkb:Q6XZF7-1 intact:EBI-21019720|uniprotkb:Q799Z7|uniprotkb:Q48787 intact:EBI-16085546|ensembl:ENSP00000315659 psi-mi:inlc_lismg(display_long)|uniprotkb:Internalin-related protein A(gene name synonym)|uniprotkb:irpA(gene name synonym)|uniprotkb:inlC(gene name)|psi-mi:inlC(display_short) psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:"MI:0096"(pull down) Polle et al. (2014) pubmed:24332715|doi:10.1016/j.str.2013.10.017|imex:IM-22320 taxid:1334565(lismg)|taxid:1334565(Listeria monocytogenes serotype 1/2a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16085619|imex:IM-22320-4|dip:DIP-195811E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1XEU|rcsb pdb:4CC4|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024634|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR012569(Leucine-rich repeat, adjacent)|interpro:IPR032675|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2019/01/17 rogid:YQy5YDbuCOKjYgnNFDtfb8jQgDk1334565 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rigid:8JVQT+xS1ueQz5Q7DE7tsukP83s false sufficient binding region:35-297|mutation decreasing interaction strength:146-146 sufficient binding region:1513-1577|glutathione s tranferase tag:?-? - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q03173-1 uniprotkb:Q6XZF7-1 intact:EBI-16085647 intact:EBI-16085546|ensembl:ENSP00000315659 psi-mi:q03173-1(display_long)|uniprotkb:Enah(gene name)|psi-mi:Enah(display_short)|uniprotkb:Mena(gene name synonym)|uniprotkb:Ndpp1(gene name synonym)|uniprotkb:Neural variant Mena+++(isoform synonym)|uniprotkb:140 kDa isoform(isoform synonym)|uniprotkb:NPC-derived proline-rich protein 1(gene name synonym) psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Polle et al. (2014) pubmed:24332715|doi:10.1016/j.str.2013.10.017|imex:IM-22320 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16085657|imex:IM-22320-5|dip:DIP-195810E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6083294(isoform-parent) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:MLNC5NL3QIW9Y/aUkc9dTNNAedM10090 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rigid:m0lAaix3isTdZDEC400KoGCClAw false sufficient binding region:547-558 sufficient binding region:1513-1577 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P71451 uniprotkb:Q6XZF7-1 intact:EBI-21019720|uniprotkb:Q799Z7|uniprotkb:Q48787 intact:EBI-16085546|ensembl:ENSP00000315659 psi-mi:inlc_lismg(display_long)|uniprotkb:Internalin-related protein A(gene name synonym)|uniprotkb:irpA(gene name synonym)|uniprotkb:inlC(gene name)|psi-mi:inlC(display_short) psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Polle et al. (2014) pubmed:24332715|doi:10.1016/j.str.2013.10.017|imex:IM-22320 taxid:1334565(lismg)|taxid:1334565(Listeria monocytogenes serotype 1/2a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16085678|imex:IM-22320-6|dip:DIP-195811E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1XEU|rcsb pdb:4CC4|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024634|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR012569(Leucine-rich repeat, adjacent)|interpro:IPR032675|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2019/01/17 rogid:YQy5YDbuCOKjYgnNFDtfb8jQgDk1334565 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rigid:8JVQT+xS1ueQz5Q7DE7tsukP83s false sufficient binding region:35-297|mutation decreasing interaction strength:146-146 sufficient binding region:1513-1577 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00401 uniprotkb:Q6XZF7-1 intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9 intact:EBI-16085546|ensembl:ENSP00000315659 psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short) psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Polle et al. (2014) pubmed:24332715|doi:10.1016/j.str.2013.10.017|imex:IM-22320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16085702|imex:IM-22320-7|dip:DIP-195809E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rigid:cgyzjJ8XuX1y2lCe1GPXHgeplnk false sufficient binding region:346-357 sufficient binding region:1513-1577 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P71451 uniprotkb:Q6XZF7-1 intact:EBI-21019720|uniprotkb:Q799Z7|uniprotkb:Q48787 intact:EBI-16085546|ensembl:ENSP00000315659 psi-mi:inlc_lismg(display_long)|uniprotkb:Internalin-related protein A(gene name synonym)|uniprotkb:irpA(gene name synonym)|uniprotkb:inlC(gene name)|psi-mi:inlC(display_short) psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:"MI:0096"(pull down) Polle et al. (2014) pubmed:24332715|doi:10.1016/j.str.2013.10.017|imex:IM-22320 taxid:1334565(lismg)|taxid:1334565(Listeria monocytogenes serotype 1/2a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16085723|imex:IM-22320-8|dip:DIP-195811E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1XEU|rcsb pdb:4CC4|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024634|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR012569(Leucine-rich repeat, adjacent)|interpro:IPR032675|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2019/01/17 rogid:YQy5YDbuCOKjYgnNFDtfb8jQgDk1334565 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rigid:8JVQT+xS1ueQz5Q7DE7tsukP83s false sufficient binding region:35-297 sufficient binding region:1513-1577|glutathione s tranferase tag:?-?|mutation decreasing interaction strength:1521-1521|mutation decreasing interaction strength:1569-1569 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P71451 uniprotkb:Q6XZF7-1 intact:EBI-21019720|uniprotkb:Q799Z7|uniprotkb:Q48787 intact:EBI-16085546|ensembl:ENSP00000315659 psi-mi:inlc_lismg(display_long)|uniprotkb:Internalin-related protein A(gene name synonym)|uniprotkb:irpA(gene name synonym)|uniprotkb:inlC(gene name)|psi-mi:inlC(display_short) psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Polle et al. (2014) pubmed:24332715|doi:10.1016/j.str.2013.10.017|imex:IM-22320 taxid:1334565(lismg)|taxid:1334565(Listeria monocytogenes serotype 1/2a) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16085776|imex:IM-22320-10|dip:DIP-195811E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1XEU|rcsb pdb:4CC4|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024634|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR012569(Leucine-rich repeat, adjacent)|interpro:IPR032675|interpro:IPR014755(Copper resistance protein CopC/internalin, immunoglobulin-like) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2019/01/17 rogid:YQy5YDbuCOKjYgnNFDtfb8jQgDk1334565 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rigid:8JVQT+xS1ueQz5Q7DE7tsukP83s false sufficient binding region:35-297 sufficient binding region:1513-1577|mutation decreasing interaction strength:1521-1521|mutation decreasing interaction strength:1569-1569 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03173-1 uniprotkb:Q6XZF7-1 intact:EBI-16085647 intact:EBI-16085546|ensembl:ENSP00000315659 psi-mi:q03173-1(display_long)|uniprotkb:Enah(gene name)|psi-mi:Enah(display_short)|uniprotkb:Mena(gene name synonym)|uniprotkb:Ndpp1(gene name synonym)|uniprotkb:Neural variant Mena+++(isoform synonym)|uniprotkb:140 kDa isoform(isoform synonym)|uniprotkb:NPC-derived proline-rich protein 1(gene name synonym) psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Polle et al. (2014) pubmed:24332715|doi:10.1016/j.str.2013.10.017|imex:IM-22320 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16085755|imex:IM-22320-9|dip:DIP-195810E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6083294(isoform-parent) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:MLNC5NL3QIW9Y/aUkc9dTNNAedM10090 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rigid:m0lAaix3isTdZDEC400KoGCClAw false sufficient binding region:547-558 sufficient binding region:1513-1577 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6XZF7-1 uniprotkb:Q6XZF7-1 intact:EBI-16085546|ensembl:ENSP00000315659 intact:EBI-16085546|ensembl:ENSP00000315659 psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Polle et al. (2014) pubmed:24332715|doi:10.1016/j.str.2013.10.017|imex:IM-22320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16085803|imex:IM-22320-11|dip:DIP-195812E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rigid:rL1xvqs9WNtwZtrS5+oJohqi1uU false sufficient binding region:1513-1577 sufficient binding region:1513-1577 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)