#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9Y572	uniprotkb:Q8NB16-1	intact:EBI-298250|intact:EBI-358587|uniprotkb:C4AM87|uniprotkb:Q5J795|uniprotkb:Q5J796|uniprotkb:Q6P5Y1|uniprotkb:B4DJL9|ensembl:ENSP00000216274|ensembl:ENSP00000495490	intact:EBI-16084674|ensembl:ENSP00000308351	psi-mi:ripk3_human(display_long)|uniprotkb:RIPK3(gene name)|psi-mi:RIPK3(display_short)|uniprotkb:RIP3(gene name synonym)|uniprotkb:RIP-like protein kinase 3(gene name synonym)|uniprotkb:Receptor-interacting protein 3(gene name synonym)	psi-mi:q8nb16-1(display_long)|uniprotkb:MLKL(gene name)|psi-mi:MLKL(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cai et al. (2014)	pubmed:24316671|doi:10.1038/ncb2883|imex:IM-22401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16084679|imex:IM-22401-1|dip:DIP-196039E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006862.2|dip:DIP-27519N|ensembl:ENSG00000129465(gene)|ensembl:ENSG00000285379(gene)|ensembl:ENST00000216274(transcript)|ensembl:ENST00000646516(transcript)|go:"GO:0001914"(regulation of T cell mediated cytotoxicity)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007165"(signal transduction)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046006"(regulation of activated T cell proliferation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0070235"(regulation of activation-induced cell death of T cells)|go:"GO:0070266"(necroptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:0097528"(execution phase of necroptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000452"(regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR025735|mint:Q9Y572|rcsb pdb:5V7Z|rcsb pdb:5ZCK|rcsb pdb:7DAC|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-9013957|reactome:R-HSA-937041|reactome:R-HSA-9686347|rcsb pdb:7DA4	ensembl:ENSG00000168404(gene)|ensembl:ENST00000308807(transcript)|intact:EBI-1055040(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:UgojU4aAUAG5RCZ55KR39AelO249606	rogid:xpqkgVEYtiqCJEVp3mmNVyprRQQ9606	rigid:s3iEmfJwRNh6LLNKHBr5li9HT1U	false	flag tag:n-n	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8NB16-1	uniprotkb:Q8NB16-1	intact:EBI-16084674|ensembl:ENSP00000308351	intact:EBI-16084674|ensembl:ENSP00000308351	psi-mi:q8nb16-1(display_long)|uniprotkb:MLKL(gene name)|psi-mi:MLKL(display_short)	psi-mi:q8nb16-1(display_long)|uniprotkb:MLKL(gene name)|psi-mi:MLKL(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cai et al. (2014)	pubmed:24316671|doi:10.1038/ncb2883|imex:IM-22401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16084702|imex:IM-22401-2|dip:DIP-196038E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000168404(gene)|ensembl:ENST00000308807(transcript)|intact:EBI-1055040(isoform-parent)	ensembl:ENSG00000168404(gene)|ensembl:ENST00000308807(transcript)|intact:EBI-1055040(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:xpqkgVEYtiqCJEVp3mmNVyprRQQ9606	rogid:xpqkgVEYtiqCJEVp3mmNVyprRQQ9606	rigid:dpT9mWX8Wf8x7Uce2pz0KVWDVz0	false	flag tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8NB16-1	uniprotkb:Q8NB16-1	intact:EBI-16084674|ensembl:ENSP00000308351	intact:EBI-16084674|ensembl:ENSP00000308351	psi-mi:q8nb16-1(display_long)|uniprotkb:MLKL(gene name)|psi-mi:MLKL(display_short)	psi-mi:q8nb16-1(display_long)|uniprotkb:MLKL(gene name)|psi-mi:MLKL(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cai et al. (2014)	pubmed:24316671|doi:10.1038/ncb2883|imex:IM-22401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16084727|imex:IM-22401-3|dip:DIP-196038E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000168404(gene)|ensembl:ENST00000308807(transcript)|intact:EBI-1055040(isoform-parent)	ensembl:ENSG00000168404(gene)|ensembl:ENST00000308807(transcript)|intact:EBI-1055040(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:xpqkgVEYtiqCJEVp3mmNVyprRQQ9606	rogid:xpqkgVEYtiqCJEVp3mmNVyprRQQ9606	rigid:dpT9mWX8Wf8x7Uce2pz0KVWDVz0	false	flag tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)